GO:0005212

From wiki-pain
Jump to: navigation, search
Name structural constituent of eye lens
Categary Function
Go Slim No
Go Link GO:0005212
Unique Molecular Interactions 90
Total Molecular Interactions 146
Total Single Events 1473
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for structural constituent of eye lens. They are ordered first by their pain relevance and then by number of times they were reported for structural constituent of eye lens. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT92466 Pomc Positive_regulation of Binding of Crygs 8 0.06 0 5.56
2 INT229497 Binding of Vim and Ndel1 1 0.33 3.5 2.81
3 INT108385 Binding of Crygs and Ntrk1 1 0.01 0 1.67
4 INT334131 Acsm3 Positive_regulation of Mip 1 0.13 3.12 1.48
5 INT240730 Binding of CRYGD and MTRF1 4 0.03 4.18 1.39
6 INT114007 Binding of Crygs and Oprm1 1 0.03 0 1.09
7 INT127738 Binding of Crygb and Pnoc 2 0.49 0.1 0.99
8 INT128653 ITIH4 Regulation of Gene_expression of MIP 1 0.23 1.44 0.92
9 INT89314 Binding of CRYGS and OPRM1 1 0.07 0.08 0.91
10 INT334130 Negative_regulation of Acsm3 Positive_regulation of Mip 1 0.12 1.48 0.81
11 INT334134 Acsm3 Positive_regulation of Gene_expression of Mip 1 0.13 1.4 0.77
12 INT98572 Binding of ABAT and CRYGS 1 0.01 0 0.75
13 INT199395 Mip Positive_regulation of Positive_regulation of Trpv1 1 0.01 0.86 0.69
14 INT81832 Binding of ADRA2C and CRYGS 1 0.06 0 0.66
15 INT288266 Binding of AFA and CRYGD 1 0.08 1.85 0.64
16 INT109256 PDYN Positive_regulation of Binding of CRYGS 1 0.00 0.1 0.61
17 INT86088 Foxm1 Positive_regulation of Binding of Crygs 1 0.04 0 0.49
18 INT86089 Foxm1 Regulation of Binding of Crygs 1 0.02 0 0.49
19 INT79624 CDC42BPG Positive_regulation of Binding of CRYGS 1 0.02 0.25 0.46
20 INT335996 Mmp8 Regulation of Protein_catabolism of MIP 1 0.44 1.06 0.43
21 INT249607 Binding of nct and Cts 1 0.19 0.43 0.43
22 INT127543 Gria1 Positive_regulation of Gene_expression of Cryge 1 0.00 0.35 0.42
23 INT160245 Binding of Col11a1 and Crygs 1 0.00 0.17 0.4
24 INT20974 SLC26A2 Negative_regulation of Binding of CRYGS 1 0.00 0 0.39
25 INT346227 Binding of PRTN3 and Vim 1 0.01 0.93 0.38
26 INT70836 Positive_regulation of OPRK1 Positive_regulation of Binding of CRYGS 1 0.03 0.09 0.36
27 INT155478 Binding of Gast and Vim 1 0.51 0.6 0.35
28 INT153019 nct Positive_regulation of Transcription of Th 1 0.19 0.61 0.32
29 INT153020 nct Positive_regulation of Gene_expression of Th 1 0.19 0.61 0.32
30 INT264504 Binding of CRYGD and PTPN22 1 0.04 0.42 0.31
31 INT128541 Pnoc Positive_regulation of Crygb 1 0.21 0 0.29
32 INT109711 Mip Positive_regulation of Rtcd1 1 0.00 0 0.29
33 INT268768 Mip Regulation of Positive_regulation of Ccr1 1 0.44 0.83 0.23
34 INT229502 Binding of Vim and Gopc 1 0.05 0.42 0.23
35 INT217349 Mip Positive_regulation of IL8 1 0.05 1.28 0.22
36 INT163863 Binding of MIB1 and Vim 1 0.02 1.06 0.21
37 INT182634 Binding of CCR5 and MIP 2 0.39 1.29 0.2
38 INT81833 Negative_regulation of Binding of ADRA2C and CRYGS 1 0.06 0 0.19
39 INT251528 Binding of CRYGD and NEUROG1 1 0.00 0.38 0.15
40 INT236303 Negative_regulation of IGKV2D-38 Positive_regulation of CRYGD 1 0.00 0.5 0.14
41 INT81831 Positive_regulation of Binding of ADRA2C and CRYGS 1 0.07 0 0.14
42 INT4987 Vim Positive_regulation of Lrrc23 1 0.00 0.42 0.14
43 INT236316 IGKV2D-38 Positive_regulation of CRYGD 1 0.00 0.5 0.14
44 INT148593 Binding of Gfap and Vim 1 0.06 1.25 0.13
45 INT251529 MTRF1 Positive_regulation of CRYGD 1 0.00 0.31 0.12
46 INT182367 IgG Regulation of Vim 1 0.00 0.99 0.11
47 INT279408 Binding of CRYGD and IGKV2-19 1 0.00 0.4 0.1
48 INT137398 Binding of CD99 and Vim 2 0.02 2.36 0.09
49 INT52944 Binding of SERPINA3 and Vim 1 0.01 0.43 0.09
50 INT157738 GFAP Regulation of Vim 1 0.04 0.97 0.08
51 INT68004 Binding of Hba-a1 and Vim 1 0.00 1.3 0.08
52 INT229501 Binding of Nefl and Vim 1 0.05 0.32 0.08
53 INT229500 Binding of Vim and Nde1 1 0.00 0.79 0.07
54 INT341680 Binding of DES and Vim 1 0.02 0.59 0.06
55 INT267214 Hspb8 Negative_regulation of Cryab 1 0.32 1.56 0.06
56 INT246451 Lta Positive_regulation of nct 1 0.14 0 0.04
57 INT229490 Binding of Vim and Kpna4 1 0.02 0.21 0.04
58 INT229499 Nde1 Regulation of Vim 1 0.00 0.35 0.04
59 INT229505 Ndel1 Negative_regulation of Vim 1 0.29 0.14 0.04
60 INT229498 Binding of Vim and Mapk1 1 0.03 0.21 0.04
61 INT236305 Binding of CRYGD and IGKV2D-38 1 0.00 0.36 0.03
62 INT182688 Binding of Vim and Fig4 1 0.08 0.07 0
63 INT341005 Binding of Vim and Nrg1 1 0.05 0.14 0
64 INT182685 Binding of Vim and Son 1 0.22 0.23 0
65 INT341025 PIK3CB Positive_regulation of Regulation of Vim 1 0.01 0 0
66 INT298451 Binding of SNAI1 and Vim 1 0.07 1.45 0
67 INT296670 Binding of Bcl2 and Vim 1 0.00 1.31 0
68 INT341012 Binding of Fabp7 and Vim 1 0.03 0.16 0
69 INT267215 Binding of Cryab and Hspb1 1 0.25 7.19 0
70 INT155479 Vim Positive_regulation of Gast 1 0.47 0 0
71 INT298449 Binding of ITK and Vim 1 0.01 0.58 0
72 INT341001 Binding of Reln and Vim 1 0.02 0.14 0
73 INT256992 Binding of Slc9a3r1 and Hspb6 1 0.09 0 0
74 INT267216 Binding of Cryab and Hspb8 1 0.36 9.29 0
75 INT341010 Nrg1 Positive_regulation of Regulation of Vim 1 0.07 0 0
76 INT185273 Vim Regulation of Psmd1 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for structural constituent of eye lens. They are ordered first by their pain relevance and then by number of times they were reported in structural constituent of eye lens. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT71995 Binding of Crygs 54 0.11 10.03 39.31
2 INT20976 Binding of CRYGS 39 0.46 5.4 20.09
3 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33
4 INT143230 Gene_expression of CRYGD 61 0.65 52.11 15.93
5 INT89740 Positive_regulation of Binding of Crygs 21 0.13 2.7 14.6
6 INT69867 Gene_expression of Mip 36 0.75 24.54 10.38
7 INT83292 Gene_expression of MIP 35 0.75 25.22 10.14
8 INT4991 Positive_regulation of Vim 74 0.69 69.84 8.33
9 INT122080 Positive_regulation of Crygb 10 0.45 4.32 7.14
10 INT26585 Gene_expression of Vim 117 0.77 39.97 6
11 INT147514 Negative_regulation of CRYGD 15 0.13 9.41 5.1
12 INT110520 Negative_regulation of Crygb 6 0.31 2.32 4.71
13 INT70837 Positive_regulation of Binding of CRYGS 10 0.45 0.63 4.64
14 INT122078 Gene_expression of Crygb 7 0.76 1.25 4.34
15 INT143231 Positive_regulation of CRYGD 20 0.49 14.87 3.67
16 INT77177 Negative_regulation of Binding of Crygs 5 0.13 1.94 3.1
17 INT110521 Regulation of Crygb 5 0.28 1.42 2.92
18 INT82885 Gene_expression of Mip 7 0.65 7.89 2.76
19 INT86713 Positive_regulation of Mip 10 0.67 6.44 2.63
20 INT27935 Binding of Vim 21 0.36 15.65 2.61
21 INT122332 Binding of Crygb 2 0.48 0 2.55
22 INT119210 Positive_regulation of Cryge 1 0.02 0.16 2.29
23 INT83294 Regulation of MIP 4 0.60 3.91 2.21
24 INT5844 Positive_regulation of Gene_expression of Vim 14 0.25 9.64 2.18
25 INT23955 Regulation of Vim 16 0.25 14.21 2.04
26 INT83293 Negative_regulation of MIP 2 0.41 4.12 2.02
27 INT82886 Positive_regulation of Mip 7 0.49 3.61 1.89
28 INT122077 Positive_regulation of Gene_expression of Crygb 1 0.32 0.09 1.87
29 INT112971 Positive_regulation of Gene_expression of MIP 3 0.49 5.24 1.82
30 INT91336 Localization of MIP 5 0.78 2.97 1.79
31 INT83291 Regulation of Gene_expression of MIP 2 0.60 2 1.79
32 INT194584 Regulation of CRYGD 6 0.20 4.33 1.71
33 INT210590 Positive_regulation of Gene_expression of Mip 10 0.67 8.09 1.68
34 INT108383 Positive_regulation of Crygs 1 0.04 0 1.65
35 INT187063 Binding of CRYGD 5 0.36 5.71 1.59
36 INT45390 Negative_regulation of Mip 2 0.20 0.21 1.41
37 INT229479 Positive_regulation of Vim 14 0.43 1.77 1.35
38 INT69863 Binding of Mip 7 0.36 4.54 1.33
39 INT32101 Regulation of Mip 3 0.26 0.89 1.31
40 INT79626 Negative_regulation of Binding of CRYGS 3 0.42 0.36 1.28
41 INT289973 Negative_regulation of Gene_expression of MIP 2 0.41 2.69 1.15
42 INT119208 Positive_regulation of Positive_regulation of Cryge 1 0.01 0.08 1.15
43 INT155477 Binding of Vim 13 0.47 2.24 1.12
44 INT194585 Localization of CRYGD 6 0.73 2.96 1.12
45 INT268763 Negative_regulation of Mip 3 0.41 2.61 1.12
46 INT169703 Positive_regulation of Gene_expression of Vim 7 0.38 2.56 1.09
47 INT165962 Transcription of Vim 3 0.39 1.47 1.01
48 INT101050 Localization of Mip 4 0.78 1.9 0.93
49 INT153016 Gene_expression of nct 4 0.32 0.97 0.89
50 INT169707 Regulation of Gene_expression of Vim 3 0.29 1.11 0.88
51 INT194583 Positive_regulation of Gene_expression of CRYGD 4 0.02 1.38 0.85
52 INT153015 Positive_regulation of Gene_expression of nct 3 0.24 0.9 0.74
53 INT76005 Regulation of Binding of Vim 1 0.02 0 0.72
54 INT334126 Positive_regulation of Positive_regulation of Mip 1 0.20 1.65 0.67
55 INT144010 Gene_expression of Hspb6 11 0.78 2.4 0.66
56 INT91332 Regulation of Localization of MIP 1 0.44 0.75 0.6
57 INT210075 Positive_regulation of MIP 3 0.67 0.98 0.56
58 INT77176 Negative_regulation of Crygs 1 0.03 0 0.53
59 INT77175 Regulation of Binding of Crygs 1 0.02 0 0.52
60 INT268755 Negative_regulation of Gene_expression of Mip 1 0.41 1.73 0.51
61 INT229465 Localization of Vim 6 0.47 1.23 0.47
62 INT143229 Positive_regulation of Positive_regulation of CRYGD 2 0.49 2.49 0.47
63 INT194587 Negative_regulation of Gene_expression of CRYGD 1 0.02 0.78 0.47
64 INT166312 Negative_regulation of Vim 7 0.22 5.9 0.46
65 INT194592 Regulation of Gene_expression of CRYGD 1 0.02 0.69 0.45
66 INT183187 Transcription of Mip 2 0.69 0.69 0.43
67 INT335992 Protein_catabolism of MIP 1 0.86 1.04 0.42
68 INT76690 Negative_regulation of Gene_expression of Vim 1 0.39 1.4 0.42
69 INT127539 Positive_regulation of Gene_expression of Cryge 1 0.00 0.35 0.42
70 INT91568 Gene_expression of CRYGS 1 0.03 0 0.42
71 INT166698 Localization of Vim 3 0.18 1.13 0.4
72 INT268751 Positive_regulation of Binding of Mip 1 0.49 0.91 0.4
73 INT138976 Binding of Mip 3 0.30 0.17 0.39
74 INT267196 Gene_expression of Cryab 17 0.64 22.5 0.38
75 INT127540 Gene_expression of Cryge 1 0.01 0.35 0.38
76 INT124634 Binding of MIP 2 0.35 0.46 0.31
77 INT153017 Positive_regulation of nct 1 0.21 0.6 0.31
78 INT133792 Phosphorylation of Vim 2 0.32 1.34 0.3
79 INT155476 Regulation of Binding of Vim 2 0.61 0.73 0.29
80 INT233863 Protein_catabolism of Vim 1 0.07 0.81 0.25
81 INT268762 Positive_regulation of Localization of Mip 1 0.49 0.83 0.23
82 INT229471 Regulation of Vim 4 0.28 0.86 0.22
83 INT246444 Negative_regulation of nct 1 0.20 0 0.22
84 INT183186 Regulation of Mip 4 0.26 1.26 0.2
85 INT268749 Regulation of Gene_expression of Mip 1 0.44 0.41 0.2
86 INT92374 Protein_catabolism of Vim 1 0.76 0.46 0.19
87 INT144013 Negative_regulation of Gene_expression of Hspb6 1 0.43 0.53 0.18
88 INT268758 Regulation of Positive_regulation of Mip 1 0.44 0.83 0.18
89 INT267193 Positive_regulation of Gene_expression of Cryab 6 0.41 5.71 0.17
90 INT268756 Negative_regulation of Positive_regulation of Mip 1 0.41 0.83 0.17
91 INT285900 Positive_regulation of Localization of MIP 1 0.49 1.09 0.17
92 INT122708 Localization of Mip 2 0.61 0.17 0.16
93 INT144009 Negative_regulation of Hspb6 3 0.43 0.46 0.15
94 INT288271 Transcription of CRYGD 1 0.17 0.53 0.14
95 INT246443 Localization of nct 1 0.35 0.07 0.14
96 INT267198 Positive_regulation of Cryab 1 0.46 6.69 0.13
97 INT229475 Negative_regulation of Vim 5 0.37 0.81 0.12
98 INT182694 Regulation of Gene_expression of Vim 2 0.24 1.01 0.12
99 INT101051 Regulation of Localization of Mip 1 0.19 0.09 0.11
100 INT229458 Negative_regulation of Gene_expression of Vim 6 0.36 0.45 0.09
101 INT268748 Phosphorylation of Mip 1 0.79 0.08 0.08
102 INT107387 Positive_regulation of Positive_regulation of Vim 1 0.25 0.69 0.08
103 INT140736 Binding of nct 2 0.18 0.3 0.07
104 INT228669 Positive_regulation of Localization of Vim 1 0.12 0.34 0.07
105 INT49625 Negative_regulation of Positive_regulation of Vim 1 0.22 1.33 0.07
106 INT144007 Localization of Hspb6 1 0.81 0.19 0.06
107 INT144006 Negative_regulation of Localization of Hspb6 1 0.59 0.19 0.06
108 INT243717 Positive_regulation of Phosphorylation of Vim 1 0.22 0.47 0.04
109 INT270865 Positive_regulation of Transcription of Vim 1 0.21 0.16 0.04
110 INT243716 Phosphorylation of Vim 1 0.26 0.46 0.04
111 INT150557 Regulation of nct 3 0.32 0 0
112 INT206486 Transcription of Vim 2 0.56 0.06 0
113 INT267203 Negative_regulation of Cryab 2 0.29 3.98 0
114 INT276270 Positive_regulation of Binding of MIP 1 0.16 0 0
115 INT225968 Regulation of Negative_regulation of Hspb6 1 0.12 0 0
116 INT340876 Positive_regulation of Negative_regulation of Cryab 1 0.20 0.62 0
117 INT299204 Transcription of Mip 1 0.21 0.62 0
118 INT267200 Regulation of Gene_expression of Cryab 1 0.30 1.27 0
119 INT144012 Positive_regulation of Hspb6 1 0.70 0.07 0
120 INT309967 Positive_regulation of Binding of Vim 1 0.13 0 0
121 INT63498 Protein_catabolism of CRYGD 1 0.30 0.41 0
122 INT144011 Positive_regulation of Gene_expression of Hspb6 1 0.50 0.07 0
123 INT340951 Negative_regulation of Localization of Vim 1 0.10 0 0
124 INT283676 Regulation of Cryab 1 0.09 0.82 0
125 INT340976 Negative_regulation of Negative_regulation of Vim 1 0.10 0 0
126 INT229480 Negative_regulation of Positive_regulation of Vim 1 0.27 0.09 0
127 INT267184 Negative_regulation of Gene_expression of Cryab 1 0.29 1.5 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox