GO:0005111

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Name type 2 fibroblast growth factor receptor binding
Categary Function
Go Slim No
Go Link GO:0005111
Unique Molecular Interactions 31
Total Molecular Interactions 49
Total Single Events 317
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for type 2 fibroblast growth factor receptor binding. They are ordered first by their pain relevance and then by number of times they were reported for type 2 fibroblast growth factor receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
2 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93
3 INT250861 Fgf8 Positive_regulation of Gene_expression of Ptger2 1 0.04 1.51 0.84
4 INT250852 Fgf8 Negative_regulation of Gene_expression of Ecm1 1 0.04 1.1 0.54
5 INT250870 Fgf8 Positive_regulation of Ecm1 1 0.04 0.79 0.38
6 INT250856 Fgf8 Positive_regulation of Localization of Mmp3 1 0.11 0.51 0.3
7 INT250864 Fgf8 Positive_regulation of Positive_regulation of Ptger2 1 0.03 0.55 0.28
8 INT250854 Fgf8 Positive_regulation of Positive_regulation of Mmp3 1 0.11 0.55 0.28
9 INT250873 Fgf8 Positive_regulation of GAG 1 0.55 0.48 0.23
10 INT250863 Fgf8 Positive_regulation of Ptger2 1 0.03 0.19 0.14
11 INT250866 Binding of Fgfr4 and Fgf8 1 0.12 0.35 0.11
12 INT199595 FGF7 Positive_regulation of Transcription of TNF 1 0.40 0.58 0.11
13 INT250860 Fgf8 Regulation of Localization of Ptger2 1 0.02 0.13 0.1
14 INT250862 Fgf8 Regulation of Localization of Mmp3 1 0.13 0.13 0.1
15 INT250859 Fgf8 Negative_regulation of Gene_expression of Mmp3 1 0.09 0.12 0.09
16 INT250872 Fgf8 Positive_regulation of Mmp3 1 0.11 0.12 0.09
17 INT199594 FGF7 Positive_regulation of NFE2L2 1 0.01 0.52 0.09
18 INT199604 Binding of FGF7 and Fgf1 1 0.03 0.21 0.08
19 INT199603 Positive_regulation of Binding of FGF7 and Fgf1 1 0.04 0.21 0.08
20 INT303561 Binding of Fgf7 and Fgfr2 1 0.42 0.88 0.07
21 INT303562 Binding of Fgf10 and Fgfr2 1 0.40 0.88 0.07
22 INT250865 Binding of Fgf8 and Fgfr3 1 0.18 0.3 0.05
23 INT250855 Binding of Fgfr2 and Fgf8 1 0.12 0.3 0.05
24 INT303563 Binding of Fgf10 and Dysf 1 0.00 0.44 0.03
25 INT303559 Binding of Fgf7 and Dysf 1 0.01 0.44 0.03
26 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
27 INT306114 GOPC Regulation of Gene_expression of FGF7 1 0.05 0.45 0
28 INT319042 Negative_regulation of Binding of Fgf7 and Fig4 1 0.07 0.2 0
29 INT202675 Fgf10 Positive_regulation of Fgfr2 1 0.45 0.07 0
30 INT301366 Fgf18 Positive_regulation of Fgfr3 1 0.04 0.34 0
31 INT319043 Binding of Fgf7 and Fig4 1 0.06 0.26 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for type 2 fibroblast growth factor receptor binding. They are ordered first by their pain relevance and then by number of times they were reported in type 2 fibroblast growth factor receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT250832 Gene_expression of Fgf8 1 0.77 13.36 6.2
2 INT83374 Gene_expression of FGF7 83 0.78 44.18 2.6
3 INT250841 Positive_regulation of Gene_expression of Fgf8 1 0.69 3.8 1.72
4 INT181032 Gene_expression of Fgf7 8 0.61 5.96 1.41
5 INT250850 Negative_regulation of Gene_expression of Fgf8 1 0.42 2.79 1.33
6 INT199601 Positive_regulation of FGF7 9 0.50 6.13 1.22
7 INT250840 Negative_regulation of Fgf8 1 0.43 1.92 1.11
8 INT277461 Positive_regulation of Gene_expression of Fgf8 1 0.24 0.47 1.05
9 INT199598 Binding of FGF7 4 0.48 2.83 0.9
10 INT99708 Gene_expression of Fgf7 7 0.76 7.42 0.7
11 INT124042 Localization of FGF7 10 0.80 4.13 0.57
12 INT296583 Gene_expression of Fgf10 3 0.59 2.64 0.57
13 INT296594 Regulation of Fgf10 1 0.15 1.53 0.56
14 INT199602 Positive_regulation of Gene_expression of FGF7 12 0.70 7.47 0.55
15 INT250845 Protein_catabolism of Fgf8 1 0.98 1.64 0.48
16 INT268007 Gene_expression of Fgf8 8 0.72 1.38 0.47
17 INT277465 Regulation of Gene_expression of Fgf8 2 0.25 0.43 0.43
18 INT262902 Regulation of Binding of FGF7 1 0.02 0.88 0.4
19 INT228271 Localization of Fgf7 2 0.28 1.59 0.39
20 INT250826 Transcription of Fgf8 1 0.71 0.71 0.34
21 INT228280 Regulation of Gene_expression of Fgf7 1 0.18 0.95 0.34
22 INT257954 Regulation of FGF7 2 0.45 0.52 0.32
23 INT250836 Binding of Fgf8 3 0.35 0.66 0.24
24 INT250833 Localization of Fgf8 1 0.74 0.46 0.21
25 INT250842 Negative_regulation of Binding of Fgf8 1 0.43 0.33 0.21
26 INT199599 Negative_regulation of Gene_expression of FGF7 3 0.48 0.78 0.19
27 INT199600 Negative_regulation of Localization of FGF7 1 0.35 1.09 0.16
28 INT99709 Regulation of Gene_expression of Fgf7 3 0.44 0.19 0.14
29 INT250835 Positive_regulation of Fgf8 1 0.50 0.42 0.14
30 INT285494 Positive_regulation of Gene_expression of Fgf7 2 0.40 1.48 0.13
31 INT119194 Negative_regulation of FGF7 2 0.43 1.42 0.13
32 INT285509 Negative_regulation of Gene_expression of Fgf7 1 0.14 1.14 0.1
33 INT99713 Positive_regulation of Gene_expression of Fgf7 3 0.45 0.92 0.07
34 INT200103 Regulation of Gene_expression of FGF7 3 0.62 3.41 0.06
35 INT268298 Gene_expression of Fgf18 1 0.22 0.44 0.05
36 INT268307 Positive_regulation of Fgf18 1 0.25 0.44 0.05
37 INT178418 Binding of Fgf7 1 0.16 1.26 0.05
38 INT260760 Positive_regulation of Fgf10 2 0.53 0.43 0.03
39 INT178396 Positive_regulation of Fgf7 2 0.55 0.98 0.03
40 INT303535 Positive_regulation of Gene_expression of Fgf10 1 0.53 0.34 0.03
41 INT99714 Transcription of Fgf7 2 0.67 0.22 0
42 INT319037 Positive_regulation of Regulation of Fgf7 1 0.49 0.08 0
43 INT319041 Regulation of Fgf7 1 0.44 0.08 0
44 INT306120 Regulation of Transcription of FGF7 1 0.62 1.47 0
45 INT319039 Negative_regulation of Fgf7 1 0.42 0.18 0
46 INT306124 Transcription of FGF7 1 0.72 3.68 0
47 INT250830 Regulation of Protein_catabolism of Fgf8 1 0.45 0.08 0
48 INT311651 Positive_regulation of Fgf8 1 0.46 0.26 0
49 INT306126 Negative_regulation of Transcription of FGF7 1 0.43 0.56 0
50 INT319038 Negative_regulation of Gene_expression of Fgf7 1 0.42 0.18 0
51 INT250846 Positive_regulation of Protein_catabolism of Fgf8 1 0.50 0.07 0
52 INT319040 Protein_catabolism of Fgf7 1 0.64 0.17 0
53 INT306121 Positive_regulation of Localization of FGF7 1 0.50 0.12 0
54 INT239107 Binding of Fgf7 1 0.16 0.35 0
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