GO:0005057

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Name receptor signaling protein activity
Categary Function
Go Slim No
Go Link GO:0005057
Unique Molecular Interactions 696
Total Molecular Interactions 1111
Total Single Events 6462
Pain Genes Associated 28

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for receptor signaling protein activity. They are ordered first by their pain relevance and then by number of times they were reported for receptor signaling protein activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
2 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25
3 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26
4 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 0.76 8.19 6.66
5 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1
6 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 0.74 4.31 6.1
7 INT79759 Ngf Regulation of Il6 1 0.60 4.62 5.62
8 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23
9 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
10 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23
11 INT73539 Binding of Ngf and Ngfr 5 0.45 3.99 4
12 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92
13 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79
14 INT180813 Ngf Positive_regulation of Sorbs1 1 0.04 2.09 3.79
15 INT141254 Ngf Regulation of Transcription of Trpv1 1 0.53 1.37 3.74
16 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
17 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65
18 INT108473 Binding of ADCYAP1 and PNOC 1 0.32 0.64 3.41
19 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
20 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11
21 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
22 INT220062 Binding of NGF and TNFRSF1B 1 0.10 2.21 2.81
23 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
24 INT152113 Binding of NTSR1 and Ngf 3 0.33 2.09 2.62
25 INT170037 Ngf Regulation of Gene_expression of DRGX 1 0.01 1.37 2.46
26 INT103330 Ngf Positive_regulation of Gdnf 2 0.28 1.27 2.45
27 INT103332 Ngf Regulation of Gene_expression of TRPV1 3 0.09 2.6 2.4
28 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
29 INT108987 Ngf Regulation of Gene_expression of Sit1 1 0.00 1.46 2.32
30 INT314205 Ngf Positive_regulation of Phosphorylation of Mapk14 1 0.43 1.24 2.3
31 INT228454 Ngf Positive_regulation of Phosphorylation of Trpv1 1 0.39 2.97 2.26
32 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
33 INT113451 Ngf Regulation of Gene_expression of ASIC3 1 0.07 1.35 2.18
34 INT12140 Ngf Regulation of Chat 1 0.44 1.67 2.18
35 INT212301 NGF Regulation of Gene_expression of TRPV1 1 0.23 2.37 2.13
36 INT351380 Ngf Regulation of TPM1 1 0.44 2.17 2.11
37 INT120319 Ghrh Regulation of Ngf 1 0.25 1.89 2.11
38 INT113452 Ngf Positive_regulation of Gene_expression of ASIC3 1 0.19 1.34 2.08
39 INT93293 Ngf Regulation of Trpv1 2 0.28 0.71 1.9
40 INT166945 Ngf Positive_regulation of Trpv1 1 0.01 0.47 1.88
41 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
42 INT166947 Ngf Positive_regulation of KNG1 1 0.00 0.47 1.86
43 INT276668 Ngf Regulation of Nav1 1 0.09 0.98 1.85
44 INT185097 NGF Regulation of Gene_expression of NAV1 1 0.61 0.81 1.85
45 INT314210 Ngf Regulation of Phosphorylation of Mapk14 1 0.34 0.85 1.84
46 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82
47 INT136273 NGF Regulation of Gene_expression of BDNF 2 0.41 1.14 1.78
48 INT86997 Binding of HIVEP1 and NGF 2 0.03 1.75 1.73
49 INT346217 Braf Positive_regulation of Phosphorylation of Map2k1 1 0.22 3.23 1.72
50 INT80199 Ngf Regulation of Transcription of Rab38 1 0.01 1.48 1.68
51 INT145098 NGF Positive_regulation of BDNF 1 0.66 1.33 1.67
52 INT108066 Binding of NTRK1 and Ngf 3 0.33 2.56 1.66
53 INT167200 Gtf3a Regulation of Gene_expression of Ngf 1 0.08 1.47 1.6
54 INT266768 NGF Positive_regulation of Localization of SFTPA1 1 0.01 1.65 1.6
55 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
56 INT140341 Ngf Positive_regulation of Gene_expression of Oprm1 1 0.02 0.33 1.59
57 INT314214 Mapk14 Positive_regulation of Ngf 1 0.43 1.97 1.56
58 INT170654 Binding of Ntf3 and Ngf 1 0.38 1.66 1.54
59 INT159657 Binding of INSRR and NGF 3 0.00 1.65 1.48
60 INT220058 NGF Positive_regulation of Gene_expression of BDNF 1 0.12 1.31 1.48
61 INT220059 NGF Positive_regulation of Positive_regulation of BDNF 1 0.11 1.31 1.48
62 INT121226 Ngf Regulation of Gene_expression of Trpv1 2 0.62 0.7 1.44
63 INT180789 Ngf Regulation of Localization of Trpv1 1 0.28 1.22 1.44
64 INT266771 Binding of NGF and GOPC 1 0.05 3.23 1.43
65 INT180809 Ngf Positive_regulation of Positive_regulation of Sorbs1 1 0.03 0.84 1.4
66 INT180808 Ngf Positive_regulation of Gene_expression of Sorbs1 1 0.03 0.84 1.4
67 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 0.08 1.11 1.39
68 INT118980 NTRK1 Positive_regulation of NGF 1 0.56 1.45 1.39
69 INT82025 Negative_regulation of Binding of Ntrk1 and Ngf 1 0.47 0.64 1.37
70 INT60992 Ngf Regulation of CRTAC1 1 0.00 0 1.35
71 INT151770 Binding of P2RX3 and Ngf 1 0.18 0.9 1.35
72 INT250934 Binding of BDNF and NGF 3 0.39 0.62 1.34
73 INT140531 Ngf Positive_regulation of DYT10 1 0.72 1.83 1.34
74 INT60989 Ngf Regulation of Th 1 0.17 0 1.34
75 INT300864 Ngf Positive_regulation of Mapk14 2 0.60 1.38 1.32
76 INT180786 Calca Regulation of Positive_regulation of Ngf 1 0.40 0 1.32
77 INT181492 NGF Regulation of TRPV1 1 0.21 0.93 1.31
78 INT132412 Negative_regulation of Ngf Negative_regulation of Ptgs1 1 0.01 0.81 1.31
79 INT314211 Ngf Positive_regulation of Gene_expression of Agtrap 1 0.04 1.15 1.3
80 INT142207 Adcyap1 Positive_regulation of Localization of Gh 1 0.07 0 1.3
81 INT112961 NGF Positive_regulation of ICAM1 1 0.40 0.96 1.28
82 INT314209 Ngf Positive_regulation of Binding of Mapk14 1 0.43 1.48 1.27
83 INT74467 Adcyap1 Positive_regulation of Localization of Gh1 1 0.37 0 1.25
84 INT121729 Negative_regulation of Ngf Positive_regulation of Ephb1 1 0.24 0.69 1.22
85 INT121724 Ngf Positive_regulation of Ephb1 1 0.40 0.68 1.21
86 INT108065 Negative_regulation of Binding of Ngf and IgG-2a 1 0.01 2.38 1.2
87 INT131462 NGF Regulation of Localization of INS 1 0.40 0.97 1.2
88 INT108067 Negative_regulation of Binding of NTRK1 and Ngf 1 0.06 2.38 1.2
89 INT93294 Ngf Regulation of Transcription of Trpv1 1 0.01 0.36 1.19
90 INT108064 Binding of Ngf and IgG-2a 1 0.01 2.36 1.19
91 INT351373 Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
92 INT122370 Positive_regulation of Tacr1 Positive_regulation of Ngf 1 0.30 0.17 1.18
93 INT170655 Binding of Csf2 and Ngf 1 0.36 1.25 1.18
94 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
95 INT351378 Gene_expression of Ngf Positive_regulation of Ntrk1 1 0.35 0.41 1.18
96 INT351377 Gene_expression of Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
97 INT148437 Binding of Bdnf and Ngf 2 0.32 1.9 1.17
98 INT146352 Binding of Rgs14 and Mors1 1 0.23 0.27 1.17
99 INT93290 Ngf Regulation of Transcription of Trpv1 1 0.02 0.34 1.16
100 INT335435 Ngf Positive_regulation of Ltb4r 1 0.52 1.06 1.16
101 INT93289 Ngf Regulation of Trpv1 1 0.05 0.34 1.16
102 INT147446 ADCYAP1 Regulation of Localization of CP 1 0.02 1.12 1.16
103 INT199493 Ngf Regulation of Oprd1 1 0.05 1.05 1.15
104 INT147447 ADCYAP1 Regulation of Localization of RELA 1 0.50 1.12 1.15
105 INT147448 ADCYAP1 Regulation of Localization of NFKB1 1 0.47 1.12 1.15
106 INT122369 Tacr1 Positive_regulation of Ngf 1 0.30 0.16 1.14
107 INT160540 Binding of NGF and PSIP1 2 0.29 1.43 1.12
108 INT242624 Binding of Ngf and Ntrk2 5 0.24 0.48 1.11
109 INT121728 Ngf Positive_regulation of Phosphorylation of Pik3cb 1 0.45 0.69 1.11
110 INT282065 Binding of Calca and Ngf 1 0.14 0.85 1.11
111 INT69889 Ngf Regulation of Localization of Calca 1 0.49 0.1 1.08
112 INT105690 Ngf Positive_regulation of TRPV1 1 0.05 1.43 1.08
113 INT181494 TRPV3 Regulation of Gene_expression of NGF 1 0.24 0.7 1.07
114 INT181493 TRPV4 Regulation of Gene_expression of NGF 1 0.24 0.7 1.07
115 INT120315 Gnrhr Negative_regulation of Positive_regulation of Ngf 1 0.11 0.85 1.07
116 INT120318 Gnrhr Negative_regulation of Ngf 1 0.11 0.85 1.07
117 INT69340 Binding of Igh-6 and Ngf 2 0.06 1.04 1.06
118 INT87320 Ngf Regulation of Gene_expression of Bdnf 2 0.38 0.97 1.06
119 INT120317 Ghrh Regulation of Positive_regulation of Ngf 1 0.25 0.95 1.06
120 INT120311 Ghrh Regulation of Gene_expression of Ngf 1 0.25 0.95 1.06
121 INT93614 Ngf Positive_regulation of Ntrk1 2 0.52 0.85 1.05
122 INT82024 Binding of Ngfr and Ngf 2 0.33 1.48 1.05
123 INT170653 Ngf Regulation of Csf2 1 0.34 1.11 1.05
124 INT76001 Ngf Positive_regulation of Ngfr 1 0.16 0.93 1.05
125 INT48260 Binding of Adcyap1 and Calca 1 0.35 0 1.04
126 INT180806 Ngf Positive_regulation of Regulation of Sorbs1 1 0.03 0.28 1.04
127 INT335401 Hgf Positive_regulation of Ngf 1 0.30 1.13 1.04
128 INT151768 Ngf Positive_regulation of P2rx6 1 0.00 0.81 1.01
129 INT137441 Ngf Negative_regulation of Sema3a 1 0.46 2.07 1.01
130 INT151765 Ngf Positive_regulation of Positive_regulation of P2rx6 1 0.00 0.81 1.01
131 INT113453 Ngf Positive_regulation of JUN 1 0.27 0.6 1.01
132 INT83987 Ngf Regulation of Atf2 1 0.52 0.49 1
133 INT210015 Binding of Adcyap1 and Crh 1 0.47 0.88 1
134 INT86662 Ngf Regulation of SCN10A 1 0.27 1.24 0.99
135 INT145823 Ngf Positive_regulation of Fos 1 0.52 0.95 0.97
136 INT145824 Negative_regulation of Ngf Positive_regulation of Fos 1 0.48 0.95 0.97
137 INT180780 Ngf Regulation of Gdnf 1 0.22 0.28 0.96
138 INT271409 NGF Positive_regulation of TRPV1 1 0.08 2.45 0.94
139 INT271410 NGF Positive_regulation of Gene_expression of TRPV1 1 0.07 2.45 0.94
140 INT70803 Ngf Regulation of Tac4 1 0.06 0.39 0.93
141 INT70802 Ngf Regulation of Ppt1 1 0.21 0.39 0.93
142 INT127673 NGF Regulation of Gene_expression of NTRK1 1 0.48 2.12 0.92
143 INT334529 Pax3 Positive_regulation of Gene_expression of Ngf 1 0.03 0.31 0.91
144 INT13282 Fgf2 Regulation of Ngf 1 0.66 0.21 0.91
145 INT13280 Ngf Regulation of Fgf2 1 0.48 0.2 0.9
146 INT164677 Ngf Positive_regulation of Gene_expression of Fos 1 0.52 0.08 0.89
147 INT84369 Ngf Positive_regulation of KNG1 1 0.04 0.29 0.89
148 INT165540 NGF Positive_regulation of GRIN1 1 0.07 0.17 0.88
149 INT314207 Ngf Negative_regulation of Phosphorylation of Mapk14 1 0.33 0.4 0.88
150 INT297463 Binding of Ntrk1 and Ngf 1 0.10 0.78 0.87
151 INT339318 Ngf Positive_regulation of Pik3cg 1 0.02 0.69 0.87
152 INT122350 Ngf Regulation of Hsd3b1 1 0.34 0 0.87
153 INT73538 Ngf Positive_regulation of Ngfr 2 0.41 1.05 0.85
154 INT120825 Adcyap1 Positive_regulation of Localization of Nos1 1 0.26 0.62 0.85
155 INT114324 RAF1 Positive_regulation of Phosphorylation of ADCY6 1 0.02 0.05 0.85
156 INT114323 Binding of ADCY6 and RAF1 1 0.02 0.05 0.85
157 INT140447 Ngf Regulation of Scn9a 1 0.69 0.16 0.84
158 INT12137 Ngf Regulation of Gad1 1 0.27 0.67 0.83
159 INT145777 Ngf Regulation of Localization of Qrfp 1 0.05 0.35 0.82
160 INT262572 Ngf Positive_regulation of Mapk1 2 0.04 0.52 0.81
161 INT107246 Ngf Regulation of Transcription of ASIC1 1 0.01 0.57 0.81
162 INT103331 Ngf Positive_regulation of Gdnf 1 0.01 0.57 0.8
163 INT282063 Ngf Positive_regulation of Positive_regulation of Prkca 1 0.09 0.18 0.8
164 INT262564 Ngf Positive_regulation of Pik3r1 1 0.08 0.36 0.8
165 INT274785 S100B Positive_regulation of Ngf 1 0.05 0.61 0.8
166 INT262579 Ngf Positive_regulation of Prkca 1 0.07 0.36 0.8
167 INT80200 Negative_regulation of Ngf Negative_regulation of Gene_expression of Rab38 1 0.01 0.68 0.8
168 INT131646 Ngf Positive_regulation of Localization of Calca 1 0.21 0.35 0.8
169 INT192134 Ngf Positive_regulation of Trpv1 1 0.18 1.22 0.79
170 INT21233 Ngf Regulation of Fgf1 1 0.46 0.09 0.79
171 INT42796 Ngf Positive_regulation of Binding of Penk 1 0.56 0.08 0.79
172 INT78714 Ntrk1 Positive_regulation of Ngf 2 0.50 0.63 0.78
173 INT242626 Binding of Ngf and Ntrk3 3 0.15 0.27 0.77
174 INT142208 Adcyap1 Positive_regulation of Transcription of Gh 1 0.05 0 0.77
175 INT103335 Ngf Regulation of TRPV1 1 0.05 0.53 0.77
176 INT142210 Adcyap1 Positive_regulation of Gh 1 0.05 0 0.77
177 INT161951 Positive_regulation of TGFBR1 Positive_regulation of Gene_expression of Ngf 1 0.27 0.99 0.76
178 INT262577 Localization of Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.05 0.92 0.75
179 INT106691 Ngf Positive_regulation of SIGMAR1 1 0.04 0 0.74
180 INT161949 TGFB2 Positive_regulation of Gene_expression of Ngf 1 0.21 0.97 0.74
181 INT298730 PROC Positive_regulation of Gene_expression of Ngf 1 0.00 0.6 0.74
182 INT161950 TGFBR1 Negative_regulation of Localization of Ngf 1 0.23 1.01 0.72
183 INT180769 Calca Regulation of Binding of Ngf 1 0.40 0.15 0.72
184 INT161946 Alk Negative_regulation of Localization of Ngf 1 0.10 1.01 0.72
185 INT180776 Regulation of Ngf Positive_regulation of Trpv1 1 0.28 0.59 0.72
186 INT262580 Ngf Positive_regulation of Hspg2 1 0.03 0.35 0.72
187 INT102123 Ngf Regulation of Gene_expression of Cnr1 1 0.53 0.42 0.71
188 INT274786 Ngf Positive_regulation of Gene_expression of S100B 1 0.05 0.63 0.71
189 INT261845 NGF Positive_regulation of Trpa1 1 0.04 0.73 0.71
190 INT165583 Binding of Bdnf and Ngf 3 0.33 0.81 0.69
191 INT82021 Negative_regulation of Binding of Ngfr and Ngf 1 0.29 0.32 0.69
192 INT82022 Binding of Trib3 and Ngf 1 0.08 0.31 0.68
193 INT82020 Negative_regulation of Binding of Trib3 and Ngf 1 0.07 0.31 0.68
194 INT118979 NGF Positive_regulation of Phosphorylation of NTRK1 1 0.56 0.67 0.67
195 INT119105 Binding of FCGR1A and TNF 1 0.03 1.16 0.67
196 INT74468 Adcyap1 Positive_regulation of Localization of Gnrhr 1 0.27 0 0.67
197 INT119106 Negative_regulation of Binding of FCGR1A and TNF 1 0.03 1.16 0.67
198 INT93615 Ngf Positive_regulation of Lilrb4 1 0.06 0.75 0.67
199 INT192131 Ngf Regulation of Gene_expression of P2rx3 1 0.18 0.3 0.66
200 INT96475 Ngf Positive_regulation of Gene_expression of TRPV1 1 0.03 0.22 0.63

Single Events

The table below shows the top 100 pain related interactions that have been reported for receptor signaling protein activity. They are ordered first by their pain relevance and then by number of times they were reported in receptor signaling protein activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56
2 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238
3 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71
4 INT21793 Positive_regulation of Ngf 154 0.70 94.78 85.27
5 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08
6 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19
7 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45
8 INT12001 Regulation of Ngf 97 0.62 54.64 76.25
9 INT3034 Localization of Ngf 126 0.81 50.81 72.84
10 INT27954 Positive_regulation of Gene_expression of Ngf 87 0.70 57.91 51.96
11 INT19078 Binding of Ngf 78 0.48 31.03 44.33
12 INT20210 Localization of Ngf 69 0.79 46.22 38.57
13 INT8027 Regulation of Gene_expression of Ngf 34 0.62 26.32 31.16
14 INT23435 Positive_regulation of NGF 54 0.70 32.41 30.11
15 INT63769 Regulation of Ngf 44 0.62 21.82 25.84
16 INT48240 Binding of Ngf 46 0.46 23.51 24.42
17 INT62373 Negative_regulation of NGF 34 0.59 25.87 22.38
18 INT30887 Negative_regulation of Ngf 56 0.59 32.96 20.86
19 INT65907 Negative_regulation of Gene_expression of Ngf 36 0.59 19.5 20.03
20 INT64261 Negative_regulation of Positive_regulation of Ngf 21 0.59 16.28 19.78
21 INT49922 Positive_regulation of Positive_regulation of Ngf 21 0.67 14.46 17.68
22 INT15358 Transcription of Ngf 29 0.72 10.43 16.94
23 INT54077 Gene_expression of Adcyap1 62 0.78 23.17 16.75
24 INT20216 Localization of NGF 40 0.80 18.16 16.61
25 INT84924 Positive_regulation of Gene_expression of NGF 29 0.68 17.91 16.46
26 INT48238 Regulation of Gene_expression of Ngf 25 0.62 11.48 16.42
27 INT71150 Binding of NGF 22 0.46 13.67 14.81
28 INT58896 Localization of Adcyap1 35 0.81 4.57 14.77
29 INT48259 Positive_regulation of Adcyap1 33 0.67 10.94 14.39
30 INT65965 Gene_expression of Adcyap1 52 0.78 22.53 13.14
31 INT85048 Regulation of NGF 19 0.62 11.61 10.5
32 INT27955 Negative_regulation of Gene_expression of Ngf 16 0.59 10.43 10.17
33 INT81264 Positive_regulation of Localization of Ngf 13 0.58 9.82 9.53
34 INT75997 Positive_regulation of Localization of Ngf 14 0.69 7.78 9.41
35 INT147452 Gene_expression of ADCYAP1 14 0.77 12.54 9.28
36 INT106199 Positive_regulation of Adcyap1 32 0.68 13.68 9.14
37 INT52116 Regulation of Adcyap1 20 0.53 6.1 8.14
38 INT65964 Regulation of Adcyap1 13 0.45 10.1 7.54
39 INT63373 Negative_regulation of Gene_expression of NGF 14 0.57 8.9 7.1
40 INT49761 Regulation of Positive_regulation of Ngf 6 0.62 3.83 7.1
41 INT73155 Positive_regulation of Positive_regulation of Ngf 11 0.70 5.11 6.7
42 INT129015 Phosphorylation of Ngf 6 0.73 5.92 6.6
43 INT63374 Regulation of Gene_expression of NGF 12 0.45 5.6 6.4
44 INT43224 Negative_regulation of Adcyap1 17 0.54 3.69 6.19
45 INT62611 Phosphorylation of Ngf 13 0.82 1.12 5.8
46 INT49701 Negative_regulation of Localization of Ngf 9 0.58 3.01 5.75
47 INT16262 Positive_regulation of Transcription of Ngf 8 0.50 4.02 5.48
48 INT27952 Transcription of Ngf 12 0.72 5.34 5.43
49 INT14357 Positive_regulation of FCGR1A 10 0.44 7.14 5.4
50 INT152742 Positive_regulation of Localization of NGF 7 0.50 4.44 5.02
51 INT199560 Binding of Braf 4 0.30 8.83 4.8
52 INT66048 Positive_regulation of Gene_expression of Adcyap1 5 0.49 8.21 4.52
53 INT106548 Localization of Adcyap1 14 0.80 5.05 4.33
54 INT155512 Positive_regulation of Braf 2 0.49 7.88 4.2
55 INT105171 Phosphorylation of RAF1 11 0.74 2.33 4.19
56 INT138209 Positive_regulation of Localization of Adcyap1 2 0.41 2.07 4.08
57 INT49700 Regulation of Localization of Ngf 6 0.59 1.18 3.95
58 INT137268 Regulation of Binding of Ngf 5 0.61 1.63 3.91
59 INT146350 Phosphorylation of Rgs14 1 0.80 0.79 3.77
60 INT115877 Negative_regulation of Adcyap1 14 0.59 5.31 3.74
61 INT59154 Binding of Adcyap1 12 0.48 4.16 3.71
62 INT84925 Transcription of NGF 11 0.65 4.13 3.65
63 INT58897 Regulation of Localization of Adcyap1 4 0.45 1.82 3.48
64 INT19491 Gene_expression of CD19 44 0.75 28.8 3.47
65 INT15299 Gene_expression of IL1RL1 37 0.69 10.09 3.43
66 INT139807 Gene_expression of Braf 7 0.51 8.78 3.34
67 INT119421 Negative_regulation of RAF1 10 0.41 6.94 3.31
68 INT120823 Positive_regulation of Gene_expression of Adcyap1 10 0.68 6.71 3.22
69 INT31940 Binding of FCGR1A 6 0.35 2.16 3.1
70 INT346210 Phosphorylation of Braf 1 0.44 5.3 2.77
71 INT45014 Regulation of IL1RL1 12 0.14 1.87 2.67
72 INT196919 Regulation of Braf 3 0.32 6.14 2.55
73 INT93059 Positive_regulation of Siglece 3 0.38 5.96 2.49
74 INT59119 Positive_regulation of ADCYAP1 9 0.69 4.68 2.48
75 INT87319 Regulation of Negative_regulation of Ngf 3 0.61 2.4 2.38
76 INT97485 Localization of ADCYAP1 4 0.78 0.24 2.35
77 INT114327 Positive_regulation of RAF1 26 0.51 20.87 2.32
78 INT62612 Negative_regulation of Transcription of Ngf 5 0.43 1.33 2.1
79 INT147453 Positive_regulation of Gene_expression of ADCYAP1 3 0.69 3.49 2.1
80 INT63375 Positive_regulation of Positive_regulation of NGF 2 0.48 1.17 2.08
81 INT25286 Localization of IL1RL1 7 0.56 3.17 2.07
82 INT147451 Regulation of Gene_expression of ADCYAP1 3 0.61 1.88 2.04
83 INT60943 Positive_regulation of Transcription of Ngf 3 0.50 2.15 1.99
84 INT54076 Transcription of Adcyap1 4 0.67 1.65 1.98
85 INT99970 Regulation of Binding of NGF 2 0.27 2.35 1.93
86 INT77300 Negative_regulation of Positive_regulation of Adcyap1 3 0.35 0 1.88
87 INT95650 Negative_regulation of Positive_regulation of Ngf 6 0.43 4.41 1.84
88 INT66047 Regulation of Gene_expression of Adcyap1 2 0.58 3.36 1.84
89 INT26318 Positive_regulation of CD19 7 0.67 5.61 1.8
90 INT84820 Negative_regulation of Negative_regulation of Ngf 5 0.59 2.5 1.79
91 INT249342 Gene_expression of TYROBP 3 0.73 16.71 1.79
92 INT24079 Positive_regulation of Negative_regulation of Ngf 4 0.50 1.02 1.68
93 INT157435 Regulation of Transcription of Ngf 2 0.45 1.29 1.65
94 INT27953 Regulation of Transcription of Ngf 3 0.27 1.1 1.64
95 INT126276 Regulation of Rgs14 1 0.39 0.71 1.63
96 INT82143 Gene_expression of Raf1 2 0.18 0.33 1.59
97 INT30884 Negative_regulation of Negative_regulation of Ngf 2 0.58 0.08 1.49
98 INT131457 Gene_expression of FCGR1A 11 0.75 4.88 1.45
99 INT159303 Regulation of Negative_regulation of NGF 1 0.44 0.96 1.39
100 INT220073 Negative_regulation of Binding of NGF 1 0.23 1.1 1.39
101 INT82140 Negative_regulation of Raf1 3 0.14 1.7 1.38
102 INT82141 Positive_regulation of Raf1 2 0.12 0.81 1.38
103 INT59153 Positive_regulation of Binding of Adcyap1 3 0.43 0.56 1.37
104 INT82139 Positive_regulation of Gene_expression of Raf1 2 0.12 0.28 1.29
105 INT122368 Regulation of Regulation of Ngf 1 0.27 1.37 1.27
106 INT146351 Positive_regulation of Phosphorylation of Rgs14 1 0.45 0.27 1.23
107 INT187156 Binding of CD19 10 0.29 2.05 1.2
108 INT75995 Positive_regulation of Regulation of Ngf 2 0.45 1.21 1.2
109 INT127805 Positive_regulation of Phosphorylation of RAF1 3 0.45 1.21 1.17
110 INT140973 Negative_regulation of Binding of Ngf 2 0.43 1.93 1.17
111 INT85995 Gene_expression of NCR1 5 0.45 3.39 1.15
112 INT268662 Regulation of Araf 4 0.17 2.5 1.13
113 INT28493 Positive_regulation of IL1RL1 10 0.47 3.44 1.11
114 INT11817 Protein_catabolism of Ngf 2 0.88 1.01 1.11
115 INT106549 Binding of Adcyap1 3 0.35 1.83 1.08
116 INT268379 Gene_expression of ARAF 22 0.16 9.34 1.07
117 INT82138 Negative_regulation of Gene_expression of Raf1 1 0.01 0.28 1.04
118 INT82142 Negative_regulation of Positive_regulation of Raf1 1 0.01 0.28 1.04
119 INT126279 Gene_expression of Rgs14 1 0.67 0.34 0.98
120 INT187347 Negative_regulation of Localization of Ngf 2 0.42 0.13 0.95
121 INT166379 Gene_expression of Araf 11 0.49 5.2 0.9
122 INT75549 Protein_catabolism of Ngf 3 0.88 1.59 0.88
123 INT7552 Negative_regulation of IL1RL1 12 0.42 1.68 0.87
124 INT115176 Positive_regulation of Phosphorylation of Ngf 3 0.47 0.4 0.87
125 INT160830 Gene_expression of Siglece 6 0.39 2.37 0.85
126 INT43221 Negative_regulation of Negative_regulation of Adcyap1 1 0.18 0 0.85
127 INT103718 Positive_regulation of Negative_regulation of Ngf 2 0.47 1.75 0.83
128 INT181129 Positive_regulation of Araf 8 0.21 4.3 0.79
129 INT112386 Positive_regulation of Gene_expression of IL1RL1 4 0.47 2.72 0.77
130 INT87734 Regulation of ARAF 4 0.23 2.44 0.76
131 INT312811 Regulation of Localization of Ngf 1 0.16 0.3 0.74
132 INT132521 Gene_expression of BRAF 14 0.65 13.59 0.73
133 INT144880 Negative_regulation of DAXX 4 0.23 2.15 0.73
134 INT93111 Phosphorylation of NGF 1 0.49 0.61 0.73
135 INT210014 Regulation of Binding of Adcyap1 1 0.38 0.25 0.73
136 INT147109 Negative_regulation of Localization of NGF 1 0.57 0.24 0.71
137 INT210012 Regulation of Transcription of Adcyap1 1 0.44 0.48 0.7
138 INT210011 Negative_regulation of Gene_expression of Adcyap1 1 0.36 1.22 0.69
139 INT164916 Binding of IL1RL1 9 0.33 1.84 0.66
140 INT285478 Negative_regulation of Rgs14 1 0.27 1.25 0.6
141 INT223455 Gene_expression of Dok4 1 0.65 0.42 0.6
142 INT138836 Regulation of FCGR1A 1 0.37 1.02 0.58
143 INT137580 Negative_regulation of Gene_expression of Adcyap1 3 0.43 0.15 0.57
144 INT214559 Positive_regulation of Gene_expression of CD19 4 0.38 1.34 0.54
145 INT93520 Negative_regulation of ADCYAP1 3 0.42 0.32 0.53
146 INT82749 Negative_regulation of Gene_expression of IL1RL1 4 0.40 2 0.52
147 INT236928 Negative_regulation of Araf 1 0.06 1.49 0.5
148 INT68358 Regulation of Positive_regulation of Adcyap1 1 0.44 0 0.5
149 INT171362 Gene_expression of Raf1 13 0.66 8.36 0.49
150 INT148952 Regulation of Phosphorylation of Ngf 1 0.03 0.17 0.49
151 INT119016 Negative_regulation of CD19 5 0.37 3.65 0.48
152 INT161378 Binding of BRAF 1 0.08 2.24 0.48
153 INT203480 Negative_regulation of Transcription of Adcyap1 1 0.41 0.81 0.47
154 INT97486 Positive_regulation of Localization of ADCYAP1 1 0.67 0 0.47
155 INT203479 Transcription of Adcyap1 1 0.67 0.81 0.47
156 INT155088 Positive_regulation of DAXX 1 0.22 1.27 0.45
157 INT346209 Localization of Braf 1 0.49 0.78 0.44
158 INT115876 Regulation of Gene_expression of Adcyap1 1 0.38 0.47 0.44
159 INT323167 Negative_regulation of Phosphorylation of RAF1 1 0.08 0 0.43
160 INT252737 Gene_expression of RAF1 12 0.58 10.97 0.42
161 INT199011 Binding of Lat 11 0.32 6.03 0.42
162 INT187160 Negative_regulation of Binding of CD19 1 0.20 0.63 0.41
163 INT233475 Gene_expression of Gpr85 1 0.66 1.78 0.39
164 INT223451 Transcription of Dok4 1 0.45 0.33 0.39
165 INT71095 Regulation of ADCYAP1 1 0.45 0.48 0.38
166 INT275954 Regulation of Lat 4 0.54 0.75 0.37
167 INT346208 Regulation of Positive_regulation of Braf 1 0.19 0.7 0.37
168 INT337703 Regulation of Localization of NGF 1 0.31 1.03 0.37
169 INT236846 Localization of CD19 3 0.68 1.55 0.36
170 INT181130 Positive_regulation of Gene_expression of Raf1 1 0.59 2.29 0.36
171 INT164919 Transcription of IL1RL1 2 0.64 2.74 0.35
172 INT268386 Positive_regulation of ARAF 6 0.17 4.84 0.33
173 INT70133 Positive_regulation of Positive_regulation of FCGR1A 1 0.44 0.73 0.33
174 INT236623 Positive_regulation of BRAF 3 0.45 2.05 0.32
175 INT342548 Localization of DCLK1 1 0.16 0.94 0.27
176 INT327250 Regulation of Positive_regulation of Araf 1 0.09 1.09 0.26
177 INT319433 Positive_regulation of Localization of IL1RL1 1 0.35 1.39 0.26
178 INT327266 Positive_regulation of Positive_regulation of Araf 1 0.07 1.08 0.26
179 INT95651 Positive_regulation of Binding of Ngf 3 0.50 0.48 0.25
180 INT268380 Positive_regulation of Positive_regulation of ARAF 3 0.12 3.49 0.25
181 INT190727 Negative_regulation of Positive_regulation of Adcyap1 1 0.27 0 0.25
182 INT69072 Positive_regulation of Negative_regulation of Adcyap1 1 0.50 0 0.25
183 INT199569 Negative_regulation of Braf 4 0.36 3.73 0.23
184 INT252745 Positive_regulation of Positive_regulation of RAF1 3 0.20 4.62 0.21
185 INT214813 Negative_regulation of Siglece 1 0.03 0.59 0.21
186 INT275434 Regulation of TYROBP 1 0.43 0.78 0.21
187 INT275435 Regulation of Gene_expression of TYROBP 1 0.58 2.33 0.21
188 INT224563 Positive_regulation of Positive_regulation of Raf1 1 0.11 0 0.2
189 INT236840 Positive_regulation of Localization of CD19 1 0.45 0.78 0.19
190 INT181125 Transcription of Raf1 2 0.59 1.14 0.18
191 INT132524 Positive_regulation of Gene_expression of BRAF 1 0.37 0.95 0.18
192 INT354425 Regulation of NCR1 1 0.23 0 0.18
193 INT284590 Regulation of Localization of Adcyap1 1 0.07 0 0.17
194 INT270152 Positive_regulation of Lat 6 0.44 11.1 0.16
195 INT181127 Phosphorylation of Araf 2 0.37 0.51 0.16
196 INT214810 Regulation of Siglece 1 0.02 0.79 0.14
197 INT319410 Positive_regulation of Transcription of IL1RL1 1 0.48 1.49 0.14
198 INT342546 Gene_expression of DCLK1 1 0.14 2.1 0.14
199 INT330973 Regulation of Phosphorylation of RAF1 1 0.30 1.09 0.14
200 INT275432 Positive_regulation of TYROBP 1 0.47 0.29 0.13
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