GO:0005121

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Name Toll binding
Categary Function
Go Slim No
Go Link GO:0005121
Unique Molecular Interactions 36
Total Molecular Interactions 57
Total Single Events 167
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for Toll binding. They are ordered first by their pain relevance and then by number of times they were reported for Toll binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
2 INT316690 Binding of Myd88 and Il1 2 0.06 1.75 0.66
3 INT348790 Binding of MYD88 and Tlr4 1 0.35 1.84 0.4
4 INT203085 Positive_regulation of Binding of Il1a and Myd88 1 0.07 0.65 0.32
5 INT203087 Binding of Il1a and Myd88 1 0.05 0.65 0.31
6 INT324825 Binding of Chuk and Myd88 1 0.03 0.86 0.28
7 INT288205 Binding of Cd14 and Myd88 1 0.10 0.57 0.28
8 INT324806 Positive_regulation of Binding of Chuk and Myd88 1 0.04 0.86 0.28
9 INT256063 Myd88 Positive_regulation of Gene_expression of Mcpt1 1 0.13 0.56 0.27
10 INT292557 Binding of F2RL1 and MYD88 1 0.08 0.52 0.22
11 INT254219 Binding of Myd88 and Tlr2 2 0.16 0.6 0.2
12 INT348789 Positive_regulation of Binding of MYD88 and Tlr4 1 0.46 0.93 0.2
13 INT179504 Tlr4 Regulation of Myd88 1 0.07 0.29 0.17
14 INT254214 Binding of Myd88 and Tirap 1 0.15 0.55 0.17
15 INT278373 Myd88 Regulation of Phosphorylation of Syk 1 0.15 0.35 0.15
16 INT278394 Myd88 Regulation of Phosphorylation of Hps5 1 0.11 0.35 0.15
17 INT193693 Binding of Myd88 and Pain1 1 0.14 0.82 0.13
18 INT346501 MYD88 Positive_regulation of Nfkb1 1 0.01 0.5 0.13
19 INT254201 Myd88 Positive_regulation of Ik 1 0.00 0.14 0.12
20 INT329798 Binding of MYD88 and TICAM1 2 0.01 0.24 0.1
21 INT343855 Binding of MYD88 and PIK3CG 1 0.03 0.26 0.1
22 INT343858 Binding of AKT1 and MYD88 1 0.02 0.26 0.1
23 INT334266 Binding of Irak1 and Myd88 2 0.35 0.16 0.09
24 INT350073 Binding of co and Myd88 1 0.00 0.17 0.08
25 INT254223 Tlr3 Positive_regulation of Myd88 1 0.16 0.23 0.08
26 INT350481 Tlr4 Positive_regulation of Gene_expression of Myd88 1 0.26 0.06 0.06
27 INT334260 Negative_regulation of Binding of Myd88 and Il1 1 0.01 0.4 0.06
28 INT334258 Binding of Myd88 and Irak4 2 0.26 0.24 0.05
29 INT350802 Binding of MYD88 and TLR3 1 0.01 0 0.04
30 INT334262 Myd88 Positive_regulation of Tlr7 1 0.05 0.3 0.04
31 INT238008 Myd88 Regulation of Hand1 1 0.03 0.82 0.04
32 INT290313 Binding of MYD88 and TLR7 1 0.03 0.1 0.03
33 INT299006 Binding of Il18 and Myd88 1 0.21 0.19 0.03
34 INT350077 Negative_regulation of Binding of Myd88 and Tlr4 1 0.12 0.16 0
35 INT348039 Binding of Myd88 and Irak2 1 0.22 0 0
36 INT324696 Binding of Myd88 and Mapk10 1 0.05 0.68 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for Toll binding. They are ordered first by their pain relevance and then by number of times they were reported in Toll binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT197491 Gene_expression of Myd88 32 0.74 14.59 5.29
2 INT142752 Positive_regulation of Myd88 26 0.66 12.07 4.4
3 INT142754 Binding of Myd88 20 0.36 9.61 3.8
4 INT233975 Positive_regulation of Gene_expression of Myd88 7 0.66 4.17 1.65
5 INT246928 Negative_regulation of Myd88 12 0.38 6.16 1.3
6 INT233970 Regulation of Myd88 7 0.45 5.2 1.28
7 INT237858 Positive_regulation of MYD88 5 0.49 2.93 0.9
8 INT250171 Localization of Myd88 4 0.72 1.95 0.88
9 INT166126 Gene_expression of MYD88 5 0.54 2.67 0.84
10 INT264973 Binding of MYD88 4 0.35 1.2 0.74
11 INT334226 Positive_regulation of Localization of Myd88 1 0.36 0.54 0.67
12 INT233973 Negative_regulation of Gene_expression of Myd88 4 0.38 1.32 0.61
13 INT264963 Positive_regulation of Binding of MYD88 1 0.17 0.18 0.52
14 INT246422 Transcription of MYD88 2 0.52 0.77 0.38
15 INT256056 Positive_regulation of Binding of Myd88 2 0.48 0.36 0.36
16 INT203076 Positive_regulation of Positive_regulation of Myd88 1 0.19 0.65 0.32
17 INT203072 Positive_regulation of Myd88 1 0.19 0.65 0.32
18 INT197492 Regulation of Gene_expression of Myd88 2 0.39 1.95 0.27
19 INT242901 Regulation of Gene_expression of MYD88 2 0.18 0.19 0.19
20 INT242897 Positive_regulation of Gene_expression of MYD88 2 0.20 0.27 0.19
21 INT233971 Transcription of Myd88 2 0.60 1.01 0.17
22 INT334237 Negative_regulation of Binding of Myd88 1 0.30 1.16 0.12
23 INT306310 Positive_regulation of Positive_regulation of Myd88 1 0.38 0.41 0.12
24 INT242898 Regulation of MYD88 2 0.33 0.88 0.11
25 INT329055 Gene_expression of Myd88 1 0.72 1.18 0.11
26 INT334227 Positive_regulation of Regulation of Myd88 1 0.36 0.63 0.08
27 INT329054 Negative_regulation of Gene_expression of Myd88 1 0.54 0.13 0.06
28 INT329067 Positive_regulation of Gene_expression of Myd88 1 0.64 0.12 0.05
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