GO:0005516

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Name calmodulin binding
Categary Function
Go Slim No
Go Link GO:0005516
Unique Molecular Interactions 1646
Total Molecular Interactions 2265
Total Single Events 25412
Pain Genes Associated 134

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for calmodulin binding. They are ordered first by their pain relevance and then by number of times they were reported for calmodulin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36
2 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25
3 INT251170 Clu Positive_regulation of Trpv1 1 0.28 2.61 6.49
4 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 0.74 4.31 6.1
5 INT351352 Binding of Trpv1 and Lpar1 1 0.21 5.86 4.62
6 INT180774 Gdnf Positive_regulation of Trpv1 1 0.33 2.43 4.37
7 INT136514 Binding of Grm1 and Grm5 4 0.12 1.8 3.9
8 INT317517 Binding of Nos1 and Oprm1 1 0.17 0.22 3.85
9 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79
10 INT136525 Binding of Prokr1 and Trpv1 1 0.39 2.9 3.76
11 INT141254 Ngf Regulation of Transcription of Trpv1 1 0.53 1.37 3.74
12 INT158770 Binding of Trpv1 and Trpa1 5 0.34 2.07 3.5
13 INT195931 Binding of OPRM1 and Trpv1 1 0.07 0.87 3.43
14 INT108472 Binding of NOS1 and PNOC 1 0.32 0.64 3.27
15 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
16 INT251146 Binding of Grin1 and Dlg2 1 0.36 1.95 3.16
17 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
18 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11
19 INT158752 Binding of TRPV1 and Rvm 1 0.05 1.6 3.1
20 INT101408 Binding of Grin1 and Olr1469 1 0.03 0.86 3.1
21 INT101407 Binding of Grin1 and Spr 1 0.14 0.86 3.09
22 INT158751 Binding of TRPV1 and Pag1 1 0.03 1.59 3.08
23 INT122776 Gdnf Positive_regulation of Gene_expression of Trpv1 2 0.67 2.13 3.06
24 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
25 INT156381 Binding of Grin1 and Dlg4 1 0.39 0.86 2.9
26 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79
27 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73
28 INT220061 Binding of TRPV1 and TRPA1 1 0.15 1.7 2.69
29 INT182564 Binding of Ptger2 and Trpv1 1 0.18 1.77 2.67
30 INT351444 Grin1 Positive_regulation of Gria2 1 0.22 1.5 2.64
31 INT251150 Binding of Nos1 and Dlg2 1 0.30 1.98 2.62
32 INT210696 Trpv1 Regulation of Slc12a2 1 0.25 1.97 2.58
33 INT107322 Positive_regulation of TRPV1 Positive_regulation of Localization of IL8 3 0.13 1.64 2.5
34 INT317528 Ppp1r9b Regulation of Grin1 1 0.18 0.2 2.48
35 INT147659 Prkce Positive_regulation of TRPV1 1 0.04 1.42 2.43
36 INT122775 Gdnf Regulation of Gene_expression of Trpv1 4 0.59 2.72 2.42
37 INT103332 Ngf Regulation of Gene_expression of TRPV1 3 0.09 2.6 2.4
38 INT96465 Pnoc Positive_regulation of GEM 1 0.01 0.74 2.39
39 INT74840 Binding of Cacna1a and Cacna1a 5 0.00 4.24 2.36
40 INT107165 Binding of Gabrg1 and Trpv1 2 0.01 0.16 2.34
41 INT152900 TRPV1 Regulation of Gene_expression of CALCA 1 0.69 0.73 2.29
42 INT152901 TRPV1 Regulation of Localization of CALCA 1 0.44 0.73 2.29
43 INT103548 Binding of TRPV1 and TRPV3 3 0.37 1.82 2.28
44 INT228454 Ngf Positive_regulation of Phosphorylation of Trpv1 1 0.39 2.97 2.26
45 INT251164 Binding of Clu and Trpv1 1 0.19 0.44 2.23
46 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21
47 INT140659 Phax Positive_regulation of Trpv1 3 0.49 0.68 2.18
48 INT212301 NGF Regulation of Gene_expression of TRPV1 1 0.23 2.37 2.13
49 INT122660 Binding of CACNA1A and DNAH8 2 0.28 2.68 2.08
50 INT167530 Phax Regulation of Gene_expression of Trpv1 1 0.16 0.86 2.05
51 INT144115 Positive_regulation of Grm5 Positive_regulation of Prkcg 1 0.41 0 2.01
52 INT124133 Camk2a Regulation of Phosphorylation of Creb1 1 0.46 0 2
53 INT317540 Camk2a Negative_regulation of Oprm1 1 0.19 0 1.98
54 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
55 INT104855 Prkaca Regulation of TRPV1 3 0.06 1.52 1.92
56 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
57 INT262558 Phax Positive_regulation of Trpv1 1 0.01 1.26 1.92
58 INT93293 Ngf Regulation of Trpv1 2 0.28 0.71 1.9
59 INT161079 Mcs18 Negative_regulation of Trpv1 1 0.40 0.82 1.9
60 INT169570 Binding of ROS1 and TRPV1 3 0.33 3.07 1.89
61 INT151965 SORBS1 Positive_regulation of TRPV1 1 0.18 0 1.89
62 INT166945 Ngf Positive_regulation of Trpv1 1 0.01 0.47 1.88
63 INT338691 Binding of Trpv1 and Aff3 1 0.24 1.21 1.88
64 INT355251 Cacna1a Regulation of Gene_expression of Gabrg1 1 0.01 0.06 1.86
65 INT355249 Cacna1a Regulation of Gene_expression of Ltp 1 0.04 0.06 1.86
66 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
67 INT349658 Nos2 Regulation of Gene_expression of Nos1 1 0.63 2.86 1.84
68 INT207630 Binding of Calm3 and Nrgn 1 0.06 1.03 1.82
69 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
70 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 0.30 1.36 1.8
71 INT23392 Gal Regulation of Trpv1 1 0.05 0.33 1.77
72 INT276863 Gpr65 Regulation of Trpv1 1 0.25 1.78 1.75
73 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75
74 INT142899 Chn1 Negative_regulation of Positive_regulation of NOS1 1 0.01 1.07 1.75
75 INT182565 Ptger2 Regulation of Trpv1 1 0.25 1.34 1.73
76 INT185143 Elane Positive_regulation of Pik3r1 1 0.01 0 1.72
77 INT278223 Binding of NOS3 and ACSM3 1 0.41 6.32 1.65
78 INT168612 Negative_regulation of Nos1 Negative_regulation of Positive_regulation of Mmp9 1 0.23 0.45 1.62
79 INT147654 DYT10 Negative_regulation of Positive_regulation of TRPV1 1 0.27 0.93 1.62
80 INT147652 PLCB1 Negative_regulation of Positive_regulation of TRPV1 1 0.27 0.92 1.62
81 INT168607 Negative_regulation of Nos1 Negative_regulation of Mmp9 1 0.23 0.45 1.61
82 INT276670 Binding of Trpv1 and Nkx1-1 1 0.07 0.68 1.6
83 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
84 INT355254 Ltp Regulation of Cacna1a 1 0.04 0 1.58
85 INT118515 Positive_regulation of PRKCA Positive_regulation of Phosphorylation of TRPV1 1 0.27 0.56 1.58
86 INT131575 Grin1 Negative_regulation of Positive_regulation of Ephb1 1 0.28 0.31 1.58
87 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56
88 INT208980 Binding of Ca2 and Trpv1 4 0.32 0.67 1.55
89 INT74843 Binding of Cacna1a and Ea2 3 0.13 3.29 1.55
90 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55
91 INT42000 Trpv1 Positive_regulation of Cck 1 0.04 0 1.49
92 INT41999 Trpv1 Positive_regulation of Vip 1 0.04 0 1.49
93 INT112034 Gabrb3 Positive_regulation of Pik3r1 1 0.08 0.18 1.48
94 INT136844 Binding of Prkca and Nrgn 1 0.33 0 1.47
95 INT136843 Binding of Camk2a and Nrgn 1 0.47 0 1.47
96 INT140329 Grin1 Negative_regulation of Ltp 1 0.04 0.64 1.46
97 INT161871 Mors1 Positive_regulation of GRIN1 1 0.01 0.12 1.46
98 INT161858 OPRM1 Positive_regulation of GRIN1 1 0.50 0.12 1.45
99 INT121226 Ngf Regulation of Gene_expression of Trpv1 2 0.62 0.7 1.44
100 INT180789 Ngf Regulation of Localization of Trpv1 1 0.28 1.22 1.44
101 INT180768 Bdnf Regulation of Localization of Trpv1 1 0.13 1.21 1.43
102 INT180790 Gdnf Regulation of Localization of Trpv1 1 0.15 1.21 1.43
103 INT139768 Binding of TRPV1 and ICK 1 0.41 1.59 1.42
104 INT139767 ICK Regulation of TRPV1 1 0.30 1.59 1.42
105 INT134764 Ghrl Regulation of Gene_expression of NOS3 1 0.02 2.66 1.4
106 INT144123 Binding of P2rx6 and Trpv1 1 0.11 0 1.4
107 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
108 INT116827 Binding of UCHL1 and TRPV1 1 0.41 0.88 1.39
109 INT355250 Ltp Regulation of Positive_regulation of Cacna1a 1 0.04 0 1.39
110 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38
111 INT167529 Ppt1 Negative_regulation of Gene_expression of Trpv1 1 0.26 0.49 1.38
112 INT108727 Binding of ATP1A2 and CACNA1A 2 0.34 1.97 1.37
113 INT182558 Binding of Ptgir and Trpv1 1 0.16 1.12 1.37
114 INT276673 Nkx1-1 Regulation of Trpv1 1 0.05 0.16 1.37
115 INT261483 Binding of Ephb1 and Trpv1 1 0.39 1.37 1.37
116 INT355248 Ltp Positive_regulation of Localization of Trpv1 1 0.51 0 1.35
117 INT122659 Binding of CACNA1A and SAR1B 1 0.06 1.38 1.35
118 INT355253 Ltp Positive_regulation of Cacna1a 1 0.05 0 1.34
119 INT121457 KNG1 Positive_regulation of Trpv1 1 0.16 0.91 1.33
120 INT317519 Grin1 Positive_regulation of Negative_regulation of Oprm1 1 0.14 0 1.31
121 INT355252 Binding of Cacna1a and Cnr1 1 0.04 0 1.31
122 INT181492 NGF Regulation of TRPV1 1 0.21 0.93 1.31
123 INT242605 Gdnf Positive_regulation of Trpv1 1 0.26 0.17 1.3
124 INT169297 TRPV1 Positive_regulation of EGFR 1 0.64 0.37 1.3
125 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29
126 INT208990 Binding of CALM1 and Trpv1 1 0.10 0.07 1.29
127 INT147653 TACR1 Positive_regulation of TRPV1 1 0.02 0.72 1.29
128 INT135830 Gch1 Regulation of Nos2 1 0.65 0 1.29
129 INT168866 Binding of RYR1 and Cd38 1 0.02 0.17 1.28
130 INT154203 Binding of Pick1 and Grm7 1 0.41 1.64 1.28
131 INT125950 Syt17 Regulation of Trpv1 1 0.11 0.43 1.28
132 INT74841 Binding of Cacna1a and Ea2 2 0.01 2.33 1.27
133 INT64077 Trpv1 Positive_regulation of Kcnma1 1 0.00 0.37 1.27
134 INT342990 TRPV1 Positive_regulation of Gene_expression of SFTPA1 1 0.06 1.44 1.26
135 INT116892 Binding of TRPV1 and Phax 4 0.00 0.1 1.24
136 INT132465 Ltf Positive_regulation of Nos1 1 0.35 0.05 1.24
137 INT314198 Mapk14 Positive_regulation of Gene_expression of Trpv1 1 0.48 1.09 1.24
138 INT195926 Prkaca Positive_regulation of Trpv1 1 0.10 0.44 1.24
139 INT199593 Binding of TRPV1 and Myoz1 1 0.10 1.7 1.23
140 INT342988 HCL1 Positive_regulation of TRPV1 1 0.04 1.15 1.21
141 INT142154 Trpv1 Positive_regulation of Gene_expression of Il2 1 0.22 0 1.21
142 INT166301 Adrbk1 Positive_regulation of Localization of Trpv1 1 0.45 1.17 1.2
143 INT93294 Ngf Regulation of Transcription of Trpv1 1 0.01 0.36 1.19
144 INT65203 OPRL1 Negative_regulation of ADCY1 1 0.19 0 1.19
145 INT49955 OPRM1 Positive_regulation of ADCY1 1 0.21 0.31 1.19
146 INT93290 Ngf Regulation of Transcription of Trpv1 1 0.02 0.34 1.16
147 INT93289 Ngf Regulation of Trpv1 1 0.05 0.34 1.16
148 INT121725 Binding of Trpv1 and Pik3cb 1 0.35 0.62 1.15
149 INT308172 Rvm Positive_regulation of Phosphorylation of GRIN1 1 0.50 0.68 1.14
150 INT65204 PNOC Negative_regulation of ADCY1 1 0.07 0 1.14
151 INT317553 Binding of Car2 and Grin1 1 0.07 0 1.14
152 INT123387 Binding of Camk2a and Gria2 1 0.13 0.32 1.14
153 INT317549 Negative_regulation of Camk2a Negative_regulation of Phosphorylation of Oprm1 1 0.19 0 1.14
154 INT69504 Binding of Nos1 and Gatm 1 0.05 0 1.13
155 INT110669 Binding of Alox5 and Trpv1 1 0.07 0.2 1.13
156 INT163799 Binding of GRIN1 and Rvm 1 0.16 0.96 1.13
157 INT121362 Trpv1 Regulation of Localization of Ins1 1 0.51 0.17 1.12
158 INT332776 FSCN1 Positive_regulation of Grin1 1 0.02 0.21 1.12
159 INT182550 Ptger1 Negative_regulation of Trpv1 1 0.35 0.73 1.12
160 INT147660 Positive_regulation of Prkce Positive_regulation of TRPV1 1 0.04 0.69 1.12
161 INT142572 D5Pas1 Negative_regulation of Nos1 2 0.02 0.14 1.11
162 INT65254 LOC100360318 Regulation of Gene_expression of Basp1 1 0.00 0.05 1.11
163 INT317527 Binding of Hint1 and Nos1 1 0.27 0.1 1.11
164 INT122268 Binding of Grin2b and Grm5 1 0.40 0.52 1.1
165 INT269191 Binding of Grin1 and Grin3a 2 0.32 1.05 1.09
166 INT121730 Pik3cb Regulation of Trpv1 1 0.58 0.54 1.09
167 INT305734 Binding of Sort1 and Trpv1 1 0.01 0.5 1.08
168 INT105690 Ngf Positive_regulation of TRPV1 1 0.05 1.43 1.08
169 INT317561 Binding of Grin1 and Oprm1 1 0.14 0.09 1.08
170 INT83936 Binding of Mtap2 and Penk 1 0.22 0.19 1.07
171 INT181493 TRPV4 Regulation of Gene_expression of NGF 1 0.24 0.7 1.07
172 INT317531 Regulation of Binding of Grin1 and Mors1 1 0.08 0.06 1.05
173 INT146496 Snta1 Positive_regulation of Gene_expression of Adrbk1 1 0.13 0.73 1.05
174 INT317534 Regulation of Binding of Camk2a and Grin1 1 0.20 0.06 1.05
175 INT269199 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.03 0.56 1.05
176 INT154846 Negative_regulation of Mapk14 Negative_regulation of Positive_regulation of Trpv1 1 0.23 0.07 1.05
177 INT317535 Binding of Grin1 and Mors1 1 0.07 0.06 1.04
178 INT130167 Trpv1 Regulation of Localization of Calca 2 0.38 0.69 1.03
179 INT162250 Binding of TRPV1 and Grm5 1 0.01 0.8 1.03
180 INT144069 Positive_regulation of TRPV1 Positive_regulation of Gene_expression of MMP1 1 0.43 1.35 1.03
181 INT114553 Binding of Trpv1 and Col4a4 1 0.01 0.44 1.03
182 INT132464 Ltf Negative_regulation of Positive_regulation of Nos1 1 0.33 0 1.03
183 INT114554 Binding of St3gal3 and Trpv1 1 0.01 0.44 1.03
184 INT263232 Prkcg Positive_regulation of Trpv4 1 0.12 1.1 1.02
185 INT157142 OPA1 Positive_regulation of Gene_expression of Camk2a 1 0.02 0.3 1.02
186 INT269194 Ceacam3 Positive_regulation of Phosphorylation of Grin1 1 0.09 0.55 1.02
187 INT148327 Binding of Pkd1 and Trpv1 1 0.52 2.23 1.01
188 INT131889 gr Regulation of Gene_expression of Grin1 1 0.02 0 1.01
189 INT119914 Olr1714 Negative_regulation of Nos1 1 0.02 0.47 1.01
190 INT186161 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.11 1.05 1.01
191 INT317532 Grin1 Regulation of Negative_regulation of Oprm1 1 0.18 0.07 1
192 INT317555 Nos1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
193 INT263227 Positive_regulation of Prkcg Regulation of Trpv4 1 0.07 0.95 1
194 INT317544 Camk2a Regulation of Negative_regulation of Oprm1 1 0.20 0.07 1
195 INT317564 Pik3r1 Regulation of Negative_regulation of Oprm1 1 0.13 0.07 1
196 INT53052 ANTXRL Negative_regulation of Negative_regulation of ADCY1 1 0.01 0.66 0.99
197 INT283932 Positive_regulation of Mapk14 Regulation of Gene_expression of Trpv1 1 0.14 1.28 0.99
198 INT156510 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.03 0.98 0.98
199 INT156508 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.22 0.98 0.98
200 INT353372 Dio1 Positive_regulation of Grin1 1 0.16 0 0.98

Single Events

The table below shows the top 100 pain related interactions that have been reported for calmodulin binding. They are ordered first by their pain relevance and then by number of times they were reported in calmodulin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59
2 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42
3 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42
4 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81
5 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05
6 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59
7 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07
8 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61
9 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24
10 INT60126 Regulation of Trpv1 186 0.62 85.53 133.4
11 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75
12 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38
13 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85
14 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71
15 INT49171 Gene_expression of Nos1 241 0.78 140.7 104.76
16 INT89054 Positive_regulation of Gene_expression of Trpv1 156 0.70 90.78 102.03
17 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71
18 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43
19 INT38731 Localization of Trpv1 138 0.81 52.73 90.49
20 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32
21 INT4830 Binding of Trpv1 158 0.48 45.11 84.2
22 INT12476 Negative_regulation of TRPV1 124 0.59 47.95 77.98
23 INT9382 Regulation of TRPV1 149 0.62 53.99 77.46
24 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7
25 INT98621 Regulation of Trpv1 121 0.62 79.24 75.23
26 INT14049 Positive_regulation of GRIN1 102 0.70 48.31 71.06
27 INT6490 Negative_regulation of ADCY1 145 0.58 26.25 70.96
28 INT87686 Positive_regulation of Gene_expression of Trpv1 101 0.70 72.41 69.15
29 INT1599 Positive_regulation of ADCY1 146 0.67 30.05 64.9
30 INT96622 Localization of Trpv1 110 0.81 59.82 63.25
31 INT79093 Positive_regulation of Nos1 101 0.70 46.89 59.61
32 INT90911 Positive_regulation of Phosphorylation of Grin1 62 0.70 27.45 59.26
33 INT49170 Negative_regulation of Nos1 116 0.59 60.66 58.87
34 INT7340 Regulation of Grin1 87 0.62 30.37 57.93
35 INT83602 Positive_regulation of Gene_expression of TRPV1 114 0.70 51.19 56.35
36 INT49436 Binding of TRPV1 145 0.48 38.35 55.08
37 INT119528 Positive_regulation of Camk2a 135 0.70 26.13 54.7
38 INT4957 Negative_regulation of Grin1 87 0.59 24.51 53.21
39 INT64110 Positive_regulation of Gene_expression of Nos1 68 0.70 58.11 51.64
40 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57
41 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05
42 INT57021 Positive_regulation of Gene_expression of Grin1 62 0.70 24.77 47.31
43 INT66331 Gene_expression of Cacna1a 101 0.78 49.58 46.32
44 INT9383 Localization of TRPV1 98 0.81 33.23 46.24
45 INT98498 Binding of Trpv1 75 0.48 33.67 44.4
46 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65
47 INT65245 Gene_expression of Nos3 121 0.78 98.14 41.56
48 INT92517 Gene_expression of Grin1 105 0.78 29.53 39.43
49 INT26698 Positive_regulation of Cacna1a 37 0.67 26.33 39.1
50 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94
51 INT58062 Negative_regulation of Gene_expression of Trpv1 66 0.59 22.34 38.02
52 INT115649 Gene_expression of Camk2a 95 0.78 33.22 38
53 INT11246 Binding of Grin1 65 0.48 14.53 36.93
54 INT80075 Regulation of Gene_expression of Trpv1 55 0.62 32.42 36.88
55 INT64558 Negative_regulation of Nos1 88 0.58 26.76 36.78
56 INT79060 Gene_expression of NOS2 116 0.78 69.25 34.84
57 INT76531 Transcription of Trpv1 62 0.72 23.69 34.77
58 INT52194 Positive_regulation of Grin1 83 0.69 25.09 34.76
59 INT96624 Positive_regulation of Positive_regulation of Trpv1 62 0.70 20.5 34.28
60 INT47710 Negative_regulation of GRIN1 71 0.57 25.57 34.24
61 INT114729 Phosphorylation of Camk2a 110 0.82 15.49 33.19
62 INT109820 Gene_expression of Trpv4 121 0.78 39.69 33.11
63 INT57024 Regulation of Gene_expression of Grin1 32 0.62 9.77 32.6
64 INT92837 Negative_regulation of Gene_expression of Nos2 116 0.59 59.67 31.82
65 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72
66 INT67912 Gene_expression of GRIN1 75 0.77 28.99 29.28
67 INT106540 Negative_regulation of Phosphorylation of Grin1 15 0.58 9.32 29.13
68 INT80470 Negative_regulation of Gene_expression of Grin1 33 0.59 10.22 27.15
69 INT51602 Gene_expression of Grm5 59 0.75 17.29 26.99
70 INT95481 Regulation of Gene_expression of TRPV1 48 0.62 29.3 26.28
71 INT112036 Phosphorylation of Trpv1 51 0.82 18.59 25.6
72 INT61664 Regulation of GRIN1 38 0.60 16.45 25.35
73 INT74688 Regulation of Nos1 55 0.62 22.16 25.3
74 INT103320 Positive_regulation of Positive_regulation of Trpv1 44 0.70 27.73 25.28
75 INT41487 Negative_regulation of Cacna1a 16 0.57 9.42 25.2
76 INT92105 Transcription of Trpv1 47 0.71 27.47 25.01
77 INT48766 Regulation of NOS1 73 0.61 37.01 24.59
78 INT9377 Positive_regulation of Positive_regulation of TRPV1 43 0.70 15.81 24.47
79 INT10240 Gene_expression of Gap43 58 0.78 22.11 24.45
80 INT89854 Regulation of Nos2 49 0.61 42.58 24.1
81 INT79061 Positive_regulation of NOS2 92 0.65 58.89 23.96
82 INT123386 Negative_regulation of Camk2a 48 0.58 12.57 23.78
83 INT49172 Regulation of Nos1 43 0.52 27.53 23.66
84 INT125190 Regulation of Gene_expression of Trpv1 38 0.62 32.57 23.2
85 INT106720 Positive_regulation of Adcy1 30 0.50 22.05 22.68
86 INT78571 Positive_regulation of Grm5 35 0.69 11.81 22.45
87 INT89056 Phosphorylation of Trpv1 46 0.82 13.52 22.16
88 INT70504 Regulation of Gene_expression of NOS1 30 0.51 21.72 21.72
89 INT121872 Gene_expression of Camk4 156 0.78 70.47 21.39
90 INT74059 Positive_regulation of Gene_expression of Nos1 55 0.70 11.5 21.39
91 INT112029 Positive_regulation of Pik3r1 90 0.67 38.76 20.95
92 INT66281 Transcription of Nos2 81 0.71 39.49 20.37
93 INT112174 Gene_expression of Trpv4 47 0.78 26.26 20.09
94 INT96511 Negative_regulation of Positive_regulation of Trpv1 35 0.59 10.95 19.79
95 INT77902 Negative_regulation of Positive_regulation of TRPV1 30 0.59 9.36 19.2
96 INT50420 Transcription of Grin1 30 0.71 13.21 18.28
97 INT90937 Negative_regulation of Gene_expression of Trpv1 34 0.59 22.74 18.12
98 INT83198 Positive_regulation of Nos3 78 0.64 35.69 17.71
99 INT63928 Negative_regulation of Grin1 51 0.56 11.81 17.57
100 INT31136 Binding of Cacna1a 28 0.45 30.76 17.35
101 INT119233 Positive_regulation of Trpv4 65 0.70 20.21 17.3
102 INT101501 Phosphorylation of TRPV1 31 0.82 9.26 17.27
103 INT16624 Localization of Grin1 38 0.79 8.46 17.15
104 INT88356 Negative_regulation of Positive_regulation of Grin1 16 0.58 4.72 16.58
105 INT77433 Regulation of Gene_expression of Nos2 49 0.62 35.07 16.33
106 INT112027 Gene_expression of Pik3r1 58 0.75 30.9 15.95
107 INT12617 Regulation of ADCY1 41 0.61 7.38 15.94
108 INT115650 Positive_regulation of Gene_expression of Camk2a 37 0.70 17.68 15.73
109 INT114025 Transcription of Nos1 20 0.70 16.48 15.63
110 INT18513 Binding of GRIN1 32 0.47 9.44 15.08
111 INT74098 Negative_regulation of Gene_expression of Nos1 36 0.59 16.25 14.82
112 INT64112 Regulation of Gene_expression of Nos1 22 0.62 21.45 14.76
113 INT92513 Regulation of Grin1 26 0.59 9.12 13.94
114 INT103828 Negative_regulation of Gene_expression of TRPV1 23 0.59 13.63 13.81
115 INT7342 Positive_regulation of Positive_regulation of Grin1 18 0.50 9.22 13.76
116 INT130424 Negative_regulation of Adcy1 19 0.58 16.31 13.6
117 INT97848 Positive_regulation of Localization of Trpv1 18 0.50 7.66 13.36
118 INT83200 Positive_regulation of Gene_expression of Nos3 48 0.70 24.75 12.99
119 INT101494 Regulation of Positive_regulation of Trpv1 18 0.62 6.57 12.9
120 INT114420 Negative_regulation of Pik3r1 67 0.54 34.86 12.82
121 INT119089 Regulation of Phosphorylation of Grin1 17 0.61 3.1 12.82
122 INT121242 Positive_regulation of Gene_expression of Nos3 37 0.69 31.96 12.71
123 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48
124 INT90909 Negative_regulation of Gene_expression of NOS1 44 0.55 23.83 12.47
125 INT30101 Regulation of Cacna1a 25 0.45 14.38 12.43
126 INT136537 Phosphorylation of Nrgn 8 0.82 1.27 12.41
127 INT97237 Transcription of TRPV1 33 0.72 10.56 12.4
128 INT112103 Binding of Grin1 28 0.48 4.21 12.08
129 INT145515 Positive_regulation of Localization of Trpv1 23 0.50 10.12 12.08
130 INT11429 Gene_expression of ADCY1 26 0.74 5.89 11.93
131 INT73431 Positive_regulation of Nos3 82 0.65 53.22 11.61
132 INT97381 Negative_regulation of Positive_regulation of Nos2 34 0.59 16.66 11.6
133 INT107522 Regulation of Grm5 9 0.44 6.42 11.46
134 INT116347 Positive_regulation of Positive_regulation of GRIN1 12 0.49 3.63 11.44
135 INT95369 Positive_regulation of Gene_expression of NOS2 36 0.55 25.09 11.37
136 INT86544 Positive_regulation of Camk2a 20 0.47 4.59 11.37
137 INT47702 Gene_expression of Sptan1 24 0.76 7.6 11.36
138 INT40486 Positive_regulation of Positive_regulation of ADCY1 20 0.48 4.29 11.33
139 INT80251 Binding of Nos1 21 0.30 8.24 11.31
140 INT204112 Gene_expression of GEM 43 0.75 38.74 11.23
141 INT48912 Localization of NOS1 52 0.77 24.14 10.92
142 INT75765 Positive_regulation of Gene_expression of Cacna1a 17 0.70 17.51 10.91
143 INT118676 Positive_regulation of Camk4 34 0.70 16.67 10.9
144 INT118678 Phosphorylation of Camk4 22 0.82 9.4 10.7
145 INT112037 Negative_regulation of Positive_regulation of Trpv1 19 0.59 8.9 10.55
146 INT90114 Regulation of Gene_expression of Nos1 18 0.62 6.38 10.52
147 INT86361 Positive_regulation of Positive_regulation of NOS1 39 0.53 18.93 10.42
148 INT110017 Phosphorylation of Nos1 12 0.60 1.64 10.3
149 INT12620 Negative_regulation of Negative_regulation of ADCY1 16 0.44 2.98 10.1
150 INT75919 Gene_expression of Slc8a1 23 0.63 16.44 9.84
151 INT6065 Localization of GRIN1 15 0.74 3.15 9.81
152 INT95271 Negative_regulation of Nos3 46 0.53 24.1 9.71
153 INT89053 Positive_regulation of Phosphorylation of Trpv1 16 0.70 8.89 9.39
154 INT88559 Negative_regulation of Spink1 25 0.56 21.81 9.28
155 INT78570 Negative_regulation of Grm5 15 0.57 5.45 9.17
156 INT119527 Regulation of Camk2a 26 0.60 5.55 9.01
157 INT119529 Positive_regulation of Phosphorylation of Camk2a 16 0.60 1.49 8.94
158 INT107657 Positive_regulation of Positive_regulation of Grm5 6 0.69 1.83 8.92
159 INT121987 Phosphorylation of Grin1 11 0.80 4.73 8.88
160 INT68267 Gene_expression of CACNA1A 22 0.75 11.39 8.65
161 INT71590 Gene_expression of Camk2a 17 0.78 2.3 8.63
162 INT10241 Positive_regulation of Gap43 26 0.70 9.89 8.54
163 INT119525 Negative_regulation of Positive_regulation of Camk2a 14 0.43 5.15 8.45
164 INT106719 Gene_expression of Adcy1 18 0.77 12.18 8.42
165 INT1682 Negative_regulation of Rem1 28 0.37 7.38 8.4
166 INT48908 Transcription of NOS1 27 0.55 13.46 8.39
167 INT84672 Negative_regulation of Positive_regulation of Nos1 12 0.48 3.76 8.27
168 INT124702 Positive_regulation of Trpv4 21 0.69 7.14 8.2
169 INT116605 Binding of Nos2 28 0.37 16.88 8.18
170 INT54681 Negative_regulation of Positive_regulation of ADCY1 16 0.38 2.7 8.14
171 INT117642 Regulation of Gene_expression of Grin1 18 0.53 7.09 8.08
172 INT114023 Positive_regulation of Transcription of Nos1 7 0.60 5.35 8.06
173 INT71381 Localization of Nos1 33 0.79 11.46 8.05
174 INT73544 Gene_expression of Grm7 34 0.64 31.28 8.04
175 INT76091 Positive_regulation of NOS3 48 0.61 18.4 7.92
176 INT172789 Regulation of Gene_expression of Nos3 15 0.53 16.23 7.86
177 INT112191 Positive_regulation of Transcription of Nos2 22 0.66 12.4 7.74
178 INT85751 Positive_regulation of Positive_regulation of Nos2 40 0.60 23.53 7.72
179 INT135113 Localization of Grin1 18 0.73 3.73 7.69
180 INT65246 Negative_regulation of Nos3 36 0.50 25.65 7.62
181 INT110705 Positive_regulation of Positive_regulation of Grin1 11 0.69 4.7 7.33
182 INT136533 Positive_regulation of Phosphorylation of Nrgn 7 0.70 0.72 7.27
183 INT20423 Positive_regulation of Gene_expression of Gap43 16 0.70 6.63 6.8
184 INT132468 Positive_regulation of Positive_regulation of Camk2a 20 0.70 2.76 6.7
185 INT92741 Positive_regulation of Positive_regulation of Nos1 8 0.47 1.44 6.58
186 INT89131 Negative_regulation of NOS2 20 0.58 9.68 6.56
187 INT91821 Binding of Cacna1a 16 0.48 13.1 6.37
188 INT90777 Gene_expression of Kcnn3 39 0.77 10.35 6.35
189 INT83712 Transcription of Nos3 19 0.69 13.09 6.31
190 INT124881 Binding of Trpv4 35 0.47 7.71 6.24
191 INT69499 Binding of Nos1 15 0.36 2.56 6.23
192 INT103378 Binding of Spink1 24 0.40 15.3 6.19
193 INT153959 Phosphorylation of GRIN1 8 0.80 4.07 6.18
194 INT93658 Transcription of Nos1 16 0.72 6.85 6.16
195 INT64111 Negative_regulation of Gene_expression of Nos1 22 0.57 8.96 6.02
196 INT149385 Positive_regulation of TRPV4 11 0.69 7.22 6.02
197 INT118440 Gene_expression of TRPV4 20 0.71 7.33 6.01
198 INT103319 Regulation of Positive_regulation of Trpv1 11 0.45 8.37 5.99
199 INT141751 Localization of Syt1 21 0.78 11.19 5.98
200 INT48911 Binding of NOS1 24 0.40 11.21 5.89
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