GO:0005158

From wiki-pain
Jump to: navigation, search
Name insulin receptor binding
Categary Function
Go Slim No
Go Link GO:0005158
Unique Molecular Interactions 1470
Total Molecular Interactions 2000
Total Single Events 22944
Pain Genes Associated 50

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for insulin receptor binding. They are ordered first by their pain relevance and then by number of times they were reported for insulin receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
2 INT30423 Penk Regulation of Localization of Ins1 4 0.26 0.77 4.42
3 INT180813 Ngf Positive_regulation of Sorbs1 1 0.04 2.09 3.79
4 INT67663 Ins1 Positive_regulation of Ntrk2 1 0.00 0.19 2.59
5 INT130284 Ins1 Negative_regulation of Gene_expression of Npy 1 0.32 0.1 2.47
6 INT151965 SORBS1 Positive_regulation of TRPV1 1 0.18 0 1.89
7 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
8 INT19496 Pomc Regulation of Localization of Ins1 1 0.55 0.33 1.82
9 INT185143 Elane Positive_regulation of Pik3r1 1 0.01 0 1.72
10 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
11 INT18520 Adra2c Positive_regulation of Localization of Ins1 3 0.41 0.63 1.66
12 INT180812 Gdnf Positive_regulation of Gene_expression of Sorbs1 1 0.02 0.83 1.61
13 INT180811 Gdnf Positive_regulation of Regulation of Sorbs1 1 0.01 0.83 1.61
14 INT26985 Cpe Negative_regulation of Localization of Ins1 1 0.02 0 1.57
15 INT41100 Mdk Positive_regulation of Localization of INS 1 0.01 0 1.55
16 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
17 INT112033 Gabrb3 Positive_regulation of Plcg1 1 0.05 0.18 1.49
18 INT112034 Gabrb3 Positive_regulation of Pik3r1 1 0.08 0.18 1.48
19 INT180804 Bdnf Positive_regulation of Gene_expression of Sorbs1 1 0.01 0 1.44
20 INT180809 Ngf Positive_regulation of Positive_regulation of Sorbs1 1 0.03 0.84 1.4
21 INT180808 Ngf Positive_regulation of Gene_expression of Sorbs1 1 0.03 0.84 1.4
22 INT96262 Positive_regulation of Pik3cd Positive_regulation of Plcg1 1 0.03 0 1.39
23 INT180802 Gdnf Positive_regulation of Sorbs1 1 0.02 0.98 1.34
24 INT180807 Calca Regulation of Sorbs1 1 0.02 0 1.32
25 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31
26 INT131184 PTGER2 Positive_regulation of Gene_expression of IGF1 1 0.63 2.47 1.29
27 INT19819 Penk Regulation of Gene_expression of Ins1 1 0.05 0 1.27
28 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
29 INT18324 Sst Negative_regulation of Localization of Ins1 2 0.46 1.09 1.24
30 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
31 INT131462 NGF Regulation of Localization of INS 1 0.40 0.97 1.2
32 INT68157 Alox5 Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.13
33 INT68154 Mthfs Positive_regulation of Pdpk1 1 0.01 0.63 1.12
34 INT121362 Trpv1 Regulation of Localization of Ins1 1 0.51 0.17 1.12
35 INT68158 Pla2g1b Positive_regulation of Pdpk1 1 0.05 0.63 1.12
36 INT68159 Pla2g1b Positive_regulation of Positive_regulation of Pdpk1 1 0.05 0.64 1.12
37 INT68163 Mthfs Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.12
38 INT68165 Alox5 Positive_regulation of Pdpk1 1 0.01 0.63 1.12
39 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12
40 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
41 INT180806 Ngf Positive_regulation of Regulation of Sorbs1 1 0.03 0.28 1.04
42 INT19494 Pomc Positive_regulation of Localization of Ins1 2 0.62 0.38 1.02
43 INT106345 Igf1 Regulation of Localization of Acot1 1 0.06 0 1.02
44 INT121743 Negative_regulation of Src Negative_regulation of Ephb1 1 0.27 0 1.02
45 INT12138 Ins1 Negative_regulation of Chat 1 0.27 0.71 1.01
46 INT12141 Igf1 Negative_regulation of Chat 1 0.32 0.63 1
47 INT317518 Src Regulation of Negative_regulation of Oprm1 1 0.16 0.07 1
48 INT54853 Negative_regulation of Adra1a Positive_regulation of Positive_regulation of Ins1 1 0.18 0.23 1
49 INT317564 Pik3r1 Regulation of Negative_regulation of Oprm1 1 0.13 0.07 1
50 INT143915 Src Regulation of Rbm39 1 0.03 0.18 0.99
51 INT54852 Negative_regulation of Adra1a Positive_regulation of Ins1 1 0.18 0.23 0.99
52 INT140653 IGF1 Negative_regulation of Protein_catabolism of PARP1 1 0.32 0.63 0.98
53 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
54 INT40424 CCK Regulation of Localization of INS 1 0.02 0 0.97
55 INT37308 Ins1 Regulation of Localization of Gast 1 0.20 0 0.97
56 INT75283 SST Negative_regulation of Localization of INS 2 0.47 1.45 0.96
57 INT121744 Src Positive_regulation of Positive_regulation of Ephb1 1 0.35 0 0.96
58 INT180803 Sorbs1 Regulation of Gdnf 1 0.01 0.28 0.95
59 INT72386 Egf Positive_regulation of Phosphorylation of Shc1 1 0.09 0.18 0.93
60 INT107335 Pdpk1 Positive_regulation of Regulation of Sigmar1 1 0.02 0 0.93
61 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92
62 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
63 INT115656 Glp1r Positive_regulation of Localization of Ins1 2 0.42 5.23 0.91
64 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
65 INT54854 Sorbs1 Regulation of Ins1 1 0.34 0.23 0.9
66 INT12766 Ins1 Positive_regulation of Prkcg 3 0.53 0.07 0.89
67 INT26991 Pomc Negative_regulation of Localization of Ins1 1 0.38 0 0.89
68 INT109103 MMP2 Positive_regulation of INS 1 0.33 1.07 0.89
69 INT18325 Grem2 Positive_regulation of Ins1 1 0.02 0.9 0.88
70 INT26987 Pomc Regulation of Ins1 1 0.40 0 0.87
71 INT26984 Cpe Regulation of Ins1 1 0.02 0 0.87
72 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 0.01 0.5 0.87
73 INT114546 Ins1 Positive_regulation of Positive_regulation of Trpv1 1 0.39 0.19 0.86
74 INT30422 Penk Regulation of Ins1 1 0.06 0 0.85
75 INT115655 Glp1r Positive_regulation of Ins1 1 0.42 0 0.84
76 INT12142 Ins1 Regulation of Chat 1 0.24 0.69 0.84
77 INT69084 Binding of Adrb1 and Positive_regulation of Positive_regulation of Pdpk1 1 0.02 0.08 0.83
78 INT309001 Ins1 Positive_regulation of Mmp9 1 0.20 1.96 0.83
79 INT317513 Oprm1 Regulation of Positive_regulation of Src 1 0.09 0.4 0.82
80 INT317570 Oprm1 Regulation of Src 1 0.04 0.4 0.82
81 INT120149 Positive_regulation of Pomc Positive_regulation of Localization of Ins1 1 0.03 0.09 0.82
82 INT41108 Adarb1 Positive_regulation of Localization of Ins1 1 0.03 0 0.81
83 INT262564 Ngf Positive_regulation of Pik3r1 1 0.08 0.36 0.8
84 INT131463 NTRK1 Regulation of Localization of INS 1 0.41 0.63 0.8
85 INT181616 INS Positive_regulation of IRS1 1 0.01 1 0.79
86 INT181615 SRC Positive_regulation of IRS1 1 0.01 0.98 0.77
87 INT316544 BCL2L11 Regulation of INS 1 0.00 1.36 0.77
88 INT114547 Ins1 Positive_regulation of Trpv1 1 0.36 0.19 0.77
89 INT107602 Binding of OPLL and Enpp1 1 0.15 1.12 0.76
90 INT164996 Ins1 Regulation of Gria2 1 0.05 0.05 0.76
91 INT26983 Cpe Regulation of Localization of Ins1 1 0.02 0 0.75
92 INT19818 Penk Positive_regulation of Gene_expression of Ins1 1 0.32 0 0.74
93 INT41165 Gtf3a Regulation of INS 1 0.00 0.15 0.74
94 INT45822 Pah Positive_regulation of Localization of Ins1 1 0.01 0.3 0.73
95 INT101442 Penk Positive_regulation of Localization of Ins1 1 0.29 0.9 0.73
96 INT41164 Binding of INS and SST 1 0.07 0.14 0.73
97 INT31643 POMC Regulation of INS 1 0.59 0.62 0.73
98 INT317547 Src Positive_regulation of Positive_regulation of Grin1 1 0.17 0 0.72
99 INT148453 Gene_expression of Inhbe Positive_regulation of Src 1 0.06 0.68 0.72
100 INT64117 Binding of Edn1 and Ins1 1 0.06 0.85 0.71
101 INT317573 Binding of Oprm1 and Pik3r1 1 0.12 0.33 0.71
102 INT81735 Binding of Ins1 and Pomc 1 0.20 2.24 0.71
103 INT31417 Cocia8 Positive_regulation of Ins1 1 0.01 0 0.7
104 INT31415 Regulation of Cocia8 Positive_regulation of Ins1 1 0.00 0 0.7
105 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69
106 INT34772 GH1 Regulation of IGF1 2 0.32 0.95 0.69
107 INT27690 Ins1 Negative_regulation of GYPA 1 0.00 0.73 0.69
108 INT94241 Binding of Cp and Slc2a2 1 0.13 0.81 0.67
109 INT180805 Bdnf Regulation of Sorbs1 1 0.01 0.14 0.67
110 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66
111 INT28975 Ins1 Positive_regulation of Positive_regulation of Dbh 1 0.21 0 0.66
112 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
113 INT317560 Binding of Pdpk1 and Pik3r1 1 0.13 0 0.65
114 INT45369 IGF1 Regulation of GH1 1 0.04 1.12 0.65
115 INT309664 Binding of Pik3r1 and Cia1 1 0.02 1.32 0.64
116 INT116752 Ngf Regulation of Pik3r1 1 0.56 0.29 0.63
117 INT253137 Ptpn1 Negative_regulation of Ins1 1 0.19 4.11 0.63
118 INT139901 Ins1 Positive_regulation of Akt1 9 0.31 4.58 0.6
119 INT242883 INS Negative_regulation of Gene_expression of TLR2 1 0.17 2.35 0.6
120 INT29847 INS Regulation of Localization of AVP 1 0.23 0.24 0.59
121 INT317638 Ins1 Positive_regulation of Gene_expression of Drd1a 1 0.14 0.86 0.59
122 INT317634 Ins1 Positive_regulation of Drd1a 1 0.14 0.86 0.59
123 INT321300 Ins1 Negative_regulation of Pck1 1 0.09 0.52 0.59
124 INT321285 Ins1 Negative_regulation of G6pc 1 0.07 0.52 0.59
125 INT291262 Positive_regulation of INS Positive_regulation of Mapk1 1 0.03 1.78 0.58
126 INT94240 Binding of Cp and Ins1 1 0.02 0.7 0.58
127 INT261828 Igf1 Regulation of Localization of Trpv2 1 0.02 1.04 0.58
128 INT100225 Binding of Egf and Src 1 0.01 0.67 0.58
129 INT291258 INS Positive_regulation of Mapk1 1 0.04 1.77 0.58
130 INT103165 NGF Positive_regulation of Localization of INS 1 0.05 0 0.58
131 INT156668 Gh Positive_regulation of Igf1 5 0.22 2.07 0.57
132 INT317639 Igf1 Regulation of Creb1 1 0.23 0.16 0.57
133 INT192291 OR5A1 Positive_regulation of Gene_expression of IGF1 1 0.02 0.93 0.57
134 INT156667 Gh Positive_regulation of Gene_expression of Igf1 6 0.28 0.88 0.56
135 INT150291 Grk1 Positive_regulation of Gene_expression of Igf1 1 0.16 0.98 0.55
136 INT106347 Igf1 Regulation of Chat 1 0.44 0 0.55
137 INT72387 Trim13 Regulation of Phosphorylation of Shc1 1 0.32 0.09 0.54
138 INT29252 Regulation of INS Positive_regulation of GH1 1 0.26 0.08 0.54
139 INT240808 Arc Regulation of Ins1 1 0.09 1.41 0.54
140 INT80833 Oxt Regulation of Ins1 1 0.04 0 0.53
141 INT80835 Oxt Positive_regulation of Regulation of Ins1 1 0.04 0 0.53
142 INT5631 Ubqln1 Positive_regulation of Pdpk1 1 0.05 0 0.53
143 INT29253 INS Positive_regulation of GH1 1 0.44 0.08 0.53
144 INT109307 Pik3r1 Positive_regulation of Phosphorylation of Akt1 1 0.29 0.4 0.53
145 INT3218 Adrb2 Positive_regulation of Localization of Ins1 1 0.10 0 0.52
146 INT311767 INS Negative_regulation of Gene_expression of SLC1A3 1 0.52 0 0.52
147 INT317565 Oprm1 Positive_regulation of Pik3r1 1 0.14 0.05 0.52
148 INT142882 IGF1 Positive_regulation of Gene_expression of TRPV1 1 0.06 0.57 0.52
149 INT30028 Ins1 Regulation of Odc1 2 0.11 0 0.51
150 INT160203 Prkcc Positive_regulation of Src 1 0.02 0 0.51
151 INT98737 Src Negative_regulation of Tk1 1 0.22 0.15 0.5
152 INT308656 Pik3r1 Positive_regulation of Nos3 1 0.02 1.8 0.5
153 INT98735 Src Negative_regulation of Egf 1 0.26 0.15 0.5
154 INT31712 Ptger2 Positive_regulation of Localization of Ins1 1 0.13 0.06 0.49
155 INT259180 Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
156 INT259181 Phosphorylation of Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
157 INT108568 Calca Positive_regulation of Igf1 1 0.51 0.08 0.48
158 INT101001 GHRH Regulation of Localization of INS 1 0.28 0 0.47
159 INT280614 Il6 Regulation of Transcription of Irs1 1 0.26 0.4 0.46
160 INT95469 P2ry6 Positive_regulation of Positive_regulation of Pdpk1 1 0.15 0 0.46
161 INT340291 Ea1 Regulation of Gene_expression of Ins1 1 0.03 0.62 0.46
162 INT341211 Gopc Regulation of Shc1 1 0.02 0.68 0.45
163 INT168129 Binding of Yy1 and Positive_regulation of Transcription of Tln2 1 0.02 0 0.44
164 INT225775 Enpp1 Positive_regulation of Ppi-rs 1 0.06 2.49 0.44
165 INT264295 Binding of DMD and IGF1 1 0.07 1.38 0.44
166 INT348784 Ins1 Positive_regulation of Irs1 1 0.09 3.47 0.44
167 INT340292 Ea1 Positive_regulation of Ins1 1 0.04 0.6 0.43
168 INT323484 Ghsr Positive_regulation of Localization of Ins1 1 0.27 0.87 0.43
169 INT168132 Binding of Yy1 and Tln2 1 0.01 0 0.43
170 INT15024 Prkcg Regulation of Pdpk1 1 0.09 0 0.43
171 INT151184 Pdpk1 Positive_regulation of Trpv1 1 0.08 0 0.42
172 INT51167 Defb35 Regulation of Localization of Ins1 1 0.02 0.08 0.42
173 INT12139 Ins1 Regulation of Gad1 1 0.15 0.33 0.42
174 INT151183 Pdpk1 Positive_regulation of Phosphorylation of Trpv1 1 0.08 0 0.42
175 INT348785 Ins1 Positive_regulation of Phosphorylation of Akt1 1 0.17 3.5 0.42
176 INT221085 GHRH Positive_regulation of Gene_expression of IGF1 2 0.56 1.47 0.41
177 INT303655 Positive_regulation of Binding of IGF1 and SSTR1 1 0.16 2.19 0.41
178 INT261790 SHC1 Positive_regulation of Slc12a5 1 0.02 0.06 0.41
179 INT240618 Binding of INS and ADIPOQ 3 0.17 2.54 0.4
180 INT276216 Binding of Akt1 and Ins1 2 0.03 2.61 0.4
181 INT64640 Ins1 Regulation of LH 1 0.13 0.38 0.4
182 INT285725 Binding of IGF1R and INS 1 0.27 0.07 0.4
183 INT323491 Olfr781 Positive_regulation of Localization of Ins1 1 0.01 0.87 0.4
184 INT29052 Binding of INS and INSRR 1 0.02 0.23 0.4
185 INT153422 Ins1 Regulation of Transcription of Qrfp 1 0.08 0.23 0.4
186 INT303650 Binding of IGF1 and SSTR1 1 0.12 2.17 0.4
187 INT29053 Regulation of Binding of INS and INSRR 1 0.01 0.24 0.4
188 INT78621 PRL Positive_regulation of Localization of INS 2 0.06 0.5 0.39
189 INT291256 INS Negative_regulation of Positive_regulation of Mdk 1 0.01 1.65 0.39
190 INT99304 Igf1 Positive_regulation of Gh1 1 0.44 0.39 0.39
191 INT236111 Binding of Pdpk1 and Ppara 1 0.26 1.21 0.39
192 INT166157 Ccr9 Positive_regulation of Pik3r1 1 0.55 2.14 0.39
193 INT64642 Ins1 Positive_regulation of Localization of Gnrh1 1 0.06 0.44 0.39
194 INT12767 Ins1 Positive_regulation of Phosphorylation of Prkcg 1 0.36 0 0.38
195 INT40395 Ins1 Positive_regulation of Localization of Avp 1 0.16 0.09 0.38
196 INT64641 Ins1 Positive_regulation of Gnrh1 1 0.06 0.44 0.38
197 INT182492 IL1B Regulation of Gene_expression of IGF1 1 0.01 0.83 0.38
198 INT146611 Ins1 Positive_regulation of Phosphorylation of Akt1 9 0.23 4.34 0.37
199 INT78444 Binding of GH1 and IGF1 4 0.16 2.82 0.37
200 INT113040 IHH Regulation of Gene_expression of INS 1 0.12 0.37 0.37

Single Events

The table below shows the top 100 pain related interactions that have been reported for insulin receptor binding. They are ordered first by their pain relevance and then by number of times they were reported in insulin receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1114 Localization of Ins1 748 0.80 192.95 165.48
2 INT812 Localization of INS 1026 0.81 515.6 145.31
3 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01
4 INT1472 Positive_regulation of Ins1 349 0.69 146.2 86.36
5 INT3214 Localization of Ins1 527 0.80 196.9 79.26
6 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76
7 INT1988 Positive_regulation of Localization of Ins1 254 0.69 59.25 68.37
8 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07
9 INT1200 Negative_regulation of Ins1 274 0.58 155.17 56.14
10 INT251 Regulation of INS 398 0.62 232.47 55.04
11 INT2276 Regulation of Ins1 234 0.61 103.78 54.05
12 INT3213 Gene_expression of Ins1 511 0.76 357.59 53.32
13 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43
14 INT1232 Positive_regulation of Pdpk1 78 0.42 24.33 50.17
15 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98
16 INT2275 Negative_regulation of Localization of Ins1 183 0.59 51.02 44.94
17 INT1474 Regulation of Localization of Ins1 132 0.61 25.96 43.07
18 INT18992 Negative_regulation of Pdpk1 53 0.42 19.02 40.95
19 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52
20 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61
21 INT3216 Positive_regulation of Localization of Ins1 170 0.69 56.78 35.63
22 INT8747 Positive_regulation of Ins1 221 0.69 154.28 35.15
23 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79
24 INT14559 Gene_expression of Igf1 254 0.78 112 34.17
25 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51
26 INT3217 Regulation of Ins1 154 0.62 87.11 27.29
27 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36
28 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04
29 INT18323 Negative_regulation of Localization of Ins1 122 0.58 45.74 23.04
30 INT18322 Negative_regulation of Ins1 132 0.58 88.49 22.59
31 INT112029 Positive_regulation of Pik3r1 90 0.67 38.76 20.95
32 INT48769 Regulation of Pdpk1 20 0.35 9.78 20.36
33 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9
34 INT3656 Positive_regulation of Gene_expression of Ins1 74 0.54 44.94 17.36
35 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47
36 INT8742 Regulation of Localization of Ins1 65 0.61 14.98 16.43
37 INT6110 Negative_regulation of Gene_expression of Ins1 83 0.56 60.59 16.07
38 INT112027 Gene_expression of Pik3r1 58 0.75 30.9 15.95
39 INT65263 Positive_regulation of Gene_expression of Igf1 61 0.69 25.69 14.49
40 INT26733 Gene_expression of Pdpk1 17 0.48 5.74 13.91
41 INT14572 Binding of INS 205 0.48 175.43 13.38
42 INT89842 Phosphorylation of Src 34 0.69 9.57 13.08
43 INT17539 Positive_regulation of Igf1 68 0.69 28.47 13.02
44 INT2578 Binding of Ins1 74 0.48 33.57 12.92
45 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83
46 INT114420 Negative_regulation of Pik3r1 67 0.54 34.86 12.82
47 INT74838 Positive_regulation of Sorbs1 18 0.34 6.93 12.63
48 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32
49 INT8533 Regulation of Sorbs1 9 0.27 3.01 11.98
50 INT5630 Localization of Pdpk1 10 0.45 5.21 11.36
51 INT96259 Positive_regulation of Plcg1 11 0.49 3.01 11.15
52 INT8021 Gene_expression of Enpp1 43 0.78 31.46 10.8
53 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75
54 INT11729 Regulation of IGF1 71 0.61 44.58 9.71
55 INT8535 Localization of Sorbs1 9 0.80 2.71 9.07
56 INT89845 Positive_regulation of Src 19 0.44 7.5 9.01
57 INT34777 Localization of IGF1 82 0.80 42.68 8.62
58 INT12762 Negative_regulation of Positive_regulation of Ins1 24 0.59 8.51 8.28
59 INT18583 Positive_regulation of Gene_expression of Ins1 67 0.50 49.72 8.26
60 INT72539 Gene_expression of Sorbs1 10 0.78 4.98 8.14
61 INT3803 Negative_regulation of Igf1 45 0.58 15.95 7.98
62 INT104013 Negative_regulation of Gene_expression of Pdpk1 4 0.31 2.36 7.89
63 INT110004 Gene_expression of Plcg1 7 0.41 2.61 7.87
64 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53
65 INT71824 Phosphorylation of Pdpk1 14 0.38 4.9 6.86
66 INT142344 Transcription of Igf1 22 0.69 7.55 6.77
67 INT2217 Positive_regulation of Positive_regulation of Ins1 21 0.69 7.66 6.32
68 INT14560 Regulation of Igf1 41 0.59 19.59 6.3
69 INT9494 Positive_regulation of Gene_expression of Igf1 34 0.67 17.77 6.26
70 INT9495 Negative_regulation of Gene_expression of Igf1 31 0.59 11.87 6.1
71 INT9321 Transcription of Igf1 25 0.69 10.2 6.08
72 INT224530 Positive_regulation of Enpp1 12 0.70 7.03 5.82
73 INT8916 Regulation of Igf1 45 0.60 13.06 5.81
74 INT55077 Positive_regulation of Positive_regulation of Pdpk1 6 0.26 1.77 5.78
75 INT151032 Localization of Igf1 49 0.76 26.32 5.71
76 INT17425 Regulation of Gene_expression of Ins1 23 0.45 18.99 5.61
77 INT68465 Positive_regulation of Gene_expression of Pdpk1 7 0.19 2.35 5.49
78 INT9325 Gene_expression of Igf1r 14 0.77 8.74 5.48
79 INT74250 Negative_regulation of Gene_expression of Ins1 47 0.40 39.27 5.37
80 INT100222 Binding of Src 9 0.26 5.41 5.37
81 INT2579 Protein_catabolism of Ins1 43 0.99 9.91 5.14
82 INT116744 Binding of Pik3r1 22 0.36 12.77 5.01
83 INT89844 Positive_regulation of Phosphorylation of Src 10 0.43 4.71 4.95
84 INT100220 Negative_regulation of Src 13 0.41 6.37 4.93
85 INT3215 Regulation of Gene_expression of Ins1 32 0.52 19.83 4.85
86 INT116748 Positive_regulation of Gene_expression of Pik3r1 18 0.49 9.83 4.63
87 INT98453 Positive_regulation of Src 19 0.47 7.84 4.62
88 INT72538 Negative_regulation of Sorbs1 7 0.59 4.49 4.61
89 INT230810 Phosphorylation of Ins1 59 0.69 41.15 4.51
90 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45
91 INT116747 Regulation of Pik3r1 18 0.60 9.33 4.34
92 INT49360 Localization of Igf1 22 0.76 6.96 4.26
93 INT230796 Phosphorylation of Irs1 70 0.81 31.73 4.13
94 INT1231 Negative_regulation of Positive_regulation of Pdpk1 6 0.35 1.88 4.13
95 INT72385 Phosphorylation of Shc1 11 0.52 1.62 4.1
96 INT89394 Phosphorylation of INS 37 0.82 35.84 3.9
97 INT142174 Regulation of Gene_expression of Igf1 28 0.60 11.86 3.77
98 INT25709 Negative_regulation of Igf2 11 0.56 9.38 3.76
99 INT8536 Binding of Sorbs1 2 0.14 1.24 3.64
100 INT122327 Regulation of Src 6 0.59 0.59 3.6
101 INT207570 Phosphorylation of IRS1 45 0.71 33.27 3.42
102 INT137350 Phosphorylation of Src 13 0.45 4.14 3.32
103 INT106341 Phosphorylation of Irs1 18 0.72 14.7 3.3
104 INT68445 Gene_expression of ENPP1 10 0.70 10.8 3.3
105 INT105537 Regulation of Gene_expression of Igf1 15 0.58 6.97 3.23
106 INT165911 Localization of Pik3r1 15 0.51 7.94 3.2
107 INT131187 Regulation of Gene_expression of IGF1 18 0.62 11.18 3.05
108 INT21606 Positive_regulation of Regulation of Ins1 8 0.41 3.9 2.97
109 INT207851 Regulation of Enpp1 5 0.45 4.42 2.96
110 INT16130 Binding of IGF1 67 0.48 27.43 2.95
111 INT38987 Protein_catabolism of INS 21 0.99 11.92 2.91
112 INT32623 Negative_regulation of Regulation of INS 16 0.43 10.96 2.9
113 INT72384 Positive_regulation of Phosphorylation of Shc1 1 0.32 0.48 2.9
114 INT140378 Negative_regulation of Irs2 4 0.57 1.77 2.86
115 INT106340 Positive_regulation of Phosphorylation of Irs1 8 0.53 7.03 2.85
116 INT31412 Negative_regulation of Positive_regulation of Ins1 10 0.40 7.14 2.82
117 INT24279 Gene_expression of INSL3 11 0.75 12.46 2.8
118 INT9335 Gene_expression of Igf2 18 0.72 12.76 2.78
119 INT47846 Negative_regulation of Localization of Pdpk1 2 0.33 1.12 2.75
120 INT4329 Regulation of Regulation of Ins1 10 0.61 3.17 2.72
121 INT96763 Positive_regulation of Localization of Pdpk1 1 0.39 2.08 2.65
122 INT10267 Regulation of Positive_regulation of Ins1 11 0.24 2.74 2.63
123 INT176531 Gene_expression of SHC1 3 0.67 9.5 2.62
124 INT225253 Positive_regulation of Phosphorylation of Src 4 0.38 2.36 2.59
125 INT122060 Positive_regulation of Positive_regulation of Sorbs1 2 0.34 0.06 2.57
126 INT136681 Gene_expression of Shc1 13 0.77 9.67 2.52
127 INT139735 Positive_regulation of Transcription of Igf1 4 0.53 1.93 2.49
128 INT66544 Binding of Igf1 23 0.46 8.33 2.44
129 INT9327 Localization of Igf2 8 0.80 5.07 2.36
130 INT139896 Phosphorylation of Ins1 29 0.77 24.03 2.35
131 INT109305 Phosphorylation of Pik3r1 13 0.53 5.69 2.32
132 INT25208 Gene_expression of IGF2 43 0.74 30.64 2.31
133 INT29402 Gene_expression of Src 16 0.74 4.57 2.29
134 INT3315 Negative_regulation of Positive_regulation of INS 31 0.57 14.73 2.27
135 INT107597 Binding of Enpp1 5 0.37 3.35 2.23
136 INT57132 Positive_regulation of Igf2 9 0.50 5.15 2.22
137 INT147417 Positive_regulation of Gene_expression of Igf1r 3 0.46 1.69 2.2
138 INT26177 Regulation of Regulation of INS 19 0.44 11.32 2.18
139 INT8537 Negative_regulation of Regulation of Sorbs1 1 0.18 0 2.17
140 INT28739 Binding of Ins1 35 0.37 22.43 2.14
141 INT114421 Positive_regulation of Positive_regulation of Pik3r1 9 0.49 4.07 2.13
142 INT2581 Regulation of Binding of Ins1 7 0.61 2.05 2.08
143 INT168115 Transcription of Tln2 1 0.02 0 2.06
144 INT237322 Gene_expression of Irs1 52 0.77 21.07 2
145 INT316778 Positive_regulation of Gene_expression of ENPP1 1 0.62 7.2 1.97
146 INT110003 Phosphorylation of Plcg1 2 0.37 0.91 1.96
147 INT156666 Positive_regulation of Localization of Igf1 11 0.62 6.94 1.95
148 INT142341 Positive_regulation of Transcription of Igf1 8 0.49 2.44 1.95
149 INT122534 Binding of Shc1 6 0.48 3.59 1.94
150 INT132971 Negative_regulation of Localization of IGF1 5 0.42 3.98 1.94
151 INT94239 Negative_regulation of Slc2a2 4 0.43 2.34 1.94
152 INT9336 Negative_regulation of Gene_expression of Igf1r 4 0.42 3.53 1.92
153 INT249530 Positive_regulation of Positive_regulation of Src 3 0.28 1.32 1.9
154 INT257755 Positive_regulation of SHC1 1 0.60 4.97 1.87
155 INT3866 Positive_regulation of Positive_regulation of INS 30 0.59 21.58 1.86
156 INT26735 Regulation of Gene_expression of Pdpk1 2 0.24 0.56 1.84
157 INT224529 Positive_regulation of Gene_expression of Enpp1 15 0.70 12.75 1.81
158 INT104014 Negative_regulation of Phosphorylation of Pdpk1 2 0.23 0.59 1.72
159 INT207100 Gene_expression of Ptpn1 13 0.73 8.13 1.68
160 INT8741 Regulation of Positive_regulation of Ins1 5 0.41 1.36 1.67
161 INT146943 Gene_expression of Src 13 0.49 6.65 1.65
162 INT66709 Transcription of IGF1 13 0.71 5.65 1.64
163 INT230799 Positive_regulation of Phosphorylation of Irs1 28 0.69 11.17 1.63
164 INT136680 Negative_regulation of Gene_expression of Shc1 4 0.43 3.36 1.57
165 INT240031 Positive_regulation of Phosphorylation of IRS1 15 0.46 13.17 1.53
166 INT332460 Regulation of Binding of Enpp1 1 0.05 0.78 1.5
167 INT49361 Regulation of Positive_regulation of Igf1 2 0.45 2.15 1.49
168 INT98455 Regulation of Src 4 0.20 1.76 1.48
169 INT20509 Positive_regulation of Negative_regulation of Ins1 7 0.48 2.8 1.46
170 INT21652 Negative_regulation of Negative_regulation of Ins1 7 0.39 4.16 1.46
171 INT136678 Positive_regulation of Gene_expression of Shc1 4 0.50 2.93 1.42
172 INT135959 Negative_regulation of Gene_expression of Igf1 37 0.56 21.16 1.41
173 INT81733 Transcription of Ins1 9 0.50 6.27 1.41
174 INT67464 Positive_regulation of Negative_regulation of Pdpk1 1 0.19 0.15 1.41
175 INT49128 Gene_expression of IGF1R 35 0.63 23.48 1.39
176 INT109301 Positive_regulation of Phosphorylation of Pik3r1 5 0.42 1.45 1.38
177 INT118927 Positive_regulation of Phosphorylation of Pdpk1 2 0.04 0.76 1.38
178 INT90491 Binding of Igf1 25 0.44 9.75 1.36
179 INT240842 Positive_regulation of Gene_expression of Irs1 31 0.69 12 1.31
180 INT120970 Negative_regulation of Irs1 12 0.37 8.65 1.28
181 INT10266 Negative_regulation of Regulation of Ins1 9 0.43 3.68 1.28
182 INT180763 Positive_regulation of Binding of Sorbs1 1 0.02 1.25 1.26
183 INT180762 Negative_regulation of Binding of Sorbs1 1 0.02 1.24 1.26
184 INT221206 Phosphorylation of Pdpk1 3 0.53 0.13 1.25
185 INT107599 Negative_regulation of Enpp1 8 0.51 6.02 1.24
186 INT109104 Positive_regulation of Protein_catabolism of INS 4 0.50 4.44 1.24
187 INT9323 Transcription of Igf1r 2 0.63 1.08 1.23
188 INT175520 Gene_expression of Igf2 43 0.78 48.93 1.21
189 INT110001 Binding of Plcg1 2 0.36 0.44 1.21
190 INT9324 Negative_regulation of Gene_expression of Igf2 6 0.50 5.12 1.2
191 INT104011 Transcription of Pdpk1 1 0.28 0 1.2
192 INT104012 Regulation of Transcription of Pdpk1 1 0.14 0 1.2
193 INT26734 Binding of Pdpk1 4 0.29 1.01 1.19
194 INT25710 Regulation of Igf2 6 0.62 3.1 1.17
195 INT142616 Negative_regulation of Positive_regulation of Igf1 5 0.43 1.56 1.16
196 INT118258 Positive_regulation of ENPP1 3 0.62 4.26 1.16
197 INT3486 Positive_regulation of Regulation of INS 9 0.47 5.65 1.15
198 INT18586 Negative_regulation of Regulation of Ins1 8 0.43 2.89 1.15
199 INT183046 Transcription of INS 25 0.70 11.14 1.13
200 INT54851 Positive_regulation of Positive_regulation of Ins1 6 0.46 1.22 1.12
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox