GO:0005131

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Name growth hormone receptor binding
Categary Function
Go Slim No
Go Link GO:0005131
Unique Molecular Interactions 1044
Total Molecular Interactions 1749
Total Single Events 20545
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for growth hormone receptor binding. They are ordered first by their pain relevance and then by number of times they were reported for growth hormone receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 0.64 2.12 14.2
2 INT26468 Ghrh Positive_regulation of Localization of Gh 21 0.37 3.26 9.21
3 INT10844 Ghrh Regulation of Gh 13 0.13 4.77 4.71
4 INT16221 Ghrh Positive_regulation of Gh 8 0.21 1.89 4.08
5 INT11248 Gh Positive_regulation of Ghrh 2 0.26 0.09 4.04
6 INT13729 GHRH Positive_regulation of Localization of GH1 13 0.62 0.59 3.2
7 INT26892 OGG1 Negative_regulation of Gene_expression of Gh1 1 0.12 0 2.53
8 INT20411 Ghrh Positive_regulation of Gh1 6 0.56 0.62 2.47
9 INT7367 Ghrh Regulation of Localization of Gh1 5 0.49 1.55 2.25
10 INT9180 Ghrh Regulation of Localization of Gh 3 0.24 0.25 2.18
11 INT3576 Sst Negative_regulation of Localization of Gh1 6 0.23 0 2.13
12 INT26948 Pomc Positive_regulation of Localization of Gh1 2 0.22 0.15 1.99
13 INT16891 GHRH Regulation of GH1 5 0.37 1.94 1.82
14 INT40827 Sstr1 Negative_regulation of Localization of Gh1 1 0.13 0 1.58
15 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
16 INT3573 Tf Negative_regulation of Localization of Gh1 1 0.36 0 1.49
17 INT19013 Ghsr Negative_regulation of Localization of Sst 1 0.15 0 1.44
18 INT19012 Ghsr Negative_regulation of Localization of Sstr1 1 0.10 0 1.44
19 INT34834 Ghrh Positive_regulation of Gene_expression of Gh1 2 0.65 0 1.4
20 INT26893 OGG1 Negative_regulation of Gh1 1 0.12 0 1.37
21 INT52568 HTR1D Regulation of Localization of Gh 2 0.20 0.16 1.34
22 INT142207 Adcyap1 Positive_regulation of Localization of Gh 1 0.07 0 1.3
23 INT48117 GH1 Positive_regulation of CGA 1 0.10 0 1.28
24 INT74467 Adcyap1 Positive_regulation of Localization of Gh1 1 0.37 0 1.25
25 INT70570 su Positive_regulation of Gh 1 0.01 0.15 1.24
26 INT32480 Gh1 Positive_regulation of Gene_expression of Ghrh 1 0.35 0 1.15
27 INT14199 GNRH1 Positive_regulation of Localization of Gh1 2 0.05 0 1.12
28 INT19887 GHRH Positive_regulation of Positive_regulation of GH1 2 0.56 0.3 1.08
29 INT14197 Pde2a Positive_regulation of Localization of Gh1 2 0.04 0 1.08
30 INT33338 Adarb1 Positive_regulation of Localization of Gh1 1 0.04 0 1.08
31 INT33336 Adarb1 Positive_regulation of Negative_regulation of Gh1 1 0.03 0 1.08
32 INT33337 Adarb1 Positive_regulation of Gh1 1 0.03 0 1.08
33 INT35157 GH1 Regulation of GHRH 3 0.17 0.5 0.99
34 INT41658 IL31RA Regulation of GH1 1 0.09 1.07 0.98
35 INT19758 Ghrh Positive_regulation of Positive_regulation of Gh 1 0.26 0 0.98
36 INT140068 Binding of GH1 and Ghsr 1 0.00 0.47 0.97
37 INT36682 Gh1 Regulation of Gene_expression of Gnrhr 2 0.08 0 0.96
38 INT36683 Gh1 Regulation of Gnrhr 3 0.08 1.25 0.95
39 INT31108 Ghrh Negative_regulation of Gh1 2 0.55 0 0.95
40 INT62106 Ghrh Negative_regulation of Localization of Gh 1 0.06 0 0.94
41 INT62109 SLC25A4 Negative_regulation of Localization of Gh 1 0.06 0 0.94
42 INT35252 Gene_expression of Ghrh Positive_regulation of Localization of Gh1 1 0.49 0 0.93
43 INT39201 Olr824 Positive_regulation of Localization of Gh1 1 0.03 0 0.91
44 INT48113 GH1 Positive_regulation of Localization of CGA 1 0.07 0 0.9
45 INT30411 Ghrh Regulation of Gene_expression of Gh1 1 0.40 0.12 0.9
46 INT35160 GH1 Regulation of PRL 2 0.37 0 0.89
47 INT61046 Oprm1 Positive_regulation of Gh1 1 0.21 0 0.89
48 INT61047 Oprm1 Positive_regulation of Localization of Gh1 1 0.29 0 0.89
49 INT28655 Calca Negative_regulation of Localization of Gh1 1 0.34 0 0.88
50 INT44589 Negative_regulation of Oprl1 Positive_regulation of Gh1 1 0.22 0.53 0.87
51 INT44590 Oprl1 Positive_regulation of Gh1 1 0.23 0.53 0.87
52 INT40742 Pomc Regulation of Localization of Gh1 1 0.37 0 0.86
53 INT132318 Ghrl Positive_regulation of Localization of GH1 5 0.32 4.49 0.84
54 INT105970 GH1 Regulation of Ghsr 1 0.04 1.16 0.84
55 INT28654 Calca Regulation of Localization of Gh1 1 0.36 0 0.84
56 INT5103 Gal Regulation of Localization of Gh1 1 0.33 0.08 0.82
57 INT54260 SST Regulation of GH1 1 0.18 0.06 0.81
58 INT90382 Binding of CRH and GH1 1 0.34 0.05 0.81
59 INT90381 Binding of GH1 and LAMC2 1 0.34 0.05 0.81
60 INT73775 Binding of GH1 and GHR 4 0.35 0.68 0.8
61 INT40743 Binding of Gh1 and Pomc 1 0.22 0 0.8
62 INT54800 Grin1 Regulation of Gene_expression of Gh 1 0.01 0 0.79
63 INT105250 Cyb5b Regulation of Localization of Gh1 1 0.00 0 0.79
64 INT92793 Gh Positive_regulation of CTS 1 0.04 1.39 0.78
65 INT142208 Adcyap1 Positive_regulation of Transcription of Gh 1 0.05 0 0.77
66 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
67 INT142210 Adcyap1 Positive_regulation of Gh 1 0.05 0 0.77
68 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
69 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
70 INT64067 Tp63 Negative_regulation of Localization of Gh1 1 0.08 0.07 0.76
71 INT152429 Ghrh Positive_regulation of Localization of Gh 4 0.37 0.56 0.75
72 INT73776 Regulation of Binding of GH1 and GHR 2 0.26 0.16 0.75
73 INT222528 Abat Positive_regulation of Gene_expression of Gh1 1 0.01 0 0.75
74 INT54802 SST Negative_regulation of Localization of Gh 1 0.01 0 0.75
75 INT54801 SST Negative_regulation of Positive_regulation of Gh 1 0.01 0 0.75
76 INT17528 Prl Regulation of Gh 2 0.28 1.28 0.73
77 INT16894 Regulation of GHRH Regulation of GH1 2 0.37 0 0.72
78 INT14196 Glra2 Positive_regulation of Localization of Gh1 1 0.06 0 0.71
79 INT31307 Ghrh Regulation of Gh1 3 0.27 1.36 0.7
80 INT30125 Binding of Gh and Ghrh 2 0.06 0.36 0.7
81 INT778 Tf Positive_regulation of Gh1 1 0.14 0 0.7
82 INT784 Prss12 Positive_regulation of Gh1 1 0.06 0 0.7
83 INT20688 Adra2a Regulation of Localization of Gh1 1 0.26 0.37 0.7
84 INT30409 Negative_regulation of Negative_regulation of Positive_regulation of Gh1 1 0.02 0.1 0.7
85 INT30408 Negative_regulation of Negative_regulation of Gh1 1 0.02 0.1 0.7
86 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69
87 INT34772 GH1 Regulation of IGF1 2 0.32 0.95 0.69
88 INT47264 Abat Regulation of Localization of Gh1 1 0.14 0 0.67
89 INT40471 GH1 Positive_regulation of POMC 1 0.25 0 0.67
90 INT40470 GH1 Positive_regulation of GHRH 1 0.06 0 0.67
91 INT222552 Abat Regulation of Gene_expression of Gh1 1 0.00 0 0.67
92 INT31260 Sst Negative_regulation of Gh1 2 0.11 0 0.66
93 INT103905 Gh Positive_regulation of Positive_regulation of Crh 1 0.08 0.9 0.66
94 INT45369 IGF1 Regulation of GH1 1 0.04 1.12 0.65
95 INT231534 Binding of JAK1 and SOAT1 1 0.01 0.6 0.64
96 INT142209 Adcyap1 Positive_regulation of Gene_expression of Gh 1 0.05 0 0.63
97 INT30502 Negative_regulation of OPRM1 Negative_regulation of Gh 1 0.00 0 0.63
98 INT3617 Trh Regulation of Localization of Gh1 3 0.65 0.55 0.62
99 INT15731 SST Regulation of Gh 1 0.04 0 0.62
100 INT19011 Binding of Ghrh and Ghsr 1 0.40 0 0.62
101 INT61507 Ghrhr Positive_regulation of Localization of Gh1 1 0.41 0 0.61
102 INT56520 DDX21 Positive_regulation of Localization of Gh 1 0.11 0.16 0.6
103 INT56391 Pomc Negative_regulation of Localization of Gh1 1 0.26 0 0.59
104 INT43692 Cyp3a23/3a1 Negative_regulation of Gh1 1 0.04 0 0.59
105 INT30462 Gnrhr Positive_regulation of Localization of Gh1 2 0.21 0.08 0.58
106 INT144864 Htr2b Positive_regulation of Localization of Gh1 1 0.48 0 0.58
107 INT156668 Gh Positive_regulation of Igf1 5 0.22 2.07 0.57
108 INT156667 Gh Positive_regulation of Gene_expression of Igf1 6 0.28 0.88 0.56
109 INT69566 Positive_regulation of Ghrh Regulation of Gh 1 0.04 1.66 0.55
110 INT32478 Gh1 Regulation of Gene_expression of Ghrh 1 0.28 0 0.55
111 INT316546 Binding of GH1 and SST 2 0.03 0.55 0.54
112 INT84067 IGFBP1 Regulation of GH1 1 0.02 1.18 0.54
113 INT29252 Regulation of INS Positive_regulation of GH1 1 0.26 0.08 0.54
114 INT142206 Negative_regulation of Adcyap1 Positive_regulation of Gh 1 0.04 0 0.54
115 INT29253 INS Positive_regulation of GH1 1 0.44 0.08 0.53
116 INT33513 GH1 Positive_regulation of PRL 1 0.30 0 0.53
117 INT49696 Trh Regulation of GH1 2 0.02 0.22 0.52
118 INT105971 GH1 Regulation of Ghrl 1 0.03 0.75 0.52
119 INT24869 GAL Regulation of Localization of Gh 1 0.19 0.4 0.51
120 INT32479 Gh1 Negative_regulation of Dbi 1 0.01 0 0.51
121 INT24205 Gh1 Negative_regulation of Gal 1 0.34 0 0.51
122 INT56671 Negative_regulation of Ghrh Positive_regulation of Gh1 1 0.40 0 0.49
123 INT140067 GH1 Positive_regulation of Ghsr 1 0.00 0.23 0.49
124 INT46051 ABAT Regulation of Localization of GH1 1 0.19 0 0.49
125 INT70930 Sstr2 Regulation of Localization of Gh1 1 0.15 0 0.49
126 INT36684 Gh1 Regulation of Prl 2 0.18 1.25 0.48
127 INT55020 Gh1 Regulation of Gene_expression of Prl 1 0.19 0 0.48
128 INT140066 Ghsr Positive_regulation of GH1 1 0.00 0.23 0.48
129 INT263977 PROC Negative_regulation of JAK2 1 0.00 0.93 0.47
130 INT134048 Jak2 Regulation of Pik3cb 1 0.23 0.13 0.47
131 INT134045 Jak2 Regulation of Stat3 1 0.26 0.13 0.47
132 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
133 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
134 INT134050 Positive_regulation of Jak2 Regulation of Stat3 1 0.44 0.13 0.47
135 INT47222 Binding of Gh and Prl 1 0.22 0.18 0.46
136 INT72203 GH1 Regulation of OGG1 1 0.10 0 0.46
137 INT47221 Prl Regulation of Localization of Gh 1 0.28 0.27 0.46
138 INT30412 Sst Regulation of Gene_expression of Gh1 1 0.19 0.06 0.45
139 INT48116 Negative_regulation of GH1 Positive_regulation of CGA 1 0.06 0 0.45
140 INT8181 Grm5 Positive_regulation of Gh 1 0.00 0 0.44
141 INT29254 Positive_regulation of ADRA2C Positive_regulation of Localization of GH1 1 0.13 0.06 0.44
142 INT325391 Binding of Ghrl and Ghsr 2 0.17 0.14 0.43
143 INT246024 IL23A Positive_regulation of SOCS2 1 0.01 0.99 0.43
144 INT246023 IL6 Positive_regulation of SOCS2 1 0.18 0.99 0.43
145 INT122237 Gnrh1 Positive_regulation of Gh1 1 0.20 0 0.43
146 INT40446 Cck Regulation of Gh1 1 0.36 0 0.43
147 INT86972 PDE1B Positive_regulation of Localization of Gh 1 0.00 0 0.42
148 INT64069 Sst Regulation of Localization of Gh1 1 0.10 0.1 0.42
149 INT3571 Sst Regulation of Negative_regulation of Gh1 1 0.24 0 0.42
150 INT222490 Npy Positive_regulation of Localization of Gh1 1 0.02 0.06 0.41
151 INT250531 Ghrh Regulation of Gh 1 0.22 0 0.41
152 INT16302 GHRH Regulation of Localization of GH1 1 0.65 0.62 0.4
153 INT62107 Ghrh Negative_regulation of Regulation of Gh 1 0.06 0 0.39
154 INT36812 Olr824 Positive_regulation of Gh1 1 0.04 0 0.39
155 INT237414 Binding of Jak2 and Bace1 1 0.20 0.77 0.39
156 INT99304 Igf1 Positive_regulation of Gh1 1 0.44 0.39 0.39
157 INT67553 Ghrh Positive_regulation of Regulation of Gh 1 0.04 0.55 0.39
158 INT62110 SLC25A4 Negative_regulation of Regulation of Gh 1 0.06 0 0.39
159 INT184092 Il11ra1 Positive_regulation of Jak1 1 0.17 0.3 0.39
160 INT234607 Socs3 Negative_regulation of JAK1 1 0.01 0.54 0.39
161 INT36814 Olr824 Regulation of Gh1 1 0.02 0 0.39
162 INT3634 Trh Regulation of Gh1 3 0.20 0.23 0.38
163 INT237369 SOAT1 Negative_regulation of Phosphorylation of JAK1 1 0.00 0 0.38
164 INT105772 SST Negative_regulation of Localization of GH1 1 0.10 0.54 0.38
165 INT48115 GH1 Positive_regulation of CGB 1 0.06 0 0.38
166 INT328819 Binding of Il6 and Jak1 1 0.08 0 0.38
167 INT328822 Binding of Jak1 and TYK2 1 0.11 0 0.38
168 INT30501 Sst Negative_regulation of Localization of Gh 1 0.01 0 0.38
169 INT328821 Binding of Il6st and Jak1 1 0.05 0 0.38
170 INT182497 IL1B Regulation of Localization of GH1 1 0.00 0.84 0.38
171 INT328828 Binding of Jak2 and Jak1 1 0.24 0 0.38
172 INT328827 Binding of Jak2 and Il6st 1 0.05 0 0.38
173 INT328820 Binding of Il6 and Jak2 1 0.09 0 0.38
174 INT78444 Binding of GH1 and IGF1 4 0.16 2.82 0.37
175 INT303994 Il6 Positive_regulation of JAK2 1 0.03 0.41 0.37
176 INT3616 Trh Positive_regulation of Localization of Gh1 4 0.73 0.49 0.36
177 INT16896 GHSR Regulation of GH1 2 0.23 0.24 0.36
178 INT35363 Binding of GH1 and GHRH 2 0.36 0.94 0.36
179 INT63277 Gpm6a Regulation of Gh1 1 0.01 0 0.36
180 INT16893 GHSR Positive_regulation of GH1 2 0.26 0.24 0.35
181 INT231535 Binding of JAK2 and SOAT1 1 0.01 0.3 0.35
182 INT84030 Regulation of Ghrh Positive_regulation of Gh 1 0.18 0 0.35
183 INT25526 Dst Regulation of Gh 1 0.00 0.26 0.34
184 INT8330 OPRD1 Regulation of Localization of GH1 1 0.19 0.17 0.33
185 INT254213 Binding of Jak1 and Tyk2 1 0.09 0.84 0.33
186 INT134324 Gh Regulation of Gene_expression of F8a 1 0.07 0 0.33
187 INT254217 Tyk2 Positive_regulation of Stat3 1 0.23 0.83 0.33
188 INT30418 Crh Negative_regulation of Localization of Gh1 1 0.41 0.72 0.33
189 INT254209 Jak1 Positive_regulation of Stat3 1 0.18 0.84 0.33
190 INT184084 Jak2 Positive_regulation of Stat1 1 0.33 0.3 0.33
191 INT184110 Jak1 Positive_regulation of Stat1 1 0.32 0.3 0.33
192 INT140493 GH1 Regulation of Prl 1 0.18 0.47 0.33
193 INT31182 Adra2a Regulation of Localization of Gh 1 0.01 0.35 0.32
194 INT243622 Twist1 Regulation of Jak2 1 0.30 0.2 0.32
195 INT30420 Crh Positive_regulation of Localization of Gh1 1 0.67 0.47 0.32
196 INT68482 Cga Regulation of Gh 1 0.00 1.89 0.31
197 INT1757 DDC Regulation of Localization of GH1 1 0.01 0 0.31
198 INT50307 Negative_regulation of GH1 Regulation of Gh1 1 0.00 0.07 0.31
199 INT50306 GH1 Regulation of Gh1 1 0.00 0.07 0.31
200 INT26065 GHRH Regulation of Regulation of GH1 1 0.11 0 0.3

Single Events

The table below shows the top 100 pain related interactions that have been reported for growth hormone receptor binding. They are ordered first by their pain relevance and then by number of times they were reported in growth hormone receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT876 Localization of Gh1 843 0.80 67.75 340.82
2 INT1893 Localization of Gh 1041 0.79 340.23 256.58
3 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18
4 INT880 Positive_regulation of Localization of Gh1 304 0.70 14.79 150.23
5 INT252 Localization of GH1 529 0.80 227.4 122.05
6 INT1530 Regulation of Gh 382 0.61 115.96 112.47
7 INT874 Positive_regulation of Gh1 244 0.70 27.17 97.98
8 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5
9 INT875 Regulation of Localization of Gh1 166 0.62 12.87 84.97
10 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91
11 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16
12 INT881 Negative_regulation of Localization of Gh1 164 0.58 15.1 75.28
13 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71
14 INT3161 Regulation of Localization of Gh 163 0.61 35.43 59.45
15 INT1782 Regulation of Gh1 125 0.62 22 55.74
16 INT1781 Negative_regulation of Gh1 127 0.59 16.94 51.77
17 INT921 Regulation of GH1 172 0.60 52.88 51.04
18 INT873 Gene_expression of Gh1 130 0.76 26.15 46.75
19 INT531 Gene_expression of GH1 376 0.75 193.45 46.24
20 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56
21 INT255 Regulation of Localization of GH1 89 0.62 18.71 35.3
22 INT248 Positive_regulation of Localization of GH1 137 0.69 49.25 32.92
23 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39
24 INT16303 Negative_regulation of Localization of GH1 89 0.59 37.31 22.15
25 INT13454 Positive_regulation of Positive_regulation of Gh 49 0.68 14.53 18.49
26 INT10841 Positive_regulation of Gene_expression of Gh 101 0.59 45.39 16.96
27 INT4242 Negative_regulation of Positive_regulation of Gh1 26 0.58 1.47 15.75
28 INT4298 Positive_regulation of Positive_regulation of Gh1 30 0.50 1.79 13.32
29 INT9678 Positive_regulation of Positive_regulation of GH1 32 0.68 8.14 12.97
30 INT11510 Negative_regulation of Positive_regulation of Gh 28 0.52 12.71 9.16
31 INT12292 Negative_regulation of Positive_regulation of GH1 22 0.58 5.02 8.28
32 INT1499 Negative_regulation of Gene_expression of Gh 58 0.42 25.17 7.86
33 INT34741 Positive_regulation of Gene_expression of GH1 58 0.67 35.06 7.8
34 INT4299 Positive_regulation of Gene_expression of Gh1 27 0.50 5.24 7.31
35 INT878 Regulation of Gene_expression of Gh1 13 0.43 1.13 6.98
36 INT28861 Binding of Gh 61 0.46 25.61 6.38
37 INT9683 Binding of GH1 57 0.47 21.14 5.99
38 INT10843 Regulation of Regulation of Gh 14 0.22 5.56 5.93
39 INT3614 Negative_regulation of Gene_expression of Gh1 16 0.42 6.8 5.74
40 INT13735 Negative_regulation of Regulation of GH1 14 0.42 4.35 5.39
41 INT18661 Localization of Ghsr 32 0.78 3.19 5.2
42 INT4611 Transcription of Gh1 12 0.68 1.04 4.97
43 INT113161 Gene_expression of Jak2 50 0.77 42.52 4.76
44 INT4378 Regulation of Gene_expression of GH1 26 0.47 10.2 4.61
45 INT16220 Negative_regulation of Regulation of Gh 13 0.42 3.59 4.33
46 INT10842 Transcription of Gh 18 0.64 2.94 4.13
47 INT153410 Negative_regulation of Jak2 5 0.59 10.71 3.98
48 INT19104 Regulation of Gene_expression of Gh 24 0.40 8.42 3.88
49 INT11605 Regulation of Positive_regulation of Gh 10 0.45 2.08 3.85
50 INT9677 Negative_regulation of Gene_expression of GH1 46 0.48 23.32 3.68
51 INT328808 Negative_regulation of Jak1 1 0.42 7.01 3.64
52 INT7365 Binding of Gh1 17 0.37 2.83 3.54
53 INT20179 Positive_regulation of Regulation of Gh 12 0.54 3.99 3.42
54 INT18407 Regulation of Regulation of GH1 6 0.44 0.14 3.37
55 INT118035 Positive_regulation of JAK1 23 0.67 10.57 3.29
56 INT13272 Regulation of Positive_regulation of Gh1 4 0.44 0.35 3.02
57 INT19009 Positive_regulation of Ghsr 17 0.64 5.71 2.78
58 INT919 Regulation of Positive_regulation of GH1 7 0.47 1.09 2.75
59 INT53906 Positive_regulation of Negative_regulation of Gh 9 0.50 6.72 2.73
60 INT113160 Negative_regulation of Jak2 26 0.58 20.3 2.57
61 INT113339 Binding of JAK2 6 0.40 5.31 2.4
62 INT184063 Positive_regulation of Jak2 17 0.69 10.97 2.37
63 INT20410 Regulation of Regulation of Gh1 5 0.30 0.66 2.36
64 INT153411 Positive_regulation of Jak1 3 0.49 1.24 2.25
65 INT35210 Gene_expression of Ghsr 39 0.75 6 2.24
66 INT4610 Negative_regulation of Transcription of Gh1 4 0.42 0.51 2.17
67 INT118871 Negative_regulation of JAK2 15 0.57 11.4 2.16
68 INT107448 Positive_regulation of Jak2 8 0.50 5.33 1.98
69 INT100689 Negative_regulation of JAK1 8 0.57 5.36 1.87
70 INT189839 Gene_expression of Jak1 2 0.50 0.51 1.87
71 INT1780 Regulation of Negative_regulation of Gh1 3 0.49 0.09 1.8
72 INT45719 Positive_regulation of Transcription of Gh 5 0.47 0.68 1.66
73 INT206144 Phosphorylation of JAK1 6 0.57 1.77 1.64
74 INT113340 Phosphorylation of JAK2 17 0.78 5.69 1.6
75 INT19007 Binding of Ghsr 5 0.46 0.46 1.6
76 INT153409 Negative_regulation of Negative_regulation of Jak2 2 0.34 1.01 1.52
77 INT106574 Phosphorylation of Jak1 2 0.60 0.35 1.5
78 INT16528 Positive_regulation of Regulation of Gh1 5 0.48 0.37 1.47
79 INT65892 Negative_regulation of Binding of Gh 8 0.32 3.61 1.38
80 INT134041 Phosphorylation of Jak2 6 0.75 3.71 1.37
81 INT155846 Transcription of JAK1 4 0.67 1.93 1.19
82 INT57852 Regulation of Ghsr 15 0.59 1.02 1.1
83 INT47495 Protein_catabolism of Gh 2 0.98 0.68 1.08
84 INT142205 Negative_regulation of Transcription of Gh 1 0.16 0 1.08
85 INT205912 Negative_regulation of Gene_expression of Jak2 8 0.42 5.1 1.04
86 INT198049 Positive_regulation of JAK2 16 0.58 5.35 0.96
87 INT62246 Positive_regulation of Transcription of Gh1 1 0.26 0 0.94
88 INT169336 Binding of Jak2 2 0.42 1.31 0.93
89 INT134040 Regulation of Jak2 3 0.41 1.07 0.92
90 INT55982 Negative_regulation of Negative_regulation of Gh 4 0.55 1.02 0.88
91 INT184027 Phosphorylation of Jak2 6 0.82 2.58 0.87
92 INT7867 Regulation of Negative_regulation of Gh 5 0.33 1.92 0.87
93 INT205906 Negative_regulation of Gene_expression of Jak1 1 0.32 0.47 0.87
94 INT73784 Regulation of Binding of GH1 2 0.26 0.82 0.86
95 INT134037 Positive_regulation of Phosphorylation of Jak2 1 0.46 0.25 0.86
96 INT134038 Positive_regulation of Phosphorylation of Jak1 1 0.50 0.25 0.86
97 INT3560 Negative_regulation of Regulation of Gh1 5 0.40 2.44 0.85
98 INT238201 Gene_expression of JAK2 9 0.70 7.09 0.81
99 INT237408 Positive_regulation of Positive_regulation of Jak2 1 0.28 1.56 0.79
100 INT113342 Positive_regulation of Phosphorylation of JAK2 2 0.66 2.58 0.72
101 INT35208 Positive_regulation of Negative_regulation of Gh1 3 0.49 0.08 0.7
102 INT70362 Transcription of GH1 9 0.56 2.01 0.69
103 INT186276 Phosphorylation of Jak1 4 0.58 0.65 0.68
104 INT184016 Negative_regulation of Jak1 4 0.32 0.68 0.68
105 INT17698 Positive_regulation of Regulation of GH1 6 0.46 0.9 0.65
106 INT328809 Binding of Jak1 1 0.35 0.32 0.65
107 INT106569 Regulation of Jak1 1 0.06 0.1 0.65
108 INT47563 Negative_regulation of Negative_regulation of Gh1 3 0.41 0.7 0.64
109 INT184030 Gene_expression of Socs2 8 0.74 3.54 0.63
110 INT167712 Positive_regulation of Positive_regulation of Jak1 1 0.23 0.57 0.63
111 INT205901 Positive_regulation of Gene_expression of Jak1 1 0.35 0 0.56
112 INT184036 Positive_regulation of Jak1 5 0.45 2.25 0.55
113 INT264129 Protein_catabolism of JAK1 1 0.02 0.38 0.55
114 INT19005 Positive_regulation of Positive_regulation of Ghsr 1 0.49 0 0.53
115 INT184038 Negative_regulation of Socs2 5 0.31 1.68 0.51
116 INT226580 Localization of JAK1 3 0.11 0.52 0.49
117 INT184062 Binding of Jak2 5 0.37 3.13 0.47
118 INT263240 Regulation of Socs2 2 0.02 0.96 0.46
119 INT184025 Binding of Jak1 2 0.21 0.84 0.46
120 INT205890 Transcription of Jak2 1 0.41 0.22 0.43
121 INT205895 Positive_regulation of Transcription of Jak1 1 0.35 0.22 0.43
122 INT87505 Positive_regulation of Binding of Gh 2 0.49 0 0.42
123 INT205885 Transcription of Jak1 1 0.40 0.21 0.42
124 INT145854 Gene_expression of Jak2 4 0.67 3.08 0.41
125 INT107462 Localization of Jak2 2 0.60 0.78 0.4
126 INT229697 Negative_regulation of Phosphorylation of Jak2 1 0.15 0.54 0.39
127 INT279298 Gene_expression of JAK1 7 0.65 5.5 0.37
128 INT280551 Negative_regulation of Gene_expression of JAK1 2 0.41 1.02 0.37
129 INT78447 Protein_catabolism of GH1 2 0.36 1.2 0.36
130 INT200786 Positive_regulation of Gene_expression of Jak2 9 0.69 6.03 0.35
131 INT205910 Negative_regulation of Positive_regulation of Jak2 1 0.33 0.26 0.35
132 INT317742 Positive_regulation of Transcription of JAK1 1 0.49 0.57 0.35
133 INT240525 Positive_regulation of Tyk2 2 0.25 0.99 0.34
134 INT7359 Regulation of Binding of Gh1 1 0.33 0.13 0.34
135 INT188281 Transcription of Ghsr 1 0.66 0.8 0.34
136 INT184076 Binding of Socs2 1 0.33 0.8 0.29
137 INT215028 Phosphorylation of Gh 3 0.56 2.11 0.28
138 INT188353 Positive_regulation of Socs2 2 0.49 0.38 0.27
139 INT280561 Binding of JAK1 2 0.26 0.39 0.26
140 INT303972 Positive_regulation of Gene_expression of JAK2 2 0.63 1.3 0.24
141 INT98692 Negative_regulation of Regulation of Ghsr 2 0.21 0.15 0.24
142 INT328815 Regulation of Negative_regulation of Jak1 1 0.32 0.88 0.24
143 INT83747 Regulation of Gene_expression of Ghsr 2 0.26 0.27 0.21
144 INT258447 Positive_regulation of TYK2 1 0.21 1.27 0.21
145 INT240528 Phosphorylation of Tyk2 1 0.44 0.74 0.21
146 INT57851 Regulation of Regulation of Ghsr 1 0.04 0 0.19
147 INT27561 Negative_regulation of Negative_regulation of GH1 2 0.15 0.38 0.18
148 INT328811 Negative_regulation of Localization of Jak2 1 0.34 0.13 0.17
149 INT27856 Positive_regulation of Phosphorylation of GH1 1 0.18 0 0.17
150 INT200802 Regulation of Jak2 5 0.61 2.86 0.16
151 INT65898 Negative_regulation of Ghsr 3 0.26 2.01 0.16
152 INT27855 Phosphorylation of GH1 2 0.61 0 0.16
153 INT328810 Positive_regulation of Negative_regulation of Jak1 1 0.36 0.16 0.15
154 INT306281 Gene_expression of SOCS2 1 0.01 0.52 0.14
155 INT90672 Regulation of Binding of Gh 3 0.56 1.07 0.13
156 INT278143 Positive_regulation of Negative_regulation of Jak2 1 0.16 0.54 0.11
157 INT98804 Negative_regulation of Transcription of GH1 2 0.35 0.7 0.1
158 INT261158 Positive_regulation of Gene_expression of Socs2 2 0.08 0.13 0.1
159 INT293340 Negative_regulation of Negative_regulation of JAK1 1 0.02 0.34 0.1
160 INT312354 Regulation of Gene_expression of JAK2 1 0.25 1.17 0.1
161 INT200792 Regulation of Gene_expression of Jak2 5 0.61 5.69 0.09
162 INT325417 Regulation of Positive_regulation of Ghsr 1 0.41 0.1 0.09
163 INT184018 Negative_regulation of Protein_catabolism of Jak2 1 0.36 1.76 0.08
164 INT184023 Protein_catabolism of Jak2 1 0.61 1.75 0.08
165 INT239094 Negative_regulation of Binding of GH1 2 0.34 1.61 0.06
166 INT98805 Positive_regulation of Negative_regulation of GH1 2 0.36 1.43 0.06
167 INT310747 Regulation of JAK2 2 0.33 1.58 0.05
168 INT238202 Negative_regulation of Localization of JAK2 1 0.09 0 0.05
169 INT244286 Gene_expression of Jak1 1 0.65 0.09 0.05
170 INT238200 Localization of JAK2 1 0.16 0 0.05
171 INT300102 Gene_expression of TYK2 1 0.29 2.34 0.05
172 INT76597 Positive_regulation of Gene_expression of Ghsr 7 0.63 2.51 0.03
173 INT188284 Negative_regulation of Gene_expression of Ghsr 2 0.41 0.17 0.03
174 INT238199 Positive_regulation of Positive_regulation of JAK2 1 0.10 0 0.03
175 INT220373 Positive_regulation of Binding of Gh1 1 0.10 0.38 0.03
176 INT300109 Positive_regulation of Phosphorylation of TYK2 1 0.24 1.14 0
177 INT280557 Negative_regulation of Binding of JAK1 1 0.30 0.4 0
178 INT206164 Positive_regulation of Phosphorylation of JAK1 1 0.19 0.19 0
179 INT238196 Negative_regulation of Binding of JAK2 1 0.09 0 0
180 INT280558 Positive_regulation of Binding of JAK1 1 0.35 0.39 0
181 INT315883 Positive_regulation of Positive_regulation of JAK1 1 0.01 0.38 0
182 INT144040 Negative_regulation of Positive_regulation of JAK1 1 0.04 0.08 0
183 INT202420 Transcription of Jak2 1 0.56 0.91 0
184 INT350506 Protein_catabolism of JAK2 1 0.48 1.55 0
185 INT320539 Negative_regulation of Phosphorylation of JAK2 1 0.26 0.46 0
186 INT300094 Phosphorylation of TYK2 1 0.39 1.07 0
187 INT222599 Protein_catabolism of Gh1 1 0.08 0.49 0
188 INT230978 Positive_regulation of SOCS2 1 0.23 0.08 0
189 INT76598 Positive_regulation of Localization of Ghsr 1 0.45 0 0
190 INT300097 Binding of TYK2 1 0.23 1.13 0
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