GO:0005520

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Name insulin-like growth factor binding
Categary Function
Go Slim No
Go Link GO:0005520
Unique Molecular Interactions 158
Total Molecular Interactions 237
Total Single Events 1690
Pain Genes Associated 22

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for insulin-like growth factor binding. They are ordered first by their pain relevance and then by number of times they were reported for insulin-like growth factor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT354207 Igfbp7 Positive_regulation of Accn3 1 0.52 6.55 3.24
2 INT354210 Binding of Igfbp7 and Accn3 1 0.27 3.91 1.64
3 INT64127 Igfbp2 Regulation of Localization of Avp 1 0.39 0.19 0.9
4 INT328982 Binding of Igfals and Cts 1 0.05 0.92 0.8
5 INT328978 Binding of Igfals and Muted 1 0.02 0.85 0.73
6 INT328980 Binding of Cst7 and Igfals 1 0.06 0.85 0.73
7 INT328975 Binding of Igfals and Mup1 1 0.11 0.85 0.73
8 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66
9 INT84067 IGFBP1 Regulation of GH1 1 0.02 1.18 0.54
10 INT354218 Igfbp7 Positive_regulation of Accn1 1 0.04 0.74 0.44
11 INT133002 Mmp9 Regulation of Negative_regulation of Igfbp3 1 0.26 0.39 0.42
12 INT354221 Igfbp7 Positive_regulation of Accn2 1 0.11 0.57 0.42
13 INT342181 Binding of Igfals and Ros1 1 0.01 0.76 0.41
14 INT285725 Binding of IGF1R and INS 1 0.27 0.07 0.4
15 INT277656 Igf1 Positive_regulation of Igfbp3 1 0.01 0.4 0.34
16 INT323653 Binding of Igf1 and Igfbp1 1 0.20 1.14 0.29
17 INT220380 Il6 Positive_regulation of Gene_expression of Igfbp1 1 0.09 0.29 0.27
18 INT220381 Il1a Positive_regulation of Gene_expression of Igfbp1 1 0.01 0.28 0.27
19 INT220390 TNF Positive_regulation of Gene_expression of Igfbp1 1 0.02 0.29 0.27
20 INT92581 IGF1R Positive_regulation of Gene_expression of PTGER2 1 0.09 0.79 0.24
21 INT87750 IGFBP3 Negative_regulation of INS 1 0.11 0.86 0.23
22 INT305505 Negative_regulation of Binding of Igfals and Slc17a6 1 0.16 1.12 0.21
23 INT181765 WISP3 Regulation of Gene_expression of RHOC 1 0.49 1.46 0.21
24 INT305510 Binding of Igfals and Slc17a6 1 0.14 1.11 0.21
25 INT139454 Binding of IGF2R and Icam1 1 0.00 0.4 0.21
26 INT354220 Igfbp7 Positive_regulation of Gene_expression of Accn3 1 0.33 0.29 0.2
27 INT354211 Igfbp7 Positive_regulation of Gene_expression of Accn1 1 0.04 0.29 0.2
28 INT220146 Binding of IGF1 and IGFBP1 2 0.10 1.57 0.19
29 INT153457 Tgfb1 Positive_regulation of Gene_expression of Ctgf 1 0.13 1.15 0.19
30 INT153460 Inhba Positive_regulation of Gene_expression of Ctgf 1 0.77 1.14 0.19
31 INT354223 Binding of Car2 and Igfbp7 1 0.02 0.4 0.19
32 INT153461 Tnf Positive_regulation of Gene_expression of Ctgf 1 0.48 1.13 0.19
33 INT142853 Binding of TP53 and WISP2 1 0.33 1.43 0.19
34 INT334631 Igf1r Positive_regulation of Phosphorylation of Akt1 1 0.19 0.5 0.18
35 INT300305 Mapk14 Positive_regulation of Gene_expression of Ctgf 1 0.19 1.25 0.17
36 INT185516 Binding of Igfbp2 and Csf2 1 0.14 0.29 0.17
37 INT168941 Irs2 Regulation of Gene_expression of Igf1r 1 0.39 0.91 0.16
38 INT215901 Ins1 Positive_regulation of Igfals 1 0.02 0.81 0.15
39 INT334634 Binding of Igf1 and Igf1r 1 0.14 0.45 0.15
40 INT92582 IGF1R Positive_regulation of Transcription of PTGER2 1 0.09 0.43 0.15
41 INT153458 Ctgf Positive_regulation of Gene_expression of Il6 1 0.34 1.03 0.15
42 INT215902 Igfbp2 Positive_regulation of Igfals 1 0.15 0.8 0.15
43 INT319963 Binding of IGFALS and Vcan 1 0.03 2.99 0.13
44 INT220147 IGFBP3 Positive_regulation of IGF1 1 0.10 0.53 0.13
45 INT312218 INPP5K Positive_regulation of Protein_catabolism of IGFBP3 1 0.17 0.39 0.11
46 INT258147 IGFBP3 Negative_regulation of Hcrt 1 0.28 1.87 0.11
47 INT327792 Binding of IGFALS and Alms1 1 0.00 1.15 0.11
48 INT220149 Binding of IGF1 and IGFALS 2 0.39 0.44 0.1
49 INT277657 Igfbp1 Negative_regulation of Negative_regulation of Igf1 1 0.02 0.26 0.1
50 INT287893 VEGFA Positive_regulation of Localization of WISP1 1 0.03 1.23 0.1
51 INT234626 IGFBP3 Regulation of IGF2 1 0.15 1.31 0.1
52 INT294448 KLK4 Negative_regulation of CTGF 1 0.01 0 0.1
53 INT303815 Binding of Igfals and Tdp1 1 0.11 1.68 0.1
54 INT78446 Binding of GH1 and IGFBP3 1 0.11 0.48 0.1
55 INT354124 Binding of IGF2 and IGFBP3 1 0.01 0.45 0.09
56 INT165157 Gli1 Regulation of Igfbp5 1 0.24 0.07 0.09
57 INT174133 Binding of Igfals and Sod1 3 0.19 3 0.08
58 INT303337 Binding of SOD1 and Igfals 1 0.06 1.27 0.08
59 INT124732 Gh Regulation of Positive_regulation of IGFBP3 1 0.00 0.24 0.08
60 INT257342 Mapk4 Positive_regulation of Gene_expression of Ctgf 1 0.01 0.39 0.08
61 INT268925 Igfbp2 Negative_regulation of Phosphorylation of Mapk14 1 0.01 0.35 0.08
62 INT354213 Igfbp7 Regulation of Accn3 1 0.18 0.17 0.08
63 INT49372 Gh Positive_regulation of Gene_expression of IGFBP3 1 0.00 0.51 0.08
64 INT354113 Binding of IGFBP3 and MIR524 1 0.01 0.69 0.07
65 INT354125 Binding of IGFBP3 and MIR15B 1 0.00 0.7 0.07
66 INT73794 Binding of HSD11B1 and Igfbp1 1 0.06 1.15 0.07
67 INT354209 Igfbp7 Regulation of Positive_regulation of Accn3 1 0.29 0.15 0.07
68 INT354126 Binding of IGFALS and MIR125A 1 0.23 0.7 0.07
69 INT354111 Binding of IGFBP3 and MIR125A 1 0.11 0.7 0.07
70 INT354109 Binding of IGFALS and MIR15B 1 0.00 0.7 0.07
71 INT354116 Binding of IGFALS and MIR524 1 0.02 0.69 0.07
72 INT220724 Binding of IGFALS and SOD1 1 0.06 2.1 0.06
73 INT202244 Igfbp1 Regulation of Localization of INS 1 0.06 0 0.06
74 INT339099 ERBB2 Positive_regulation of IGF2R 1 0.33 0.67 0.06
75 INT234619 IGF1 Regulation of IGF1R 1 0.11 0.39 0.05
76 INT234624 Binding of IGF1 and IGF1R 1 0.09 0.39 0.05
77 INT287877 WNT1 Positive_regulation of Localization of WISP1 1 0.03 0.56 0.05
78 INT234620 Regulation of Binding of IGF1 and IGF1R 1 0.07 0.39 0.05
79 INT218616 Binding of IGFBP3 and INS 1 0.07 0.68 0.05
80 INT275758 Binding of xn and Igfbp3 1 0.03 5.39 0.04
81 INT258148 Gene_expression of IGFBP3 Negative_regulation of Hcrt 1 0.28 0.86 0.04
82 INT202233 IGFBP1 Regulation of IGF1 1 0.22 0.19 0.04
83 INT199212 Binding of IGFBP1 and INS 1 0.05 1.77 0.04
84 INT275754 Regulation of Binding of xn and Igfbp3 1 0.02 0.79 0.04
85 INT202245 IGFBP1 Regulation of Igfbp1 1 0.12 0.19 0.04
86 INT262198 Foxo1 Positive_regulation of Igfbp1 1 0.11 0.08 0.03
87 INT220725 Binding of IGFALS and IGHD1OR15-1A 1 0.01 1.05 0.03
88 INT234625 TP53 Positive_regulation of IGFBP3 1 0.29 0.74 0.03
89 INT258144 IGFBP3 Regulation of Gene_expression of Hcrt 1 0.30 2.23 0.03
90 INT275760 Binding of Igfbp3 and xn 1 0.00 1.32 0
91 INT234622 IGFBP3 Positive_regulation of TNFSF10 1 0.56 1.08 0
92 INT258150 IGFBP3 Regulation of Gene_expression of Gopc 1 0.05 1.22 0
93 INT145337 Binding of PYGO1 and Positive_regulation of Transcription of WISP1 1 0.07 0 0
94 INT202246 Binding of INS and Igfbp1 1 0.05 0.38 0
95 INT258146 Binding of IGFBP3 and Hcrt 1 0.23 2.04 0
96 INT210362 Binding of GPM6A and IGF2R 1 0.00 0.57 0
97 INT268517 MYC Regulation of CTGF 1 0.03 0.92 0
98 INT112085 Trpv1 Negative_regulation of Positive_regulation of Igfbp1 1 0.01 0.11 0
99 INT275733 Igfbp3 Regulation of Ins1 1 0.03 0.16 0
100 INT278498 IGFBP3 Regulation of GH1 1 0.06 0 0
101 INT334279 NR2E3 Negative_regulation of Gene_expression of IGFBP1 1 0.04 0 0
102 INT234621 CDX2 Negative_regulation of IGFBP3 1 0.38 0.8 0
103 INT114712 SRC Positive_regulation of Gene_expression of IGF1R 1 0.63 0.51 0
104 INT315065 IGF1R Regulation of Gene_expression of PAR4 1 0.37 0.53 0
105 INT258086 Binding of CSF2 and IGFBP3 1 0.05 1.18 0
106 INT258145 IGFBP3 Regulation of Hcrt 1 0.16 0.56 0
107 INT315049 IGF1R Regulation of MT1X 1 0.29 0.52 0
108 INT254906 Binding of Igfals and Chmp2b 1 0.02 0.85 0
109 INT162435 Binding of Igfals and Rapsn 1 0.19 1.34 0
110 INT215209 Binding of Igf1 and Igfbp3 1 0.11 0 0
111 INT319320 Binding of EGI and IGF1R 1 0.02 0.85 0
112 INT264679 IGFALS Positive_regulation of CTSC 1 0.02 1.68 0
113 INT258152 IGFBP3 Regulation of Transcription of Hcrt 1 0.40 0.42 0
114 INT215205 Binding of Igf2 and Igfbp3 1 0.04 0 0
115 INT258087 Negative_regulation of ANTXR2 Negative_regulation of Gene_expression of IGFBP3 1 0.04 0.29 0
116 INT141959 Binding of IGFBP3 and Igf2 1 0.01 0.09 0
117 INT234623 Binding of CDX2 and IGFBP3 1 0.32 1.71 0
118 INT202247 Binding of IGF1 and Igfbp1 1 0.16 0.21 0
119 INT258151 IGFBP3 Negative_regulation of Binding of Hcrt 1 0.28 0.49 0
120 INT114713 Binding of IGF1R and SRC 1 0.33 0.6 0
121 INT162437 Binding of Igf1 and Igfals 1 0.10 1.45 0
122 INT132069 Binding of Igf1 and Igfbp3 1 0.38 0.08 0
123 INT180858 TGFB1 Regulation of Transcription of IGFBP3 1 0.24 0.77 0
124 INT145340 Binding of BCL9 and Positive_regulation of Transcription of WISP1 1 0.43 0 0
125 INT332159 Gh Positive_regulation of Gene_expression of Igfbp3 1 0.07 1.11 0
126 INT303335 Binding of Igfals and CHMP2B 1 0.05 1.3 0
127 INT307584 Binding of EGFR and IGF1R 1 0.03 0.52 0
128 INT258149 IGFBP3 Negative_regulation of Gene_expression of Hcrt 1 0.38 1.1 0
129 INT162436 Binding of Igfals and Tardbp 1 0.16 2.68 0
130 INT278499 IGFALS Regulation of GH1 1 0.18 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for insulin-like growth factor binding. They are ordered first by their pain relevance and then by number of times they were reported in insulin-like growth factor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT48725 Gene_expression of IGFBP3 128 0.78 78.83 8.19
2 INT354202 Gene_expression of Igfbp7 1 0.45 8.29 5.58
3 INT9325 Gene_expression of Igf1r 14 0.77 8.74 5.48
4 INT49130 Positive_regulation of IGFBP3 49 0.63 27.55 4.78
5 INT9334 Positive_regulation of Igfbp1 22 0.54 9.3 4.31
6 INT48726 Gene_expression of IGFBP1 27 0.67 9.45 3.36
7 INT3463 Gene_expression of Igfals 21 0.39 21.1 2.93
8 INT191125 Gene_expression of Igfals 12 0.25 12.96 2.89
9 INT156148 Gene_expression of CTGF 16 0.78 9.98 2.87
10 INT354201 Positive_regulation of Igfbp7 1 0.40 5.32 2.87
11 INT354205 Positive_regulation of Gene_expression of Igfbp7 1 0.40 4.02 2.87
12 INT9330 Binding of Igfbp1 8 0.31 2.99 2.5
13 INT354204 Binding of Igfbp7 1 0.32 4.44 2.49
14 INT14561 Gene_expression of Igfbp1 12 0.35 6.27 2.46
15 INT51279 Regulation of IGFBP3 17 0.49 15.89 2.45
16 INT140091 Gene_expression of Ctgf 26 0.78 14.21 2.39
17 INT147417 Positive_regulation of Gene_expression of Igf1r 3 0.46 1.69 2.2
18 INT64125 Positive_regulation of Localization of Igfbp2 1 0.38 0.18 2.02
19 INT9336 Negative_regulation of Gene_expression of Igf1r 4 0.42 3.53 1.92
20 INT49371 Positive_regulation of Gene_expression of IGFBP3 27 0.70 23.13 1.9
21 INT38343 Regulation of IGFBP1 8 0.35 3.6 1.75
22 INT78938 Binding of IGFBP3 40 0.45 27.95 1.73
23 INT63272 Positive_regulation of Binding of Igfbp1 1 0.42 0 1.72
24 INT48616 Positive_regulation of IGFBP1 14 0.43 5.62 1.56
25 INT200186 Binding of Igfals 5 0.19 4.46 1.52
26 INT14562 Negative_regulation of Igfbp1 7 0.26 4.32 1.5
27 INT200185 Regulation of Igfals 10 0.26 11.4 1.47
28 INT61068 Gene_expression of Igfbp3 15 0.75 8.48 1.41
29 INT8914 Regulation of Igfbp1 10 0.45 4.44 1.41
30 INT49128 Gene_expression of IGF1R 35 0.63 23.48 1.39
31 INT200189 Negative_regulation of Igfals 7 0.24 4.19 1.39
32 INT172523 Gene_expression of WISP3 3 0.73 11.72 1.39
33 INT105569 Binding of IGFALS 13 0.25 17.31 1.36
34 INT61066 Gene_expression of Igfbp2 55 0.77 2.01 1.35
35 INT210399 Gene_expression of IGF2R 22 0.65 17.1 1.23
36 INT9323 Transcription of Igf1r 2 0.63 1.08 1.23
37 INT48728 Negative_regulation of IGFBP3 28 0.59 14.84 1.21
38 INT9319 Localization of Igfbp2 6 0.80 1.13 1.17
39 INT9318 Localization of Igfbp1 2 0.32 1.39 1.12
40 INT203372 Positive_regulation of Igfals 10 0.40 9.24 1.11
41 INT147416 Positive_regulation of Transcription of Igf1r 1 0.46 0.72 1.1
42 INT147415 Positive_regulation of Igf1r 2 0.43 0.97 1.09
43 INT82473 Positive_regulation of WISP3 1 0.00 0 1.07
44 INT92288 Binding of Igfals 3 0.13 3.14 1
45 INT240280 Gene_expression of IGFALS 14 0.42 20.38 0.95
46 INT215202 Localization of Igfbp3 3 0.62 2.5 0.91
47 INT164079 Regulation of Gene_expression of CTGF 4 0.44 2 0.9
48 INT139449 Negative_regulation of IGF2R 5 0.15 2.58 0.87
49 INT67339 Localization of IGFBP1 10 0.70 1.73 0.86
50 INT132068 Gene_expression of Igfbp3 10 0.64 3.73 0.83
51 INT192300 Positive_regulation of Gene_expression of IGFBP1 6 0.60 2.85 0.81
52 INT203311 Positive_regulation of Gene_expression of Igfals 5 0.16 6.87 0.8
53 INT64126 Negative_regulation of Igfbp2 2 0.33 0.46 0.8
54 INT277651 Positive_regulation of Localization of Igfbp1 1 0.27 0.85 0.79
55 INT114714 Binding of IGF1R 8 0.36 5.26 0.78
56 INT117849 Negative_regulation of Gene_expression of IGFBP3 8 0.39 8.75 0.75
57 INT234160 Localization of Igfals 4 0.16 3.8 0.74
58 INT277652 Negative_regulation of Localization of Igfbp3 1 0.11 0.74 0.72
59 INT49370 Localization of IGFBP3 21 0.81 9.85 0.71
60 INT160799 Regulation of IGFALS 11 0.29 9.09 0.7
61 INT84068 Negative_regulation of Gene_expression of IGFBP1 3 0.42 2.74 0.69
62 INT191123 Positive_regulation of Igfals 3 0.18 2.89 0.68
63 INT277647 Negative_regulation of Igfbp3 1 0.15 0.94 0.62
64 INT178752 Binding of IGFBP1 8 0.15 4.58 0.61
65 INT335991 Positive_regulation of Localization of Igfbp3 1 0.42 1.57 0.61
66 INT14563 Regulation of Regulation of Igfbp1 3 0.12 1.28 0.59
67 INT9331 Negative_regulation of Positive_regulation of Igfbp1 5 0.33 3 0.58
68 INT67341 Transcription of IGFBP3 27 0.72 30.46 0.57
69 INT240281 Positive_regulation of IGFALS 11 0.31 10.44 0.56
70 INT145859 Regulation of Gene_expression of Igf1r 1 0.59 1.58 0.55
71 INT277649 Localization of Igfbp3 1 0.20 0.69 0.55
72 INT142855 Negative_regulation of WISP2 1 0.59 4.17 0.54
73 INT63364 Positive_regulation of Igfbp3 9 0.64 1.92 0.53
74 INT9426 Negative_regulation of IGFBP1 5 0.37 1.35 0.51
75 INT199342 Regulation of Igfbp2 5 0.60 3.3 0.5
76 INT132996 Positive_regulation of Gene_expression of Igfbp3 4 0.49 3.2 0.5
77 INT200206 Negative_regulation of Gene_expression of Igfals 4 0.21 3.83 0.5
78 INT61067 Positive_regulation of Igfbp3 3 0.41 1.21 0.5
79 INT191122 Localization of Igfals 2 0.20 2.16 0.5
80 INT158296 Positive_regulation of Gene_expression of Ctgf 5 0.47 4.82 0.47
81 INT264689 Negative_regulation of IGFALS 10 0.33 12.58 0.45
82 INT140090 Negative_regulation of Gene_expression of Ctgf 5 0.58 1.77 0.44
83 INT199332 Binding of Igfbp2 2 0.36 1.46 0.41
84 INT354200 Negative_regulation of Igfbp7 1 0.25 0.79 0.4
85 INT139668 Binding of Igfbp2 3 0.18 0.98 0.39
86 INT124719 Regulation of Regulation of IGFBP3 3 0.36 2.02 0.38
87 INT294079 Protein_catabolism of IGFBP3 3 0.27 1.89 0.38
88 INT168940 Phosphorylation of Igf1r 1 0.77 2.18 0.38
89 INT132995 Negative_regulation of Igfbp3 1 0.44 0.36 0.38
90 INT268558 Regulation of CTGF 5 0.23 4.7 0.37
91 INT220374 Positive_regulation of Gene_expression of Igfbp1 2 0.27 1.03 0.37
92 INT82471 Negative_regulation of Positive_regulation of WISP3 1 0.00 0 0.37
93 INT139450 Binding of IGF2R 3 0.19 1.75 0.36
94 INT82472 Positive_regulation of Positive_regulation of WISP3 1 0.00 0 0.36
95 INT119248 Binding of Ctgf 1 0.35 1.5 0.35
96 INT167571 Regulation of Gene_expression of Igfbp1 2 0.18 0.65 0.34
97 INT153465 Regulation of Gene_expression of Ctgf 3 0.61 2.5 0.33
98 INT210766 Gene_expression of Igf1r 6 0.65 2.15 0.31
99 INT61065 Positive_regulation of Igfbp2 9 0.69 1.13 0.3
100 INT277650 Negative_regulation of Transcription of Igfbp3 1 0.11 0.24 0.3
101 INT277654 Transcription of Igfbp3 1 0.18 0.24 0.3
102 INT240278 Localization of IGFALS 11 0.53 9.44 0.29
103 INT9326 Regulation of Igfbp2 4 0.61 0.99 0.29
104 INT168140 Regulation of Ctgf 2 0.60 2.15 0.29
105 INT219162 Localization of CTGF 1 0.50 2.62 0.29
106 INT191124 Positive_regulation of Gene_expression of Igfals 1 0.03 1.8 0.29
107 INT294476 Negative_regulation of CTGF 1 0.27 1.86 0.29
108 INT164080 Negative_regulation of Gene_expression of CTGF 1 0.41 0.51 0.29
109 INT199343 Positive_regulation of Igfbp2 8 0.67 7.85 0.28
110 INT161410 Transcription of WISP3 1 0.67 1.17 0.28
111 INT104588 Phosphorylation of IGFBP1 4 0.70 0.47 0.27
112 INT145860 Negative_regulation of Gene_expression of Igfbp3 2 0.35 1.52 0.27
113 INT136840 Positive_regulation of Ctgf 2 0.35 1.34 0.27
114 INT264686 Positive_regulation of Gene_expression of IGFALS 2 0.28 2.21 0.27
115 INT268924 Negative_regulation of Gene_expression of Igfbp2 1 0.02 0.8 0.27
116 INT124720 Regulation of Gene_expression of IGFBP3 2 0.39 3.1 0.26
117 INT132992 Negative_regulation of Gene_expression of Igfbp3 1 0.37 0.84 0.26
118 INT268478 Negative_regulation of Positive_regulation of Igfbp5 1 0.26 0.64 0.26
119 INT105891 Negative_regulation of Positive_regulation of IGFBP1 2 0.12 0.66 0.25
120 INT268477 Positive_regulation of Igfbp5 1 0.31 0.63 0.25
121 INT181779 Positive_regulation of Gene_expression of WISP3 1 0.57 1.62 0.25
122 INT354203 Regulation of Igfbp7 1 0.26 0.38 0.24
123 INT258095 Binding of Igfbp3 4 0.29 2.86 0.23
124 INT199333 Gene_expression of Igfbp2 8 0.65 9.3 0.21
125 INT192958 Negative_regulation of IGF1R 8 0.30 6.35 0.21
126 INT250517 Phosphorylation of Igf1r 5 0.79 1.21 0.21
127 INT213792 Positive_regulation of Igf1r 3 0.45 1 0.2
128 INT132067 Binding of Igfbp3 7 0.33 2.51 0.19
129 INT142856 Gene_expression of WISP2 3 0.60 1.44 0.19
130 INT277648 Regulation of Localization of Igfbp1 1 0.11 0.23 0.19
131 INT168938 Negative_regulation of Phosphorylation of Igf1r 1 0.40 1.1 0.19
132 INT142857 Transcription of WISP2 1 0.53 1.34 0.19
133 INT215200 Regulation of Igfbp3 3 0.35 0.71 0.18
134 INT165152 Gene_expression of Igfbp5 1 0.70 0.13 0.18
135 INT275741 Positive_regulation of Gene_expression of Igfbp3 2 0.25 1.3 0.17
136 INT9332 Transcription of Igfbp1 2 0.54 0.47 0.17
137 INT9322 Transcription of Igfbp2 2 0.44 0.44 0.17
138 INT277469 Regulation of Gene_expression of IGF2R 1 0.22 0 0.17
139 INT72394 Gene_expression of Igfbp1 1 0.75 1.08 0.17
140 INT219160 Positive_regulation of CTGF 2 0.29 2.95 0.15
141 INT168939 Negative_regulation of Igf1r 1 0.40 1.01 0.15
142 INT294084 Regulation of Negative_regulation of IGFBP3 1 0.08 0.81 0.14
143 INT327784 Regulation of Gene_expression of IGFALS 1 0.07 1.21 0.13
144 INT153463 Localization of Ctgf 1 0.65 0.97 0.13
145 INT9320 Regulation of Transcription of Igf1r 1 0.04 0.36 0.13
146 INT9333 Regulation of Igf1r 1 0.07 0.36 0.13
147 INT285623 Regulation of Binding of Igfbp2 1 0.34 0.56 0.13
148 INT285629 Regulation of Binding of Igfbp3 1 0.35 0.56 0.13
149 INT268476 Protein_catabolism of Igfbp5 1 0.40 0.25 0.13
150 INT92590 Positive_regulation of Gene_expression of IGF1R 3 0.57 2.31 0.12
151 INT335980 Regulation of Igfals 1 0.17 2.26 0.12
152 INT92589 Positive_regulation of IGF1R 4 0.38 0.98 0.11
153 INT210393 Positive_regulation of Gene_expression of IGF2R 2 0.26 1.29 0.11
154 INT192299 Regulation of Gene_expression of IGFBP1 2 0.39 0.24 0.1
155 INT142854 Binding of WISP2 1 0.37 0.71 0.1
156 INT312954 Regulation of Binding of IGF1R 1 0.13 0 0.1
157 INT142474 Regulation of Localization of IGFBP1 1 0.14 0.25 0.1
158 INT163310 Regulation of Phosphorylation of IGFBP1 1 0.17 0.27 0.1
159 INT139396 Regulation of WISP1 1 0.55 0.29 0.1
160 INT250519 Negative_regulation of Igf1r 5 0.42 2.7 0.09
161 INT75111 Negative_regulation of Positive_regulation of IGFBP3 2 0.40 3.44 0.09
162 INT199348 Negative_regulation of Igfbp2 1 0.41 0.2 0.09
163 INT165155 Regulation of Igfbp5 1 0.55 0.07 0.09
164 INT92587 Positive_regulation of Positive_regulation of IGF1R 1 0.38 0.38 0.08
165 INT349623 Negative_regulation of Binding of Igf1r 1 0.39 0.51 0.08
166 INT250508 Negative_regulation of Gene_expression of Igf1r 1 0.42 2.01 0.08
167 INT349620 Binding of Igf1r 1 0.34 0.51 0.08
168 INT156147 Positive_regulation of Gene_expression of CTGF 1 0.70 0.14 0.07
169 INT124721 Regulation of Localization of IGFBP3 1 0.10 0.23 0.07
170 INT234462 Phosphorylation of IGF1R 2 0.42 0.99 0.06
171 INT234630 Negative_regulation of Transcription of IGFBP3 1 0.43 2.1 0.06
172 INT132066 Regulation of Igfbp3 1 0.56 0.09 0.06
173 INT339196 Positive_regulation of IGF2R 1 0.39 0.66 0.06
174 INT234629 Regulation of Transcription of IGFBP3 3 0.40 3.29 0.05
175 INT173650 Localization of WISP1 2 0.15 0.65 0.05
176 INT172522 Negative_regulation of Gene_expression of WISP3 1 0.26 1.46 0.05
177 INT275737 Positive_regulation of Binding of Igfbp3 1 0.18 0 0.05
178 INT315099 Localization of IGF1R 2 0.55 0.36 0.04
179 INT231433 Positive_regulation of Binding of IGFBP3 2 0.34 0.6 0.04
180 INT271818 Negative_regulation of Ctgf 1 0.21 0.41 0.04
181 INT239092 Positive_regulation of Binding of IGFBP1 1 0.04 0.6 0.04
182 INT319330 Transcription of IGF2R 1 0.33 1.34 0.04
183 INT234471 Negative_regulation of Phosphorylation of IGF1R 1 0.04 0.76 0.03
184 INT325289 Regulation of IGF2R 1 0.06 1.12 0.03
185 INT278502 Positive_regulation of Positive_regulation of IGFBP3 1 0.26 0.4 0.03
186 INT210311 Regulation of Gene_expression of Igfbp2 1 0.61 0 0.03
187 INT334692 Localization of Igf1r 1 0.09 0.89 0.03
188 INT139389 Gene_expression of WISP1 4 0.70 0.5 0
189 INT222308 Regulation of IGF1R 3 0.12 2.18 0
190 INT339214 Negative_regulation of Gene_expression of IGF1R 2 0.22 0.4 0
191 INT282728 Regulation of Igf1r 2 0.18 0.92 0
192 INT180890 Positive_regulation of Transcription of IGFBP3 2 0.47 2.18 0
193 INT199356 Positive_regulation of Gene_expression of Igfbp2 1 0.48 2.86 0
194 INT321694 Positive_regulation of Phosphorylation of Igf1r 1 0.27 0.2 0
195 INT338259 Positive_regulation of Binding of IGF1R 1 0.27 1.38 0
196 INT210310 Positive_regulation of Gene_expression of Igfbp2 1 0.69 0.07 0
197 INT199344 Negative_regulation of Positive_regulation of Igfbp2 1 0.41 0.87 0
198 INT174128 Regulation of Gene_expression of Igfals 1 0.06 0.41 0
199 INT139398 Regulation of Gene_expression of WISP1 1 0.40 0.1 0
200 INT210309 Regulation of Positive_regulation of Igfbp2 1 0.45 0 0
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