GO:0005313

From wiki-pain
Jump to: navigation, search
Name L-glutamate transmembrane transporter activity
Categary Function
Go Slim No
Go Link GO:0005313
Unique Molecular Interactions 68
Total Molecular Interactions 88
Total Single Events 1113
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for L-glutamate transmembrane transporter activity. They are ordered first by their pain relevance and then by number of times they were reported for L-glutamate transmembrane transporter activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT142527 Binding of Slc1a2 and Slc1a3 2 0.31 0.12 2.13
2 INT352464 Gse1 Positive_regulation of Gene_expression of Slc1a3 1 0.05 1.55 1.83
3 INT187805 Ms18 Regulation of Positive_regulation of Slc1a3 1 0.26 0.87 1.12
4 INT250253 Binding of AQP4 and SLC1A2 1 0.30 2.95 1.09
5 INT250248 Binding of AQP4 and SLC1A3 1 0.11 1.55 0.77
6 INT128275 Slc17a7 Positive_regulation of Transcription of Slc17a6 1 0.39 0.27 0.63
7 INT311766 INCENP Negative_regulation of Gene_expression of SLC1A3 1 0.04 0 0.55
8 INT311767 INS Negative_regulation of Gene_expression of SLC1A3 1 0.52 0 0.52
9 INT132242 NR3C1 Regulation of Gene_expression of Slc1a1 1 0.09 0.62 0.49
10 INT291384 Cntf Positive_regulation of Slc1a3 1 0.26 0.34 0.45
11 INT250251 Binding of SLC1A2 and SLC1A3 1 0.09 1.12 0.43
12 INT282505 Binding of ocd and Slc1a1 1 0.39 4.22 0.4
13 INT250250 Gene_expression of AQP4 Positive_regulation of Gene_expression of SLC1A2 1 0.37 1.1 0.39
14 INT64639 Slc1a1 Positive_regulation of Ddc 1 0.30 0.3 0.38
15 INT250252 Binding of SLC1A2 and GOPC 1 0.05 0.44 0.35
16 INT250254 Binding of SLC1A3 and GOPC 1 0.02 0.44 0.35
17 INT352461 Calca Regulation of Gene_expression of Slc1a3 1 0.03 0 0.27
18 INT352451 Gse1 Regulation of Slc1a3 1 0.01 0 0.27
19 INT352455 Gse1 Regulation of Gene_expression of Slc1a3 1 0.04 0 0.27
20 INT352449 Dusp1 Regulation of Gene_expression of Slc1a3 1 0.05 0 0.27
21 INT305504 Slc17a6 Positive_regulation of Ex 1 0.05 0.67 0.22
22 INT305505 Negative_regulation of Binding of Igfals and Slc17a6 1 0.16 1.12 0.21
23 INT305510 Binding of Igfals and Slc17a6 1 0.14 1.11 0.21
24 INT305508 Binding of Sod1 and Slc17a6 1 0.03 1.1 0.2
25 INT305511 Negative_regulation of Binding of Sod1 and Slc17a6 1 0.03 1.1 0.2
26 INT250241 SLC1A3 Positive_regulation of AQP4 1 0.13 0.21 0.16
27 INT250246 SLC1A2 Positive_regulation of AQP4 1 0.13 0.22 0.16
28 INT268733 Slc1a3 Regulation of Binding of Slc1a2 1 0.39 0.23 0.14
29 INT268735 Slc1a2 Regulation of Binding of Slc1a3 1 0.39 0.23 0.14
30 INT305506 Binding of Pgk1 and Slc17a6 1 0.04 0.31 0.11
31 INT251231 Binding of Syp and Slc17a6 1 0.04 0 0.08
32 INT305503 Binding of Nr5a1 and Slc17a6 1 0.08 0.37 0.08
33 INT251232 Slc17a6 Positive_regulation of Tgfb1 1 0.03 0 0.08
34 INT250249 Binding of SLC1A2 and Positive_regulation of SLC1A3 1 0.12 0.69 0.08
35 INT250244 Binding of AQP4 and Positive_regulation of SLC1A3 1 0.14 0.69 0.08
36 INT198079 Ass1 Positive_regulation of Gene_expression of Slc1a3 1 0.01 0 0.07
37 INT250243 FCGR3A Regulation of Gene_expression of SLC1A2 1 0.00 0.78 0.06
38 INT250245 Binding of FCGR3A and SLC1A3 1 0.00 0.18 0.05
39 INT314395 Binding of Gpsm2 and Slc17a6 1 0.20 0 0
40 INT326809 Binding of Ankrd36 and SLC25A22 1 0.10 0.13 0
41 INT282502 Negative_regulation of Binding of ocd and Slc1a1 1 0.30 0.48 0
42 INT314399 Binding of Slc17a7 and Slc17a6 1 0.14 0 0
43 INT314396 Binding of Ptpn6 and Slc17a6 1 0.05 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for L-glutamate transmembrane transporter activity. They are ordered first by their pain relevance and then by number of times they were reported in L-glutamate transmembrane transporter activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT96533 Gene_expression of Slc1a3 72 0.78 26.85 55.31
2 INT127013 Negative_regulation of Slc1a3 37 0.54 14.16 43.97
3 INT99538 Gene_expression of Slc1a1 26 0.75 9.3 21.57
4 INT135673 Positive_regulation of Slc1a3 23 0.57 5.45 21.45
5 INT107928 Gene_expression of Slc17a6 34 0.76 3.76 16.64
6 INT128013 Negative_regulation of Gene_expression of Slc1a3 20 0.59 10.65 16.13
7 INT98109 Regulation of Slc1a3 15 0.52 6.87 14.43
8 INT105194 Negative_regulation of Slc1a1 11 0.56 3.05 14.19
9 INT135674 Positive_regulation of Gene_expression of Slc1a3 11 0.62 5.21 13.61
10 INT182574 Localization of Slc1a3 10 0.73 5.47 11.44
11 INT139935 Gene_expression of Slc17a6 36 0.78 8.43 10.61
12 INT53063 Positive_regulation of Slc1a1 10 0.70 3.23 9.89
13 INT179753 Gene_expression of SLC1A2 28 0.59 13.72 8.71
14 INT155680 Gene_expression of Slc1a3 22 0.66 6.76 7.23
15 INT127014 Negative_regulation of Negative_regulation of Slc1a3 6 0.54 2.11 6.98
16 INT179744 Negative_regulation of SLC1A2 16 0.45 12.32 6.14
17 INT136153 Binding of Slc1a3 7 0.40 2.71 6.01
18 INT135675 Positive_regulation of Negative_regulation of Slc1a3 4 0.45 0.38 5.87
19 INT135672 Negative_regulation of Positive_regulation of Slc1a3 4 0.38 0.33 5.49
20 INT165460 Gene_expression of SLC1A3 15 0.75 7.19 5.43
21 INT139933 Negative_regulation of Slc17a6 3 0.59 10.25 5.43
22 INT99536 Regulation of Gene_expression of Slc1a3 6 0.60 1.76 5.04
23 INT155681 Negative_regulation of Gene_expression of Slc1a3 5 0.36 2.26 4.86
24 INT132237 Negative_regulation of Gene_expression of Slc1a1 4 0.56 2.05 4.45
25 INT107586 Transcription of Slc17a6 6 0.61 0.79 3.68
26 INT267678 Positive_regulation of Positive_regulation of Slc1a1 1 0.07 1.34 3.65
27 INT105195 Positive_regulation of Negative_regulation of Slc1a1 2 0.40 0.48 3.4
28 INT124921 Negative_regulation of Negative_regulation of Slc1a1 3 0.56 0.67 3.36
29 INT132239 Localization of Slc1a1 4 0.77 1.93 3.27
30 INT187803 Negative_regulation of Localization of Slc1a3 1 0.23 1.24 3.2
31 INT198076 Gene_expression of Slc1a1 13 0.73 2.41 3.07
32 INT179756 Positive_regulation of Gene_expression of SLC1A2 8 0.38 2.95 3.06
33 INT106919 Regulation of Slc17a6 8 0.42 0.88 3.02
34 INT132240 Positive_regulation of Gene_expression of Slc1a1 2 0.66 0.62 2.96
35 INT155685 Regulation of Gene_expression of Slc1a3 2 0.50 0.77 2.85
36 INT153997 Negative_regulation of Gene_expression of Slc17a6 2 0.59 3.01 2.42
37 INT126033 Localization of Slc17a6 4 0.77 0.75 2.35
38 INT250283 Positive_regulation of SLC1A2 5 0.53 3.22 2.29
39 INT195110 Positive_regulation of Gene_expression of Slc1a3 5 0.44 2.88 2.27
40 INT139932 Regulation of Slc17a6 4 0.45 2.21 2.17
41 INT179750 Negative_regulation of Gene_expression of SLC1A2 3 0.45 3.05 2.15
42 INT128272 Positive_regulation of Gene_expression of Slc17a6 3 0.47 0.66 2.03
43 INT99534 Regulation of Gene_expression of Slc1a1 2 0.48 1.67 2.01
44 INT179749 Regulation of SLC1A2 3 0.34 2.28 1.99
45 INT127053 Transcription of Slc1a3 4 0.43 0.8 1.9
46 INT137518 Regulation of Slc1a1 2 0.47 0.74 1.82
47 INT165459 Positive_regulation of SLC1A3 3 0.49 1.08 1.73
48 INT137519 Binding of Slc1a1 2 0.29 0.68 1.7
49 INT151270 Positive_regulation of Positive_regulation of Slc1a3 1 0.57 0 1.69
50 INT198066 Negative_regulation of Slc1a3 2 0.41 1.25 1.68
51 INT138294 Regulation of Negative_regulation of Slc1a3 1 0.29 0.17 1.62
52 INT155829 Negative_regulation of Protein_catabolism of Slc1a3 1 0.34 0.1 1.6
53 INT155828 Protein_catabolism of Slc1a3 1 0.80 0.1 1.6
54 INT165457 Negative_regulation of SLC1A3 3 0.42 1.46 1.56
55 INT179752 Positive_regulation of Gene_expression of SLC1A3 3 0.17 2.35 1.56
56 INT56439 Regulation of Positive_regulation of Slc1a1 3 0.32 1.65 1.47
57 INT305492 Negative_regulation of Localization of Slc17a6 3 0.43 1.49 1.45
58 INT305490 Transcription of Slc17a6 5 0.72 0.43 1.44
59 INT305497 Localization of Slc17a6 4 0.75 1.48 1.42
60 INT305494 Positive_regulation of Slc17a6 1 0.50 2.3 1.34
61 INT179754 Regulation of Gene_expression of SLC1A2 3 0.34 0.93 1.32
62 INT187801 Negative_regulation of Binding of Slc1a3 1 0.26 0.25 1.26
63 INT251225 Binding of Slc17a6 2 0.37 1.9 1.1
64 INT165458 Regulation of Gene_expression of SLC1A3 1 0.23 0.26 1.08
65 INT187804 Positive_regulation of Localization of Slc1a3 1 0.26 0.84 1.06
66 INT179751 Negative_regulation of Gene_expression of SLC1A3 1 0.19 0.75 1.05
67 INT198074 Positive_regulation of Gene_expression of Slc1a1 2 0.65 0.25 0.89
68 INT127051 Positive_regulation of Transcription of Slc1a3 2 0.14 0.37 0.89
69 INT191831 Positive_regulation of Slc1a3 6 0.49 3.66 0.87
70 INT305495 Positive_regulation of Regulation of Slc17a6 1 0.47 1.72 0.83
71 INT139931 Regulation of Gene_expression of Slc17a6 1 0.62 0.39 0.83
72 INT106920 Positive_regulation of Slc17a6 2 0.47 0.15 0.82
73 INT352657 Transcription of SLC1A2 1 0.06 0.76 0.8
74 INT352660 Transcription of SLC1A3 1 0.05 0.76 0.8
75 INT198064 Negative_regulation of Gene_expression of Slc1a1 1 0.39 0.26 0.76
76 INT179748 Regulation of SLC1A3 1 0.15 0.09 0.66
77 INT305498 Positive_regulation of Gene_expression of Slc17a6 1 0.50 1.13 0.54
78 INT319282 Positive_regulation of Slc1a1 1 0.43 0.17 0.5
79 INT319255 Positive_regulation of Transcription of Slc1a1 1 0.65 0.17 0.48
80 INT319272 Transcription of Slc1a1 1 0.67 0.16 0.47
81 INT305486 Negative_regulation of Transcription of Slc17a6 1 0.43 0 0.46
82 INT250276 Localization of SLC1A2 1 0.61 2.4 0.44
83 INT352656 Positive_regulation of Transcription of SLC1A2 1 0.04 0.39 0.43
84 INT352659 Positive_regulation of Transcription of SLC1A3 1 0.04 0.39 0.43
85 INT198072 Positive_regulation of Localization of Slc1a1 1 0.40 0.1 0.39
86 INT198070 Localization of Slc1a1 1 0.63 0.1 0.39
87 INT198078 Positive_regulation of Negative_regulation of Slc1a3 1 0.40 0.15 0.38
88 INT351825 Gene_expression of SLC25A22 1 0.19 2.02 0.38
89 INT116167 Negative_regulation of Gene_expression of Slc17a6 1 0.42 0.06 0.38
90 INT150431 Regulation of Transcription of Slc1a3 1 0.10 0.33 0.37
91 INT198069 Regulation of Gene_expression of Slc1a1 1 0.56 0.12 0.36
92 INT198071 Regulation of Slc1a3 1 0.36 0.08 0.35
93 INT148625 Regulation of Transcription of Slc17a6 1 0.18 0.07 0.27
94 INT106918 Negative_regulation of Slc17a6 1 0.24 0 0.27
95 INT148624 Regulation of Gene_expression of Slc17a6 1 0.31 0.07 0.27
96 INT250277 Regulation of Localization of SLC1A2 1 0.34 0.99 0.25
97 INT250278 Binding of SLC1A2 1 0.28 1.52 0.24
98 INT305487 Positive_regulation of Negative_regulation of Slc17a6 1 0.61 0.87 0.21
99 INT198077 Regulation of Slc1a1 1 0.24 0.07 0.18
100 INT206487 Binding of SLC1A3 2 0.36 0.21 0.17
101 INT198075 Binding of Slc1a1 2 0.35 1.02 0.14
102 INT270125 Transcription of Slc1a1 1 0.10 1.76 0.09
103 INT198065 Binding of Slc1a3 3 0.30 0 0.05
104 INT277525 Transcription of Slc1a3 1 0.59 0.09 0.05
105 INT250271 Localization of SLC1A3 1 0.20 0.77 0.04
106 INT270126 Positive_regulation of Transcription of Slc1a1 1 0.10 0.8 0.04
107 INT250268 Regulation of Localization of SLC1A3 1 0.12 0.77 0.04
108 INT253781 Binding of Slc17a6 1 0.03 0 0
109 INT326806 Binding of SLC25A22 1 0.09 0.13 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox