GO:0005521

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Name lamin binding
Categary Function
Go Slim No
Go Link GO:0005521
Unique Molecular Interactions 68
Total Molecular Interactions 88
Total Single Events 739
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for lamin binding. They are ordered first by their pain relevance and then by number of times they were reported for lamin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT147652 PLCB1 Negative_regulation of Positive_regulation of TRPV1 1 0.27 0.92 1.62
2 INT28992 Tmpo Positive_regulation of Pomc 1 0.36 3.18 1.41
3 INT128861 LBR Positive_regulation of Positive_regulation of OPRM1 1 0.19 0.36 0.75
4 INT8980 Gal Regulation of PLCB1 1 0.18 0.13 0.68
5 INT170558 Binding of Myoc and Narf 1 0.04 3.03 0.63
6 INT96765 LBR Positive_regulation of Gene_expression of TP53INP2 1 0.11 0.5 0.62
7 INT176371 LBR Positive_regulation of IL12A 1 0.04 1.22 0.55
8 INT176367 LBR Positive_regulation of IFNA1 1 0.02 1.22 0.55
9 INT48102 Positive_regulation of LBR Positive_regulation of Positive_regulation of OR7A5 1 0.21 0 0.48
10 INT176366 LBR Regulation of IFNA1 1 0.04 0.91 0.46
11 INT176361 Positive_regulation of LBR Positive_regulation of Gene_expression of IL18 1 0.10 0.84 0.39
12 INT28991 Tmpo Positive_regulation of Gene_expression of Pomc 1 0.34 0.82 0.37
13 INT176363 IFNA1 Regulation of Positive_regulation of LBR 1 0.04 0.69 0.34
14 INT307017 LBR Positive_regulation of Gene_expression of TNF 1 0.02 0.58 0.32
15 INT307014 LBR Positive_regulation of Gene_expression of IL6 1 0.01 0.58 0.32
16 INT21321 Pomc Positive_regulation of LBR 1 0.04 0 0.31
17 INT170560 Binding of Renbp and Narf 1 0.01 1.69 0.27
18 INT157957 Ppyr1 Negative_regulation of Phosphorylation of PLCB1 1 0.00 0.24 0.24
19 INT118857 PLCB1 Regulation of Phosphorylation of SRC 1 0.01 0.15 0.24
20 INT269561 TMPO Positive_regulation of RHOA 1 0.22 0 0.23
21 INT269322 TMPO Positive_regulation of Positive_regulation of NOS1 1 0.03 0 0.18
22 INT182326 LBR Positive_regulation of Gene_expression of Birc5 1 0.00 0.46 0.17
23 INT269325 DYNC1I2 Positive_regulation of TMPO 1 0.01 0 0.15
24 INT59808 Binding of AGT and PLCB1 1 0.02 0 0.13
25 INT269326 PRKCA Positive_regulation of Localization of TMPO 1 0.01 0 0.13
26 INT269336 PRKCA Regulation of Localization of TMPO 1 0.01 0.12 0.13
27 INT59809 AGT Positive_regulation of PLCB1 1 0.03 0 0.13
28 INT59807 ADRA1D Positive_regulation of PLCB1 1 0.33 0 0.13
29 INT269332 Binding of NOS3 and TMPO 1 0.01 0 0.12
30 INT39207 LBR Positive_regulation of Gene_expression of IL2 1 0.23 0 0.11
31 INT269415 Prkaca Regulation of Localization of TMPO 1 0.00 0 0.1
32 INT214752 EDNRA Positive_regulation of PLCB1 1 0.02 0 0.08
33 INT269324 Regulation of TNIP3 Negative_regulation of TMPO 1 0.00 0 0.08
34 INT115933 U Regulation of PLCB1 1 0.00 0.3 0.08
35 INT269327 PRKG1 Regulation of Localization of TMPO 1 0.02 0 0.08
36 INT269323 TNIP3 Negative_regulation of TMPO 1 0.00 0 0.07
37 INT269568 PTGIR Regulation of TMPO 1 0.01 0.06 0.05
38 INT269556 PTGIR Negative_regulation of TMPO 1 0.01 0 0.05
39 INT237085 Binding of Bnip3l and Vcp 1 0.31 3.53 0.05
40 INT307007 MT1JP Positive_regulation of Localization of LBR 1 0.01 0 0.05
41 INT323707 LBR Positive_regulation of MIR146A 1 0.02 0.1 0.03
42 INT269596 TMPO Positive_regulation of Localization of CA2 1 0.12 0.06 0.03
43 INT237086 Binding of Bnip3l and Itm2b 1 0.28 1.66 0.03
44 INT237090 Binding of App and Bnip3l 1 0.18 1.66 0.03
45 INT174204 Binding of SYNE1 and IL19 1 0.06 0.47 0.03
46 INT237089 Binding of Bnip3l and Atp6v0a4 1 0.12 1.67 0.03
47 INT269589 MAPKAP1 Regulation of TMPO 1 0.03 0.07 0.03
48 INT269567 TMPO Positive_regulation of PTGDS 1 0.07 0 0
49 INT269586 Negative_regulation of TMPO Positive_regulation of RHOA 1 0.14 0 0
50 INT269552 TMPO Regulation of Localization of CA2 1 0.11 0 0
51 INT170562 Car2 Regulation of Narf 1 0.05 1.17 0
52 INT170559 Narf Regulation of Gene_expression of Car2 1 0.05 1.01 0
53 INT269580 TMPO Positive_regulation of GOPC 1 0.05 0 0
54 INT269565 Binding of TMPO and MAPKAP1 1 0.02 0.06 0
55 INT269553 TMPO Regulation of PTGIR 1 0.01 0 0
56 INT269588 PRKG1 Positive_regulation of Phosphorylation of TMPO 1 0.11 0 0
57 INT269590 Positive_regulation of TMPO Positive_regulation of RHOA 1 0.16 0 0
58 INT269583 TMPO Positive_regulation of Gene_expression of RHOA 1 0.16 0.14 0
59 INT269550 TMPO Positive_regulation of Phosphorylation of PRKG1 1 0.11 0 0
60 INT269574 Regulation of TMPO Positive_regulation of RHOA 1 0.20 0 0
61 INT269560 TMPO Regulation of Phosphorylation of CFL1 1 0.07 0 0
62 INT269595 TMPO Positive_regulation of Phosphorylation of CFL1 1 0.07 0 0
63 INT269559 PTGIR Regulation of Phosphorylation of TMPO 1 0.01 0.06 0
64 INT269563 GOPC Positive_regulation of Gene_expression of TMPO 1 0.05 0 0
65 INT269577 Binding of PTGIR and TMPO 1 0.01 0 0
66 INT269582 Negative_regulation of TMPO Positive_regulation of PTGDS 1 0.06 0 0
67 INT269558 Gene_expression of PRKG1 Positive_regulation of Phosphorylation of TMPO 1 0.11 0 0
68 INT170561 Renbp Regulation of Narf 1 0.01 3.86 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for lamin binding. They are ordered first by their pain relevance and then by number of times they were reported in lamin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT39244 Gene_expression of TMPO 137 0.77 14.55 11.83
2 INT39242 Negative_regulation of TMPO 29 0.58 5.15 7.04
3 INT83728 Localization of TMPO 42 0.46 0.46 5.06
4 INT178751 Positive_regulation of TMPO 51 0.44 1.47 4.41
5 INT170553 Negative_regulation of Narf 12 0.05 16.19 3.78
6 INT48106 Positive_regulation of LBR 11 0.49 5.14 2.86
7 INT11139 Gene_expression of LBR 20 0.75 5.13 2.78
8 INT39243 Regulation of TMPO 20 0.61 5.66 2.67
9 INT269402 Phosphorylation of TMPO 17 0.32 0.17 2.36
10 INT59818 Negative_regulation of PLCB1 7 0.57 2.24 2.28
11 INT269372 Positive_regulation of Localization of TMPO 19 0.23 0.25 2.23
12 INT170548 Regulation of Narf 1 0.06 34.17 2.18
13 INT44773 Negative_regulation of LBR 6 0.57 2.32 2.03
14 INT170556 Gene_expression of Narf 1 0.06 17.85 1.96
15 INT269406 Binding of TMPO 35 0.31 1.43 1.82
16 INT170547 Positive_regulation of Narf 29 0.06 64.48 1.61
17 INT144380 Gene_expression of SYNE1 12 0.58 6.99 1.55
18 INT269381 Positive_regulation of Phosphorylation of TMPO 9 0.20 0 1.27
19 INT59815 Positive_regulation of PLCB1 9 0.67 1.12 1.22
20 INT269411 Positive_regulation of Gene_expression of TMPO 9 0.23 0.65 1.22
21 INT170550 Binding of Narf 9 0.04 14.89 1.18
22 INT28643 Positive_regulation of Gene_expression of LBR 3 0.11 2.43 1.16
23 INT31805 Localization of LBR 3 0.73 1.23 1.13
24 INT71378 Transcription of LBR 2 0.07 1.34 1.03
25 INT269384 Negative_regulation of Gene_expression of TMPO 10 0.23 0.47 0.97
26 INT44772 Negative_regulation of Negative_regulation of LBR 2 0.42 0.38 0.92
27 INT269413 Regulation of Localization of TMPO 7 0.18 0 0.86
28 INT271160 Negative_regulation of SYNE1 1 0.00 0.67 0.81
29 INT269401 Regulation of Gene_expression of TMPO 8 0.18 2.89 0.78
30 INT59817 Gene_expression of PLCB1 4 0.75 0.73 0.65
31 INT46148 Binding of LBR 5 0.31 1.58 0.64
32 INT144378 Binding of SYNE1 1 0.28 1.01 0.64
33 INT307027 Positive_regulation of Localization of LBR 1 0.05 0.82 0.61
34 INT269379 Negative_regulation of Localization of TMPO 5 0.17 0 0.56
35 INT176375 Positive_regulation of Positive_regulation of LBR 1 0.10 1.12 0.53
36 INT269414 Regulation of Phosphorylation of TMPO 5 0.18 0.11 0.51
37 INT271161 Negative_regulation of Negative_regulation of SYNE1 1 0.00 0.24 0.47
38 INT157955 Phosphorylation of PLCB1 1 0.01 0.46 0.46
39 INT269373 Positive_regulation of Positive_regulation of TMPO 3 0.20 0.06 0.38
40 INT170549 Localization of Narf 1 0.07 2.67 0.38
41 INT3044 Regulation of LBR 2 0.44 0.1 0.35
42 INT74604 Negative_regulation of Gene_expression of PLCB1 1 0.41 0.25 0.35
43 INT59816 Positive_regulation of Gene_expression of PLCB1 2 0.49 0.22 0.31
44 INT269367 Regulation of Negative_regulation of TMPO 3 0.18 0 0.29
45 INT235857 Binding of PLCB1 1 0.36 0.35 0.29
46 INT157956 Regulation of Phosphorylation of PLCB1 1 0.00 0.22 0.22
47 INT269376 Negative_regulation of Phosphorylation of TMPO 2 0.17 0.11 0.21
48 INT269394 Negative_regulation of Positive_regulation of TMPO 2 0.17 0.28 0.2
49 INT74602 Negative_regulation of Positive_regulation of PLCB1 1 0.41 0.25 0.19
50 INT32051 Localization of Tmpo 1 0.02 0 0.19
51 INT269389 Protein_catabolism of TMPO 1 0.06 0 0.15
52 INT269375 Positive_regulation of Binding of TMPO 1 0.04 0 0.13
53 INT64474 Regulation of Positive_regulation of LBR 1 0.22 0.08 0.13
54 INT269398 Regulation of Binding of TMPO 2 0.18 0 0.12
55 INT269390 Regulation of Positive_regulation of TMPO 6 0.26 0.4 0.11
56 INT59820 Regulation of Gene_expression of PLCB1 1 0.44 0 0.09
57 INT174243 Positive_regulation of SYNE1 1 0.06 0.35 0.09
58 INT55486 Negative_regulation of Positive_regulation of LBR 1 0.41 1.07 0.08
59 INT115930 Regulation of PLCB1 1 0.02 0.29 0.08
60 INT74606 Regulation of Negative_regulation of PLCB1 1 0.44 0.19 0.07
61 INT269609 Transcription of TMPO 1 0.27 0 0.07
62 INT269616 Positive_regulation of Transcription of TMPO 1 0.20 0 0.07
63 INT303974 Phosphorylation of LBR 2 0.79 0.24 0.06
64 INT269603 Regulation of Regulation of TMPO 1 0.24 0.45 0.06
65 INT303973 Negative_regulation of Phosphorylation of LBR 1 0.41 0.14 0.06
66 INT59814 Positive_regulation of Negative_regulation of PLCB1 1 0.45 0 0.04
67 INT269639 Positive_regulation of Negative_regulation of TMPO 1 0.20 0 0.04
68 INT269405 Negative_regulation of Negative_regulation of TMPO 1 0.04 0 0.03
69 INT237065 Positive_regulation of Bnip3l 1 0.37 1.63 0.03
70 INT170551 Positive_regulation of Positive_regulation of Narf 2 0.05 3.83 0
71 INT330661 Regulation of Phosphorylation of LBR 1 0.03 0.1 0
72 INT247753 Localization of SYNE1 1 0.68 0 0
73 INT208047 Regulation of SYNE1 1 0.00 0.64 0
74 INT170545 Regulation of Positive_regulation of Narf 1 0.04 1.44 0
75 INT298394 Positive_regulation of Binding of LBR 1 0.05 0.31 0
76 INT269620 Negative_regulation of Binding of TMPO 1 0.17 0 0
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