GO:0005518

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Name collagen binding
Categary Function
Go Slim No
Go Link GO:0005518
Unique Molecular Interactions 581
Total Molecular Interactions 814
Total Single Events 7039
Pain Genes Associated 60

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for collagen binding. They are ordered first by their pain relevance and then by number of times they were reported for collagen binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113550 Binding of FN1 and VTN 6 0.30 5.24 1.91
2 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85
3 INT100771 Binding of Itga1 and Vcam1 3 0.11 3.91 1.79
4 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
5 INT326509 Binding of ACE and VWF 1 0.05 2.07 1.59
6 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
7 INT54601 Binding of Mtor and Ache 1 0.20 0.8 1.58
8 INT201950 IFNA1 Positive_regulation of Binding of DPP4 1 0.12 2.17 1.47
9 INT201946 IFNA1 Positive_regulation of DPP4 1 0.17 2.16 1.46
10 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
11 INT131949 ANTXR1 Positive_regulation of NAV1 1 0.03 0.23 1.38
12 INT158762 Binding of Vwf and Mthfr 1 0.05 1.85 1.37
13 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33
14 INT201942 DPP4 Negative_regulation of CXCL10 1 0.33 0.9 1.3
15 INT271602 Binding of Pdgfa and Pdgfrl 1 0.02 0.86 1.25
16 INT202042 CAMK2N2 Negative_regulation of MMP9 1 0.01 0.73 1.25
17 INT187172 RPS3AP9 Negative_regulation of MMP9 1 0.00 0.89 1.2
18 INT150787 ZNF398 Positive_regulation of Gene_expression of SPARC 1 0.13 1.02 1.05
19 INT106706 POMC Negative_regulation of Binding of FN1 1 0.19 0.79 1.02
20 INT187111 TIMP2 Regulation of MMP9 1 0.23 1.47 0.97
21 INT266659 Binding of MMP9 and MOCS1 1 0.01 1.71 0.94
22 INT222979 Negative_regulation of Binding of COL1A1 and FN1 1 0.01 1.64 0.93
23 INT222978 Binding of COL1A1 and FN1 1 0.01 1.64 0.92
24 INT271601 Pdgfa Positive_regulation of Pdgfrl 1 0.03 0.83 0.91
25 INT251704 Ache Regulation of Gene_expression of Acot1 1 0.08 1.68 0.87
26 INT340437 Binding of SERPINH1 and HLA-DRB4 1 0.00 2.26 0.84
27 INT107698 FN1 Positive_regulation of Gene_expression of CPOX 1 0.13 0.26 0.84
28 INT113250 Olr1259 Negative_regulation of Ache 1 0.01 0.38 0.83
29 INT196525 Binding of MMP2 and MMP9 2 0.32 2.49 0.78
30 INT84466 DPP4 Regulation of Localization of Naga 1 0.00 0.87 0.78
31 INT113546 Binding of FN1 and ITGA3 1 0.03 2.12 0.77
32 INT46246 Tpsg1 Regulation of Ache 1 0.15 0.06 0.76
33 INT46247 Tpsg1 Regulation of Binding of Ache 1 0.15 0.06 0.76
34 INT88921 Positive_regulation of CYP2D6 Negative_regulation of ANTXR1 1 0.00 0.8 0.75
35 INT88922 CYP2D6 Negative_regulation of ANTXR1 1 0.00 0.8 0.75
36 INT201947 IFNA1 Positive_regulation of Gene_expression of DPP4 1 0.11 1.09 0.74
37 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74
38 INT4917 Binding of Pcolce and Tac2 1 0.03 0 0.74
39 INT170992 Binding of FN1 and MMRN1 3 0.01 2.13 0.73
40 INT18447 Binding of Ache and Chat 2 0.33 0.33 0.73
41 INT224580 Gene_expression of IL18 Positive_regulation of SERPINH1 1 0.00 1.34 0.7
42 INT295720 PTGER2 Regulation of MMP9 1 0.01 0.53 0.7
43 INT102863 Prkaca Regulation of Srgn 1 0.50 0.05 0.64
44 INT302469 F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.82 0.62
45 INT282286 Akt1 Positive_regulation of Pak1 1 0.15 0.24 0.61
46 INT295724 CXCL12 Positive_regulation of MMP9 1 0.02 0.32 0.6
47 INT295721 CSF2 Positive_regulation of MMP9 1 0.06 0.32 0.6
48 INT202038 MMP9 Positive_regulation of IL8 1 0.05 0.29 0.59
49 INT175626 TIMP1 Positive_regulation of Gene_expression of MMP9 1 0.03 0.72 0.57
50 INT129271 Binding of ANTXR1 and Efs 1 0.00 0 0.56
51 INT265463 CSPG4 Negative_regulation of Gene_expression of IL6 1 0.06 1.6 0.56
52 INT173556 TIMP1 Negative_regulation of MMP9 1 0.02 0 0.56
53 INT175623 TIMP1 Positive_regulation of MMP9 1 0.03 0.71 0.56
54 INT137897 Binding of SERPINH1 and IL36B 1 0.00 0.64 0.55
55 INT91428 CD44 Positive_regulation of Binding of MMRN1 1 0.24 0.85 0.55
56 INT343913 Binding of FOS and Smad3 1 0.19 0.92 0.54
57 INT150800 THBS3 Negative_regulation of SPARC 1 0.23 0.51 0.53
58 INT196524 Binding of MMP1 and MMP9 1 0.31 0.74 0.51
59 INT196519 Positive_regulation of Binding of MMP1 and MMP9 1 0.42 0.74 0.51
60 INT187116 TIMP2 Negative_regulation of MMP9 1 0.36 1.37 0.5
61 INT36143 Binding of SERPINH1 and HLA-B 1 0.00 0.66 0.49
62 INT175326 SERPINH1 Regulation of Pnlip 1 0.00 0.53 0.49
63 INT127664 Negative_regulation of PDE4A Negative_regulation of MMP9 1 0.37 0.76 0.48
64 INT127665 Negative_regulation of PDE4A Negative_regulation of Transcription of MMP9 1 0.37 0.76 0.48
65 INT352892 Binding of CAV1 and ITGA2 1 0.20 1.61 0.47
66 INT147444 PDGFA Positive_regulation of Gene_expression of Ros1 2 0.00 0.95 0.46
67 INT187099 Binding of Cd4 and Itga1 1 0.00 1.09 0.46
68 INT168445 Positive_regulation of C2 Positive_regulation of Positive_regulation of Dcn 1 0.14 0.66 0.46
69 INT117776 Binding of Ptk2 and Regulation of Phosphorylation of Ddr1 1 0.10 0.17 0.46
70 INT299041 SPARC Regulation of Gene_expression of NPEPPS 1 0.01 0.83 0.42
71 INT226070 Binding of CRP and MMP9 1 0.51 1.13 0.42
72 INT107701 Negative_regulation of FN1 Positive_regulation of CPOX 1 0.11 0.13 0.42
73 INT303857 DDR1 Positive_regulation of IL8 1 0.05 1.5 0.42
74 INT303858 DDR1 Positive_regulation of CXCR2 1 0.11 1.5 0.42
75 INT201943 Regulation of Binding of DPP4 and CXCL10 1 0.20 0.58 0.42
76 INT248239 Binding of FN1 and SDC3 1 0.00 0.77 0.42
77 INT299040 Binding of COL7A1 and SPARC 1 0.02 0.7 0.42
78 INT107696 FN1 Positive_regulation of CPOX 1 0.12 0.13 0.41
79 INT248236 Binding of FN1 and SDC1 1 0.00 0.76 0.41
80 INT120894 Binding of Gp1ba and Vwf 1 0.00 1.38 0.4
81 INT346150 Binding of ADM and FN1 1 0.10 0.93 0.39
82 INT265465 CSPG4 Negative_regulation of Gene_expression of IL8 1 0.07 0.98 0.39
83 INT226072 Binding of MMP9 and SHBG 1 0.15 1.02 0.39
84 INT346135 Positive_regulation of Binding of ADM and FN1 1 0.13 0.93 0.39
85 INT201948 Binding of DPP4 and CXCL10 1 0.27 0.54 0.39
86 INT305407 Binding of ST8SIA2 and ANTXR1 1 0.00 0.09 0.38
87 INT291616 Cby1 Positive_regulation of Gene_expression of Smad7 1 0.00 0.79 0.38
88 INT305405 Binding of KCNMA1 and ANTXR1 1 0.00 0.09 0.38
89 INT200469 Binding of COL7A1 and COMP 1 0.04 0.91 0.38
90 INT166792 Binding of CD44 and HRAS 3 0.12 1.49 0.37
91 INT113560 Negative_regulation of Binding of FN1 and PLAUR 1 0.26 0.87 0.37
92 INT113556 Binding of FN1 and PLAUR 1 0.22 0.81 0.37
93 INT151698 Binding of RNF130 and Vwf 1 0.04 0.29 0.37
94 INT113555 Negative_regulation of Binding of FN1 and VTN 1 0.23 0.87 0.37
95 INT172023 Binding of FN1 and PRTN3 1 0.00 1.05 0.37
96 INT133307 Binding of CD44 and SPP1 5 0.26 2.6 0.35
97 INT302466 Positive_regulation of F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.1 0.35
98 INT254393 Binding of FN1 and GSN 1 0.01 1.08 0.34
99 INT323352 Binding of F8 and VWF 5 0.08 2.22 0.33
100 INT51630 Binding of ACHE and OPRM1 1 0.11 0 0.33
101 INT333993 Binding of Vcam1 and Vwf 1 0.00 1.32 0.33
102 INT110350 Positive_regulation of Arigg3 Positive_regulation of Positive_regulation of Dpp4 1 0.01 0 0.33
103 INT322045 Gp6 Positive_regulation of Gene_expression of Selp 1 0.04 0.15 0.33
104 INT295755 Fgf2 Regulation of MMP9 1 0.07 0.99 0.33
105 INT51628 Binding of ACHE and DRD3 1 0.15 0 0.33
106 INT295717 VEGFA Regulation of MMP9 1 0.01 0.98 0.33
107 INT340616 COL4A4 Regulation of MMP9 1 0.12 0.95 0.32
108 INT44127 Agt Negative_regulation of DSPP 1 0.02 0 0.32
109 INT311228 DPP4 Negative_regulation of Localization of GLP1R 1 0.31 1.25 0.32
110 INT257739 SAGE1 Positive_regulation of DDR1 1 0.00 0.91 0.31
111 INT187102 Negative_regulation of Binding of MMP9 and TIMP2 1 0.36 0.69 0.3
112 INT118300 Vwf Positive_regulation of Crp 1 0.00 0.87 0.3
113 INT213062 PTGS1 Regulation of Gene_expression of MMP9 1 0.04 0.25 0.3
114 INT187106 Binding of MMP9 and TIMP2 1 0.30 0.69 0.3
115 INT225021 PDGFB Positive_regulation of Ccl21 1 0.10 0.07 0.3
116 INT333398 CFD Negative_regulation of Gene_expression of Pdgfa 1 0.02 0.64 0.3
117 INT187113 Binding of IGHG3 and MMP9 1 0.01 0.63 0.3
118 INT225026 PDGFB Positive_regulation of Gene_expression of Ccl21 1 0.10 0.07 0.3
119 INT260896 CRH Positive_regulation of Localization of MMP9 1 0.15 0.15 0.3
120 INT179844 Nid1 Regulation of Negative_regulation of Il11 1 0.19 0 0.29
121 INT202313 Gene_expression of PDGFB Positive_regulation of Positive_regulation of Pdgfrb 1 0.14 1 0.29
122 INT187105 TIMP2 Negative_regulation of Positive_regulation of MMP9 1 0.36 0.36 0.29
123 INT57498 Vwf Positive_regulation of F8 1 0.00 0.36 0.29
124 INT202314 Gene_expression of PDGFB Positive_regulation of Phosphorylation of Pdgfrb 1 0.14 1 0.29
125 INT132426 Binding of F13A1 and Vwf 1 0.01 1.86 0.28
126 INT64892 ANTXR1 Regulation of Gtpbp4 1 0.00 0.47 0.28
127 INT355734 Pdgfb Regulation of Bdnf 1 0.22 1.5 0.27
128 INT224457 TNF Positive_regulation of Pdgfa 1 0.34 1.22 0.27
129 INT269313 Binding of Ptafr and Gp6 1 0.00 0.48 0.26
130 INT20547 IL1B Positive_regulation of Gene_expression of FN1 1 0.29 0.06 0.26
131 INT20549 IL1B Positive_regulation of FN1 1 0.19 0.06 0.26
132 INT302468 INCENP Positive_regulation of Gene_expression of MMP9 1 0.01 0.72 0.26
133 INT160225 Acot1 Negative_regulation of Ache 1 0.28 2.18 0.25
134 INT332242 Binding of Egf and Pdgfa 1 0.07 0.97 0.25
135 INT20548 IL1B Regulation of Gene_expression of FN1 1 0.19 0.07 0.25
136 INT23626 Ache Regulation of Mir343 1 0.17 0 0.24
137 INT208728 Positive_regulation of Dcn Positive_regulation of Cysltr1 1 0.02 0.3 0.24
138 INT172022 Binding of F13A1 and FN1 1 0.00 1.33 0.24
139 INT178077 EDN1 Positive_regulation of MMP9 1 0.06 0.88 0.24
140 INT208732 Dcn Positive_regulation of Cysltr1 1 0.02 0.29 0.24
141 INT205155 Negative_regulation of Binding of CD44 and MMP9 1 0.32 1.98 0.23
142 INT213061 PTGER2 Regulation of Gene_expression of MMP9 1 0.03 0.25 0.23
143 INT225117 Foxm1 Regulation of Gene_expression of FN1 1 0.01 0.4 0.22
144 INT187117 Negative_regulation of TIMP2 Negative_regulation of MMP9 1 0.36 0.6 0.22
145 INT321980 Negative_regulation of Dpp4 Negative_regulation of Positive_regulation of Ins1 1 0.16 0.81 0.22
146 INT193035 Positive_regulation of PDGFA Positive_regulation of EGF 1 0.05 0.53 0.21
147 INT193025 PDGFA Positive_regulation of EGF 1 0.05 0.53 0.21
148 INT193036 EGF Positive_regulation of PDGFA 1 0.05 0.53 0.21
149 INT193032 Positive_regulation of EGF Positive_regulation of PDGFA 1 0.05 0.53 0.21
150 INT166791 CD44 Positive_regulation of Gene_expression of PTGER1 1 0.05 0.15 0.2
151 INT137569 Comp Negative_regulation of Positive_regulation of Prl 1 0.23 0 0.2
152 INT102743 Binding of SEPT5 and Vwf 1 0.01 0.35 0.2
153 INT279107 Binding of COMP and MATN3 1 0.41 1.43 0.2
154 INT189553 DCN Negative_regulation of Transcription of VEGFA 1 0.06 0.78 0.2
155 INT137568 Comp Negative_regulation of Regulation of Prl 1 0.17 0 0.2
156 INT325470 MMP3 Positive_regulation of MMP9 1 0.17 0.9 0.2
157 INT255516 Binding of COL5A2 and GP6 1 0.01 1.17 0.2
158 INT137570 Comp Negative_regulation of Prl 1 0.17 0 0.2
159 INT166787 CD44 Negative_regulation of Gene_expression of PTGER1 1 0.04 0.15 0.2
160 INT312708 DPP8 Positive_regulation of DPP4 1 0.24 0.54 0.19
161 INT312706 DPP9 Positive_regulation of DPP4 1 0.26 0.54 0.19
162 INT335298 IRF6 Positive_regulation of MMP9 1 0.01 0.21 0.19
163 INT332245 Pdgfa Positive_regulation of Stat6 1 0.07 1.22 0.19
164 INT251665 LRP5 Negative_regulation of Ache 1 0.31 0.39 0.19
165 INT355733 Pdgfb Regulation of Transcription of Bdnf 1 0.10 0.86 0.19
166 INT50153 Positive_regulation of Bcar3 Positive_regulation of Gene_expression of Dcn 1 0.01 0.06 0.19
167 INT226071 Binding of HSD11B1 and MMP9 1 0.09 0.47 0.19
168 INT192333 PDGFA Positive_regulation of Gene_expression of FN1 2 0.11 1.26 0.18
169 INT280052 Negative_regulation of Dpp4 Positive_regulation of Zglp1 1 0.03 0.72 0.18
170 INT99006 Regulation of Binding of Selp and Itga1 1 0.06 1.36 0.18
171 INT99012 Binding of Selp and Itga1 1 0.05 1.36 0.18
172 INT284450 Edn1 Positive_regulation of Gene_expression of MMP9 1 0.01 0.3 0.18
173 INT180560 Binding of COMP and CYP27A1 1 0.12 0.47 0.18
174 INT333449 Binding of SMAD2 and SMAD4 1 0.23 0 0.17
175 INT210795 Ihh Negative_regulation of Itgb1 1 0.30 0 0.17
176 INT142332 Binding of SERPINH1 and TNNI3 1 0.03 1.05 0.17
177 INT169117 PLAU Regulation of Gene_expression of MMP9 1 0.47 0.49 0.17
178 INT355732 Pdgfb Negative_regulation of Bdnf 1 0.13 0.87 0.17
179 INT311226 DPP4 Negative_regulation of GLP1R 1 0.31 0.65 0.16
180 INT301907 Binding of THBD and VWF 1 0.02 1.71 0.16
181 INT202312 PDGFB Positive_regulation of Gene_expression of Col7a1 1 0.01 0.7 0.16
182 INT47357 Binding of FN1 and ANGPTL5 1 0.20 0.48 0.16
183 INT202311 PDGFB Positive_regulation of Gene_expression of Fn1 1 0.02 0.7 0.16
184 INT56010 Binding of FN1 and FKBPL 1 0.00 0.54 0.15
185 INT298717 Fgf2 Positive_regulation of Gene_expression of PDGFA 1 0.01 0.23 0.15
186 INT298716 Ngf Positive_regulation of Gene_expression of PDGFA 1 0.01 0.22 0.15
187 INT56008 Binding of FN1 and PTDSS1 1 0.05 0.55 0.15
188 INT180566 Binding of COMP and DMD 1 0.02 0.72 0.15
189 INT70090 TGM1 Positive_regulation of Binding of Ache 1 0.03 0.59 0.15
190 INT238331 PDGFA Regulation of Gene_expression of GOPC 1 0.04 0 0.14
191 INT58187 ITGA1 Positive_regulation of Itga3 1 0.01 1.47 0.14
192 INT238330 Binding of PDGFA and Regulation of Gene_expression of GOPC 1 0.06 0 0.14
193 INT332254 Pdgfa Positive_regulation of Stat3 1 0.02 0.52 0.14
194 INT327879 Binding of Itgb1 and Postn 1 0.02 1.05 0.14
195 INT141224 Ache Regulation of Acot1 1 0.09 0.29 0.14
196 INT27393 Tha1 Negative_regulation of Ache 1 0.15 0.24 0.14
197 INT238333 Binding of PDGFA and Regulation of Gene_expression of ADAMTS1 1 0.06 0 0.14
198 INT286900 Binding of HBM and PDGFA 1 0.04 1.08 0.14
199 INT155687 PDGFA Positive_regulation of Phosphorylation of FBRS 1 0.01 0.43 0.14
200 INT332256 Pdgfa Positive_regulation of SOAT1 1 0.01 0.51 0.14

Single Events

The table below shows the top 100 pain related interactions that have been reported for collagen binding. They are ordered first by their pain relevance and then by number of times they were reported in collagen binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4
2 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81
3 INT99610 Localization of MMP9 126 0.79 48.46 32.67
4 INT1079 Positive_regulation of Ache 104 0.70 23.52 30.28
5 INT2569 Gene_expression of Ache 120 0.78 26.29 26.89
6 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42
7 INT276 Regulation of Ache 83 0.62 16.75 25.99
8 INT14737 Gene_expression of FN1 117 0.78 78.74 18.99
9 INT9900 Positive_regulation of Vwf 80 0.69 51.85 18.13
10 INT84464 Gene_expression of DPP4 101 0.78 56.15 17.53
11 INT19071 Localization of Ache 66 0.81 5.1 16.27
12 INT1752 Negative_regulation of Ache 109 0.59 42.05 15.73
13 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7
14 INT96775 Gene_expression of Pdgfa 42 0.54 29.78 15.46
15 INT63361 Gene_expression of CD44 126 0.77 71.58 12.96
16 INT93715 Negative_regulation of MMP9 69 0.55 36.05 11.73
17 INT89282 Regulation of MMP9 39 0.60 25.45 10.34
18 INT1252 Binding of Ache 46 0.48 9.94 10.25
19 INT82829 Gene_expression of COMP 104 0.78 57 9.81
20 INT126031 Negative_regulation of Gene_expression of MMP9 40 0.57 22.71 9.79
21 INT132036 Negative_regulation of DPP4 126 0.59 63.24 9.51
22 INT9899 Gene_expression of Vwf 91 0.74 45.06 9.13
23 INT27551 Gene_expression of SERPINH1 45 0.62 42.87 9.04
24 INT187190 Positive_regulation of Localization of MMP9 27 0.68 8.1 8.93
25 INT2597 Negative_regulation of ACHE 82 0.59 46.36 8.62
26 INT621 Positive_regulation of SERPINH1 19 0.57 21.52 8.44
27 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39
28 INT60034 Positive_regulation of VWF 40 0.68 30.42 8.15
29 INT81378 Negative_regulation of Dpp4 18 0.59 7.87 7.42
30 INT14732 Positive_regulation of FN1 46 0.69 31.17 7.33
31 INT67822 Binding of SERPINH1 17 0.36 19.05 7.24
32 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9
33 INT82828 Positive_regulation of COMP 45 0.61 35.12 6.2
34 INT55655 Gene_expression of DCN 17 0.75 7.98 5.98
35 INT131378 Negative_regulation of FN1 20 0.35 33.98 5.85
36 INT13170 Gene_expression of Comp 25 0.74 8.68 5.62
37 INT32458 Gene_expression of VWF 57 0.78 28.97 5.56
38 INT99606 Negative_regulation of Localization of MMP9 23 0.57 7.15 5.47
39 INT96778 Positive_regulation of Pdgfa 22 0.46 12.7 5.31
40 INT19072 Regulation of Gene_expression of Ache 14 0.62 2.74 5.29
41 INT10888 Binding of Vwf 32 0.46 22.87 5.21
42 INT20059 Protein_catabolism of Ache 15 0.98 3.73 4.87
43 INT185877 Negative_regulation of Gene_expression of DCN 3 0.33 2.37 4.85
44 INT94453 Gene_expression of ITGB1 50 0.75 18.41 4.72
45 INT74447 Gene_expression of Vwf 39 0.76 21.96 4.66
46 INT102855 Negative_regulation of Srgn 8 0.57 0.91 4.63
47 INT1753 Gene_expression of Ache 38 0.78 15.31 4.58
48 INT46121 Negative_regulation of SERPINH1 14 0.38 10.84 4.41
49 INT74531 Regulation of PDGFB 14 0.26 7.57 4.38
50 INT57273 Positive_regulation of Gene_expression of FN1 26 0.47 17.83 4.2
51 INT11946 Transcription of Ache 18 0.69 2.62 4.13
52 INT110348 Negative_regulation of Dpp4 28 0.46 22.39 4.12
53 INT99608 Transcription of MMP9 18 0.65 9.67 4.11
54 INT96776 Positive_regulation of Gene_expression of Pdgfa 8 0.40 7.79 3.93
55 INT133312 Binding of MMP9 25 0.42 16.79 3.83
56 INT20925 Binding of ANTXR1 15 0.01 4.2 3.8
57 INT120072 Gene_expression of Smad7 38 0.74 20.87 3.69
58 INT10146 Negative_regulation of Vwf 27 0.40 17.11 3.69
59 INT13451 Positive_regulation of DPP4 23 0.68 9.33 3.62
60 INT8778 Regulation of Ache 17 0.62 3.7 3.57
61 INT162258 Negative_regulation of Gene_expression of COMP 35 0.58 19.14 3.55
62 INT70897 Positive_regulation of Gene_expression of PDGFB 15 0.57 13.04 3.52
63 INT96777 Localization of Pdgfa 12 0.79 5.86 3.52
64 INT130351 Positive_regulation of Vwf 18 0.59 5.99 3.48
65 INT70895 Localization of PDGFB 20 0.52 8.98 3.4
66 INT201959 Positive_regulation of Gene_expression of DPP4 13 0.53 6.24 3.4
67 INT118095 Regulation of COMP 7 0.43 9.69 3.33
68 INT28009 Positive_regulation of Gene_expression of Ache 15 0.70 5.46 3.26
69 INT22375 Localization of PDGFA 21 0.75 15.46 3.25
70 INT70885 Gene_expression of Pdgfb 48 0.67 42.27 3.19
71 INT279122 Regulation of Gene_expression of COMP 3 0.39 8.82 3.19
72 INT8777 Positive_regulation of Ache 25 0.68 7.77 3.18
73 INT61500 Binding of FN1 39 0.48 27.33 3.13
74 INT55409 Localization of VWF 17 0.80 8.99 3.06
75 INT19293 Protein_catabolism of FN1 7 0.95 5.15 2.97
76 INT200470 Positive_regulation of Gene_expression of COMP 13 0.69 13.73 2.93
77 INT201952 Binding of DPP4 11 0.37 8.81 2.91
78 INT22069 Positive_regulation of Localization of Ache 9 0.70 0.61 2.9
79 INT322473 Localization of DCN 1 0.03 0.76 2.9
80 INT10893 Binding of VWF 27 0.47 25.02 2.82
81 INT271599 Phosphorylation of Pdgfa 1 0.11 2.55 2.81
82 INT73836 Regulation of Comp 4 0.19 4.2 2.79
83 INT10516 Localization of Vwf 30 0.79 7.54 2.77
84 INT53755 Positive_regulation of Dcn 8 0.43 2.91 2.74
85 INT143952 Regulation of Gene_expression of MMP9 14 0.53 10.16 2.73
86 INT172963 Negative_regulation of Pdgfa 11 0.21 12.94 2.64
87 INT11892 Gene_expression of ACHE 10 0.68 1.32 2.63
88 INT12619 Positive_regulation of ANTXR1 7 0.49 3.17 2.61
89 INT74527 Positive_regulation of PDGFB 14 0.38 13.31 2.54
90 INT102856 Positive_regulation of Srgn 7 0.61 1.27 2.54
91 INT91429 Binding of CD44 34 0.41 17.67 2.51
92 INT81377 Gene_expression of Dpp4 8 0.71 5.15 2.51
93 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5
94 INT94010 Positive_regulation of Localization of VWF 9 0.70 4.23 2.5
95 INT61805 Positive_regulation of Dpp4 4 0.44 0.41 2.49
96 INT183810 Positive_regulation of Positive_regulation of MMP9 9 0.52 4.15 2.46
97 INT223080 Binding of Pdgfa 8 0.18 7.21 2.44
98 INT192337 Positive_regulation of DDR1 11 0.41 10.34 2.38
99 INT27338 Regulation of ACHE 6 0.62 1.25 2.38
100 INT68087 Regulation of Vwf 9 0.39 8.06 2.36
101 INT71273 Positive_regulation of Comp 8 0.42 3.8 2.32
102 INT84465 Localization of DPP4 8 0.75 7.28 2.29
103 INT8052 Negative_regulation of COMP 46 0.58 13.73 2.22
104 INT14890 Localization of ACHE 5 0.80 0.47 2.21
105 INT184305 Gene_expression of Comp 53 0.77 31.66 2.2
106 INT289775 Negative_regulation of Comp 4 0.41 5.69 2.2
107 INT2570 Negative_regulation of Gene_expression of Ache 13 0.43 2.88 2.18
108 INT27437 Negative_regulation of Comp 5 0.24 2.8 2.15
109 INT15090 Regulation of ANTXR1 4 0.31 2.4 2.05
110 INT103244 Protein_catabolism of MMP9 12 0.72 11.81 2.01
111 INT173851 Localization of FN1 20 0.76 13.95 1.97
112 INT57272 Negative_regulation of Gene_expression of FN1 16 0.43 11.42 1.93
113 INT47062 Gene_expression of ANTXR1 10 0.66 4.63 1.93
114 INT107178 Gene_expression of Smad4 12 0.65 9.85 1.92
115 INT38201 Negative_regulation of Localization of Ache 8 0.59 2.35 1.82
116 INT142477 Gene_expression of GP6 12 0.76 12.53 1.79
117 INT222997 Positive_regulation of Localization of FN1 4 0.14 4.26 1.78
118 INT91430 Positive_regulation of CD44 25 0.69 15.43 1.76
119 INT174924 Gene_expression of Smad7 6 0.41 3.59 1.76
120 INT211200 Regulation of SERPINH1 2 0.03 3.8 1.75
121 INT38574 Binding of Ache 9 0.47 3.64 1.74
122 INT168602 Negative_regulation of Itgb1 3 0.21 1.29 1.73
123 INT174923 Positive_regulation of Gene_expression of Smad7 3 0.37 2.3 1.73
124 INT8757 Binding of ACHE 10 0.48 5.84 1.72
125 INT6598 Gene_expression of ITGA2 9 0.46 4.88 1.72
126 INT37954 Negative_regulation of Dcn 6 0.41 0.62 1.72
127 INT102857 Phosphorylation of Srgn 1 0.72 0.26 1.71
128 INT2847 Positive_regulation of Negative_regulation of Ache 8 0.49 1.09 1.65
129 INT14891 Positive_regulation of ACHE 10 0.70 5.37 1.64
130 INT322472 Negative_regulation of Localization of DCN 1 0.02 0.47 1.64
131 INT93744 Binding of Dpp4 4 0.48 0.91 1.61
132 INT97318 Gene_expression of SPARC 11 0.67 5.07 1.59
133 INT89849 Regulation of Srgn 6 0.30 0.93 1.59
134 INT186724 Negative_regulation of Transcription of MMP9 5 0.37 1.59 1.57
135 INT103767 Phosphorylation of DDR1 6 0.20 4.67 1.56
136 INT166085 Binding of Gp6 11 0.42 3.09 1.55
137 INT295688 Positive_regulation of Regulation of MMP9 1 0.14 0.67 1.51
138 INT74528 Negative_regulation of PDGFB 11 0.40 10.34 1.48
139 INT74530 Transcription of PDGFB 7 0.65 4.56 1.47
140 INT57973 Positive_regulation of ITGB1 5 0.67 1.23 1.44
141 INT118097 Localization of COMP 18 0.70 9.99 1.42
142 INT44529 Positive_regulation of Pdgfb 11 0.43 7.98 1.36
143 INT55476 Negative_regulation of ITGA2 8 0.55 3.55 1.33
144 INT84463 Regulation of Gene_expression of DPP4 5 0.39 4.81 1.33
145 INT102852 Negative_regulation of Phosphorylation of Srgn 1 0.52 0.17 1.32
146 INT247903 Localization of ITGA1 1 0.06 5.69 1.32
147 INT102853 Positive_regulation of Phosphorylation of Srgn 1 0.61 0.17 1.31
148 INT95116 Negative_regulation of PDGFA 24 0.57 19.56 1.29
149 INT14727 Regulation of FN1 13 0.45 5.95 1.26
150 INT120076 Positive_regulation of Gene_expression of Smad7 16 0.65 11.33 1.25
151 INT192349 Negative_regulation of Gene_expression of PDGFB 5 0.31 2.64 1.25
152 INT211198 Localization of SERPINH1 2 0.66 4.33 1.25
153 INT184313 Positive_regulation of Comp 4 0.55 4.23 1.24
154 INT97909 Binding of COMP 13 0.37 5.98 1.22
155 INT1787 Binding of Antxr1 13 0.32 2.62 1.22
156 INT166082 Positive_regulation of Gp6 9 0.61 1.69 1.22
157 INT145959 Negative_regulation of DSPP 19 0.57 2.75 1.21
158 INT105571 Gene_expression of SRGN 33 0.58 14.68 1.19
159 INT37849 Negative_regulation of Negative_regulation of Ache 3 0.43 0.8 1.19
160 INT103766 Positive_regulation of Phosphorylation of DDR1 2 0.13 1.94 1.19
161 INT333999 Protein_catabolism of Comp 1 0.72 1.77 1.19
162 INT201955 Regulation of DPP4 18 0.45 11.91 1.18
163 INT29772 Positive_regulation of Positive_regulation of Ache 3 0.50 0.09 1.18
164 INT50146 Gene_expression of Dcn 18 0.51 0.9 1.17
165 INT70886 Positive_regulation of Gene_expression of Pdgfb 13 0.45 12.57 1.17
166 INT187123 Negative_regulation of Positive_regulation of MMP9 7 0.42 2.54 1.17
167 INT6599 Binding of ITGA2 4 0.35 3.6 1.16
168 INT322041 Positive_regulation of Localization of Gp6 1 0.15 0.88 1.16
169 INT72599 Negative_regulation of Gene_expression of ITGA2 2 0.09 1.3 1.15
170 INT156613 Positive_regulation of Positive_regulation of FN1 2 0.45 3.33 1.15
171 INT322043 Localization of Gp6 1 0.22 0.88 1.15
172 INT91431 Positive_regulation of Gene_expression of CD44 18 0.69 9.25 1.12
173 INT210392 Regulation of PDGFA 10 0.36 11.41 1.12
174 INT27366 Negative_regulation of Negative_regulation of Ache 4 0.43 0.29 1.12
175 INT227925 Negative_regulation of Gene_expression of ITGB1 1 0.02 2.19 1.12
176 INT143956 Regulation of Positive_regulation of MMP9 5 0.40 2.61 1.11
177 INT184720 Negative_regulation of Smad3 8 0.55 5.23 1.1
178 INT110259 Negative_regulation of Vwf 6 0.42 3.3 1.1
179 INT265491 Gene_expression of CSPG4 16 0.58 7.27 1.07
180 INT191253 Negative_regulation of DDR1 13 0.25 10.05 1.05
181 INT96579 Negative_regulation of Negative_regulation of MMP9 5 0.40 4.55 1.04
182 INT208125 Gene_expression of DDR1 10 0.06 8.15 1.03
183 INT101614 Gene_expression of Dpp4 7 0.78 2.73 1.02
184 INT117774 Phosphorylation of Ddr1 1 0.15 0.37 1.02
185 INT63354 Negative_regulation of Gene_expression of CD44 4 0.50 4.76 1.01
186 INT235793 Positive_regulation of Gene_expression of DDR1 3 0.04 4.29 1.01
187 INT89853 Gene_expression of Srgn 12 0.44 1.13 1
188 INT115987 Positive_regulation of SPARC 4 0.44 1.52 0.99
189 INT89128 Binding of DSPP 7 0.32 2.24 0.98
190 INT126416 Gene_expression of Itga1 1 0.02 0.89 0.98
191 INT157573 Localization of Vwf 9 0.69 2.93 0.97
192 INT4099 Regulation of Antxr1 2 0.17 0.09 0.97
193 INT106386 Regulation of Gene_expression of CD44 8 0.27 3.66 0.96
194 INT226478 Protein_catabolism of DPP4 11 0.85 5.52 0.95
195 INT96774 Positive_regulation of Localization of Pdgfa 3 0.69 1.21 0.95
196 INT187135 Positive_regulation of Negative_regulation of MMP9 3 0.43 1.87 0.92
197 INT188317 Positive_regulation of Gene_expression of PDGFA 15 0.46 12.7 0.91
198 INT147880 Regulation of SRGN 28 0.33 13.99 0.9
199 INT118098 Protein_catabolism of COMP 5 0.66 2.76 0.9
200 INT116459 Negative_regulation of VWF 8 0.58 5.66 0.89
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