GO:0005179

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Name hormone activity
Categary Function
Go Slim No
Go Link GO:0005179
Unique Molecular Interactions 7454
Total Molecular Interactions 11323
Total Single Events 124870
Pain Genes Associated 161

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for hormone activity. They are ordered first by their pain relevance and then by number of times they were reported for hormone activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69872 Binding of MC1R and POMC 52 0.54 8.87 18.3
2 INT6078 Pomc Positive_regulation of Localization of Penk 13 0.51 0 15.49
3 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 0.64 2.12 14.2
4 INT166591 Binding of CALCA and DCLK3 4 0.30 0.69 12.18
5 INT10161 Binding of Cck and Penk 6 0.53 0.97 11.15
6 INT10268 Binding of PDYN and POMC 11 0.39 0.08 10.36
7 INT6079 Pomc Positive_regulation of Penk 9 0.43 0 9.46
8 INT26468 Ghrh Positive_regulation of Localization of Gh 21 0.37 3.26 9.21
9 INT2714 Pomc Positive_regulation of Localization of Prl 17 0.79 0.5 8.18
10 INT11250 Cck Positive_regulation of Gene_expression of Fos 14 0.78 0.08 7.29
11 INT31439 Penk Positive_regulation of Localization of Prl 8 0.55 0.23 6.24
12 INT91538 Pomc Positive_regulation of P9Ehs1 6 0.11 1.47 6.23
13 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
14 INT92466 Pomc Positive_regulation of Binding of Crygs 8 0.06 0 5.56
15 INT20133 Trh Positive_regulation of Localization of Prl 23 0.78 2.04 5.44
16 INT15842 Crh Positive_regulation of Localization of Pomc 15 0.73 5 5.05
17 INT1310 Pomc Regulation of Localization of Prl 9 0.40 0.61 4.96
18 INT10844 Ghrh Regulation of Gh 13 0.13 4.77 4.71
19 INT29206 Crh Regulation of Localization of POMC 4 0.64 0.96 4.68
20 INT24742 Binding of Calca and Vip 1 0.37 0.18 4.68
21 INT51497 Cck Negative_regulation of Localization of Trim13 1 0.34 0 4.53
22 INT32444 Binding of Cpe and Pomc 2 0.22 0 4.47
23 INT30423 Penk Regulation of Localization of Ins1 4 0.26 0.77 4.42
24 INT1390 Trh Positive_regulation of Prl 14 0.67 4.42 4.39
25 INT1392 Trh Regulation of Prl 15 0.29 2.47 4.29
26 INT113223 POMC Regulation of MC1R 6 0.68 0.39 4.24
27 INT1313 Pomc Positive_regulation of Prl 7 0.35 0 4.19
28 INT11613 Cck Positive_regulation of Localization of Oxt 3 0.53 0 4.17
29 INT31440 Penk Positive_regulation of Prl 7 0.76 0 4.1
30 INT16221 Ghrh Positive_regulation of Gh 8 0.21 1.89 4.08
31 INT29240 Binding of POMC and YY1 5 0.40 0.17 4.06
32 INT34220 Binding of POMC and Oprl1 4 0.01 0.25 4.05
33 INT11248 Gh Positive_regulation of Ghrh 2 0.26 0.09 4.04
34 INT2169 Penk Regulation of Localization of Prl 6 0.48 0 4.03
35 INT13969 Binding of Calca and Sst 3 0.32 0.6 4.02
36 INT20456 Binding of Pomc and Penk 9 0.41 0.26 3.93
37 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91
38 INT107801 Ugt1a5 Positive_regulation of Localization of Prl 3 0.76 1 3.9
39 INT11252 Cck Positive_regulation of Fos 6 0.78 0 3.79
40 INT69938 Cck Positive_regulation of Localization of Abat 2 0.29 0 3.78
41 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
42 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35
43 INT7436 CFP Positive_regulation of Binding of POMC 1 0.02 0.18 3.35
44 INT108471 Binding of CALCA and PNOC 1 0.29 0.64 3.25
45 INT3434 Vip Positive_regulation of Localization of Prl 6 0.76 0.16 3.21
46 INT13729 GHRH Positive_regulation of Localization of GH1 13 0.62 0.59 3.2
47 INT29657 Binding of Calca and Calcb 1 0.26 0 3.16
48 INT17456 Binding of CSF2 and POMC 3 0.32 4.06 3.15
49 INT6076 Negative_regulation of Pomc Positive_regulation of Penk 3 0.31 0 3.14
50 INT30424 Penk Regulation of Localization of Sst 1 0.20 0 3.1
51 INT81708 POMC Regulation of Gene_expression of ITGAM 1 0.53 0.72 3.1
52 INT1151 Binding of CCK and GAST 7 0.49 0.73 3.08
53 INT40660 Pdyn Positive_regulation of Localization of Prl 1 0.27 0 3.01
54 INT28235 Binding of Cck and Gast 5 0.38 0.73 2.96
55 INT202965 Binding of STC2 and BAG3 1 0.02 7.86 2.96
56 INT166592 Binding of CALCA and RAMP1 2 0.35 0.33 2.91
57 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
58 INT134212 CRH Regulation of Localization of POMC 1 0.47 2.89 2.9
59 INT69937 Cck Positive_regulation of Abat 2 0.31 0 2.88
60 INT194409 Binding of CALCA and IGKV1D-8 1 0.15 0 2.84
61 INT32656 Pomc Positive_regulation of Rbm39 1 0.08 0.42 2.84
62 INT107723 POMC Positive_regulation of MC1R 7 0.68 0.71 2.82
63 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
64 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78
65 INT226118 Ghrl Regulation of Prkag1 1 0.08 0.72 2.72
66 INT30133 Binding of Cck and Penk 1 0.27 2.49 2.71
67 INT151381 St8sia1 Positive_regulation of Cck 1 0.19 0.45 2.7
68 INT278948 LEP Positive_regulation of Gene_expression of PTGER2 1 0.09 4.04 2.69
69 INT30345 Pomc Regulation of Localization of Penk 3 0.31 0 2.61
70 INT67663 Ins1 Positive_regulation of Ntrk2 1 0.00 0.19 2.59
71 INT29446 Crh Positive_regulation of Localization of POMC 8 0.38 1.87 2.58
72 INT111787 Cck Regulation of Gene_expression of Npr1 1 0.22 1.68 2.57
73 INT111789 Cck Regulation of Gene_expression of Penk 1 0.49 1.68 2.57
74 INT111786 Penk Regulation of Gene_expression of Cck 1 0.49 1.66 2.55
75 INT26892 OGG1 Negative_regulation of Gene_expression of Gh1 1 0.12 0 2.53
76 INT107812 Nppa Positive_regulation of Localization of Sst 1 0.48 0.54 2.51
77 INT20411 Ghrh Positive_regulation of Gh1 6 0.56 0.62 2.47
78 INT130284 Ins1 Negative_regulation of Gene_expression of Npy 1 0.32 0.1 2.47
79 INT21520 Crh Regulation of Pomc 3 0.22 0.4 2.45
80 INT56726 Cpe Negative_regulation of Pomc 1 0.07 0 2.41
81 INT214144 Cck Positive_regulation of Pomc 1 0.15 0.94 2.39
82 INT214159 Cck Positive_regulation of Nts 1 0.03 0.93 2.34
83 INT14781 Cck Regulation of Gast 3 0.38 0.28 2.3
84 INT13967 Calca Positive_regulation of Sst 1 0.45 0 2.3
85 INT152900 TRPV1 Regulation of Gene_expression of CALCA 1 0.69 0.73 2.29
86 INT152901 TRPV1 Regulation of Localization of CALCA 1 0.44 0.73 2.29
87 INT7367 Ghrh Regulation of Localization of Gh1 5 0.49 1.55 2.25
88 INT91860 Npy Regulation of Npy1r 2 0.28 1.13 2.24
89 INT51317 Binding of POMC and OR5D2P 1 0.00 0.6 2.23
90 INT34310 CRH Positive_regulation of POMC 3 0.42 0.62 2.21
91 INT32586 H2-Ab1 Regulation of Pomc 1 0.03 0.14 2.19
92 INT9180 Ghrh Regulation of Localization of Gh 3 0.24 0.25 2.18
93 INT1315 Pomc Positive_regulation of Localization of Gnrhr 3 0.38 0.16 2.16
94 INT5486 Oprd1 Regulation of Cck 1 0.21 0 2.16
95 INT49242 Binding of Mc1r and Pomc 10 0.38 3.79 2.15
96 INT3576 Sst Negative_regulation of Localization of Gh1 6 0.23 0 2.13
97 INT240131 Binding of Crp and Nppb 7 0.07 11.53 2.12
98 INT18593 Binding of Sst and Fdft1 2 0.11 0.08 2.12
99 INT356313 Crh Positive_regulation of Localization of Helt 1 0.02 0 2.11
100 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
101 INT63919 Binding of Cck and Insrr 1 0.01 0 2.08
102 INT28387 Pomc Positive_regulation of Localization of LH 2 0.40 0.28 2.07
103 INT63918 Binding of Cck and Ripk2 1 0.28 0 2.07
104 INT134215 CRH Positive_regulation of ENG 1 0.13 1.22 2.06
105 INT202963 Binding of STC2 and CPP 1 0.02 5.16 2.04
106 INT18355 Penk Positive_regulation of Localization of Sst 1 0.31 0 2.04
107 INT26221 Calca Regulation of Gt(pU21)50Imeg 1 0.01 0 2.02
108 INT138962 Dbi Positive_regulation of Pomc 1 0.00 1.53 2
109 INT32585 H2-Ab1 Negative_regulation of Pomc 1 0.03 0.13 2
110 INT60626 Crh Positive_regulation of Localization of Pomc 7 0.54 2.3 1.99
111 INT26948 Pomc Positive_regulation of Localization of Gh1 2 0.22 0.15 1.99
112 INT213968 Binding of Calca and Mthfd1 1 0.05 0.16 1.99
113 INT45423 Avp Positive_regulation of Localization of Prl 4 0.67 1.37 1.98
114 INT87891 Agt Regulation of Cck 1 0.28 0 1.97
115 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
116 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
117 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
118 INT264947 Binding of POMC and TLR2 1 0.03 0.89 1.95
119 INT13430 Abat Positive_regulation of Localization of Sst 2 0.33 0 1.94
120 INT165284 Positive_regulation of Nts Positive_regulation of Crh 1 0.40 1.86 1.93
121 INT149470 Oxt Regulation of Gene_expression of Avp 1 0.46 1.2 1.92
122 INT165285 Nts Positive_regulation of Crh 1 0.40 1.84 1.91
123 INT149469 Oxt Regulation of Gene_expression of Crh 1 0.45 1.2 1.91
124 INT91607 Binding of EDN1 and POMC 1 0.12 0 1.9
125 INT31438 Penk Positive_regulation of Localization of Pomc 1 0.18 0 1.9
126 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
127 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
128 INT13940 DNM2 Regulation of Localization of CGA 1 0.11 0 1.86
129 INT82867 Cck Regulation of Localization of Pgc 1 0.05 0 1.83
130 INT16891 GHRH Regulation of GH1 5 0.37 1.94 1.82
131 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82
132 INT19496 Pomc Regulation of Localization of Ins1 1 0.55 0.33 1.82
133 INT117269 Binding of Avp and Prl 1 0.25 0.47 1.8
134 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78
135 INT31445 ENG Positive_regulation of Localization of Prl 4 0.01 0 1.77
136 INT23392 Gal Regulation of Trpv1 1 0.05 0.33 1.77
137 INT13979 Gast Positive_regulation of Localization of Sst 3 0.69 0.05 1.75
138 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75
139 INT190981 Binding of Npy and Scn2a1 1 0.10 0 1.75
140 INT31534 Binding of Sst and Oprl1 2 0.16 0.53 1.74
141 INT57249 GNRH1 Regulation of Regulation of CGA 1 0.20 0 1.74
142 INT26676 Pomc Regulation of Localization of Trh 3 0.14 0 1.73
143 INT24817 Binding of POMC and VTN 8 0.42 0.39 1.71
144 INT148090 Binding of CALCA and NCOR2 1 0.00 0.65 1.71
145 INT10202 Agt Positive_regulation of Avp 3 0.70 0 1.69
146 INT160304 Npy Regulation of Gene_expression of Fos 3 0.67 1.43 1.68
147 INT56134 CALCA Positive_regulation of POMC 2 0.71 0.72 1.68
148 INT45306 Pomc Positive_regulation of ENG 2 0.07 1.11 1.68
149 INT353717 Binding of Ghrl and Vta1 1 0.15 0 1.68
150 INT102447 Binding of CALCA and CALCRL 2 0.26 0.33 1.67
151 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
152 INT18520 Adra2c Positive_regulation of Localization of Ins1 3 0.41 0.63 1.66
153 INT144213 Nppa Positive_regulation of Localization of Calca 1 0.71 2.8 1.65
154 INT24157 Binding of CALCA and SFTPA1 2 0.07 0.96 1.64
155 INT90658 Abat Regulation of Localization of Cck 2 0.24 0 1.64
156 INT30743 Cck Regulation of Localization of Acot1 1 0.02 0 1.64
157 INT67966 Cck Positive_regulation of Adarb1 2 0.03 0 1.63
158 INT32482 Ghrh Positive_regulation of Prl 3 0.18 0.26 1.62
159 INT32412 Penk Regulation of Pomc 3 0.21 0.36 1.62
160 INT86637 POMC Regulation of Gene_expression of KRT16 2 0.47 1.22 1.61
161 INT18592 Sst Regulation of Localization of Acot1 2 0.22 0 1.61
162 INT160578 Binding of CALCA and TAC1 1 0.07 0.91 1.61
163 INT94270 Pomc Regulation of Transcription of Crh 1 0.17 0.67 1.6
164 INT21570 Binding of Cck and Mapk8 1 0.06 0 1.6
165 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
166 INT66408 Pomc Positive_regulation of Regulation of HRH1 1 0.01 0 1.58
167 INT40827 Sstr1 Negative_regulation of Localization of Gh1 1 0.13 0 1.58
168 INT356327 Crh Positive_regulation of Localization of Gabrg1 1 0.17 0 1.58
169 INT41652 Binding of Pomc and Oprl1 3 0.16 0 1.57
170 INT42928 Penk Negative_regulation of Localization of Oxt 2 0.03 0 1.57
171 INT107815 Gene_expression of Sst Positive_regulation of Localization of Nppa 1 0.52 0.27 1.57
172 INT94271 Pomc Regulation of Avp 1 0.20 0.67 1.57
173 INT26985 Cpe Negative_regulation of Localization of Ins1 1 0.02 0 1.57
174 INT81710 POMC Regulation of Gene_expression of FCGR3B 1 0.50 0.34 1.57
175 INT81709 POMC Regulation of Gene_expression of ITGB2 1 0.40 0.34 1.57
176 INT81719 POMC Regulation of Gene_expression of ITGAL 1 0.35 0.34 1.57
177 INT7796 Akr1d1 Regulation of Npy 1 0.03 0 1.57
178 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
179 INT81712 POMC Regulation of FCGR3B 1 0.16 0.34 1.56
180 INT6768 Oprl1 Regulation of Localization of Prl 2 0.12 0 1.55
181 INT81715 POMC Regulation of ITGB2 1 0.40 0.34 1.55
182 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
183 INT81721 POMC Regulation of ITGAM 1 0.39 0.34 1.55
184 INT13968 Calca Negative_regulation of Positive_regulation of Sst 1 0.34 0 1.55
185 INT41100 Mdk Positive_regulation of Localization of INS 1 0.01 0 1.55
186 INT54844 Negative_regulation of Penk Positive_regulation of Vip 1 0.26 0 1.54
187 INT81714 POMC Regulation of ITGAL 1 0.15 0.34 1.54
188 INT7797 Akr1d1 Regulation of Sst 1 0.02 0 1.54
189 INT32152 POMC Positive_regulation of Gene_expression of IFNA1 2 0.67 0 1.53
190 INT13970 Positive_regulation of Calca Positive_regulation of Sst 1 0.37 0 1.53
191 INT13965 Calca Positive_regulation of Positive_regulation of Sst 1 0.37 0 1.53
192 INT41101 Mdk Negative_regulation of SST 1 0.02 0 1.53
193 INT23548 Negative_regulation of CNDP2 Negative_regulation of Localization of POMC 1 0.03 0 1.52
194 INT140017 Avp Positive_regulation of Gene_expression of Pomc 1 0.38 0.85 1.52
195 INT69709 NPL Positive_regulation of Localization of POMC 2 0.36 1.22 1.51
196 INT32657 Positive_regulation of Pomc Positive_regulation of Rbm39 1 0.08 0.22 1.51
197 INT76656 POMC Positive_regulation of Gene_expression of Il6 1 0.03 0 1.51
198 INT42001 Cck Regulation of Vip 1 0.28 0 1.51
199 INT260897 CRH Positive_regulation of Localization of IL8 1 0.24 0.09 1.51
200 INT140008 Avp Positive_regulation of Pomc 1 0.38 0.84 1.51

Single Events

The table below shows the top 100 pain related interactions that have been reported for hormone activity. They are ordered first by their pain relevance and then by number of times they were reported in hormone activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT158 Localization of Prl 2431 0.81 378.96 952.2
2 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82
3 INT443 Localization of POMC 1020 0.81 284.52 443.17
4 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16
5 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78
6 INT287 Localization of Cck 518 0.81 86.84 364.04
7 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83
8 INT876 Localization of Gh1 843 0.80 67.75 340.82
9 INT162 Regulation of Prl 794 0.62 165.01 322.24
10 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66
11 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98
12 INT2365 Positive_regulation of Cck 354 0.70 87.8 277.41
13 INT1893 Localization of Gh 1041 0.79 340.23 256.58
14 INT3948 Regulation of Cck 291 0.62 58.07 255.88
15 INT1005 Localization of Sst 385 0.81 26.31 244.56
16 INT738 Regulation of POMC 459 0.62 111.19 243.74
17 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92
18 INT626 Localization of CALCA 289 0.81 125.39 221.15
19 INT1308 Localization of Pomc 457 0.81 66.83 217.5
20 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24
21 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24
22 INT528 Gene_expression of Prl 693 0.78 217.18 192.2
23 INT1652 Regulation of Pomc 387 0.62 61.01 186.51
24 INT943 Negative_regulation of Cck 205 0.59 38.42 174.78
25 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8
26 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77
27 INT1114 Localization of Ins1 748 0.80 192.95 165.48
28 INT2366 Binding of Cck 192 0.48 30.64 163.46
29 INT5127 Localization of Lhb 488 0.80 50.48 162.66
30 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18
31 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63
32 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37
33 INT880 Positive_regulation of Localization of Gh1 304 0.70 14.79 150.23
34 INT6108 Gene_expression of Npy 292 0.78 110.65 148.21
35 INT812 Localization of INS 1026 0.81 515.6 145.31
36 INT425 Localization of PRL 455 0.81 189.64 144.8
37 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47
38 INT695 Binding of POMC 304 0.48 56.66 126.85
39 INT5008 Localization of Calca 204 0.81 80.35 125.16
40 INT252 Localization of GH1 529 0.80 227.4 122.05
41 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64
42 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75
43 INT7395 Localization of GNRH1 399 0.81 62.88 117.68
44 INT1438 Localization of Pomc 360 0.81 101.26 116.47
45 INT1793 Localization of CGA 379 0.81 67.38 114.69
46 INT90 Localization of Gast 400 0.81 137.67 113
47 INT1530 Regulation of Gh 382 0.61 115.96 112.47
48 INT7362 Gene_expression of Sst 185 0.78 41.73 111.37
49 INT5283 Positive_regulation of Npy 191 0.70 66.77 109.2
50 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01
51 INT9012 Localization of Vip 283 0.81 31.71 106.16
52 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31
53 INT397 Localization of SST 232 0.81 58.05 101.19
54 INT874 Positive_regulation of Gh1 244 0.70 27.17 97.98
55 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61
56 INT1004 Regulation of Sst 140 0.62 18.52 94.84
57 INT2862 Positive_regulation of Localization of Cck 108 0.70 20.75 94.25
58 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5
59 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84
60 INT1635 Gene_expression of Vip 245 0.78 53.36 88.13
61 INT1472 Positive_regulation of Ins1 349 0.69 146.2 86.36
62 INT875 Regulation of Localization of Gh1 166 0.62 12.87 84.97
63 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91
64 INT5617 Localization of Nppa 266 0.81 83.51 83.89
65 INT4631 Positive_regulation of Sst 127 0.70 17.37 83.29
66 INT8650 Gene_expression of Gal 152 0.78 61.97 81.72
67 INT6107 Localization of Npy 180 0.81 26.76 81.67
68 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16
69 INT2893 Localization of Oxt 219 0.80 28.96 79.43
70 INT3214 Localization of Ins1 527 0.80 196.9 79.26
71 INT2155 Negative_regulation of Sst 111 0.59 16.58 77.74
72 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76
73 INT881 Negative_regulation of Localization of Gh1 164 0.58 15.1 75.28
74 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71
75 INT5128 Positive_regulation of Lhb 232 0.69 44.23 71.26
76 INT1988 Positive_regulation of Localization of Ins1 254 0.69 59.25 68.37
77 INT8388 Positive_regulation of Vip 142 0.70 39.72 67.61
78 INT462 Regulation of Pomc 157 0.62 41.67 67.27
79 INT253 Regulation of PRL 184 0.62 47.27 65.79
80 INT8347 Gene_expression of SST 181 0.78 104.59 65.45
81 INT7280 Positive_regulation of Localization of Sst 97 0.70 5.64 63.37
82 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07
83 INT6761 Binding of CALCA 100 0.48 26.71 62.05
84 INT1437 Negative_regulation of Pomc 132 0.59 35.22 60.97
85 INT3161 Regulation of Localization of Gh 163 0.61 35.43 59.45
86 INT1794 Regulation of Localization of CGA 136 0.57 13.39 59.07
87 INT1307 Positive_regulation of Localization of Pomc 120 0.70 24.58 58.48
88 INT5710 Negative_regulation of Localization of Lhb 146 0.57 20.51 58.33
89 INT5453 Regulation of Localization of POMC 114 0.62 20.56 56.34
90 INT1463 Binding of Pomc 129 0.48 15.89 56.27
91 INT1200 Negative_regulation of Ins1 274 0.58 155.17 56.14
92 INT1782 Regulation of Gh1 125 0.62 22 55.74
93 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41
94 INT4241 Regulation of CALCA 87 0.62 28.19 55.29
95 INT251 Regulation of INS 398 0.62 232.47 55.04
96 INT8153 Regulation of Localization of Cck 52 0.62 11.22 54.83
97 INT5506 Positive_regulation of Gene_expression of Pomc 132 0.70 26.78 54.3
98 INT2276 Regulation of Ins1 234 0.61 103.78 54.05
99 INT3213 Gene_expression of Ins1 511 0.76 357.59 53.32
100 INT5623 Positive_regulation of Nppa 174 0.70 69.96 52.33
101 INT97674 Positive_regulation of Localization of Calca 70 0.69 27.71 51.79
102 INT1781 Negative_regulation of Gh1 127 0.59 16.94 51.77
103 INT5118 Regulation of SST 97 0.62 34.35 51.74
104 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34
105 INT5338 Regulation of Npy 92 0.62 25.54 51.24
106 INT5098 Negative_regulation of Localization of Sst 70 0.58 3.56 51.17
107 INT921 Regulation of GH1 172 0.60 52.88 51.04
108 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43
109 INT937 Positive_regulation of Oxt 195 0.70 37.82 49.3
110 INT51163 Gene_expression of Gal 119 0.78 67.48 49.23
111 INT6299 Regulation of Localization of Lhb 104 0.61 8.98 48.79
112 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31
113 INT1197 Negative_regulation of Localization of POMC 109 0.59 28.29 48.02
114 INT1977 Negative_regulation of Positive_regulation of Prl 98 0.59 17.06 47.88
115 INT2463 Localization of CCK 101 0.81 37.54 47.59
116 INT6544 Negative_regulation of Localization of Cck 67 0.59 8.05 47.23
117 INT5025 Positive_regulation of Gene_expression of Cck 63 0.70 10.96 47.11
118 INT873 Gene_expression of Gh1 130 0.76 26.15 46.75
119 INT5337 Negative_regulation of Npy 87 0.59 19.6 46.75
120 INT2406 Gene_expression of CCK 85 0.78 28.04 46.67
121 INT847 Regulation of Lhb 131 0.61 22.08 46.54
122 INT531 Gene_expression of GH1 376 0.75 193.45 46.24
123 INT5781 Gene_expression of Edn1 190 0.78 99.1 46
124 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98
125 INT619 Positive_regulation of Positive_regulation of Prl 116 0.70 22.69 45.06
126 INT2275 Negative_regulation of Localization of Ins1 183 0.59 51.02 44.94
127 INT2262 Negative_regulation of Lhb 142 0.59 25.47 44.81
128 INT8824 Regulation of Vip 95 0.62 15.7 43.63
129 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56
130 INT1474 Regulation of Localization of Ins1 132 0.61 25.96 43.07
131 INT1295 Binding of Pomc 85 0.48 12.92 42.8
132 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8
133 INT5130 Regulation of GNRH1 139 0.62 31.95 42.08
134 INT89 Positive_regulation of Gast 187 0.70 80.49 42.07
135 INT5454 Localization of CRH 124 0.79 79.18 41.53
136 INT2364 Localization of Sct 134 0.80 26.21 41.47
137 INT30 Gene_expression of Gast 158 0.78 99 41.45
138 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17
139 INT918 Positive_regulation of Localization of PRL 90 0.70 23.97 40.3
140 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52
141 INT7824 Regulation of Cck 39 0.62 5.31 39.28
142 INT2782 Regulation of Gene_expression of Pomc 75 0.62 15.04 38.97
143 INT1931 Positive_regulation of Gene_expression of POMC 116 0.70 37.26 38.67
144 INT65889 Gene_expression of RETNLB 73 0.34 60.98 38.3
145 INT916 Regulation of Localization of PRL 92 0.62 22.98 38.13
146 INT385 Gene_expression of Agt 182 0.78 63.62 37.91
147 INT12159 Transcription of Cck 46 0.72 9.36 37.58
148 INT5039 Positive_regulation of Gal 67 0.68 27.97 37.36
149 INT14009 Gene_expression of Sst 66 0.77 19.6 37.3
150 INT5711 Positive_regulation of Localization of Lhb 90 0.70 10.92 36.76
151 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61
152 INT5620 Positive_regulation of Localization of Nppa 105 0.70 30.23 36.45
153 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08
154 INT1976 Regulation of Gene_expression of Prl 80 0.62 20.19 36
155 INT927 Gene_expression of Oxt 184 0.78 44.71 35.79
156 INT3216 Positive_regulation of Localization of Ins1 170 0.69 56.78 35.63
157 INT14031 Gene_expression of Npy 107 0.78 36.48 35.4
158 INT2296 Positive_regulation of Gene_expression of Prl 137 0.70 36.96 35.39
159 INT255 Regulation of Localization of GH1 89 0.62 18.71 35.3
160 INT8747 Positive_regulation of Ins1 221 0.69 154.28 35.15
161 INT7282 Regulation of Localization of Sst 58 0.62 1.92 34.83
162 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79
163 INT692 Negative_regulation of SST 72 0.59 28.68 34.52
164 INT7833 Positive_regulation of Cck 33 0.70 8.54 34.21
165 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19
166 INT14559 Gene_expression of Igf1 254 0.78 112 34.17
167 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45
168 INT248 Positive_regulation of Localization of GH1 137 0.69 49.25 32.92
169 INT5868 Positive_regulation of GNRH1 122 0.69 20.96 32.8
170 INT691 Binding of SST 67 0.48 24.66 32.67
171 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51
172 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39
173 INT3117 Regulation of Oxt 103 0.61 17.93 32.28
174 INT13897 Localization of Sst 65 0.81 14.91 32.24
175 INT9796 Gene_expression of Cck 63 0.78 11.44 32.09
176 INT7082 Gene_expression of CRH 180 0.78 64.66 31.74
177 INT1159 Negative_regulation of Agt 133 0.59 40.14 31.67
178 INT7396 Regulation of Localization of GNRH1 81 0.62 6.57 31.31
179 INT6277 Positive_regulation of Gene_expression of Pomc 76 0.70 21.45 31.09
180 INT15347 Positive_regulation of Localization of Pomc 81 0.70 28.1 31.01
181 INT5505 Regulation of Localization of Pomc 54 0.61 6.96 30.77
182 INT2278 Regulation of Localization of Gast 81 0.62 16.93 30.64
183 INT2884 Positive_regulation of CCK 66 0.69 25.25 30.6
184 INT1473 Localization of Gcg 95 0.80 17.35 30.31
185 INT1158 Regulation of Agt 106 0.61 29.4 30.29
186 INT6196 Regulation of Nppa 83 0.62 30.31 30.18
187 INT28 Regulation of Gast 106 0.62 26.37 29.85
188 INT7397 Negative_regulation of Localization of GNRH1 86 0.59 15.45 29.78
189 INT7412 Positive_regulation of SST 71 0.70 24.44 29.48
190 INT91 Positive_regulation of Localization of Gast 96 0.70 23.22 29.36
191 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76
192 INT1196 Positive_regulation of Positive_regulation of POMC 51 0.70 15.99 28.58
193 INT7035 Regulation of CGA 87 0.45 29.04 28.45
194 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43
195 INT22499 Regulation of Calca 42 0.62 17.32 28.02
196 INT52722 Localization of RETNLB 54 0.38 48.63 27.98
197 INT5135 Negative_regulation of GNRH1 106 0.58 36.63 27.71
198 INT6174 Regulation of Gene_expression of POMC 49 0.61 9.75 27.69
199 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54
200 INT7565 Transcription of Pomc 69 0.72 14.46 27.41
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