GO:0005146

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Name leukemia inhibitory factor receptor binding
Categary Function
Go Slim No
Go Link GO:0005146
Unique Molecular Interactions 108
Total Molecular Interactions 143
Total Single Events 432
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for leukemia inhibitory factor receptor binding. They are ordered first by their pain relevance and then by number of times they were reported for leukemia inhibitory factor receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT8416 LIF Regulation of TAC1 1 0.13 0.36 1.04
2 INT8415 LIF Regulation of VIP 1 0.13 0.36 1.04
3 INT56743 LIF Positive_regulation of Cck 1 0.08 0.18 1.02
4 INT56742 LIF Positive_regulation of Chat 1 0.02 0.2 0.98
5 INT188196 LIF Regulation of MAPK1 1 0.21 2.26 0.87
6 INT98479 Lif Regulation of Gene_expression of Grin1 1 0.04 0.35 0.82
7 INT149597 Lif Regulation of Regulation of Gal 1 0.30 0.69 0.73
8 INT149596 Lif Negative_regulation of Negative_regulation of Gal 1 0.10 0.5 0.7
9 INT82267 Lif Regulation of Gene_expression of Gal 1 0.40 2.76 0.62
10 INT149595 Lif Negative_regulation of Negative_regulation of Trpv1 1 0.34 0.44 0.61
11 INT8440 Cntf Regulation of LIF 1 0.33 0.18 0.52
12 INT98480 Lif Positive_regulation of Pnoc 1 0.18 0.2 0.49
13 INT98484 Lif Regulation of Gene_expression of Gal 1 0.04 0.16 0.47
14 INT98482 Lif Positive_regulation of Gene_expression of Pnoc 1 0.16 0.17 0.46
15 INT98481 Lif Regulation of Regulation of Oprl1 1 0.04 0.16 0.45
16 INT188205 OSM Regulation of LIF 1 0.09 1.12 0.43
17 INT188207 LIF Regulation of IL6 1 0.17 1.12 0.43
18 INT91719 Binding of BDNF and LIF 1 0.09 1.65 0.38
19 INT82268 Lif Regulation of Gene_expression of Iapp 1 0.06 0.9 0.2
20 INT222426 Lif Positive_regulation of Localization of Pomc 1 0.02 0.75 0.17
21 INT32211 POMC Positive_regulation of Gene_expression of Lif 1 0.01 0.61 0.15
22 INT188197 LIF Positive_regulation of STAT3 1 0.35 0.27 0.12
23 INT294440 KLK4 Negative_regulation of LIF 1 0.00 0 0.1
24 INT355019 Lif Positive_regulation of JAK1 1 0.00 0.69 0.08
25 INT299539 Lif Positive_regulation of Phosphorylation of Stat3 1 0.08 0 0.08
26 INT355020 Lif Positive_regulation of SOAT1 1 0.02 0.7 0.08
27 INT355010 Lif Positive_regulation of Il6st 1 0.02 0.69 0.08
28 INT299548 Binding of TGFB1 and Lif 1 0.02 0 0.07
29 INT12987 LIF Regulation of Localization of Prl 1 0.09 0 0.07
30 INT299535 Binding of Egf and Lif 1 0.07 0 0.07
31 INT268652 Binding of CLDN4 and LIF 1 0.35 0.44 0.04
32 INT261388 Nsdhl Regulation of Lif 1 0.08 0.67 0.04
33 INT261377 Nsdhl Positive_regulation of Lif 1 0.08 0.6 0.03
34 INT266075 LIF Regulation of Gene_expression of PAEP 1 0.19 0.43 0.03
35 INT266070 LIF Regulation of Gene_expression of PAPPA 1 0.35 0.49 0.03
36 INT266072 LGALS1 Regulation of Gene_expression of LIF 1 0.17 0.43 0.03
37 INT266067 PAPPA Regulation of Gene_expression of LIF 1 0.35 0.49 0.03
38 INT266076 LIF Regulation of Gene_expression of LGALS1 1 0.17 0.43 0.03
39 INT66341 LIF Positive_regulation of Gene_expression of FOS 1 0.11 1.07 0
40 INT66339 LIF Positive_regulation of Phosphorylation of CLIP2 1 0.45 1.57 0
41 INT268651 NUPL2 Positive_regulation of Gene_expression of LIF 1 0.66 0.07 0
42 INT66342 LIF Positive_regulation of Phosphorylation of CLIP1 1 0.60 1.57 0
43 INT236171 Binding of LIF and Hmgcr 1 0.02 0 0
44 INT66353 LIF Regulation of Ctf2p 1 0.02 0.47 0
45 INT66340 LIF Positive_regulation of C1orf61 1 0.12 0.52 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for leukemia inhibitory factor receptor binding. They are ordered first by their pain relevance and then by number of times they were reported in leukemia inhibitory factor receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2111 Gene_expression of LIF 34 0.77 16.82 6.76
2 INT32208 Gene_expression of Lif 23 0.74 6.23 3.7
3 INT82265 Gene_expression of Lif 7 0.50 6.17 3.4
4 INT76240 Positive_regulation of Lif 6 0.69 6.04 3.13
5 INT33895 Positive_regulation of LIF 9 0.67 2.47 2.34
6 INT44027 Positive_regulation of Lif 7 0.40 2.76 1.9
7 INT253751 Localization of Lif 3 0.73 3.94 1.58
8 INT50437 Regulation of LIF 6 0.44 2.12 1.53
9 INT50436 Negative_regulation of Positive_regulation of LIF 1 0.37 0.33 1.42
10 INT34933 Positive_regulation of Gene_expression of LIF 6 0.67 3.41 1.38
11 INT149594 Positive_regulation of Gene_expression of Lif 2 0.47 0.89 1
12 INT102819 Regulation of Lif 8 0.53 2.05 0.87
13 INT98478 Negative_regulation of Lif 3 0.42 1.29 0.84
14 INT82262 Regulation of Lif 3 0.31 1.67 0.83
15 INT354449 Positive_regulation of Localization of Lif 1 0.33 1.24 0.83
16 INT68794 Negative_regulation of LIF 6 0.41 1.38 0.7
17 INT2109 Negative_regulation of Gene_expression of LIF 4 0.41 0.89 0.66
18 INT216834 Localization of Lif 2 0.34 0.23 0.46
19 INT299516 Phosphorylation of Lif 1 0.26 0.56 0.46
20 INT2110 Localization of LIF 5 0.73 1.59 0.44
21 INT32207 Regulation of Gene_expression of Lif 3 0.19 1.01 0.42
22 INT299519 Binding of Lif 2 0.21 0.67 0.29
23 INT188235 Phosphorylation of LIF 1 0.53 0.48 0.23
24 INT318610 Positive_regulation of Binding of Lif 1 0.28 0.67 0.19
25 INT188224 Regulation of Gene_expression of LIF 1 0.23 0.53 0.18
26 INT188216 Positive_regulation of Regulation of LIF 1 0.39 1.13 0.17
27 INT338147 Negative_regulation of Gene_expression of Lif 1 0.38 0.29 0.15
28 INT216451 Negative_regulation of Lif 1 0.36 0.77 0.15
29 INT333440 Protein_catabolism of Lif 1 0.23 0.2 0.08
30 INT216454 Binding of Lif 2 0.27 0.85 0.07
31 INT299524 Positive_regulation of Localization of Lif 1 0.21 0 0.06
32 INT333439 Positive_regulation of Gene_expression of Lif 1 0.18 0.18 0.04
33 INT266088 Positive_regulation of Localization of LIF 1 0.34 0.45 0.03
34 INT66346 Binding of LIF 7 0.47 0.9 0
35 INT159329 Transcription of Lif 1 0.36 0.15 0
36 INT300189 Negative_regulation of Localization of Lif 1 0.41 0.47 0
37 INT268657 Regulation of Localization of LIF 1 0.38 0.07 0
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