GO:0005384

From wiki-pain
Jump to: navigation, search
Name manganese ion transmembrane transporter activity
Categary Function
Go Slim No
Go Link GO:0005384
Unique Molecular Interactions 28
Total Molecular Interactions 35
Total Single Events 190
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for manganese ion transmembrane transporter activity. They are ordered first by their pain relevance and then by number of times they were reported for manganese ion transmembrane transporter activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT209043 Binding of Fn1 and Slc11a1 3 0.03 1.91 0.78
2 INT209063 Slc11a1 Positive_regulation of Il17a 1 0.11 0.4 0.65
3 INT209046 Slc11a1 Positive_regulation of Regulation of Tlr4 1 0.07 0.09 0.48
4 INT209049 Slc11a1 Positive_regulation of Localization of Il12a 1 0.04 0.09 0.44
5 INT209047 Slc11a1 Positive_regulation of Localization of Il10 1 0.10 0.52 0.36
6 INT272412 VSX1 Positive_regulation of Gene_expression of Slc11a1 1 0.00 0.57 0.35
7 INT262809 Il10 Positive_regulation of Regulation of Slc11a1 1 0.17 1.12 0.27
8 INT262810 Slc11a1 Positive_regulation of Gene_expression of Il10 1 0.20 0.97 0.27
9 INT209066 Slc11a1 Positive_regulation of Binding of TNF 1 0.01 1.11 0.24
10 INT226911 Slc11a1 Positive_regulation of Gene_expression of Il6 1 0.09 1.12 0.24
11 INT276241 Slc11a1 Positive_regulation of Gene_expression of Hand1 1 0.02 1.24 0.21
12 INT178269 Slc11a2 Regulation of a 1 0.06 0.97 0.16
13 INT226901 Slc11a1 Regulation of Hist1h3f 1 0.02 0.41 0.15
14 INT204159 Slc11a2 Regulation of Gene_expression of HAMP 1 0.11 1.08 0.14
15 INT288701 Epas1 Regulation of Transcription of Slc11a2 1 0.29 0.38 0.13
16 INT226899 Slc11a1 Positive_regulation of Localization of Gtf3a 1 0.00 0.54 0.11
17 INT226910 Slc11a1 Positive_regulation of Localization of Nfkb1 1 0.11 0.62 0.11
18 INT226912 Slc11a1 Positive_regulation of Localization of IL8 1 0.05 0.58 0.08
19 INT226913 Slc11a1 Positive_regulation of Gene_expression of IL8 1 0.05 0.63 0.07
20 INT226897 Binding of Slc11a1 and Tg(CAG-EGFP)D4Nagy 1 0.01 0.17 0.04
21 INT226905 Slc11a1 Regulation of Nfkb1 1 0.04 0.41 0.03
22 INT253850 Binding of TRPM2 and Ssr1 1 0.02 0 0
23 INT272441 Binding of IFNA2 and Slc11a1 1 0.02 0.97 0
24 INT221113 Slc11a1 Negative_regulation of Upk1b 1 0.19 0.37 0
25 INT226896 Slc11a1 Positive_regulation of Binding of Nfkb1 1 0.11 0.08 0
26 INT221114 Slc11a1 Negative_regulation of Upk1a 1 0.23 0.37 0
27 INT226909 Positive_regulation of Binding of Nfkb1 and Slc11a1 1 0.07 0.18 0
28 INT226898 Binding of Nfkb1 and Slc11a1 1 0.06 0.2 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for manganese ion transmembrane transporter activity. They are ordered first by their pain relevance and then by number of times they were reported in manganese ion transmembrane transporter activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT88245 Gene_expression of Slc11a1 42 0.53 18.86 6.2
2 INT209018 Positive_regulation of Slc11a1 11 0.55 7.12 3.83
3 INT209019 Localization of Slc11a1 12 0.33 4.33 2.33
4 INT209027 Positive_regulation of Positive_regulation of Slc11a1 3 0.14 2.41 2.18
5 INT96841 Regulation of Slc11a1 9 0.36 6.83 2.14
6 INT96842 Binding of Slc11a1 16 0.34 7.15 1.66
7 INT142274 Gene_expression of TRPM2 7 0.78 2.29 1.31
8 INT132883 Gene_expression of Slc11a2 5 0.75 2.96 0.89
9 INT142276 Positive_regulation of Gene_expression of TRPM2 1 0.70 1.26 0.74
10 INT142277 Positive_regulation of TRPM2 7 0.70 1 0.69
11 INT221108 Negative_regulation of Slc11a1 5 0.33 3.76 0.69
12 INT209023 Positive_regulation of Gene_expression of Slc11a1 3 0.22 1.19 0.6
13 INT209015 Positive_regulation of Localization of Slc11a1 1 0.14 0.45 0.54
14 INT209020 Negative_regulation of Gene_expression of Slc11a1 3 0.16 0.78 0.49
15 INT187778 Gene_expression of Slc11a1 12 0.33 7.37 0.35
16 INT11941 Binding of Slc11a1 3 0.14 2.18 0.35
17 INT164126 Negative_regulation of TRPM2 2 0.42 0 0.32
18 INT226881 Regulation of Positive_regulation of Slc11a1 1 0.09 0.95 0.32
19 INT142275 Negative_regulation of Gene_expression of TRPM2 1 0.43 0.43 0.27
20 INT164125 Binding of TRPM2 4 0.36 0.15 0.2
21 INT204148 Regulation of Gene_expression of Slc11a2 1 0.15 1.1 0.15
22 INT288681 Regulation of Transcription of Slc11a2 1 0.44 0.37 0.13
23 INT288683 Transcription of Slc11a2 1 0.69 0.37 0.13
24 INT288682 Binding of Slc11a2 1 0.47 0 0.12
25 INT309757 Negative_regulation of Positive_regulation of TRPM2 1 0.16 0 0.1
26 INT249254 Regulation of TRPM2 1 0.33 0.16 0.04
27 INT187781 Positive_regulation of Slc11a1 3 0.24 1.76 0
28 INT187780 Localization of Slc11a1 2 0.28 0.9 0
29 INT221110 Regulation of Regulation of Slc11a1 1 0.35 0.22 0
30 INT262807 Positive_regulation of Transcription of Slc11a1 1 0.19 0.08 0
31 INT187779 Regulation of Slc11a1 1 0.10 0.75 0
32 INT187777 Positive_regulation of Localization of Slc11a1 1 0.19 0.27 0
33 INT262808 Transcription of Slc11a1 1 0.26 0.08 0
34 INT272440 Negative_regulation of Slc11a1 1 0.02 0.81 0
35 INT226886 Regulation of Binding of Slc11a1 1 0.09 0.15 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox