GO:0005096

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Name GTPase activator activity
Categary Function
Go Slim No
Go Link GO:0005096
Unique Molecular Interactions 404
Total Molecular Interactions 533
Total Single Events 2709
Pain Genes Associated 70

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for GTPase activator activity. They are ordered first by their pain relevance and then by number of times they were reported for GTPase activator activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT317526 Binding of Hint1 and Gipc1 1 0.00 0.25 2.38
2 INT54489 Binding of Jun and Rabep2 4 0.16 1.48 2.3
3 INT146099 Binding of Oprm1 and Rgs9 1 0.48 0 1.95
4 INT142899 Chn1 Negative_regulation of Positive_regulation of NOS1 1 0.01 1.07 1.75
5 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
6 INT147652 PLCB1 Negative_regulation of Positive_regulation of TRPV1 1 0.27 0.92 1.62
7 INT317558 Binding of Oprm1 and Rgs17 1 0.18 0 1.59
8 INT93781 Racgap1 Positive_regulation of Positive_regulation of Gnptab 1 0.02 0.07 1.49
9 INT93782 Racgap1 Positive_regulation of Rgs9 1 0.55 0.07 1.49
10 INT93783 Racgap1 Positive_regulation of Gnptab 1 0.02 0.07 1.49
11 INT94367 Binding of ARRB1 and TP53INP2 1 0.25 0 1.3
12 INT70288 Negative_regulation of Atxn2l Positive_regulation of Racgap1 1 0.02 0.3 1.19
13 INT146352 Binding of Rgs14 and Mors1 1 0.23 0.27 1.17
14 INT70289 Atxn2l Positive_regulation of Racgap1 1 0.04 0.29 1.15
15 INT123987 RGS17 Positive_regulation of Rgs20 1 0.13 0 1.09
16 INT54486 Npepo Positive_regulation of Gene_expression of Rabep2 1 0.14 0 1.08
17 INT146097 Positive_regulation of Binding of Rgs9 and Arrb2 1 0.28 0 1.04
18 INT146098 Binding of Rgs9 and Arrb2 1 0.19 0 1.03
19 INT221747 Gtf3a Positive_regulation of Positive_regulation of Racgap1 1 0.00 0.33 1
20 INT317550 Binding of Hint1 and Rgs20 1 0.32 0.07 0.98
21 INT354306 Binding of Rgs4 and Rgs1 1 0.40 0.36 0.98
22 INT317529 Binding of Hint1 and Rgs17 1 0.32 0.07 0.98
23 INT138072 Chn1 Positive_regulation of Oprl1 1 0.42 1.02 0.95
24 INT146096 Positive_regulation of Binding of Oprm1 and Rgs9 1 0.44 0 0.94
25 INT81329 Binding of ARRB1 and OPRK1 1 0.05 0.1 0.93
26 INT65462 Bri3 Negative_regulation of Racgap1 1 0.02 0.39 0.93
27 INT80718 Trpv3 Negative_regulation of Chn1 1 0.01 0.7 0.92
28 INT124160 Binding of Rgs9 and Mors1 1 0.23 0.28 0.9
29 INT199109 Binding of Akt1 and Arhgdia 1 0.02 2.73 0.87
30 INT125234 Positive_regulation of Binding of BCR and CD40LG 1 0.31 0.76 0.86
31 INT125233 Binding of BCR and CD40LG 1 0.23 0.75 0.85
32 INT201241 Positive_regulation of GDI2 Positive_regulation of Regulation of AGFG1 1 0.01 0 0.82
33 INT77393 Binding of ARRB1 and OPRM1 1 0.15 0 0.82
34 INT85686 Binding of Arrb1 and Arrb2 1 0.14 0.09 0.79
35 INT4915 Binding of Tac2 and Gipc1 1 0.01 0 0.74
36 INT126305 Binding of Rgs10 and Pag1 1 0.16 0.41 0.72
37 INT126306 Binding of Rgs11 and Pag1 1 0.18 0.41 0.72
38 INT126303 Binding of Rgs7 and Pag1 1 0.15 0.41 0.72
39 INT126304 Binding of Rgs2 and Pag1 1 0.16 0.41 0.72
40 INT262574 Gnaq Positive_regulation of Prkca 1 0.00 0.57 0.71
41 INT150863 Grtp1 Negative_regulation of Gpt 1 0.09 0.58 0.71
42 INT8980 Gal Regulation of PLCB1 1 0.18 0.13 0.68
43 INT94366 Binding of ARRB1 and OPRD1 1 0.11 0 0.67
44 INT281083 Binding of Gria1 and Gipc1 1 0.01 0 0.65
45 INT124158 Binding of Oprm1 and Rgs7 1 0.30 0.18 0.62
46 INT124161 Binding of Rgs7 and Rgs11 1 0.29 0.18 0.62
47 INT124159 Binding of Oprm1 and Rgs11 1 0.31 0.18 0.62
48 INT54487 Rabep2 Regulation of Gene_expression of Jun 1 0.06 0 0.61
49 INT69826 Binding of SST and TBC1D4 1 0.08 1.49 0.56
50 INT117199 Rgs1 Regulation of Rgs19 1 0.02 0.16 0.56
51 INT77394 Binding of ARRB1 and GIPC1 1 0.01 0 0.56
52 INT16643 Nppa Regulation of Rabep2 1 0.13 0.07 0.55
53 INT164973 Binding of RASA1 and Rgs7 1 0.00 0 0.54
54 INT164971 Binding of Rgs7 and Gnai2 1 0.01 0 0.54
55 INT164972 Binding of RASA1 and Rgs8 1 0.00 0 0.53
56 INT54485 Positive_regulation of Akr1d1 Positive_regulation of Gene_expression of Rabep2 1 0.00 0 0.53
57 INT164970 Binding of Rgs8 and Gnai2 1 0.01 0 0.53
58 INT330107 Racgap1 Regulation of Positive_regulation of Nox3 1 0.01 0.87 0.49
59 INT81330 ARRB1 Regulation of OPRK1 1 0.04 0.09 0.47
60 INT330108 Racgap1 Positive_regulation of Cybb 1 0.03 0.86 0.46
61 INT330110 Racgap1 Regulation of Gene_expression of Ros1 1 0.00 1.12 0.41
62 INT116678 Binding of ARRB1 and Oxtr 1 0.13 0.15 0.38
63 INT173356 Gnaq Positive_regulation of CDK20 1 0.06 0 0.37
64 INT71925 Binding of Ptprs and Positive_regulation of Racgap1 1 0.10 0 0.35
65 INT71924 Ptprs Positive_regulation of Racgap1 1 0.10 0 0.35
66 INT330106 Racgap1 Positive_regulation of Positive_regulation of Mapk8 1 0.01 1.32 0.35
67 INT109282 Gdi2 Negative_regulation of Gtpbp4 1 0.01 0.13 0.32
68 INT330109 Binding of Racgap1 and Rac1 1 0.03 1.22 0.32
69 INT191616 Binding of Cbln1 and Nf1 1 0.01 0.2 0.32
70 INT191620 Binding of Nf1 and Gopc 1 0.08 0.2 0.32
71 INT198566 Ddit4l Regulation of Axin1 1 0.03 1 0.31
72 INT316884 Positive_regulation of Binding of Cr2 and Bcr 1 0.06 0.86 0.31
73 INT316881 Positive_regulation of Binding of Cd19 and Bcr 1 0.08 0.86 0.31
74 INT191611 Nf1 Regulation of ras 1 0.26 0.18 0.3
75 INT316885 Binding of Cr2 and Bcr 1 0.06 0.85 0.3
76 INT316888 Binding of Cd19 and Bcr 1 0.08 0.85 0.3
77 INT299289 AKT1 Positive_regulation of Positive_regulation of TSC2 1 0.17 0 0.3
78 INT235957 Binding of Mog and Bcr 1 0.02 1.13 0.29
79 INT235962 Binding of Bcr and Trav6-3 1 0.00 1.12 0.29
80 INT269490 Binding of Racgap1 and HHIP 1 0.00 0 0.27
81 INT157957 Ppyr1 Negative_regulation of Phosphorylation of PLCB1 1 0.00 0.24 0.24
82 INT148574 Rgs7bp Regulation of Gene_expression of Rgs9 1 0.26 0 0.24
83 INT118857 PLCB1 Regulation of Phosphorylation of SRC 1 0.01 0.15 0.24
84 INT235972 Negative_regulation of Binding of APC and Bcr 1 0.01 1.15 0.24
85 INT235973 Binding of APC and Bcr 1 0.01 1.14 0.24
86 INT173358 Gnaq Positive_regulation of SMPD1 1 0.01 0.13 0.23
87 INT173357 Gnaq Positive_regulation of PRKCA 1 0.01 0 0.22
88 INT72019 Binding of Gnaq and Ptprg 1 0.01 0 0.21
89 INT71923 Ptprs Regulation of Racgap1 1 0.09 0 0.21
90 INT274080 Binding of ARHGAP4 and Map3k5 1 0.41 1.92 0.2
91 INT165750 Regulation of Binding of Rgs9 and Naip7 1 0.02 0.07 0.19
92 INT58588 IFNG Positive_regulation of ARHGAP4 1 0.31 1.22 0.19
93 INT231836 Pcdh8 Regulation of Positive_regulation of Racgap1 1 0.00 0.58 0.18
94 INT165752 Binding of Rgs9 and Naip7 1 0.03 0.07 0.18
95 INT231866 INCENP Regulation of Positive_regulation of Racgap1 1 0.00 0.58 0.18
96 INT103197 Nf1 Negative_regulation of ras 1 0.04 1.19 0.17
97 INT217074 Binding of Acsm3 and Axin1 1 0.00 5.37 0.17
98 INT165751 Hspa8 Positive_regulation of Protein_catabolism of Rgs9 1 0.50 0.17 0.17
99 INT191615 Binding of Nf1 and Flna 1 0.08 0.53 0.17
100 INT191621 Binding of Drd3 and Nf1 1 0.32 0.53 0.17
101 INT354823 IFNA1 Positive_regulation of Racgap1 1 0.00 1.4 0.15
102 INT234801 RAB3GAP1 Regulation of RAB3A 1 0.08 1.64 0.15
103 INT253123 Il6 Positive_regulation of Phosphorylation of Tbc1d4 1 0.38 0.63 0.15
104 INT130918 HMHA1 Positive_regulation of BAX 1 0.04 1.37 0.14
105 INT130923 HMHA1 Positive_regulation of Protein_catabolism of CASP8 1 0.04 1.37 0.14
106 INT130922 HMHA1 Positive_regulation of Protein_catabolism of CYCS 1 0.06 1.39 0.14
107 INT130917 HMHA1 Positive_regulation of CYCS 1 0.06 1.39 0.14
108 INT130921 HMHA1 Positive_regulation of CASP9 1 0.03 1.37 0.14
109 INT47351 Binding of Ralbp1 and Ccl4 1 0.11 0.17 0.14
110 INT130920 HMHA1 Positive_regulation of CASP8 1 0.04 1.36 0.14
111 INT130919 HMHA1 Positive_regulation of Protein_catabolism of CASP9 1 0.03 1.37 0.14
112 INT47352 Positive_regulation of Binding of Ralbp1 and Ccl4 1 0.14 0.17 0.14
113 INT304824 Binding of Rasa1 and Tnnc1 1 0.01 0 0.13
114 INT59808 Binding of AGT and PLCB1 1 0.02 0 0.13
115 INT59809 AGT Positive_regulation of PLCB1 1 0.03 0 0.13
116 INT59807 ADRA1D Positive_regulation of PLCB1 1 0.33 0 0.13
117 INT269491 Racgap1 Negative_regulation of RAB5A 1 0.01 0 0.12
118 INT148572 Binding of Rgs7bp and Regulation of Gene_expression of Rgs9 1 0.11 0 0.12
119 INT71301 Gdi2 Negative_regulation of Tk1 1 0.00 0.21 0.12
120 INT148573 Binding of Rgs7bp and Positive_regulation of Rgs9 1 0.21 0 0.11
121 INT74504 Binding of P2rx7 and Rp2 1 0.02 0.19 0.11
122 INT191612 Nf1 Positive_regulation of ras 1 0.25 2.6 0.11
123 INT272006 Binding of YWHAQ and Tsc2 1 0.27 0.39 0.1
124 INT249117 Binding of Abl1 and Bcr 4 0.36 2.22 0.09
125 INT228809 Gtf3a Regulation of Rgs1 1 0.00 0.25 0.09
126 INT253141 Ins1 Positive_regulation of Phosphorylation of Tbc1d4 1 0.09 0.29 0.09
127 INT228808 Smad7 Regulation of Rgs1 1 0.19 0.24 0.09
128 INT228807 Vwf Regulation of Rgs1 1 0.05 0.24 0.09
129 INT202407 Binding of Osm and Racgap1 1 0.04 0.13 0.09
130 INT202399 Binding of Mapk14 and Racgap1 1 0.07 0.13 0.09
131 INT253148 Ins1 Regulation of Phosphorylation of Tbc1d4 1 0.09 0.42 0.09
132 INT214752 EDNRA Positive_regulation of PLCB1 1 0.02 0 0.08
133 INT191617 Binding of Nf1 and Rtcd1 1 0.01 0.95 0.08
134 INT137632 Rasa1 Regulation of Ednrb 1 0.05 0 0.08
135 INT238625 Mef2c Regulation of Gene_expression of Syngap1 1 0.10 0.16 0.08
136 INT115933 U Regulation of PLCB1 1 0.00 0.3 0.08
137 INT193691 Positive_regulation of Positive_regulation of Bcr 1 0.01 0.07 0.08
138 INT193692 IgG2a Positive_regulation of Bcr 1 0.02 0.07 0.08
139 INT92273 Binding of RGS19 and GNPTAB 1 0.03 0 0.07
140 INT231863 Binding of ARHGDIA and Akt1 1 0.02 0.23 0.07
141 INT231835 Binding of Akt1 and Grlf1 1 0.01 0.35 0.07
142 INT272003 Binding of Tsc2 and Tsc1 1 0.18 1.1 0.07
143 INT227593 Gnaq Negative_regulation of GLUL 1 0.01 0 0.06
144 INT221470 Binding of Racgap1 and Camkk2 1 0.00 0.06 0.05
145 INT221469 Binding of Racgap1 and Rrad 1 0.02 0.06 0.05
146 INT325261 Ralbp1 Positive_regulation of Gene_expression of Il33 1 0.01 0 0.05
147 INT199108 Akt1 Negative_regulation of Gene_expression of Arhgdia 1 0.02 0.07 0.04
148 INT249170 Binding of AKT1 and ARHGDIA 1 0.00 0.15 0.04
149 INT231806 ARHGDIA Negative_regulation of ARHGEF1 1 0.02 0.11 0.04
150 INT246793 Binding of Tsc2 and Tsc1 1 0.04 0.71 0.04
151 INT70389 Penk Positive_regulation of Gene_expression of Rabep2 1 0.53 0 0.04
152 INT215240 Binding of Myo1f and Racgap1 1 0.01 0.77 0.04
153 INT231864 Binding of ARHGEF1 and Akt1 1 0.01 0.11 0.04
154 INT215244 Binding of Racgap1 and Mlph 1 0.04 0.76 0.04
155 INT246786 Ogg1 Regulation of Phosphorylation of Tsc2 1 0.20 0.42 0.04
156 INT231865 ARHGDIA Negative_regulation of Sergef 1 0.01 0.05 0.04
157 INT247819 Cxadr Regulation of Gene_expression of Rasa1 1 0.06 1.04 0.04
158 INT277765 Binding of BCR and Abl1 1 0.18 1.55 0.03
159 INT246791 Tsc2 Regulation of Ogg1 1 0.27 0.56 0.03
160 INT241459 Gart Positive_regulation of Racgap1 1 0.01 0 0.03
161 INT232900 Binding of ABR and Krt8 1 0.03 0.49 0.03
162 INT191613 Binding of Nf1 and Rasa1 1 0.06 0.88 0.03
163 INT183896 Gene_expression of CAV1 Negative_regulation of Positive_regulation of Racgap1 1 0.01 0.64 0.03
164 INT342733 Gene_expression of Lrrk2 Positive_regulation of Apaf1 1 0.10 0.74 0.03
165 INT295702 PTGER2 Positive_regulation of Racgap1 1 0.05 0.22 0
166 INT316500 INO80B Positive_regulation of RALBP1 1 0.00 0.31 0
167 INT295701 Positive_regulation of Binding of RAC1 and Racgap1 1 0.28 0.16 0
168 INT334471 Arhgdia Negative_regulation of Cdc42ep3 1 0.00 0 0
169 INT246784 Negative_regulation of Tsc2 Positive_regulation of Negative_regulation of Ogg1 1 0.20 0.43 0
170 INT269546 TBXA2R Regulation of ARHGEF15 1 0.00 0 0
171 INT246811 Ros1 Positive_regulation of Tsc2 1 0.02 0 0
172 INT320959 Binding of HRAS and HMHA1 1 0.00 0.37 0
173 INT262731 Binding of CHN1 and TAF1A 1 0.00 0 0
174 INT72209 BCR Positive_regulation of Mapk13 1 0.00 0 0
175 INT295704 Positive_regulation of Binding of RHOA and Racgap1 1 0.15 0.16 0
176 INT326163 Binding of Racgap1 and RAB12 1 0.00 0.68 0
177 INT246808 Tsc2 Regulation of Regulation of Tsc1 1 0.02 0.05 0
178 INT183895 CAV1 Regulation of Positive_regulation of Racgap1 1 0.01 0.37 0
179 INT246794 Ros1 Positive_regulation of Phosphorylation of Tsc2 1 0.03 0.66 0
180 INT325599 Pls1 Regulation of Rgs2 1 0.00 0 0
181 INT271990 Tsc1 Positive_regulation of Tsc2 1 0.36 0.31 0
182 INT203394 Vsnl1 Negative_regulation of Chn1 1 0.17 0.58 0
183 INT218509 Binding of BCR and Cfb 1 0.00 0.18 0
184 INT272018 Binding of TSC1 and Tsc2 1 0.17 0.48 0
185 INT251072 Wnt3a Positive_regulation of Axin2 1 0.23 0.29 0
186 INT246787 Akt2 Positive_regulation of Phosphorylation of Tsc2 1 0.10 0.16 0
187 INT232899 Krt18 Negative_regulation of Binding of ABR 1 0.05 0.68 0
188 INT225908 Binding of RAC1 and IQGAP1 1 0.00 0.09 0
189 INT246789 Pik3c3 Regulation of Tsc2 1 0.02 0.34 0
190 INT194333 Binding of MFN2 and Racgap1 1 0.01 0.38 0
191 INT338194 Regulation of VAV3 Regulation of AR 1 0.31 0.49 0
192 INT271991 Tsc1 Regulation of Tsc2 1 0.23 0.15 0
193 INT287885 Binding of DVL1 and AXIN1 1 0.02 0 0
194 INT272017 TBC1D7 Positive_regulation of Protein_catabolism of Tsc1 1 0.08 0.46 0
195 INT246809 Negative_regulation of Tsc2 Positive_regulation of Positive_regulation of Ogg1 1 0.20 0.45 0
196 INT249148 Binding of Was and Racgap1 1 0.03 0.18 0
197 INT218514 BCR Negative_regulation of Binding of Cfb 1 0.00 0.18 0
198 INT203415 Olfm1 Negative_regulation of Chn1 1 0.08 0.58 0
199 INT246801 Negative_regulation of Akt1 Negative_regulation of Phosphorylation of Tsc2 1 0.17 0 0
200 INT340379 Binding of Rabep1 and Ocrl 1 0.08 0.62 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for GTPase activator activity. They are ordered first by their pain relevance and then by number of times they were reported in GTPase activator activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT12725 Positive_regulation of Racgap1 66 0.68 32.74 19.29
2 INT111264 Gene_expression of Rgs9 16 0.76 1.96 10.94
3 INT111258 Regulation of Rgs9 11 0.54 1.81 8.9
4 INT126258 Gene_expression of Rgs17 9 0.71 0.73 8.38
5 INT60285 Negative_regulation of Racgap1 27 0.56 21.71 8.14
6 INT77404 Gene_expression of ARRB1 19 0.62 1.53 7.22
7 INT119439 Positive_regulation of Rgs7 1 0.67 2.07 7
8 INT77408 Binding of ARRB1 11 0.36 0.31 6.51
9 INT93776 Negative_regulation of Rgs9 5 0.44 0.35 5.67
10 INT72000 Gene_expression of Gnaq 17 0.75 3.12 5.48
11 INT126289 Regulation of Rgs17 3 0.41 0.89 5.47
12 INT126257 Positive_regulation of Gene_expression of Rgs17 4 0.41 0.17 4.62
13 INT116986 Gene_expression of Rgs20 4 0.77 0.69 4.45
14 INT124141 Positive_regulation of Gene_expression of Rgs9 5 0.68 0.82 3.91
15 INT138070 Gene_expression of Chn1 1 0.56 4.05 3.79
16 INT146350 Phosphorylation of Rgs14 1 0.80 0.79 3.77
17 INT130842 Gene_expression of Rgs4 5 0.78 0.59 3.76
18 INT52839 Regulation of Racgap1 14 0.25 9.46 3.37
19 INT126291 Positive_regulation of Rgs4 3 0.67 1.3 3.19
20 INT119443 Gene_expression of Rgs7 4 0.65 0.41 3.04
21 INT116985 Negative_regulation of Rgs20 1 0.43 0 3
22 INT126247 Negative_regulation of Rgs17 2 0.36 0.26 2.97
23 INT111259 Negative_regulation of Gene_expression of Rgs9 3 0.41 0.15 2.96
24 INT138068 Positive_regulation of Chn1 2 0.50 2.45 2.87
25 INT138067 Regulation of Chn1 2 0.20 2.43 2.82
26 INT93777 Negative_regulation of Rgs2 3 0.43 2.5 2.81
27 INT102763 Gene_expression of TBC1D4 3 0.03 0.81 2.76
28 INT106833 Positive_regulation of ARRB1 4 0.39 1.21 2.71
29 INT126250 Binding of Rgs17 1 0.36 0.36 2.7
30 INT211733 Phosphorylation of Gipc1 2 0.01 0 2.68
31 INT112252 Regulation of Rgs7 3 0.38 0 2.62
32 INT112253 Positive_regulation of Regulation of Rgs9 2 0.41 0.29 2.51
33 INT119435 Negative_regulation of Positive_regulation of Rgs7 1 0.42 0.77 2.51
34 INT126299 Regulation of Rgs20 3 0.41 0.89 2.5
35 INT126277 Regulation of Gene_expression of Rgs9 3 0.61 0.53 2.45
36 INT70286 Negative_regulation of Positive_regulation of Racgap1 2 0.43 3.78 2.42
37 INT142788 Transcription of Rgs19 1 0.32 0.28 2.42
38 INT61434 Regulation of Nf1 3 0.26 1.39 2.4
39 INT126249 Negative_regulation of Gene_expression of Rgs17 2 0.48 0.05 2.4
40 INT126285 Regulation of Rgs4 4 0.62 1.05 2.36
41 INT54515 Positive_regulation of Positive_regulation of Racgap1 6 0.12 2.33 2.34
42 INT70283 Gene_expression of Racgap1 19 0.44 9.64 2.33
43 INT119437 Binding of Rgs9 2 0.33 0.45 2.32
44 INT112256 Negative_regulation of Rgs11 2 0.49 0.25 2.32
45 INT126256 Positive_regulation of Rgs17 1 0.35 0 2.31
46 INT126252 Positive_regulation of Transcription of Rgs17 1 0.35 0 2.31
47 INT64700 Binding of Nf1 14 0.45 15.24 2.29
48 INT65459 Binding of Racgap1 9 0.07 4.57 2.28
49 INT59818 Negative_regulation of PLCB1 7 0.57 2.24 2.28
50 INT112255 Positive_regulation of Rgs9 2 0.54 0.35 2.26
51 INT126254 Transcription of Rgs17 1 0.40 0 2.25
52 INT77396 Regulation of ARRB1 6 0.35 2.04 2.22
53 INT70384 Positive_regulation of Rabep2 10 0.67 1.56 2.13
54 INT119450 Transcription of Rgs9 3 0.51 0.58 2.05
55 INT124145 Phosphorylation of Rgs9 2 0.72 0.29 2.05
56 INT119449 Positive_regulation of Transcription of Rgs9 1 0.37 0.54 2.02
57 INT77410 Positive_regulation of Gene_expression of ARRB1 3 0.55 0.21 1.98
58 INT119448 Transcription of Rgs7 1 0.69 0.46 1.98
59 INT112880 Positive_regulation of Gnaq 17 0.49 1.97 1.95
60 INT54477 Gene_expression of Rabep2 13 0.75 0.56 1.95
61 INT84510 Positive_regulation of Nf1 8 0.69 9.52 1.93
62 INT68181 Binding of Nf1 6 0.48 8.14 1.88
63 INT135568 Localization of CHM 5 0.65 6.51 1.76
64 INT59790 Binding of BCR 16 0.36 15.34 1.75
65 INT230668 Gene_expression of Rasa1 9 0.68 3.25 1.74
66 INT113539 Positive_regulation of Binding of ARRB1 1 0.02 0.11 1.72
67 INT142790 Gene_expression of Rgs19 1 0.30 0.18 1.67
68 INT110189 Regulation of Gnaq 3 0.02 0.26 1.63
69 INT126276 Regulation of Rgs14 1 0.39 0.71 1.63
70 INT142784 Regulation of Transcription of Rgs19 1 0.20 0.19 1.61
71 INT142898 Positive_regulation of Regulation of Chn1 1 0.25 1.02 1.57
72 INT71999 Negative_regulation of Gene_expression of Gnaq 3 0.41 0.08 1.56
73 INT112247 Positive_regulation of Regulation of Rgs7 1 0.42 0 1.52
74 INT235954 Gene_expression of Bcr 1 0.13 6.77 1.47
75 INT113659 Gene_expression of ABR 19 0.65 8.49 1.45
76 INT42391 Positive_regulation of BCR 7 0.49 4.93 1.44
77 INT109419 Regulation of Rgs7 1 0.23 0.07 1.44
78 INT109423 Regulation of Gene_expression of Rgs7 1 0.23 0.07 1.44
79 INT126298 Localization of Rgs4 2 0.78 0.67 1.4
80 INT109421 Gene_expression of Rgs7 1 0.51 0.07 1.39
81 INT126253 Positive_regulation of Binding of Rgs17 1 0.52 0.19 1.37
82 INT126251 Binding of Rgs20 1 0.07 0.19 1.37
83 INT126248 Positive_regulation of Binding of Rgs20 1 0.08 0.19 1.37
84 INT77398 Negative_regulation of ARRB1 1 0.47 0 1.31
85 INT106830 Positive_regulation of Positive_regulation of ARRB1 1 0.16 0.13 1.28
86 INT138069 Negative_regulation of Gene_expression of Chn1 1 0.31 1.38 1.28
87 INT119441 Gene_expression of Rgs11 2 0.66 0.18 1.26
88 INT131645 Negative_regulation of Nf1 10 0.58 8.12 1.24
89 INT146351 Positive_regulation of Phosphorylation of Rgs14 1 0.45 0.27 1.23
90 INT11203 Gene_expression of BCR 30 0.75 33.49 1.22
91 INT59815 Positive_regulation of PLCB1 9 0.67 1.12 1.22
92 INT110188 Regulation of Gene_expression of Gnaq 2 0.25 0.85 1.22
93 INT106832 Localization of ARRB1 2 0.22 0.3 1.21
94 INT54480 Positive_regulation of Gene_expression of Rabep2 4 0.67 0.18 1.2
95 INT138071 Regulation of Gene_expression of Chn1 1 0.20 1.31 1.2
96 INT112248 Regulation of Rgs11 2 0.24 0 1.13
97 INT77411 Regulation of Gene_expression of ARRB1 3 0.36 0.61 1.12
98 INT119447 Positive_regulation of Rgs11 1 0.42 0.35 1.08
99 INT119445 Transcription of Rgs11 1 0.45 0.35 1.08
100 INT124149 Positive_regulation of Phosphorylation of Rgs9 1 0.44 0.29 1.05
101 INT106835 Positive_regulation of Localization of ARRB1 1 0.15 0.11 1.04
102 INT211723 Binding of Rasa1 3 0.07 0.85 1.03
103 INT72002 Negative_regulation of Gnaq 7 0.35 0.2 1.02
104 INT126295 Negative_regulation of Localization of Rgs4 1 0.38 0.36 1.01
105 INT126287 Regulation of Gene_expression of Rgs17 1 0.25 0.34 0.99
106 INT17554 Regulation of ABR 6 0.54 2.21 0.98
107 INT354302 Regulation of Transcription of Rgs4 1 0.44 0.58 0.98
108 INT126279 Gene_expression of Rgs14 1 0.67 0.34 0.98
109 INT354298 Transcription of Rgs4 1 0.67 0.58 0.95
110 INT119436 Positive_regulation of Transcription of Rgs7 1 0.67 0.19 0.94
111 INT21660 Regulation of CHM 14 0.61 8.51 0.93
112 INT53710 Regulation of Negative_regulation of Arhgdia 1 0.18 0 0.92
113 INT53711 Negative_regulation of Arhgdia 1 0.28 0 0.91
114 INT84571 Gene_expression of Rgs2 6 0.67 3.18 0.89
115 INT42390 Regulation of Positive_regulation of BCR 1 0.00 0 0.87
116 INT211737 Localization of Rgs7 1 0.02 0 0.86
117 INT142791 Positive_regulation of Rgs19 1 0.21 0.1 0.86
118 INT142782 Positive_regulation of Transcription of Rgs19 1 0.21 0.1 0.86
119 INT142792 Positive_regulation of Gene_expression of Rgs19 1 0.22 0.1 0.86
120 INT142789 Regulation of Gene_expression of Rgs19 1 0.20 0.1 0.86
121 INT211730 Localization of Rgs20 1 0.55 0 0.85
122 INT211729 Localization of Rgs17 1 0.60 0 0.85
123 INT110187 Regulation of Regulation of Gnaq 1 0.00 0.07 0.82
124 INT110208 Binding of ABR 2 0.35 10.49 0.81
125 INT115757 Negative_regulation of ABR 3 0.57 0.53 0.8
126 INT124147 Positive_regulation of Binding of Rgs9 1 0.44 0.23 0.79
127 INT85678 Binding of Arrb1 1 0.20 0.09 0.78
128 INT253116 Phosphorylation of Tbc1d4 1 0.47 2.08 0.77
129 INT304823 Negative_regulation of Rasa1 6 0.10 0.39 0.76
130 INT141915 Positive_regulation of Gene_expression of Gnaq 3 0.19 1.31 0.76
131 INT70383 Negative_regulation of Positive_regulation of Rabep2 2 0.57 0.34 0.76
132 INT201253 Positive_regulation of GDI2 1 0.27 0 0.76
133 INT330076 Regulation of Positive_regulation of Racgap1 1 0.04 1.98 0.73
134 INT117195 Gene_expression of Rgs1 1 0.65 0.17 0.72
135 INT124143 Regulation of Regulation of Rgs9 1 0.24 0.25 0.72
136 INT116081 Negative_regulation of Binding of ARRB1 1 0.41 0 0.72
137 INT77406 Negative_regulation of Negative_regulation of ARRB1 1 0.47 0 0.71
138 INT77401 Regulation of Regulation of ARRB1 1 0.25 0 0.69
139 INT68179 Gene_expression of Nf1 9 0.78 8.87 0.68
140 INT179133 Localization of Nf1 2 0.80 2.18 0.68
141 INT49650 Gene_expression of Nf1 4 0.76 3.38 0.67
142 INT252054 Phosphorylation of TSC2 4 0.80 0.63 0.67
143 INT84570 Positive_regulation of Gene_expression of Rgs2 3 0.50 0.67 0.67
144 INT108772 Negative_regulation of Gdi2 1 0.08 0.42 0.67
145 INT59817 Gene_expression of PLCB1 4 0.75 0.73 0.65
146 INT119440 Binding of Rgs7 1 0.36 0 0.65
147 INT70056 Gene_expression of Chn1 3 0.32 0.47 0.63
148 INT289327 Regulation of Negative_regulation of Racgap1 2 0.05 2.09 0.62
149 INT211489 Gene_expression of ARHGAP4 6 0.65 2.88 0.61
150 INT285478 Negative_regulation of Rgs14 1 0.27 1.25 0.6
151 INT52347 Negative_regulation of CHM 17 0.58 13.03 0.59
152 INT75509 Localization of Rabep2 2 0.73 0.53 0.59
153 INT116984 Negative_regulation of Gene_expression of Rgs20 1 0.58 0 0.59
154 INT50016 Positive_regulation of ARHGAP4 3 0.49 1.8 0.58
155 INT69829 Binding of TBC1D4 1 0.07 1.49 0.56
156 INT201255 Binding of GDI2 2 0.17 0.2 0.55
157 INT112881 Positive_regulation of Positive_regulation of Gnaq 2 0.49 0.86 0.54
158 INT51236 Binding of Chn1 1 0.00 0 0.52
159 INT54479 Binding of Rabep2 1 0.09 0 0.52
160 INT273550 Positive_regulation of Bcr 14 0.68 6.71 0.49
161 INT141919 Positive_regulation of Transcription of Gnaq 1 0.21 1.05 0.49
162 INT141912 Negative_regulation of Transcription of Gnaq 1 0.18 1.07 0.49
163 INT141917 Transcription of Gnaq 1 0.29 1.05 0.49
164 INT199553 Gene_expression of Bcr 25 0.76 13.83 0.48
165 INT316933 Transcription of Nf1 1 0.18 0.49 0.47
166 INT316939 Positive_regulation of Transcription of Nf1 1 0.16 0.49 0.47
167 INT157955 Phosphorylation of PLCB1 1 0.01 0.46 0.46
168 INT210125 Regulation of Axin1 1 0.02 2.45 0.46
169 INT232886 Regulation of Gene_expression of ABR 3 0.06 1.42 0.45
170 INT126259 Regulation of RGS17 1 0.26 0 0.45
171 INT273555 Negative_regulation of Bcr 17 0.57 9.65 0.44
172 INT55893 Gene_expression of Rasa1 5 0.52 1.04 0.44
173 INT247798 Negative_regulation of Rasa1 3 0.09 1.05 0.44
174 INT199077 Localization of Racgap1 7 0.73 2.43 0.42
175 INT230653 Phosphorylation of Rasa1 3 0.55 0.6 0.42
176 INT288080 Regulation of Gene_expression of Racgap1 3 0.04 3.42 0.41
177 INT122644 Phosphorylation of Gdi2 1 0.16 0.07 0.39
178 INT60976 Positive_regulation of Gene_expression of CHN1 1 0.14 3.91 0.39
179 INT156120 Localization of Arrb1 1 0.00 0 0.38
180 INT156119 Positive_regulation of Localization of Arrb1 1 0.00 0 0.38
181 INT129343 Positive_regulation of Rasa1 2 0.10 1.03 0.37
182 INT33881 Negative_regulation of Gdi2 1 0.01 0 0.37
183 INT193674 Binding of Bcr 10 0.47 4.3 0.36
184 INT235948 Regulation of Gene_expression of Bcr 1 0.08 1.58 0.36
185 INT60977 Localization of CHN1 2 0.57 1.9 0.35
186 INT119612 Positive_regulation of Gipc1 1 0.01 0 0.35
187 INT354304 Negative_regulation of Rgs4 1 0.41 0.19 0.35
188 INT330074 Negative_regulation of Binding of Racgap1 1 0.03 1.47 0.35
189 INT74604 Negative_regulation of Gene_expression of PLCB1 1 0.41 0.25 0.35
190 INT354292 Regulation of Regulation of Rgs4 1 0.44 0.14 0.34
191 INT354300 Positive_regulation of Regulation of Rgs4 1 0.45 0.14 0.34
192 INT221833 Positive_regulation of TSC2 2 0.23 0.39 0.33
193 INT330075 Negative_regulation of Transcription of Racgap1 1 0.03 1.05 0.33
194 INT330077 Transcription of Racgap1 1 0.05 1.04 0.33
195 INT50014 Negative_regulation of ARHGAP4 2 0.27 1.59 0.32
196 INT59816 Positive_regulation of Gene_expression of PLCB1 2 0.49 0.22 0.31
197 INT270418 Negative_regulation of Negative_regulation of Racgap1 1 0.02 0.53 0.31
198 INT199557 Positive_regulation of Gene_expression of Bcr 6 0.68 4.21 0.3
199 INT148570 Protein_catabolism of Rgs9 1 0.98 0.17 0.3
200 INT129166 Positive_regulation of Bcr 2 0.28 1.18 0.29
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