GO:0005513

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Name detection of calcium ion
Categary Process
Go Slim No
Go Link GO:0005513
Unique Molecular Interactions 49
Total Molecular Interactions 57
Total Single Events 258
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for detection of calcium ion. They are ordered first by their pain relevance and then by number of times they were reported for detection of calcium ion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT175553 Binding of CASR and CP 1 0.11 1.65 1.03
2 INT125568 Binding of Casr and Ncoa6 3 0.50 1.13 0.46
3 INT175552 Binding of CASR and UPF1 1 0.01 0.89 0.33
4 INT125567 Ncoa6 Positive_regulation of Casr 1 0.52 0.46 0.3
5 INT154834 Stim1 Regulation of Regulation of Ca2 1 0.13 0.9 0.28
6 INT125569 In(4)1Dn-p Negative_regulation of Positive_regulation of Casr 1 0.01 0.39 0.25
7 INT262229 Binding of CYP3A4 and Casr 1 0.03 0.37 0.24
8 INT160399 Tns3 Regulation of Casr 1 0.30 0.1 0.22
9 INT160402 Tns3 Regulation of Positive_regulation of Casr 1 0.30 0.1 0.22
10 INT237824 Stim1 Positive_regulation of soc 1 0.26 1.25 0.21
11 INT121382 Casr Positive_regulation of Abcc3 1 0.32 0.25 0.19
12 INT121381 Casr Positive_regulation of Positive_regulation of Abcc3 1 0.30 0.25 0.19
13 INT121380 Casr Positive_regulation of Positive_regulation of Cyp3a11 1 0.15 0.25 0.18
14 INT342152 Binding of Casr and Positive_regulation of Localization of Sst 1 0.07 0.29 0.17
15 INT225607 Ncoa6 Regulation of Gene_expression of Casr 1 0.15 0.68 0.17
16 INT225501 Plcl1 Regulation of Gene_expression of Casr 1 0.04 0.67 0.16
17 INT281194 Casr Positive_regulation of Positive_regulation of Nr1i2 1 0.27 0 0.13
18 INT281193 Nr1i2 Positive_regulation of Positive_regulation of Casr 1 0.27 0 0.13
19 INT136883 Pebp1 Regulation of Localization of Casr 1 0.51 0 0.12
20 INT136876 Ncoa6 Regulation of Localization of Casr 1 0.62 0 0.12
21 INT281192 Casr Positive_regulation of Insig1 1 0.23 0 0.12
22 INT237825 Binding of soc and Stim1 1 0.21 0.29 0.08
23 INT237822 Binding of Stim1 and Trpc1 1 0.54 0.27 0.08
24 INT237808 Binding of Stim1 and Trpv1 1 0.01 0.3 0.08
25 INT310301 Casr Regulation of Tlr4 1 0.04 0.48 0.08
26 INT262176 Nr1i2 Regulation of Regulation of Casr 1 0.11 0.17 0.07
27 INT278611 Binding of CASR and SULT2A1 1 0.03 0 0.07
28 INT262168 Nr1i2 Regulation of Casr 1 0.07 0.17 0.07
29 INT237811 Binding of Esr1 and Stim1 1 0.09 0 0.07
30 INT237821 Binding of Tmie and Stim1 1 0.08 0 0.07
31 INT225494 Binding of Casr and Asc2 1 0.03 0.63 0.07
32 INT237823 Binding of Atp2a2 and Stim1 1 0.06 0 0.07
33 INT237815 Binding of Itpr3 and Stim1 1 0.04 0 0.07
34 INT278685 Binding of CASR and Rxra 1 0.00 0 0.07
35 INT278606 CASR Regulation of SULT2A1 1 0.04 0 0.05
36 INT262217 Casr Regulation of Cyp3a11 1 0.05 0.13 0.03
37 INT192046 Negative_regulation of Binding of RYR2 and Cbx5 1 0.01 1.12 0
38 INT273289 Binding of Psen2 and Ryr2 1 0.27 4.53 0
39 INT192049 Negative_regulation of Binding of RYR2 and Cbx1 1 0.01 1.12 0
40 INT192045 Jup Positive_regulation of RYR2 1 0.11 0.29 0
41 INT160400 Binding of Tns3 and Positive_regulation of Casr 1 0.38 0 0
42 INT249164 Negative_regulation of CA2 Positive_regulation of Gene_expression of STIM1 1 0.14 0 0
43 INT192047 Binding of RYR2 and Cbx1 1 0.01 1.12 0
44 INT192043 Binding of RYR2 and Cbx5 1 0.01 1.12 0
45 INT160401 Tns3 Positive_regulation of Casr 1 0.38 0 0
46 INT192048 Binding of DSP and Ryr2 1 0.24 1.1 0
47 INT262174 Binding of Casr and Foxo1 1 0.05 0.09 0
48 INT192042 Binding of Jup and Ryr2 1 0.17 1.09 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for detection of calcium ion. They are ordered first by their pain relevance and then by number of times they were reported in detection of calcium ion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT175555 Gene_expression of CASR 17 0.78 14.83 3.73
2 INT38013 Gene_expression of Casr 30 0.73 6.03 3.09
3 INT74506 Localization of Casr 16 0.76 1.95 3.06
4 INT121379 Positive_regulation of Casr 13 0.66 2.92 2.34
5 INT105760 Negative_regulation of Casr 5 0.58 0.93 2.17
6 INT38014 Regulation of Casr 7 0.31 1.14 1.87
7 INT129737 Positive_regulation of Casr 2 0.52 2.39 1.33
8 INT154833 Regulation of Stim1 3 0.27 1.56 0.88
9 INT106127 Negative_regulation of CASR 7 0.43 7.12 0.67
10 INT67093 Binding of CASR 3 0.41 3.32 0.64
11 INT175558 Positive_regulation of CASR 5 0.47 3.55 0.6
12 INT154830 Binding of Stim1 1 0.48 1.48 0.56
13 INT342147 Positive_regulation of Positive_regulation of Casr 1 0.52 0.52 0.52
14 INT136865 Positive_regulation of Localization of Casr 1 0.47 0.24 0.51
15 INT281191 Positive_regulation of Gene_expression of Casr 1 0.47 0.18 0.49
16 INT192006 Gene_expression of RYR2 5 0.23 7.69 0.44
17 INT283496 Localization of CASR 2 0.76 2.04 0.41
18 INT215830 Gene_expression of Stim1 3 0.32 0 0.4
19 INT260470 Gene_expression of Casr 3 0.45 0.11 0.37
20 INT342143 Positive_regulation of Localization of Casr 1 0.38 0.58 0.33
21 INT125564 Binding of Casr 2 0.35 0.49 0.31
22 INT309066 Regulation of Gene_expression of Stim1 1 0.14 0 0.3
23 INT237801 Gene_expression of Stim1 1 0.78 1.94 0.29
24 INT125561 Negative_regulation of Gene_expression of Casr 1 0.55 0.48 0.27
25 INT237807 Negative_regulation of Stim1 1 0.43 2.55 0.26
26 INT342149 Binding of Casr 1 0.36 0.47 0.24
27 INT120216 Regulation of RYR2 2 0.28 1.03 0.22
28 INT214967 Negative_regulation of Negative_regulation of Casr 1 0.01 0.19 0.21
29 INT258920 Regulation of CASR 3 0.22 2.02 0.18
30 INT136872 Positive_regulation of Positive_regulation of Casr 1 0.47 0.08 0.18
31 INT341899 Regulation of Stim1 1 0.01 0 0.17
32 INT342144 Localization of Casr 1 0.56 0.29 0.16
33 INT237794 Positive_regulation of Stim1 1 0.70 1.27 0.16
34 INT225385 Transcription of Casr 1 0.15 0.67 0.16
35 INT237795 Positive_regulation of Gene_expression of Stim1 1 0.70 0.94 0.15
36 INT322288 Positive_regulation of Regulation of CASR 1 0.38 0.95 0.14
37 INT281184 Regulation of Positive_regulation of Casr 1 0.31 0 0.13
38 INT165787 Positive_regulation of RYR2 2 0.23 1.3 0.11
39 INT237793 Binding of Stim1 1 0.36 0.26 0.08
40 INT129736 Negative_regulation of Casr 1 0.14 1.28 0.08
41 INT175557 Negative_regulation of Gene_expression of CASR 2 0.55 1.73 0.07
42 INT237796 Localization of Stim1 1 0.75 0 0.07
43 INT123634 Positive_regulation of Negative_regulation of CASR 1 0.15 0.79 0.07
44 INT192016 Localization of RYR2 5 0.25 4.18 0.05
45 INT192012 Binding of RYR2 2 0.30 3.61 0.05
46 INT221865 Positive_regulation of Localization of RYR2 2 0.15 4.56 0.05
47 INT192023 Negative_regulation of RYR2 1 0.15 1.86 0.04
48 INT322462 Transcription of Ryr2 1 0.55 0.47 0.03
49 INT219581 Binding of Ryr2 2 0.27 4.54 0
50 INT219567 Phosphorylation of Ryr2 2 0.62 0.22 0
51 INT219566 Localization of Ryr2 1 0.45 0.49 0
52 INT281185 Regulation of Gene_expression of Casr 1 0.36 0.05 0
53 INT349546 Negative_regulation of Binding of CASR 1 0.07 1.11 0
54 INT322461 Negative_regulation of Transcription of Ryr2 1 0.45 0 0
55 INT219582 Positive_regulation of Phosphorylation of Ryr2 1 0.30 0.22 0
56 INT249283 Positive_regulation of Gene_expression of STIM1 1 0.35 0 0
57 INT192020 Regulation of Localization of RYR2 1 0.15 0.27 0
58 INT249294 Gene_expression of STIM1 1 0.39 0 0
59 INT297204 Regulation of Ryr2 1 0.08 0.3 0
60 INT249244 Binding of STIM1 1 0.24 0 0
61 INT342145 Regulation of Casr 1 0.20 0.08 0
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