GO:0005523

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Name tropomyosin binding
Categary Function
Go Slim No
Go Link GO:0005523
Unique Molecular Interactions 48
Total Molecular Interactions 55
Total Single Events 712
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for tropomyosin binding. They are ordered first by their pain relevance and then by number of times they were reported for tropomyosin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT349608 Binding of DIO2 and LMOD1 1 0.23 0.41 2.01
2 INT2685 S100A6 Positive_regulation of Regulation of Thra 1 0.47 0.09 0.58
3 INT2684 S100A6 Regulation of Regulation of Thra 1 0.45 0.09 0.58
4 INT87613 LMOD1 Positive_regulation of Fos 1 0.00 0.15 0.56
5 INT261497 Binding of PTGDR and LMOD1 1 0.00 0.51 0.54
6 INT92743 Binding of NF2 and LMOD1 1 0.00 0.08 0.46
7 INT229105 Binding of GRIN1 and LMOD1 1 0.07 0.15 0.4
8 INT175016 Binding of REN and S100A6 2 0.11 1.13 0.37
9 INT339000 Binding of LMOD1 and GSX1 1 0.01 0 0.3
10 INT175017 Negative_regulation of Binding of REN and S100A6 1 0.13 0.45 0.29
11 INT175018 Positive_regulation of Binding of REN and S100A6 1 0.15 0.45 0.29
12 INT130740 Regulation of Binding of Tnnt2 and Mb 1 0.00 0.47 0.19
13 INT130741 Binding of Tnnt2 and Mb 1 0.01 0.47 0.19
14 INT294108 Binding of DNASE1L3 and LMOD1 1 0.08 0 0.14
15 INT266384 Binding of Ager and S100a6 1 0.01 1.32 0.11
16 INT266385 S100a6 Positive_regulation of Ager 1 0.01 0.84 0.1
17 INT168856 Binding of Tnnt2 and Fabp3 1 0.05 0.57 0.09
18 INT271347 Negative_regulation of Binding of TNNT2 and ACCS 1 0.01 0.67 0.08
19 INT271346 Binding of TNNT2 and ACCS 1 0.01 0.67 0.08
20 INT277010 Binding of PAPPA and TNNT1 1 0.24 0.99 0.07
21 INT266389 Binding of C2 and S100a6 1 0.04 0.5 0.07
22 INT266390 Binding of S100a6 and Trp53 1 0.04 0.51 0.07
23 INT266388 S100a6 Negative_regulation of Mapk8 1 0.03 0.49 0.06
24 INT197617 Binding of S100a6 and Rb1 1 0.03 0 0.06
25 INT353203 TNNT1 Regulation of Tnnt3 1 0.26 0.19 0.04
26 INT353204 TNNT1 Regulation of Chkb 1 0.08 0.19 0.04
27 INT266415 Binding of ROS1 and S100a6 1 0.02 0.82 0.03
28 INT283862 Binding of CALD1 and MYH14 1 0.02 0 0
29 INT269772 Binding of NOVA2 and LMOD1 1 0.06 0 0
30 INT285231 Binding of CHKB and TNNT1 1 0.15 0.05 0
31 INT197907 Dlst Regulation of S100a6 1 0.10 0 0
32 INT197902 Regulation of Oxt Regulation of S100a6 1 0.08 0 0
33 INT134638 Tnnt3 Positive_regulation of Regulation of Mb 1 0.00 0.23 0
34 INT322249 Binding of Hcm and Tnnt2 1 0.11 0.86 0
35 INT197913 Oxt Regulation of Gene_expression of S100a6 1 0.08 0 0
36 INT197904 Dlst Positive_regulation of Positive_regulation of S100a6 1 0.09 0 0
37 INT197898 Dlst Regulation of Gene_expression of S100a6 1 0.14 0 0
38 INT197905 Oxt Regulation of S100a6 1 0.08 0 0
39 INT277310 Binding of Tnnt2 and Mbnl1 1 0.18 1.1 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for tropomyosin binding. They are ordered first by their pain relevance and then by number of times they were reported in tropomyosin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT86464 Binding of LMOD1 31 0.44 10.23 10.46
2 INT57424 Positive_regulation of TNNT1 42 0.67 31.84 9.7
3 INT49566 Positive_regulation of LMOD1 16 0.61 5.74 5.92
4 INT63772 Gene_expression of LMOD1 26 0.75 3.77 5.84
5 INT63957 Positive_regulation of Tnnt2 33 0.69 18.56 5.41
6 INT49568 Regulation of LMOD1 6 0.43 2.57 5
7 INT51030 Negative_regulation of LMOD1 9 0.44 5.83 4.58
8 INT68189 Gene_expression of TNNT1 27 0.75 14.87 4.03
9 INT26368 Positive_regulation of S100A6 30 0.45 9.72 3.89
10 INT85985 Localization of TNNT1 10 0.78 6.66 3.26
11 INT92756 Negative_regulation of Binding of LMOD1 4 0.54 3.83 3.08
12 INT76191 Regulation of TNNT1 9 0.60 5.4 2.9
13 INT18848 Localization of LMOD1 5 0.69 1 2.49
14 INT168097 Transcription of Tnnt2 1 0.07 2.12 2.47
15 INT81247 Gene_expression of Tnnt2 9 0.31 2.06 2.37
16 INT118896 Regulation of Tnnt2 4 0.44 2.94 2.09
17 INT26369 Gene_expression of S100A6 19 0.65 5.39 1.81
18 INT56216 Positive_regulation of Tnnt3 10 0.67 6.72 1.81
19 INT68187 Gene_expression of TNNT2 21 0.67 10.22 1.64
20 INT309257 Transcription of LMOD1 3 0.36 1.71 1.57
21 INT49706 Positive_regulation of TNNT2 22 0.69 12.65 1.56
22 INT72680 Regulation of Gene_expression of LMOD1 3 0.48 0.83 1.46
23 INT72458 Positive_regulation of Tnnt2 5 0.69 5.59 1.38
24 INT47434 Gene_expression of Tnnt2 14 0.60 10.4 1.37
25 INT109688 Binding of TNNT1 6 0.47 4.01 1.25
26 INT96117 Negative_regulation of Tnnt2 3 0.13 1.61 1.1
27 INT293678 Positive_regulation of Gene_expression of S100A6 1 0.34 2.42 1.04
28 INT43919 Negative_regulation of S100A6 19 0.16 4.45 0.96
29 INT73433 Gene_expression of S100a6 10 0.71 2.74 0.76
30 INT56214 Localization of Tnnt3 4 0.77 4.54 0.75
31 INT349613 Regulation of Binding of LMOD1 1 0.41 0.53 0.74
32 INT63958 Regulation of Tnnt2 7 0.45 5.36 0.7
33 INT191706 Positive_regulation of Gene_expression of TNNT1 5 0.49 3.61 0.64
34 INT64536 Binding of Tnnt2 4 0.32 2.47 0.64
35 INT349609 Regulation of Regulation of LMOD1 1 0.41 0.65 0.63
36 INT309253 Negative_regulation of Transcription of LMOD1 1 0.03 0.2 0.57
37 INT50879 Regulation of TNNT2 3 0.26 1.53 0.55
38 INT134486 Positive_regulation of Positive_regulation of LMOD1 2 0.33 0.15 0.55
39 INT339004 Regulation of Negative_regulation of LMOD1 1 0.09 1.46 0.52
40 INT143162 Gene_expression of S100a6 7 0.78 5.86 0.49
41 INT106843 Regulation of Tnnt3 2 0.61 1.76 0.48
42 INT56215 Positive_regulation of Positive_regulation of Tnnt3 2 0.45 1.26 0.47
43 INT87460 Gene_expression of Tnnt3 4 0.60 2.71 0.46
44 INT349612 Positive_regulation of Localization of LMOD1 1 0.46 0 0.46
45 INT85589 Positive_regulation of Positive_regulation of TNNT1 3 0.49 2.5 0.44
46 INT110498 Localization of S100a6 1 0.31 1.57 0.44
47 INT43387 Regulation of S100A6 2 0.15 0.4 0.4
48 INT64537 Localization of Tnnt2 5 0.76 1.57 0.37
49 INT309686 Negative_regulation of Gene_expression of LMOD1 2 0.11 0 0.37
50 INT80914 Negative_regulation of TNNT1 1 0.41 1.33 0.37
51 INT73898 Positive_regulation of Regulation of Tnnt2 1 0.44 0.83 0.37
52 INT213648 Phosphorylation of S100A6 2 0.30 1.43 0.36
53 INT56212 Regulation of Localization of Tnnt3 1 0.21 0.82 0.35
54 INT56213 Positive_regulation of Localization of Tnnt3 1 0.40 0.8 0.35
55 INT143165 Positive_regulation of S100a6 8 0.69 3.5 0.34
56 INT49302 Localization of TNNT2 6 0.78 3.1 0.34
57 INT344080 Negative_regulation of Localization of LMOD1 1 0.03 0.64 0.34
58 INT140475 Positive_regulation of Binding of TNNT1 1 0.49 0.85 0.34
59 INT288041 Negative_regulation of Positive_regulation of TNNT1 1 0.41 0.15 0.32
60 INT197585 Positive_regulation of S100a6 3 0.43 1.67 0.29
61 INT143164 Positive_regulation of Gene_expression of S100a6 3 0.69 2.33 0.25
62 INT310565 Regulation of Localization of TNNT1 1 0.44 0.65 0.25
63 INT230957 Positive_regulation of CALD1 3 0.45 1.88 0.24
64 INT213438 Gene_expression of CALD1 2 0.31 0.39 0.21
65 INT113131 Transcription of TNNT1 1 0.52 0.73 0.21
66 INT73435 Negative_regulation of S100a6 1 0.21 0.26 0.2
67 INT106842 Negative_regulation of Localization of Tnnt3 1 0.51 0.2 0.2
68 INT143163 Regulation of S100a6 2 0.45 1.47 0.18
69 INT349610 Positive_regulation of Binding of LMOD1 1 0.43 0.16 0.18
70 INT50880 Positive_regulation of Positive_regulation of TNNT2 1 0.49 0.53 0.17
71 INT293679 Positive_regulation of Positive_regulation of S100A6 2 0.24 1.19 0.14
72 INT238423 Negative_regulation of Negative_regulation of LMOD1 1 0.07 0.36 0.14
73 INT284805 Negative_regulation of Localization of TNNT2 1 0.42 0.77 0.13
74 INT287862 Phosphorylation of Tnnt2 1 0.42 0.07 0.12
75 INT311275 Regulation of Gene_expression of Tnnt2 2 0.34 1.33 0.1
76 INT121284 Positive_regulation of Gene_expression of Tnnt2 2 0.46 0.89 0.1
77 INT121285 Regulation of Positive_regulation of Tnnt2 2 0.45 0.84 0.09
78 INT197584 Binding of S100a6 2 0.14 0.81 0.09
79 INT86365 Phosphorylation of TNNT2 1 0.79 0.51 0.09
80 INT168853 Binding of Tnnt2 2 0.19 0.4 0.08
81 INT271359 Negative_regulation of Gene_expression of TNNT2 1 0.07 0.67 0.08
82 INT200595 Regulation of Gene_expression of TNNT2 1 0.24 0.95 0.08
83 INT271364 Positive_regulation of Gene_expression of TNNT2 1 0.09 0.37 0.07
84 INT311813 Binding of S100A6 1 0.14 0.13 0.07
85 INT238471 Negative_regulation of TNNT2 2 0.41 0.77 0.05
86 INT104302 Localization of Tnnt2 2 0.70 0.52 0.04
87 INT183436 Positive_regulation of Localization of Tnnt2 1 0.30 0.45 0.04
88 INT293673 Transcription of S100A6 1 0.38 0.15 0.03
89 INT337400 Negative_regulation of Localization of TNNT1 1 0.42 0.07 0.03
90 INT197866 Binding of S100a6 2 0.41 0 0
91 INT255134 Positive_regulation of Localization of Tnnt2 1 0.44 0.15 0
92 INT197879 Positive_regulation of Binding of S100a6 1 0.42 0 0
93 INT283886 Positive_regulation of Positive_regulation of CALD1 1 0.18 0 0
94 INT287846 Positive_regulation of Phosphorylation of Tnnt2 1 0.25 0 0
95 INT283883 Positive_regulation of Gene_expression of CALD1 1 0.28 0 0
96 INT77428 Negative_regulation of Positive_regulation of S100A6 1 0.15 0 0
97 INT283897 Positive_regulation of Phosphorylation of CALD1 1 0.32 0.32 0
98 INT283890 Phosphorylation of CALD1 1 0.37 1.95 0
99 INT327450 Negative_regulation of Gene_expression of S100A6 1 0.12 0.19 0
100 INT255106 Positive_regulation of Binding of Tnnt2 1 0.44 0.17 0
101 INT82588 Regulation of Gene_expression of S100A6 1 0.44 0.05 0
102 INT134636 Negative_regulation of Tnnt3 1 0.03 0.19 0
103 INT197884 Transcription of S100a6 1 0.45 0 0
104 INT293674 Positive_regulation of Transcription of S100A6 1 0.28 0.15 0
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