GO:0005134

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Name interleukin-2 receptor binding
Categary Function
Go Slim No
Go Link GO:0005134
Unique Molecular Interactions 436
Total Molecular Interactions 539
Total Single Events 5982
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for interleukin-2 receptor binding. They are ordered first by their pain relevance and then by number of times they were reported for interleukin-2 receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT62450 Il2 Positive_regulation of Localization of Crh 1 0.43 0.59 2.64
2 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
3 INT21536 Binding of Il2 and Il1 1 0.28 0 1.47
4 INT86172 Pdyn Positive_regulation of Gene_expression of Il2 1 0.20 0 1.33
5 INT62448 Il2 Positive_regulation of Crh 1 0.59 0.36 1.3
6 INT89943 Binding of Oprm1 and Il2 1 0.03 0.53 1.28
7 INT329956 Binding of IL2 and IL23R 1 0.33 4.58 1.21
8 INT142154 Trpv1 Positive_regulation of Gene_expression of Il2 1 0.22 0 1.21
9 INT88193 Binding of IL2 and IL4 1 0.13 1.7 1.2
10 INT88614 Penk Negative_regulation of Il2 1 0.23 0 1.08
11 INT54501 beta-End6-31 Positive_regulation of Gene_expression of Il2 1 0.03 0 1.06
12 INT21415 POMC Positive_regulation of Gene_expression of IL2 1 0.00 0.27 1
13 INT94501 Il2 Positive_regulation of Gene_expression of Ifng 1 0.03 1.63 0.92
14 INT213977 Pax3 Negative_regulation of Gene_expression of Il2 1 0.00 0.25 0.86
15 INT213976 Calca Negative_regulation of Gene_expression of Il2 1 0.03 0.25 0.86
16 INT161306 POMC Negative_regulation of Transcription of IL2 1 0.24 0.27 0.85
17 INT161307 JUN Positive_regulation of IL2 1 0.14 0.25 0.84
18 INT161305 NFKB1 Positive_regulation of IL2 1 0.25 0.25 0.83
19 INT12883 Binding of IL2 and POMC 1 0.01 0 0.81
20 INT53199 Positive_regulation of Cd4 Positive_regulation of Gene_expression of Il2 1 0.52 0.72 0.8
21 INT8411 IL2 Regulation of Gene_expression of Vip 1 0.00 0.27 0.8
22 INT209035 Il2 Positive_regulation of Ccr1 1 0.00 0.38 0.73
23 INT21535 Binding of Il2 and Il1f5 1 0.13 0 0.73
24 INT209052 Il2 Positive_regulation of Il17a 1 0.03 0.38 0.73
25 INT209053 Il2 Positive_regulation of Elf1 1 0.06 0.38 0.73
26 INT209036 Il2 Positive_regulation of Cxcl1 1 0.04 0.38 0.73
27 INT209051 Il2 Positive_regulation of Csf2 1 0.02 0.38 0.73
28 INT266769 IL2 Positive_regulation of Localization of IL4 1 0.00 1.03 0.72
29 INT266765 IL2 Positive_regulation of Localization of IL10 1 0.01 1.03 0.72
30 INT27034 HERPUD1 Regulation of Gene_expression of IL2 1 0.38 0 0.71
31 INT151681 Il2 Negative_regulation of Art2a-ps 1 0.00 1.23 0.7
32 INT151678 Il2 Negative_regulation of Oas1b 1 0.13 1.23 0.7
33 INT54502 Pomc Positive_regulation of Gene_expression of Il2 1 0.16 0 0.68
34 INT250871 Il1a Positive_regulation of Protein_catabolism of Ecm1 1 0.01 1.44 0.68
35 INT56308 POMC Negative_regulation of Gene_expression of Il2 1 0.01 0.1 0.67
36 INT82382 Penk Positive_regulation of Gene_expression of Il2 1 0.10 0 0.66
37 INT72504 IgG Negative_regulation of Il2 1 0.37 0 0.65
38 INT243639 Twist1 Negative_regulation of Gene_expression of Il2 1 0.24 1.28 0.65
39 INT86171 Oprl1 Positive_regulation of Gene_expression of Il2 1 0.30 0 0.64
40 INT179850 Binding of Ecm1 and Il11 1 0.02 0 0.6
41 INT329963 Binding of IL21 and IL23R 1 0.30 2.28 0.6
42 INT13238 POMC Regulation of Gene_expression of IL2 1 0.09 0.26 0.59
43 INT60375 Il2 Regulation of Localization of Penk 1 0.03 0 0.59
44 INT74656 YY1 Positive_regulation of Localization of IL2 1 0.07 0.09 0.58
45 INT60374 Il2 Positive_regulation of Pomc 1 0.07 0 0.58
46 INT60372 Il2 Positive_regulation of Localization of Pomc 1 0.08 0 0.58
47 INT60373 Il2 Positive_regulation of Localization of Penk 1 0.52 0 0.58
48 INT39210 TF Positive_regulation of Gene_expression of IL2 1 0.17 0.07 0.57
49 INT141362 EP300 Negative_regulation of Transcription of IL2 1 0.17 0 0.56
50 INT144598 Hrh2 Positive_regulation of IL2 1 0.01 0.08 0.56
51 INT250852 Fgf8 Negative_regulation of Gene_expression of Ecm1 1 0.04 1.1 0.54
52 INT184088 Epo Positive_regulation of Il2 1 0.07 0.26 0.52
53 INT184132 Il2 Positive_regulation of Stat5a 1 0.09 0.26 0.51
54 INT32597 Pomc Regulation of Gene_expression of Il2 1 0.29 0 0.49
55 INT250858 Mmp3 Regulation of Protein_catabolism of Ecm1 1 0.01 1.11 0.47
56 INT306732 Il17a Positive_regulation of Gene_expression of Il2 1 0.09 1.07 0.46
57 INT175788 Il2 Positive_regulation of Localization of Avp 1 0.03 0.41 0.46
58 INT306731 Il22 Positive_regulation of Gene_expression of Il2 1 0.12 1.07 0.46
59 INT292627 IL21 Positive_regulation of IL4 1 0.10 0.41 0.42
60 INT95206 Binding of CSF2 and IL2 1 0.40 1.81 0.4
61 INT292891 IL2 Regulation of IL5 1 0.02 0.25 0.39
62 INT260744 Binding of Ecm1 and Tlr2 1 0.00 0.45 0.39
63 INT292889 IL2 Regulation of IL12A 1 0.01 0.25 0.39
64 INT300547 Il6 Positive_regulation of Il21 1 0.02 0.78 0.39
65 INT292886 IL2 Regulation of IL8 1 0.03 0.25 0.39
66 INT260746 Binding of TLR4 and Ecm1 1 0.02 0.44 0.38
67 INT250870 Fgf8 Positive_regulation of Ecm1 1 0.04 0.79 0.38
68 INT172148 Binding of IL2 and TNF 2 0.05 0.67 0.37
69 INT172135 Binding of IL2 and IL6 1 0.01 0.57 0.37
70 INT27036 HERPUD1 Positive_regulation of Gene_expression of IL2 1 0.31 0 0.37
71 INT68119 Binding of IL2 and Oprd1 1 0.02 0 0.37
72 INT70924 Binding of Il2 and Il4 1 0.07 0.34 0.36
73 INT27032 ASNA1 Regulation of Gene_expression of IL2 1 0.03 0 0.36
74 INT320699 Gene_expression of Ptger2 Negative_regulation of Gene_expression of IL2 1 0.00 1.1 0.35
75 INT320694 C5 Regulation of Gene_expression of Il2 1 0.03 2.15 0.34
76 INT267589 IL2 Positive_regulation of Gene_expression of IL12A 1 0.01 0.69 0.34
77 INT39208 ALOX5 Regulation of Gene_expression of IL2 1 0.04 0.06 0.34
78 INT285565 Positive_regulation of Zeb1 Negative_regulation of IL2 1 0.02 0.62 0.33
79 INT206609 Binding of Col7a1 and Ecm1 1 0.00 0.47 0.33
80 INT206608 Binding of Ecm1 and Itgb5 1 0.02 0.41 0.33
81 INT285566 F8 Negative_regulation of IL2 1 0.00 0.62 0.33
82 INT285563 Zeb1 Negative_regulation of IL2 1 0.01 0.62 0.33
83 INT303993 Lep Positive_regulation of Gene_expression of IL2 1 0.15 0.24 0.33
84 INT34727 TNF Positive_regulation of Gene_expression of IL2 1 0.56 0.81 0.31
85 INT94076 ARSA Negative_regulation of Gene_expression of IL2 1 0.13 0.09 0.3
86 INT94072 ARSA Regulation of Gene_expression of IL2 1 0.07 0.09 0.29
87 INT62753 IL2 Regulation of POMC 1 0.27 0 0.28
88 INT19513 Prl Positive_regulation of IL2 1 0.41 0.8 0.27
89 INT68118 Binding of IL2 and OPRD1 1 0.35 0 0.26
90 INT189145 MTNR1B Positive_regulation of Gene_expression of IL2 1 0.02 0.3 0.26
91 INT351007 Binding of IL2 and IL2RA 1 0.33 1.33 0.26
92 INT212568 Fst Regulation of Gene_expression of Il2 1 0.30 0.07 0.24
93 INT298993 Il2 Positive_regulation of Gene_expression of Il13 1 0.01 0.73 0.24
94 INT331087 Csf2 Positive_regulation of Gene_expression of Il2 1 0.00 0.22 0.24
95 INT307011 MT1JP Regulation of IL2 1 0.01 0 0.24
96 INT63196 INS Positive_regulation of IL2 1 0.10 0.3 0.23
97 INT63197 POMC Positive_regulation of IL2 1 0.16 0.3 0.23
98 INT164517 CABIN1 Positive_regulation of Transcription of IL2 1 0.13 0.35 0.22
99 INT180670 Cpd Regulation of Protein_catabolism of Ecm1 1 0.04 0.14 0.22
100 INT63200 PTH Positive_regulation of IL2 1 0.24 0.29 0.22
101 INT318303 Negative_regulation of Myoz1 Negative_regulation of Transcription of IL2 1 0.00 0.75 0.21
102 INT141043 ZNF404 Negative_regulation of Transcription of IL2 1 0.01 0 0.21
103 INT299787 Binding of IL2 and ISG20 1 0.04 0.82 0.21
104 INT39209 TMSB4XP5 Positive_regulation of Gene_expression of IL2 1 0.07 0 0.21
105 INT62451 Il2 Regulation of Localization of Crh 1 0.53 0.19 0.2
106 INT226333 IL21 Positive_regulation of Binding of STAT4 1 0.03 0.57 0.2
107 INT34903 CALM1 Negative_regulation of Gene_expression of IL2 1 0.18 0 0.2
108 INT226528 BTPs Negative_regulation of Gene_expression of IL2 1 0.04 0.22 0.19
109 INT292625 IL2 Positive_regulation of Gene_expression of IL9 1 0.11 0.29 0.19
110 INT226346 Binding of IL21 and Positive_regulation of Positive_regulation of JAK3 1 0.08 0.48 0.18
111 INT193695 Il2 Positive_regulation of Ctla4 1 0.01 1.63 0.18
112 INT52790 D5Nam12 Regulation of Localization of Il2 1 0.01 0 0.18
113 INT65744 Map3k7 Negative_regulation of Gene_expression of Il2 1 0.10 0.74 0.18
114 INT353037 IL4 Positive_regulation of IL2 1 0.02 0.99 0.16
115 INT303980 Lep Positive_regulation of Transcription of IL2 1 0.10 0.24 0.16
116 INT353038 IL4 Positive_regulation of Localization of IL2 1 0.02 0.99 0.16
117 INT226359 IL21 Negative_regulation of Gene_expression of IGHE 1 0.02 0.79 0.16
118 INT194829 Gata3 Positive_regulation of IL13 1 0.01 0.12 0.15
119 INT211310 Trav6-3 Positive_regulation of Positive_regulation of Il2 1 0.02 0.2 0.15
120 INT194835 Gata3 Positive_regulation of IL5 1 0.01 0.12 0.15
121 INT194833 Binding of IL5 and Gata3 1 0.01 0.12 0.15
122 INT289248 Il6 Positive_regulation of Gene_expression of Il21 1 0.06 0.69 0.15
123 INT259628 Cxcl10 Positive_regulation of Protein_catabolism of Ecm1 1 0.00 0.64 0.15
124 INT194827 Binding of IL13 and Gata3 1 0.01 0.12 0.15
125 INT302826 Negative_regulation of Binding of Il2 and Kit 1 0.01 1.28 0.14
126 INT302827 Binding of Il2 and Kit 1 0.01 1.27 0.14
127 INT315492 Hspg2 Negative_regulation of Gene_expression of Il2 1 0.06 0.14 0.14
128 INT49608 IL2 Positive_regulation of Alpk1 1 0.01 1.47 0.14
129 INT252336 Il2 Positive_regulation of Akt1 1 0.01 0 0.13
130 INT215010 Myoz1 Positive_regulation of Gene_expression of Il2 1 0.05 0.13 0.13
131 INT250857 Gene_expression of Mmp3 Positive_regulation of Protein_catabolism of Ecm1 1 0.01 0.17 0.13
132 INT338428 Il4 Positive_regulation of Gata3 1 0.06 0.75 0.13
133 INT250869 Mia Positive_regulation of Protein_catabolism of Ecm1 1 0.01 0.25 0.12
134 INT292630 IL21 Positive_regulation of Gene_expression of IL9 1 0.15 0.15 0.12
135 INT289793 Binding of Comp and Ecm1 1 0.05 2.5 0.12
136 INT289958 Binding of IL2 and IL2RB 1 0.02 0.59 0.12
137 INT37134 Il2 Regulation of Ril 1 0.22 0.31 0.12
138 INT336632 Ecm1 Regulation of Regulation of Ahr 1 0.03 0.61 0.11
139 INT299782 Cd28 Regulation of Gene_expression of Il2 1 0.01 0.43 0.11
140 INT299781 Cd80 Regulation of Gene_expression of Il2 1 0.01 0.43 0.11
141 INT39207 LBR Positive_regulation of Gene_expression of IL2 1 0.23 0 0.11
142 INT352030 Binding of NR3C1 and IL2 1 0.15 0.5 0.11
143 INT286969 IL2 Regulation of Gene_expression of FOXP3 1 0.04 1.05 0.1
144 INT253074 Prok2 Regulation of Gene_expression of Il2 1 0.09 0.15 0.1
145 INT315490 Hspg2 Negative_regulation of Il2 1 0.08 0 0.09
146 INT324829 ROS1 Positive_regulation of Gene_expression of Ecm1 1 0.00 0.66 0.09
147 INT333095 Localization of IL2 Negative_regulation of Negative_regulation of CD8A 1 0.10 0.8 0.09
148 INT194730 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of IL2 1 0.06 0 0.09
149 INT33809 IL2 Regulation of Regulation of LIPE 1 0.23 0.09 0.09
150 INT333099 Localization of IL2 Negative_regulation of Negative_regulation of CD4 1 0.14 0.8 0.09
151 INT348686 Plg Positive_regulation of Protein_catabolism of Ecm1 1 0.02 0.17 0.09
152 INT324828 ELANE Positive_regulation of Localization of Ecm1 1 0.00 0.61 0.09
153 INT33806 IL2 Regulation of ADRB3 1 0.28 0.08 0.09
154 INT336634 Fbln1 Positive_regulation of Ecm1 1 0.06 1.26 0.09
155 INT226044 Lta Positive_regulation of Ecm1 1 0.02 0.44 0.08
156 INT296041 Binding of TGFB1 and IL21 1 0.01 0.05 0.08
157 INT259622 Elane Positive_regulation of Protein_catabolism of Ecm1 1 0.00 0.38 0.08
158 INT296035 IL21 Positive_regulation of Gene_expression of IL23R 1 0.01 0.05 0.08
159 INT179847 Binding of Ecm1 and Sparc 1 0.04 0 0.08
160 INT318074 Polr1a Negative_regulation of Gene_expression of Il2 1 0.00 0.46 0.08
161 INT159852 Gene_expression of IL2 Regulation of Gene_expression of ACTN1 1 0.03 0.16 0.07
162 INT278059 XRCC1 Positive_regulation of Gene_expression of IL2 1 0.01 1.06 0.07
163 INT159854 Gene_expression of IL2 Regulation of Gene_expression of CDC42EP5 1 0.01 0.16 0.07
164 INT182897 Mak Positive_regulation of Gene_expression of Il2 1 0.38 0.09 0.07
165 INT33807 IL2 Negative_regulation of Negative_regulation of LIPE 1 0.16 0.06 0.07
166 INT192407 Col7a1 Positive_regulation of Gene_expression of Il2 1 0.01 0.09 0.07
167 INT333092 Binding of CD4 and IL2 1 0.01 0.17 0.07
168 INT159853 Gene_expression of IL2 Regulation of Gene_expression of RHO 1 0.17 0.16 0.07
169 INT333098 Binding of CD8A and IL2 1 0.01 0.17 0.07
170 INT292629 IL21 Positive_regulation of IL12A 1 0.06 0.05 0.06
171 INT215006 Myoz1 Regulation of Transcription of Il2 1 0.06 0.44 0.06
172 INT159851 Positive_regulation of RHOA Positive_regulation of Gene_expression of IL2 1 0.15 0.15 0.06
173 INT286966 IL2 Positive_regulation of Binding of STAT3 1 0.04 0.5 0.06
174 INT292624 IL21 Positive_regulation of Binding of IL12A 1 0.06 0.05 0.06
175 INT194678 IL2 Positive_regulation of Positive_regulation of MAPK1 1 0.05 0 0.06
176 INT194664 Negative_regulation of MAPK1 Negative_regulation of IL2 1 0.06 0 0.05
177 INT179852 Binding of PTPRC and Ecm1 1 0.00 0 0.05
178 INT60089 IL2 Regulation of IFNA2 1 0.25 0.09 0.05
179 INT351010 ISG20 Positive_regulation of Transcription of IL2 1 0.31 0.46 0.05
180 INT226043 Epo Positive_regulation of Ecm1 1 0.04 1.35 0.05
181 INT336388 Binding of IL2 and ALPK1 1 0.06 0.73 0.05
182 INT351009 IL2RG Positive_regulation of Transcription of IL2 1 0.27 0.44 0.05
183 INT351008 IL2RB Positive_regulation of Gene_expression of IL2 1 0.18 0.42 0.05
184 INT25399 Il2 Positive_regulation of Gene_expression of Csf2 1 0.41 0.07 0.05
185 INT268674 IL2 Positive_regulation of XRCC1 1 0.08 0.75 0.05
186 INT180667 Edn1 Regulation of Ecm1 1 0.04 0 0.05
187 INT182098 Binding of IL8 and Il2 1 0.00 0 0.04
188 INT194694 MAPK1 Negative_regulation of Gene_expression of IL2 1 0.04 0 0.04
189 INT331172 Binding of IFNA1 and IL2 1 0.00 0.46 0.04
190 INT299762 Binding of Cd28 and Positive_regulation of Gene_expression of Il2 1 0.03 0.07 0.04
191 INT179836 Il11 Regulation of Gene_expression of Ecm1 1 0.05 0 0.04
192 INT227333 Il2 Positive_regulation of Hmox1 1 0.05 0.93 0.04
193 INT182099 Binding of TNF and Il2 1 0.01 0 0.04
194 INT265226 Binding of IFN1@ and Il2 1 0.07 0.19 0.04
195 INT182095 Binding of Il2 and Il6 1 0.01 0 0.04
196 INT35172 IL2 Positive_regulation of Gene_expression of IFNG 1 0.01 0.27 0.04
197 INT120449 Pparg Positive_regulation of Negative_regulation of Il2 1 0.75 0 0.04
198 INT176326 IL2 Positive_regulation of Gene_expression of MUC1 1 0.08 0.71 0.04
199 INT336639 PTPRC Positive_regulation of Ecm1 1 0.00 0.62 0.04
200 INT219230 Binding of Ecm1 and Ighv10-3 1 0.00 0.26 0.04

Single Events

The table below shows the top 100 pain related interactions that have been reported for interleukin-2 receptor binding. They are ordered first by their pain relevance and then by number of times they were reported in interleukin-2 receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69
2 INT11807 Gene_expression of Il2 266 0.78 112 64.97
3 INT12345 Gene_expression of Il2 142 0.78 59.17 51.21
4 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67
5 INT10763 Localization of IL2 157 0.80 81.11 33.21
6 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7
7 INT9993 Positive_regulation of Gene_expression of IL2 131 0.69 46.27 30.04
8 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96
9 INT11804 Positive_regulation of Gene_expression of Il2 70 0.70 33 21.63
10 INT15796 Regulation of IL2 66 0.61 25.43 20.62
11 INT11803 Positive_regulation of Il2 62 0.70 31.44 18.93
12 INT21532 Negative_regulation of Gene_expression of Il2 47 0.59 20.43 16.96
13 INT10000 Regulation of Gene_expression of IL2 56 0.45 15.33 16.2
14 INT22098 Positive_regulation of Il2 27 0.69 14.77 14.1
15 INT20381 Localization of Il2 71 0.77 34.23 13.03
16 INT51014 Transcription of IL2 42 0.71 21.56 12.7
17 INT32595 Positive_regulation of Gene_expression of Il2 30 0.70 6.55 12.56
18 INT14334 Negative_regulation of Il2 31 0.58 18.63 11.08
19 INT12344 Negative_regulation of Gene_expression of Il2 28 0.59 15.53 10.23
20 INT22383 Binding of IL2 59 0.48 39.06 8.56
21 INT32596 Regulation of Gene_expression of Il2 13 0.61 6.85 7.83
22 INT62452 Regulation of Il2 14 0.61 12.11 7.64
23 INT224648 Gene_expression of Il21 15 0.39 18.71 7.47
24 INT70814 Negative_regulation of Il2 40 0.56 13.36 7.22
25 INT134967 Gene_expression of Ecm1 66 0.29 38.4 7.16
26 INT25385 Positive_regulation of Localization of Il2 17 0.45 9.53 6.45
27 INT171691 Protein_catabolism of Ecm1 31 0.20 11.57 6.38
28 INT179810 Protein_catabolism of Ecm1 30 0.11 18.28 5.75
29 INT12066 Localization of Il2 16 0.75 3.06 5.7
30 INT11805 Regulation of Gene_expression of Il2 19 0.62 6.62 5.2
31 INT59320 Transcription of Il2 32 0.69 6.39 4.95
32 INT58459 Negative_regulation of Localization of IL2 13 0.41 6.46 4.88
33 INT134968 Localization of Ecm1 20 0.32 27.27 4.31
34 INT116011 Positive_regulation of Gata3 5 0.31 3.17 4.21
35 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12
36 INT29138 Positive_regulation of Localization of IL2 25 0.50 10.06 3.89
37 INT92678 Positive_regulation of Ecm1 30 0.09 28.41 3.68
38 INT132187 Gene_expression of Ecm1 14 0.21 8.12 3.52
39 INT171233 Binding of Ecm1 25 0.07 12.41 3.36
40 INT11815 Regulation of Il2 16 0.59 4.81 2.83
41 INT22831 Negative_regulation of Positive_regulation of IL2 7 0.55 1.7 2.62
42 INT202419 Positive_regulation of Gene_expression of Gata3 6 0.52 5.47 2.6
43 INT141367 Negative_regulation of Transcription of IL2 9 0.32 2.07 2.43
44 INT134964 Regulation of Ecm1 13 0.10 7.45 2.37
45 INT160080 Localization of Ecm1 6 0.15 4.86 2.36
46 INT25382 Binding of Il2 16 0.37 11.69 2.32
47 INT72531 Binding of Il2 2 0.48 0.18 2.32
48 INT20289 Regulation of Localization of IL2 7 0.26 1.23 2.24
49 INT224636 Positive_regulation of Il21 6 0.45 6.16 1.97
50 INT52789 Regulation of Localization of Il2 9 0.30 1.9 1.88
51 INT199591 Protein_catabolism of IL2 2 0.05 1.2 1.81
52 INT134965 Negative_regulation of Ecm1 7 0.18 7.86 1.7
53 INT97108 Phosphorylation of IL2 5 0.73 2.47 1.7
54 INT224626 Negative_regulation of Il21 3 0.10 3.51 1.67
55 INT157050 Regulation of Localization of Il2 1 0.06 0 1.67
56 INT87236 Regulation of Negative_regulation of Il2 3 0.24 0.75 1.62
57 INT180678 Negative_regulation of Protein_catabolism of Ecm1 6 0.08 2.69 1.61
58 INT88746 Positive_regulation of Transcription of IL2 7 0.51 2.14 1.6
59 INT116014 Transcription of Gata3 4 0.63 2.24 1.46
60 INT116015 Regulation of Gata3 3 0.22 1.41 1.42
61 INT159102 Regulation of Ecm1 9 0.16 1.28 1.41
62 INT116008 Binding of Gata3 2 0.34 1.37 1.41
63 INT152190 Positive_regulation of Phosphorylation of IL2 1 0.23 0.2 1.41
64 INT87029 Positive_regulation of Positive_regulation of IL2 8 0.50 8.17 1.36
65 INT116016 Positive_regulation of Positive_regulation of Gata3 2 0.21 0.5 1.28
66 INT236091 Positive_regulation of Transcription of Il2 2 0.44 2.78 1.19
67 INT97261 Negative_regulation of Regulation of IL2 2 0.26 1.04 1.17
68 INT112004 Positive_regulation of Negative_regulation of IL2 3 0.50 1.56 1.08
69 INT22830 Negative_regulation of Binding of IL2 4 0.55 4.8 1.06
70 INT180683 Positive_regulation of Protein_catabolism of Ecm1 9 0.09 2.25 1.03
71 INT353937 Localization of Il21 1 0.52 2.44 1.01
72 INT226495 Gene_expression of IL21 4 0.36 1.89 0.99
73 INT224624 Binding of Il21 2 0.09 1.61 0.99
74 INT85869 Transcription of Il2 5 0.23 2.49 0.95
75 INT248774 Positive_regulation of Localization of Ecm1 4 0.05 8.46 0.92
76 INT70817 Negative_regulation of Transcription of Il2 5 0.40 0.25 0.87
77 INT120447 Negative_regulation of Localization of Il2 9 0.56 1.74 0.86
78 INT179814 Positive_regulation of Protein_catabolism of Ecm1 5 0.06 3.38 0.85
79 INT151907 Binding of Ecm1 6 0.11 2.48 0.83
80 INT230516 Negative_regulation of Localization of Il2 5 0.15 2.64 0.79
81 INT19279 Negative_regulation of Negative_regulation of IL2 3 0.43 1.62 0.79
82 INT250847 Negative_regulation of Ecm1 1 0.03 1.72 0.78
83 INT70815 Negative_regulation of Positive_regulation of Il2 4 0.40 1.37 0.76
84 INT91274 Negative_regulation of Positive_regulation of Il2 2 0.42 1.12 0.74
85 INT116012 Regulation of Positive_regulation of Gata3 1 0.20 0.07 0.71
86 INT116006 Positive_regulation of Transcription of Gata3 1 0.21 0.07 0.7
87 INT116010 Positive_regulation of Binding of Gata3 1 0.31 0.07 0.7
88 INT292653 Positive_regulation of IL21 2 0.27 1.96 0.69
89 INT171692 Regulation of Protein_catabolism of Ecm1 4 0.12 1.5 0.65
90 INT61623 Regulation of Positive_regulation of IL2 1 0.21 0.33 0.65
91 INT202416 Negative_regulation of Gata3 2 0.32 1.17 0.64
92 INT290660 Negative_regulation of Gene_expression of Gata3 1 0.25 1.52 0.6
93 INT179337 Positive_regulation of Gene_expression of Ecm1 14 0.05 3.73 0.58
94 INT171693 Positive_regulation of Ecm1 5 0.09 2.14 0.55
95 INT132186 Negative_regulation of Gene_expression of Ecm1 2 0.06 1.73 0.54
96 INT62456 Negative_regulation of Regulation of Il2 1 0.36 0.06 0.53
97 INT102051 Negative_regulation of Negative_regulation of Il2 1 0.58 0.08 0.52
98 INT231743 Positive_regulation of Binding of Il21 1 0.12 1.13 0.51
99 INT226429 Regulation of IL21 2 0.04 0.74 0.49
100 INT285338 Negative_regulation of Transcription of Il2 1 0.08 1.97 0.48
101 INT250837 Positive_regulation of Negative_regulation of Ecm1 1 0.04 1.1 0.44
102 INT76966 Regulation of Negative_regulation of Il2 1 0.39 0.98 0.41
103 INT205725 Regulation of Regulation of Ecm1 1 0.03 0.1 0.4
104 INT212566 Regulation of Regulation of Il2 1 0.27 1.16 0.4
105 INT300543 Regulation of Il21 1 0.04 0.98 0.4
106 INT354977 Regulation of Positive_regulation of Il2 1 0.07 0.82 0.4
107 INT25388 Regulation of Binding of Il2 2 0.37 0.2 0.37
108 INT250834 Negative_regulation of Localization of Ecm1 1 0.04 0.58 0.34
109 INT353932 Positive_regulation of Gene_expression of Il21 1 0.30 0.16 0.27
110 INT298430 Positive_regulation of Protein_catabolism of IL2 1 0.03 0.85 0.26
111 INT343565 Positive_regulation of Gene_expression of Ecm1 1 0.07 0.94 0.25
112 INT254818 Positive_regulation of Positive_regulation of Ecm1 4 0.06 5.27 0.24
113 INT226447 Binding of IL21 2 0.20 0.53 0.23
114 INT293350 Regulation of Binding of IL2 2 0.22 0.87 0.23
115 INT171231 Regulation of Binding of Ecm1 2 0.06 0.2 0.19
116 INT296060 Positive_regulation of Positive_regulation of IL21 1 0.08 0.18 0.19
117 INT120448 Positive_regulation of Negative_regulation of Il2 1 0.45 0.19 0.19
118 INT11806 Positive_regulation of Positive_regulation of Il2 2 0.50 1.02 0.18
119 INT254804 Negative_regulation of Protein_catabolism of Ecm1 2 0.04 0.97 0.17
120 INT351417 Regulation of Protein_catabolism of Ecm1 1 0.00 0.98 0.17
121 INT226462 Localization of IL21 1 0.12 0.52 0.16
122 INT215001 Phosphorylation of Il2 1 0.41 0.05 0.14
123 INT120445 Negative_regulation of Negative_regulation of Il2 1 0.42 0.11 0.12
124 INT194746 Phosphorylation of Gata3 1 0.10 0.08 0.12
125 INT171221 Regulation of Gene_expression of Ecm1 1 0.06 0.08 0.1
126 INT274151 Positive_regulation of Transcription of Il2 1 0.11 0.12 0.1
127 INT218593 Regulation of Gene_expression of Ecm1 1 0.04 1.49 0.1
128 INT60073 Negative_regulation of Binding of Il2 2 0.42 1.03 0.09
129 INT315489 Regulation of Transcription of Il2 1 0.11 0 0.09
130 INT179824 Regulation of Transcription of Ecm1 1 0.08 0 0.08
131 INT179790 Transcription of Ecm1 1 0.10 0 0.08
132 INT254792 Regulation of Positive_regulation of Ecm1 2 0.06 1.86 0.07
133 INT57480 Regulation of Negative_regulation of IL2 1 0.45 0.37 0.07
134 INT244650 Positive_regulation of Binding of IL2 1 0.20 1.39 0.05
135 INT298571 Positive_regulation of Binding of Ecm1 1 0.05 0 0.04
136 INT262794 Positive_regulation of Negative_regulation of Ecm1 1 0.04 1.07 0.04
137 INT348683 Positive_regulation of Positive_regulation of Ecm1 1 0.09 0.3 0.04
138 INT235499 Regulation of Regulation of IL2 1 0.27 0 0.03
139 INT337565 Regulation of Transcription of IL2 1 0.45 0.51 0.03
140 INT243210 Negative_regulation of Gene_expression of Ecm1 3 0.05 3.1 0
141 INT237854 Negative_regulation of Localization of Ecm1 1 0.04 1.14 0
142 INT289784 Positive_regulation of Binding of Ecm1 1 0.06 0.49 0
143 INT218599 Positive_regulation of Regulation of Ecm1 1 0.04 0.14 0
144 INT183523 Transcription of Il21 1 0.52 0.53 0
145 INT183546 Transcription of IL21 1 0.06 0.54 0
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