GO:0005078

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Name MAP-kinase scaffold activity
Categary Function
Go Slim No
Go Link GO:0005078
Unique Molecular Interactions 19
Total Molecular Interactions 26
Total Single Events 86
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for MAP-kinase scaffold activity. They are ordered first by their pain relevance and then by number of times they were reported for MAP-kinase scaffold activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT330104 Binding of Sh3rf1 and Rac1 1 0.13 2.41 0.62
2 INT171914 MAPK8IP3 Positive_regulation of Gene_expression of MAPK1 1 0.06 1.55 0.52
3 INT348016 Binding of Mapk8 and Mapk8ip3 1 0.04 2.09 0.32
4 INT330100 Binding of Sh3rf1 and Map3k11 1 0.08 1.21 0.31
5 INT171912 MAPK8IP3 Positive_regulation of MAPK9 1 0.06 0.78 0.26
6 INT171911 MAPK8IP3 Positive_regulation of Gene_expression of MAPK14 1 0.05 0.77 0.26
7 INT348034 Mapk8ip3 Negative_regulation of Mapk8 1 0.05 0.98 0.16
8 INT348019 Negative_regulation of Binding of Mapk8 and Mapk8ip3 1 0.05 1.04 0.16
9 INT254643 Binding of Mapk8ip1 and Slc9a3r2 1 0.00 0.27 0.12
10 INT143647 Negative_regulation of Mapk8ip1 Negative_regulation of Gene_expression of Fas 1 0.02 0.15 0.05
11 INT286420 Binding of Fgf13 and Mapk8ip3 1 0.36 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for MAP-kinase scaffold activity. They are ordered first by their pain relevance and then by number of times they were reported in MAP-kinase scaffold activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT133085 Gene_expression of Mapk8ip1 7 0.66 6.13 2.98
2 INT95737 Positive_regulation of Phosphorylation of Mapk8ip1 2 0.06 3.27 2.74
3 INT133083 Positive_regulation of Gene_expression of Mapk8ip1 1 0.07 3.27 2.47
4 INT95736 Phosphorylation of Mapk8ip1 2 0.10 2.84 2.32
5 INT143646 Negative_regulation of Mapk8ip1 5 0.03 5.46 1.28
6 INT167981 Negative_regulation of Negative_regulation of Mapk8ip1 1 0.01 0.91 0.45
7 INT179413 Positive_regulation of Mapk8ip1 1 0.01 0.97 0.4
8 INT330091 Binding of Sh3rf1 1 0.15 1.2 0.31
9 INT95740 Negative_regulation of Phosphorylation of Mapk8ip1 1 0.01 0 0.27
10 INT280787 Gene_expression of Mapk8ip3 1 0.01 0.24 0.07
11 INT254642 Binding of Mapk8ip1 1 0.32 0.22 0.07
12 INT285978 Negative_regulation of Gene_expression of Mapk8ip1 1 0.01 0.66 0.04
13 INT286395 Negative_regulation of Transcription of Mapk8ip3 1 0.55 0 0
14 INT286400 Transcription of Mapk8ip3 1 0.68 0 0
15 INT286397 Negative_regulation of Mapk8ip3 1 0.41 0.06 0
16 INT286391 Positive_regulation of Mapk8ip3 1 0.44 0.06 0
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