GO:0005223

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Name intracellular cGMP activated cation channel activity
Categary Function
Go Slim No
Go Link GO:0005223
Unique Molecular Interactions 13
Total Molecular Interactions 15
Total Single Events 305
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for intracellular cGMP activated cation channel activity. They are ordered first by their pain relevance and then by number of times they were reported for intracellular cGMP activated cation channel activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT342165 Binding of Aqp1 and Nav1 1 0.25 0.57 1.25
2 INT309157 Aqp1 Positive_regulation of Bdnf 1 0.00 0.74 0.42
3 INT139778 Binding of AQP1 and GBE1 1 0.00 0.22 0.3
4 INT58305 AQP1 Regulation of Localization of TNF 1 0.10 0.16 0.22
5 INT58303 AQP1 Regulation of Gene_expression of IL1B 1 0.10 0.16 0.22
6 INT342163 Nkx2-1 Regulation of Gene_expression of Aqp1 1 0.06 0.51 0.2
7 INT85333 Aqp1 Positive_regulation of Negative_regulation of Tgfb1 1 0.25 0.67 0.15
8 INT327829 Aqp1 Regulation of Binding of Csf2 1 0.11 1 0.14
9 INT79900 NFE2L2 Positive_regulation of Gene_expression of AQP1 1 0.03 0 0
10 INT262498 Binding of Aqp1 and Cav1 1 0.03 0.56 0
11 INT98626 Aqp1 Positive_regulation of Aqp4 1 0.52 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for intracellular cGMP activated cation channel activity. They are ordered first by their pain relevance and then by number of times they were reported in intracellular cGMP activated cation channel activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT104567 Gene_expression of Aqp1 47 0.78 44.84 28.68
2 INT156134 Regulation of Gene_expression of Aqp1 5 0.59 7.2 5.3
3 INT85328 Negative_regulation of Aqp1 5 0.54 6.02 4.94
4 INT79902 Gene_expression of AQP1 33 0.78 24.72 4.55
5 INT85326 Positive_regulation of Aqp1 7 0.65 5.9 3.71
6 INT104570 Localization of Aqp1 8 0.77 5.83 3.51
7 INT2611 Negative_regulation of AQP1 17 0.39 10.04 2.15
8 INT141721 Binding of Aqp1 5 0.37 1.77 2.15
9 INT203308 Regulation of Aqp1 4 0.48 2.59 2.13
10 INT211054 Positive_regulation of AQP1 3 0.33 4.53 1.41
11 INT327824 Positive_regulation of Gene_expression of Aqp1 4 0.67 5.4 1.37
12 INT73553 Gene_expression of Aqp1 23 0.67 4.65 1.34
13 INT166889 Positive_regulation of Gene_expression of AQP1 10 0.70 6.43 0.99
14 INT183362 Regulation of AQP1 3 0.23 1.49 0.92
15 INT139780 Binding of AQP1 7 0.32 4.62 0.54
16 INT19592 Localization of AQP1 4 0.81 1.09 0.44
17 INT327786 Negative_regulation of Gene_expression of AQP1 3 0.29 4.21 0.44
18 INT203374 Positive_regulation of Regulation of Aqp1 2 0.36 0.91 0.37
19 INT293551 Regulation of Positive_regulation of Aqp1 1 0.13 0 0.31
20 INT104568 Negative_regulation of Localization of Aqp1 1 0.36 2.47 0.2
21 INT215814 Negative_regulation of Gene_expression of Aqp1 2 0.31 0.25 0.17
22 INT98625 Regulation of Aqp1 1 0.27 0.1 0.17
23 INT215820 Negative_regulation of Aqp1 3 0.23 0.83 0.1
24 INT159343 Positive_regulation of Localization of AQP1 1 0.11 0 0.1
25 INT327827 Negative_regulation of Gene_expression of Aqp1 1 0.45 0.8 0.08
26 INT262510 Regulation of Gene_expression of Aqp1 1 0.33 1.18 0.07
27 INT262504 Positive_regulation of Aqp1 1 0.25 0.43 0
28 INT286264 Positive_regulation of Negative_regulation of AQP1 1 0.01 0.79 0
29 INT262513 Negative_regulation of Binding of Aqp1 1 0.23 0.64 0
30 INT262514 Binding of Aqp1 1 0.20 0.64 0
31 INT299193 Transcription of Aqp1 1 0.56 0.62 0
32 INT262511 Positive_regulation of Gene_expression of Aqp1 1 0.37 1.78 0
33 INT327782 Regulation of Gene_expression of AQP1 1 0.36 1.63 0
34 INT262512 Localization of Aqp1 1 0.40 0.7 0
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