GO:0005174

From wiki-pain
Jump to: navigation, search
Name CD40 receptor binding
Categary Function
Go Slim No
Go Link GO:0005174
Unique Molecular Interactions 58
Total Molecular Interactions 144
Total Single Events 975
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for CD40 receptor binding. They are ordered first by their pain relevance and then by number of times they were reported for CD40 receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62
2 INT140935 Binding of Cd40lg and Cd40 1 0.30 6.34 5.61
3 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01
4 INT83425 Binding of CD40LG and IGHG3 11 0.21 4.56 2.09
5 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
6 INT131853 CD40 Negative_regulation of Gene_expression of CD40LG 1 0.09 1.54 1.05
7 INT140936 Binding of Cd40lg and Ean5 1 0.07 1.03 0.98
8 INT160413 Tat Positive_regulation of Gene_expression of Cd40lg 1 0.50 0.98 0.86
9 INT125234 Positive_regulation of Binding of BCR and CD40LG 1 0.31 0.76 0.86
10 INT125233 Binding of BCR and CD40LG 1 0.23 0.75 0.85
11 INT236364 CD40LG Positive_regulation of Gene_expression of IL6 1 0.25 1.37 0.72
12 INT83424 Binding of CD40LG and ADIPOQ 2 0.13 1 0.59
13 INT83426 ADIPOQ Negative_regulation of Binding of CD40LG 2 0.21 1 0.59
14 INT191503 CD40LG Regulation of Gene_expression of F3 1 0.01 0.99 0.27
15 INT188699 Binding of Cd40lg and Eae1 1 0.05 1.51 0.24
16 INT350016 Binding of CD40LG and ARID1B 1 0.01 3.26 0.21
17 INT322733 CD40LG Positive_regulation of Gene_expression of CD40 1 0.08 0.62 0.18
18 INT322734 Binding of CD40LG and Positive_regulation of CD40 1 0.07 0.62 0.18
19 INT111802 Binding of CD40LG and TFPI 1 0.14 0.62 0.16
20 INT85445 NUBPL Negative_regulation of Gene_expression of CD40LG 1 0.01 0.31 0.16
21 INT194576 Binding of ACLY and CD40LG 1 0.07 0.07 0.14
22 INT298476 CD40LG Positive_regulation of HLA-DRB1 1 0.01 0.33 0.12
23 INT298471 CD40LG Positive_regulation of CD80 1 0.04 0.33 0.12
24 INT240770 Binding of CD40LG and F13A1 1 0.02 1.4 0.09
25 INT251569 Binding of Ripk1 and Traf2 1 0.12 0.67 0.08
26 INT202505 Binding of Cd40lg and Positive_regulation of Positive_regulation of Nfasc 1 0.09 0.45 0.08
27 INT277807 CD40LG Regulation of CD40 1 0.21 0.17 0.08
28 INT331561 Binding of Cd4 and Cd40lg 1 0.28 0.06 0.06
29 INT328667 Binding of CD40LG and CSF2 1 0.16 0.59 0.05
30 INT234380 Negative_regulation of Binding of CD40 and CD40LG 1 0.16 1.4 0.04
31 INT190095 Negative_regulation of Binding of Hivep3 and Traf2 1 0.15 0.08 0.04
32 INT190096 Binding of Hivep3 and Traf2 1 0.17 0.08 0.04
33 INT227774 Negative_regulation of Binding of Cd40 and Cd40lg 1 0.31 0.29 0.03
34 INT348526 Binding of TRAF2 and EDAR 1 0.15 0.52 0.03
35 INT348538 Binding of TRAF2 and EDARADD 1 0.06 0.53 0.03
36 INT292553 Binding of TRAF2 and TRADD 1 0.09 0.1 0
37 INT292560 Binding of TNFRSF1A and TRAF2 1 0.08 0.09 0
38 INT344266 Binding of APOH and CD40LG 1 0.04 0.31 0
39 INT252331 Binding of Cd40lg and Mthfd1 1 0.03 0.1 0
40 INT348521 TRAF2 Positive_regulation of MAP3K1 1 0.03 0.46 0
41 INT277809 Binding of CD4 and CD40LG 1 0.15 0 0
42 INT286653 Binding of CD40LG and OLR1 1 0.08 0.41 0
43 INT101943 Binding of CD40LG and HSD11B1 1 0.08 0.23 0
44 INT308702 Binding of AQP4 and CD40LG 1 0.10 0 0
45 INT348528 TRAF2 Positive_regulation of Positive_regulation of CASP8 1 0.02 0.44 0
46 INT336574 Binding of CD40LG and HCRTR1 1 0.05 0.1 0
47 INT83446 CD40LG Positive_regulation of Localization of CCL2 1 0.00 0.17 0
48 INT252334 Positive_regulation of Binding of Cd40 and Cd40lg 1 0.11 0.1 0
49 INT194926 Binding of CD40LG and Positive_regulation of BCR 1 0.04 0.39 0
50 INT222870 Traf2 Positive_regulation of Chuk 1 0.03 0.37 0
51 INT194927 Binding of CD40LG and Positive_regulation of CD79B 1 0.01 0.4 0
52 INT147062 LAMC2 Negative_regulation of CD40LG 1 0.47 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for CD40 receptor binding. They are ordered first by their pain relevance and then by number of times they were reported in CD40 receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23
2 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46
3 INT24816 Binding of CD40LG 68 0.47 45.48 11.56
4 INT85966 Gene_expression of Cd40lg 50 0.73 30.9 9.11
5 INT1124 Negative_regulation of CD40LG 53 0.57 36.26 7
6 INT83451 Positive_regulation of Gene_expression of CD40LG 26 0.60 22.81 6.25
7 INT45753 Localization of CD40LG 45 0.79 32.31 5.28
8 INT85965 Binding of Cd40lg 26 0.45 16.76 4.52
9 INT5148 Regulation of CD40LG 25 0.44 21.58 4.05
10 INT140933 Binding of Cd40lg 1 0.38 4.2 3.6
11 INT140931 Gene_expression of Cd40lg 5 0.61 5.2 3.33
12 INT85971 Positive_regulation of Gene_expression of Cd40lg 14 0.66 7.61 3.29
13 INT125237 Negative_regulation of Gene_expression of CD40LG 16 0.54 9.9 3.27
14 INT85970 Positive_regulation of Cd40lg 21 0.53 8.51 3.16
15 INT51840 Positive_regulation of Localization of CD40LG 8 0.69 9.59 1.58
16 INT190067 Binding of Traf2 5 0.20 3.28 1.27
17 INT188667 Localization of Cd40lg 5 0.57 3.29 1.07
18 INT188664 Negative_regulation of Cd40lg 7 0.33 3.99 1.04
19 INT140928 Negative_regulation of Gene_expression of Cd40lg 1 0.46 1.09 1.01
20 INT177387 Positive_regulation of TRAF2 3 0.26 1.44 0.84
21 INT160406 Transcription of Cd40lg 2 0.52 1.52 0.83
22 INT250281 Positive_regulation of Positive_regulation of CD40LG 3 0.23 3.19 0.73
23 INT85969 Regulation of Gene_expression of Cd40lg 2 0.43 1.96 0.69
24 INT285262 Regulation of Cd40lg 3 0.34 1.48 0.66
25 INT178201 Negative_regulation of Binding of Cd40lg 2 0.33 2.92 0.64
26 INT112665 Gene_expression of TRAF2 3 0.29 3.97 0.61
27 INT130373 Regulation of Gene_expression of CD40LG 3 0.60 1.87 0.59
28 INT154745 Protein_catabolism of Traf2 1 0.86 1.04 0.59
29 INT154750 Positive_regulation of Protein_catabolism of Traf2 1 0.60 1.05 0.59
30 INT294555 Negative_regulation of Traf2 1 0.06 1.24 0.58
31 INT83435 Negative_regulation of Binding of CD40LG 2 0.39 0.96 0.55
32 INT236370 Positive_regulation of Phosphorylation of CD40LG 1 0.37 0.59 0.55
33 INT190074 Positive_regulation of Traf2 1 0.19 0.37 0.52
34 INT83436 Positive_regulation of Binding of CD40LG 3 0.33 0.85 0.49
35 INT151274 Negative_regulation of Gene_expression of Cd40lg 3 0.32 2.16 0.3
36 INT153836 Phosphorylation of CD40LG 2 0.79 0.47 0.28
37 INT285263 Positive_regulation of Negative_regulation of Cd40lg 1 0.26 0.34 0.19
38 INT76125 Transcription of CD40LG 5 0.55 2.66 0.18
39 INT219192 Positive_regulation of Regulation of CD40LG 2 0.43 2.9 0.17
40 INT252702 Binding of TRAF2 3 0.23 2.21 0.16
41 INT154744 Regulation of Protein_catabolism of Traf2 1 0.39 0.18 0.16
42 INT332303 Localization of Cd40lg 1 0.00 0.26 0.14
43 INT285264 Regulation of Localization of Cd40lg 1 0.25 0.42 0.13
44 INT251559 Binding of Traf2 1 0.23 1.68 0.13
45 INT219164 Regulation of Positive_regulation of CD40LG 1 0.04 1.51 0.13
46 INT257930 Regulation of Binding of Cd40lg 1 0.13 1.14 0.12
47 INT240780 Negative_regulation of Localization of CD40LG 2 0.24 0.72 0.1
48 INT252306 Positive_regulation of Binding of Cd40lg 1 0.22 0.55 0.1
49 INT251560 Positive_regulation of Traf2 1 0.13 0.47 0.09
50 INT285261 Regulation of Positive_regulation of Cd40lg 1 0.15 0.11 0.05
51 INT222849 Gene_expression of Traf2 1 0.12 0.38 0
52 INT252712 Phosphorylation of TRAF2 1 0.28 1.38 0
53 INT348474 Regulation of Gene_expression of TRAF2 1 0.23 0.41 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox