GO:0005251

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Name delayed rectifier potassium channel activity
Categary Function
Go Slim No
Go Link GO:0005251
Unique Molecular Interactions 39
Total Molecular Interactions 58
Total Single Events 502
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for delayed rectifier potassium channel activity. They are ordered first by their pain relevance and then by number of times they were reported for delayed rectifier potassium channel activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT212658 KCNA1 Positive_regulation of Cort 1 0.00 2.58 3.36
2 INT212660 Nr3c1 Regulation of KCNA1 1 0.00 1.25 1.57
3 INT212662 KCNA1 Regulation of Localization of Cort 1 0.00 1.36 1.37
4 INT212661 KCNA1 Positive_regulation of Scort1 1 0.00 0.91 1.03
5 INT329120 Binding of KCNA1 and CNTNAP2 1 0.09 1.23 0.75
6 INT212659 KCNA1 Regulation of Cort 1 0.00 0.41 0.49
7 INT154592 Binding of Ntrk2 and Positive_regulation of Gene_expression of Kcna3 1 0.11 0.16 0.44
8 INT329122 Binding of KCNA1 and LGI1 1 0.08 0.29 0.43
9 INT34786 KCNA1 Positive_regulation of Localization of PRL 1 0.05 0 0.4
10 INT231206 Binding of KCNH2 and KCNQ1 2 0.22 1.04 0.24
11 INT154594 Ntf5 Positive_regulation of Gene_expression of Kcna3 1 0.05 0.07 0.23
12 INT154590 Bdnf Positive_regulation of Gene_expression of Kcna3 1 0.07 0.07 0.23
13 INT190827 KCNA1 Regulation of Localization of MUC1 1 0.05 0.08 0.22
14 INT154591 Binding of Ntrk2 and Positive_regulation of Kcna3 1 0.11 0.08 0.22
15 INT154593 Ntrk2 Regulation of Kcna3 1 0.06 0.06 0.19
16 INT210551 Binding of KCNH2 and KCNE2 1 0.08 0 0.19
17 INT149346 Negative_regulation of Kcnab1 Positive_regulation of Kcna1 1 0.01 0.08 0.18
18 INT149345 Kcnab1 Negative_regulation of Kcna1 1 0.01 0.08 0.18
19 INT149344 Kcnab1 Positive_regulation of Kcna1 1 0.01 0.08 0.18
20 INT149343 Negative_regulation of Kcnab1 Negative_regulation of Kcna1 1 0.01 0.08 0.18
21 INT329118 Binding of KCNA1 and CNTN2 1 0.02 0 0.14
22 INT326605 Binding of HTR1A and KCNH2 1 0.00 0.45 0.14
23 INT231223 Binding of KCNQ1 and Nav1 1 0.03 0.59 0.11
24 INT146754 KCNQ1 Regulation of Ros1 1 0.01 0.23 0.08
25 INT289101 Binding of KCNA1 and LEF1 1 0.00 2.58 0.03
26 INT289099 KCNA1 Positive_regulation of Gene_expression of FZD5 1 0.00 0.84 0
27 INT353872 Binding of KCNH1 and KCNH2 1 0.25 0.98 0
28 INT222138 Binding of Kcnb1 and Pirt 1 0.00 0.08 0
29 INT222137 Binding of Kcnb1 and Gcnt3 1 0.01 0 0
30 INT289102 KCNA1 Negative_regulation of Gene_expression of LEF1 1 0.00 0.44 0
31 INT289098 KCNA1 Regulation of LEF1 1 0.00 0.67 0
32 INT353871 Negative_regulation of Binding of KCNH1 and KCNH2 1 0.30 0.98 0
33 INT186402 Binding of KCNA1 and MKS1 1 0.05 0.07 0
34 INT289100 KCNA1 Regulation of Gene_expression of LEF1 1 0.00 0.68 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for delayed rectifier potassium channel activity. They are ordered first by their pain relevance and then by number of times they were reported in delayed rectifier potassium channel activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT132335 Gene_expression of KCNA1 36 0.77 18.31 13.36
2 INT93129 Negative_regulation of KCNH2 42 0.54 9.63 10.85
3 INT74075 Negative_regulation of Kcna3 20 0.59 4.68 8.64
4 INT48542 Gene_expression of Kcna3 18 0.77 6.53 7.15
5 INT86600 Gene_expression of KCNH2 37 0.78 14.88 6.14
6 INT190833 Regulation of KCNA1 8 0.53 6.61 4.66
7 INT77148 Gene_expression of Kcna1 20 0.73 4.08 4.46
8 INT34790 Localization of KCNA1 4 0.43 11.34 3.99
9 INT136266 Gene_expression of KCNQ1 23 0.64 8.34 3.11
10 INT144264 Gene_expression of KCNH1 6 0.65 17.69 2.83
11 INT143551 Binding of KCNA1 13 0.46 8.81 2.81
12 INT123795 Positive_regulation of KCNQ1 13 0.49 3.53 2.65
13 INT100743 Regulation of KCNH2 6 0.54 2.37 2.61
14 INT86602 Binding of KCNH2 14 0.36 4.65 2.58
15 INT69481 Negative_regulation of Kcna1 5 0.28 0.38 2.33
16 INT70522 Binding of Kcna1 2 0.36 0.73 2.22
17 INT95128 Positive_regulation of KCNA1 8 0.41 4.28 2.19
18 INT51584 Regulation of KCNQ1 10 0.44 3.21 1.84
19 INT100742 Regulation of Gene_expression of KCNH2 1 0.62 0.57 1.83
20 INT97985 Regulation of Kcna3 3 0.45 0.15 1.68
21 INT87571 Negative_regulation of KCNQ1 6 0.41 1.69 1.51
22 INT86486 Negative_regulation of Gene_expression of Kcna1 4 0.55 1.74 1.21
23 INT218609 Localization of Kcna1 1 0.78 0 1.15
24 INT132334 Negative_regulation of Gene_expression of KCNA1 4 0.43 1.52 1.14
25 INT154587 Transcription of Kcna3 3 0.38 1.28 1.11
26 INT70521 Regulation of Kcna1 2 0.50 0.54 1.11
27 INT87002 Negative_regulation of Gene_expression of Kcna3 2 0.35 1.78 1.09
28 INT69482 Positive_regulation of Kcna1 4 0.32 0.27 1.06
29 INT86489 Regulation of Gene_expression of Kcna1 1 0.42 0.27 1.03
30 INT137788 Negative_regulation of Positive_regulation of KCNQ1 1 0.21 1.02 0.83
31 INT132333 Negative_regulation of KCNA1 8 0.47 0.87 0.71
32 INT154586 Regulation of Gene_expression of Kcna3 1 0.28 0.22 0.59
33 INT86601 Positive_regulation of KCNH2 7 0.49 1.56 0.52
34 INT154585 Positive_regulation of Transcription of Kcna3 1 0.23 0.18 0.49
35 INT309564 Positive_regulation of KCNH1 1 0.14 0.13 0.41
36 INT74076 Positive_regulation of Kcna3 2 0.31 0.18 0.4
37 INT137786 Positive_regulation of Negative_regulation of KCNQ1 1 0.25 0.46 0.38
38 INT353887 Positive_regulation of Gene_expression of KCNH1 1 0.41 1.93 0.3
39 INT353888 Negative_regulation of Gene_expression of KCNH1 1 0.48 1.36 0.29
40 INT136267 Binding of KCNQ1 3 0.36 3.28 0.28
41 INT222131 Gene_expression of Kcnb1 1 0.67 0 0.28
42 INT154588 Negative_regulation of Transcription of Kcna3 1 0.19 0.09 0.25
43 INT149339 Positive_regulation of Positive_regulation of Kcna1 2 0.32 0.17 0.24
44 INT329151 Positive_regulation of Gene_expression of KCNA1 1 0.11 1.18 0.24
45 INT154584 Negative_regulation of Positive_regulation of Kcna3 1 0.19 0.09 0.24
46 INT154589 Positive_regulation of Gene_expression of Kcna3 1 0.23 0.07 0.23
47 INT149338 Negative_regulation of Positive_regulation of Kcna1 1 0.27 0.1 0.23
48 INT149341 Negative_regulation of Negative_regulation of Kcna1 1 0.28 0.1 0.23
49 INT210568 Positive_regulation of Localization of KCNH2 1 0.38 0 0.21
50 INT239610 Localization of KCNQ1 4 0.62 1.47 0.2
51 INT210570 Localization of KCNH2 2 0.63 0.8 0.2
52 INT34788 Negative_regulation of Localization of KCNA1 1 0.04 0 0.2
53 INT353879 Binding of KCNH1 1 0.30 1.56 0.16
54 INT147341 Negative_regulation of Binding of KCNH2 1 0.39 0.59 0.15
55 INT216248 Negative_regulation of Gene_expression of KCNQ1 1 0.38 0.33 0.14
56 INT171668 Positive_regulation of Positive_regulation of KCNH2 1 0.08 0.46 0.11
57 INT93128 Regulation of Negative_regulation of KCNH2 1 0.31 0 0.07
58 INT218610 Transcription of Kcna1 1 0.51 1.05 0.07
59 INT218606 Regulation of Transcription of Kcna1 1 0.26 1.05 0.07
60 INT222132 Positive_regulation of Gene_expression of Kcnb1 1 0.38 0 0.05
61 INT222136 Positive_regulation of Kcnb1 1 0.38 0 0.05
62 INT222134 Negative_regulation of Gene_expression of Kcnb1 1 0.37 0 0.04
63 INT210569 Negative_regulation of Gene_expression of KCNH2 2 0.41 0 0.03
64 INT353882 Regulation of KCNH1 1 0.37 1.04 0.03
65 INT204916 Regulation of Gene_expression of KCNA1 1 0.45 0.06 0
66 INT353886 Localization of KCNH1 1 0.61 0.8 0
67 INT353884 Negative_regulation of Localization of KCNH1 1 0.35 0.8 0
68 INT353880 Negative_regulation of Localization of KCNH2 1 0.36 0.8 0
69 INT142323 Negative_regulation of Negative_regulation of KCNH2 1 0.51 0 0
70 INT62353 Negative_regulation of Kcnb1 1 0.41 0 0
71 INT353881 Negative_regulation of KCNH1 1 0.35 0.89 0
72 INT353885 Positive_regulation of Gene_expression of KCNH2 1 0.42 1.28 0
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