GO:0005164

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Name tumor necrosis factor receptor binding
Categary Function
Go Slim No
Go Link GO:0005164
Unique Molecular Interactions 2142
Total Molecular Interactions 3035
Total Single Events 29658
Pain Genes Associated 46

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for tumor necrosis factor receptor binding. They are ordered first by their pain relevance and then by number of times they were reported for tumor necrosis factor receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62
2 INT140935 Binding of Cd40lg and Cd40 1 0.30 6.34 5.61
3 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
4 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01
5 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
6 INT220623 Binding of Stat1 and Bace1 11 0.25 10.33 3.81
7 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
8 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11
9 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
10 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
11 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
12 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
13 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
14 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
15 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
16 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
17 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
18 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
19 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
20 INT319581 Binding of PIAS1 and TNFSF14 1 0.02 1.58 2.13
21 INT83425 Binding of CD40LG and IGHG3 11 0.21 4.56 2.09
22 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
23 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
24 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
25 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
26 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
27 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
28 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
29 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
30 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
31 INT139190 Binding of Fadd and Fas 4 0.38 2.65 1.71
32 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
33 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
34 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
35 INT150232 Samhd1 Positive_regulation of Gene_expression of TNFSF13B 1 0.01 1.74 1.67
36 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
37 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
38 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
39 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
40 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
41 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
42 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
43 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
44 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
45 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
46 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
47 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
48 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
49 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
50 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
51 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
52 INT264327 IL-17 Positive_regulation of Gene_expression of Tnfsf11 1 0.07 3.19 1.33
53 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
54 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
55 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
56 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
57 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26
58 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
59 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22
60 INT70028 LTA Regulation of PRF1 1 0.02 1.42 1.21
61 INT70036 LTA Regulation of Negative_regulation of IL10 1 0.03 1.42 1.21
62 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
63 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
64 INT70042 LTA Regulation of Negative_regulation of PRF1 1 0.02 1.42 1.21
65 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
66 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
67 INT70041 LTA Regulation of IL10 1 0.03 1.42 1.21
68 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2
69 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
70 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
71 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
72 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
73 INT72754 Adamts7 Negative_regulation of TNF 1 0.28 1.64 1.13
74 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
75 INT107264 Binding of TNF and NCR3 1 0.30 1.42 1.1
76 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
77 INT107266 Binding of HLA-DRB1 and TNF 1 0.29 1.41 1.1
78 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1
79 INT107267 Binding of HLA-A and TNF 1 0.34 1.41 1.1
80 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
81 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
82 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
83 INT156238 Binding of F2rl1 and Tnfsf14 1 0.08 2.85 1.08
84 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
85 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
86 INT119108 Binding of LTBR and TNF 2 0.15 1.47 1.07
87 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
88 INT297491 Positive_regulation of Lta Positive_regulation of Ltp 1 0.00 0.16 1.06
89 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05
90 INT131853 CD40 Negative_regulation of Gene_expression of CD40LG 1 0.09 1.54 1.05
91 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05
92 INT152504 Binding of CR1 and Tnf 1 0.00 0.49 1.04
93 INT338894 TNFSF14 Negative_regulation of Gsk3a 1 0.00 0.54 1.04
94 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04
95 INT156245 NFKB1 Positive_regulation of Regulation of TNF 1 0.45 0.76 1.03
96 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02
97 INT98555 Oprm1 Positive_regulation of Casp8 1 0.51 0.36 1.02
98 INT338892 TNFSF14 Regulation of Abat 1 0.00 0.61 1.01
99 INT338895 TNFSF14 Regulation of Regulation of Abat 1 0.00 0.62 1.01
100 INT91813 Binding of FAS and FASLG 4 0.23 9.89 0.99
101 INT308804 Pld1 Positive_regulation of TNF 1 0.05 2.42 0.99
102 INT274895 Positive_regulation of Cbr2 Negative_regulation of Gene_expression of TNF 1 0.06 1.21 0.99
103 INT93114 Positive_regulation of Lta Positive_regulation of Gene_expression of Ltp 1 0.06 0.08 0.99
104 INT129216 Negative_regulation of RYBP Positive_regulation of Tnf 1 0.01 1.24 0.98
105 INT140936 Binding of Cd40lg and Ean5 1 0.07 1.03 0.98
106 INT182022 TNF Positive_regulation of Gene_expression of Tnfrsf11b 1 0.06 1.56 0.98
107 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98
108 INT133616 Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
109 INT133615 Regulation of Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
110 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
111 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
112 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
113 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96
114 INT133617 Fas Positive_regulation of Fadd 1 0.48 0.07 0.96
115 INT133652 Epo Negative_regulation of Gene_expression of TNF 1 0.35 2.64 0.96
116 INT171264 TNF Positive_regulation of MMP1 2 0.10 2.05 0.95
117 INT188805 TNF Positive_regulation of Gene_expression of Crp 1 0.15 2.96 0.95
118 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
119 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
120 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94
121 INT139330 Binding of SGCG and Stat1 1 0.37 0.75 0.94
122 INT129211 RYBP Positive_regulation of Gene_expression of Tnf 1 0.01 1.04 0.94
123 INT338893 TNFSF14 Positive_regulation of Gene_expression of Gria1 1 0.07 0.59 0.94
124 INT155259 RUNX1 Negative_regulation of Tnf 1 0.00 1.48 0.93
125 INT165280 Tnf Positive_regulation of Gene_expression of Nos2 1 0.24 1.02 0.91
126 INT254242 TNF Positive_regulation of Gene_expression of DKK1 1 0.14 1.24 0.91
127 INT256646 Tnf Positive_regulation of Positive_regulation of Nfkb1 1 0.22 1.83 0.9
128 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 0.01 1.66 0.9
129 INT211128 Binding of P4HB and TNF 1 0.09 0.97 0.9
130 INT211129 Negative_regulation of Binding of P4HB and TNF 1 0.10 0.97 0.9
131 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
132 INT80132 Binding of HLA-B and TNF 1 0.04 1.15 0.89
133 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89
134 INT167466 Ccdc80 Negative_regulation of Tnf 1 0.01 0.76 0.88
135 INT134311 Tnf Positive_regulation of Protein_catabolism of Nfkbia 1 0.18 0.57 0.88
136 INT116556 Olr1627 Negative_regulation of Regulation of Tnf 1 0.01 1.52 0.87
137 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86
138 INT97795 IRF6 Positive_regulation of Localization of TNF 3 0.09 1.57 0.86
139 INT160413 Tat Positive_regulation of Gene_expression of Cd40lg 1 0.50 0.98 0.86
140 INT152868 Tnf Regulation of Gene_expression of Trpv1 1 0.27 0.25 0.86
141 INT130769 FASLG Negative_regulation of Binding of FAS 1 0.10 0.66 0.86
142 INT125234 Positive_regulation of Binding of BCR and CD40LG 1 0.31 0.76 0.86
143 INT167947 Binding of STAT1 and Oprm1 1 0.00 0 0.86
144 INT110315 Negative_regulation of ALOX5 Negative_regulation of Gene_expression of TNF 1 0.47 0.74 0.85
145 INT125233 Binding of BCR and CD40LG 1 0.23 0.75 0.85
146 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
147 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84
148 INT196638 TNF Positive_regulation of F2RL1 2 0.09 1.52 0.84
149 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 1 0.16 1.44 0.84
150 INT238641 Binding of TNF and Ifx 1 0.07 0.86 0.84
151 INT238642 Binding of TNF and Ada 1 0.03 0.86 0.84
152 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83
153 INT149626 Il1b Regulation of Gene_expression of Tnf 1 0.41 0.83 0.83
154 INT102201 Tnf Regulation of Il1b 3 0.39 2.57 0.82
155 INT162071 Gene_expression of MC1R Negative_regulation of Gene_expression of TNF 1 0.41 0.34 0.82
156 INT66206 Negative_regulation of TNF Positive_regulation of NFKB1 2 0.53 1.71 0.81
157 INT156239 Tnfsf14 Positive_regulation of F2rl1 1 0.09 2.4 0.81
158 INT140922 Btnl2 Negative_regulation of EDA 1 0.00 0.88 0.8
159 INT126555 Binding of Ighg1 and Tnf 1 0.35 2.2 0.8
160 INT147755 Binding of GNRH1 and TNF 1 0.32 2.37 0.79
161 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78
162 INT188531 Binding of TNF and PDXK 1 0.03 1.99 0.78
163 INT102163 Binding of TNF and Mmp9 1 0.12 0.88 0.78
164 INT306259 HDAC9 Negative_regulation of Gene_expression of TNF 1 0.21 0.89 0.78
165 INT102161 Binding of TNF and Mmp2 1 0.10 0.88 0.78
166 INT306258 HDAC4 Negative_regulation of Gene_expression of TNF 1 0.09 0.89 0.78
167 INT130138 TNF Negative_regulation of Gene_expression of S100A10 1 0.06 1.32 0.78
168 INT187229 Binding of Tnfsf11 and Insrr 1 0.00 2.06 0.78
169 INT102162 Binding of TNF and Adam17 1 0.14 0.88 0.78
170 INT207391 Il17a Positive_regulation of Gene_expression of Tnfsf11 2 0.05 1.19 0.77
171 INT296797 Tlr9 Regulation of Positive_regulation of TNF 1 0.03 1.37 0.77
172 INT296798 Gopc Regulation of Positive_regulation of TNF 1 0.01 1.37 0.77
173 INT152869 Tnf Positive_regulation of Gene_expression of Trpv1 1 0.46 0.48 0.77
174 INT209883 TNF Positive_regulation of Gene_expression of TNFRSF11A 1 0.20 1.83 0.77
175 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76
176 INT149192 TNF Positive_regulation of Gene_expression of VCAM1 3 0.57 1.4 0.76
177 INT135180 IL1B Positive_regulation of Gene_expression of TNFSF11 2 0.76 1.73 0.75
178 INT26497 TNF Positive_regulation of Gene_expression of MMP2 1 0.44 1.5 0.75
179 INT113472 TNF Positive_regulation of Localization of MMP14 1 0.47 0.45 0.75
180 INT308176 TNF Regulation of Tnfrsf1a 1 0.05 1.19 0.75
181 INT354455 Il11 Negative_regulation of Gene_expression of Tnf 1 0.31 1.21 0.74
182 INT301141 Nsa2 Positive_regulation of TNF 1 0.01 0.6 0.74
183 INT301142 Negative_regulation of Nsa2 Positive_regulation of TNF 1 0.01 0.6 0.74
184 INT4875 TNF Regulation of MME 1 0.51 0.71 0.74
185 INT86657 TNF Regulation of H2-Ab1 1 0.02 0.84 0.74
186 INT190174 TNF Positive_regulation of MMP12 1 0.27 0.08 0.74
187 INT96301 Olr1742 Negative_regulation of Gene_expression of Tnf 1 0.14 0 0.74
188 INT211127 Regulation of Binding of MTX1 and TNF 1 0.22 0.71 0.74
189 INT211130 Binding of MTX1 and TNF 1 0.18 0.7 0.73
190 INT228499 Binding of FAS and Fasl 1 0.15 2.75 0.73
191 INT172147 Binding of IL15 and TNF 2 0.05 1.19 0.72
192 INT150992 Sfpq Negative_regulation of Gene_expression of Tnf 1 0.03 0.69 0.72
193 INT51006 PDYN Positive_regulation of TNF 1 0.11 0.84 0.72
194 INT236364 CD40LG Positive_regulation of Gene_expression of IL6 1 0.25 1.37 0.72
195 INT146463 TNFSF10 Positive_regulation of NFKB1 2 0.08 2.45 0.71
196 INT187231 Negative_regulation of Binding of Tnfrsf11a and Tnfsf11 1 0.18 1.8 0.71
197 INT146462 TNFSF10 Positive_regulation of Gene_expression of TNFRSF10D 1 0.27 1.45 0.71
198 INT117535 SND1 Positive_regulation of Gene_expression of TNF 1 0.06 0.29 0.71
199 INT113499 TNF Positive_regulation of Gene_expression of BHLHE23 1 0.25 0.1 0.71
200 INT159963 Tnf Positive_regulation of Localization of Il6 1 0.12 2.32 0.71

Single Events

The table below shows the top 100 pain related interactions that have been reported for tumor necrosis factor receptor binding. They are ordered first by their pain relevance and then by number of times they were reported in tumor necrosis factor receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
3 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
4 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
5 INT6852 Localization of TNF 883 0.81 705.95 270.84
6 INT6481 Binding of TNF 624 0.48 510.2 214.82
7 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
8 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
9 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
10 INT9660 Regulation of TNF 363 0.62 312.94 139.99
11 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
12 INT10166 Localization of Tnf 237 0.81 153.95 88.64
13 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
14 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
15 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
16 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
17 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
18 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
19 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
20 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
21 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
22 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23
23 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
24 INT13354 Transcription of TNF 108 0.72 85.81 42.32
25 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
26 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66
27 INT35406 Localization of Tnf 94 0.81 64.63 31.65
28 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
29 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11
30 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
31 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
32 INT116856 Gene_expression of TNFSF10 110 0.75 115.76 21.48
33 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
34 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
35 INT7994 Gene_expression of Lta 113 0.67 69.81 19.59
36 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
37 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
38 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46
39 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
40 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
41 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
42 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
43 INT10173 Binding of Tnf 45 0.48 35.6 14.32
44 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
45 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
46 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
47 INT93620 Positive_regulation of Gene_expression of Fasl 51 0.66 59.45 12.04
48 INT24816 Binding of CD40LG 68 0.47 45.48 11.56
49 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75
50 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64
51 INT93533 Positive_regulation of Tnfsf11 53 0.50 36.93 10.53
52 INT130867 Gene_expression of TNFSF11 106 0.77 45.15 10.34
53 INT98130 Positive_regulation of CASP8 79 0.67 65.29 10.08
54 INT44602 Gene_expression of TNFSF13B 37 0.75 30.98 9.96
55 INT7995 Positive_regulation of Lta 28 0.66 14.98 9.8
56 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78
57 INT86851 Gene_expression of Faslg 45 0.75 24.42 9.21
58 INT85966 Gene_expression of Cd40lg 50 0.73 30.9 9.11
59 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
60 INT178174 Gene_expression of Tnfsf10 78 0.76 56.83 8.64
61 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54
62 INT13539 Gene_expression of LTA 39 0.62 22.55 8.07
63 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89
64 INT49490 Positive_regulation of Transcription of TNF 19 0.70 14.76 7.58
65 INT95133 Gene_expression of FASLG 38 0.75 44.09 7.51
66 INT68299 Binding of Tnf 17 0.39 12.55 7.49
67 INT119729 Binding of Tnfsf11 31 0.35 24.02 7.45
68 INT104207 Positive_regulation of Gene_expression of Tnfsf11 43 0.69 25.8 7.35
69 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
70 INT138922 Positive_regulation of Stat1 57 0.69 28.35 7.2
71 INT1124 Negative_regulation of CD40LG 53 0.57 36.26 7
72 INT99942 Positive_regulation of Fasl 37 0.68 32.61 6.92
73 INT4431 Negative_regulation of Eda 10 0.46 3.53 6.81
74 INT69985 Positive_regulation of Negative_regulation of TNF 21 0.50 13.26 6.31
75 INT83451 Positive_regulation of Gene_expression of CD40LG 26 0.60 22.81 6.25
76 INT136555 Negative_regulation of Tnfsf11 31 0.55 22.23 6.23
77 INT163756 Phosphorylation of Stat1 45 0.82 14.51 6.11
78 INT172084 Positive_regulation of Binding of TNF 21 0.50 15.31 6.06
79 INT67060 Negative_regulation of Transcription of TNF 17 0.59 12.94 5.88
80 INT138915 Gene_expression of Stat1 144 0.77 69.53 5.85
81 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64
82 INT15542 Negative_regulation of CASP8 20 0.41 17.3 5.63
83 INT118870 Positive_regulation of STAT1 36 0.67 26.18 5.46
84 INT58145 Positive_regulation of Localization of Tnf 20 0.67 13.33 5.44
85 INT150528 Positive_regulation of Gene_expression of TNFSF10 26 0.67 30.71 5.43
86 INT45753 Localization of CD40LG 45 0.79 32.31 5.28
87 INT88019 Positive_regulation of Gene_expression of Faslg 16 0.67 11.31 5.05
88 INT92054 Positive_regulation of Transcription of Tnf 8 0.50 4.93 5.05
89 INT55698 Regulation of Binding of TNF 13 0.44 8.98 4.74
90 INT149093 Positive_regulation of TNFSF10 31 0.49 34.61 4.56
91 INT85965 Binding of Cd40lg 26 0.45 16.76 4.52
92 INT56404 Gene_expression of EDA 16 0.75 7.09 4.24
93 INT26239 Positive_regulation of Gene_expression of Lta 12 0.36 8.86 4.22
94 INT134646 Gene_expression of Tnfsf11 19 0.69 14.77 4.16
95 INT5148 Regulation of CD40LG 25 0.44 21.58 4.05
96 INT133602 Positive_regulation of Fadd 2 0.54 0.38 4.02
97 INT66754 Negative_regulation of Transcription of Tnf 11 0.43 8.43 3.93
98 INT23088 Phosphorylation of Tnf 15 0.79 9.85 3.82
99 INT172173 Protein_catabolism of TNF 16 0.96 9.95 3.79
100 INT44717 Gene_expression of TNFSF14 12 0.75 13.44 3.72
101 INT140933 Binding of Cd40lg 1 0.38 4.2 3.6
102 INT133604 Negative_regulation of Fadd 4 0.57 0.81 3.5
103 INT140931 Gene_expression of Cd40lg 5 0.61 5.2 3.33
104 INT133768 Regulation of Fasl 10 0.44 10.24 3.32
105 INT85971 Positive_regulation of Gene_expression of Cd40lg 14 0.66 7.61 3.29
106 INT125237 Negative_regulation of Gene_expression of CD40LG 16 0.54 9.9 3.27
107 INT70049 Positive_regulation of Gene_expression of LTA 7 0.32 4.66 3.25
108 INT65427 Regulation of Positive_regulation of Tnf 7 0.60 3.49 3.22
109 INT184060 Negative_regulation of Stat1 28 0.58 17.44 3.19
110 INT188406 Binding of Fasl 19 0.44 24.67 3.17
111 INT85970 Positive_regulation of Cd40lg 21 0.53 8.51 3.16
112 INT130865 Positive_regulation of TNFSF11 29 0.69 12.82 2.99
113 INT49994 Gene_expression of Lta 9 0.64 6.94 2.98
114 INT163780 Gene_expression of Nucb2 11 0.77 5.1 2.94
115 INT98554 Positive_regulation of Casp8 20 0.67 21.32 2.9
116 INT93531 Negative_regulation of Gene_expression of Tnfsf11 15 0.43 7.74 2.84
117 INT99129 Negative_regulation of LTB 5 0.57 0.7 2.84
118 INT95049 Negative_regulation of Regulation of Tnf 4 0.42 1.64 2.84
119 INT94327 Phosphorylation of Stat1 9 0.80 2.06 2.8
120 INT132846 Localization of Tnfsf11 17 0.69 10.28 2.78
121 INT119839 Gene_expression of STAT1 17 0.75 8.36 2.7
122 INT75736 Regulation of Localization of Tnf 6 0.62 4.61 2.67
123 INT62049 Transcription of Lta 1 0.18 6.93 2.67
124 INT171346 Gene_expression of TNFSF12 7 0.58 4.19 2.62
125 INT15543 Gene_expression of CASP8 32 0.75 25.6 2.61
126 INT98607 Regulation of Regulation of TNF 8 0.44 6.95 2.56
127 INT150218 Transcription of TNFSF13B 1 0.08 2.62 2.55
128 INT158827 Positive_regulation of FADD 7 0.43 2.6 2.54
129 INT107302 Negative_regulation of Gene_expression of Fasl 7 0.42 8.52 2.54
130 INT21248 Localization of Lta 15 0.59 5.16 2.5
131 INT150222 Positive_regulation of Gene_expression of TNFSF13B 12 0.11 7.49 2.43
132 INT251734 Localization of CD70 1 0.69 3.93 2.42
133 INT95136 Binding of FASLG 6 0.33 8.01 2.41
134 INT81989 Positive_regulation of Tnfsf11 11 0.54 7.57 2.4
135 INT144490 Regulation of Gene_expression of Tnfsf11 14 0.58 14.09 2.39
136 INT93532 Regulation of Tnfsf11 14 0.42 10.75 2.39
137 INT59287 Positive_regulation of Eda 5 0.40 1.25 2.36
138 INT137960 Positive_regulation of FASLG 8 0.67 6.5 2.34
139 INT133766 Negative_regulation of Fasl 11 0.56 11.28 2.27
140 INT34796 Positive_regulation of TNFSF14 7 0.67 4.16 2.26
141 INT93395 Transcription of Faslg 6 0.51 5.64 2.26
142 INT66804 Negative_regulation of Negative_regulation of Tnf 4 0.56 2.79 2.26
143 INT74241 Positive_regulation of Gene_expression of EDA 3 0.49 4.93 2.24
144 INT109970 Negative_regulation of Casp8 5 0.52 9.34 2.19
145 INT114898 Regulation of Transcription of TNF 4 0.35 2.69 2.18
146 INT201652 Positive_regulation of Tnfsf10 26 0.68 26.79 2.14
147 INT116194 Gene_expression of Casp8 14 0.75 14.61 2.13
148 INT104931 Binding of TNFSF10 15 0.36 17.44 2.07
149 INT133607 Regulation of Fadd 1 0.60 0.41 2.04
150 INT43044 Gene_expression of Eda 3 0.75 0.69 2
151 INT161121 Binding of Erap1 2 0.48 1.99 1.99
152 INT122649 Positive_regulation of Regulation of Tnf 2 0.49 2.78 1.96
153 INT133605 Positive_regulation of Negative_regulation of Fadd 1 0.46 0.28 1.96
154 INT142461 Positive_regulation of Positive_regulation of Stat1 7 0.54 5.06 1.94
155 INT139174 Positive_regulation of Fadd 1 0.59 0.83 1.94
156 INT88016 Negative_regulation of Gene_expression of Faslg 5 0.54 2.18 1.93
157 INT102147 Negative_regulation of Faslg 5 0.19 4.56 1.92
158 INT139185 Phosphorylation of Fadd 1 0.69 0.59 1.92
159 INT20227 Regulation of Lta 11 0.35 6.16 1.91
160 INT70054 Transcription of LTA 3 0.62 3.05 1.91
161 INT125869 Regulation of Gene_expression of TNFSF10 5 0.38 8.77 1.9
162 INT133609 Negative_regulation of Positive_regulation of Fadd 2 0.46 0.24 1.9
163 INT226894 Negative_regulation of Tnfsf10 14 0.57 16.64 1.87
164 INT111675 Regulation of TNFSF14 3 0.26 3.41 1.85
165 INT130866 Positive_regulation of Gene_expression of TNFSF11 25 0.69 7.11 1.82
166 INT130775 Regulation of FASLG 4 0.30 5.8 1.82
167 INT125865 Regulation of TNFSF10 12 0.44 15.75 1.81
168 INT13544 Localization of LTA 9 0.78 6.34 1.8
169 INT150223 Regulation of Gene_expression of TNFSF13B 2 0.21 3.44 1.8
170 INT77801 Negative_regulation of Binding of Tnf 5 0.42 3.93 1.77
171 INT130771 Transcription of TNFSF10 3 0.51 3.4 1.74
172 INT119837 Positive_regulation of Gene_expression of STAT1 6 0.49 3.66 1.73
173 INT138917 Positive_regulation of Gene_expression of Stat1 63 0.69 36.76 1.71
174 INT203174 Regulation of Gene_expression of LTA 5 0.15 2.64 1.7
175 INT139177 Regulation of Fadd 1 0.60 0.78 1.69
176 INT224643 Positive_regulation of Gene_expression of Tnfsf10 13 0.46 11.1 1.67
177 INT62046 Negative_regulation of Lta 8 0.43 4.42 1.67
178 INT159957 Positive_regulation of Phosphorylation of Tnf 3 0.49 2.63 1.65
179 INT306930 Gene_expression of Tnfsf12 1 0.31 21.25 1.65
180 INT107299 Transcription of Fasl 6 0.68 5 1.64
181 INT15544 Regulation of CASP8 6 0.41 5.83 1.63
182 INT26393 Localization of Eda 4 0.60 0.18 1.63
183 INT182643 Binding of TNFSF11 15 0.35 13.12 1.61
184 INT156229 Binding of Tnfsf14 5 0.23 4.69 1.6
185 INT186309 Binding of Stat1 18 0.48 5.31 1.58
186 INT51840 Positive_regulation of Localization of CD40LG 8 0.69 9.59 1.58
187 INT140089 Positive_regulation of Stat1 5 0.68 3.42 1.58
188 INT93394 Positive_regulation of Transcription of Faslg 1 0.24 3.57 1.57
189 INT161379 Localization of Fasl 8 0.67 11.05 1.56
190 INT183791 Positive_regulation of Phosphorylation of TNF 6 0.49 4.72 1.56
191 INT134148 Gene_expression of FADD 4 0.66 3.35 1.54
192 INT28679 Gene_expression of Tnfsf13b 5 0.60 2.75 1.53
193 INT137819 Binding of Faslg 3 0.09 1.78 1.51
194 INT171329 Binding of TNFSF12 1 0.04 3.87 1.51
195 INT61967 Positive_regulation of Negative_regulation of Tnf 3 0.50 2.46 1.49
196 INT186064 Phosphorylation of STAT1 19 0.59 7.14 1.48
197 INT49992 Positive_regulation of Lta 5 0.47 2.8 1.47
198 INT162057 Negative_regulation of TNFSF11 14 0.58 9.78 1.46
199 INT88015 Positive_regulation of Faslg 5 0.65 5.73 1.44
200 INT49402 Positive_regulation of EDA 6 0.61 4.23 1.43
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