GO:0005497

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Name androgen binding
Categary Function
Go Slim No
Go Link GO:0005497
Unique Molecular Interactions 152
Total Molecular Interactions 209
Total Single Events 1747
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for androgen binding. They are ordered first by their pain relevance and then by number of times they were reported for androgen binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69279 Regulation of Binding of TSPO and Gabrg1 1 0.00 2.05 1.26
2 INT99695 Binding of Tspo and Insrr 1 0.02 0.52 1.25
3 INT59606 Binding of Tspo and Penk 1 0.04 0 1.12
4 INT238092 Binding of SHBG and Mmp24 1 0.04 0 0.98
5 INT310348 Binding of Tspo and Gabrd 1 0.00 0.43 0.88
6 INT137699 AR Regulation of PDYN 1 0.46 0.93 0.75
7 INT226308 CHPT1 Positive_regulation of Localization of SHBG 1 0.09 0.65 0.64
8 INT69280 Negative_regulation of Binding of TSPO and Gabrg1 1 0.00 1.03 0.63
9 INT69278 Binding of TSPO and Gabrg1 1 0.00 1.01 0.62
10 INT57391 Binding of Tspo and Oprl1 1 0.18 0.16 0.49
11 INT185917 Binding of AR and MAPK1 1 0.07 0.5 0.47
12 INT252425 Positive_regulation of AR Positive_regulation of Gene_expression of CXCL10 1 0.00 0.9 0.44
13 INT244280 Binding of Tspo and Ptz1a 1 0.02 0.49 0.41
14 INT139047 Negative_regulation of AR Negative_regulation of Positive_regulation of CPOX 1 0.07 0.76 0.4
15 INT226072 Binding of MMP9 and SHBG 1 0.15 1.02 0.39
16 INT52632 Binding of TSPO and CCK 1 0.15 0.53 0.37
17 INT240616 Binding of SHBG and ADIPOQ 1 0.31 4.43 0.37
18 INT252453 Binding of AR and Adora2b 1 0.05 0 0.35
19 INT75641 AR Positive_regulation of Positive_regulation of EIF2B3 1 0.02 0 0.33
20 INT349664 PYCARD Negative_regulation of Localization of AR 1 0.05 0 0.32
21 INT284689 Binding of Tspo and Map3k12 1 0.00 0.59 0.32
22 INT349662 Binding of PYCARD and Negative_regulation of Localization of AR 1 0.05 0 0.32
23 INT84426 Binding of TSPO and INSRR 1 0.01 0.22 0.3
24 INT158922 Positive_regulation of Binding of TSPO and Tspo 1 0.54 0.83 0.28
25 INT158923 Binding of TSPO and Tspo 1 0.40 0.82 0.28
26 INT223042 AR Positive_regulation of ADCY1 1 0.01 0.41 0.25
27 INT226073 Binding of CRP and SHBG 2 0.10 2.14 0.24
28 INT257776 Phosphorylation of AR Positive_regulation of Localization of TAB2 1 0.26 0.38 0.24
29 INT252427 IGKV2D-29 Regulation of Gene_expression of AR 1 0.02 0 0.24
30 INT139046 Negative_regulation of AR Negative_regulation of Phosphorylation of DYT10 1 0.33 0.34 0.23
31 INT139050 Negative_regulation of AR Negative_regulation of Phosphorylation of PRKCB 1 0.02 0.34 0.23
32 INT139045 Negative_regulation of AR Negative_regulation of CPOX 1 0.07 0.34 0.23
33 INT139048 Negative_regulation of AR Negative_regulation of Positive_regulation of TRAF3IP2 1 0.02 0.34 0.23
34 INT139049 Negative_regulation of AR Negative_regulation of Positive_regulation of DYT10 1 0.33 0.34 0.23
35 INT198382 Binding of AR and SRD5A1 2 0.06 0.84 0.17
36 INT191336 Binding of TSPO and GOPC 1 0.01 0.65 0.16
37 INT191338 Binding of TSPO and IDO1 1 0.02 0.65 0.16
38 INT122361 Binding of AR and OPRM1 1 0.26 0.14 0.16
39 INT240620 Binding of INS and SHBG 4 0.12 3.35 0.15
40 INT122362 AR Positive_regulation of Positive_regulation of OPRM1 1 0.32 0.19 0.14
41 INT197645 DPH1 Positive_regulation of SHBG 1 0.02 0.06 0.14
42 INT209645 AR Regulation of STUB1 1 0.04 0.93 0.13
43 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
44 INT169128 Trove2 Negative_regulation of Gene_expression of AR 1 0.05 0.94 0.13
45 INT223040 AR Positive_regulation of Negative_regulation of TFPI 1 0.03 0 0.13
46 INT354620 AR Positive_regulation of Hspg2 1 0.00 0 0.12
47 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12
48 INT185918 AR Positive_regulation of Gene_expression of NOS2 1 0.12 0.21 0.11
49 INT220743 Binding of AR and EGFR 1 0.01 0.46 0.1
50 INT251469 INS Negative_regulation of Gene_expression of SHBG 2 0.11 4.11 0.08
51 INT178434 Il6 Positive_regulation of Ar 1 0.01 0.93 0.08
52 INT257777 INCENP Positive_regulation of AR 1 0.04 0.49 0.08
53 INT287174 Binding of PGR and SHBG 1 0.18 0.11 0.08
54 INT213933 AR Negative_regulation of Cyp19a1 1 0.07 0.79 0.07
55 INT224293 AR Positive_regulation of Protein_catabolism of ESR1 1 0.24 0.4 0.07
56 INT328380 AR Negative_regulation of Gene_expression of Ghrl 1 0.01 0.55 0.07
57 INT293813 ERBB2 Positive_regulation of Positive_regulation of AR 1 0.09 0.45 0.07
58 INT201866 Binding of AR and PGR 1 0.07 0.34 0.06
59 INT338019 Egf Positive_regulation of AR 1 0.07 1.02 0.05
60 INT349665 Positive_regulation of Binding of AR and TFPI 1 0.02 0 0.05
61 INT349667 Binding of AR and TFPI 1 0.02 0 0.05
62 INT209644 Binding of AR and C4B 1 0.00 0.32 0.04
63 INT178441 Binding of Ar and Sra1 1 0.00 0.45 0.04
64 INT213383 Srd5a3 Negative_regulation of Gene_expression of AR 1 0.01 0.7 0.04
65 INT319384 Binding of AR and SCGB2A2 1 0.01 1.36 0.04
66 INT350121 INS Negative_regulation of Positive_regulation of SHBG 1 0.09 1.48 0.04
67 INT350118 INS Negative_regulation of SHBG 1 0.09 1.42 0.04
68 INT206849 ESR1 Regulation of Gene_expression of ALDH1A1 1 0.11 2.26 0.04
69 INT178439 Binding of Ar and Src 1 0.01 0.44 0.04
70 INT178428 Regulation of Il6 Positive_regulation of Ar 1 0.01 0.47 0.04
71 INT246480 Binding of ALB and SHBG 2 0.14 1.45 0.03
72 INT279632 Positive_regulation of Binding of Ar and Nr4a1 1 0.01 0.86 0.03
73 INT326736 AR Regulation of Gene_expression of ARG2 1 0.34 0.43 0.03
74 INT185651 GOPC Positive_regulation of AR 1 0.03 0.06 0.03
75 INT349661 PYCARD Positive_regulation of AR 1 0.08 0 0.03
76 INT198143 Binding of AR and ANTXR2 1 0.01 0.19 0.03
77 INT326742 AR Regulation of Gene_expression of ARG1 1 0.24 0.43 0.03
78 INT279634 Binding of Ar and Nr4a1 1 0.01 0.85 0.03
79 INT278294 Binding of ESR1 and SHBG 1 0.01 0.82 0.03
80 INT218964 Dlst Regulation of AR 1 0.01 0 0.03
81 INT187676 Binding of CYP19A1 and SHBG 1 0.01 0.63 0.03
82 INT278293 Binding of DBP and SHBG 2 0.02 1.34 0
83 INT265730 Binding of AR and VEGFA 1 0.09 0 0
84 INT338180 Binding of AR and STAT3 1 0.18 0.3 0
85 INT304020 AR Regulation of TP53 1 0.24 1.11 0
86 INT339404 Binding of Ar and Tymp 1 0.10 0.06 0
87 INT218963 Dlst Negative_regulation of AR 1 0.00 0.1 0
88 INT209636 TRPV1 Regulation of Gene_expression of AR 1 0.17 0.38 0
89 INT339403 Negative_regulation of Binding of Ar and Tymp 1 0.12 0 0
90 INT293809 MAPK1 Positive_regulation of AR 1 0.03 0.12 0
91 INT278295 DBP Positive_regulation of SHBG 1 0.02 0.92 0
92 INT209633 AR Regulation of Gene_expression of PCa 1 0.06 1.19 0
93 INT291753 ALDOA Positive_regulation of ALDH1A1 1 0.00 0 0
94 INT213365 AR Regulation of Gene_expression of VEGFA 1 0.09 1.52 0
95 INT215349 Binding of VDAC1 and Tspo 1 0.00 0.63 0
96 INT338018 Binding of AR and Flna 1 0.11 0.33 0
97 INT209634 Binding of AR and PCa 1 0.04 1.03 0
98 INT293818 AKT1 Positive_regulation of Gene_expression of AR 1 0.05 0.31 0
99 INT349666 Binding of AR and PYCARD 1 0.06 0 0
100 INT326740 Gene_expression of AR Negative_regulation of Gene_expression of ARG2 1 0.24 0.8 0
101 INT270732 DBP Negative_regulation of SHBG 1 0.00 1.08 0
102 INT209630 ALG12 Regulation of Gene_expression of AR 1 0.13 0.38 0
103 INT209635 AR Positive_regulation of ALG12 1 0.14 0.32 0
104 INT338194 Regulation of VAV3 Regulation of AR 1 0.31 0.49 0
105 INT293803 Negative_regulation of ERBB2 Negative_regulation of Gene_expression of AR 1 0.10 0 0
106 INT293819 EPHB2 Positive_regulation of AR 1 0.23 0.12 0
107 INT213176 Binding of HP and SHBG 1 0.02 1.07 0
108 INT322661 Binding of Tspo and Pbrm1 1 0.00 1.08 0
109 INT338197 CCND1 Negative_regulation of AR 1 0.24 0 0
110 INT354619 AR Positive_regulation of Gene_expression of Nppa 1 0.00 0.38 0
111 INT338022 Cuedc2 Positive_regulation of Protein_catabolism of AR 1 0.23 0.29 0
112 INT218960 Binding of AR and Esyt1 1 0.00 0 0
113 INT209637 AR Positive_regulation of TRPV1 1 0.18 0.32 0
114 INT321882 Binding of TSPO and Lm370 1 0.01 0.4 0
115 INT293625 Binding of BGLAP and SHBG 1 0.03 0.1 0
116 INT293806 AR Positive_regulation of PIK3CG 1 0.06 0.12 0
117 INT209629 AR Negative_regulation of Gene_expression of MRFAP1 1 0.26 0.16 0
118 INT185652 Binding of AR and GOPC 1 0.03 0 0
119 INT338182 CDCP1 Positive_regulation of Phosphorylation of AR 1 0.01 0.29 0
120 INT339407 Negative_regulation of Binding of AR and Tymp 1 0.04 0 0
121 INT102124 Binding of AR and ESRRB 1 0.03 0.13 0
122 INT218965 Esyt1 Negative_regulation of AR 1 0.00 0 0
123 INT209641 AR Positive_regulation of PCa 1 0.06 1.17 0
124 INT343161 ACSL4 Regulation of Gene_expression of TSPO 1 0.25 0.75 0
125 INT338021 Binding of Flna and Regulation of Transcription of AR 1 0.14 0.33 0
126 INT265737 Binding of AR and NRP1 1 0.10 0 0
127 INT326743 Gene_expression of AR Negative_regulation of Gene_expression of ARG1 1 0.32 0.8 0
128 INT209638 AR Regulation of MRFAP1 1 0.12 0.41 0
129 INT226305 SHBG Positive_regulation of Binding of CHPT1 1 0.09 0 0
130 INT339406 Binding of AR and Tymp 1 0.03 0.06 0
131 INT193147 CRAMP1L Regulation of TSPO 1 0.01 0.27 0
132 INT338023 Psma7 Positive_regulation of AR 1 0.17 0.38 0
133 INT279635 Ar Regulation of Abpe 1 0.01 1.55 0
134 INT265756 Positive_regulation of Binding of AR and NRP1 1 0.10 0 0
135 INT293816 Binding of AR and PIK3CG 1 0.03 0.27 0
136 INT198110 Ar Positive_regulation of Gene_expression of Aqp9 1 0.13 0 0
137 INT206843 Binding of ALDH1A1 and ESR1 1 0.07 0 0
138 INT343156 Binding of TSPO and DBI 1 0.04 0.63 0
139 INT218962 Dlst Regulation of Gene_expression of AR 1 0.01 0 0
140 INT185654 DBT Negative_regulation of AR 1 0.02 0.09 0
141 INT338020 Binding of AR and Ddr1 1 0.03 0.45 0
142 INT279633 Binding of Ar and Abpe 1 0.01 0.99 0
143 INT293810 Binding of AR and RORC 1 0.01 0.13 0
144 INT219502 TSPO Positive_regulation of Positive_regulation of Ppib 1 0.01 0 0
145 INT338185 VAV3 Regulation of Positive_regulation of AR 1 0.19 0.49 0
146 INT338193 VAV3 Regulation of AR 1 0.31 0.49 0
147 INT209643 AR Positive_regulation of PYCR1 1 0.31 1.17 0
148 INT213364 AR Regulation of VEGFA 1 0.09 0.68 0
149 INT219424 Binding of AHR and TSPO 1 0.01 0 0
150 INT117173 OCM Regulation of Transcription of AR 1 0.18 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for androgen binding. They are ordered first by their pain relevance and then by number of times they were reported in androgen binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5206 Gene_expression of AR 316 0.78 113.83 27.29
2 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66
3 INT18088 Binding of Tspo 26 0.48 9.12 10.2
4 INT424 Positive_regulation of TSPO 34 0.61 15.04 10.02
5 INT35366 Binding of AR 87 0.47 30.52 8.9
6 INT39170 Gene_expression of TSPO 76 0.78 24.11 8.05
7 INT6335 Binding of TSPO 39 0.44 10.88 7.66
8 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61
9 INT14258 Regulation of TSPO 32 0.60 10.16 6.24
10 INT4144 Gene_expression of SHBG 64 0.68 39.94 6.08
11 INT99091 Regulation of AR 70 0.45 31.68 5.05
12 INT16051 Regulation of Tspo 6 0.45 2.81 4.95
13 INT8340 Negative_regulation of SHBG 49 0.57 35.96 4.73
14 INT4146 Binding of SHBG 49 0.47 31 4.71
15 INT5205 Localization of AR 43 0.80 12.87 4.63
16 INT84727 Negative_regulation of Gene_expression of AR 38 0.58 12.46 4.63
17 INT29809 Gene_expression of Tspo 8 0.75 4.12 4.54
18 INT7841 Gene_expression of Tspo 10 0.75 7.63 4.45
19 INT6881 Binding of Tspo 12 0.46 5.03 4.38
20 INT28546 Regulation of SHBG 23 0.54 16.35 3.88
21 INT34720 Positive_regulation of SHBG 58 0.69 32.4 3.83
22 INT84427 Positive_regulation of Gene_expression of TSPO 15 0.64 5.05 3.58
23 INT5204 Positive_regulation of Gene_expression of AR 60 0.67 23.54 3.53
24 INT36716 Positive_regulation of Gene_expression of Tspo 4 0.68 3.48 3.49
25 INT25745 Regulation of Tspo 6 0.45 0.25 3.1
26 INT185927 Positive_regulation of Positive_regulation of AR 12 0.34 6.35 2.5
27 INT74131 Positive_regulation of Tspo 7 0.50 0.92 2.11
28 INT14257 Localization of TSPO 9 0.73 1.48 1.87
29 INT19576 Negative_regulation of Tspo 3 0.42 1.02 1.75
30 INT84722 Regulation of Gene_expression of AR 20 0.61 7.73 1.69
31 INT6391 Positive_regulation of Tspo 2 0.50 0.93 1.63
32 INT10598 Gene_expression of Ar 10 0.64 3.44 1.61
33 INT15969 Negative_regulation of Ar 11 0.43 2.77 1.59
34 INT82932 Transcription of AR 14 0.67 5.75 1.34
35 INT68500 Regulation of Ar 6 0.27 4.16 1.32
36 INT19635 Localization of SHBG 7 0.78 2.83 1.29
37 INT213379 Phosphorylation of AR 6 0.63 2.03 1.21
38 INT209679 Positive_regulation of Regulation of AR 3 0.37 1.88 0.96
39 INT284686 Positive_regulation of Gene_expression of Tspo 1 0.66 2.55 0.9
40 INT6806 Localization of Tspo 3 0.70 0 0.82
41 INT156529 Positive_regulation of Gene_expression of Ar 1 0.05 0.09 0.8
42 INT125782 Positive_regulation of Binding of Tspo 1 0.67 1.51 0.79
43 INT125781 Negative_regulation of Binding of Tspo 2 0.41 1.21 0.74
44 INT185669 Positive_regulation of Localization of AR 7 0.33 1.83 0.73
45 INT69003 Negative_regulation of Binding of TSPO 4 0.03 2.78 0.69
46 INT156060 Regulation of Binding of AR 2 0.09 0.42 0.69
47 INT21342 Negative_regulation of Tspo 1 0.11 0 0.68
48 INT191341 Negative_regulation of Gene_expression of TSPO 3 0.34 1.66 0.64
49 INT163859 Negative_regulation of Gene_expression of Tspo 1 0.41 0.17 0.64
50 INT73850 Transcription of TSPO 6 0.59 0.83 0.61
51 INT17493 Binding of Ar 14 0.48 3.62 0.6
52 INT204138 Regulation of Gene_expression of TSPO 2 0.36 0.99 0.6
53 INT120054 Regulation of Gene_expression of Tspo 2 0.44 0.97 0.59
54 INT49343 Positive_regulation of Ar 8 0.42 4.38 0.58
55 INT32232 Negative_regulation of Localization of SHBG 2 0.25 0.19 0.58
56 INT178718 Phosphorylation of TSPO 1 0.79 0.91 0.56
57 INT178717 Negative_regulation of Localization of TSPO 1 0.41 0.92 0.56
58 INT73849 Negative_regulation of TSPO 8 0.59 2.4 0.53
59 INT197662 Negative_regulation of Positive_regulation of SHBG 5 0.39 3.54 0.52
60 INT159678 Transcription of Tspo 1 0.53 0.64 0.49
61 INT205265 Regulation of Transcription of TSPO 1 0.21 0.13 0.49
62 INT7067 Negative_regulation of Gene_expression of SHBG 7 0.41 5.08 0.48
63 INT206880 Gene_expression of ALDH1A1 5 0.45 5.02 0.45
64 INT61831 Regulation of Regulation of TSPO 1 0.03 0.16 0.43
65 INT104312 Positive_regulation of Transcription of AR 2 0.37 0.96 0.38
66 INT135139 Regulation of Positive_regulation of Tspo 1 0.05 0.17 0.37
67 INT217686 Positive_regulation of Negative_regulation of SHBG 1 0.26 1.97 0.33
68 INT146646 Protein_catabolism of TSPO 3 0.86 0.58 0.32
69 INT17492 Negative_regulation of Binding of Ar 3 0.59 0.76 0.28
70 INT293387 Regulation of Localization of AR 1 0.05 0 0.28
71 INT266974 Protein_catabolism of AR 2 0.34 1.91 0.27
72 INT159677 Positive_regulation of Transcription of Tspo 1 0.46 0.33 0.27
73 INT123520 Gene_expression of Ar 12 0.32 6.98 0.25
74 INT279628 Negative_regulation of Ar 5 0.04 6.1 0.25
75 INT185930 Regulation of Positive_regulation of AR 3 0.20 1.01 0.25
76 INT152667 Negative_regulation of Transcription of AR 3 0.42 0.72 0.24
77 INT112378 Negative_regulation of Regulation of Ar 1 0.43 0.19 0.23
78 INT257784 Positive_regulation of Phosphorylation of AR 2 0.45 0.96 0.21
79 INT213275 Positive_regulation of Gene_expression of SHBG 6 0.46 4.24 0.19
80 INT40059 Regulation of Positive_regulation of SHBG 1 0.45 1.19 0.19
81 INT148210 Positive_regulation of Positive_regulation of SHBG 3 0.45 1.89 0.18
82 INT49346 Transcription of Ar 3 0.63 0.8 0.14
83 INT123527 Negative_regulation of Gene_expression of Ar 2 0.10 0 0.14
84 INT152669 Negative_regulation of Localization of AR 2 0.25 0.75 0.13
85 INT185673 Negative_regulation of Negative_regulation of AR 3 0.28 1.12 0.12
86 INT243079 Regulation of Ar 3 0.08 1.22 0.12
87 INT162432 Positive_regulation of Ar 3 0.23 2.34 0.11
88 INT73848 Positive_regulation of Transcription of TSPO 3 0.42 0.58 0.1
89 INT162428 Localization of Ar 4 0.37 2.4 0.07
90 INT162430 Negative_regulation of Positive_regulation of Ar 1 0.21 1.52 0.07
91 INT243082 Binding of Ar 2 0.11 1.81 0.06
92 INT185666 Positive_regulation of Binding of AR 2 0.33 0.19 0.04
93 INT213380 Regulation of Negative_regulation of AR 1 0.35 0.72 0.04
94 INT213363 Regulation of Gene_expression of Ar 2 0.11 1.63 0.03
95 INT206879 Positive_regulation of Gene_expression of ALDH1A1 1 0.25 1.32 0.03
96 INT206871 Regulation of Gene_expression of ALDH1A1 1 0.23 1.32 0.03
97 INT206873 Negative_regulation of Gene_expression of ALDH1A1 1 0.34 1.3 0.03
98 INT123526 Positive_regulation of Gene_expression of Ar 2 0.11 1.29 0
99 INT209673 Negative_regulation of Binding of AR 2 0.27 0.5 0
100 INT182748 Positive_regulation of Transcription of Ar 1 0.46 0.43 0
101 INT287660 Negative_regulation of Negative_regulation of Ar 1 0.03 0.07 0
102 INT185672 Positive_regulation of Negative_regulation of AR 1 0.27 0 0
103 INT335677 Regulation of Localization of Ar 1 0.00 0 0
104 INT146803 Negative_regulation of Gene_expression of Ar 1 0.16 0.08 0
105 INT293401 Regulation of Gene_expression of Ar 1 0.06 0.07 0
106 INT152665 Negative_regulation of Regulation of AR 1 0.25 0.38 0
107 INT181317 Regulation of Gene_expression of SHBG 1 0.37 0.22 0
108 INT180906 Negative_regulation of Positive_regulation of TSPO 1 0.50 0 0
109 INT152664 Regulation of Transcription of AR 1 0.16 0.25 0
110 INT293772 Negative_regulation of Positive_regulation of AR 1 0.19 0 0
111 INT123516 Phosphorylation of Ar 1 0.19 0.07 0
112 INT274728 Regulation of Binding of TSPO 1 0.02 0 0
113 INT293972 Positive_regulation of Binding of TSPO 1 0.04 1.01 0
114 INT251113 Positive_regulation of Binding of SHBG 1 0.37 0.47 0
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