GO:0005224

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Name ATP-binding and phosphorylation-dependent chloride channel activity
Categary Function
Go Slim No
Go Link GO:0005224
Unique Molecular Interactions 13
Total Molecular Interactions 15
Total Single Events 130
Pain Genes Associated 1

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for ATP-binding and phosphorylation-dependent chloride channel activity. They are ordered first by their pain relevance and then by number of times they were reported for ATP-binding and phosphorylation-dependent chloride channel activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT117482 CFTR Negative_regulation of THRB 1 0.01 0.15 0.51
2 INT341623 Binding of CFTR and CTRC 1 0.35 1.22 0.46
3 INT341624 Binding of CFTR and PRSS1 1 0.39 1.01 0.45
4 INT352547 Binding of CFTR and DMD 1 0.01 1.42 0.35
5 INT196695 Prkaca Positive_regulation of CFTR 1 0.46 0.13 0.27
6 INT274697 Binding of CFTR and Cftr 1 0.08 0.69 0.27
7 INT196635 CFTR Positive_regulation of Gene_expression of CCL5 1 0.07 0.44 0.21
8 INT196610 IFNG Negative_regulation of CFTR 1 0.17 0.21 0.19
9 INT267660 CFTR Regulation of Gene_expression of P2RX2 1 0.25 0.51 0.18
10 INT196606 IFNG Positive_regulation of CFTR 1 0.16 0.45 0.16
11 INT196608 TNF Negative_regulation of CFTR 1 0.16 0.11 0.14
12 INT196639 Negative_regulation of NA Negative_regulation of Transcription of CFTR 1 0.02 0.63 0.03
13 INT213585 Binding of CFTR and FLNA 1 0.14 0.11 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for ATP-binding and phosphorylation-dependent chloride channel activity. They are ordered first by their pain relevance and then by number of times they were reported in ATP-binding and phosphorylation-dependent chloride channel activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT138802 Gene_expression of CFTR 36 0.70 18.8 7.02
2 INT151102 Positive_regulation of CFTR 22 0.61 15.27 5.12
3 INT169756 Binding of CFTR 9 0.35 9.65 4.55
4 INT151099 Negative_regulation of CFTR 12 0.59 10.28 3.79
5 INT166710 Positive_regulation of Gene_expression of CFTR 9 0.46 3.72 2.03
6 INT151101 Regulation of CFTR 4 0.62 3.69 1.89
7 INT196675 Localization of CFTR 4 0.64 1.95 1.19
8 INT61290 Regulation of Phosphorylation of CFTR 1 0.44 0.25 0.81
9 INT61291 Phosphorylation of CFTR 1 0.80 0.25 0.8
10 INT196682 Negative_regulation of Gene_expression of CFTR 6 0.34 1.96 0.73
11 INT151100 Negative_regulation of Positive_regulation of CFTR 1 0.43 1.11 0.73
12 INT151098 Positive_regulation of Positive_regulation of CFTR 2 0.50 0.9 0.63
13 INT267666 Regulation of Localization of CFTR 1 0.22 0.39 0.3
14 INT120959 Protein_catabolism of CFTR 1 0.03 0.14 0.28
15 INT196688 Positive_regulation of Binding of CFTR 1 0.26 0.33 0.24
16 INT196681 Negative_regulation of Localization of CFTR 1 0.34 0.18 0.15
17 INT196672 Positive_regulation of Localization of CFTR 1 0.41 0 0.1
18 INT196673 Regulation of Gene_expression of CFTR 1 0.36 0.62 0.08
19 INT196683 Negative_regulation of Transcription of CFTR 1 0.22 0.61 0.03
20 INT196685 Transcription of CFTR 1 0.37 0.6 0.03
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