GO:0005261

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Name cation channel activity
Categary Function
Go Slim No
Go Link GO:0005261
Unique Molecular Interactions 1030
Total Molecular Interactions 1498
Total Single Events 15812
Pain Genes Associated 48

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cation channel activity. They are ordered first by their pain relevance and then by number of times they were reported for cation channel activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36
2 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25
3 INT251170 Clu Positive_regulation of Trpv1 1 0.28 2.61 6.49
4 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 0.74 4.31 6.1
5 INT351352 Binding of Trpv1 and Lpar1 1 0.21 5.86 4.62
6 INT180774 Gdnf Positive_regulation of Trpv1 1 0.33 2.43 4.37
7 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79
8 INT136525 Binding of Prokr1 and Trpv1 1 0.39 2.9 3.76
9 INT141254 Ngf Regulation of Transcription of Trpv1 1 0.53 1.37 3.74
10 INT158770 Binding of Trpv1 and Trpa1 5 0.34 2.07 3.5
11 INT195931 Binding of OPRM1 and Trpv1 1 0.07 0.87 3.43
12 INT354207 Igfbp7 Positive_regulation of Accn3 1 0.52 6.55 3.24
13 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
14 INT251146 Binding of Grin1 and Dlg2 1 0.36 1.95 3.16
15 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11
16 INT101408 Binding of Grin1 and Olr1469 1 0.03 0.86 3.1
17 INT101407 Binding of Grin1 and Spr 1 0.14 0.86 3.09
18 INT122776 Gdnf Positive_regulation of Gene_expression of Trpv1 2 0.67 2.13 3.06
19 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
20 INT156381 Binding of Grin1 and Dlg4 1 0.39 0.86 2.9
21 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79
22 INT182564 Binding of Ptger2 and Trpv1 1 0.18 1.77 2.67
23 INT351444 Grin1 Positive_regulation of Gria2 1 0.22 1.5 2.64
24 INT210696 Trpv1 Regulation of Slc12a2 1 0.25 1.97 2.58
25 INT317528 Ppp1r9b Regulation of Grin1 1 0.18 0.2 2.48
26 INT251147 Binding of Grin2b and Dlg2 1 0.33 2.75 2.43
27 INT122775 Gdnf Regulation of Gene_expression of Trpv1 4 0.59 2.72 2.42
28 INT107578 Kitl Negative_regulation of Grin2b 1 0.12 2.05 2.36
29 INT107165 Binding of Gabrg1 and Trpv1 2 0.01 0.16 2.34
30 INT228454 Ngf Positive_regulation of Phosphorylation of Trpv1 1 0.39 2.97 2.26
31 INT251164 Binding of Clu and Trpv1 1 0.19 0.44 2.23
32 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21
33 INT140659 Phax Positive_regulation of Trpv1 3 0.49 0.68 2.18
34 INT113451 Ngf Regulation of Gene_expression of ASIC3 1 0.07 1.35 2.18
35 INT251145 Binding of Grin2a and Dlg2 1 0.31 2.3 2.11
36 INT113452 Ngf Positive_regulation of Gene_expression of ASIC3 1 0.19 1.34 2.08
37 INT167530 Phax Regulation of Gene_expression of Trpv1 1 0.16 0.86 2.05
38 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
39 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
40 INT262558 Phax Positive_regulation of Trpv1 1 0.01 1.26 1.92
41 INT93293 Ngf Regulation of Trpv1 2 0.28 0.71 1.9
42 INT161079 Mcs18 Negative_regulation of Trpv1 1 0.40 0.82 1.9
43 INT166945 Ngf Positive_regulation of Trpv1 1 0.01 0.47 1.88
44 INT338691 Binding of Trpv1 and Aff3 1 0.24 1.21 1.88
45 INT297488 Itpr3 Regulation of Positive_regulation of Ltp 1 0.02 0.47 1.87
46 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
47 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
48 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 0.30 1.36 1.8
49 INT23392 Gal Regulation of Trpv1 1 0.05 0.33 1.77
50 INT276863 Gpr65 Regulation of Trpv1 1 0.25 1.78 1.75
51 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75
52 INT182565 Ptger2 Regulation of Trpv1 1 0.25 1.34 1.73
53 INT354210 Binding of Igfbp7 and Accn3 1 0.27 3.91 1.64
54 INT276670 Binding of Trpv1 and Nkx1-1 1 0.07 0.68 1.6
55 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
56 INT131575 Grin1 Negative_regulation of Positive_regulation of Ephb1 1 0.28 0.31 1.58
57 INT168608 Binding of Grin2b and Mmp9 1 0.22 0.41 1.57
58 INT208980 Binding of Ca2 and Trpv1 4 0.32 0.67 1.55
59 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55
60 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
61 INT42000 Trpv1 Positive_regulation of Cck 1 0.04 0 1.49
62 INT41999 Trpv1 Positive_regulation of Vip 1 0.04 0 1.49
63 INT140329 Grin1 Negative_regulation of Ltp 1 0.04 0.64 1.46
64 INT121226 Ngf Regulation of Gene_expression of Trpv1 2 0.62 0.7 1.44
65 INT180789 Ngf Regulation of Localization of Trpv1 1 0.28 1.22 1.44
66 INT180768 Bdnf Regulation of Localization of Trpv1 1 0.13 1.21 1.43
67 INT180790 Gdnf Regulation of Localization of Trpv1 1 0.15 1.21 1.43
68 INT246519 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.25 0.08 1.42
69 INT144123 Binding of P2rx6 and Trpv1 1 0.11 0 1.4
70 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
71 INT138099 Binding of Grin2a and Insrr 1 0.01 0.36 1.39
72 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38
73 INT167529 Ppt1 Negative_regulation of Gene_expression of Trpv1 1 0.26 0.49 1.38
74 INT182558 Binding of Ptgir and Trpv1 1 0.16 1.12 1.37
75 INT276673 Nkx1-1 Regulation of Trpv1 1 0.05 0.16 1.37
76 INT261483 Binding of Ephb1 and Trpv1 1 0.39 1.37 1.37
77 INT355248 Ltp Positive_regulation of Localization of Trpv1 1 0.51 0 1.35
78 INT121457 KNG1 Positive_regulation of Trpv1 1 0.16 0.91 1.33
79 INT317519 Grin1 Positive_regulation of Negative_regulation of Oprm1 1 0.14 0 1.31
80 INT242605 Gdnf Positive_regulation of Trpv1 1 0.26 0.17 1.3
81 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29
82 INT208990 Binding of CALM1 and Trpv1 1 0.10 0.07 1.29
83 INT154518 Binding of Ephb6 and Grin2b 1 0.21 0.24 1.28
84 INT125950 Syt17 Regulation of Trpv1 1 0.11 0.43 1.28
85 INT64077 Trpv1 Positive_regulation of Kcnma1 1 0.00 0.37 1.27
86 INT251142 Binding of Dlg4 and Grin2a 3 0.30 0.5 1.24
87 INT314198 Mapk14 Positive_regulation of Gene_expression of Trpv1 1 0.48 1.09 1.24
88 INT195926 Prkaca Positive_regulation of Trpv1 1 0.10 0.44 1.24
89 INT147033 Positive_regulation of Binding of Sds and Accn3 1 0.13 0.73 1.23
90 INT147032 Binding of Sds and Accn3 1 0.09 0.73 1.22
91 INT142154 Trpv1 Positive_regulation of Gene_expression of Il2 1 0.22 0 1.21
92 INT112105 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2b 2 0.40 0.89 1.2
93 INT166301 Adrbk1 Positive_regulation of Localization of Trpv1 1 0.45 1.17 1.2
94 INT93294 Ngf Regulation of Transcription of Trpv1 1 0.01 0.36 1.19
95 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19
96 INT107579 Kitl Negative_regulation of Grin2a 1 0.10 1.02 1.18
97 INT93290 Ngf Regulation of Transcription of Trpv1 1 0.02 0.34 1.16
98 INT93289 Ngf Regulation of Trpv1 1 0.05 0.34 1.16
99 INT121725 Binding of Trpv1 and Pik3cb 1 0.35 0.62 1.15
100 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
101 INT160653 Binding of P2rx1 and Ptgfr 1 0.28 0.66 1.14
102 INT317553 Binding of Car2 and Grin1 1 0.07 0 1.14
103 INT110669 Binding of Alox5 and Trpv1 1 0.07 0.2 1.13
104 INT121362 Trpv1 Regulation of Localization of Ins1 1 0.51 0.17 1.12
105 INT332776 FSCN1 Positive_regulation of Grin1 1 0.02 0.21 1.12
106 INT182550 Ptger1 Negative_regulation of Trpv1 1 0.35 0.73 1.12
107 INT132683 Bdnf Positive_regulation of Phosphorylation of Grin2a 1 0.00 0.93 1.11
108 INT122268 Binding of Grin2b and Grm5 1 0.40 0.52 1.1
109 INT269191 Binding of Grin1 and Grin3a 2 0.32 1.05 1.09
110 INT269189 Binding of Grin2a and Grin3a 2 0.25 1.05 1.09
111 INT121730 Pik3cb Regulation of Trpv1 1 0.58 0.54 1.09
112 INT305734 Binding of Sort1 and Trpv1 1 0.01 0.5 1.08
113 INT317561 Binding of Grin1 and Oprm1 1 0.14 0.09 1.08
114 INT256294 Binding of Grin2b and Ephb1 1 0.28 1.11 1.08
115 INT181493 TRPV4 Regulation of Gene_expression of NGF 1 0.24 0.7 1.07
116 INT269193 Prkcg Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
117 INT269192 Ephb1 Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
118 INT269198 Prkaca Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
119 INT291966 Pag1 Positive_regulation of Gene_expression of Grin2b 1 0.19 1.91 1.06
120 INT317531 Regulation of Binding of Grin1 and Mors1 1 0.08 0.06 1.05
121 INT317534 Regulation of Binding of Camk2a and Grin1 1 0.20 0.06 1.05
122 INT256293 Binding of Grin2b and Insrr 1 0.01 1.06 1.05
123 INT269199 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.03 0.56 1.05
124 INT154846 Negative_regulation of Mapk14 Negative_regulation of Positive_regulation of Trpv1 1 0.23 0.07 1.05
125 INT317535 Binding of Grin1 and Mors1 1 0.07 0.06 1.04
126 INT291964 Phex Regulation of Gene_expression of Grin2b 1 0.08 1.39 1.04
127 INT130167 Trpv1 Regulation of Localization of Calca 2 0.38 0.69 1.03
128 INT346835 Gene_expression of Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.27 1.07 1.03
129 INT114553 Binding of Trpv1 and Col4a4 1 0.01 0.44 1.03
130 INT114554 Binding of St3gal3 and Trpv1 1 0.01 0.44 1.03
131 INT263232 Prkcg Positive_regulation of Trpv4 1 0.12 1.1 1.02
132 INT269194 Ceacam3 Positive_regulation of Phosphorylation of Grin1 1 0.09 0.55 1.02
133 INT148327 Binding of Pkd1 and Trpv1 1 0.52 2.23 1.01
134 INT131889 gr Regulation of Gene_expression of Grin1 1 0.02 0 1.01
135 INT186161 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.11 1.05 1.01
136 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01
137 INT317532 Grin1 Regulation of Negative_regulation of Oprm1 1 0.18 0.07 1
138 INT263227 Positive_regulation of Prkcg Regulation of Trpv4 1 0.07 0.95 1
139 INT283932 Positive_regulation of Mapk14 Regulation of Gene_expression of Trpv1 1 0.14 1.28 0.99
140 INT156510 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.03 0.98 0.98
141 INT344389 Ephb2 Positive_regulation of Phosphorylation of Grin2b 1 0.16 1.46 0.98
142 INT156508 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.22 0.98 0.98
143 INT353372 Dio1 Positive_regulation of Grin1 1 0.16 0 0.98
144 INT307100 Trpv1 Regulation of Binding of Trpa1 1 0.31 1.81 0.97
145 INT156380 Regulation of Binding of Grin1 and Dlg4 1 0.29 0.32 0.97
146 INT307103 Trpa1 Regulation of Binding of Trpv1 1 0.31 1.81 0.97
147 INT240457 Binding of Ppyr1 and Grina 1 0.06 0.42 0.96
148 INT122144 Binding of Trpv1 and Prkd1 1 0.02 0.39 0.96
149 INT152084 Edn1 Negative_regulation of Positive_regulation of Trpv1 1 0.62 0.48 0.96
150 INT354224 Bdnf Positive_regulation of Transcription of Accn3 1 0.09 1.04 0.95
151 INT156608 Trpv1 Regulation of Nav1 1 0.51 0.52 0.95
152 INT136033 Edn1 Positive_regulation of Trpv1 1 0.50 0.34 0.95
153 INT144902 Binding of Trpv1 and Pars2 1 0.17 0 0.95
154 INT199396 Prok2 Regulation of Trpv1 1 0.43 1.23 0.94
155 INT344381 Olfr360 Negative_regulation of Gene_expression of Grin2b 1 0.01 1.17 0.93
156 INT344390 Olfr360 Negative_regulation of Phosphorylation of Grin2b 1 0.01 1.17 0.93
157 INT344388 Efnb1 Positive_regulation of Phosphorylation of Grin2b 1 0.40 1.45 0.92
158 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
159 INT251153 Dlg2 Positive_regulation of Gene_expression of Grin2a 1 0.40 0.6 0.92
160 INT80718 Trpv3 Negative_regulation of Chn1 1 0.01 0.7 0.92
161 INT195927 Binding of Prkaca and Trpv1 1 0.07 0.28 0.92
162 INT251152 Dlg2 Positive_regulation of Localization of Grin2b 1 0.43 0.6 0.92
163 INT215584 P2rx1 Regulation of Localization of Gabrg1 1 0.01 0 0.92
164 INT291962 Pag1 Negative_regulation of Gene_expression of Grin2b 1 0.17 1.56 0.92
165 INT149386 Binding of Lyn and TRPV4 1 0.40 1.14 0.91
166 INT109842 Prkce Positive_regulation of Localization of Trpv1 1 0.13 1.31 0.91
167 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
168 INT108647 Binding of Grin2a and Camk1d 1 0.33 0.78 0.9
169 INT180772 Bdnf Regulation of Trpv1 1 0.11 0.29 0.9
170 INT180777 Bdnf Regulation of Gene_expression of Trpv1 1 0.18 0.29 0.9
171 INT108438 Grin2b Regulation of Pdyn 1 0.16 0.25 0.9
172 INT326455 Runx1 Positive_regulation of Gene_expression of Trpv1 1 0.45 0 0.88
173 INT251159 Binding of Clu and Positive_regulation of Trpv1 1 0.16 0 0.87
174 INT52195 Sigmar1 Positive_regulation of Positive_regulation of Grin1 1 0.15 0 0.87
175 INT152868 Tnf Regulation of Gene_expression of Trpv1 1 0.27 0.25 0.86
176 INT222243 Negative_regulation of Binding of Trpv1 and Ccr5 1 0.21 0.57 0.86
177 INT222244 Binding of Trpv1 and Ccr5 1 0.19 0.57 0.86
178 INT193278 Brs3 Positive_regulation of Gene_expression of Trpv1 1 0.04 0.09 0.86
179 INT114546 Ins1 Positive_regulation of Positive_regulation of Trpv1 1 0.39 0.19 0.86
180 INT182555 Ptgir Regulation of Trpv1 1 0.12 0.61 0.85
181 INT338695 CAP1 Regulation of Trpv1 1 0.01 0.14 0.85
182 INT120820 Binding of ASIC3 and Dlg4 3 0.02 0.11 0.84
183 INT140660 Phax Negative_regulation of Trpv1 2 0.08 0.58 0.84
184 INT140004 Srxn1 Negative_regulation of Accn2 1 0.01 0.47 0.83
185 INT152083 Binding of Edn1 and Trpv1 1 0.38 0.67 0.83
186 INT212290 Binding of Grin2a and Grin2b 2 0.20 1.36 0.82
187 INT98479 Lif Regulation of Gene_expression of Grin1 1 0.04 0.35 0.82
188 INT124292 Binding of Trpv1 and F2rl1 1 0.46 1.1 0.81
189 INT157913 Trpv1 Regulation of Gene_expression of Edn1 1 0.29 0.55 0.81
190 INT251172 Trpv1 Regulation of Gene_expression of Ca2 1 0.13 0.7 0.81
191 INT100559 Binding of Grin1 and LOC502940 1 0.13 0.61 0.8
192 INT219911 Edn1 Regulation of Gene_expression of Trpv1 1 0.23 0.57 0.8
193 INT192134 Ngf Positive_regulation of Trpv1 1 0.18 1.22 0.79
194 INT125353 Binding of Sst and Trpv1 1 0.36 0.5 0.79
195 INT54800 Grin1 Regulation of Gene_expression of Gh 1 0.01 0 0.79
196 INT281651 Phax Positive_regulation of Gene_expression of Trpv1 1 0.09 0.89 0.79
197 INT157914 Trpv1 Regulation of Prkca 1 0.07 0.55 0.78
198 INT145430 oh Positive_regulation of Trpv1 1 0.05 0.15 0.78
199 INT351364 LPA Positive_regulation of Trpv1 1 0.02 1.15 0.78
200 INT262562 F2rl1 Regulation of Trpv1 1 0.12 0.58 0.77

Single Events

The table below shows the top 100 pain related interactions that have been reported for cation channel activity. They are ordered first by their pain relevance and then by number of times they were reported in cation channel activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59
2 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42
3 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42
4 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59
5 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61
6 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24
7 INT60126 Regulation of Trpv1 186 0.62 85.53 133.4
8 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75
9 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38
10 INT89054 Positive_regulation of Gene_expression of Trpv1 156 0.70 90.78 102.03
11 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48
12 INT38731 Localization of Trpv1 138 0.81 52.73 90.49
13 INT4830 Binding of Trpv1 158 0.48 45.11 84.2
14 INT92518 Gene_expression of Grin2b 131 0.78 65.52 80.91
15 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7
16 INT98621 Regulation of Trpv1 121 0.62 79.24 75.23
17 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42
18 INT87686 Positive_regulation of Gene_expression of Trpv1 101 0.70 72.41 69.15
19 INT96622 Localization of Trpv1 110 0.81 59.82 63.25
20 INT90911 Positive_regulation of Phosphorylation of Grin1 62 0.70 27.45 59.26
21 INT7340 Regulation of Grin1 87 0.62 30.37 57.93
22 INT4957 Negative_regulation of Grin1 87 0.59 24.51 53.21
23 INT51627 Gene_expression of Grin2a 82 0.76 25.09 47.6
24 INT57021 Positive_regulation of Gene_expression of Grin1 62 0.70 24.77 47.31
25 INT98498 Binding of Trpv1 75 0.48 33.67 44.4
26 INT94029 Positive_regulation of Grin2b 58 0.70 24.2 42.52
27 INT81251 Gene_expression of Trpv2 78 0.78 28.27 41.76
28 INT92517 Gene_expression of Grin1 105 0.78 29.53 39.43
29 INT92515 Gene_expression of Grin2a 84 0.76 26.68 38.37
30 INT58062 Negative_regulation of Gene_expression of Trpv1 66 0.59 22.34 38.02
31 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14
32 INT11246 Binding of Grin1 65 0.48 14.53 36.93
33 INT80075 Regulation of Gene_expression of Trpv1 55 0.62 32.42 36.88
34 INT64436 Gene_expression of P2rx1 93 0.78 32.69 36.12
35 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08
36 INT98521 Gene_expression of Accn2 52 0.74 23.45 35.09
37 INT130479 Phosphorylation of Grin2b 28 0.77 34.82 34.97
38 INT76531 Transcription of Trpv1 62 0.72 23.69 34.77
39 INT52194 Positive_regulation of Grin1 83 0.69 25.09 34.76
40 INT96624 Positive_regulation of Positive_regulation of Trpv1 62 0.70 20.5 34.28
41 INT109820 Gene_expression of Trpv4 121 0.78 39.69 33.11
42 INT57024 Regulation of Gene_expression of Grin1 32 0.62 9.77 32.6
43 INT93451 Positive_regulation of Gene_expression of Grin2b 43 0.70 29.09 31.89
44 INT70776 Positive_regulation of P2rx1 62 0.62 32.55 30.75
45 INT106540 Negative_regulation of Phosphorylation of Grin1 15 0.58 9.32 29.13
46 INT98522 Gene_expression of Accn3 68 0.78 26.95 28.6
47 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54
48 INT80470 Negative_regulation of Gene_expression of Grin1 33 0.59 10.22 27.15
49 INT32794 Gene_expression of Grin2d 81 0.68 20.87 26.99
50 INT112036 Phosphorylation of Trpv1 51 0.82 18.59 25.6
51 INT103320 Positive_regulation of Positive_regulation of Trpv1 44 0.70 27.73 25.28
52 INT92105 Transcription of Trpv1 47 0.71 27.47 25.01
53 INT107577 Negative_regulation of Grin2b 32 0.59 12.35 24.88
54 INT100124 Gene_expression of Accn3 38 0.78 30.02 23.63
55 INT125190 Regulation of Gene_expression of Trpv1 38 0.62 32.57 23.2
56 INT89056 Phosphorylation of Trpv1 46 0.82 13.52 22.16
57 INT102281 Positive_regulation of Gene_expression of Grin2b 27 0.70 10.38 20.84
58 INT112174 Gene_expression of Trpv4 47 0.78 26.26 20.09
59 INT96511 Negative_regulation of Positive_regulation of Trpv1 35 0.59 10.95 19.79
60 INT90612 Positive_regulation of Grin2a 33 0.65 15.11 18.84
61 INT50420 Transcription of Grin1 30 0.71 13.21 18.28
62 INT90937 Negative_regulation of Gene_expression of Trpv1 34 0.59 22.74 18.12
63 INT63928 Negative_regulation of Grin1 51 0.56 11.81 17.57
64 INT119233 Positive_regulation of Trpv4 65 0.70 20.21 17.3
65 INT16624 Localization of Grin1 38 0.79 8.46 17.15
66 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92
67 INT92514 Regulation of Grin2b 22 0.50 11.07 16.92
68 INT88356 Negative_regulation of Positive_regulation of Grin1 16 0.58 4.72 16.58
69 INT81087 Gene_expression of ASIC3 30 0.75 13.62 16.54
70 INT14647 Positive_regulation of Grin2a 26 0.67 4.69 14.8
71 INT91913 Regulation of GRIN3B 16 0.61 11.48 14.44
72 INT115071 Positive_regulation of Accn3 14 0.70 16.56 14.24
73 INT92513 Regulation of Grin1 26 0.59 9.12 13.94
74 INT65697 Positive_regulation of GRIN3B 23 0.69 12.52 13.78
75 INT7342 Positive_regulation of Positive_regulation of Grin1 18 0.50 9.22 13.76
76 INT90942 Regulation of P2rx1 31 0.61 16.61 13.69
77 INT97848 Positive_regulation of Localization of Trpv1 18 0.50 7.66 13.36
78 INT101494 Regulation of Positive_regulation of Trpv1 18 0.62 6.57 12.9
79 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85
80 INT119089 Regulation of Phosphorylation of Grin1 17 0.61 3.1 12.82
81 INT103997 Phosphorylation of Grin2a 17 0.64 10.75 12.67
82 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55
83 INT81249 Positive_regulation of Trpv2 21 0.70 8.13 12.36
84 INT100799 Negative_regulation of Grin2a 27 0.57 7.33 12.2
85 INT112103 Binding of Grin1 28 0.48 4.21 12.08
86 INT145515 Positive_regulation of Localization of Trpv1 23 0.50 10.12 12.08
87 INT96406 Regulation of Trpv2 14 0.62 7.45 12.04
88 INT51625 Regulation of Gene_expression of Grin2a 12 0.60 3.28 11.6
89 INT98524 Positive_regulation of Accn2 15 0.49 9.48 11.57
90 INT48883 Negative_regulation of GRIN3B 19 0.54 14.53 11.5
91 INT68290 Gene_expression of Accn1 32 0.73 7.36 11.23
92 INT130475 Positive_regulation of Phosphorylation of Grin2b 8 0.47 11.52 10.96
93 INT79556 Gene_expression of GRIN3B 16 0.77 7.71 10.75
94 INT112037 Negative_regulation of Positive_regulation of Trpv1 19 0.59 8.9 10.55
95 INT51626 Transcription of Grin2a 16 0.68 1.65 10.5
96 INT93036 Negative_regulation of Grin2a 23 0.50 7.1 10.32
97 INT64193 Regulation of Grin2a 19 0.54 2.98 10.31
98 INT109578 Positive_regulation of Accn3 16 0.70 9.09 10.05
99 INT80717 Gene_expression of Trpv3 20 0.72 10.05 9.96
100 INT80006 Regulation of Gene_expression of Grin2b 8 0.57 3.75 9.62
101 INT89053 Positive_regulation of Phosphorylation of Trpv1 16 0.70 8.89 9.39
102 INT107898 Gene_expression of Trpv2 27 0.76 10.55 9.28
103 INT78769 Regulation of Grin2a 16 0.58 5.22 9.28
104 INT93191 Gene_expression of Accn2 22 0.76 10.04 8.91
105 INT121987 Phosphorylation of Grin1 11 0.80 4.73 8.88
106 INT120651 Positive_regulation of Gene_expression of Accn2 13 0.66 9.02 8.58
107 INT70775 Positive_regulation of Positive_regulation of P2rx1 15 0.49 8.65 8.49
108 INT31761 Positive_regulation of Itpr3 32 0.58 5.95 8.22
109 INT124702 Positive_regulation of Trpv4 21 0.69 7.14 8.2
110 INT112104 Binding of Grin2b 21 0.44 6.78 8.16
111 INT117642 Regulation of Gene_expression of Grin1 18 0.53 7.09 8.08
112 INT95172 Localization of P2rx1 14 0.78 6.77 7.81
113 INT135113 Localization of Grin1 18 0.73 3.73 7.69
114 INT48882 Binding of GRIN3B 9 0.46 5.12 7.66
115 INT110705 Positive_regulation of Positive_regulation of Grin1 11 0.69 4.7 7.33
116 INT90943 Negative_regulation of P2rx1 13 0.42 8.21 7.22
117 INT114014 Positive_regulation of Gene_expression of P2rx1 13 0.69 7.77 7.15
118 INT91351 Gene_expression of P2rx1 28 0.75 5.89 6.78
119 INT126989 Transcription of Accn2 8 0.63 5.22 6.77
120 INT154773 Regulation of Accn3 7 0.62 7.09 6.63
121 INT136496 Regulation of Accn3 5 0.45 3.72 6.53
122 INT50419 Gene_expression of Grina 13 0.25 6.11 6.42
123 INT100926 Positive_regulation of Gene_expression of Grin2a 11 0.63 3.24 6.41
124 INT93193 Positive_regulation of Accn2 16 0.69 7.2 6.37
125 INT93195 Negative_regulation of Accn2 14 0.59 7.23 6.31
126 INT124881 Binding of Trpv4 35 0.47 7.71 6.24
127 INT100658 Negative_regulation of Positive_regulation of Grin2b 7 0.41 1.39 6.17
128 INT71758 Gene_expression of P2RX1 40 0.75 9.01 6.14
129 INT149385 Positive_regulation of TRPV4 11 0.69 7.22 6.02
130 INT118440 Gene_expression of TRPV4 20 0.71 7.33 6.01
131 INT103319 Regulation of Positive_regulation of Trpv1 11 0.45 8.37 5.99
132 INT74593 Transcription of Grin2b 10 0.66 1.21 5.98
133 INT130472 Negative_regulation of Phosphorylation of Grin2b 4 0.40 4.4 5.78
134 INT125187 Positive_regulation of Transcription of Trpv1 9 0.69 8.98 5.77
135 INT109577 Positive_regulation of Gene_expression of Accn3 9 0.67 4.77 5.76
136 INT67693 Binding of Grin2a 9 0.38 1.74 5.68
137 INT93165 Gene_expression of TRPV2 32 0.78 12.49 5.62
138 INT135473 Negative_regulation of Gene_expression of Grin1 14 0.47 5.47 5.36
139 INT127353 Regulation of Phosphorylation of Grin2b 5 0.45 1.6 5.29
140 INT130478 Localization of Grin2b 11 0.75 2.49 5.28
141 INT208108 Localization of Grin2a 19 0.70 1.5 5.22
142 INT114627 Positive_regulation of Gene_expression of Trpv2 9 0.70 6.41 5.18
143 INT92541 Localization of Grin2b 11 0.75 2.85 5.14
144 INT19549 Binding of Grin2a 12 0.45 1.24 5.09
145 INT140799 Positive_regulation of Gene_expression of Accn3 6 0.68 5.44 5.06
146 INT94357 Positive_regulation of Transcription of Trpv1 11 0.50 3.63 5.05
147 INT105216 Positive_regulation of Trpv2 9 0.61 4.12 4.93
148 INT71759 Positive_regulation of P2RX1 13 0.67 3.53 4.9
149 INT135474 Negative_regulation of Gene_expression of Grin2a 7 0.39 6.94 4.89
150 INT156296 Regulation of Trpv4 20 0.45 7.84 4.86
151 INT111947 Positive_regulation of Gene_expression of Grin2a 7 0.68 1.75 4.84
152 INT93192 Transcription of Accn2 5 0.52 4.63 4.79
153 INT160437 Gene_expression of Trpc6 24 0.78 9.09 4.75
154 INT134610 Positive_regulation of Phosphorylation of Trpv1 9 0.69 4.51 4.74
155 INT81086 Positive_regulation of Accn1 8 0.65 7.51 4.62
156 INT79505 Binding of Grin2b 9 0.36 1.43 4.61
157 INT93035 Negative_regulation of Transcription of Grin1 6 0.41 2.29 4.39
158 INT15851 Positive_regulation of Trpv3 11 0.60 4.6 4.35
159 INT100125 Negative_regulation of Accn3 11 0.59 5.85 4.32
160 INT111404 Regulation of Positive_regulation of Grin1 5 0.56 2.49 4.31
161 INT81250 Transcription of Trpv2 7 0.64 1.54 4.27
162 INT170348 Regulation of Gene_expression of Grin2b 8 0.60 2.29 4.25
163 INT112100 Negative_regulation of Gene_expression of Grin2b 6 0.42 3.71 4.24
164 INT144396 Positive_regulation of P2rx1 11 0.49 3.25 4.23
165 INT77515 Positive_regulation of ASIC3 12 0.67 3.67 4.19
166 INT31762 Gene_expression of Itpr3 22 0.74 1.6 4.15
167 INT115354 Regulation of Binding of Grin1 2 0.43 1.15 4.08
168 INT102850 Gene_expression of Trpv3 12 0.56 2.06 4.01
169 INT109821 Negative_regulation of Trpv4 19 0.55 6.86 3.98
170 INT124028 Localization of Trpv2 6 0.80 2.04 3.96
171 INT103999 Positive_regulation of Phosphorylation of Grin2a 5 0.38 3.12 3.94
172 INT95171 Binding of P2rx1 12 0.36 4.69 3.92
173 INT147028 Negative_regulation of Accn2 6 0.14 2.06 3.92
174 INT163500 Transcription of Grin2b 3 0.67 3.63 3.8
175 INT92516 Positive_regulation of Gene_expression of Grin1 8 0.45 2.53 3.77
176 INT139646 Positive_regulation of Positive_regulation of Grin2b 4 0.42 3.89 3.74
177 INT84593 Positive_regulation of Binding of Grin1 6 0.48 2.74 3.72
178 INT121986 Phosphorylation of Grin2a 5 0.76 0.83 3.71
179 INT64203 Positive_regulation of Negative_regulation of Trpv1 5 0.47 3.39 3.67
180 INT141253 Regulation of Transcription of Trpv1 7 0.62 3.54 3.62
181 INT817 Negative_regulation of Abp1 15 0.49 4.25 3.56
182 INT209221 Regulation of Gene_expression of Grin2a 5 0.24 2.81 3.45
183 INT132888 Negative_regulation of Phosphorylation of Grin1 3 0.57 1.18 3.43
184 INT231293 Negative_regulation of Grin2d 4 0.45 3.95 3.38
185 INT102276 Gene_expression of Grin2d 10 0.71 4.74 3.37
186 INT181496 Regulation of TRPV4 3 0.23 3.32 3.23
187 INT58063 Negative_regulation of Binding of Trpv1 6 0.59 1.54 3.21
188 INT72256 Binding of Accn3 6 0.47 2.01 3.2
189 INT138350 Regulation of Phosphorylation of Trpv1 6 0.58 1.87 3.16
190 INT112175 Negative_regulation of Gene_expression of Trpv4 8 0.59 3.7 3.12
191 INT54999 Regulation of Itpr3 6 0.24 0.18 3.11
192 INT132887 Positive_regulation of Phosphorylation of Grin1 3 0.49 1.73 3.08
193 INT101368 Positive_regulation of Gene_expression of ASIC3 6 0.32 2.61 3.06
194 INT9569 Negative_regulation of Trpv3 6 0.40 0.84 3.03
195 INT165084 Transcription of Accn3 3 0.70 3.4 3.01
196 INT90611 Positive_regulation of Positive_regulation of Grin2a 4 0.63 1.89 3
197 INT196872 Negative_regulation of Localization of Trpv1 4 0.42 1.47 2.98
198 INT276842 Positive_regulation of Transcription of Accn3 2 0.49 3.32 2.93
199 INT114263 Negative_regulation of Negative_regulation of Trpv1 6 0.43 2.71 2.92
200 INT26833 Negative_regulation of P2rx1 9 0.41 1.5 2.89
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