GO:0005102

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Name receptor binding
Categary Function
Go Slim No
Go Link GO:0005102
Unique Molecular Interactions 6275
Total Molecular Interactions 9288
Total Single Events 83637
Pain Genes Associated 330

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for receptor binding. They are ordered first by their pain relevance and then by number of times they were reported for receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69872 Binding of MC1R and POMC 52 0.54 8.87 18.3
2 INT6078 Pomc Positive_regulation of Localization of Penk 13 0.51 0 15.49
3 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
4 INT166591 Binding of CALCA and DCLK3 4 0.30 0.69 12.18
5 INT10268 Binding of PDYN and POMC 11 0.39 0.08 10.36
6 INT6079 Pomc Positive_regulation of Penk 9 0.43 0 9.46
7 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26
8 INT2714 Pomc Positive_regulation of Localization of Prl 17 0.79 0.5 8.18
9 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
10 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33
11 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
12 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49
13 INT91538 Pomc Positive_regulation of P9Ehs1 6 0.11 1.47 6.23
14 INT176477 Binding of CXCR3 and CXCL10 14 0.25 10.61 5.87
15 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
16 INT79759 Ngf Regulation of Il6 1 0.60 4.62 5.62
17 INT296275 Binding of Dlg4 and Kcnip3 1 0.39 3.58 5.6
18 INT92466 Pomc Positive_regulation of Binding of Crygs 8 0.06 0 5.56
19 INT227157 Binding of PEBP1 and Gpm6a 1 0.00 1.28 5.52
20 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23
21 INT15842 Crh Positive_regulation of Localization of Pomc 15 0.73 5 5.05
22 INT1310 Pomc Regulation of Localization of Prl 9 0.40 0.61 4.96
23 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
24 INT102122 Binding of Calca and RT1-M4 7 0.29 5.83 4.94
25 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
26 INT29206 Crh Regulation of Localization of POMC 4 0.64 0.96 4.68
27 INT24742 Binding of Calca and Vip 1 0.37 0.18 4.68
28 INT32444 Binding of Cpe and Pomc 2 0.22 0 4.47
29 INT111758 Binding of Drd2 and Insrr 1 0.01 0.94 4.33
30 INT113223 POMC Regulation of MC1R 6 0.68 0.39 4.24
31 INT1313 Pomc Positive_regulation of Prl 7 0.35 0 4.19
32 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15
33 INT29240 Binding of POMC and YY1 5 0.40 0.17 4.06
34 INT34220 Binding of POMC and Oprl1 4 0.01 0.25 4.05
35 INT13969 Binding of Calca and Sst 3 0.32 0.6 4.02
36 INT73539 Binding of Ngf and Ngfr 5 0.45 3.99 4
37 INT20456 Binding of Pomc and Penk 9 0.41 0.26 3.93
38 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91
39 INT143946 Binding of Pebp1 and Mastl 1 0.00 2.04 3.82
40 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
41 INT71069 Oprl1 Regulation of Gene_expression of Tac4 1 0.03 0.13 3.64
42 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
43 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52
44 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
45 INT24710 Binding of Calca and SUB1P1 1 0.01 2.09 3.48
46 INT108473 Binding of ADCYAP1 and PNOC 1 0.32 0.64 3.41
47 INT152035 Binding of HLA-A and MRAP 2 0.31 6.95 3.4
48 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35
49 INT7436 CFP Positive_regulation of Binding of POMC 1 0.02 0.18 3.35
50 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
51 INT182704 Binding of NPFF and TP53INP2 1 0.01 0.73 3.28
52 INT108471 Binding of CALCA and PNOC 1 0.29 0.64 3.25
53 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
54 INT3434 Vip Positive_regulation of Localization of Prl 6 0.76 0.16 3.21
55 INT18793 Crh Regulation of Localization of Penk 1 0.59 0 3.2
56 INT270949 Binding of Slc6a3 and Cpe 1 0.28 0.25 3.19
57 INT34294 Penk Positive_regulation of Localization of Crh 1 0.16 0.43 3.19
58 INT91271 Mtr Regulation of Gene_expression of Il6 1 0.20 0 3.17
59 INT149492 PNOC Negative_regulation of Gene_expression of CCL2 1 0.15 0.68 3.17
60 INT29657 Binding of Calca and Calcb 1 0.26 0 3.16
61 INT251146 Binding of Grin1 and Dlg2 1 0.36 1.95 3.16
62 INT17456 Binding of CSF2 and POMC 3 0.32 4.06 3.15
63 INT6076 Negative_regulation of Pomc Positive_regulation of Penk 3 0.31 0 3.14
64 INT211694 Binding of Cntnap1 and Nav1 1 0.04 0 3.14
65 INT81708 POMC Regulation of Gene_expression of ITGAM 1 0.53 0.72 3.1
66 INT101408 Binding of Grin1 and Olr1469 1 0.03 0.86 3.1
67 INT101407 Binding of Grin1 and Spr 1 0.14 0.86 3.09
68 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
69 INT106837 Binding of Oprm1 and Arrb2 3 0.32 0.83 3.01
70 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
71 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
72 INT100835 Binding of Calca and Akap12 1 0.07 0.41 2.92
73 INT166592 Binding of CALCA and RAMP1 2 0.35 0.33 2.91
74 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
75 INT134212 CRH Regulation of Localization of POMC 1 0.47 2.89 2.9
76 INT156381 Binding of Grin1 and Dlg4 1 0.39 0.86 2.9
77 INT111757 Positive_regulation of Binding of Drd2 and Insrr 1 0.02 0.64 2.89
78 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84
79 INT194409 Binding of CALCA and IGKV1D-8 1 0.15 0 2.84
80 INT32656 Pomc Positive_regulation of Rbm39 1 0.08 0.42 2.84
81 INT107723 POMC Positive_regulation of MC1R 7 0.68 0.71 2.82
82 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79
83 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
84 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79
85 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78
86 INT91649 Binding of Lbp and SPECC1 1 0.12 2.88 2.78
87 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
88 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
89 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
90 INT69057 H2-M3 Regulation of Klkb1 1 0.00 0.42 2.71
91 INT326585 Binding of GYPA and SLC6A3 1 0.13 0.86 2.64
92 INT351444 Grin1 Positive_regulation of Gria2 1 0.22 1.5 2.64
93 INT62450 Il2 Positive_regulation of Localization of Crh 1 0.43 0.59 2.64
94 INT212505 Binding of pr and Lbp 1 0.01 4.26 2.62
95 INT30345 Pomc Regulation of Localization of Penk 3 0.31 0 2.61
96 INT53648 Acot1 Positive_regulation of Localization of Calca 2 0.23 0 2.61
97 INT29446 Crh Positive_regulation of Localization of POMC 8 0.38 1.87 2.58
98 INT340117 Binding of Bdnf and Pain1 1 0.01 2.48 2.55
99 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
100 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
101 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
102 INT107812 Nppa Positive_regulation of Localization of Sst 1 0.48 0.54 2.51
103 INT48526 Binding of Calca and Penk 1 0.24 1.03 2.51
104 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
105 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5
106 INT317528 Ppp1r9b Regulation of Grin1 1 0.18 0.2 2.48
107 INT21520 Crh Regulation of Pomc 3 0.22 0.4 2.45
108 INT251147 Binding of Grin2b and Dlg2 1 0.33 2.75 2.43
109 INT56726 Cpe Negative_regulation of Pomc 1 0.07 0 2.41
110 INT136129 Calca Positive_regulation of ATP8A2 1 0.38 0.89 2.4
111 INT318998 IFNA1 Positive_regulation of Localization of CXCL10 1 0.15 2.09 2.39
112 INT214144 Cck Positive_regulation of Pomc 1 0.15 0.94 2.39
113 INT317526 Binding of Hint1 and Gipc1 1 0.00 0.25 2.38
114 INT107578 Kitl Negative_regulation of Grin2b 1 0.12 2.05 2.36
115 INT29716 Crh Negative_regulation of Localization of Gnrh1 5 0.44 0 2.35
116 INT314205 Ngf Positive_regulation of Phosphorylation of Mapk14 1 0.43 1.24 2.3
117 INT13967 Calca Positive_regulation of Sst 1 0.45 0 2.3
118 INT152900 TRPV1 Regulation of Gene_expression of CALCA 1 0.69 0.73 2.29
119 INT152901 TRPV1 Regulation of Localization of CALCA 1 0.44 0.73 2.29
120 INT228454 Ngf Positive_regulation of Phosphorylation of Trpv1 1 0.39 2.97 2.26
121 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
122 INT51317 Binding of POMC and OR5D2P 1 0.00 0.6 2.23
123 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
124 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
125 INT34310 CRH Positive_regulation of POMC 3 0.42 0.62 2.21
126 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21
127 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
128 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
129 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
130 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
131 INT32586 H2-Ab1 Regulation of Pomc 1 0.03 0.14 2.19
132 INT1315 Pomc Positive_regulation of Localization of Gnrhr 3 0.38 0.16 2.16
133 INT49242 Binding of Mc1r and Pomc 10 0.38 3.79 2.15
134 INT18791 Crh Regulation of Penk 2 0.49 0 2.15
135 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
136 INT239037 Binding of Cd28 and Cd86 9 0.16 3.69 2.14
137 INT229394 TPSD1 Positive_regulation of F2RL1 2 0.00 3.11 2.14
138 INT319581 Binding of PIAS1 and TNFSF14 1 0.02 1.58 2.13
139 INT344386 Efnb1 Positive_regulation of Phosphorylation of Ephb2 1 0.15 2.85 2.13
140 INT240131 Binding of Crp and Nppb 7 0.07 11.53 2.12
141 INT351380 Ngf Regulation of TPM1 1 0.44 2.17 2.11
142 INT356313 Crh Positive_regulation of Localization of Helt 1 0.02 0 2.11
143 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
144 INT79470 Mgat4a Regulation of Localization of Calca 1 0.08 1.72 2.1
145 INT89733 Binding of Calca and Nrm 1 0.31 0.71 2.09
146 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
147 INT28387 Pomc Positive_regulation of Localization of LH 2 0.40 0.28 2.07
148 INT30954 Crh Negative_regulation of LH 5 0.46 1.4 2.06
149 INT134215 CRH Positive_regulation of ENG 1 0.13 1.22 2.06
150 INT63873 SRPX Positive_regulation of Localization of Calca 1 0.02 0.49 2.04
151 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
152 INT26221 Calca Regulation of Gt(pU21)50Imeg 1 0.01 0 2.02
153 INT138962 Dbi Positive_regulation of Pomc 1 0.00 1.53 2
154 INT32585 H2-Ab1 Negative_regulation of Pomc 1 0.03 0.13 2
155 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
156 INT60626 Crh Positive_regulation of Localization of Pomc 7 0.54 2.3 1.99
157 INT26948 Pomc Positive_regulation of Localization of Gh1 2 0.22 0.15 1.99
158 INT274372 Phc1 Negative_regulation of Slc6a3 1 0.06 0.47 1.99
159 INT213968 Binding of Calca and Mthfd1 1 0.05 0.16 1.99
160 INT163266 Crh Negative_regulation of Tyr 1 0.01 0.45 1.98
161 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
162 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
163 INT264947 Binding of POMC and TLR2 1 0.03 0.89 1.95
164 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
165 INT165284 Positive_regulation of Nts Positive_regulation of Crh 1 0.40 1.86 1.93
166 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
167 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91
168 INT165285 Nts Positive_regulation of Crh 1 0.40 1.84 1.91
169 INT149469 Oxt Regulation of Gene_expression of Crh 1 0.45 1.2 1.91
170 INT93293 Ngf Regulation of Trpv1 2 0.28 0.71 1.9
171 INT91607 Binding of EDN1 and POMC 1 0.12 0 1.9
172 INT31438 Penk Positive_regulation of Localization of Pomc 1 0.18 0 1.9
173 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
174 INT166945 Ngf Positive_regulation of Trpv1 1 0.01 0.47 1.88
175 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
176 INT201940 Binding of IL8 and CXCL10 2 0.28 2.46 1.86
177 INT166947 Ngf Positive_regulation of KNG1 1 0.00 0.47 1.86
178 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
179 INT314210 Ngf Regulation of Phosphorylation of Mapk14 1 0.34 0.85 1.84
180 INT169468 Binding of Egfr and Spink3 1 0.37 3.73 1.83
181 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82
182 INT19496 Pomc Regulation of Localization of Ins1 1 0.55 0.33 1.82
183 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
184 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 0.30 1.36 1.8
185 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
186 INT334345 Binding of GRP and Helt 1 0.02 0 1.79
187 INT29715 Crh Negative_regulation of Localization of LH 5 0.43 0 1.78
188 INT203149 Binding of Mif and Osm 1 0.02 2.93 1.78
189 INT14576 Tac4 Regulation of Penk 1 0.07 0 1.77
190 INT336556 SLC6A3 Positive_regulation of Gene_expression of GOPC 1 0.08 1.87 1.76
191 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75
192 INT24934 Calca Regulation of Nka1 3 0.05 0.43 1.73
193 INT26676 Pomc Regulation of Localization of Trh 3 0.14 0 1.73
194 INT165183 Ifnb1 Positive_regulation of P2rx4 1 0.04 1.73 1.73
195 INT185143 Elane Positive_regulation of Pik3r1 1 0.01 0 1.72
196 INT6407 Binding of Lama5 and Oprm1 1 0.02 0.08 1.72
197 INT24817 Binding of POMC and VTN 8 0.42 0.39 1.71
198 INT68709 Positive_regulation of Crh Regulation of Npr1 1 0.03 0 1.71
199 INT148090 Binding of CALCA and NCOR2 1 0.00 0.65 1.71
200 INT296280 Binding of Car2 and Dlg4 1 0.19 0.45 1.71

Single Events

The table below shows the top 100 pain related interactions that have been reported for receptor binding. They are ordered first by their pain relevance and then by number of times they were reported in receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 2008 0.81 518.3 1408.65
2 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84
3 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08
4 INT443 Localization of POMC 1020 0.81 284.52 443.17
5 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04
6 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16
7 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38
8 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83
9 INT2649 Regulation of Calca 433 0.62 146.05 330.95
10 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98
11 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57
12 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
13 INT738 Regulation of POMC 459 0.62 111.19 243.74
14 INT1562 Localization of Crh 499 0.81 126.74 236.68
15 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45
16 INT626 Localization of CALCA 289 0.81 125.39 221.15
17 INT1308 Localization of Pomc 457 0.81 66.83 217.5
18 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24
19 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
20 INT1652 Regulation of Pomc 387 0.62 61.01 186.51
21 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71
22 INT438 Gene_expression of Crh 376 0.78 159.11 169.17
23 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77
24 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02
25 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63
26 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37
27 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61
28 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57
29 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2
30 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24
31 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47
32 INT2541 Binding of Calca 200 0.48 67.14 134.62
33 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14
34 INT1878 Binding of HLA-B 440 0.48 321.16 127.36
35 INT695 Binding of POMC 304 0.48 56.66 126.85
36 INT5008 Localization of Calca 204 0.81 80.35 125.16
37 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64
38 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28
39 INT1026 Binding of Lbp 207 0.48 150.96 119.16
40 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75
41 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38
42 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68
43 INT1438 Localization of Pomc 360 0.81 101.26 116.47
44 INT9012 Localization of Vip 283 0.81 31.71 106.16
45 INT1898 Regulation of Crh 220 0.62 61.33 102.64
46 INT65500 Gene_expression of App 605 0.78 429.94 98.31
47 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61
48 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48
49 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84
50 INT214 Localization of AVP 370 0.81 208.51 91.09
51 INT1635 Gene_expression of Vip 245 0.78 53.36 88.13
52 INT21793 Positive_regulation of Ngf 154 0.70 94.78 85.27
53 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03
54 INT5617 Localization of Nppa 266 0.81 83.51 83.89
55 INT92518 Gene_expression of Grin2b 131 0.78 65.52 80.91
56 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37
57 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42
58 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66
59 INT7134 Localization of KNG1 127 0.79 65.73 67.97
60 INT19511 Localization of Il6 212 0.81 118.17 67.67
61 INT8388 Positive_regulation of Vip 142 0.70 39.72 67.61
62 INT462 Regulation of Pomc 157 0.62 41.67 67.27
63 INT11937 Localization of Il6 228 0.81 139.83 64.39
64 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6
65 INT9664 Binding of LBP 127 0.48 94.9 63.42
66 INT46 Localization of Ren 233 0.81 46.15 62.44
67 INT10706 Regulation of Il6 150 0.62 93.23 62.34
68 INT6761 Binding of CALCA 100 0.48 26.71 62.05
69 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85
70 INT1437 Negative_regulation of Pomc 132 0.59 35.22 60.97
71 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3
72 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28
73 INT90911 Positive_regulation of Phosphorylation of Grin1 62 0.70 27.45 59.26
74 INT11491 Positive_regulation of KNG1 128 0.67 60.41 58.74
75 INT1307 Positive_regulation of Localization of Pomc 120 0.70 24.58 58.48
76 INT7340 Regulation of Grin1 87 0.62 30.37 57.93
77 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74
78 INT5453 Regulation of Localization of POMC 114 0.62 20.56 56.34
79 INT1463 Binding of Pomc 129 0.48 15.89 56.27
80 INT314 Positive_regulation of Ren 212 0.70 66.68 55.56
81 INT4241 Regulation of CALCA 87 0.62 28.19 55.29
82 INT5506 Positive_regulation of Gene_expression of Pomc 132 0.70 26.78 54.3
83 INT1027 Gene_expression of Lbp 132 0.77 106.7 54.16
84 INT5509 Positive_regulation of Localization of Crh 91 0.70 30.65 53.92
85 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
86 INT4891 Transcription of Calca 81 0.72 35.27 53.75
87 INT7898 Gene_expression of Homer1 123 0.78 31.52 53.67
88 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66
89 INT4957 Negative_regulation of Grin1 87 0.59 24.51 53.21
90 INT5623 Positive_regulation of Nppa 174 0.70 69.96 52.33
91 INT27954 Positive_regulation of Gene_expression of Ngf 87 0.70 57.91 51.96
92 INT66040 Positive_regulation of Bdnf 114 0.69 67.67 51.81
93 INT97674 Positive_regulation of Localization of Calca 70 0.69 27.71 51.79
94 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34
95 INT1197 Negative_regulation of Localization of POMC 109 0.59 28.29 48.02
96 INT654 Localization of REN 250 0.81 75.12 47.86
97 INT375 Positive_regulation of REN 293 0.70 152.46 47.55
98 INT57021 Positive_regulation of Gene_expression of Grin1 62 0.70 24.77 47.31
99 INT683 Positive_regulation of AVP 173 0.70 74.55 46.41
100 INT1028 Positive_regulation of Lbp 102 0.69 67.86 46.05
101 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22
102 INT8824 Regulation of Vip 95 0.62 15.7 43.63
103 INT1295 Binding of Pomc 85 0.48 12.92 42.8
104 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8
105 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
106 INT94029 Positive_regulation of Grin2b 58 0.70 24.2 42.52
107 INT5502 Positive_regulation of Gene_expression of Crh 69 0.70 43.06 42.23
108 INT9372 Negative_regulation of Lbp 86 0.58 46.54 41.71
109 INT5454 Localization of CRH 124 0.79 79.18 41.53
110 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24
111 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17
112 INT4887 Gene_expression of Tac4 70 0.77 11.66 40.97
113 INT685 Regulation of AVP 124 0.62 34.9 39.91
114 INT92517 Gene_expression of Grin1 105 0.78 29.53 39.43
115 INT2782 Regulation of Gene_expression of Pomc 75 0.62 15.04 38.97
116 INT1931 Positive_regulation of Gene_expression of POMC 116 0.70 37.26 38.67
117 INT20210 Localization of Ngf 69 0.79 46.22 38.57
118 INT16455 Gene_expression of Drd2 116 0.78 22.71 38.47
119 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14
120 INT81037 Negative_regulation of Slc6a3 70 0.59 15.31 37.01
121 INT11246 Binding of Grin1 65 0.48 14.53 36.93
122 INT5620 Positive_regulation of Localization of Nppa 105 0.70 30.23 36.45
123 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08
124 INT49 Negative_regulation of Ren 129 0.59 37.48 35.62
125 INT13501 Binding of Drd2 65 0.48 23.76 35.6
126 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23
127 INT100733 Positive_regulation of F2RL1 62 0.70 59.14 35.22
128 INT130479 Phosphorylation of Grin2b 28 0.77 34.82 34.97
129 INT52194 Positive_regulation of Grin1 83 0.69 25.09 34.76
130 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
131 INT8784 Negative_regulation of Positive_regulation of Calca 40 0.59 14.67 33.49
132 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45
133 INT1116 Regulation of Ren 103 0.62 27.66 33.26
134 INT19759 Gene_expression of LBP 77 0.77 56.44 33.23
135 INT65698 Localization of CCL2 118 0.81 77.54 32.69
136 INT57024 Regulation of Gene_expression of Grin1 32 0.62 9.77 32.6
137 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58
138 INT6683 Gene_expression of Drd2 64 0.78 11.31 32.28
139 INT14497 Gene_expression of GRP 82 0.78 17.67 32.27
140 INT9655 Regulation of Il6 98 0.62 70.92 31.95
141 INT93451 Positive_regulation of Gene_expression of Grin2b 43 0.70 29.09 31.89
142 INT7082 Gene_expression of CRH 180 0.78 64.66 31.74
143 INT11087 Positive_regulation of Drd2 54 0.69 12.4 31.43
144 INT29743 Negative_regulation of App 91 0.59 65.56 31.26
145 INT608 Negative_regulation of KNG1 98 0.43 72.36 31.23
146 INT6277 Positive_regulation of Gene_expression of Pomc 76 0.70 21.45 31.09
147 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
148 INT15347 Positive_regulation of Localization of Pomc 81 0.70 28.1 31.01
149 INT106554 Positive_regulation of Gene_expression of Bdnf 73 0.70 42.58 30.77
150 INT5505 Regulation of Localization of Pomc 54 0.61 6.96 30.77
151 INT5507 Regulation of Localization of Crh 57 0.61 8.43 30.26
152 INT50 Negative_regulation of Localization of Ren 87 0.59 14.94 30.22
153 INT6196 Regulation of Nppa 83 0.62 30.31 30.18
154 INT660 Negative_regulation of REN 194 0.59 82.06 29.46
155 INT5514 Negative_regulation of Localization of Crh 64 0.58 8.12 29.29
156 INT106540 Negative_regulation of Phosphorylation of Grin1 15 0.58 9.32 29.13
157 INT47712 Positive_regulation of App 135 0.69 101.38 28.94
158 INT102206 Regulation of Bdnf 37 0.62 28.54 28.78
159 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76
160 INT1196 Positive_regulation of Positive_regulation of POMC 51 0.70 15.99 28.58
161 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54
162 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43
163 INT16879 Binding of Crh 72 0.48 21.65 28.43
164 INT116737 Localization of Mif 63 0.81 52.97 28.11
165 INT4861 Localization of GRP 84 0.80 8.26 28.03
166 INT22499 Regulation of Calca 42 0.62 17.32 28.02
167 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97
168 INT21379 Transcription of Crh 65 0.72 15.64 27.92
169 INT3076 Regulation of KNG1 52 0.60 20.39 27.89
170 INT6174 Regulation of Gene_expression of POMC 49 0.61 9.75 27.69
171 INT7565 Transcription of Pomc 69 0.72 14.46 27.41
172 INT5604 Positive_regulation of Drd2 47 0.67 10.75 27.41
173 INT7894 Negative_regulation of Vip 59 0.59 11.76 27.36
174 INT5206 Gene_expression of AR 316 0.78 113.83 27.29
175 INT80470 Negative_regulation of Gene_expression of Grin1 33 0.59 10.22 27.15
176 INT56053 Negative_regulation of Bdnf 77 0.58 64.4 26.83
177 INT3167 Binding of KNG1 48 0.48 23.26 26.77
178 INT78251 Positive_regulation of LBP 38 0.69 39.98 26.73
179 INT93360 Gene_expression of Slc6a3 63 0.78 19.54 26.55
180 INT7899 Positive_regulation of Gene_expression of Homer1 41 0.70 7.29 25.98
181 INT9088 Negative_regulation of LBP 48 0.58 33.06 25.89
182 INT63769 Regulation of Ngf 44 0.62 21.82 25.84
183 INT80791 Gene_expression of Slc6a3 113 0.78 11.89 25.76
184 INT8205 Negative_regulation of Nppa 77 0.59 26.43 25.72
185 INT86789 Gene_expression of P2rx4 46 0.77 30.66 25.68
186 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62
187 INT7584 Gene_expression of Crh 112 0.78 39.15 25.33
188 INT5622 Gene_expression of Nppa 101 0.78 49.46 25.31
189 INT17625 Localization of GCG 210 0.80 55.69 24.97
190 INT1030 Localization of Lbp 52 0.74 38.92 24.91
191 INT107577 Negative_regulation of Grin2b 32 0.59 12.35 24.88
192 INT12484 Binding of Drd2 45 0.48 15.17 24.72
193 INT2140 Regulation of REN 104 0.62 28.24 24.49
194 INT48240 Binding of Ngf 46 0.46 23.51 24.42
195 INT6441 Positive_regulation of CRH 98 0.69 57.22 24.12
196 INT47818 Positive_regulation of Homer1 48 0.70 11.11 24.05
197 INT682 Negative_regulation of AVP 97 0.59 50.67 23.91
198 INT44954 Gene_expression of APP 191 0.78 105.86 23.9
199 INT15390 Positive_regulation of Edn1 64 0.70 47.36 23.8
200 INT2290 Protein_catabolism of POMC 41 0.99 4.86 23.36
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