GO:0005242

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Name inward rectifier potassium channel activity
Categary Function
Go Slim No
Go Link GO:0005242
Unique Molecular Interactions 35
Total Molecular Interactions 45
Total Single Events 631
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for inward rectifier potassium channel activity. They are ordered first by their pain relevance and then by number of times they were reported for inward rectifier potassium channel activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT198958 Cnr1 Positive_regulation of Kcnj9 1 0.00 0.15 2.24
2 INT350862 Hist1h1t Regulation of Kcnj5 1 0.02 1.35 1.22
3 INT136989 EGF Negative_regulation of Positive_regulation of KCNJ2 1 0.04 1.09 1.1
4 INT136988 EGF Negative_regulation of KCNJ2 1 0.04 1.09 1.04
5 INT215647 Adora1 Positive_regulation of Kcnj5 1 0.00 0 0.62
6 INT64776 Binding of Oprm1 and Kcnj3 1 0.38 0 0.6
7 INT350859 Hist1h1t Regulation of Gene_expression of Kcnj5 1 0.02 0.37 0.59
8 INT350861 Hist1h1t Positive_regulation of Gene_expression of Kcnj5 1 0.02 0.35 0.56
9 INT155898 Binding of KCNJ8 and MMD 1 0.09 0.39 0.53
10 INT271902 Binding of KCNK1 and Jun 1 0.12 0.08 0.53
11 INT85565 Oprd1 Regulation of KCNJ6 1 0.00 0 0.51
12 INT350860 Hist1h1t Positive_regulation of Kcnj5 1 0.02 0.54 0.5
13 INT153897 Binding of KCNJ3 and Snx27 1 0.03 0.28 0.5
14 INT53139 Binding of Htr1a and Kcnj3 1 0.37 0 0.42
15 INT215629 Binding of Kcnj5 and Fig4 1 0.00 0.37 0.39
16 INT343857 Binding of ABCC8 and LY96 1 0.02 0.96 0.34
17 INT153896 Snx27 Regulation of KCNJ3 1 0.04 0.17 0.33
18 INT215645 Binding of Adora1 and Kcnj5 1 0.00 0.08 0.29
19 INT343856 Binding of S100A9 and ABCC8 1 0.04 0.9 0.28
20 INT231206 Binding of KCNH2 and KCNQ1 2 0.22 1.04 0.24
21 INT210551 Binding of KCNH2 and KCNE2 1 0.08 0 0.19
22 INT153895 Regulation of Snx27 Regulation of KCNJ3 1 0.04 0.08 0.16
23 INT326605 Binding of HTR1A and KCNH2 1 0.00 0.45 0.14
24 INT268024 Binding of Abcc8 and Kcnj5 2 0.14 0 0.07
25 INT207824 KCNJ5 Regulation of Localization of INS 1 0.01 0 0.07
26 INT292816 Binding of KCNJ11 and FTO 1 0.46 0.49 0.05
27 INT321412 ABCC8 Positive_regulation of Gene_expression of SELE 1 0.00 1.18 0.03
28 INT353872 Binding of KCNH1 and KCNH2 1 0.25 0.98 0
29 INT262515 Positive_regulation of Kcnj6 Positive_regulation of Binding of Bcl2 1 0.00 0.48 0
30 INT268021 Pde5a Positive_regulation of Kcnj5 1 0.01 0 0
31 INT353871 Negative_regulation of Binding of KCNH1 and KCNH2 1 0.30 0.98 0
32 INT268022 Pde5a Positive_regulation of Gene_expression of Kcnj5 1 0.01 0 0
33 INT246649 Binding of Kcnj11 and Krt23 1 0.01 0.53 0
34 INT209951 Binding of KCNJ13 and SNRNP70 1 0.00 0 0
35 INT268051 FSCN1 Regulation of Gene_expression of Kcnj5 1 0.01 0.1 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for inward rectifier potassium channel activity. They are ordered first by their pain relevance and then by number of times they were reported in inward rectifier potassium channel activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT89657 Gene_expression of Kcnj9 24 0.77 15.15 18.86
2 INT49768 Positive_regulation of Kcnj5 58 0.41 11.89 16.02
3 INT90184 Gene_expression of KCNJ6 7 0.67 4.14 12.57
4 INT57882 Negative_regulation of Kcnj5 33 0.35 13.06 12.27
5 INT93129 Negative_regulation of KCNH2 42 0.54 9.63 10.85
6 INT128906 Gene_expression of Kcnj5 35 0.43 7.48 10.33
7 INT62997 Gene_expression of Kcnj6 17 0.77 2.16 9.44
8 INT86600 Gene_expression of KCNH2 37 0.78 14.88 6.14
9 INT85563 Positive_regulation of KCNJ6 6 0.50 0.4 5.89
10 INT90188 Positive_regulation of KCNJ3 7 0.67 0 5.84
11 INT90957 Positive_regulation of Kcnj9 6 0.69 2 4.79
12 INT281850 Binding of KCNJ6 1 0.37 0.93 4.57
13 INT52608 Gene_expression of Kcnj3 16 0.78 0.42 4.03
14 INT107415 Regulation of Kcnj9 6 0.62 1 3.87
15 INT66473 Negative_regulation of Kcnj6 6 0.50 1.26 3.87
16 INT268032 Regulation of Kcnj5 23 0.27 3.66 3.51
17 INT85564 Negative_regulation of KCNJ6 6 0.25 0 3.24
18 INT100743 Regulation of KCNH2 6 0.54 2.37 2.61
19 INT86602 Binding of KCNH2 14 0.36 4.65 2.58
20 INT62998 Regulation of Kcnj6 4 0.39 0.5 2.57
21 INT136993 Positive_regulation of KCNJ2 3 0.35 3.61 2.42
22 INT131831 Negative_regulation of Kcnj9 2 0.43 0.66 2.42
23 INT107414 Positive_regulation of Gene_expression of Kcnj9 1 0.50 2.61 2.34
24 INT229242 Positive_regulation of Gene_expression of KCNJ6 2 0.50 1.47 2.03
25 INT117396 Binding of Kcnj6 1 0.35 1.58 1.95
26 INT100742 Regulation of Gene_expression of KCNH2 1 0.62 0.57 1.83
27 INT281851 Positive_regulation of Binding of KCNJ6 1 0.50 0.4 1.82
28 INT105567 Negative_regulation of Positive_regulation of Kcnj9 2 0.42 0.31 1.78
29 INT168757 Binding of Kcnj5 3 0.16 0.53 1.77
30 INT66469 Negative_regulation of Gene_expression of Kcnj6 3 0.58 0.32 1.77
31 INT53134 Localization of Kcnj3 2 0.79 0 1.67
32 INT136990 Gene_expression of KCNJ2 4 0.27 2.03 1.5
33 INT126121 Transcription of Kcnj6 1 0.65 0 1.45
34 INT90186 Positive_regulation of Positive_regulation of KCNJ3 1 0.49 0 1.34
35 INT90189 Positive_regulation of Positive_regulation of KCNJ6 1 0.45 0 1.34
36 INT85562 Regulation of KCNJ6 2 0.45 0.27 1.32
37 INT107135 Positive_regulation of KCNJ5 4 0.09 2.78 1.3
38 INT90190 Gene_expression of KCNJ3 3 0.75 0 1.23
39 INT107133 Regulation of KCNJ5 6 0.05 1.26 1.1
40 INT136992 Phosphorylation of KCNJ2 1 0.07 1.07 1.08
41 INT136994 Transcription of KCNJ2 1 0.05 1.08 1.03
42 INT90187 Negative_regulation of KCNJ3 2 0.57 0.17 0.95
43 INT128907 Regulation of Gene_expression of Kcnj5 4 0.19 0.59 0.89
44 INT90185 Negative_regulation of Positive_regulation of KCNJ3 1 0.42 0 0.81
45 INT131837 Transcription of KCNK1 1 0.67 0.36 0.8
46 INT194343 Gene_expression of ABCC8 8 0.65 8.15 0.77
47 INT52607 Positive_regulation of Gene_expression of Kcnj3 2 0.40 0.17 0.68
48 INT64775 Binding of Kcnj3 1 0.32 0 0.65
49 INT126563 Negative_regulation of Positive_regulation of Kcnj5 2 0.19 0.63 0.63
50 INT101748 Localization of Kcnj5 3 0.20 0.73 0.62
51 INT128905 Positive_regulation of Gene_expression of Kcnj5 3 0.38 0.8 0.58
52 INT66470 Regulation of Gene_expression of Kcnj6 1 0.27 0 0.57
53 INT83814 Positive_regulation of Kcnj6 4 0.16 0.84 0.56
54 INT271899 Binding of KCNK1 1 0.11 0.08 0.53
55 INT86601 Positive_regulation of KCNH2 7 0.49 1.56 0.52
56 INT207828 Gene_expression of KCNJ5 9 0.58 0.14 0.51
57 INT155905 Localization of KCNJ8 1 0.73 0.49 0.51
58 INT101563 Transcription of Kcnj9 2 0.63 0.71 0.49
59 INT155907 Transcription of KCNJ8 1 0.69 0.48 0.48
60 INT153894 Regulation of KCNJ3 1 0.05 0.27 0.47
61 INT53133 Negative_regulation of Kcnj3 1 0.40 0 0.45
62 INT53138 Positive_regulation of Negative_regulation of Kcnj3 1 0.43 0 0.45
63 INT53136 Positive_regulation of Localization of Kcnj3 1 0.47 0 0.45
64 INT144263 Gene_expression of KCNK1 3 0.58 0.14 0.43
65 INT53137 Positive_regulation of Kcnj3 1 0.65 0 0.42
66 INT109960 Positive_regulation of ABCC8 4 0.49 1.74 0.36
67 INT221224 Gene_expression of KCNJ11 2 0.61 5.83 0.33
68 INT62438 Regulation of Kcnj3 2 0.27 0.07 0.3
69 INT207831 Localization of KCNJ5 1 0.07 0.09 0.3
70 INT126562 Positive_regulation of Positive_regulation of Kcnj5 2 0.22 0.17 0.28
71 INT297224 Negative_regulation of Negative_regulation of Kcnj5 1 0.11 0.74 0.27
72 INT297220 Transcription of Kcnj5 1 0.14 0.09 0.26
73 INT127711 Negative_regulation of Positive_regulation of Kcnj6 1 0.14 0.27 0.26
74 INT343893 Localization of ABCC8 1 0.13 0.94 0.26
75 INT281852 Transcription of KCNJ6 1 0.69 0 0.23
76 INT210568 Positive_regulation of Localization of KCNH2 1 0.38 0 0.21
77 INT207827 Positive_regulation of Gene_expression of KCNJ5 1 0.04 0.08 0.21
78 INT195965 Localization of Kcnj9 1 0.64 0.18 0.21
79 INT210570 Localization of KCNH2 2 0.63 0.8 0.2
80 INT145918 Negative_regulation of Gene_expression of KCNJ2 1 0.01 0 0.19
81 INT145917 Negative_regulation of KCNJ2 1 0.01 0 0.19
82 INT294991 Negative_regulation of ABCC8 1 0.17 3.08 0.18
83 INT207826 Regulation of Gene_expression of KCNJ5 1 0.04 0 0.17
84 INT155908 Negative_regulation of KCNJ8 1 0.42 0.18 0.16
85 INT147341 Negative_regulation of Binding of KCNH2 1 0.39 0.59 0.15
86 INT323465 Regulation of Localization of Kcnj6 1 0.02 0.05 0.13
87 INT323474 Localization of Kcnj6 1 0.03 0.05 0.13
88 INT250219 Positive_regulation of KCNJ11 3 0.68 2.5 0.12
89 INT171668 Positive_regulation of Positive_regulation of KCNH2 1 0.08 0.46 0.11
90 INT207839 Negative_regulation of KCNJ5 1 0.03 0 0.11
91 INT62680 Binding of KCNJ5 2 0.12 1.03 0.1
92 INT297225 Negative_regulation of Localization of Kcnj5 1 0.11 0.58 0.09
93 INT58644 Negative_regulation of KCNJ11 1 0.24 0 0.08
94 INT207818 Positive_regulation of Kcnj11 2 0.48 1.67 0.07
95 INT93128 Regulation of Negative_regulation of KCNH2 1 0.31 0 0.07
96 INT294994 Negative_regulation of Gene_expression of ABCC8 1 0.12 1.28 0.07
97 INT207833 Negative_regulation of Localization of KCNJ5 1 0.03 0 0.07
98 INT185406 Regulation of ABCC8 2 0.13 2.21 0.05
99 INT210569 Negative_regulation of Gene_expression of KCNH2 2 0.41 0 0.03
100 INT207834 Negative_regulation of Localization of KCNJ11 1 0.41 0 0.03
101 INT207832 Localization of KCNJ11 1 0.73 0 0.03
102 INT221703 Positive_regulation of Gene_expression of KCNK1 1 0.26 0 0.03
103 INT268033 Regulation of Positive_regulation of Kcnj5 2 0.19 0 0
104 INT250220 Binding of ABCC8 1 0.37 1.02 0
105 INT150092 Binding of Kcnj9 1 0.48 0.05 0
106 INT294992 Positive_regulation of Gene_expression of ABCC8 1 0.14 0.29 0
107 INT268035 Negative_regulation of Gene_expression of Kcnj5 1 0.18 0.1 0
108 INT244609 Binding of KCNJ13 1 0.09 0 0
109 INT163305 Negative_regulation of KCNJ13 1 0.37 0 0
110 INT329212 Phosphorylation of KCNJ11 1 0.80 1.07 0
111 INT353880 Negative_regulation of Localization of KCNH2 1 0.36 0.8 0
112 INT142323 Negative_regulation of Negative_regulation of KCNH2 1 0.51 0 0
113 INT244604 Gene_expression of KCNJ13 1 0.15 0 0
114 INT339052 Binding of KCNJ11 1 0.34 1.16 0
115 INT268036 Regulation of Binding of Kcnj5 1 0.19 0 0
116 INT329213 Positive_regulation of Phosphorylation of KCNJ11 1 0.45 1.14 0
117 INT353885 Positive_regulation of Gene_expression of KCNH2 1 0.42 1.28 0
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