GO:0005230

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Name extracellular ligand-gated ion channel activity
Categary Function
Go Slim No
Go Link GO:0005230
Unique Molecular Interactions 119
Total Molecular Interactions 140
Total Single Events 1628
Pain Genes Associated 25

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for extracellular ligand-gated ion channel activity. They are ordered first by their pain relevance and then by number of times they were reported for extracellular ligand-gated ion channel activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT135867 Zfp821 Positive_regulation of Positive_regulation of Chrne 1 0.01 0 2.44
2 INT179445 Vta1 Positive_regulation of Gabrd 1 0.09 0 1.98
3 INT112033 Gabrb3 Positive_regulation of Plcg1 1 0.05 0.18 1.49
4 INT112034 Gabrb3 Positive_regulation of Pik3r1 1 0.08 0.18 1.48
5 INT14827 Binding of Gabrd and Pag1 1 0.07 0.95 1.33
6 INT124435 Gene_expression of Chrna9 Positive_regulation of Phosphorylation of Creb1 1 0.11 0.6 1.17
7 INT123260 Binding of Gabrg2 and Serpini1 1 0.02 0.63 1.16
8 INT215648 Binding of Adora1 and Gabrd 1 0.03 0.06 1.16
9 INT123261 Gabrg2 Regulation of Serpini1 1 0.01 0.63 1.16
10 INT60584 Positive_regulation of Htr3a Positive_regulation of Localization of Cck 1 0.52 0.43 1.09
11 INT53847 Pag1 Regulation of Gabrd 1 0.01 1 1.08
12 INT53842 Abat Regulation of Gabrd 1 0.04 1 1.08
13 INT60794 Binding of TREH and Chrna9 1 0.00 0 1.04
14 INT60948 Ltp Negative_regulation of Negative_regulation of Gabrd 1 0.02 0.07 1.03
15 INT131173 Chrna7 Positive_regulation of Localization of Abat 1 0.10 0 1.01
16 INT81127 Binding of Gabrd and Abat 3 0.25 0 0.96
17 INT292988 Negative_regulation of SGCG Positive_regulation of GABRB3 1 0.01 0.3 0.89
18 INT310348 Binding of Tspo and Gabrd 1 0.00 0.43 0.88
19 INT292990 SGCG Positive_regulation of Gene_expression of GABRB3 1 0.01 0.29 0.87
20 INT292989 SGCG Positive_regulation of GABRB3 1 0.01 0.29 0.87
21 INT271511 Binding of Phb2 and Glrb 1 0.04 1.7 0.84
22 INT13428 Gabrd Regulation of Localization of Sstr2 1 0.31 0 0.79
23 INT23681 Negative_regulation of Binding of Stx3 and Chrna7 1 0.00 0 0.75
24 INT23680 Binding of Stx3 and Chrna7 1 0.00 0 0.75
25 INT19577 Gabrg1 Negative_regulation of Got1 1 0.04 0.16 0.74
26 INT235604 Binding of Htr1a and Htr3a 1 0.01 0 0.74
27 INT43662 Negative_regulation of Binding of Chrna7 and Rac1 1 0.01 0 0.73
28 INT43663 Binding of Chrna7 and Rac2 1 0.01 0 0.72
29 INT43661 Binding of Chrna7 and Rac1 1 0.01 0 0.72
30 INT14196 Glra2 Positive_regulation of Localization of Gh1 1 0.06 0 0.71
31 INT81769 Binding of Chrna4 and Neurod1 1 0.35 0.07 0.69
32 INT54155 Positive_regulation of Glra2 Positive_regulation of Localization of Gnrhr 1 0.02 0 0.63
33 INT343365 Acsf2 Negative_regulation of Gabrd 1 0.04 0 0.61
34 INT23679 Chrna7 Regulation of Binding of Stx3 1 0.00 0 0.56
35 INT60793 Negative_regulation of Binding of TREH and Chrna9 1 0.00 0 0.53
36 INT205733 Gphn Regulation of Gene_expression of Gabrd 1 0.03 0.18 0.51
37 INT167484 Binding of CHRNE and GGNBP2 1 0.02 0 0.5
38 INT146306 Binding of Chrna9 and Myo5c 1 0.01 0.27 0.48
39 INT88080 Binding of Chrna4 and Psmb6 1 0.03 0.56 0.46
40 INT83111 LIAS Negative_regulation of Binding of Chrna7 1 0.02 0 0.45
41 INT148930 Rac1 Regulation of Chrna7 1 0.13 0.6 0.44
42 INT5531 Binding of Acot1 and Chrna2 1 0.12 0 0.42
43 INT67633 Binding of DST and Gabrd 1 0.03 0 0.41
44 INT274781 Agrn Positive_regulation of Chrna2 1 0.08 0.18 0.41
45 INT103346 Abat Positive_regulation of Gabrd 1 0.20 0.08 0.4
46 INT85037 Binding of Cct2 and Chrna3 1 0.00 0.15 0.38
47 INT46788 Chrna7 Positive_regulation of G6pd 1 0.50 0 0.33
48 INT330794 Positive_regulation of Gabrd Positive_regulation of Localization of Bdnf 1 0.02 0.78 0.33
49 INT235884 Htr3a Regulation of Nr3c1 1 0.00 0.63 0.32
50 INT281797 Positive_regulation of Chrna4 Positive_regulation of Gene_expression of VEGFA 1 0.01 0.43 0.3
51 INT89013 Positive_regulation of Gabrd Positive_regulation of Pomc 1 0.21 0.18 0.29
52 INT159179 Mmp3 Regulation of Chrng 1 0.01 0.32 0.29
53 INT59682 Hps6 Positive_regulation of Binding of Chrna7 1 0.02 0 0.29
54 INT182347 Binding of Glrb and Cd163 1 0.24 0.98 0.28
55 INT126942 Binding of PKD2 and ZACN 1 0.00 1.38 0.28
56 INT244034 Binding of Gabrg2 and Ubqln1 1 0.01 0.09 0.26
57 INT54460 Binding of Abt1 and Chrna9 1 0.03 0.31 0.26
58 INT59683 Binding of Chrna7 and Evi2a 1 0.03 0 0.25
59 INT231797 Glrb Regulation of Negative_regulation of TNF 1 0.02 1.49 0.25
60 INT143972 Chrna7 Negative_regulation of Gene_expression of Trpv1 1 0.01 0.18 0.24
61 INT281798 CFD Regulation of Positive_regulation of Chrna4 1 0.01 0.24 0.24
62 INT244047 Binding of Gabrg2 and Myoz1 1 0.00 0.19 0.23
63 INT356231 Binding of Gabrb3 and Gad1 1 0.32 1.25 0.23
64 INT73969 Positive_regulation of Gabbr1 Regulation of Gabrd 1 0.01 0 0.23
65 INT191480 Htr3a Positive_regulation of Ca2 1 0.02 0.12 0.23
66 INT97868 Binding of Chrna2 and Regulation of Acot1 1 0.09 0 0.23
67 INT115352 Htr3a Positive_regulation of Gene_expression of Fos 1 0.54 0 0.22
68 INT143974 Chrna7 Positive_regulation of Vti1b 1 0.17 0.16 0.2
69 INT287014 Gabrd Regulation of Ptn 1 0.10 0 0.18
70 INT47426 Chrna7 Positive_regulation of Localization of Ldha 1 0.05 0 0.18
71 INT47427 Chrna7 Positive_regulation of Ldha 1 0.05 0 0.18
72 INT244038 Binding of Gabrg2 and Gabarap 1 0.08 0.24 0.18
73 INT261628 Binding of CHRNA3 and MAOA 1 0.22 1.61 0.17
74 INT261626 Binding of CHRNA5 and MAOA 1 0.22 1.6 0.17
75 INT101725 Binding of ITGA4 and Chrna7 1 0.00 0 0.16
76 INT340111 Chrna7 Regulation of CYSLTR1 1 0.00 0.25 0.15
77 INT60944 Htr3a Regulation of Positive_regulation of Fos 1 0.49 0.27 0.14
78 INT52294 Binding of Htr3a and Tcra-V11.1 1 0.27 0.37 0.14
79 INT156057 UMOD Regulation of GABRG3 1 0.01 0.54 0.14
80 INT126943 Binding of Pkd1 and ZACN 1 0.00 0.69 0.14
81 INT132253 Tm2d1 Regulation of Chrna9 1 0.02 0.09 0.14
82 INT75791 Positive_regulation of Htr3a Regulation of Acot1 1 0.23 0.12 0.14
83 INT271513 Binding of Glrb and Spha2 1 0.16 0.18 0.13
84 INT91119 ecs Regulation of Glra2 1 0.02 0.62 0.13
85 INT328143 Gabrb3 Positive_regulation of Ube3a 1 0.56 0.99 0.11
86 INT328146 Gabrb3 Negative_regulation of Ube3a 1 0.48 0.99 0.11
87 INT207683 Chrnb4 Positive_regulation of Htr3b 1 0.26 0.31 0.1
88 INT139558 Chrna4 Regulation of Neurod1 1 0.17 0 0.1
89 INT153026 Binding of HTR3A and INSRR 1 0.13 0.29 0.1
90 INT207682 Chrnb4 Positive_regulation of Hcn4 1 0.35 0.29 0.1
91 INT207681 Chrnb4 Positive_regulation of Scn2b 1 0.02 0.32 0.1
92 INT153027 Binding of HTR3A and KCNMA1 1 0.18 0.29 0.1
93 INT139557 Chrna4 Regulation of Gene_expression of Neurod1 1 0.17 0 0.1
94 INT207684 Chrnb4 Positive_regulation of Htr3a 1 0.22 0.3 0.1
95 INT73968 Gabbr1 Regulation of Gabrd 1 0.01 0 0.09
96 INT5529 Acot1 Positive_regulation of Chrna2 1 0.17 0 0.09
97 INT261625 Binding of CHRNA3 and CPD 1 0.07 0.35 0.08
98 INT220697 Binding of CHRNE and DBP 1 0.02 1.15 0.08
99 INT171709 Rac1 Negative_regulation of Localization of Chrna7 1 0.04 0.75 0.08
100 INT273947 Binding of Gabra1 and Mrvi1 1 0.00 0.94 0.07
101 INT5530 Positive_regulation of Binding of Acot1 and Chrna2 1 0.15 0 0.07
102 INT273937 Binding of Crem and Gabra1 1 0.30 0.94 0.07
103 INT220698 Binding of CHRNE and SFTPA1 1 0.01 0.75 0.06
104 INT271512 Binding of Glrb and Traf1 1 0.09 0.1 0.05
105 INT244048 Binding of Gabrg2 and Gabarapl1 1 0.02 0.19 0.05
106 INT271510 Binding of Glrb and rs 1 0.00 0.26 0.05
107 INT244031 Binding of Gabrg2 and Nsf 1 0.04 0.19 0.05
108 INT352062 Binding of SV2A and Chrna7 1 0.00 0.7 0.04
109 INT126110 Chrng Positive_regulation of Chrm1 1 0.00 0.1 0
110 INT126111 Chrm1 Positive_regulation of Chrng 1 0.00 0.1 0
111 INT348593 ZACN Regulation of Positive_regulation of PPARG 1 0.14 0.41 0
112 INT328141 Binding of Chrne and Gabrb3 1 0.41 0.08 0
113 INT312646 Agrn Positive_regulation of Phosphorylation of CHRNE 1 0.02 0.38 0
114 INT348595 Binding of PPARG and ZACN 1 0.07 0.38 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for extracellular ligand-gated ion channel activity. They are ordered first by their pain relevance and then by number of times they were reported in extracellular ligand-gated ion channel activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT23330 Binding of Chrna7 79 0.48 10.06 35.5
2 INT6943 Positive_regulation of Gabrd 71 0.70 17.36 35.25
3 INT11077 Positive_regulation of Htr3a 63 0.67 15.61 22.7
4 INT51801 Gene_expression of Gabrd 64 0.72 19.17 22.61
5 INT9230 Gene_expression of Htr3a 43 0.78 10.54 18.81
6 INT11524 Negative_regulation of Gabrd 39 0.58 6.25 18.8
7 INT6807 Regulation of Gabrd 39 0.62 9.22 18.74
8 INT12269 Gene_expression of Chrna9 39 0.73 6.98 18.44
9 INT21132 Gene_expression of GABRB3 36 0.33 11.32 17.61
10 INT9069 Regulation of Htr3a 29 0.60 6.18 16.55
11 INT9231 Binding of Htr3a 27 0.47 7.29 13.04
12 INT12369 Negative_regulation of Htr3a 28 0.59 8.78 12.62
13 INT12444 Binding of Gabrd 26 0.48 4.7 11.23
14 INT23675 Negative_regulation of Binding of Chrna7 18 0.37 0.5 10.74
15 INT65009 Gene_expression of HTR3A 29 0.75 8.51 10.59
16 INT23676 Gene_expression of Chrna7 47 0.75 23.66 9.51
17 INT49315 Localization of Gabrd 17 0.63 2.32 7.95
18 INT9966 Localization of Htr3a 14 0.80 2.28 7.92
19 INT59333 Positive_regulation of Chrna9 14 0.64 3.23 7.64
20 INT16268 Binding of HTR3A 15 0.47 7.38 7.18
21 INT88079 Gene_expression of Chrna4 20 0.76 8.52 6.98
22 INT9289 Gene_expression of Htr3a 15 0.75 4.43 6.69
23 INT539 Negative_regulation of Chrna7 14 0.42 4.59 6.42
24 INT16568 Positive_regulation of HTR3A 14 0.67 4.82 6.01
25 INT75682 Regulation of Chrna7 14 0.45 10.24 5.25
26 INT182338 Gene_expression of Glrb 11 0.51 14.26 5.1
27 INT23126 Regulation of HTR3A 10 0.60 5.42 4.81
28 INT59331 Positive_regulation of Gene_expression of Chrna9 6 0.62 1.91 4.63
29 INT6941 Positive_regulation of Positive_regulation of Gabrd 6 0.50 1.29 4.6
30 INT51072 Positive_regulation of Positive_regulation of Htr3a 10 0.49 1.84 4.53
31 INT16569 Negative_regulation of HTR3A 14 0.57 6.91 4.42
32 INT25468 Regulation of Htr3a 7 0.60 0.61 4.3
33 INT70739 Gene_expression of Gabrg2 11 0.75 4.15 4.18
34 INT5527 Binding of Chrna2 11 0.47 1.42 4.01
35 INT60789 Negative_regulation of Chrna9 9 0.34 0.91 3.95
36 INT4649 Positive_regulation of Chrna7 17 0.50 5.48 3.92
37 INT183560 Binding of GABRB3 12 0.23 2.59 3.77
38 INT65551 Transcription of Htr3a 5 0.69 1.52 3.74
39 INT54458 Binding of Chrna9 10 0.36 0.88 3.57
40 INT68791 Positive_regulation of Gene_expression of Gabrd 10 0.47 2.89 3.48
41 INT59334 Regulation of Chrna9 6 0.44 0.62 3.26
42 INT137049 Positive_regulation of Glrb 7 0.46 9.24 3.22
43 INT12273 Regulation of Chrna2 8 0.59 0.4 3.21
44 INT78189 Positive_regulation of Htr3a 6 0.67 0.78 3.14
45 INT261712 Regulation of GABRB3 6 0.09 3.03 3.14
46 INT9229 Negative_regulation of Gene_expression of Htr3a 5 0.41 0.83 3.13
47 INT244388 Regulation of Gene_expression of Gabrd 8 0.38 3.27 3.08
48 INT12270 Gene_expression of Chrna2 11 0.67 5.47 3.06
49 INT70738 Negative_regulation of Gabrg2 7 0.57 4 2.96
50 INT55824 Negative_regulation of Positive_regulation of Gabrd 5 0.59 1.56 2.88
51 INT20934 Binding of Htr3a 4 0.47 1.03 2.86
52 INT163528 Gene_expression of Gabra1 3 0.74 0.75 2.73
53 INT292993 Positive_regulation of Gene_expression of GABRB3 4 0.17 0.9 2.63
54 INT39367 Negative_regulation of Chrna2 5 0.42 0.53 2.57
55 INT135866 Positive_regulation of Positive_regulation of Chrne 1 0.12 0 2.43
56 INT292992 Negative_regulation of Gene_expression of GABRB3 3 0.15 0.78 2.41
57 INT139556 Positive_regulation of Chrna4 10 0.25 4.52 2.36
58 INT135862 Positive_regulation of Chrne 1 0.17 0 2.36
59 INT74361 Negative_regulation of Gabrb3 4 0.58 0.73 2.28
60 INT21130 Positive_regulation of GABRB3 4 0.27 1.88 2.21
61 INT24196 Positive_regulation of Binding of Chrna7 8 0.45 0.79 2.13
62 INT25739 Negative_regulation of Chrng 8 0.50 1.34 2.11
63 INT123253 Localization of Chrna4 4 0.44 1.31 1.99
64 INT18332 Regulation of Glra2 3 0.25 0.13 1.87
65 INT47425 Localization of Chrna7 11 0.81 6.7 1.86
66 INT51190 Negative_regulation of Htr3a 3 0.58 0.41 1.79
67 INT182334 Binding of Glrb 3 0.28 4.81 1.71
68 INT215636 Regulation of Localization of Gabrd 2 0.18 0.18 1.71
69 INT25738 Positive_regulation of Chrng 7 0.43 0.99 1.69
70 INT86092 Localization of HTR3A 4 0.78 0.52 1.64
71 INT169387 Regulation of Gene_expression of Chrna7 4 0.36 2.19 1.63
72 INT167847 Positive_regulation of Gene_expression of Chrna7 7 0.49 3.02 1.57
73 INT26876 Positive_regulation of Glra2 3 0.50 0.09 1.55
74 INT13176 Positive_regulation of Binding of Gabrd 3 0.38 0.73 1.55
75 INT74360 Gene_expression of Gabrb3 2 0.77 3.85 1.49
76 INT135864 Gene_expression of Chrne 6 0.65 0.76 1.47
77 INT121605 Transcription of Gabrd 2 0.19 0.37 1.46
78 INT119789 Localization of Chrna9 4 0.20 0.32 1.44
79 INT131297 Positive_regulation of Gene_expression of HTR3A 3 0.49 0.34 1.4
80 INT52394 Negative_regulation of Positive_regulation of Htr3a 3 0.57 0.38 1.37
81 INT183557 Localization of GABRB3 3 0.46 1.01 1.34
82 INT137048 Regulation of Glrb 2 0.39 3.2 1.32
83 INT13530 Negative_regulation of GABRB3 4 0.17 1.48 1.31
84 INT22426 Positive_regulation of Regulation of Chrna2 2 0.48 0.33 1.31
85 INT28981 Binding of Htr3b 4 0.28 1.67 1.27
86 INT25741 Regulation of Chrng 4 0.52 0.89 1.22
87 INT81768 Negative_regulation of Chrna4 5 0.42 1.97 1.2
88 INT236435 Negative_regulation of Gene_expression of Gabrd 4 0.17 0.91 1.19
89 INT18724 Binding of Chrng 4 0.47 0.37 1.18
90 INT292991 Negative_regulation of Localization of GABRB3 2 0.13 0.44 1.18
91 INT95370 Phosphorylation of Gabrd 3 0.78 0.46 1.15
92 INT163527 Positive_regulation of Gene_expression of Gabra1 1 0.31 0.16 1.15
93 INT215642 Regulation of Negative_regulation of Gabrd 2 0.07 0 1.14
94 INT24197 Regulation of Binding of Chrna7 2 0.11 0 1.14
95 INT215638 Negative_regulation of Localization of Gabrd 2 0.36 0.36 1.12
96 INT54505 Binding of Gabra1 2 0.35 0.45 1.1
97 INT57773 Gene_expression of Chrng 4 0.08 0.23 0.99
98 INT84389 Transcription of HTR3A 2 0.69 0.3 0.94
99 INT95372 Regulation of Phosphorylation of Gabrd 1 0.24 0.21 0.9
100 INT12271 Negative_regulation of Gene_expression of Chrna9 6 0.52 0.62 0.88
101 INT37107 Negative_regulation of CHRNE 4 0.43 2.25 0.87
102 INT37105 Binding of CHRNE 3 0.31 6.88 0.87
103 INT71405 Binding of Glra2 1 0.12 0.1 0.87
104 INT131757 Positive_regulation of Transcription of Gabrd 1 0.07 0.29 0.83
105 INT131759 Positive_regulation of Transcription of Htr3a 1 0.49 0.29 0.83
106 INT12272 Negative_regulation of Gene_expression of Chrna2 3 0.33 2.04 0.82
107 INT64681 Positive_regulation of Negative_regulation of Htr3a 2 0.49 0 0.82
108 INT318278 Regulation of Gene_expression of GABRB3 1 0.14 0.47 0.77
109 INT123254 Regulation of Chrna4 3 0.27 0.84 0.76
110 INT57842 Positive_regulation of Binding of Chrng 2 0.03 0.25 0.75
111 INT182344 Positive_regulation of Gene_expression of Glrb 1 0.38 2.92 0.74
112 INT214467 Regulation of Positive_regulation of Chrna9 1 0.06 0.64 0.7
113 INT85033 Positive_regulation of Chrna3 2 0.06 0.35 0.67
114 INT123251 Regulation of Gene_expression of Chrna4 2 0.27 0.36 0.67
115 INT133004 Gene_expression of Chrna3 2 0.58 0.63 0.66
116 INT28982 Regulation of Htr3b 1 0.13 0.26 0.65
117 INT264605 Negative_regulation of Binding of Htr3a 1 0.01 1.12 0.64
118 INT121610 Regulation of Transcription of Gabrd 1 0.10 0.08 0.64
119 INT182342 Regulation of Gene_expression of Glrb 1 0.34 1.12 0.63
120 INT54154 Positive_regulation of Positive_regulation of Glra2 1 0.03 0 0.63
121 INT344760 Gene_expression of GABRG3 1 0.36 0.41 0.62
122 INT99329 Binding of Chrna4 3 0.37 0.45 0.6
123 INT108911 Negative_regulation of Gene_expression of HTR3A 2 0.41 1.81 0.6
124 INT5525 Positive_regulation of Chrna2 3 0.66 0.44 0.59
125 INT19120 Positive_regulation of Binding of Htr3a 1 0.49 0.53 0.59
126 INT59332 Regulation of Gene_expression of Chrna9 3 0.55 0 0.58
127 INT123256 Regulation of Localization of Chrna4 1 0.27 0.28 0.58
128 INT74362 Regulation of Gabrb3 1 0.28 0 0.58
129 INT68027 Localization of Chrna2 1 0.44 0 0.57
130 INT282190 Regulation of Gene_expression of Htr3a 2 0.44 0.37 0.56
131 INT243940 Binding of Gabrg2 2 0.47 0.88 0.56
132 INT59335 Regulation of Gene_expression of Chrna2 3 0.30 0.81 0.55
133 INT39251 Negative_regulation of Gabrg1 1 0.06 0 0.53
134 INT163526 Regulation of Gene_expression of Gabra1 1 0.16 0.16 0.52
135 INT86339 Positive_regulation of Gabrb3 1 0.14 0.14 0.51
136 INT148391 Positive_regulation of Gabrg2 3 0.45 0.31 0.5
137 INT163185 Negative_regulation of Transcription of Chrng 1 0.39 0.62 0.49
138 INT163186 Transcription of Chrng 1 0.48 0.6 0.49
139 INT70517 Regulation of Binding of Htr3a 1 0.60 0 0.48
140 INT245016 Transcription of GABRB3 1 0.17 0 0.47
141 INT119609 Regulation of CHRNE 1 0.05 0.36 0.46
142 INT292608 Positive_regulation of Regulation of GABRB3 1 0.05 1.58 0.45
143 INT57772 Negative_regulation of Gene_expression of Chrng 1 0.04 0 0.44
144 INT57774 Negative_regulation of Negative_regulation of Chrng 1 0.04 0 0.44
145 INT281775 Regulation of Positive_regulation of Chrna4 1 0.02 0.98 0.41
146 INT161878 Negative_regulation of Gene_expression of Gabrg2 2 0.57 0.75 0.4
147 INT86093 Positive_regulation of Localization of HTR3A 1 0.67 0.08 0.4
148 INT60790 Positive_regulation of Negative_regulation of Chrna9 1 0.03 0 0.37
149 INT169388 Transcription of Chrna7 2 0.69 0.27 0.36
150 INT318270 Positive_regulation of Negative_regulation of GABRB3 1 0.11 0.09 0.36
151 INT169386 Regulation of Transcription of Chrna7 1 0.45 0.05 0.36
152 INT215151 Localization of Htr3a 1 0.61 0.69 0.36
153 INT119788 Positive_regulation of Localization of Chrna9 1 0.13 0 0.35
154 INT25740 Positive_regulation of Negative_regulation of Chrng 1 0.35 0.24 0.35
155 INT18120 Localization of Glra2 1 0.21 0 0.33
156 INT94219 Regulation of Binding of Chrna9 1 0.09 0 0.32
157 INT162567 Gene_expression of Htr3b 1 0.52 0.47 0.32
158 INT70737 Transcription of Gabrg2 3 0.52 0.67 0.31
159 INT18725 Negative_regulation of Binding of Chrng 1 0.13 0 0.3
160 INT86094 Regulation of Localization of HTR3A 1 0.44 0.28 0.3
161 INT94220 Positive_regulation of Binding of Chrna9 1 0.13 0 0.27
162 INT328133 Localization of Gabrb3 1 0.75 1.35 0.27
163 INT220699 Positive_regulation of CHRNE 5 0.32 2.26 0.26
164 INT296168 Phosphorylation of Htr3a 1 0.06 0 0.26
165 INT120590 Transcription of Chrna9 3 0.39 0.48 0.25
166 INT318277 Phosphorylation of GABRB3 1 0.19 0.45 0.25
167 INT182333 Negative_regulation of Gene_expression of Glrb 1 0.28 1.04 0.25
168 INT247915 Regulation of Positive_regulation of Gabrg2 1 0.26 0.08 0.25
169 INT216403 Positive_regulation of Negative_regulation of Gabrd 1 0.20 0.47 0.24
170 INT334903 Positive_regulation of Localization of Chrna7 2 0.04 0.83 0.23
171 INT356219 Binding of Gabrb3 1 0.29 1.25 0.23
172 INT73451 Positive_regulation of Positive_regulation of Chrna2 1 0.48 0 0.22
173 INT260854 Negative_regulation of Binding of Gabrd 1 0.10 0.06 0.22
174 INT75790 Regulation of Positive_regulation of Htr3a 2 0.44 0.22 0.19
175 INT538 Protein_catabolism of Chrna7 2 0.57 1.01 0.19
176 INT95662 Binding of Chrna3 1 0.00 0.17 0.17
177 INT55396 Negative_regulation of Binding of Htr3a 1 0.57 0.16 0.17
178 INT146702 Binding of ZACN 1 0.30 0.42 0.17
179 INT318139 Regulation of Gene_expression of Gabrg2 1 0.44 0.87 0.16
180 INT328139 Negative_regulation of Gene_expression of Gabrb3 1 0.43 0.1 0.15
181 INT261645 Positive_regulation of CHRNA5 1 0.37 0.69 0.14
182 INT261639 Positive_regulation of CHRNA3 1 0.38 0.68 0.14
183 INT37103 Gene_expression of CHRNE 5 0.67 4.32 0.12
184 INT1796 Phosphorylation of Chrna7 1 0.82 0 0.12
185 INT43207 Regulation of Positive_regulation of Chrna7 1 0.01 0 0.11
186 INT139554 Positive_regulation of Gene_expression of Chrna4 2 0.25 0 0.1
187 INT139553 Transcription of Chrna4 1 0.27 0 0.1
188 INT137264 Regulation of ZACN 1 0.22 1.09 0.1
189 INT139555 Positive_regulation of Positive_regulation of Chrna4 1 0.25 0 0.1
190 INT136073 Regulation of Positive_regulation of Chrna2 1 0.26 0.35 0.1
191 INT261641 Localization of CHRNA5 1 0.64 0.91 0.09
192 INT261646 Localization of CHRNA3 1 0.65 0.91 0.09
193 INT257606 Regulation of Chrne 1 0.44 1.09 0.08
194 INT220702 Protein_catabolism of CHRNE 1 0.64 1.22 0.08
195 INT343361 Positive_regulation of Transcription of Chrna9 1 0.09 0 0.07
196 INT207668 Binding of Chrnb4 1 0.27 0 0.05
197 INT243921 Regulation of Gabrg2 1 0.08 0.18 0.03
198 INT162566 Positive_regulation of Htr3b 1 0.38 0 0
199 INT348614 Regulation of Gene_expression of ZACN 1 0.08 0.36 0
200 INT328126 Positive_regulation of Gene_expression of Gabrb3 1 0.50 1.08 0
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