GO:0005086

From wiki-pain
Jump to: navigation, search
Name ARF guanyl-nucleotide exchange factor activity
Categary Function
Go Slim No
Go Link GO:0005086
Unique Molecular Interactions 43
Total Molecular Interactions 60
Total Single Events 380
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for ARF guanyl-nucleotide exchange factor activity. They are ordered first by their pain relevance and then by number of times they were reported for ARF guanyl-nucleotide exchange factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT133937 Binding of OPRK1 and ARFGEF1 1 0.01 0 1.39
2 INT232621 Binding of Gria1 and Psd 1 0.10 0.29 0.77
3 INT133941 ARFGEF1 Positive_regulation of OPRK1 1 0.02 0 0.76
4 INT133940 Binding of OPRD1 and ARFGEF1 1 0.02 0 0.73
5 INT133938 Binding of OPRL1 and ARFGEF1 1 0.00 0 0.73
6 INT133942 Binding of YY1 and ARFGEF1 1 0.05 0 0.69
7 INT232615 Psd Regulation of Cysltr1 1 0.02 0.58 0.68
8 INT114036 Binding of Grin1 and Psd 1 0.24 0.45 0.68
9 INT117310 HP Regulation of Gbf1 1 0.00 0.86 0.46
10 INT71575 Negative_regulation of Nppb Positive_regulation of Gbf1 1 0.02 0.08 0.38
11 INT71574 Nppb Positive_regulation of Gbf1 1 0.02 0.08 0.38
12 INT198779 Binding of Dlg4 and Psd 10 0.25 0.09 0.31
13 INT26185 Positive_regulation of Binding of GREM1 and Cyth2 1 0.00 0 0.22
14 INT26186 Binding of GREM1 and Cyth2 1 0.00 0 0.22
15 INT263747 Neto1 Positive_regulation of Psd 1 0.24 0 0.14
16 INT103425 Binding of Adra2a and Cyth2 1 0.00 0 0.14
17 INT287262 Binding of Cyth3 and Shbdp1 1 0.00 0.15 0.14
18 INT303166 Binding of Dlgap1 and Psd 1 0.08 0.31 0.1
19 INT257466 Psd Negative_regulation of Gene_expression of Adipoq 1 0.22 0.66 0.08
20 INT219149 FBXO8 Positive_regulation of Localization of IL10 1 0.01 0.14 0.05
21 INT198777 Binding of Psd and Psds1 1 0.05 0 0.04
22 INT303248 LILRA3 Positive_regulation of Protein_catabolism of Psd 1 0.01 0.2 0.03
23 INT198780 Regulation of Binding of Dlg4 and Psd 1 0.14 0 0.03
24 INT107180 asa Positive_regulation of Gbf1 1 0.01 0.14 0
25 INT303167 Binding of Trim3 and Psd 1 0.18 0 0
26 INT354967 Binding of Psd and Dlgap1 1 0.15 0.09 0
27 INT272008 Tsc1 Negative_regulation of Binding of HERC1 1 0.01 0.32 0
28 INT263744 Binding of Psd and Neto1 1 0.19 0 0
29 INT272264 Dlg4 Regulation of Psd 1 0.22 0.09 0
30 INT354969 Binding of Rapsn and Psd 1 0.01 0.09 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for ARF guanyl-nucleotide exchange factor activity. They are ordered first by their pain relevance and then by number of times they were reported in ARF guanyl-nucleotide exchange factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT60590 Positive_regulation of Gbf1 25 0.39 12.5 11.79
2 INT133953 Gene_expression of ARFGEF1 1 0.07 0 3.87
3 INT4012 Negative_regulation of Psd 23 0.52 14.12 3.81
4 INT51581 Negative_regulation of Gbf1 8 0.36 3.96 3.61
5 INT198753 Binding of Psd 18 0.20 1.66 2.84
6 INT27207 Gene_expression of Psd 31 0.73 15.44 2.75
7 INT98871 Regulation of Psd 8 0.42 4.55 2.57
8 INT60588 Negative_regulation of Positive_regulation of Gbf1 3 0.36 0.67 1.87
9 INT60589 Positive_regulation of Positive_regulation of Gbf1 4 0.39 1.7 1.59
10 INT198743 Gene_expression of Psd 11 0.37 1.34 1.5
11 INT97216 Positive_regulation of Psd 13 0.45 7.04 1.25
12 INT25833 Positive_regulation of Cyth2 1 0.10 0 1.15
13 INT51583 Gene_expression of Gbf1 5 0.24 2.3 1.11
14 INT167182 Binding of Psd 9 0.41 13.08 1.06
15 INT139150 Regulation of Psd 4 0.35 0.28 0.98
16 INT161766 Localization of Psd 7 0.75 3.53 0.96
17 INT114035 Negative_regulation of Gene_expression of Psd 3 0.26 1.06 0.75
18 INT26183 Binding of Cyth2 3 0.08 0 0.74
19 INT66298 Localization of Gbf1 1 0.22 0.19 0.69
20 INT198751 Negative_regulation of Psd 2 0.27 0.47 0.66
21 INT133947 Positive_regulation of Localization of ARFGEF1 1 0.05 0 0.62
22 INT133948 Localization of ARFGEF1 1 0.09 0 0.62
23 INT60587 Regulation of Gbf1 2 0.23 0.73 0.6
24 INT242351 Regulation of Positive_regulation of Psd 1 0.37 1.34 0.46
25 INT43586 Positive_regulation of Cyth3 1 0.01 0.1 0.44
26 INT158313 Positive_regulation of Psd 3 0.39 1.96 0.43
27 INT60591 Positive_regulation of Negative_regulation of Gbf1 1 0.39 0 0.43
28 INT60586 Regulation of Positive_regulation of Gbf1 1 0.23 0 0.37
29 INT209226 Localization of Psd 2 0.31 0.09 0.34
30 INT272256 Protein_catabolism of Psd 3 0.49 2.66 0.19
31 INT259536 Transcription of Psd 2 0.38 1.25 0.16
32 INT272259 Regulation of Regulation of Psd 1 0.22 0.15 0.12
33 INT294376 Phosphorylation of Psd 1 0.34 0 0.1
34 INT294377 Regulation of Phosphorylation of Psd 1 0.15 0 0.1
35 INT61383 Binding of Cyth3 1 0.02 0.48 0.06
36 INT320425 Regulation of Localization of Psd 1 0.11 0 0.05
37 INT180287 Negative_regulation of Negative_regulation of Psd 1 0.00 1.09 0.05
38 INT266287 Negative_regulation of Gene_expression of Psd 2 0.23 1.42 0
39 INT271964 Binding of HERC1 1 0.01 0.31 0
40 INT303194 Positive_regulation of Protein_catabolism of Psd 1 0.16 0 0
41 INT83002 Gene_expression of Cyth2 1 0.22 0 0
42 INT272956 Positive_regulation of Binding of Psd 1 0.28 2.66 0
43 INT303235 Positive_regulation of Gene_expression of Psd 1 0.19 0 0
44 INT51582 Positive_regulation of Gene_expression of Gbf1 1 0.18 0 0
45 INT198737 Protein_catabolism of Psd 1 0.34 0.1 0
46 INT303222 Regulation of Protein_catabolism of Psd 1 0.10 0 0
47 INT198742 Regulation of Binding of Psd 1 0.20 0 0
48 INT266293 Positive_regulation of Gene_expression of Psd 1 0.27 0.25 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox