GO:0005161

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Name platelet-derived growth factor receptor binding
Categary Function
Go Slim No
Go Link GO:0005161
Unique Molecular Interactions 888
Total Molecular Interactions 1303
Total Single Events 9626
Pain Genes Associated 27

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for platelet-derived growth factor receptor binding. They are ordered first by their pain relevance and then by number of times they were reported for platelet-derived growth factor receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
2 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
3 INT185143 Elane Positive_regulation of Pik3r1 1 0.01 0 1.72
4 INT194863 Binding of IL1R1 and IL1RN 5 0.09 2.23 1.64
5 INT229094 Binding of IL1RN and Il1r1 1 0.01 1.9 1.5
6 INT112034 Gabrb3 Positive_regulation of Pik3r1 1 0.08 0.18 1.48
7 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
8 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
9 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
10 INT271602 Binding of Pdgfa and Pdgfrl 1 0.02 0.86 1.25
11 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
12 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2
13 INT204558 Tens1 Negative_regulation of Pdgfc 1 0.01 0.25 1.2
14 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
15 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
16 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
17 INT317564 Pik3r1 Regulation of Negative_regulation of Oprm1 1 0.13 0.07 1
18 INT281375 Il1r1 Negative_regulation of Gene_expression of Fos 1 0.47 0.61 0.97
19 INT161231 Positive_regulation of Htr1a Positive_regulation of Gene_expression of VEGFA 1 0.67 0.16 0.95
20 INT137922 VEGFA Positive_regulation of Oprm1 1 0.06 0 0.94
21 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
22 INT137921 VEGFA Positive_regulation of Ephb2 1 0.03 0 0.93
23 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92
24 INT149386 Binding of Lyn and TRPV4 1 0.40 1.14 0.91
25 INT271601 Pdgfa Positive_regulation of Pdgfrl 1 0.03 0.83 0.91
26 INT116108 VEGFA Positive_regulation of SEC23IP 1 0.10 0.3 0.83
27 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
28 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
29 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
30 INT262564 Ngf Positive_regulation of Pik3r1 1 0.08 0.36 0.8
31 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74
32 INT259556 PLEK Negative_regulation of Gene_expression of VEGFA 1 0.46 2.15 0.73
33 INT259557 PLEK Negative_regulation of Positive_regulation of VEGFA 1 0.46 2.15 0.73
34 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
35 INT317573 Binding of Oprm1 and Pik3r1 1 0.12 0.33 0.71
36 INT120018 VEGFA Positive_regulation of CCL3 1 0.01 1 0.7
37 INT120020 VEGFA Positive_regulation of CCL2 1 0.00 1 0.7
38 INT120036 VEGFA Positive_regulation of Prap1 1 0.00 1 0.7
39 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
40 INT229085 IL1RN Negative_regulation of Positive_regulation of IL1R1 1 0.12 1.72 0.68
41 INT167355 VEGFA Regulation of RYBP 1 0.01 0.53 0.68
42 INT74728 Binding of Slc6a4 and Ptprj 1 0.01 0.48 0.68
43 INT168295 PROC Regulation of Gene_expression of VEGFA 2 0.00 1.6 0.67
44 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67
45 INT74729 Binding of Mpz and Ptprj 1 0.06 0.15 0.66
46 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
47 INT317560 Binding of Pdpk1 and Pik3r1 1 0.13 0 0.65
48 INT309664 Binding of Pik3r1 and Cia1 1 0.02 1.32 0.64
49 INT116752 Ngf Regulation of Pik3r1 1 0.56 0.29 0.63
50 INT174860 VEGFA Positive_regulation of Localization of CCL2 1 0.21 1.68 0.63
51 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
52 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61
53 INT224731 Binding of VEGFA and Cia1 1 0.01 0.91 0.61
54 INT224733 Negative_regulation of Binding of VEGFA and Cia1 1 0.01 0.91 0.61
55 INT98629 VEGFA Positive_regulation of Gene_expression of EGR1 1 0.52 0.42 0.61
56 INT98628 VEGFA Positive_regulation of Transcription of EGR1 1 0.52 0.42 0.61
57 INT145661 Ptger2 Positive_regulation of Gene_expression of VEGFA 4 0.27 2.73 0.6
58 INT299286 VEGFA Positive_regulation of PI3 1 0.16 0.46 0.6
59 INT342624 VEGFA Negative_regulation of Mmp2 1 0.09 1.54 0.58
60 INT327339 Gtf3a Positive_regulation of VEGFA 1 0.00 2.34 0.58
61 INT304326 Ptger1 Positive_regulation of Gene_expression of VEGFA 1 0.19 1.37 0.57
62 INT85487 IL1RN Negative_regulation of IL1R1 1 0.02 0 0.57
63 INT342621 VEGFA Negative_regulation of Timp2 1 0.09 1.53 0.57
64 INT109307 Pik3r1 Positive_regulation of Phosphorylation of Akt1 1 0.29 0.4 0.53
65 INT194918 Csf2 Positive_regulation of Gene_expression of VEGFA 1 0.02 0.85 0.52
66 INT194919 Kitl Positive_regulation of Gene_expression of VEGFA 1 0.01 0.85 0.52
67 INT317565 Oprm1 Positive_regulation of Pik3r1 1 0.14 0.05 0.52
68 INT229095 Binding of IL1R1 and Il1r1 1 0.00 0.64 0.5
69 INT308656 Pik3r1 Positive_regulation of Nos3 1 0.02 1.8 0.5
70 INT127430 VEGFA Negative_regulation of Gene_expression of TIMP1 1 0.43 0.6 0.5
71 INT327332 VEGFA Positive_regulation of Gene_expression of Hgfac 1 0.00 2.02 0.49
72 INT288376 IL17A Regulation of VEGFA 1 0.00 1.16 0.49
73 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48
74 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 0.31 1.77 0.48
75 INT305547 VEGFA Positive_regulation of Gtf3a 2 0.00 1.83 0.48
76 INT260836 Il18 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.48
77 INT331928 Negative_regulation of Cpox Negative_regulation of VEGFA 1 0.01 0.97 0.47
78 INT314053 VEGFA Positive_regulation of Gene_expression of Mmp2 1 0.02 0.2 0.47
79 INT260843 Il6 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47
80 INT260838 Il17a Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47
81 INT147444 PDGFA Positive_regulation of Gene_expression of Ros1 2 0.00 0.95 0.46
82 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46
83 INT224698 Il17a Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46
84 INT224699 Il18 Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46
85 INT224451 Il1 Positive_regulation of Gene_expression of VEGFA 1 0.10 1.08 0.45
86 INT307675 Binding of IL1R1 and SNRNP70 1 0.02 1.05 0.45
87 INT224434 TNF Positive_regulation of VEGFA 1 0.10 2.04 0.44
88 INT311587 CXCL10 Regulation of Gene_expression of VEGFA 1 0.23 0.45 0.43
89 INT353109 Binding of VEGFA and Aes 1 0.02 3.93 0.43
90 INT311589 EGF Regulation of Gene_expression of VEGFA 1 0.18 0.51 0.43
91 INT254350 FASLG Negative_regulation of Gene_expression of VEGFA 1 0.06 0.92 0.42
92 INT153720 Binding of VEGFA and Pscs 1 0.32 3.12 0.41
93 INT295709 PTGER2 Regulation of VEGFA 1 0.01 1.61 0.41
94 INT166157 Ccr9 Positive_regulation of Pik3r1 1 0.55 2.14 0.39
95 INT304319 Ptger1 Positive_regulation of Gene_expression of Vegfa 1 0.37 1.19 0.39
96 INT285205 Binding of VEGFA and SLEB1 1 0.05 5.12 0.38
97 INT342623 Binding of VEGFA and Col18a1 1 0.02 1.15 0.37
98 INT342606 Binding of MMP14 and VEGFA 1 0.08 1.16 0.37
99 INT277353 VEGFA Regulation of Mtor 1 0.02 1.11 0.37
100 INT277355 VEGFA Regulation of Trerf1 1 0.08 1.17 0.37
101 INT277354 Gene_expression of VEGFA Regulation of Mtor 1 0.02 1.1 0.37
102 INT277352 Gene_expression of VEGFA Regulation of Trerf1 1 0.08 1.16 0.37
103 INT329449 IL17A Regulation of Gene_expression of Vegfa 1 0.28 0.63 0.36
104 INT203395 Edn1 Positive_regulation of Vegfa 1 0.06 1.59 0.35
105 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34
106 INT352231 VEGFA Negative_regulation of Cntf 1 0.04 0.22 0.34
107 INT352230 VEGFA Negative_regulation of Gene_expression of Cntf 1 0.04 0.22 0.34
108 INT352232 VEGFA Negative_regulation of Vegfa 1 0.02 0.21 0.34
109 INT288200 Tlr2 Positive_regulation of Pik3r1 1 0.05 0.24 0.33
110 INT229087 IL1R1 Negative_regulation of ACCS 1 0.03 0.86 0.33
111 INT168779 Binding of Pik3r1 and Tnf 1 0.01 0.73 0.33
112 INT110691 Lta Positive_regulation of Gene_expression of VEGFA 1 0.24 0.48 0.33
113 INT295717 VEGFA Regulation of MMP9 1 0.01 0.98 0.33
114 INT329448 IL17A Positive_regulation of Gene_expression of Vegfa 1 0.45 0.59 0.32
115 INT255740 Pik3r1 Positive_regulation of Akt1 5 0.24 2.42 0.31
116 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3
117 INT225021 PDGFB Positive_regulation of Ccl21 1 0.10 0.07 0.3
118 INT210953 Binding of VEGFA and Csf2 1 0.00 0.47 0.3
119 INT281797 Positive_regulation of Chrna4 Positive_regulation of Gene_expression of VEGFA 1 0.01 0.43 0.3
120 INT333398 CFD Negative_regulation of Gene_expression of Pdgfa 1 0.02 0.64 0.3
121 INT225026 PDGFB Positive_regulation of Gene_expression of Ccl21 1 0.10 0.07 0.3
122 INT202313 Gene_expression of PDGFB Positive_regulation of Positive_regulation of Pdgfrb 1 0.14 1 0.29
123 INT266800 Dlst Positive_regulation of Localization of VEGFA 1 0.02 0.88 0.29
124 INT185141 Pik3r1 Positive_regulation of Snrpd1 1 0.00 0.16 0.29
125 INT202314 Gene_expression of PDGFB Positive_regulation of Phosphorylation of Pdgfrb 1 0.14 1 0.29
126 INT254353 Binding of VEGFA and MMRN1 1 0.00 0.81 0.28
127 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27
128 INT320794 Binding of VEGFA and Flt4 4 0.08 3.04 0.27
129 INT103156 Tnf Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.94 0.27
130 INT287699 TNF Regulation of Binding of VEGFA 1 0.02 0.46 0.27
131 INT318551 Binding of VEGFA and Adamts1 1 0.13 1.13 0.27
132 INT285238 EGF Positive_regulation of VEGFA 1 0.01 1.55 0.27
133 INT355734 Pdgfb Regulation of Bdnf 1 0.22 1.5 0.27
134 INT224457 TNF Positive_regulation of Pdgfa 1 0.34 1.22 0.27
135 INT248318 RETN Regulation of VEGFA 1 0.00 0.43 0.26
136 INT109538 Lox Negative_regulation of Transcription of VEGFA 1 0.30 0.69 0.26
137 INT260423 IFNA1 Positive_regulation of Gene_expression of VEGFA 1 0.01 1.28 0.26
138 INT296794 Positive_regulation of Tlr2 Positive_regulation of Pik3r1 1 0.10 1.02 0.26
139 INT239570 Binding of PDGFC and AIS 1 0.04 0.9 0.26
140 INT254359 IL1B Positive_regulation of Localization of VEGFA 1 0.01 0.87 0.26
141 INT103152 TNF Positive_regulation of Positive_regulation of VEGFA 1 0.09 0.93 0.26
142 INT126886 Protein_catabolism of SP1 Negative_regulation of Gene_expression of VEGFA 1 0.03 0.49 0.26
143 INT126887 Protein_catabolism of SP4 Negative_regulation of Gene_expression of VEGFA 1 0.15 0.49 0.26
144 INT266803 Dlst Positive_regulation of VEGFA 1 0.01 0.96 0.25
145 INT109539 Lox Negative_regulation of VEGFA 1 0.40 0.68 0.25
146 INT145660 Zfp329 Positive_regulation of Gene_expression of VEGFA 1 0.00 0.51 0.25
147 INT241401 VEGFA Positive_regulation of Gene_expression of Gopc 1 0.11 0.85 0.25
148 INT332242 Binding of Egf and Pdgfa 1 0.07 0.97 0.25
149 INT256227 Binding of EDN1 and VEGFA 1 0.18 2.92 0.25
150 INT98631 Negative_regulation of VEGFA Positive_regulation of EGR1 1 0.44 0.18 0.24
151 INT98630 VEGFA Positive_regulation of EGR1 1 0.52 0.18 0.24
152 INT304323 VEGFA Positive_regulation of Gene_expression of Ptger2 1 0.27 0.16 0.23
153 INT118840 VEGFA Regulation of Positive_regulation of Mb 1 0.05 0.36 0.23
154 INT163403 VEGFA Positive_regulation of MMP2 1 0.52 0.13 0.23
155 INT323436 VEGFA Regulation of Kdr 1 0.03 0.77 0.23
156 INT304321 Ptger4 Positive_regulation of Gene_expression of VEGFA 1 0.27 0.59 0.23
157 INT304324 VEGFA Positive_regulation of Gene_expression of Ptger4 1 0.27 0.16 0.23
158 INT245866 Binding of VEGFA and Fgf1 1 0.07 0.52 0.22
159 INT118838 Gene_expression of Vegfa Positive_regulation of Gene_expression of Mb 1 0.44 0.4 0.22
160 INT9716 Binding of Egf and Pdgfc 1 0.20 0 0.22
161 INT318189 MUC5AC Regulation of Gene_expression of VEGFA 1 0.21 1.17 0.22
162 INT137611 Crh Positive_regulation of Vegfa 1 0.43 0.49 0.21
163 INT116467 Vegfa Positive_regulation of Akt1 1 0.33 1.41 0.21
164 INT311613 Binding of Slc6a4 and Pten 1 0.24 0.32 0.21
165 INT137612 Crh Positive_regulation of Positive_regulation of Vegfa 1 0.43 0.43 0.21
166 INT193035 Positive_regulation of PDGFA Positive_regulation of EGF 1 0.05 0.53 0.21
167 INT114837 Il1b Negative_regulation of Vegfa 1 0.26 3.04 0.21
168 INT163096 Tlr2 Positive_regulation of Gene_expression of VEGFA 1 0.07 0.16 0.21
169 INT116469 VEGFA Positive_regulation of Amfr 1 0.01 1.39 0.21
170 INT193025 PDGFA Positive_regulation of EGF 1 0.05 0.53 0.21
171 INT116468 VEGFA Positive_regulation of Akt1 1 0.04 1.39 0.21
172 INT116466 Vegfa Positive_regulation of Amfr 1 0.07 1.41 0.21
173 INT137610 Crh Positive_regulation of Localization of Vegfa 1 0.43 0.49 0.21
174 INT193036 EGF Positive_regulation of PDGFA 1 0.05 0.53 0.21
175 INT193032 Positive_regulation of EGF Positive_regulation of PDGFA 1 0.05 0.53 0.21
176 INT345196 Lpar2 Positive_regulation of Gene_expression of VEGFA 1 0.08 2.14 0.2
177 INT174861 Binding of FGF2 and VEGFA 1 0.34 0.59 0.2
178 INT203848 Binding of Pten and Lna1 1 0.06 0.4 0.2
179 INT236405 Mthfs Regulation of Gene_expression of VEGFA 1 0.00 0.25 0.2
180 INT287894 VEGFA Positive_regulation of Localization of BMP4 1 0.04 2.49 0.2
181 INT189553 DCN Negative_regulation of Transcription of VEGFA 1 0.06 0.78 0.2
182 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19
183 INT175727 IL1B Regulation of VEGFA 2 0.04 0.7 0.19
184 INT280275 Tgfb1 Positive_regulation of VEGFA 1 0.02 2.46 0.19
185 INT282866 Bpifa2 Negative_regulation of Gene_expression of VEGFA 1 0.11 1.14 0.19
186 INT224688 Pten Regulation of Akt1 1 0.04 1.12 0.19
187 INT280268 Tgfb1 Positive_regulation of Gene_expression of Vegfa 1 0.06 1.81 0.19
188 INT332245 Pdgfa Positive_regulation of Stat6 1 0.07 1.22 0.19
189 INT281477 Binding of Pten and Th 1 0.28 0.4 0.19
190 INT280266 Tgfb1 Positive_regulation of Vegfa 1 0.09 1.8 0.19
191 INT110692 Lta Regulation of Gene_expression of VEGFA 1 0.14 0.28 0.19
192 INT355733 Pdgfb Regulation of Transcription of Bdnf 1 0.10 0.86 0.19
193 INT280274 Tgfb1 Positive_regulation of Gene_expression of VEGFA 1 0.02 2.58 0.19
194 INT304325 Positive_regulation of Ptger2 Positive_regulation of Gene_expression of VEGFA 1 0.25 0.23 0.19
195 INT192333 PDGFA Positive_regulation of Gene_expression of FN1 2 0.11 1.26 0.18
196 INT337697 FGF2 Regulation of VEGFA 1 0.03 0.51 0.18
197 INT113809 Negative_regulation of Cpox Negative_regulation of Gene_expression of VEGFA 1 0.02 0.97 0.18
198 INT337698 VEGFA Regulation of FGFR1 1 0.09 0.51 0.18
199 INT314038 THL Negative_regulation of Pik3r1 1 0.14 0.78 0.18
200 INT224680 Tgfb1 Negative_regulation of Pten 1 0.00 1.19 0.18

Single Events

The table below shows the top 100 pain related interactions that have been reported for platelet-derived growth factor receptor binding. They are ordered first by their pain relevance and then by number of times they were reported in platelet-derived growth factor receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
2 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
3 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
4 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
5 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
6 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
7 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
8 INT48692 Binding of VEGFA 345 0.48 210.3 21.31
9 INT112029 Positive_regulation of Pik3r1 90 0.67 38.76 20.95
10 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14
11 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03
12 INT112027 Gene_expression of Pik3r1 58 0.75 30.9 15.95
13 INT96775 Gene_expression of Pdgfa 42 0.54 29.78 15.46
14 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89
15 INT114420 Negative_regulation of Pik3r1 67 0.54 34.86 12.82
16 INT151168 Gene_expression of Pten 60 0.78 35.63 10.54
17 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39
18 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9
19 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63
20 INT111545 Phosphorylation of VEGFA 50 0.76 22.19 5.88
21 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78
22 INT96778 Positive_regulation of Pdgfa 22 0.46 12.7 5.31
23 INT116744 Binding of Pik3r1 22 0.36 12.77 5.01
24 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9
25 INT36030 Gene_expression of Il1r1 16 0.68 11.42 4.87
26 INT99690 Negative_regulation of Positive_regulation of VEGFA 30 0.58 14.56 4.79
27 INT116748 Positive_regulation of Gene_expression of Pik3r1 18 0.49 9.83 4.63
28 INT74531 Regulation of PDGFB 14 0.26 7.57 4.38
29 INT116747 Regulation of Pik3r1 18 0.60 9.33 4.34
30 INT181596 Binding of IL1R1 9 0.36 7.99 4.32
31 INT103153 Positive_regulation of Transcription of VEGFA 34 0.69 22.16 4.22
32 INT156097 Negative_regulation of Localization of VEGFA 70 0.58 34.96 4.17
33 INT96776 Positive_regulation of Gene_expression of Pdgfa 8 0.40 7.79 3.93
34 INT118835 Positive_regulation of Vegfa 18 0.59 11.2 3.91
35 INT276198 Positive_regulation of Pten 1 0.52 5.02 3.88
36 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75
37 INT151171 Positive_regulation of Pten 20 0.55 13.3 3.54
38 INT70897 Positive_regulation of Gene_expression of PDGFB 15 0.57 13.04 3.52
39 INT96777 Localization of Pdgfa 12 0.79 5.86 3.52
40 INT70895 Localization of PDGFB 20 0.52 8.98 3.4
41 INT208291 Negative_regulation of Pten 2 0.44 5.42 3.36
42 INT22375 Localization of PDGFA 21 0.75 15.46 3.25
43 INT99687 Negative_regulation of Transcription of VEGFA 17 0.43 10.3 3.25
44 INT111547 Negative_regulation of Phosphorylation of VEGFA 13 0.42 5.08 3.22
45 INT165911 Localization of Pik3r1 15 0.51 7.94 3.2
46 INT70885 Gene_expression of Pdgfb 48 0.67 42.27 3.19
47 INT91173 Gene_expression of Pdgfrb 33 0.65 32.55 3.09
48 INT137609 Localization of Vegfa 22 0.78 14.67 3.01
49 INT64437 Gene_expression of IL1R1 9 0.65 6.22 2.99
50 INT126966 Positive_regulation of IL1R1 8 0.67 6.93 2.84
51 INT271599 Phosphorylation of Pdgfa 1 0.11 2.55 2.81
52 INT184477 Negative_regulation of Pten 27 0.59 15.61 2.8
53 INT119383 Gene_expression of Pten 11 0.59 10.33 2.73
54 INT43719 Positive_regulation of Vegfa 21 0.69 5.15 2.64
55 INT172963 Negative_regulation of Pdgfa 11 0.21 12.94 2.64
56 INT74527 Positive_regulation of PDGFB 14 0.38 13.31 2.54
57 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5
58 INT137908 Phosphorylation of Pdgfrb 14 0.81 8.44 2.45
59 INT223080 Binding of Pdgfa 8 0.18 7.21 2.44
60 INT113164 Regulation of Regulation of VEGFA 6 0.36 5.96 2.43
61 INT109305 Phosphorylation of Pik3r1 13 0.53 5.69 2.32
62 INT123528 Negative_regulation of Gene_expression of Vegfa 10 0.57 7.08 2.31
63 INT36029 Negative_regulation of Il1r1 9 0.41 4.64 2.3
64 INT43723 Regulation of Vegfa 9 0.34 4.96 2.28
65 INT146945 Positive_regulation of Lyn 6 0.49 2.81 2.25
66 INT163545 Gene_expression of PDGFRB 39 0.78 25.5 2.2
67 INT114421 Positive_regulation of Positive_regulation of Pik3r1 9 0.49 4.07 2.13
68 INT224615 Negative_regulation of Gene_expression of Pten 7 0.59 2.99 2.09
69 INT276201 Phosphorylation of Pten 1 0.61 1.31 2.08
70 INT105247 Positive_regulation of Gene_expression of Vegfa 12 0.67 12.07 2.05
71 INT136818 Positive_regulation of Phosphorylation of VEGFA 4 0.46 0.81 2.02
72 INT137906 Positive_regulation of Phosphorylation of Pdgfrb 6 0.50 2.55 1.94
73 INT144020 Positive_regulation of Pdgfrb 30 0.69 24.8 1.92
74 INT122195 Regulation of Localization of VEGFA 13 0.57 10.61 1.92
75 INT67895 Negative_regulation of IL1R1 7 0.57 5.76 1.9
76 INT52618 Positive_regulation of Pdgfc 3 0.33 0.82 1.9
77 INT124559 Gene_expression of Il1r1 4 0.54 2.14 1.89
78 INT85492 Localization of IL1R1 6 0.72 2.44 1.85
79 INT118833 Positive_regulation of Gene_expression of Vegfa 11 0.65 8.14 1.7
80 INT12442 Localization of Vegfa 11 0.73 4.85 1.68
81 INT276171 Positive_regulation of Gene_expression of Pten 3 0.52 7.24 1.64
82 INT105248 Negative_regulation of Vegfa 8 0.47 6.19 1.61
83 INT151169 Positive_regulation of Gene_expression of Pten 15 0.45 12.88 1.53
84 INT89116 Regulation of Positive_regulation of VEGFA 8 0.43 6.62 1.5
85 INT74528 Negative_regulation of PDGFB 11 0.40 10.34 1.48
86 INT52873 Localization of Il1r1 4 0.56 1.28 1.48
87 INT74530 Transcription of PDGFB 7 0.65 4.56 1.47
88 INT138699 Gene_expression of Pdgfc 5 0.30 3.32 1.46
89 INT228249 Binding of Pten 7 0.48 3.26 1.45
90 INT112109 Gene_expression of FIGF 13 0.31 8.31 1.44
91 INT281470 Regulation of Gene_expression of Pten 4 0.39 1.13 1.42
92 INT276196 Positive_regulation of Phosphorylation of Pten 1 0.38 0.19 1.41
93 INT109536 Negative_regulation of Vegfa 15 0.46 10.35 1.39
94 INT109301 Positive_regulation of Phosphorylation of Pik3r1 5 0.42 1.45 1.38
95 INT276181 Negative_regulation of Gene_expression of Pten 1 0.44 2.48 1.37
96 INT44529 Positive_regulation of Pdgfb 11 0.43 7.98 1.36
97 INT239575 Regulation of PDGFC 1 0.07 4.93 1.3
98 INT95116 Negative_regulation of PDGFA 24 0.57 19.56 1.29
99 INT144019 Negative_regulation of Pdgfrb 21 0.58 14.93 1.26
100 INT192349 Negative_regulation of Gene_expression of PDGFB 5 0.31 2.64 1.25
101 INT171057 Gene_expression of PDGFC 7 0.15 5.84 1.22
102 INT61094 Gene_expression of Pdgfc 3 0.09 1.97 1.21
103 INT190014 Regulation of Pten 8 0.62 6.03 1.2
104 INT137607 Positive_regulation of Localization of Vegfa 7 0.49 3.72 1.18
105 INT188376 Negative_regulation of Gene_expression of Vegfa 5 0.30 5.29 1.18
106 INT70886 Positive_regulation of Gene_expression of Pdgfb 13 0.45 12.57 1.17
107 INT124560 Negative_regulation of Il1r1 2 0.07 0.77 1.14
108 INT210392 Regulation of PDGFA 10 0.36 11.41 1.12
109 INT98489 Binding of Il1r1 3 0.36 1.46 1.06
110 INT274898 Positive_regulation of Positive_regulation of Lyn 1 0.35 1.51 1.05
111 INT160235 Positive_regulation of Gene_expression of FIGF 4 0.20 5.53 1
112 INT112717 Negative_regulation of Binding of VEGFA 21 0.56 11.07 0.99
113 INT78014 Negative_regulation of ITGA5 1 0.01 1.71 0.98
114 INT146939 Negative_regulation of Lyn 3 0.53 2.97 0.95
115 INT96774 Positive_regulation of Localization of Pdgfa 3 0.69 1.21 0.95
116 INT46485 Positive_regulation of Pdgfc 3 0.18 2.74 0.92
117 INT188317 Positive_regulation of Gene_expression of PDGFA 15 0.46 12.7 0.91
118 INT149383 Binding of Lyn 1 0.36 1.14 0.91
119 INT271598 Negative_regulation of Phosphorylation of Pdgfa 1 0.05 0.77 0.88
120 INT271597 Regulation of Gene_expression of Pdgfa 1 0.05 0.81 0.87
121 INT17807 Positive_regulation of PDGFC 4 0.06 3.28 0.86
122 INT276177 Regulation of Gene_expression of Pten 1 0.34 1.51 0.84
123 INT211488 Regulation of Binding of VEGFA 5 0.43 3.72 0.83
124 INT119102 Gene_expression of PDGFRA 13 0.75 11.99 0.81
125 INT288191 Positive_regulation of Localization of Pik3r1 4 0.15 1.27 0.81
126 INT36028 Positive_regulation of Gene_expression of Il1r1 4 0.40 1.82 0.81
127 INT151626 Negative_regulation of Gene_expression of Il1r1 1 0.20 1.33 0.8
128 INT173082 Positive_regulation of Binding of VEGFA 20 0.48 11.16 0.79
129 INT171096 Transcription of PDGFA 5 0.47 4.42 0.79
130 INT239574 Binding of PDGFC 1 0.04 3.29 0.79
131 INT112947 Regulation of Il1r1 2 0.24 0.36 0.78
132 INT95118 Negative_regulation of Gene_expression of PDGFA 4 0.54 5.03 0.76
133 INT112945 Transcription of Il1r1 1 0.39 0.32 0.76
134 INT164756 Negative_regulation of PDGFRB 32 0.57 21.69 0.72
135 INT143445 Protein_catabolism of VEGFA 12 0.85 4.14 0.72
136 INT12443 Regulation of Localization of Vegfa 2 0.20 0 0.72
137 INT202307 Regulation of Gene_expression of PDGFB 2 0.26 1.24 0.71
138 INT171364 Localization of Pdgfrb 6 0.37 4.98 0.68
139 INT91172 Positive_regulation of Gene_expression of Pdgfrb 4 0.38 2.83 0.68
140 INT195104 Positive_regulation of Il1r1 4 0.40 2.18 0.68
141 INT276199 Binding of Pten 2 0.30 0.4 0.67
142 INT171380 Positive_regulation of Localization of Pdgfrb 1 0.21 0.48 0.66
143 INT166456 Negative_regulation of Gene_expression of Pik3r1 4 0.41 1.72 0.64
144 INT64438 Regulation of IL1R1 2 0.26 1.62 0.64
145 INT340625 Protein_catabolism of Vegfa 1 0.05 1.61 0.64
146 INT210390 Binding of PDGFA 12 0.36 6.78 0.63
147 INT174868 Regulation of Negative_regulation of VEGFA 4 0.43 4.51 0.63
148 INT276179 Regulation of Pten 1 0.46 0.81 0.63
149 INT74529 Binding of PDGFB 13 0.36 7.41 0.62
150 INT135666 Negative_regulation of Negative_regulation of Pik3r1 2 0.29 0.3 0.6
151 INT277699 Gene_expression of Pdgfb 5 0.20 4.84 0.59
152 INT117091 Positive_regulation of Lyn 1 0.49 0.41 0.56
153 INT174873 Regulation of Transcription of VEGFA 8 0.43 3.71 0.55
154 INT202306 Negative_regulation of Localization of PDGFB 2 0.25 0.76 0.55
155 INT172964 Binding of Vegfa 14 0.47 10.62 0.53
156 INT105677 Binding of Vegfa 7 0.37 5.22 0.51
157 INT144024 Negative_regulation of Phosphorylation of Pdgfrb 6 0.42 3.48 0.51
158 INT74724 Regulation of Ptprj 2 0.05 0.35 0.51
159 INT198048 Protein_catabolism of PDGFA 2 0.28 2.05 0.5
160 INT224442 Negative_regulation of Gene_expression of Pdgfa 2 0.30 2.48 0.5
161 INT343801 Negative_regulation of Transcription of PDGFA 1 0.29 0.37 0.5
162 INT74725 Localization of Ptprj 1 0.14 0.15 0.5
163 INT202309 Regulation of Localization of PDGFB 1 0.36 0.92 0.49
164 INT73200 Positive_regulation of PDGFRB 10 0.67 9.67 0.48
165 INT223081 Negative_regulation of Gene_expression of Pdgfb 2 0.37 3.07 0.47
166 INT276174 Regulation of Negative_regulation of Pten 1 0.34 0.63 0.47
167 INT313617 Positive_regulation of Pdgfb 4 0.35 1.53 0.46
168 INT67894 Transcription of IL1R1 4 0.67 2.17 0.45
169 INT107323 Regulation of Gene_expression of Pdgfc 1 0.01 0.96 0.44
170 INT192342 Phosphorylation of PDGFRB 11 0.80 1.68 0.43
171 INT247568 Negative_regulation of Negative_regulation of VEGFA 5 0.41 5.35 0.43
172 INT276180 Positive_regulation of Negative_regulation of Pten 1 0.35 0.89 0.43
173 INT70884 Localization of Pdgfb 8 0.35 6.22 0.42
174 INT268877 Regulation of Gene_expression of Vegfa 2 0.58 4.73 0.42
175 INT276202 Negative_regulation of Protein_catabolism of Pten 1 0.32 0.78 0.42
176 INT152023 Regulation of Vegfa 4 0.52 3.99 0.41
177 INT43720 Regulation of Positive_regulation of Vegfa 1 0.03 0.41 0.41
178 INT276204 Protein_catabolism of Pten 1 0.75 0.77 0.41
179 INT43722 Positive_regulation of Regulation of Vegfa 1 0.06 0.41 0.41
180 INT203816 Localization of Pten 4 0.75 1.37 0.4
181 INT76143 Positive_regulation of Regulation of PDGFB 1 0.01 0.08 0.4
182 INT74532 Positive_regulation of Transcription of PDGFB 1 0.57 0.73 0.4
183 INT129849 Positive_regulation of Localization of Vegfa 1 0.46 0.35 0.39
184 INT192344 Negative_regulation of Phosphorylation of PDGFRB 4 0.54 1.26 0.38
185 INT112110 Positive_regulation of FIGF 3 0.18 5.28 0.37
186 INT317875 Binding of Pdgfb 3 0.10 1.15 0.36
187 INT153261 Positive_regulation of Localization of PDGFB 2 0.37 1.98 0.36
188 INT168766 Positive_regulation of Binding of Pik3r1 3 0.21 1.54 0.35
189 INT151167 Phosphorylation of Pten 3 0.72 1.69 0.35
190 INT151166 Positive_regulation of Phosphorylation of Pten 2 0.40 1.54 0.35
191 INT201841 Negative_regulation of Negative_regulation of IL1R1 1 0.01 0.78 0.34
192 INT229092 Positive_regulation of Localization of IL1R1 1 0.14 0.41 0.34
193 INT61095 Positive_regulation of Gene_expression of Pdgfc 1 0.07 0.47 0.34
194 INT281469 Transcription of Pten 2 0.72 1.12 0.32
195 INT281474 Regulation of Transcription of Pten 1 0.62 0.35 0.32
196 INT332231 Positive_regulation of Positive_regulation of Pdgfa 1 0.16 0.83 0.31
197 INT156411 Gene_expression of Pdgfra 8 0.75 5.5 0.3
198 INT192348 Positive_regulation of Gene_expression of PDGFRB 5 0.64 3.57 0.3
199 INT212985 Negative_regulation of Positive_regulation of Pik3r1 3 0.19 3.28 0.3
200 INT185119 Regulation of Positive_regulation of Pik3r1 3 0.13 0.45 0.3
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