GO:0005099

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Name Ras GTPase activator activity
Categary Function
Go Slim No
Go Link GO:0005099
Unique Molecular Interactions 54
Total Molecular Interactions 91
Total Single Events 473
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for Ras GTPase activator activity. They are ordered first by their pain relevance and then by number of times they were reported for Ras GTPase activator activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
2 INT74395 Htr2b Negative_regulation of Pdyn 1 0.03 0 0.61
3 INT144864 Htr2b Positive_regulation of Localization of Gh1 1 0.48 0 0.58
4 INT164973 Binding of RASA1 and Rgs7 1 0.00 0 0.54
5 INT164972 Binding of RASA1 and Rgs8 1 0.00 0 0.53
6 INT191616 Binding of Cbln1 and Nf1 1 0.01 0.2 0.32
7 INT191620 Binding of Nf1 and Gopc 1 0.08 0.2 0.32
8 INT191611 Nf1 Regulation of ras 1 0.26 0.18 0.3
9 INT229635 SPINK5 Positive_regulation of NF1 1 0.01 2.17 0.3
10 INT103197 Nf1 Negative_regulation of ras 1 0.04 1.19 0.17
11 INT191615 Binding of Nf1 and Flna 1 0.08 0.53 0.17
12 INT191621 Binding of Drd3 and Nf1 1 0.32 0.53 0.17
13 INT103198 NF1 Negative_regulation of ras 1 0.05 1.19 0.16
14 INT304824 Binding of Rasa1 and Tnnc1 1 0.01 0 0.13
15 INT191612 Nf1 Positive_regulation of ras 1 0.25 2.6 0.11
16 INT191617 Binding of Nf1 and Rtcd1 1 0.01 0.95 0.08
17 INT137632 Rasa1 Regulation of Ednrb 1 0.05 0 0.08
18 INT206849 ESR1 Regulation of Gene_expression of ALDH1A1 1 0.11 2.26 0.04
19 INT247819 Cxadr Regulation of Gene_expression of Rasa1 1 0.06 1.04 0.04
20 INT191613 Binding of Nf1 and Rasa1 1 0.06 0.88 0.03
21 INT233506 Tlr4 Positive_regulation of Htr2b 1 0.06 0.09 0
22 INT291753 ALDOA Positive_regulation of ALDH1A1 1 0.00 0 0
23 INT225892 Binding of GAB1 and RASA1 1 0.01 0.06 0
24 INT331235 RASA1 Positive_regulation of Mtor 1 0.00 0.32 0
25 INT225908 Binding of RAC1 and IQGAP1 1 0.00 0.09 0
26 INT271966 Phosphorylation of Rasa1 Positive_regulation of Tsc2 1 0.01 0.31 0
27 INT293795 Binding of RASA1 and ras 1 0.00 0.08 0
28 INT206843 Binding of ALDH1A1 and ESR1 1 0.07 0 0
29 INT331229 Rasa1 Positive_regulation of Mtor 1 0.00 0.32 0
30 INT331233 Binding of Mtor and Rasa1 1 0.00 0.32 0
31 INT331236 Binding of RASA1 and Mtor 1 0.00 0.32 0
32 INT180836 Binding of CTD and NF1 1 0.15 0.2 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for Ras GTPase activator activity. They are ordered first by their pain relevance and then by number of times they were reported in Ras GTPase activator activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT68216 Binding of NF1 40 0.48 51.24 4.59
2 INT28983 Regulation of Htr2b 3 0.22 0.26 3.96
3 INT17993 Negative_regulation of RASA1 8 0.41 7.34 2.62
4 INT61434 Regulation of Nf1 3 0.26 1.39 2.4
5 INT64700 Binding of Nf1 14 0.45 15.24 2.29
6 INT43900 Gene_expression of RASA1 13 0.58 12 2.03
7 INT84510 Positive_regulation of Nf1 8 0.69 9.52 1.93
8 INT68181 Binding of Nf1 6 0.48 8.14 1.88
9 INT230668 Gene_expression of Rasa1 9 0.68 3.25 1.74
10 INT161217 Positive_regulation of Htr2b 1 0.67 2.55 1.58
11 INT14916 Binding of RASA1 15 0.37 13.64 1.44
12 INT131645 Negative_regulation of Nf1 10 0.58 8.12 1.24
13 INT61993 Gene_expression of NF1 29 0.78 34.47 1.23
14 INT161216 Positive_regulation of Gene_expression of Htr2b 1 0.49 1.87 1.16
15 INT161219 Gene_expression of Htr2b 4 0.75 2.01 1.14
16 INT211723 Binding of Rasa1 3 0.07 0.85 1.03
17 INT30157 Gene_expression of Htr2b 2 0.48 0 0.94
18 INT304823 Negative_regulation of Rasa1 6 0.10 0.39 0.76
19 INT68179 Gene_expression of Nf1 9 0.78 8.87 0.68
20 INT179133 Localization of Nf1 2 0.80 2.18 0.68
21 INT49650 Gene_expression of Nf1 4 0.76 3.38 0.67
22 INT57127 Binding of Htr2b 2 0.36 0.05 0.63
23 INT90416 Positive_regulation of RASA1 3 0.67 1.58 0.56
24 INT61992 Positive_regulation of Gene_expression of NF1 3 0.50 4.47 0.51
25 INT7248 Localization of RASA1 4 0.61 2.52 0.47
26 INT316933 Transcription of Nf1 1 0.18 0.49 0.47
27 INT316939 Positive_regulation of Transcription of Nf1 1 0.16 0.49 0.47
28 INT206880 Gene_expression of ALDH1A1 5 0.45 5.02 0.45
29 INT55893 Gene_expression of Rasa1 5 0.52 1.04 0.44
30 INT247798 Negative_regulation of Rasa1 3 0.09 1.05 0.44
31 INT161218 Positive_regulation of Positive_regulation of Htr2b 1 0.67 0.69 0.43
32 INT230653 Phosphorylation of Rasa1 3 0.55 0.6 0.42
33 INT76874 Negative_regulation of Htr2b 1 0.07 0 0.41
34 INT129343 Positive_regulation of Rasa1 2 0.10 1.03 0.37
35 INT112334 Regulation of NF1 18 0.52 15.85 0.34
36 INT55894 Positive_regulation of Gene_expression of Rasa1 1 0.47 0.19 0.28
37 INT57126 Transcription of Htr2b 1 0.33 0 0.24
38 INT129342 Positive_regulation of Positive_regulation of Nf1 1 0.50 0.79 0.23
39 INT68180 Regulation of Nf1 2 0.27 2.02 0.22
40 INT177938 Negative_regulation of NF1 9 0.43 10.3 0.2
41 INT129341 Negative_regulation of Gene_expression of Nf1 2 0.43 1.67 0.2
42 INT155285 Positive_regulation of Nf1 1 0.16 0.55 0.17
43 INT201013 Regulation of Gene_expression of RASA1 1 0.05 0.16 0.16
44 INT103196 Negative_regulation of Gene_expression of Nf1 1 0.57 1.21 0.16
45 INT55892 Negative_regulation of Gene_expression of Rasa1 1 0.29 0.1 0.15
46 INT304822 Regulation of Negative_regulation of Rasa1 1 0.05 0 0.14
47 INT304820 Transcription of Rasa1 1 0.10 0 0.12
48 INT201009 Transcription of RASA1 1 0.07 0.14 0.12
49 INT349974 Positive_regulation of Rasa1 1 0.04 0.92 0.11
50 INT61991 Negative_regulation of Gene_expression of NF1 1 0.59 1.67 0.08
51 INT190026 Positive_regulation of Gene_expression of Nf1 3 0.53 2.45 0.07
52 INT247808 Negative_regulation of Localization of Rasa1 1 0.06 0.96 0.04
53 INT247815 Localization of Rasa1 1 0.10 1.69 0.04
54 INT206879 Positive_regulation of Gene_expression of ALDH1A1 1 0.25 1.32 0.03
55 INT206871 Regulation of Gene_expression of ALDH1A1 1 0.23 1.32 0.03
56 INT206873 Negative_regulation of Gene_expression of ALDH1A1 1 0.34 1.3 0.03
57 INT169558 Positive_regulation of NF1 13 0.59 13.58 0
58 INT112333 Localization of NF1 2 0.51 0.63 0
59 INT216268 Positive_regulation of Positive_regulation of NF1 2 0.40 2.08 0
60 INT225851 Phosphorylation of RASA1 2 0.05 0.14 0
61 INT233451 Negative_regulation of Htr2b 1 0.33 0.09 0
62 INT230655 Regulation of Gene_expression of Rasa1 1 0.54 0.26 0
63 INT247790 Regulation of Rasa1 1 0.05 1.44 0
64 INT230656 Positive_regulation of Gene_expression of Rasa1 1 0.61 0.24 0
65 INT291974 Regulation of RASA1 1 0.03 0.29 0
66 INT346853 Binding of Rasa1 1 0.09 1.24 0
67 INT286141 Negative_regulation of Negative_regulation of NF1 1 0.01 0.66 0
68 INT237279 Regulation of Binding of NF1 1 0.38 0.79 0
69 INT347593 Negative_regulation of Gene_expression of Htr2b 1 0.01 0.16 0
70 INT177934 Regulation of Gene_expression of NF1 1 0.19 1.23 0
71 INT335031 Positive_regulation of Gene_expression of RASA1 1 0.09 1.49 0
72 INT225855 Binding of IQGAP1 1 0.02 0.09 0
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