GO:0005166

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Name neurotrophin p75 receptor binding
Categary Function
Go Slim No
Go Link GO:0005166
Unique Molecular Interactions 82
Total Molecular Interactions 150
Total Single Events 679
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for neurotrophin p75 receptor binding. They are ordered first by their pain relevance and then by number of times they were reported for neurotrophin p75 receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26
2 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23
3 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92
4 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
5 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84
6 INT83418 Binding of OPRL1 and Ntrk1 1 0.02 0 1.91
7 INT108385 Binding of Crygs and Ntrk1 1 0.01 0 1.67
8 INT83416 Binding of OPRK1 and Ntrk1 1 0.02 0 1.45
9 INT82025 Negative_regulation of Binding of Ntrk1 and Ngf 1 0.47 0.64 1.37
10 INT83197 Binding of Ntrk1 and Gdnf 1 0.01 1.05 1.36
11 INT242623 Binding of Ntf3 and Ntrk3 5 0.22 1.31 1.29
12 INT351373 Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
13 INT351378 Gene_expression of Ngf Positive_regulation of Ntrk1 1 0.35 0.41 1.18
14 INT351377 Gene_expression of Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
15 INT256041 Binding of Ngfr and Ntrk1 3 0.14 0.9 1.13
16 INT93614 Ngf Positive_regulation of Ntrk1 2 0.52 0.85 1.05
17 INT83415 Binding of Oprm1 and Ntrk1 1 0.01 0 0.96
18 INT297463 Binding of Ntrk1 and Ngf 1 0.10 0.78 0.87
19 INT298295 Runx1 Negative_regulation of Gene_expression of Ntrk1 2 0.38 0.45 0.86
20 INT256045 Binding of BDNF and Ntrk1 3 0.34 0.65 0.83
21 INT78714 Ntrk1 Positive_regulation of Ngf 2 0.50 0.63 0.78
22 INT213726 Binding of Ngfr and Ntrk1 1 0.14 0.96 0.72
23 INT351376 Mir470 Negative_regulation of Ntrk1 1 0.01 1.54 0.7
24 INT221847 Binding of Calca and Ntrk1 1 0.03 0.9 0.65
25 INT79747 Ntf3 Regulation of Positive_regulation of Ntrk1 1 0.35 0 0.6
26 INT98035 Binding of Ntrk1 and Trpv1 1 0.54 0.41 0.57
27 INT242602 Binding of Ntf3 and Ntrk1 1 0.10 0.14 0.57
28 INT245553 Runx1 Positive_regulation of Gene_expression of Ntrk1 2 0.45 1.41 0.52
29 INT242631 Binding of Gfra2 and Ntrk1 1 0.01 0 0.52
30 INT256040 Ngf Regulation of Gene_expression of Ntrk1 1 0.36 0.73 0.5
31 INT242634 Binding of Gfra1 and Ntrk1 1 0.02 0 0.46
32 INT242596 Binding of Ntrk1 and Ret 1 0.12 0 0.46
33 INT256042 Negative_regulation of Musk Negative_regulation of Ntrk1 1 0.08 0.48 0.44
34 INT298284 Runx3 Negative_regulation of Gene_expression of Ntrk1 1 0.26 0.39 0.43
35 INT298263 Pou4f1 Regulation of Gene_expression of Ntrk1 1 0.34 0.61 0.43
36 INT139654 Ntf3 Regulation of Gene_expression of Grin1 1 0.56 0.11 0.41
37 INT242607 Negative_regulation of Ntrk1 Positive_regulation of Ret 1 0.16 0 0.39
38 INT298266 Gene_expression of Runx1 Positive_regulation of Ntrk1 1 0.28 0.34 0.39
39 INT166247 Ngf Regulation of Ntrk1 1 0.05 0.09 0.38
40 INT73537 Ntf3 Positive_regulation of Ngfr 1 0.21 0.1 0.38
41 INT223470 Ret Regulation of Ntrk1 1 0.21 0 0.36
42 INT148241 Binding of Kit and Ntrk1 1 0.25 0.44 0.35
43 INT129022 Ngf Positive_regulation of Phosphorylation of Ntrk1 1 0.39 0.37 0.31
44 INT242622 Binding of Bdnf and Ntrk1 1 0.05 0.07 0.29
45 INT245554 Tbx15 Positive_regulation of Gene_expression of Ntrk1 1 0.02 0.65 0.29
46 INT118652 Positive_regulation of Bdnf Positive_regulation of Ntrk1 1 0.31 0.24 0.29
47 INT118654 Bdnf Positive_regulation of Ntrk1 1 0.43 0.24 0.28
48 INT166605 Binding of BDNF and Ntf3 1 0.16 0.46 0.28
49 INT56056 Binding of Ntf3 and Tfg 1 0.04 0.49 0.25
50 INT56058 Negative_regulation of Binding of Ntf3 and Tfg 1 0.05 0.5 0.25
51 INT213566 Binding of Bdnf and Ntf5 1 0.30 0 0.24
52 INT245567 Tbx15 Positive_regulation of Ntrk1 1 0.02 0.9 0.24
53 INT213544 Binding of Ntf4 and Ntf5 1 0.34 0 0.24
54 INT154594 Ntf5 Positive_regulation of Gene_expression of Kcna3 1 0.05 0.07 0.23
55 INT280473 Binding of Ntrk1 and Ntf4 1 0.00 0.13 0.2
56 INT223477 Binding of Ntrk1 and Ntrk3 2 0.16 0.3 0.19
57 INT298256 Runx1 Positive_regulation of Negative_regulation of Ntrk1 1 0.30 0.55 0.16
58 INT349861 Gfra1 Negative_regulation of Ntrk1 1 0.01 0.36 0.15
59 INT349852 Gfra2 Negative_regulation of Ntrk1 1 0.27 0.3 0.15
60 INT245566 Runx1 Negative_regulation of Ntrk1 1 0.39 0.65 0.15
61 INT349859 Gfra2 Negative_regulation of Ntrk1 1 0.02 0.3 0.15
62 INT349862 Gfra3 Negative_regulation of Ntrk1 1 0.02 0.3 0.15
63 INT201728 Ntrk1 Regulation of Transcription of App 1 0.03 0.39 0.15
64 INT349856 Gfra3 Negative_regulation of Ntrk1 1 0.23 0.3 0.15
65 INT349854 Gfra1 Negative_regulation of Ntrk1 1 0.12 0.36 0.15
66 INT223475 Binding of Ntrk1 and Ntrk2 2 0.22 0.25 0.14
67 INT151925 Bdnf Negative_regulation of Ntrk1 1 0.10 0 0.14
68 INT321181 Binding of Ntrk2 and Ntf5 1 0.09 0.08 0.14
69 INT153620 Binding of Ntrk1 and WNK1 1 0.02 0.85 0.12
70 INT280893 Gene_expression of Runx1 Positive_regulation of Gene_expression of Ntrk1 1 0.33 0.44 0.1
71 INT280492 Ntrk1 Regulation of Protein_catabolism of BDNF 1 0.03 0.14 0.1
72 INT122927 Ntrk1 Positive_regulation of SPTLC1 1 0.00 0.65 0.09
73 INT280894 Runx1 Positive_regulation of Transcription of Ntrk1 1 0.38 0.36 0.07
74 INT121225 Positive_regulation of Ngf Positive_regulation of Ntrk1 2 0.49 0 0
75 INT321180 Ntrk2 Regulation of Ntrk1 1 0.16 0 0
76 INT278264 Gene_expression of Ntf3 Positive_regulation of Smcp 1 0.02 0.32 0
77 INT200065 Binding of MAGED1 and Ntf3 1 0.32 0.23 0
78 INT124074 Binding of Ntrk1 and Ugt1a10 1 0.06 0 0
79 INT325947 Ezr Regulation of Zfp369 1 0.00 0.84 0
80 INT200054 Binding of Ntf3 and Mageh1 1 0.24 0.22 0
81 INT223478 Binding of Ntrk1 and Dok5 1 0.18 0.17 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for neurotrophin p75 receptor binding. They are ordered first by their pain relevance and then by number of times they were reported in neurotrophin p75 receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28
2 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83
3 INT56769 Gene_expression of Ntrk1 36 0.77 15.79 20.75
4 INT50972 Negative_regulation of Ntrk1 39 0.51 32.22 17.29
5 INT97871 Gene_expression of Ntf3 47 0.78 25.9 15.94
6 INT108384 Binding of Ntrk1 28 0.39 10.73 9.09
7 INT97870 Positive_regulation of Gene_expression of Ntf3 19 0.70 9.56 7.8
8 INT50973 Negative_regulation of Gene_expression of Ntrk1 22 0.56 11.12 7.38
9 INT129020 Phosphorylation of Ntrk1 17 0.80 5.97 6.37
10 INT79737 Positive_regulation of Ntrk1 12 0.49 3.98 6.24
11 INT126505 Positive_regulation of Ntf3 26 0.70 9.17 4.92
12 INT78981 Regulation of Ntrk1 6 0.44 3.89 4.52
13 INT81750 Regulation of Ntrk1 13 0.52 6.03 4.37
14 INT79736 Negative_regulation of Ntrk1 11 0.57 2.31 4.14
15 INT56768 Positive_regulation of Gene_expression of Ntrk1 5 0.67 3.91 3.83
16 INT83411 Binding of Ntrk1 6 0.19 3.7 3.74
17 INT156189 Positive_regulation of Gene_expression of Ntrk1 11 0.49 2.81 2.89
18 INT62610 Phosphorylation of Ntrk1 5 0.56 1.64 2.68
19 INT139648 Localization of Ntf3 7 0.66 3.73 2.22
20 INT56054 Negative_regulation of Ntf3 7 0.59 2.75 1.86
21 INT107477 Positive_regulation of Phosphorylation of Ntrk1 3 0.30 0.88 1.86
22 INT223447 Regulation of Gene_expression of Ntrk1 7 0.34 1.29 1.82
23 INT105200 Binding of Ntf3 6 0.31 2.46 1.67
24 INT167145 Regulation of Gene_expression of Ntf3 6 0.54 3.4 1.64
25 INT126504 Regulation of Ntf3 5 0.39 4.3 1.54
26 INT109586 Negative_regulation of Ntf5 4 0.43 1.99 1.48
27 INT129017 Negative_regulation of Phosphorylation of Ntrk1 3 0.41 1.5 1.42
28 INT245532 Negative_regulation of Positive_regulation of Ntrk1 2 0.34 1.56 1.34
29 INT93612 Transcription of Ntrk1 2 0.52 1.31 1.26
30 INT256036 Positive_regulation of Ntf5 2 0.04 1.96 1.16
31 INT93610 Negative_regulation of Gene_expression of Ntrk1 2 0.41 0.84 1.15
32 INT124069 Localization of Ntrk1 9 0.59 3.32 1.13
33 INT201635 Positive_regulation of Positive_regulation of Ntrk1 3 0.40 1.15 0.85
34 INT93609 Positive_regulation of Transcription of Ntrk1 1 0.45 0.86 0.69
35 INT62608 Negative_regulation of Phosphorylation of Ntrk1 1 0.40 0.24 0.69
36 INT93613 Regulation of Gene_expression of Ntrk1 1 0.60 0.8 0.59
37 INT118730 Regulation of Transcription of Ntrk1 1 0.43 0.45 0.57
38 INT256034 Localization of Ntf5 1 0.05 0.86 0.5
39 INT97723 Negative_regulation of Regulation of Ntrk1 1 0.37 0.52 0.45
40 INT166599 Negative_regulation of Gene_expression of Ntf3 2 0.47 2.72 0.43
41 INT297454 Negative_regulation of Negative_regulation of Ntrk1 1 0.09 0.23 0.41
42 INT242553 Positive_regulation of Negative_regulation of Ntrk1 1 0.21 0 0.39
43 INT166598 Phosphorylation of Ntf3 2 0.56 0.55 0.36
44 INT148814 Localization of Ntrk1 1 0.78 0.16 0.34
45 INT245522 Positive_regulation of Localization of Ntf3 1 0.29 0.88 0.34
46 INT244625 Negative_regulation of Localization of Ntrk1 1 0.04 0.56 0.28
47 INT256037 Binding of Ntf5 1 0.04 0.22 0.28
48 INT280460 Positive_regulation of Localization of Ntrk1 2 0.11 0.32 0.21
49 INT167146 Transcription of Ntf3 2 0.69 0.52 0.21
50 INT242558 Transcription of Ntrk1 2 0.37 0.66 0.17
51 INT126506 Positive_regulation of Positive_regulation of Ntf3 2 0.47 0.32 0.11
52 INT242544 Positive_regulation of Transcription of Ntrk1 1 0.29 0.3 0.1
53 INT167144 Regulation of Positive_regulation of Ntf3 2 0.45 0.06 0
54 INT155405 Negative_regulation of Positive_regulation of Ntrk1 1 0.09 0.15 0
55 INT325929 Gene_expression of Zfp369 1 0.01 1.8 0
56 INT351372 Regulation of Localization of Ntrk1 1 0.34 0.92 0
57 INT325938 Positive_regulation of Zfp369 1 0.00 0.08 0
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