GO:0005125

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Name cytokine activity
Categary Function
Go Slim No
Go Link GO:0005125
Unique Molecular Interactions 9400
Total Molecular Interactions 13499
Total Single Events 109583
Pain Genes Associated 226

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cytokine activity. They are ordered first by their pain relevance and then by number of times they were reported for cytokine activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
2 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62
3 INT79759 Ngf Regulation of Il6 1 0.60 4.62 5.62
4 INT140935 Binding of Cd40lg and Cd40 1 0.30 6.34 5.61
5 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
6 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
7 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
8 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
9 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
10 INT64756 oh Negative_regulation of Gpi1 1 0.03 0 4.09
11 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01
12 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
13 INT69032 IL18 Positive_regulation of IFNA1 12 0.23 7.87 3.83
14 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66
15 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
16 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27
17 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
18 INT91271 Mtr Regulation of Gene_expression of Il6 1 0.20 0 3.17
19 INT17456 Binding of CSF2 and POMC 3 0.32 4.06 3.15
20 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
21 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11
22 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95
23 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
24 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
25 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
26 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
27 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
28 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
29 INT69030 IL18 Positive_regulation of IL12A 3 0.31 5.57 2.72
30 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
31 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
32 INT87267 Binding of BMP8B and KRIT1 1 0.06 0.16 2.69
33 INT62450 Il2 Positive_regulation of Localization of Crh 1 0.43 0.59 2.64
34 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
35 INT189490 Binding of Ccr3 and Ccl5 1 0.33 8.54 2.6
36 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
37 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
38 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
39 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
40 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
41 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
42 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
43 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
44 INT107578 Kitl Negative_regulation of Grin2b 1 0.12 2.05 2.36
45 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
46 INT350148 Binding of IL12A and ERAL1 1 0.21 8.23 2.26
47 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
48 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
49 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
50 INT155984 Il1a Negative_regulation of Gene_expression of Cyp3a11 1 0.24 0.92 2.2
51 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
52 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
53 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
54 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
55 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
56 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
57 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
58 INT184262 Binding of AGER and HMGB1 1 0.34 4.49 2.17
59 INT319581 Binding of PIAS1 and TNFSF14 1 0.02 1.58 2.13
60 INT140019 Avp Positive_regulation of Localization of Kitl 1 0.00 1 2.13
61 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
62 INT83425 Binding of CD40LG and IGHG3 11 0.21 4.56 2.09
63 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
64 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
65 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
66 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
67 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
68 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
69 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
70 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
71 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
72 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
73 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
74 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
75 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
76 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
77 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91
78 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
79 INT91607 Binding of EDN1 and POMC 1 0.12 0 1.9
80 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88
81 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
82 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
83 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
84 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
85 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
86 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
87 INT203149 Binding of Mif and Osm 1 0.02 2.93 1.78
88 INT165183 Ifnb1 Positive_regulation of P2rx4 1 0.04 1.73 1.73
89 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
90 INT158302 Il23a Regulation of Gene_expression of Il17a 1 0.06 1.45 1.7
91 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
92 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
93 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
94 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
95 INT150232 Samhd1 Positive_regulation of Gene_expression of TNFSF13B 1 0.01 1.74 1.67
96 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
97 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
98 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
99 INT140023 Avp Positive_regulation of Gene_expression of Kitl 1 0.00 0.76 1.62
100 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
101 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
102 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
103 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
104 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
105 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
106 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
107 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
108 INT306745 Binding of Il12a and IL23A 1 0.10 3.25 1.56
109 INT76651 Cpe Positive_regulation of Gene_expression of Il6 1 0.08 0 1.56
110 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
111 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55
112 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
113 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
114 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54
115 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
116 INT69031 IL12A Positive_regulation of IFNA1 9 0.13 4.23 1.52
117 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
118 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
119 INT135276 Gt(pU21)50Imeg Negative_regulation of Gene_expression of Il6 1 0.02 0.52 1.52
120 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
121 INT76656 POMC Positive_regulation of Gene_expression of Il6 1 0.03 0 1.51
122 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
123 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
124 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
125 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49
126 INT92057 Ifng Positive_regulation of Gene_expression of Ik 1 0.03 0.45 1.49
127 INT190772 Il4 Negative_regulation of Gene_expression of Ptger2 1 0.03 1.28 1.49
128 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47
129 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
130 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
131 INT21536 Binding of Il2 and Il1 1 0.28 0 1.47
132 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
133 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
134 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
135 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45
136 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45
137 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44
138 INT158282 Binding of Penk and Csf2 1 0.33 0.87 1.44
139 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
140 INT238005 Binding of Cxcr3 and Cxcl10 2 0.38 3.73 1.42
141 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
142 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
143 INT83626 Ifng Positive_regulation of Gene_expression of Cd59 1 0.33 2.19 1.41
144 INT190775 Gene_expression of Il4 Negative_regulation of Positive_regulation of FOSL1 1 0.39 2.42 1.4
145 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4
146 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4
147 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39
148 INT238009 Binding of Cxcr3 and Cxcl9 3 0.40 4.01 1.37
149 INT87266 Negative_regulation of Binding of BMP8B and KRIT1 1 0.05 0.07 1.37
150 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
151 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
152 INT177457 Il1 Positive_regulation of Gene_expression of Il6 3 0.16 4.47 1.35
153 INT160590 CSF2 Positive_regulation of Gene_expression of OPRM1 1 0.16 0.54 1.35
154 INT176368 IL18 Positive_regulation of Gene_expression of IFNA1 1 0.16 2.53 1.35
155 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
156 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
157 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
158 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
159 INT160587 IFNG Positive_regulation of Gene_expression of OPRM1 1 0.18 0.54 1.35
160 INT160585 IL18 Positive_regulation of Gene_expression of OPRM1 1 0.09 0.54 1.35
161 INT160589 IL4 Positive_regulation of Gene_expression of OPRM1 1 0.13 0.54 1.35
162 INT86172 Pdyn Positive_regulation of Gene_expression of Il2 1 0.20 0 1.33
163 INT264327 IL-17 Positive_regulation of Gene_expression of Tnfsf11 1 0.07 3.19 1.33
164 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
165 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
166 INT95093 ITIH4 Positive_regulation of IL1B 1 0.43 1.04 1.32
167 INT95094 Negative_regulation of ITIH4 Positive_regulation of IL1B 1 0.36 1.04 1.32
168 INT182096 Positive_regulation of Binding of Il6 and Il1 2 0.09 4.26 1.31
169 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
170 INT27425 Mtr Positive_regulation of Gene_expression of Il1f5 1 0.06 0 1.3
171 INT62448 Il2 Positive_regulation of Crh 1 0.59 0.36 1.3
172 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
173 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
174 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
175 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
176 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
177 INT89943 Binding of Oprm1 and Il2 1 0.03 0.53 1.28
178 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
179 INT34052 POMC Regulation of Gene_expression of IFNG 1 0.11 0 1.27
180 INT51388 Binding of CSF2 and RPLP0 1 0.11 1.8 1.27
181 INT181436 Binding of Ccl2 and Eae1 1 0.05 5.14 1.27
182 INT8409 IL1A Positive_regulation of Positive_regulation of Vip 1 0.01 0.63 1.27
183 INT87026 ZAK Positive_regulation of Gene_expression of IL12A 3 0.12 2.55 1.26
184 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
185 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26
186 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
187 INT236835 Binding of CISH and CSF2 1 0.06 1.43 1.25
188 INT254210 Binding of Cxcr2 and Ccl2 1 0.08 2.39 1.25
189 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
190 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24
191 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
192 INT64758 Negative_regulation of oh Negative_regulation of Gpi1 1 0.03 0 1.24
193 INT108389 IL1B Positive_regulation of ADAMTS4 1 0.51 1.19 1.24
194 INT172141 IL10 Negative_regulation of Gene_expression of HLA-DRA 2 0.14 0.89 1.23
195 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
196 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
197 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
198 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
199 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
200 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22

Single Events

The table below shows the top 100 pain related interactions that have been reported for cytokine activity. They are ordered first by their pain relevance and then by number of times they were reported in cytokine activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
3 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
4 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
5 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
6 INT6852 Localization of TNF 883 0.81 705.95 270.84
7 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57
8 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
9 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
10 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
11 INT6481 Binding of TNF 624 0.48 510.2 214.82
12 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
13 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
14 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
15 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
16 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
17 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69
18 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69
19 INT9660 Regulation of TNF 363 0.62 312.94 139.99
20 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52
21 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28
22 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
23 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12
24 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06
25 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
26 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84
27 INT12082 Localization of IL6 365 0.81 241.78 105.78
28 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
29 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
30 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89
31 INT10166 Localization of Tnf 237 0.81 153.95 88.64
32 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
33 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96
34 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35
35 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57
36 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
37 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42
38 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
39 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92
40 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
41 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14
42 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38
43 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
44 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
45 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
46 INT6849 Localization of IL1B 229 0.81 112.56 69.63
47 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6
48 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
49 INT19511 Localization of Il6 212 0.81 118.17 67.67
50 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41
51 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
52 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73
53 INT11807 Gene_expression of Il2 266 0.78 112 64.97
54 INT11937 Localization of Il6 228 0.81 139.83 64.39
55 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6
56 INT10706 Regulation of Il6 150 0.62 93.23 62.34
57 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
58 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72
59 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
60 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69
61 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
62 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
63 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
64 INT12345 Gene_expression of Il2 142 0.78 59.17 51.21
65 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
66 INT9210 Regulation of IL6 166 0.62 125.61 49.95
67 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
68 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
69 INT5781 Gene_expression of Edn1 190 0.78 99.1 46
70 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33
71 INT1726 Positive_regulation of Kitl 65 0.70 38.81 44.85
72 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
73 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23
74 INT83953 Gene_expression of Cxcl2 140 0.75 113.07 43.65
75 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5
76 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
77 INT100939 Gene_expression of Il13 176 0.73 125.1 43.38
78 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32
79 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07
80 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
81 INT13354 Transcription of TNF 108 0.72 85.81 42.32
82 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97
83 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
84 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24
85 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48
86 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
87 INT11439 Positive_regulation of Csf2 105 0.69 62.63 37.77
88 INT104551 Gene_expression of Il18 156 0.76 115.51 36.95
89 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
90 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
91 INT48896 Positive_regulation of Gene_expression of Il10 73 0.70 43.14 35.5
92 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
93 INT6484 Binding of IL1B 122 0.47 75.84 35.07
94 INT20380 Gene_expression of Il5 172 0.78 104.75 34.78
95 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67
96 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19
97 INT104392 Gene_expression of Cxcl10 113 0.75 106.86 34.12
98 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66
99 INT10763 Localization of IL2 157 0.80 81.11 33.21
100 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07
101 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58
102 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26
103 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22
104 INT9655 Regulation of Il6 98 0.62 70.92 31.95
105 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7
106 INT35406 Localization of Tnf 94 0.81 64.63 31.65
107 INT9347 Localization of Il1b 58 0.81 26.13 31.53
108 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
109 INT94388 Gene_expression of GDF15 124 0.77 79.48 31.42
110 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4
111 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
112 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
113 INT129207 Gene_expression of Cxcl1 114 0.75 68.54 30.82
114 INT54302 Positive_regulation of Gene_expression of Il4 126 0.68 86.18 30.75
115 INT9993 Positive_regulation of Gene_expression of IL2 131 0.69 46.27 30.04
116 INT90792 Localization of Il10 144 0.80 87.88 30.03
117 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96
118 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
119 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44
120 INT86437 Binding of IL6 154 0.48 121.22 29.3
121 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43
122 INT57692 Positive_regulation of Gene_expression of Il1b 50 0.67 43.54 28.29
123 INT116737 Localization of Mif 63 0.81 52.97 28.11
124 INT14690 Localization of CSF2 124 0.80 85.17 27.26
125 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81
126 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
127 INT5966 Localization of Il1a 50 0.78 22.91 26.54
128 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
129 INT135411 Gene_expression of Il23a 76 0.72 72.87 26.15
130 INT20044 Negative_regulation of Gpi1 50 0.59 29.96 26
131 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95
132 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66
133 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
134 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11
135 INT56224 Negative_regulation of Gene_expression of Ifng 40 0.58 23.34 25.08
136 INT130186 Gene_expression of Ccl5 101 0.74 79.96 25.01
137 INT43486 Positive_regulation of Ifng 52 0.69 32.71 24.77
138 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
139 INT8518 Localization of Ifng 53 0.81 36.68 24.13
140 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07
141 INT15390 Positive_regulation of Edn1 64 0.70 47.36 23.8
142 INT51029 Negative_regulation of Il1b 34 0.57 29.34 23.62
143 INT11746 Positive_regulation of Il1a 65 0.63 42.94 23.54
144 INT50039 Positive_regulation of Il4 48 0.55 34.8 23.34
145 INT110427 Gene_expression of Spp1 199 0.78 176.11 23.31
146 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26
147 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05
148 INT74423 Localization of IL10 91 0.80 61.6 22.95
149 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76
150 INT48081 Localization of Il1b 46 0.80 21.59 22.4
151 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
152 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
153 INT150022 Positive_regulation of Il17a 69 0.64 70.04 21.87
154 INT11804 Positive_regulation of Gene_expression of Il2 70 0.70 33 21.63
155 INT116856 Gene_expression of TNFSF10 110 0.75 115.76 21.48
156 INT48692 Binding of VEGFA 345 0.48 210.3 21.31
157 INT160564 Gene_expression of Il22 64 0.55 59.29 20.9
158 INT60690 Positive_regulation of Gene_expression of Il12a 69 0.63 41.41 20.85
159 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
160 INT15796 Regulation of IL2 66 0.61 25.43 20.62
161 INT20379 Localization of Il4 85 0.73 51.22 20.55
162 INT51474 Binding of Il6 55 0.48 44.99 20.52
163 INT86751 Negative_regulation of Il10 62 0.59 40.1 20.51
164 INT48144 Gene_expression of Fgf2 117 0.78 43 20.48
165 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39
166 INT57257 Gene_expression of IL7 69 0.62 50.24 20.36
167 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34
168 INT49985 Transcription of Il6 62 0.72 40.13 20.29
169 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28
170 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14
171 INT88949 Positive_regulation of Il12a 79 0.60 47.68 19.98
172 INT104395 Gene_expression of Cxcl9 83 0.76 73.1 19.79
173 INT69304 Negative_regulation of Il10 47 0.59 36.88 19.79
174 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
175 INT89484 Gene_expression of TNFRSF11B 119 0.76 53.57 19.67
176 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59
177 INT7994 Gene_expression of Lta 113 0.67 69.81 19.59
178 INT138696 Positive_regulation of Ccl2 57 0.67 59.57 19.58
179 INT25222 Positive_regulation of Gene_expression of Ifng 32 0.50 24.18 19.58
180 INT74286 Regulation of Il10 42 0.44 28.06 19.44
181 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
182 INT16445 Gene_expression of IL1A 60 0.78 44.46 19.19
183 INT5048 Binding of Edn1 55 0.47 18.86 19.16
184 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
185 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
186 INT11803 Positive_regulation of Il2 62 0.70 31.44 18.93
187 INT19509 Localization of Ifng 55 0.78 28.25 18.67
188 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65
189 INT101988 Positive_regulation of GDF15 71 0.69 51.03 18.56
190 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46
191 INT87861 Gene_expression of Il18 33 0.78 30.44 18.42
192 INT35086 Positive_regulation of Gene_expression of Ifng 40 0.69 22.55 18.35
193 INT11938 Positive_regulation of Localization of Il6 61 0.70 35.72 18.25
194 INT5967 Negative_regulation of Il1a 51 0.57 27.09 18.24
195 INT61626 Transcription of IL6 73 0.72 42.04 17.86
196 INT113602 Positive_regulation of Gene_expression of Ccl2 48 0.70 48.71 17.85
197 INT9656 Regulation of Gene_expression of Il6 57 0.62 33.3 17.71
198 INT168263 Gene_expression of IL23A 57 0.58 47.1 17.67
199 INT72564 Localization of Il10 41 0.78 28.62 17.6
200 INT104550 Positive_regulation of Il18 67 0.70 55.14 17.48
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