GO:0005260

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Name channel-conductance-controlling ATPase activity
Categary Function
Go Slim No
Go Link GO:0005260
Unique Molecular Interactions 25
Total Molecular Interactions 31
Total Single Events 605
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for channel-conductance-controlling ATPase activity. They are ordered first by their pain relevance and then by number of times they were reported for channel-conductance-controlling ATPase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT162419 Binding of Abpa and Cftr 1 0.04 1.66 1.19
2 INT170832 Cftr Regulation of Scnn1a 2 0.16 1.2 0.67
3 INT170833 Cftr Negative_regulation of Slc10a2 1 0.47 0.31 0.56
4 INT69291 Cftr Positive_regulation of Localization of Slc4a8 1 0.04 0.38 0.51
5 INT117482 CFTR Negative_regulation of THRB 1 0.01 0.15 0.51
6 INT341623 Binding of CFTR and CTRC 1 0.35 1.22 0.46
7 INT341624 Binding of CFTR and PRSS1 1 0.39 1.01 0.45
8 INT352547 Binding of CFTR and DMD 1 0.01 1.42 0.35
9 INT310696 Tlr4 Positive_regulation of Positive_regulation of Cftr 1 0.16 0.74 0.28
10 INT196695 Prkaca Positive_regulation of CFTR 1 0.46 0.13 0.27
11 INT274697 Binding of CFTR and Cftr 1 0.08 0.69 0.27
12 INT170834 Cftr Regulation of Slc10a2 1 0.58 0.37 0.22
13 INT196635 CFTR Positive_regulation of Gene_expression of CCL5 1 0.07 0.44 0.21
14 INT196610 IFNG Negative_regulation of CFTR 1 0.17 0.21 0.19
15 INT267660 CFTR Regulation of Gene_expression of P2RX2 1 0.25 0.51 0.18
16 INT196606 IFNG Positive_regulation of CFTR 1 0.16 0.45 0.16
17 INT127206 Negative_regulation of Cftr Negative_regulation of Positive_regulation of Mcf2l 1 0.16 0.62 0.16
18 INT196608 TNF Negative_regulation of CFTR 1 0.16 0.11 0.14
19 INT216545 Gene_expression of Cftr Negative_regulation of Kcnma1 1 0.00 0.59 0.06
20 INT196639 Negative_regulation of NA Negative_regulation of Transcription of CFTR 1 0.02 0.63 0.03
21 INT213585 Binding of CFTR and FLNA 1 0.14 0.11 0.03
22 INT310694 Tlr4 Positive_regulation of Cftr 1 0.16 0.34 0.03
23 INT308747 Binding of Cftr and Prkag1 1 0.02 0 0
24 INT247030 Prkaca Regulation of Positive_regulation of Cftr 1 0.05 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for channel-conductance-controlling ATPase activity. They are ordered first by their pain relevance and then by number of times they were reported in channel-conductance-controlling ATPase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT103842 Gene_expression of Cftr 53 0.78 59.59 21.82
2 INT84307 Binding of Cftr 31 0.47 26.19 12.8
3 INT119892 Gene_expression of Cftr 54 0.77 23.76 9.73
4 INT77282 Positive_regulation of Cftr 23 0.69 21.8 9.65
5 INT101891 Negative_regulation of Cftr 25 0.58 24.09 9.55
6 INT138802 Gene_expression of CFTR 36 0.70 18.8 7.02
7 INT69289 Negative_regulation of Cftr 44 0.57 13.28 6.97
8 INT86119 Regulation of Cftr 13 0.45 14.08 5.75
9 INT151102 Positive_regulation of CFTR 22 0.61 15.27 5.12
10 INT89114 Binding of Cftr 13 0.37 11.29 4.99
11 INT170757 Positive_regulation of Gene_expression of Cftr 3 0.51 11.41 4.75
12 INT169756 Binding of CFTR 9 0.35 9.65 4.55
13 INT48993 Positive_regulation of Cftr 17 0.57 6.02 4.12
14 INT89113 Regulation of Cftr 11 0.62 6.83 4.01
15 INT151099 Negative_regulation of CFTR 12 0.59 10.28 3.79
16 INT69290 Localization of Cftr 11 0.75 3.69 2.52
17 INT86315 Transcription of Cftr 7 0.53 4.24 2.3
18 INT202522 Negative_regulation of Gene_expression of Cftr 11 0.57 5.9 2.24
19 INT166710 Positive_regulation of Gene_expression of CFTR 9 0.46 3.72 2.03
20 INT119891 Regulation of Gene_expression of Cftr 4 0.59 2.67 1.98
21 INT151101 Regulation of CFTR 4 0.62 3.69 1.89
22 INT84308 Localization of Cftr 12 0.75 6.16 1.65
23 INT108281 Negative_regulation of Binding of Cftr 4 0.43 3.1 1.38
24 INT139625 Regulation of Gene_expression of Cftr 5 0.50 3.59 1.32
25 INT196675 Localization of CFTR 4 0.64 1.95 1.19
26 INT86314 Regulation of Transcription of Cftr 2 0.33 1.81 0.83
27 INT61290 Regulation of Phosphorylation of CFTR 1 0.44 0.25 0.81
28 INT274693 Positive_regulation of Gene_expression of Cftr 6 0.49 2.93 0.8
29 INT61291 Phosphorylation of CFTR 1 0.80 0.25 0.8
30 INT196682 Negative_regulation of Gene_expression of CFTR 6 0.34 1.96 0.73
31 INT151100 Negative_regulation of Positive_regulation of CFTR 1 0.43 1.11 0.73
32 INT127204 Negative_regulation of Positive_regulation of Cftr 1 0.43 1.9 0.69
33 INT215828 Regulation of Binding of Cftr 2 0.33 1.56 0.66
34 INT103841 Negative_regulation of Gene_expression of Cftr 3 0.43 1.93 0.63
35 INT151098 Positive_regulation of Positive_regulation of CFTR 2 0.50 0.9 0.63
36 INT170759 Positive_regulation of Binding of Cftr 2 0.50 1.82 0.6
37 INT348872 Positive_regulation of Regulation of Cftr 1 0.34 1.3 0.55
38 INT310689 Positive_regulation of Negative_regulation of Cftr 1 0.47 1.41 0.4
39 INT226184 Protein_catabolism of Cftr 3 0.87 1.52 0.38
40 INT170758 Positive_regulation of Localization of Cftr 2 0.50 2.4 0.35
41 INT170756 Negative_regulation of Localization of Cftr 1 0.42 1.74 0.31
42 INT267666 Regulation of Localization of CFTR 1 0.22 0.39 0.3
43 INT120959 Protein_catabolism of CFTR 1 0.03 0.14 0.28
44 INT132710 Negative_regulation of Regulation of Cftr 1 0.06 0.1 0.27
45 INT196688 Positive_regulation of Binding of CFTR 1 0.26 0.33 0.24
46 INT308734 Transcription of Cftr 1 0.68 0.75 0.2
47 INT196681 Negative_regulation of Localization of CFTR 1 0.34 0.18 0.15
48 INT310692 Positive_regulation of Protein_catabolism of Cftr 1 0.44 0.46 0.12
49 INT196672 Positive_regulation of Localization of CFTR 1 0.41 0 0.1
50 INT347555 Positive_regulation of Localization of Cftr 1 0.14 0.63 0.09
51 INT308732 Regulation of Transcription of Cftr 1 0.44 0.18 0.09
52 INT308735 Negative_regulation of Positive_regulation of Cftr 1 0.42 0.15 0.08
53 INT196673 Regulation of Gene_expression of CFTR 1 0.36 0.62 0.08
54 INT274694 Negative_regulation of Binding of Cftr 1 0.35 0.19 0.05
55 INT196683 Negative_regulation of Transcription of CFTR 1 0.22 0.61 0.03
56 INT196685 Transcription of CFTR 1 0.37 0.6 0.03
57 INT308731 Phosphorylation of Cftr 1 0.62 0 0
58 INT216564 Regulation of Negative_regulation of Cftr 1 0.24 0.12 0
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