GO:0005088

From wiki-pain
Jump to: navigation, search
Name Ras guanyl-nucleotide exchange factor activity
Categary Function
Go Slim No
Go Link GO:0005088
Unique Molecular Interactions 21
Total Molecular Interactions 32
Total Single Events 182
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for Ras guanyl-nucleotide exchange factor activity. They are ordered first by their pain relevance and then by number of times they were reported for Ras guanyl-nucleotide exchange factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT65014 SOS1 Positive_regulation of Gene_expression of IL6 1 0.45 0.42 0.6
2 INT27064 Kndc1 Positive_regulation of Localization of Oxt 1 0.00 0 0.46
3 INT27065 Kndc1 Positive_regulation of Localization of Avp 1 0.00 0 0.46
4 INT291625 Binding of CSTA and RAPGEF5 1 0.03 4.81 0.37
5 INT65013 SOS1 Positive_regulation of Gene_expression of PTGER2 1 0.09 0.16 0.22
6 INT225743 Binding of SOS1 and RANBP9 1 0.00 0.09 0.1
7 INT291621 RAPGEF5 Regulation of CSTA 1 0.04 0.43 0.03
8 INT225909 Binding of GRB2 and SOS1 1 0.01 0.11 0
9 INT115368 Binding of GDNF and RAPGEF5 1 0.32 0 0
10 INT345287 Binding of SCN10A and RAPGEF5 1 0.01 0.67 0
11 INT24480 Binding of ERF and RASGEF1A 1 0.00 0 0
12 INT263248 Binding of ADD1 and RAPGEF5 1 0.01 0.84 0
13 INT303334 Binding of SOS1 and Grb2 1 0.00 0.11 0
14 INT24479 Binding of CELA2A and RASGEF1A 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for Ras guanyl-nucleotide exchange factor activity. They are ordered first by their pain relevance and then by number of times they were reported in Ras guanyl-nucleotide exchange factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT4679 Negative_regulation of RAPGEF5 55 0.57 47.51 4.55
2 INT37485 Regulation of RAPGEF5 10 0.44 6.64 1.51
3 INT47734 Positive_regulation of RAPGEF5 19 0.56 13.16 1.41
4 INT188774 Binding of RAPGEF5 12 0.29 13.55 1.04
5 INT4681 Localization of RAPGEF5 12 0.68 8.69 0.93
6 INT114176 Positive_regulation of SOS1 3 0.20 1.5 0.86
7 INT22096 Negative_regulation of SOS1 4 0.25 1.63 0.71
8 INT65016 Gene_expression of SOS1 4 0.61 0.47 0.65
9 INT65019 Regulation of SOS1 2 0.56 0.42 0.49
10 INT27060 Positive_regulation of Localization of Kndc1 1 0.00 0 0.49
11 INT27061 Localization of Kndc1 1 0.01 0 0.48
12 INT11118 Gene_expression of RAPGEF5 13 0.65 9.35 0.43
13 INT270743 Negative_regulation of Localization of RAPGEF5 1 0.11 1.6 0.27
14 INT65017 Negative_regulation of Gene_expression of SOS1 1 0.39 0.16 0.23
15 INT65022 Positive_regulation of Gene_expression of SOS1 1 0.45 0.16 0.22
16 INT119070 Phosphorylation of SOS1 2 0.79 0.94 0.15
17 INT279950 Positive_regulation of Positive_regulation of RAPGEF5 1 0.24 1.56 0.1
18 INT164479 Positive_regulation of Gene_expression of RAPGEF5 2 0.49 1.3 0.08
19 INT199984 Regulation of RASGEF1A 1 0.01 0.06 0.08
20 INT4680 Positive_regulation of Negative_regulation of RAPGEF5 2 0.45 1.66 0.07
21 INT11119 Negative_regulation of Gene_expression of RAPGEF5 1 0.41 0.89 0.06
22 INT354543 Regulation of Gene_expression of RAPGEF5 1 0.03 0.82 0
23 INT188966 Regulation of Positive_regulation of RAPGEF5 1 0.36 0.38 0
24 INT279951 Negative_regulation of Negative_regulation of RAPGEF5 1 0.18 2.57 0
25 INT270739 Negative_regulation of Positive_regulation of RAPGEF5 1 0.04 0.36 0
26 INT210067 Protein_catabolism of RAPGEF5 1 0.05 0.24 0
27 INT198960 Transcription of RAPGEF5 1 0.07 1.59 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox