GO:0005245

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Name voltage-gated calcium channel activity
Categary Function
Go Slim No
Go Link GO:0005245
Unique Molecular Interactions 289
Total Molecular Interactions 403
Total Single Events 3112
Pain Genes Associated 24

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for voltage-gated calcium channel activity. They are ordered first by their pain relevance and then by number of times they were reported for voltage-gated calcium channel activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73
2 INT74840 Binding of Cacna1a and Cacna1a 5 0.00 4.24 2.36
3 INT122660 Binding of CACNA1A and DNAH8 2 0.28 2.68 2.08
4 INT355251 Cacna1a Regulation of Gene_expression of Gabrg1 1 0.01 0.06 1.86
5 INT355249 Cacna1a Regulation of Gene_expression of Ltp 1 0.04 0.06 1.86
6 INT355254 Ltp Regulation of Cacna1a 1 0.04 0 1.58
7 INT74843 Binding of Cacna1a and Ea2 3 0.13 3.29 1.55
8 INT355250 Ltp Regulation of Positive_regulation of Cacna1a 1 0.04 0 1.39
9 INT108727 Binding of ATP1A2 and CACNA1A 2 0.34 1.97 1.37
10 INT122659 Binding of CACNA1A and SAR1B 1 0.06 1.38 1.35
11 INT355253 Ltp Positive_regulation of Cacna1a 1 0.05 0 1.34
12 INT355252 Binding of Cacna1a and Cnr1 1 0.04 0 1.31
13 INT168866 Binding of RYR1 and Cd38 1 0.02 0.17 1.28
14 INT154203 Binding of Pick1 and Grm7 1 0.41 1.64 1.28
15 INT74841 Binding of Cacna1a and Ea2 2 0.01 2.33 1.27
16 INT169557 Cacna1h Positive_regulation of Mapk1 1 0.07 0.91 1.17
17 INT108729 Binding of CACNA1A and Cacna1a 3 0.13 1.21 0.95
18 INT13282 Fgf2 Regulation of Ngf 1 0.66 0.21 0.91
19 INT66334 Fgf2 Regulation of Fgf1 1 0.37 0.17 0.9
20 INT13280 Ngf Regulation of Fgf2 1 0.48 0.2 0.9
21 INT66333 Fgf2 Negative_regulation of Positive_regulation of Npy 1 0.20 0.17 0.85
22 INT183175 Binding of FGF2 and NUDT6 1 0.07 1.07 0.84
23 INT336835 Binding of CACNG6 and Aia1 1 0.01 3.41 0.75
24 INT123077 Cacna1c Negative_regulation of Gene_expression of Dbi 1 0.05 0.71 0.7
25 INT214410 Binding of ATP1A4 and CACNA1A 1 0.26 0.95 0.7
26 INT31416 Cacna1a Positive_regulation of Gene_expression of Gcg 1 0.03 0 0.65
27 INT224726 Negative_regulation of Binding of Fgf2 and Cia1 1 0.01 0.92 0.62
28 INT224727 Binding of Fgf2 and Cia1 1 0.01 0.91 0.61
29 INT339532 FGF2 Positive_regulation of YWHAZ 1 0.00 1.26 0.54
30 INT216941 P2rx7 Regulation of Ryr1 1 0.01 0.55 0.52
31 INT66336 Fgf2 Regulation of Gene_expression of Npy 1 0.12 0.09 0.5
32 INT244028 Positive_regulation of Binding of Cacnb3 and Tfap2a 1 0.01 0.24 0.49
33 INT244021 Positive_regulation of Binding of Cacnb3 and Prkaca 1 0.02 0.24 0.49
34 INT228449 PMAIP1 Negative_regulation of Fgf2 1 0.00 0.07 0.49
35 INT244036 Binding of Cacnb3 and Prkaca 1 0.01 0.24 0.49
36 INT244060 Binding of Cacnb3 and Tfap2a 1 0.00 0.24 0.49
37 INT354986 Cacna1a Regulation of Localization of Mpo 1 0.01 1.15 0.49
38 INT354981 Cacna1a Negative_regulation of Gene_expression of Nos2 1 0.01 0.99 0.45
39 INT66335 Fgf1 Regulation of Fgf2 1 0.10 0.08 0.45
40 INT296477 Binding of Cacng2 and Dlg4 1 0.04 0.22 0.42
41 INT155752 Binding of CACNA1A and ATCAY 1 0.04 0.86 0.42
42 INT160971 Gm2111 Positive_regulation of Grm7 1 0.01 0.16 0.41
43 INT13283 Egf Regulation of Fgf2 1 0.49 0.11 0.41
44 INT13284 Fgf2 Regulation of Egf 1 0.49 0.11 0.41
45 INT99122 Binding of Cacna2d3 and DLL1 1 0.02 0 0.41
46 INT354984 Binding of Cacna1a and Tnf 1 0.01 0.83 0.4
47 INT92690 Tgfb1 Positive_regulation of Transcription of Fgf2 1 0.32 1.8 0.4
48 INT149221 Binding of Ryr1 and Trpc3 5 0.40 0 0.37
49 INT158355 Cacna1a Regulation of Alox5 1 0.01 0.7 0.37
50 INT354985 Cacna1a Regulation of Nos2 1 0.01 0.73 0.34
51 INT354982 Cacna1a Regulation of Tnf 1 0.00 0.73 0.34
52 INT295755 Fgf2 Regulation of MMP9 1 0.07 0.99 0.33
53 INT101551 Binding of CACNA1A and CACNA1F 1 0.07 1.51 0.33
54 INT151258 Binding of Cacna1a and FCMTE1 1 0.00 0.57 0.3
55 INT77753 Abnormal Regulation of CACNA1S 1 0.00 0.78 0.28
56 INT56091 FGF2 Positive_regulation of Transcription of SERPINE1 1 0.43 0.41 0.28
57 INT126942 Binding of PKD2 and ZACN 1 0.00 1.38 0.28
58 INT349951 Grm7 Regulation of pcp 1 0.00 0.56 0.28
59 INT142003 Binding of Cacna1a and Etax2 1 0.00 1.02 0.26
60 INT296450 Cacng2 Regulation of Gria2 1 0.13 0.24 0.26
61 INT142004 Binding of Cacna1a and TGM6 1 0.00 1.02 0.26
62 INT346745 Binding of Cacng2 and Grip2 1 0.01 0 0.25
63 INT296470 Binding of Cacng2 and Myo18a 1 0.00 0.22 0.24
64 INT296467 Binding of Cacng2 and Gria1 1 0.12 0.25 0.23
65 INT296464 Binding of Cacng2 and Tinagl1 1 0.06 0.25 0.23
66 INT296474 Binding of Cacng2 and Gria2 1 0.18 0.26 0.23
67 INT339535 FGF2 Positive_regulation of Gene_expression of CYP4A11 1 0.00 0.55 0.22
68 INT283373 Pcbd1 Regulation of RYR1 1 0.00 1.45 0.21
69 INT289356 Binding of Akt1 and Fgf2 1 0.03 0.82 0.21
70 INT354519 Cacna1c Regulation of Mri1 1 0.00 1.15 0.21
71 INT174861 Binding of FGF2 and VEGFA 1 0.34 0.59 0.2
72 INT121807 CACNA1A Regulation of CAV2 1 0.01 0.25 0.2
73 INT92693 Tgfb1 Positive_regulation of Fgf2 1 0.32 0.9 0.2
74 INT126944 Binding of PKD2 and Pkd1 2 0.08 2.09 0.19
75 INT201212 FGF2 Regulation of FGFR1 2 0.09 1.01 0.18
76 INT337697 FGF2 Regulation of VEGFA 1 0.03 0.51 0.18
77 INT152024 Ptgs1 Regulation of Fgf2 1 0.04 0.9 0.17
78 INT224730 Fgf2 Positive_regulation of Gm2458 1 0.01 0.39 0.17
79 INT207784 Ap3d1 Regulation of CACNA1S 1 0.05 0.97 0.16
80 INT24667 Binding of COL7A1 and FGF2 1 0.13 0.25 0.16
81 INT296469 Gene_expression of Cacng2 Positive_regulation of Gria2 1 0.15 0 0.16
82 INT296461 Gene_expression of Cacng2 Positive_regulation of Rbm39 1 0.00 0 0.16
83 INT241967 Binding of Grm7 and Acpt 1 0.17 0 0.16
84 INT303866 Positive_regulation of NAA50 Negative_regulation of Gene_expression of CACNA1C 1 0.13 0.08 0.16
85 INT345999 Binding of Fgf2 and Gfap 1 0.37 0.09 0.16
86 INT71329 Cacna1a Regulation of Ea2 1 0.01 0.71 0.15
87 INT298717 Fgf2 Positive_regulation of Gene_expression of PDGFA 1 0.01 0.23 0.15
88 INT172903 Fgf2 Positive_regulation of Gene_expression of Tbxa2r 1 0.03 0.58 0.15
89 INT71328 Cacna1a Regulation of Atxn2 1 0.00 0.71 0.15
90 INT345996 Fgf2 Positive_regulation of Gene_expression of Gfap 1 0.71 0.13 0.15
91 INT244065 Negative_regulation of Bdnf Positive_regulation of Phosphorylation of Cacnb3 1 0.04 0.1 0.15
92 INT249849 Ufm1 Positive_regulation of Fgf2 1 0.01 0.56 0.14
93 INT278265 Binding of Fgf2 and Smcp 1 0.03 0.26 0.14
94 INT274472 IL12A Negative_regulation of Gene_expression of FGF2 1 0.02 0.36 0.14
95 INT274473 IL12A Regulation of Gene_expression of FGF2 1 0.02 0.36 0.14
96 INT315032 Binding of Cav1 and Ryr1 1 0.27 0.2 0.14
97 INT345998 Fgf2 Positive_regulation of Gfap 1 0.48 0.09 0.13
98 INT170991 FGF2 Positive_regulation of Gene_expression of TIMP1 1 0.01 0.72 0.13
99 INT207785 Binding of RYR1 and Ap3d1 1 0.06 3.24 0.13
100 INT300853 Ngf Positive_regulation of Fgf2 1 0.14 0.18 0.12
101 INT207776 Binding of FKBP1A and RYR1 1 0.05 0.59 0.12
102 INT300860 Bdnf Positive_regulation of Fgf2 1 0.08 0.18 0.12
103 INT351427 Binding of PIK3C3 and RYR1 1 0.00 0 0.11
104 INT296468 Cacng2 Regulation of Regulation of Gria2 1 0.10 0 0.11
105 INT149219 Binding of Ryr1 and Trpc1 1 0.35 0 0.11
106 INT351545 FGF2 Positive_regulation of CDH16 1 0.01 0.19 0.1
107 INT351546 FGF2 Positive_regulation of L1CAM 1 0.34 0.19 0.1
108 INT225740 RYR1 Positive_regulation of Binding of Entpd1 1 0.08 0.08 0.1
109 INT351543 FGF2 Positive_regulation of NCAM1 1 0.03 0.14 0.1
110 INT122546 FGF2 Regulation of Localization of IL6 1 0.55 0.1 0.1
111 INT120559 Binding of Cacna1a and FCMTE1 1 0.02 0.25 0.1
112 INT249848 Fgf2 Positive_regulation of Gene_expression of Nos3 1 0.33 0.44 0.1
113 INT122542 FGF2 Positive_regulation of Localization of IL6 1 0.62 0.09 0.09
114 INT117838 FGFR1 Regulation of FGF2 1 0.33 0.17 0.09
115 INT301921 UCK2 Regulation of Gene_expression of FGF2 1 0.01 1.22 0.08
116 INT196213 REST Regulation of Gene_expression of CACNA1A 1 0.46 0.08 0.08
117 INT222139 Binding of Egf and Fgf2 1 0.12 0 0.07
118 INT236531 Binding of Cacna1f and Flna 1 0.08 0 0.07
119 INT265983 Homer1 Regulation of Ryr1 1 0.37 0.15 0.07
120 INT111933 Cacna1c Positive_regulation of PENK 1 0.01 0 0.07
121 INT343479 Epo Positive_regulation of Fgf2 1 0.33 0.3 0.06
122 INT24666 Binding of EGF and FGF2 1 0.35 0 0.06
123 INT254463 Binding of Camk2a and Cacna1c 1 0.00 0.17 0.06
124 INT170517 Binding of Ryr1 and Qdpr 2 0.15 0.36 0.05
125 INT244041 Binding of Cacnb3 and Gabrg1 1 0.03 0 0.05
126 INT348690 Atp9a Positive_regulation of Gene_expression of Fgf2 1 0.00 0.21 0.05
127 INT295715 PTGER2 Regulation of Localization of FGF2 1 0.02 0.6 0.05
128 INT295723 VEGFA Regulation of Localization of FGF2 1 0.07 0.6 0.05
129 INT354983 Cacna1a Regulation of Mpo 1 0.02 0.41 0.04
130 INT185270 Binding of Fgf2 and Ifaprc2 1 0.08 0.4 0.04
131 INT253017 PTTG1IP Regulation of Regulation of Fgf2 1 0.03 0.49 0.04
132 INT354987 Cacna1a Regulation of Localization of LDHA 1 0.00 0.23 0.03
133 INT253010 Binding of PTTG1 and Fgf2 1 0.07 0.51 0.03
134 INT315034 Ass1 Positive_regulation of Cacna1f 1 0.00 0 0.03
135 INT329993 Binding of CACNA1C and KCNMA1 1 0.32 0.19 0
136 INT351155 AKT1 Positive_regulation of Positive_regulation of FGF2 1 0.03 0.81 0
137 INT260268 Binding of FGF2 and FGFR1 1 0.46 0.94 0
138 INT346742 Binding of Cacng2 and Dlg4 1 0.03 0 0
139 INT348687 Fgf2 Regulation of Gene_expression of Plau 1 0.14 0 0
140 INT348688 Fgf2 Regulation of Plau 1 0.14 0 0
141 INT196208 REST Regulation of CACNA1A 1 0.46 0.06 0
142 INT245078 FGF2 Positive_regulation of CXCR4 1 0.07 1.36 0
143 INT325589 Nppa Regulation of Cacna1c 1 0.05 0 0
144 INT196216 Binding of CACNA1A and REST 1 0.28 0 0
145 INT183090 Gene_expression of SULF1 Positive_regulation of Phosphorylation of FGF2 1 0.19 0.42 0
146 INT348693 Atp9a Positive_regulation of Fgf2 1 0.00 0.07 0
147 INT261963 Binding of Cacna1a and Tgm2 1 0.08 1.19 0
148 INT266704 Binding of RYR1 and TRDN 1 0.34 0 0
149 INT316647 Ryr1 Regulation of Qdpr 1 0.19 0.68 0
150 INT253021 PTTG1 Regulation of Gene_expression of Fgf2 1 0.04 0.35 0
151 INT183091 Binding of FGF2 and FGFR2 1 0.03 0.79 0
152 INT175076 Binding of Fgf2 and Klk1c9 1 0.02 0.38 0
153 INT261883 PKD2 Positive_regulation of Localization of Ca2 1 0.02 0.67 0
154 INT348689 Fgf2 Regulation of Map3k1 1 0.09 0 0
155 INT150378 Fgf2 Positive_regulation of Mcpt1 1 0.67 1.79 0
156 INT150379 Fgf2 Positive_regulation of Gene_expression of Mcpt1 1 0.45 0.89 0
157 INT183093 SULF1 Negative_regulation of Binding of FGF2 1 0.17 0.41 0
158 INT180856 FGF2 Positive_regulation of Transcription of MT1L 1 0.30 1.06 0
159 INT346746 Binding of Cacng2 and Gria2 1 0.21 0.18 0
160 INT250496 Gopc Regulation of Positive_regulation of Cacna1a 1 0.37 0 0
161 INT299130 Cxcl12 Positive_regulation of Gene_expression of Fgf2 1 0.15 0.38 0
162 INT122541 FGF2 Positive_regulation of Transcription of IL6 1 0.42 0 0
163 INT283372 Binding of RYR1 and Pcbd1 1 0.00 0.28 0
164 INT122544 FGF2 Positive_regulation of Positive_regulation of GRAP2 1 0.20 0 0
165 INT314986 Ins1 Negative_regulation of CACNA1S 1 0.00 0.08 0
166 INT241443 Binding of Tgtp1 and Cacna1d 1 0.00 0 0
167 INT315029 Binding of Calm3 and Cacna1f 1 0.04 0 0
168 INT336179 Binding of CACNA1F and DLST 1 0.01 1.6 0
169 INT249454 us Positive_regulation of Gene_expression of FGF2 1 0.01 0.13 0
170 INT342559 FGF2 Positive_regulation of MAPK1 1 0.08 1.22 0
171 INT279694 Hc Negative_regulation of Catsper1 1 0.05 0 0
172 INT122539 FGF2 Regulation of Transcription of IL6 1 0.24 0 0
173 INT299129 Cxcl12 Positive_regulation of Transcription of Fgf2 1 0.16 0.38 0
174 INT260266 Binding of FGF2 and FGFBP1 1 0.48 0.94 0
175 INT185268 Binding of Fgf2 and Sox1 1 0.19 0 0
176 INT122537 FGF2 Positive_regulation of Gene_expression of IL6 1 0.45 0 0
177 INT222481 Fgf2 Positive_regulation of Gene_expression of Prl 1 0.10 0 0
178 INT122536 FGF2 Positive_regulation of Positive_regulation of SGSM3 1 0.73 0 0
179 INT122540 FGF2 Positive_regulation of Binding of JUN 1 0.24 0 0
180 INT122543 FGF2 Positive_regulation of JUN 1 0.36 0 0
181 INT271027 Binding of RYR1 and Car2 1 0.03 0.46 0
182 INT122545 FGF2 Positive_regulation of Positive_regulation of MAPK3 1 0.53 0 0
183 INT315031 Binding of Cacna1f and Vsig2 1 0.02 0 0
184 INT266703 Binding of RYR1 and DIXDC1 1 0.26 0.1 0
185 INT342557 FGF2 Positive_regulation of MAPK3 1 0.03 1.21 0
186 INT296930 Casq1 Negative_regulation of RYR1 1 0.00 0.38 0
187 INT336829 RS1 Regulation of CACNG6 1 0.15 0.15 0
188 INT183089 Positive_regulation of Binding of FGF2 and FGFR2 1 0.04 0.4 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for voltage-gated calcium channel activity. They are ordered first by their pain relevance and then by number of times they were reported in voltage-gated calcium channel activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT66331 Gene_expression of Cacna1a 101 0.78 49.58 46.32
2 INT26698 Positive_regulation of Cacna1a 37 0.67 26.33 39.1
3 INT41487 Negative_regulation of Cacna1a 16 0.57 9.42 25.2
4 INT48144 Gene_expression of Fgf2 117 0.78 43 20.48
5 INT31136 Binding of Cacna1a 28 0.45 30.76 17.35
6 INT24670 Gene_expression of FGF2 121 0.78 85.64 15.12
7 INT61548 Positive_regulation of Fgf2 72 0.70 32.18 14.49
8 INT99116 Binding of Cacna2d3 15 0.48 7.33 13.58
9 INT30101 Regulation of Cacna1a 25 0.45 14.38 12.43
10 INT75765 Positive_regulation of Gene_expression of Cacna1a 17 0.70 17.51 10.91
11 INT68133 Localization of Fgf2 36 0.81 15.37 9.14
12 INT68267 Gene_expression of CACNA1A 22 0.75 11.39 8.65
13 INT92680 Gene_expression of Fgf2 59 0.77 28.11 8.12
14 INT73544 Gene_expression of Grm7 34 0.64 31.28 8.04
15 INT18393 Negative_regulation of Ryr1 15 0.43 3.63 7.57
16 INT91821 Binding of Cacna1a 16 0.48 13.1 6.37
17 INT64689 Positive_regulation of Gene_expression of Fgf2 30 0.70 12.05 6.2
18 INT92679 Positive_regulation of Fgf2 13 0.69 11.43 5.18
19 INT97905 Positive_regulation of FGF2 33 0.70 26.74 5.17
20 INT129508 Localization of Cacna1a 7 0.74 6.47 5.13
21 INT59555 Binding of RYR1 39 0.42 8.65 4.92
22 INT110796 Positive_regulation of Positive_regulation of Cacna1a 1 0.49 0.51 4.84
23 INT79682 Gene_expression of Grm7 6 0.75 4.74 4.5
24 INT82731 Transcription of Cacna1a 5 0.56 3.41 4.27
25 INT69781 Negative_regulation of FGF2 22 0.42 17.25 4.24
26 INT287526 Negative_regulation of Gene_expression of CACNA1A 1 0.42 4.25 3.81
27 INT79680 Binding of Grm7 6 0.47 2.83 3.58
28 INT18396 Positive_regulation of Ryr1 10 0.58 2.45 3.38
29 INT48122 Regulation of Cacna1h 5 0.42 3 3.37
30 INT53516 Binding of CACNA1A 9 0.47 6.86 3.36
31 INT167913 Gene_expression of CACNA1C 3 0.75 0.38 3.34
32 INT94045 Regulation of Cacna1a 5 0.42 3.56 3.33
33 INT168003 Localization of Fgf2 24 0.80 12.52 3.31
34 INT15648 Positive_regulation of RYR1 30 0.67 12.03 3.26
35 INT18394 Regulation of Ryr1 6 0.60 0.28 3.26
36 INT61547 Regulation of Fgf2 21 0.47 7.23 3.24
37 INT101083 Binding of Fgf2 14 0.42 4.12 3.14
38 INT26273 Negative_regulation of RYR1 18 0.43 7.64 3.11
39 INT78317 Regulation of CACNA1A 8 0.62 7.68 3.08
40 INT85572 Gene_expression of Cacna1a 11 0.66 5.72 3.02
41 INT115317 Transcription of FGF2 14 0.62 12.79 3
42 INT174864 Positive_regulation of Transcription of FGF2 8 0.44 7.58 3
43 INT88810 Positive_regulation of Gene_expression of FGF2 17 0.50 12.62 2.98
44 INT142940 Positive_regulation of Negative_regulation of Cacna1a 3 0.50 1.65 2.97
45 INT65033 Negative_regulation of Fgf2 21 0.59 12.36 2.94
46 INT86341 Positive_regulation of Cacnb3 3 0.44 0.91 2.79
47 INT355244 Negative_regulation of Negative_regulation of Cacna1a 1 0.04 0 2.67
48 INT64688 Negative_regulation of Gene_expression of Fgf2 5 0.59 5.07 2.56
49 INT140200 Regulation of Cacna2d3 4 0.45 1.48 2.53
50 INT24672 Localization of FGF2 27 0.71 14.59 2.48
51 INT161575 Localization of CACNA1A 4 0.75 5.28 2.26
52 INT19286 Negative_regulation of Cacna1c 11 0.46 5.12 2.22
53 INT48120 Positive_regulation of Cacna1h 5 0.34 1.2 2.22
54 INT99119 Gene_expression of Cacna2d3 7 0.65 1.41 2.21
55 INT97898 Regulation of FGF2 8 0.60 3.85 2.09
56 INT65207 Positive_regulation of Positive_regulation of Fgf2 10 0.70 3.5 2.08
57 INT110795 Regulation of Positive_regulation of Cacna1a 2 0.26 0.65 2.07
58 INT6508 Gene_expression of RYR1 34 0.77 11.11 2.04
59 INT87436 Regulation of Fgf2 6 0.45 3.95 2.03
60 INT112368 Positive_regulation of Cacna1c 8 0.46 2.94 1.97
61 INT99636 Negative_regulation of Localization of Fgf2 4 0.41 1.32 1.97
62 INT64687 Regulation of Gene_expression of Fgf2 7 0.62 2.29 1.89
63 INT122435 Positive_regulation of Grm7 3 0.00 1.89 1.79
64 INT354979 Positive_regulation of Localization of Cacna1a 2 0.05 0.86 1.79
65 INT355239 Negative_regulation of Positive_regulation of Cacna1a 1 0.04 0 1.79
66 INT79683 Negative_regulation of Grm7 3 0.41 2.22 1.75
67 INT71327 Localization of Cacna1a 3 0.60 2.51 1.7
68 INT92677 Positive_regulation of Gene_expression of Fgf2 11 0.69 4.25 1.68
69 INT11713 Localization of RYR1 22 0.76 10.42 1.64
70 INT123076 Gene_expression of Cacna1c 7 0.37 1.91 1.56
71 INT99117 Transcription of Cacna2d3 1 0.69 0 1.52
72 INT122547 Positive_regulation of Positive_regulation of FGF2 3 0.44 3.1 1.49
73 INT97900 Negative_regulation of Gene_expression of FGF2 9 0.57 8.37 1.48
74 INT15048 Regulation of Cacna1c 4 0.29 3.26 1.47
75 INT355242 Negative_regulation of Binding of Cacna1a 1 0.04 0.17 1.47
76 INT65452 Negative_regulation of Cacna1c 8 0.09 0.8 1.44
77 INT24671 Binding of FGF2 14 0.35 8.73 1.43
78 INT355245 Regulation of Localization of Cacna1a 1 0.04 0 1.43
79 INT90740 Negative_regulation of Cacna1a 3 0.23 1.43 1.38
80 INT86342 Negative_regulation of Cacnb3 1 0.40 0.41 1.38
81 INT79681 Localization of Grm7 5 0.78 2.57 1.34
82 INT55305 Regulation of RYR1 14 0.45 5.27 1.33
83 INT77752 Binding of Cacna1c 3 0.22 0.22 1.31
84 INT48121 Negative_regulation of Cacna1h 3 0.11 1.86 1.28
85 INT82727 Positive_regulation of Transcription of Cacna1a 1 0.01 1.07 1.25
86 INT151822 Gene_expression of Catsper1 2 0.62 2.62 1.24
87 INT130323 Regulation of Grm7 3 0.26 1.9 1.21
88 INT174866 Regulation of Gene_expression of FGF2 4 0.39 7.13 1.2
89 INT85571 Positive_regulation of Cacna1a 3 0.50 2.06 1.18
90 INT355243 Negative_regulation of Regulation of Cacna1a 1 0.04 0 1.16
91 INT66452 Positive_regulation of Cacna1c 6 0.19 2.56 1.08
92 INT140201 Positive_regulation of Binding of Cacna2d3 1 0.69 0.62 1.07
93 INT147407 Protein_catabolism of FGF2 1 0.91 0.33 1.06
94 INT336832 Gene_expression of CACNG6 1 0.78 2.88 1.01
95 INT336833 Binding of CACNG6 1 0.37 6.91 0.99
96 INT78935 Localization of Cacna1c 3 0.48 1.25 0.97
97 INT321650 Negative_regulation of Gene_expression of Cacna1a 2 0.04 0.13 0.95
98 INT184236 Positive_regulation of Localization of Fgf2 1 0.27 2.23 0.95
99 INT158378 Transcription of Grm7 1 0.00 0.65 0.94
100 INT116831 Binding of Ryr1 11 0.47 0.12 0.9
101 INT94046 Protein_catabolism of Cacna1a 1 0.70 0.83 0.9
102 INT38446 Localization of Ryr1 3 0.64 0.28 0.86
103 INT131964 Positive_regulation of CACNA1A 5 0.61 0.73 0.85
104 INT178498 Negative_regulation of Fgf2 11 0.42 4.21 0.84
105 INT77610 Gene_expression of Cacna1h 6 0.65 0.47 0.8
106 INT101886 Transcription of Fgf2 8 0.65 4.46 0.78
107 INT236517 Gene_expression of Cacna1f 8 0.65 5.18 0.77
108 INT76487 Localization of Cacna1h 3 0.48 0.98 0.77
109 INT108765 Binding of Cacna1d 1 0.06 0 0.74
110 INT123075 Positive_regulation of Gene_expression of Cacna1c 1 0.05 0.73 0.73
111 INT68589 Gene_expression of Cacna1c 14 0.58 6.36 0.69
112 INT91056 Negative_regulation of Gene_expression of Grm7 2 0.18 1.21 0.69
113 INT70104 Positive_regulation of CACNA1S 6 0.47 5.92 0.68
114 INT103336 Transcription of Cacna1a 2 0.69 1.17 0.68
115 INT141227 Phosphorylation of CACNA1A 1 0.55 0.78 0.66
116 INT345211 Positive_regulation of Grm7 1 0.02 0.64 0.66
117 INT76142 Positive_regulation of Regulation of Fgf2 2 0.47 0.34 0.64
118 INT137850 Gene_expression of PKD2 9 0.65 6.68 0.63
119 INT154199 Regulation of Localization of Grm7 1 0.60 0.92 0.62
120 INT185240 Binding of Fgf2 14 0.37 7.39 0.59
121 INT18395 Negative_regulation of Negative_regulation of Ryr1 1 0.00 0 0.59
122 INT272575 Binding of Cacng2 3 0.36 0.54 0.58
123 INT120995 Positive_regulation of Gene_expression of Grm7 1 0.00 0.57 0.57
124 INT189813 Negative_regulation of CACNA1A 4 0.57 3.07 0.55
125 INT122930 Positive_regulation of Gene_expression of CACNA1A 2 0.49 0.91 0.54
126 INT142907 Regulation of Localization of Fgf2 1 0.44 1.16 0.53
127 INT249843 Positive_regulation of Transcription of Fgf2 3 0.59 2.26 0.5
128 INT92683 Transcription of Fgf2 3 0.51 1.83 0.49
129 INT142906 Positive_regulation of Localization of Fgf2 2 0.43 1.82 0.49
130 INT243917 Binding of Cacnb3 1 0.05 0.24 0.49
131 INT15647 Regulation of Positive_regulation of RYR1 1 0.26 0.23 0.45
132 INT337348 Regulation of Gene_expression of Fgf2 2 0.45 0.54 0.44
133 INT96574 Transcription of Cacna1h 1 0.05 0.29 0.42
134 INT99118 Negative_regulation of Binding of Cacna2d3 1 0.10 0 0.41
135 INT300851 Negative_regulation of Positive_regulation of Fgf2 3 0.42 1.01 0.4
136 INT130556 Binding of CACNA1C 3 0.22 1.84 0.4
137 INT174870 Negative_regulation of Transcription of FGF2 1 0.37 1.66 0.38
138 INT303879 Positive_regulation of Gene_expression of CACNA1C 2 0.49 0.08 0.34
139 INT99962 Positive_regulation of Gene_expression of Cacna1a 1 0.01 1.1 0.34
140 INT223646 Regulation of Gene_expression of Grm7 1 0.01 4.41 0.32
141 INT155753 Regulation of Gene_expression of CACNA1A 1 0.27 0.66 0.32
142 INT80636 Positive_regulation of Localization of RYR1 2 0.47 0.78 0.29
143 INT345995 Negative_regulation of Gene_expression of Fgf2 1 0.43 0.43 0.29
144 INT101552 Binding of CACNA1F 2 0.17 1.95 0.26
145 INT264627 Positive_regulation of CACNA1C 1 0.22 0.1 0.26
146 INT243910 Phosphorylation of Cacnb3 1 0.11 0.06 0.24
147 INT101742 Regulation of Cacna1c 3 0.22 1.35 0.23
148 INT59650 Regulation of Binding of RYR1 1 0.04 0 0.23
149 INT122548 Negative_regulation of Localization of FGF2 3 0.41 1.01 0.22
150 INT279684 Positive_regulation of Catsper1 1 0.40 0.21 0.22
151 INT246083 Positive_regulation of Cacna1d 1 0.02 0.89 0.22
152 INT174869 Regulation of Negative_regulation of FGF2 1 0.39 1.59 0.22
153 INT175919 Negative_regulation of Positive_regulation of FGF2 1 0.22 0.96 0.22
154 INT223645 Positive_regulation of Gene_expression of Grm7 2 0.25 1.16 0.21
155 INT345990 Regulation of Positive_regulation of Fgf2 1 0.45 0.14 0.21
156 INT289335 Negative_regulation of Binding of Fgf2 1 0.28 0.33 0.21
157 INT49908 Regulation of Gene_expression of RYR1 3 0.45 0.32 0.19
158 INT331725 Regulation of Localization of FGF2 2 0.17 0.52 0.19
159 INT170513 Gene_expression of Cacng2 3 0.65 0.06 0.18
160 INT224030 Localization of Cacna1c 1 0.01 2.01 0.18
161 INT101741 Binding of Cacna1c 3 0.28 1.49 0.17
162 INT296813 Positive_regulation of Gene_expression of Cacna1h 1 0.06 0.19 0.17
163 INT315024 Positive_regulation of Cacna1f 1 0.41 0.5 0.17
164 INT60209 Transcription of RYR1 3 0.69 3.06 0.16
165 INT296433 Positive_regulation of Gene_expression of Cacng2 1 0.18 0 0.16
166 INT216261 Regulation of Gene_expression of Cacna1c 3 0.25 1.12 0.15
167 INT241959 Binding of Grm7 1 0.23 0 0.15
168 INT293714 Regulation of Localization of Fgf2 2 0.45 0.1 0.14
169 INT345994 Regulation of Binding of Fgf2 1 0.45 0 0.14
170 INT199810 Positive_regulation of Gene_expression of Cacna1c 2 0.43 0.81 0.13
171 INT158175 Positive_regulation of Gene_expression of RYR1 2 0.48 1.35 0.13
172 INT260482 Localization of Grm7 1 0.18 0.11 0.13
173 INT326978 Regulation of Binding of FGF2 1 0.21 0.06 0.13
174 INT170514 Gene_expression of Ryr1 4 0.49 0.56 0.12
175 INT315027 Positive_regulation of Gene_expression of Cacna1f 1 0.41 0.27 0.12
176 INT250736 Protein_catabolism of Cacna1c 1 0.14 0.06 0.12
177 INT172390 Negative_regulation of Gene_expression of Cacna1c 2 0.17 2.33 0.11
178 INT174865 Regulation of Transcription of FGF2 1 0.39 0.72 0.11
179 INT16175 Positive_regulation of CACNA1F 2 0.11 2.75 0.1
180 INT236521 Negative_regulation of Cacna1f 2 0.36 0.07 0.09
181 INT338884 Regulation of Grm7 1 0.13 0.42 0.09
182 INT338883 Positive_regulation of Regulation of Grm7 1 0.22 0.42 0.09
183 INT183123 Phosphorylation of FGF2 3 0.30 1.2 0.08
184 INT281762 Negative_regulation of Localization of Fgf2 1 0.16 1 0.08
185 INT240518 Negative_regulation of Positive_regulation of Fgf2 2 0.35 0.66 0.07
186 INT196235 Negative_regulation of Transcription of CACNA1A 1 0.36 0.1 0.07
187 INT196229 Transcription of CACNA1A 1 0.60 0.24 0.07
188 INT346730 Positive_regulation of Cacng2 1 0.49 0 0.06
189 INT286583 Localization of PKD2 1 0.35 0.17 0.06
190 INT261879 Binding of PKD2 3 0.13 2.59 0.05
191 INT170506 Positive_regulation of Positive_regulation of Cacna1c 1 0.04 0.09 0.05
192 INT108117 Regulation of CACNA1S 1 0.39 0.25 0.05
193 INT309389 Phosphorylation of Cacna1a 1 0.01 0.54 0.05
194 INT185253 Positive_regulation of Binding of Fgf2 1 0.28 0 0.05
195 INT172389 Regulation of Binding of Cacna1c 1 0.07 0.19 0.05
196 INT309386 Positive_regulation of Phosphorylation of Cacna1a 1 0.01 0.54 0.05
197 INT271024 Negative_regulation of Binding of RYR1 3 0.05 1.07 0.04
198 INT65032 Positive_regulation of Negative_regulation of Fgf2 2 0.47 0.63 0.04
199 INT279690 Negative_regulation of Catsper1 1 0.39 0 0.04
200 INT316641 Positive_regulation of Localization of Ryr1 1 0.42 0 0.04
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