GO:0005178

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Name integrin binding
Categary Function
Go Slim No
Go Link GO:0005178
Unique Molecular Interactions 1274
Total Molecular Interactions 1848
Total Single Events 18209
Pain Genes Associated 114

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for integrin binding. They are ordered first by their pain relevance and then by number of times they were reported for integrin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
2 INT215943 Binding of Mmp14 and Timp2 1 0.21 1.59 3.33
3 INT130085 Crp Positive_regulation of Gene_expression of Vcam1 1 0.23 4.34 2.84
4 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81
5 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
6 INT281381 FSCN1 Positive_regulation of Gene_expression of Gfap 1 0.06 1.13 1.98
7 INT137917 Oprm1 Positive_regulation of Kdr 1 0.43 0 1.98
8 INT113550 Binding of FN1 and VTN 6 0.30 5.24 1.91
9 INT134686 FSCN1 Positive_regulation of Gfap 1 0.00 0.71 1.89
10 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83
11 INT169468 Binding of Egfr and Spink3 1 0.37 3.73 1.83
12 INT192161 Mmp14 Positive_regulation of Mmp2 2 0.19 1.23 1.81
13 INT100771 Binding of Itga1 and Vcam1 3 0.11 3.91 1.79
14 INT6407 Binding of Lama5 and Oprm1 1 0.02 0.08 1.72
15 INT24817 Binding of POMC and VTN 8 0.42 0.39 1.71
16 INT18786 Binding of Adra2a and Nisch 2 0.19 0 1.7
17 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
18 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
19 INT326509 Binding of ACE and VWF 1 0.05 2.07 1.59
20 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
21 INT130839 Gfap Positive_regulation of S100B 1 0.51 1.9 1.56
22 INT130838 Gfap Positive_regulation of Aqp4 1 0.51 1.9 1.56
23 INT158762 Binding of Vwf and Mthfr 1 0.05 1.85 1.37
24 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31
25 INT131184 PTGER2 Positive_regulation of Gene_expression of IGF1 1 0.63 2.47 1.29
26 INT112961 NGF Positive_regulation of ICAM1 1 0.40 0.96 1.28
27 INT177232 ICAM1 Regulation of Gene_expression of Vcam1 1 0.03 5.52 1.28
28 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
29 INT151657 Vcam1 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
30 INT151658 F3 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
31 INT334129 Acsm3 Positive_regulation of Gene_expression of Icam1 1 0.22 2.89 1.22
32 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
33 INT134487 Positive_regulation of TGFBI Positive_regulation of Ltp 1 0.03 1.19 1.11
34 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
35 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07
36 INT150794 ZNF398 Positive_regulation of Localization of THBS1 1 0.09 1.02 1.07
37 INT139230 Icam1 Negative_regulation of Cmklr1 1 0.19 1.13 1.07
38 INT139227 Icam1 Negative_regulation of Timp1 1 0.37 1.13 1.06
39 INT139225 Calca Negative_regulation of Icam1 1 0.44 1.13 1.06
40 INT150789 THBS3 Negative_regulation of THBS1 1 0.18 1.01 1.06
41 INT139226 Icam1 Negative_regulation of Calca 1 0.44 1.12 1.05
42 INT106345 Igf1 Regulation of Localization of Acot1 1 0.06 0 1.02
43 INT12141 Igf1 Negative_regulation of Chat 1 0.32 0.63 1
44 INT140653 IGF1 Negative_regulation of Protein_catabolism of PARP1 1 0.32 0.63 0.98
45 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
46 INT137920 Binding of Kdr and Oprm1 1 0.23 0 0.97
47 INT187111 TIMP2 Regulation of MMP9 1 0.23 1.47 0.97
48 INT289173 PYCARD Regulation of MFGE8 1 0.05 0 0.96
49 INT253836 Cck Regulation of DST 1 0.03 0.42 0.95
50 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
51 INT106707 POMC Regulation of Binding of LAMB2 1 0.03 0.7 0.94
52 INT161455 Mmp7 Positive_regulation of Egfr 1 0.03 0.19 0.92
53 INT289461 IRF6 Positive_regulation of ICAM1 1 0.08 0.61 0.91
54 INT149386 Binding of Lyn and TRPV4 1 0.40 1.14 0.91
55 INT169469 Binding of Egfr and Tgfa 1 0.19 1.87 0.91
56 INT260842 Binding of NRP2 and Kdr 1 0.00 2.28 0.85
57 INT129881 Binding of Calr and Cbll1 1 0.00 0.58 0.84
58 INT94665 Nisch Negative_regulation of Maoa 1 0.07 0 0.83
59 INT282129 Il10 Positive_regulation of Icam1 1 0.56 3.12 0.82
60 INT117341 ADAM17 Positive_regulation of EGFR 1 0.16 3.56 0.82
61 INT119772 Binding of Cd53 and Gfap 1 0.04 1.01 0.81
62 INT322397 Egfr Positive_regulation of Adarb1 1 0.00 0.08 0.8
63 INT63544 Adra2a Regulation of Nisch 1 0.18 0 0.79
64 INT102162 Binding of TNF and Adam17 1 0.14 0.88 0.78
65 INT182814 Binding of ICAM1 and PECAM1 2 0.02 3.32 0.77
66 INT181615 SRC Positive_regulation of IRS1 1 0.01 0.98 0.77
67 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
68 INT102159 Binding of Adam17 and Mmp2 1 0.18 0.87 0.77
69 INT149192 TNF Positive_regulation of Gene_expression of VCAM1 3 0.57 1.4 0.76
70 INT173112 IL1B Positive_regulation of Gene_expression of VCAM1 2 0.43 1.34 0.76
71 INT113549 Binding of VTN and alphavbeta3 integrin receptor 1 0.09 2.05 0.76
72 INT113472 TNF Positive_regulation of Localization of MMP14 1 0.47 0.45 0.75
73 INT133675 NPY6R Negative_regulation of SRC 1 0.17 0.75 0.74
74 INT316673 Binding of CALR and LRP1 1 0.39 1.89 0.74
75 INT317585 Binding of Lbp and Ppap2b 1 0.03 0.78 0.72
76 INT317586 Binding of SCLY and Ppap2b 1 0.00 0.78 0.72
77 INT180775 Binding of Gdnf and Gfra1 1 0.06 0.52 0.71
78 INT196526 Binding of TIMP1 and TIMP2 1 0.45 1.49 0.71
79 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69
80 INT34772 GH1 Regulation of IGF1 2 0.32 0.95 0.69
81 INT104301 Adam17 Regulation of Negative_regulation of Sell 1 0.39 0.58 0.69
82 INT282665 Binding of Gfap and Ticam1 1 0.01 0 0.69
83 INT73823 TFF2 Positive_regulation of Gene_expression of VCAM1 1 0.04 0.59 0.69
84 INT224678 Binding of Mmp14 and Mmp23 1 0.00 0.85 0.69
85 INT282664 Binding of Aif1 and Gfap 1 0.06 0 0.69
86 INT79937 TAC1 Positive_regulation of Gene_expression of VCAM1 1 0.20 0.15 0.68
87 INT70998 IL1B Regulation of Gene_expression of Icam1 1 0.44 0.95 0.67
88 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66
89 INT334133 Acsm3 Positive_regulation of Icam1 1 0.23 1.61 0.66
90 INT334127 Acsm3 Positive_regulation of Vcam1 1 0.24 1.61 0.66
91 INT224683 Mmp14 Positive_regulation of Binding of Mmp9 1 0.01 0.81 0.65
92 INT45369 IGF1 Regulation of GH1 1 0.04 1.12 0.65
93 INT224693 Timp2 Positive_regulation of Binding of Mmp9 1 0.01 0.81 0.65
94 INT66603 TFF2 Positive_regulation of Gene_expression of ICAM1 1 0.02 0 0.64
95 INT224684 Binding of Mmp14 and Mmp9 1 0.01 0.81 0.64
96 INT113473 RETNLB Positive_regulation of MMP14 1 0.01 0.37 0.64
97 INT329297 Binding of Cd226 and Aff3 1 0.18 1.54 0.64
98 INT318981 Binding of CALR and GOPC 1 0.03 0.77 0.64
99 INT346141 ADM Positive_regulation of Gene_expression of ICAM1 1 0.19 1.75 0.63
100 INT66601 WDR87 Positive_regulation of Gene_expression of ICAM1 1 0.00 0 0.63
101 INT66604 SARDH Positive_regulation of Gene_expression of ICAM1 1 0.01 0 0.63
102 INT176475 IL1B Positive_regulation of Gene_expression of ICAM1 1 0.02 0.56 0.62
103 INT182815 Binding of CD63 and ICAM1 1 0.00 1.63 0.61
104 INT92996 Binding of VCAM1 and GORASP1 1 0.39 0.33 0.6
105 INT89012 DST Positive_regulation of Insr 1 0.01 0.86 0.59
106 INT65285 TGFBI Negative_regulation of Pc 1 0.20 0.79 0.59
107 INT261372 Gsk3b Regulation of Gene_expression of Ifi205 1 0.00 0.24 0.58
108 INT261828 Igf1 Regulation of Localization of Trpv2 1 0.02 1.04 0.58
109 INT144071 TRPV1 Positive_regulation of Gene_expression of MMP14 1 0.21 0.5 0.58
110 INT156668 Gh Positive_regulation of Igf1 5 0.22 2.07 0.57
111 INT277828 Negative_regulation of Binding of ICAM1 and ITGAL 2 0.22 1.27 0.57
112 INT317639 Igf1 Regulation of Creb1 1 0.23 0.16 0.57
113 INT342619 Mmp2 Negative_regulation of Timp2 1 0.42 1.48 0.57
114 INT92999 Binding of CD40 and VCAM1 1 0.39 0.33 0.57
115 INT192291 OR5A1 Positive_regulation of Gene_expression of IGF1 1 0.02 0.93 0.57
116 INT342621 VEGFA Negative_regulation of Timp2 1 0.09 1.53 0.57
117 INT156667 Gh Positive_regulation of Gene_expression of Igf1 6 0.28 0.88 0.56
118 INT294708 CRP Positive_regulation of Gene_expression of VCAM1 2 0.31 1.92 0.56
119 INT66600 TFF2 Regulation of Positive_regulation of ICAM1 1 0.01 0 0.56
120 INT227911 Binding of VTN and MMRN1 1 0.01 1.16 0.56
121 INT150291 Grk1 Positive_regulation of Gene_expression of Igf1 1 0.16 0.98 0.55
122 INT106347 Igf1 Regulation of Chat 1 0.44 0 0.55
123 INT253835 Binding of DST and Fos 1 0.02 0 0.55
124 INT133049 TNF Positive_regulation of ICAM1 4 0.47 2.49 0.54
125 INT350169 Binding of DMD and MRI1 1 0.11 3.08 0.54
126 INT77508 ST13 Negative_regulation of Gene_expression of CD9 1 0.09 0.5 0.54
127 INT192162 Furin Positive_regulation of Mmp14 1 0.10 0.79 0.53
128 INT150795 ZNF398 Positive_regulation of Localization of TIMP2 1 0.06 0.51 0.53
129 INT150791 THBS1 Negative_regulation of TIMP2 1 0.17 0.5 0.52
130 INT192159 Mmp14 Regulation of Protein_catabolism of Col1a1 1 0.02 1.01 0.52
131 INT150796 ZNF398 Positive_regulation of THBS1 1 0.06 0.5 0.52
132 INT345308 Binding of ABCA1 and TIMP2 1 0.00 0.21 0.52
133 INT150798 THBS3 Negative_regulation of TIMP2 1 0.18 0.49 0.52
134 INT196521 Binding of MMP2 and TIMP2 1 0.30 0.68 0.52
135 INT150785 THBS1 Negative_regulation of MMP2 1 0.10 0.5 0.52
136 INT142882 IGF1 Positive_regulation of Gene_expression of TRPV1 1 0.06 0.57 0.52
137 INT333168 Tlx2 Negative_regulation of Gene_expression of Vcam1 1 0.14 0.71 0.51
138 INT187114 TIMP2 Negative_regulation of ABCA1 1 0.02 0.28 0.51
139 INT242614 Binding of Gdnf and Gfra1 1 0.03 0 0.51
140 INT137137 Binding of HIVEP1 and ICAM1 1 0.01 0.68 0.51
141 INT92997 Positive_regulation of SFTPA1 Positive_regulation of Binding of ICAM1 1 0.15 0.26 0.51
142 INT207466 LGALS3 Positive_regulation of Gene_expression of ADAMTS5 1 0.15 0.88 0.51
143 INT150799 ZNF398 Positive_regulation of TIMP2 1 0.09 0.49 0.51
144 INT333160 asa Negative_regulation of Gene_expression of Vcam1 1 0.19 0.71 0.5
145 INT187116 TIMP2 Negative_regulation of MMP9 1 0.36 1.37 0.5
146 INT313373 Cnr2 Positive_regulation of Gene_expression of Gfap 1 0.32 0.39 0.5
147 INT313371 Cnr1 Positive_regulation of Gene_expression of Gfap 1 0.35 0.39 0.5
148 INT56449 Aap Positive_regulation of Icam1 1 0.31 0.75 0.5
149 INT289464 Negative_regulation of IRF6 Positive_regulation of ICAM1 1 0.07 0.31 0.5
150 INT135586 CSF2 Regulation of ICAM1 1 0.13 1.3 0.49
151 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48
152 INT333151 asa Regulation of Gene_expression of Icam1 1 0.09 0.59 0.48
153 INT345306 Binding of MMP14 and TIMP2 1 0.04 0.21 0.48
154 INT108568 Calca Positive_regulation of Igf1 1 0.51 0.08 0.48
155 INT333156 Tlx2 Regulation of Gene_expression of Icam1 1 0.06 0.59 0.48
156 INT71178 Binding of ITGB2 and Icam1 1 0.45 1.2 0.47
157 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
158 INT333161 asa Negative_regulation of Positive_regulation of Vcam1 1 0.22 0.57 0.47
159 INT103929 Cps1 Negative_regulation of Gene_expression of Icam1 1 0.01 0.13 0.47
160 INT149894 Ihh Positive_regulation of Localization of Mmp14 1 0.04 2.06 0.47
161 INT261603 Il6 Regulation of Gene_expression of Vcam1 1 0.16 1.74 0.46
162 INT242628 Binding of Gfra1 and Ret 1 0.03 0 0.46
163 INT103931 Cps1 Negative_regulation of Icam1 1 0.01 0.07 0.46
164 INT146506 Regulation of Gfap Regulation of Gene_expression of Ccl2 1 0.08 0.7 0.46
165 INT117888 Gfap Regulation of Arc 1 0.05 0.37 0.46
166 INT116934 OPRK1 Positive_regulation of Positive_regulation of SRC 1 0.20 0.17 0.46
167 INT117890 Positive_regulation of Gfap Regulation of Glul 1 0.51 0.36 0.46
168 INT187099 Binding of Cd4 and Itga1 1 0.00 1.09 0.46
169 INT116933 SRC Positive_regulation of JUN 1 0.33 0.15 0.46
170 INT242634 Binding of Gfra1 and Ntrk1 1 0.02 0 0.46
171 INT116937 Positive_regulation of OPRK1 Positive_regulation of Positive_regulation of SRC 1 0.20 0.17 0.46
172 INT242615 Ret Positive_regulation of Gene_expression of Gfra1 1 0.04 0 0.46
173 INT117889 Gfap Regulation of Glul 1 0.30 0.36 0.46
174 INT117776 Binding of Ptk2 and Regulation of Phosphorylation of Ddr1 1 0.10 0.17 0.46
175 INT106001 Binding of PLAUR and VTN 2 0.23 1.5 0.45
176 INT65909 LAMB1 Positive_regulation of GANAB 1 0.00 0 0.45
177 INT345305 MMP14 Positive_regulation of MMP13 1 0.00 0.33 0.45
178 INT345304 MMP14 Positive_regulation of MMP2 1 0.08 0.2 0.45
179 INT262815 Gene_expression of Serpinf1 Negative_regulation of Gene_expression of Gfap 1 0.39 2.73 0.44
180 INT313377 Trib3 Regulation of Gene_expression of Gfap 1 0.01 0.37 0.44
181 INT264295 Binding of DMD and IGF1 1 0.07 1.38 0.44
182 INT113471 RETNLB Regulation of Localization of MMP14 1 0.01 0.24 0.43
183 INT332248 Ccl2 Positive_regulation of Ctgf 1 0.04 1.13 0.42
184 INT221085 GHRH Positive_regulation of Gene_expression of IGF1 2 0.56 1.47 0.41
185 INT244421 Binding of DST and Ctss 1 0.02 0.42 0.41
186 INT67633 Binding of DST and Gabrd 1 0.03 0 0.41
187 INT303655 Positive_regulation of Binding of IGF1 and SSTR1 1 0.16 2.19 0.41
188 INT120894 Binding of Gp1ba and Vwf 1 0.00 1.38 0.4
189 INT303650 Binding of IGF1 and SSTR1 1 0.12 2.17 0.4
190 INT171990 Binding of DMD and VDR 5 0.05 2.58 0.39
191 INT346148 Binding of ADM and VTN 1 0.15 0.93 0.39
192 INT321860 Timp1 Negative_regulation of Icam1 1 0.22 1.13 0.39
193 INT99304 Igf1 Positive_regulation of Gh1 1 0.44 0.39 0.39
194 INT257738 PIK3CA Regulation of Localization of ACTN4 1 0.16 1.03 0.39
195 INT346142 Positive_regulation of Binding of ADM and VTN 1 0.20 0.93 0.39
196 INT256321 INCENP Positive_regulation of Gene_expression of Vcam1 1 0.00 1.89 0.38
197 INT167946 Binding of SRC and Stat5b 1 0.28 0 0.38
198 INT113551 Binding of ITGA3 and VTN 1 0.02 1.03 0.38
199 INT288545 Gsk3b Negative_regulation of gr 1 0.25 0.38 0.38
200 INT130930 Egr1 Negative_regulation of Positive_regulation of Thbs1 1 0.58 0.64 0.38

Single Events

The table below shows the top 100 pain related interactions that have been reported for integrin binding. They are ordered first by their pain relevance and then by number of times they were reported in integrin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5842 Gene_expression of Gfap 372 0.78 153.71 127.71
2 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6
3 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71
4 INT5843 Positive_regulation of Gfap 184 0.70 108.2 70.21
5 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07
6 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71
7 INT6864 Positive_regulation of Gene_expression of Gfap 110 0.70 59.01 47.07
8 INT49105 Gene_expression of Vcam1 157 0.78 157.27 43.01
9 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28
10 INT51017 Positive_regulation of Icam1 113 0.70 81.16 35.55
11 INT14559 Gene_expression of Igf1 254 0.78 112 34.17
12 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51
13 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4
14 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25
15 INT20585 Gene_expression of Gfra1 39 0.77 26.94 26.69
16 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36
17 INT73670 Gene_expression of Vcam1 128 0.78 123.79 24.96
18 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04
19 INT49553 Regulation of Gene_expression of Gfap 42 0.62 17.04 23.65
20 INT6866 Regulation of Gfap 51 0.61 19.6 23.56
21 INT6868 Gene_expression of GFAP 136 0.78 84.65 22.7
22 INT48407 Positive_regulation of Gene_expression of Icam1 61 0.70 57.91 21.54
23 INT63340 Positive_regulation of Gene_expression of ICAM1 109 0.70 90.82 20.61
24 INT49103 Positive_regulation of Vcam1 71 0.69 59.52 19.85
25 INT48663 Negative_regulation of Gene_expression of Gfap 45 0.59 18.34 19.84
26 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9
27 INT9900 Positive_regulation of Vwf 80 0.69 51.85 18.13
28 INT62826 Negative_regulation of Gene_expression of ICAM1 75 0.58 46.39 17.72
29 INT62546 Positive_regulation of Gene_expression of Icam1 60 0.70 59.52 16.9
30 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47
31 INT99898 Gene_expression of Mmp14 37 0.56 28.54 16.39
32 INT56447 Positive_regulation of Icam1 64 0.64 64.14 16.16
33 INT11508 Positive_regulation of TGFBI 24 0.70 19.81 15.78
34 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51
35 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25
36 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06
37 INT79227 Negative_regulation of Gene_expression of Icam1 45 0.59 41.65 14.97
38 INT65263 Positive_regulation of Gene_expression of Igf1 61 0.69 25.69 14.49
39 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35
40 INT105156 Phosphorylation of Gfap 23 0.79 11.85 13.76
41 INT17539 Positive_regulation of Igf1 68 0.69 28.47 13.02
42 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32
43 INT92686 Gene_expression of Ctgf 51 0.77 34.4 11.93
44 INT73829 Positive_regulation of Gene_expression of VCAM1 41 0.61 35.96 11.92
45 INT65713 Localization of ICAM1 42 0.81 39.55 11.49
46 INT57187 Positive_regulation of Gfap 49 0.69 27.59 11.46
47 INT56448 Regulation of ICAM1 52 0.60 55.1 10.96
48 INT5840 Transcription of Gfap 26 0.71 18.18 10.41
49 INT49129 Positive_regulation of GFAP 35 0.69 28.78 10.38
50 INT101474 Positive_regulation of Gene_expression of Gfap 61 0.70 38.3 10.35
51 INT49555 Positive_regulation of Positive_regulation of Gfap 18 0.69 11.51 10.29
52 INT56450 Negative_regulation of Gene_expression of Icam1 33 0.52 27.21 10.15
53 INT134625 Gene_expression of Kdr 116 0.71 53.13 10.09
54 INT76573 Negative_regulation of Vcam1 26 0.58 24.36 9.84
55 INT6867 Positive_regulation of Gene_expression of GFAP 22 0.67 13.46 9.75
56 INT80549 Binding of ICAM1 53 0.47 42.76 9.72
57 INT11729 Regulation of IGF1 71 0.61 44.58 9.71
58 INT67101 Gene_expression of DST 47 0.54 25.92 9.59
59 INT63341 Negative_regulation of ICAM1 42 0.59 30.45 9.5
60 INT135372 Positive_regulation of Gsk3b 72 0.70 50.03 9.28
61 INT62829 Positive_regulation of VCAM1 39 0.70 38.42 9.15
62 INT9899 Gene_expression of Vwf 91 0.74 45.06 9.13
63 INT63338 Regulation of Gene_expression of ICAM1 42 0.62 28.26 9.06
64 INT100653 Negative_regulation of Gene_expression of Gfra1 6 0.58 8.26 8.95
65 INT34544 Gene_expression of L1cam 43 0.77 5.3 8.89
66 INT34777 Localization of IGF1 82 0.80 42.68 8.62
67 INT81444 Positive_regulation of Gene_expression of Vcam1 40 0.70 46.38 8.58
68 INT2225 Binding of Gfap 31 0.47 11.78 8.53
69 INT60034 Positive_regulation of VWF 40 0.68 30.42 8.15
70 INT3803 Negative_regulation of Igf1 45 0.58 15.95 7.98
71 INT62944 Regulation of Icam1 33 0.47 23.52 7.94
72 INT48404 Regulation of Gene_expression of Icam1 21 0.62 15.1 7.81
73 INT81399 Regulation of Vcam1 24 0.46 23.53 7.68
74 INT49104 Positive_regulation of Gene_expression of Vcam1 30 0.69 36.52 7.64
75 INT113705 Gene_expression of Egfr 228 0.78 149.05 7.59
76 INT82610 Positive_regulation of SRC 53 0.67 26.89 7.27
77 INT6861 Negative_regulation of Gfap 32 0.58 13.71 7.22
78 INT93664 Gene_expression of TIMP2 33 0.67 36.67 7.14
79 INT144945 Negative_regulation of Icam1 27 0.50 26.23 7.08
80 INT64671 Gene_expression of NISCH 10 0.69 2.19 6.9
81 INT142344 Transcription of Igf1 22 0.69 7.55 6.77
82 INT5839 Positive_regulation of Transcription of Gfap 10 0.49 11.61 6.74
83 INT38644 Positive_regulation of DST 30 0.53 12.48 6.59
84 INT117142 Gene_expression of Thbs1 58 0.72 45.02 6.51
85 INT130875 Gene_expression of ADAM17 13 0.78 15.46 6.41
86 INT105157 Positive_regulation of Phosphorylation of Gfap 8 0.67 6.48 6.38
87 INT81443 Positive_regulation of Vcam1 29 0.63 28.4 6.35
88 INT14560 Regulation of Igf1 41 0.59 19.59 6.3
89 INT127023 Negative_regulation of Gene_expression of Vcam1 24 0.59 20.39 6.28
90 INT9494 Positive_regulation of Gene_expression of Igf1 34 0.67 17.77 6.26
91 INT9495 Negative_regulation of Gene_expression of Igf1 31 0.59 11.87 6.1
92 INT9321 Transcription of Igf1 25 0.69 10.2 6.08
93 INT8916 Regulation of Igf1 45 0.60 13.06 5.81
94 INT71727 Negative_regulation of Icam1 25 0.45 17.76 5.73
95 INT151032 Localization of Igf1 49 0.76 26.32 5.71
96 INT83597 Phosphorylation of Ptk2 20 0.82 3.24 5.7
97 INT55733 Negative_regulation of VTN 47 0.58 47.22 5.68
98 INT112124 Positive_regulation of Egfr 71 0.70 47.82 5.61
99 INT242528 Gene_expression of Gfra1 15 0.09 1.17 5.61
100 INT32458 Gene_expression of VWF 57 0.78 28.97 5.56
101 INT113254 Positive_regulation of MFGE8 13 0.09 2.52 5.56
102 INT157802 Negative_regulation of Timp2 7 0.54 5.75 5.51
103 INT65712 Positive_regulation of Localization of ICAM1 14 0.70 16.72 5.5
104 INT82611 Negative_regulation of SRC 30 0.57 20.16 5.47
105 INT13396 Gene_expression of DMD 125 0.75 57.81 5.45
106 INT124370 Positive_regulation of Gene_expression of Gsk3b 47 0.67 24.56 5.4
107 INT213741 Gene_expression of Kdr 60 0.75 44.24 5.35
108 INT95696 Gene_expression of Dmd 130 0.68 26.02 5.34
109 INT144946 Localization of Icam1 21 0.75 21.84 5.33
110 INT56445 Regulation of Icam1 14 0.39 15.4 5.32
111 INT18681 Gene_expression of Thy1 80 0.71 38.8 5.23
112 INT10888 Binding of Vwf 32 0.46 22.87 5.21
113 INT94433 Negative_regulation of TIMP2 16 0.55 9.38 4.78
114 INT479 Positive_regulation of Gfra1 25 0.69 10.71 4.76
115 INT135374 Binding of Gsk3b 46 0.48 24.36 4.75
116 INT94453 Gene_expression of ITGB1 50 0.75 18.41 4.72
117 INT2725 Positive_regulation of FCER2 23 0.69 23.08 4.7
118 INT53784 Positive_regulation of Regulation of Gfap 7 0.50 3.31 4.68
119 INT74447 Gene_expression of Vwf 39 0.76 21.96 4.66
120 INT92682 Positive_regulation of Gene_expression of Ctgf 17 0.69 12.16 4.51
121 INT107605 Gene_expression of MMP14 26 0.64 25.88 4.49
122 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45
123 INT62821 Negative_regulation of Gene_expression of VCAM1 21 0.54 12.24 4.41
124 INT104299 Negative_regulation of Adam17 18 0.47 12.03 4.39
125 INT5838 Negative_regulation of Positive_regulation of Gfap 10 0.58 6.52 4.39
126 INT103155 Gene_expression of KDR 78 0.66 50.53 4.38
127 INT50713 Positive_regulation of Nisch 6 0.69 1.5 4.33
128 INT22973 Gene_expression of Col3a1 22 0.42 15.85 4.32
129 INT103914 Phosphorylation of Egfr 35 0.82 16.98 4.31
130 INT130083 Positive_regulation of Positive_regulation of Vcam1 8 0.36 5.81 4.31
131 INT55743 Gene_expression of Timp2 25 0.31 8.95 4.3
132 INT18785 Binding of Nisch 12 0.43 1.03 4.28
133 INT66366 Positive_regulation of Gsk3b 15 0.68 6.56 4.27
134 INT49360 Localization of Igf1 22 0.76 6.96 4.26
135 INT167284 Phosphorylation of Gsk3b 88 0.82 36.03 4.21
136 INT113485 Localization of MMP14 11 0.77 3.44 4.19
137 INT15001 Localization of Gfap 29 0.75 6.71 4.1
138 INT170738 Binding of Icam1 23 0.37 25.49 4.09
139 INT62545 Regulation of Gene_expression of Icam1 17 0.49 14.26 4.06
140 INT91998 Positive_regulation of Transcription of Gfra1 6 0.47 4.14 3.87
141 INT116642 Negative_regulation of Gsk3b 13 0.57 7.16 3.83
142 INT142174 Regulation of Gene_expression of Igf1 28 0.60 11.86 3.77
143 INT120715 Positive_regulation of Egfr 15 0.68 5.53 3.77
144 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75
145 INT70996 Positive_regulation of Positive_regulation of Icam1 8 0.60 6.02 3.74
146 INT52227 Gene_expression of CD9 11 0.75 6.23 3.71
147 INT117773 Positive_regulation of Phosphorylation of Ptk2 9 0.69 0.89 3.71
148 INT93120 Localization of Gfap 21 0.78 8.42 3.7
149 INT289208 Gene_expression of MFGE8 13 0.08 0.25 3.7
150 INT10146 Negative_regulation of Vwf 27 0.40 17.11 3.69
151 INT119506 Negative_regulation of Egfr 32 0.55 23.75 3.67
152 INT134914 Binding of Gfap 21 0.37 8.25 3.67
153 INT11761 Negative_regulation of DST 13 0.42 7.66 3.65
154 INT16165 Regulation of DMD 114 0.60 35.13 3.64
155 INT15002 Regulation of Gfap 17 0.37 5.34 3.61
156 INT91994 Regulation of Gene_expression of Gfra1 5 0.42 6 3.6
157 INT106264 Negative_regulation of Gene_expression of Vcam1 13 0.53 10.47 3.55
158 INT228465 Positive_regulation of Timp2 4 0.64 6.29 3.54
159 INT135373 Regulation of Gsk3b 35 0.62 18.11 3.53
160 INT102076 Regulation of DST 15 0.22 10 3.5
161 INT130351 Positive_regulation of Vwf 18 0.59 5.99 3.48
162 INT92681 Positive_regulation of Ctgf 13 0.69 9.78 3.47
163 INT113604 Negative_regulation of Gene_expression of Ctgf 19 0.58 9.37 3.43
164 INT20586 Regulation of Gfra1 20 0.51 9.43 3.41
165 INT66198 Negative_regulation of Gene_expression of Gfap 13 0.59 10.33 3.41
166 INT171998 Binding of DMD 58 0.47 38.13 3.35
167 INT105537 Regulation of Gene_expression of Igf1 15 0.58 6.97 3.23
168 INT155039 Gene_expression of ADAMTS5 23 0.67 7.85 3.22
169 INT163066 Transcription of Gfap 12 0.69 4.47 3.21
170 INT36032 Gene_expression of Col3a1 23 0.72 10.55 3.18
171 INT215926 Regulation of Gene_expression of Mmp14 1 0.45 5.33 3.15
172 INT179338 Gene_expression of Timp2 7 0.55 5.75 3.13
173 INT124954 Gene_expression of Egfr 26 0.75 15.08 3.12
174 INT70994 Negative_regulation of Positive_regulation of Icam1 8 0.51 3.49 3.12
175 INT120562 Negative_regulation of Egfr 108 0.59 79.38 3.11
176 INT100688 Gene_expression of SRC 28 0.75 15.51 3.08
177 INT66367 Gene_expression of Gsk3b 16 0.45 9.75 3.07
178 INT55409 Localization of VWF 17 0.80 8.99 3.06
179 INT65916 Gene_expression of LAMB1 13 0.55 3.09 3.06
180 INT77604 Positive_regulation of Binding of VCAM1 4 0.47 6.54 3.06
181 INT131187 Regulation of Gene_expression of IGF1 18 0.62 11.18 3.05
182 INT271442 Positive_regulation of Thy1 10 0.40 6.64 3.05
183 INT24821 Binding of VTN 14 0.47 5.83 3
184 INT16130 Binding of IGF1 67 0.48 27.43 2.95
185 INT51099 Negative_regulation of Nisch 6 0.43 0.97 2.93
186 INT126323 Regulation of TGFBI 6 0.59 3.17 2.9
187 INT77602 Binding of VCAM1 8 0.41 8.66 2.86
188 INT102157 Gene_expression of Adam17 3 0.58 4.17 2.86
189 INT10893 Binding of VWF 27 0.47 25.02 2.82
190 INT10516 Localization of Vwf 30 0.79 7.54 2.77
191 INT99895 Positive_regulation of Mmp14 10 0.58 6.64 2.72
192 INT74216 Binding of Icam1 16 0.48 10.11 2.69
193 INT289211 Localization of MFGE8 11 0.09 0.19 2.69
194 INT79938 Regulation of Gene_expression of VCAM1 12 0.61 11.22 2.64
195 INT111298 Gene_expression of ACTN4 12 0.70 9.42 2.6
196 INT66199 Negative_regulation of Gfap 14 0.46 6.88 2.57
197 INT52228 Negative_regulation of Gene_expression of CD9 3 0.57 2.45 2.54
198 INT32421 Gene_expression of FCER2 19 0.73 17.23 2.53
199 INT99897 Positive_regulation of Gene_expression of Mmp14 7 0.36 6.33 2.51
200 INT34545 Positive_regulation of L1cam 12 0.60 1.18 2.5
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