GO:0005105

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Name type 1 fibroblast growth factor receptor binding
Categary Function
Go Slim No
Go Link GO:0005105
Unique Molecular Interactions 39
Total Molecular Interactions 63
Total Single Events 212
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for type 1 fibroblast growth factor receptor binding. They are ordered first by their pain relevance and then by number of times they were reported for type 1 fibroblast growth factor receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
2 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93
3 INT250861 Fgf8 Positive_regulation of Gene_expression of Ptger2 1 0.04 1.51 0.84
4 INT250852 Fgf8 Negative_regulation of Gene_expression of Ecm1 1 0.04 1.1 0.54
5 INT250870 Fgf8 Positive_regulation of Ecm1 1 0.04 0.79 0.38
6 INT250856 Fgf8 Positive_regulation of Localization of Mmp3 1 0.11 0.51 0.3
7 INT335027 Binding of Vdr and Fgf23 1 0.24 0.34 0.29
8 INT250864 Fgf8 Positive_regulation of Positive_regulation of Ptger2 1 0.03 0.55 0.28
9 INT250854 Fgf8 Positive_regulation of Positive_regulation of Mmp3 1 0.11 0.55 0.28
10 INT250873 Fgf8 Positive_regulation of GAG 1 0.55 0.48 0.23
11 INT335021 Fgf23 Negative_regulation of Gene_expression of Cyp27b1 1 0.53 1.49 0.21
12 INT335020 Fgf23 Positive_regulation of Gene_expression of Cyp24a1 1 0.62 0.82 0.18
13 INT335018 Vdr Positive_regulation of Gene_expression of Fgf23 1 0.44 0.36 0.17
14 INT250863 Fgf8 Positive_regulation of Ptger2 1 0.03 0.19 0.14
15 INT335026 Positive_regulation of Fgf23 Positive_regulation of Gene_expression of Cyp24a1 1 0.45 0.2 0.13
16 INT335024 Positive_regulation of Fgf23 Negative_regulation of Gene_expression of Cyp27b1 1 0.39 0.19 0.13
17 INT250866 Binding of Fgfr4 and Fgf8 1 0.12 0.35 0.11
18 INT250860 Fgf8 Regulation of Localization of Ptger2 1 0.02 0.13 0.1
19 INT250862 Fgf8 Regulation of Localization of Mmp3 1 0.13 0.13 0.1
20 INT250859 Fgf8 Negative_regulation of Gene_expression of Mmp3 1 0.09 0.12 0.09
21 INT250872 Fgf8 Positive_regulation of Mmp3 1 0.11 0.12 0.09
22 INT250865 Binding of Fgf8 and Fgfr3 1 0.18 0.3 0.05
23 INT250855 Binding of Fgfr2 and Fgf8 1 0.12 0.3 0.05
24 INT335017 Fgf23 Positive_regulation of Fgfr1 1 0.23 0.59 0.04
25 INT335016 Fgf23 Negative_regulation of Gene_expression of Slc34a3 1 0.03 0.63 0.03
26 INT316598 Pth Regulation of Fgf23 1 0.10 0.28 0.03
27 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
28 INT203411 Mllt11 Negative_regulation of Nptn 1 0.08 0.58 0
29 INT203414 Vsnl1 Negative_regulation of Nptn 1 0.16 0.58 0
30 INT203398 Enc1 Negative_regulation of Nptn 1 0.07 0.59 0
31 INT266837 Dmp1 Negative_regulation of Gene_expression of Fgf23 1 0.48 2.41 0
32 INT203392 Olfm1 Negative_regulation of Nptn 1 0.08 0.58 0
33 INT203407 Cap2 Negative_regulation of Nptn 1 0.06 0.59 0
34 INT266839 Fgf23 Negative_regulation of Slc34a1 1 0.21 0.88 0
35 INT301366 Fgf18 Positive_regulation of Fgfr3 1 0.04 0.34 0
36 INT335019 Fgf23 Positive_regulation of Phosphorylation of Mapk1 1 0.08 0.45 0
37 INT266833 Phex Regulation of Gene_expression of Fgf23 1 0.23 0.46 0
38 INT266838 Fgf23 Regulation of Slc34a1 1 0.13 0.3 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for type 1 fibroblast growth factor receptor binding. They are ordered first by their pain relevance and then by number of times they were reported in type 1 fibroblast growth factor receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT250832 Gene_expression of Fgf8 1 0.77 13.36 6.2
2 INT250841 Positive_regulation of Gene_expression of Fgf8 1 0.69 3.8 1.72
3 INT250850 Negative_regulation of Gene_expression of Fgf8 1 0.42 2.79 1.33
4 INT250840 Negative_regulation of Fgf8 1 0.43 1.92 1.11
5 INT277461 Positive_regulation of Gene_expression of Fgf8 1 0.24 0.47 1.05
6 INT118373 Gene_expression of Fgf23 16 0.77 29.62 1.04
7 INT118371 Positive_regulation of Fgf23 15 0.69 25.34 0.85
8 INT130797 Gene_expression of Fgf23 6 0.66 4.73 0.77
9 INT250845 Protein_catabolism of Fgf8 1 0.98 1.64 0.48
10 INT268007 Gene_expression of Fgf8 8 0.72 1.38 0.47
11 INT277465 Regulation of Gene_expression of Fgf8 2 0.25 0.43 0.43
12 INT250826 Transcription of Fgf8 1 0.71 0.71 0.34
13 INT135880 Positive_regulation of Gene_expression of Fgf23 4 0.46 7.52 0.29
14 INT130799 Localization of Fgf23 2 0.63 1.94 0.28
15 INT157409 Negative_regulation of Fgf23 3 0.50 3.21 0.27
16 INT250836 Binding of Fgf8 3 0.35 0.66 0.24
17 INT250833 Localization of Fgf8 1 0.74 0.46 0.21
18 INT250842 Negative_regulation of Binding of Fgf8 1 0.43 0.33 0.21
19 INT130798 Positive_regulation of Gene_expression of Fgf23 2 0.59 1.12 0.2
20 INT118372 Regulation of Fgf23 4 0.55 3.31 0.15
21 INT250835 Positive_regulation of Fgf8 1 0.50 0.42 0.14
22 INT295974 Regulation of Fgf23 1 0.07 2.3 0.11
23 INT266826 Binding of Fgf23 1 0.32 1.26 0.07
24 INT268298 Gene_expression of Fgf18 1 0.22 0.44 0.05
25 INT268307 Positive_regulation of Fgf18 1 0.25 0.44 0.05
26 INT266828 Negative_regulation of Fgf23 3 0.42 5.63 0.04
27 INT316595 Transcription of Fgf23 1 0.61 0.44 0.04
28 INT316589 Negative_regulation of Transcription of Fgf23 1 0.50 0.44 0.04
29 INT335007 Protein_catabolism of Fgf23 1 0.59 1.28 0.03
30 INT316588 Positive_regulation of Fgf23 1 0.43 0.29 0.03
31 INT203350 Gene_expression of Nptn 1 0.16 0.4 0.03
32 INT150308 Protein_catabolism of Fgf23 1 0.75 0.05 0
33 INT334982 Phosphorylation of Fgf23 1 0.73 1.21 0
34 INT335003 Negative_regulation of Localization of Fgf23 1 0.39 2.37 0
35 INT334997 Localization of Fgf23 1 0.72 3.56 0
36 INT266824 Regulation of Positive_regulation of Fgf23 1 0.27 1.22 0
37 INT250830 Regulation of Protein_catabolism of Fgf8 1 0.45 0.08 0
38 INT311651 Positive_regulation of Fgf8 1 0.46 0.26 0
39 INT334991 Positive_regulation of Positive_regulation of Fgf23 1 0.39 1.5 0
40 INT150307 Positive_regulation of Protein_catabolism of Fgf23 1 0.52 0.11 0
41 INT266825 Positive_regulation of Regulation of Fgf23 1 0.46 0.25 0
42 INT334993 Negative_regulation of Gene_expression of Fgf23 1 0.38 4.1 0
43 INT250846 Positive_regulation of Protein_catabolism of Fgf8 1 0.50 0.07 0
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