GO:0005524

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Name ATP binding
Categary Function
Go Slim No
Go Link GO:0005524
Unique Molecular Interactions 9731
Total Molecular Interactions 12652
Total Single Events 101274
Pain Genes Associated 947

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for ATP binding. They are ordered first by their pain relevance and then by number of times they were reported for ATP binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36
2 INT166591 Binding of CALCA and DCLK3 4 0.30 0.69 12.18
3 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25
4 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
5 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26
6 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33
7 INT259228 Binding of Oprm1 and Glul 1 0.00 0.08 7.22
8 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
9 INT251170 Clu Positive_regulation of Trpv1 1 0.28 2.61 6.49
10 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25
11 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1
12 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 0.74 4.31 6.1
13 INT169218 Binding of EGFR and Coc 1 0.06 2.8 5.85
14 INT227157 Binding of PEBP1 and Gpm6a 1 0.00 1.28 5.52
15 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23
16 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
17 INT166590 Binding of RAMP1 and DCLK3 2 0.37 0.39 4.8
18 INT44716 Binding of ABL2 and PDYN 2 0.40 0.66 4.77
19 INT164362 Binding of NLRP1 and VTA1 1 0.15 2.37 4.67
20 INT351352 Binding of Trpv1 and Lpar1 1 0.21 5.86 4.62
21 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
22 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
23 INT180774 Gdnf Positive_regulation of Trpv1 1 0.33 2.43 4.37
24 INT111758 Binding of Drd2 and Insrr 1 0.01 0.94 4.33
25 INT7022 Drd1a Positive_regulation of Npr1 6 0.05 0.26 4.32
26 INT259209 Binding of Glul and Flna 1 0.03 0 4.2
27 INT161109 Avp Positive_regulation of Chkb 1 0.12 0.18 4.19
28 INT138961 Dbi Positive_regulation of Chkb 1 0.00 3.05 3.99
29 INT32911 Binding of Insrr and Rbm39 2 0.00 0 3.95
30 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92
31 INT130625 Prkcg Regulation of Prkaca 1 0.23 1.32 3.87
32 INT143946 Binding of Pebp1 and Mastl 1 0.00 2.04 3.82
33 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79
34 INT136525 Binding of Prokr1 and Trpv1 1 0.39 2.9 3.76
35 INT141254 Ngf Regulation of Transcription of Trpv1 1 0.53 1.37 3.74
36 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63
37 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
38 INT158770 Binding of Trpv1 and Trpa1 5 0.34 2.07 3.5
39 INT195931 Binding of OPRM1 and Trpv1 1 0.07 0.87 3.43
40 INT73071 Binding of Cpe and Insrr 3 0.01 0.33 3.38
41 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
42 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34
43 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33
44 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
45 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
46 INT276676 Prkcg Regulation of Nav1 1 0.30 0.82 3.29
47 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
48 INT7193 Abl2 Positive_regulation of Ctsb 1 0.21 0 3.21
49 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
50 INT85042 Binding of CCT6A and MAX 1 0.00 0 3.13
51 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11
52 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11
53 INT158752 Binding of TRPV1 and Rvm 1 0.05 1.6 3.1
54 INT158751 Binding of TRPV1 and Pag1 1 0.03 1.59 3.08
55 INT276679 Prkcg Positive_regulation of Positive_regulation of Nkx1-1 1 0.07 0.94 3.08
56 INT122776 Gdnf Positive_regulation of Gene_expression of Trpv1 2 0.67 2.13 3.06
57 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
58 INT111757 Positive_regulation of Binding of Drd2 and Insrr 1 0.02 0.64 2.89
59 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
60 INT140014 Avp Negative_regulation of Chkb 1 0.04 1.58 2.86
61 INT298456 Prkaca Positive_regulation of Phosphorylation of Adarb1 1 0.00 1.86 2.85
62 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84
63 INT351349 Prkcg Positive_regulation of Binding of Lpar1 1 0.15 2 2.82
64 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
65 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
66 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73
67 INT226118 Ghrl Regulation of Prkag1 1 0.08 0.72 2.72
68 INT220061 Binding of TRPV1 and TRPA1 1 0.15 1.7 2.69
69 INT182564 Binding of Ptger2 and Trpv1 1 0.18 1.77 2.67
70 INT92738 Binding of Ephb1 and Tcas1 1 0.00 0.43 2.67
71 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64
72 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63
73 INT223866 Ltp Positive_regulation of Positive_regulation of Mapk1 2 0.46 0.75 2.61
74 INT121742 Prkcg Positive_regulation of Ephb1 3 0.49 0.99 2.6
75 INT67663 Ins1 Positive_regulation of Ntrk2 1 0.00 0.19 2.59
76 INT210696 Trpv1 Regulation of Slc12a2 1 0.25 1.97 2.58
77 INT128044 Bdnf Positive_regulation of Ephb1 2 0.31 1.89 2.57
78 INT111787 Cck Regulation of Gene_expression of Npr1 1 0.22 1.68 2.57
79 INT107322 Positive_regulation of TRPV1 Positive_regulation of Localization of IL8 3 0.13 1.64 2.5
80 INT92182 Mir702 Negative_regulation of Adk 1 0.07 1.29 2.47
81 INT113715 Msh3 Positive_regulation of tf 1 0.11 0 2.47
82 INT147659 Prkce Positive_regulation of TRPV1 1 0.04 1.42 2.43
83 INT122775 Gdnf Regulation of Gene_expression of Trpv1 4 0.59 2.72 2.42
84 INT103332 Ngf Regulation of Gene_expression of TRPV1 3 0.09 2.6 2.4
85 INT136129 Calca Positive_regulation of ATP8A2 1 0.38 0.89 2.4
86 INT284088 Binding of BDNF and NTRK2 5 0.41 3.4 2.37
87 INT121746 Prkaca Positive_regulation of Ephb1 2 0.23 0.92 2.35
88 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
89 INT107165 Binding of Gabrg1 and Trpv1 2 0.01 0.16 2.34
90 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
91 INT139723 PROC Positive_regulation of MAPK8 1 0.01 2.98 2.33
92 INT314205 Ngf Positive_regulation of Phosphorylation of Mapk14 1 0.43 1.24 2.3
93 INT152900 TRPV1 Regulation of Gene_expression of CALCA 1 0.69 0.73 2.29
94 INT152901 TRPV1 Regulation of Localization of CALCA 1 0.44 0.73 2.29
95 INT103548 Binding of TRPV1 and TRPV3 3 0.37 1.82 2.28
96 INT106558 Binding of Ntrk2 and Ntrk3 3 0.52 2.51 2.28
97 INT156623 Umod Regulation of Phosphorylation of Ephb1 1 0.05 0.33 2.27
98 INT228454 Ngf Positive_regulation of Phosphorylation of Trpv1 1 0.39 2.97 2.26
99 INT251164 Binding of Clu and Trpv1 1 0.19 0.44 2.23
100 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21
101 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
102 INT146930 CAP1 Regulation of ABCB1 1 0.29 0.3 2.19
103 INT334136 Binding of IFNA1 and Acsm3 1 0.01 4.52 2.19
104 INT140659 Phax Positive_regulation of Trpv1 3 0.49 0.68 2.18
105 INT135035 Binding of Hk1 and Tac1 1 0.35 0.18 2.14
106 INT212301 NGF Regulation of Gene_expression of TRPV1 1 0.23 2.37 2.13
107 INT344386 Efnb1 Positive_regulation of Phosphorylation of Ephb2 1 0.15 2.85 2.13
108 INT273120 NOVA2 Regulation of Gene_expression of MET 1 0.23 1.17 2.11
109 INT122660 Binding of CACNA1A and DNAH8 2 0.28 2.68 2.08
110 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
111 INT63919 Binding of Cck and Insrr 1 0.01 0 2.08
112 INT63918 Binding of Cck and Ripk2 1 0.28 0 2.07
113 INT190524 Ros1 Positive_regulation of Nfkb1 3 0.02 4.24 2.06
114 INT281084 Prkaca Positive_regulation of Mapk1 2 0.25 0 2.06
115 INT161190 CRX Regulation of Gene_expression of Ntrk2 1 0.04 3.05 2.06
116 INT161187 NMS Regulation of Gene_expression of Ntrk2 1 0.43 3.05 2.06
117 INT33756 Akr1d1 Positive_regulation of Npr1 3 0.01 0 2.05
118 INT167530 Phax Regulation of Gene_expression of Trpv1 1 0.16 0.86 2.05
119 INT121216 Prkca Regulation of Positive_regulation of Oprd1 1 0.02 0.32 2.02
120 INT144115 Positive_regulation of Grm5 Positive_regulation of Prkcg 1 0.41 0 2.01
121 INT124133 Camk2a Regulation of Phosphorylation of Creb1 1 0.46 0 2
122 INT21261 Penk Negative_regulation of Npr1 1 0.02 0 2
123 INT213973 Binding of Pax3 and Mthfd1 1 0.00 0.16 1.99
124 INT213968 Binding of Calca and Mthfd1 1 0.05 0.16 1.99
125 INT137917 Oprm1 Positive_regulation of Kdr 1 0.43 0 1.98
126 INT317540 Camk2a Negative_regulation of Oprm1 1 0.19 0 1.98
127 INT73072 Negative_regulation of Binding of Cpe and Insrr 1 0.00 0 1.94
128 INT153533 NMS Regulation of Gene_expression of Ephb1 1 0.48 3.96 1.93
129 INT104855 Prkaca Regulation of TRPV1 3 0.06 1.52 1.92
130 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
131 INT262558 Phax Positive_regulation of Trpv1 1 0.01 1.26 1.92
132 INT83418 Binding of OPRL1 and Ntrk1 1 0.02 0 1.91
133 INT93293 Ngf Regulation of Trpv1 2 0.28 0.71 1.9
134 INT112514 Binding of Prkaca and Trib3 1 0.03 1.18 1.9
135 INT186435 Prkcg Regulation of Creb1 1 0.44 0.45 1.9
136 INT186432 Prkaca Regulation of Creb1 1 0.14 0.45 1.9
137 INT161079 Mcs18 Negative_regulation of Trpv1 1 0.40 0.82 1.9
138 INT169570 Binding of ROS1 and TRPV1 3 0.33 3.07 1.89
139 INT95405 Trib3 Positive_regulation of Phosphorylation of Ephb1 3 0.08 1.33 1.89
140 INT151965 SORBS1 Positive_regulation of TRPV1 1 0.18 0 1.89
141 INT166945 Ngf Positive_regulation of Trpv1 1 0.01 0.47 1.88
142 INT338691 Binding of Trpv1 and Aff3 1 0.24 1.21 1.88
143 INT135582 Prok2 Positive_regulation of Localization of Prkce 1 0.06 1.02 1.87
144 INT112517 Binding of Ephb1 and Prkaca 3 0.18 0.58 1.85
145 INT349588 Aap Positive_regulation of Gene_expression of Ros1 1 0.06 0.73 1.85
146 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
147 INT314210 Ngf Regulation of Phosphorylation of Mapk14 1 0.34 0.85 1.84
148 INT169468 Binding of Egfr and Spink3 1 0.37 3.73 1.83
149 INT276669 Negative_regulation of Prkcg Regulation of Nav1 1 0.21 0.68 1.82
150 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
151 INT7023 Negative_regulation of Drd1a Positive_regulation of Npr1 2 0.05 0.1 1.81
152 INT99138 Coq10a Regulation of Insrr 1 0.01 0.73 1.81
153 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
154 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
155 INT162992 Binding of Ephb1 and Ppm1e 1 0.03 0.25 1.77
156 INT23392 Gal Regulation of Trpv1 1 0.05 0.33 1.77
157 INT104709 Msh3 Positive_regulation of Rbm39 1 0.01 0.07 1.76
158 INT276863 Gpr65 Regulation of Trpv1 1 0.25 1.78 1.75
159 INT168715 Mapk8 Negative_regulation of Oprk1 1 0.18 0.26 1.75
160 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75
161 INT168716 Mapk8 Negative_regulation of Insrr 1 0.01 0.25 1.75
162 INT167765 Prkca Positive_regulation of Sigmar1 1 0.41 0.63 1.74
163 INT165183 Ifnb1 Positive_regulation of P2rx4 1 0.04 1.73 1.73
164 INT182565 Ptger2 Regulation of Trpv1 1 0.25 1.34 1.73
165 INT346217 Braf Positive_regulation of Phosphorylation of Map2k1 1 0.22 3.23 1.72
166 INT282398 Binding of Mefv and Nlrp3 1 0.40 6.8 1.72
167 INT175986 Ros1 Positive_regulation of Gtf3a 2 0.01 4.75 1.71
168 INT186433 Trib3 Regulation of Phosphorylation of Creb1 1 0.03 0.32 1.71
169 INT68709 Positive_regulation of Crh Regulation of Npr1 1 0.03 0 1.71
170 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
171 INT134363 Prkcg Regulation of ADCY2 1 0.00 0.14 1.7
172 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
173 INT68710 Crh Regulation of Npr1 1 0.03 0 1.7
174 INT108385 Binding of Crygs and Ntrk1 1 0.01 0 1.67
175 INT276672 Binding of Prkcg and Nav1 1 0.16 0.18 1.67
176 INT139433 Binding of Prkaca and Prkca 1 0.37 0.13 1.67
177 INT108066 Binding of NTRK1 and Ngf 3 0.33 2.56 1.66
178 INT249483 Binding of Ephb1 and Efnb2 1 0.02 2.35 1.66
179 INT276680 Binding of Prkcg and Nkx1-1 1 0.05 0.18 1.66
180 INT122428 Binding of Ighm and Prkci 1 0.00 0 1.66
181 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
182 INT96296 Oprm1 Negative_regulation of Npr1 2 0.05 0.32 1.65
183 INT278223 Binding of NOS3 and ACSM3 1 0.41 6.32 1.65
184 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
185 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63
186 INT114396 Positive_regulation of Vta1 Negative_regulation of Positive_regulation of Nlrp1a 1 0.03 0 1.63
187 INT135516 PRKCA Negative_regulation of Phosphorylation of OPRM1 1 0.12 0 1.62
188 INT147654 DYT10 Negative_regulation of Positive_regulation of TRPV1 1 0.27 0.93 1.62
189 INT147652 PLCB1 Negative_regulation of Positive_regulation of TRPV1 1 0.27 0.92 1.62
190 INT317184 BMS1 Regulation of Gene_expression of NAV1 1 0.03 1.94 1.62
191 INT90929 Binding of Ap1m1 and Insrr 1 0.01 0.19 1.6
192 INT21570 Binding of Cck and Mapk8 1 0.06 0 1.6
193 INT276670 Binding of Trpv1 and Nkx1-1 1 0.07 0.68 1.6
194 INT195930 OPRM1 Regulation of Prkaca 1 0.01 0 1.59
195 INT33757 Hmmr Positive_regulation of Npr1 1 0.01 0 1.59
196 INT48790 Negative_regulation of Rtcd1 Negative_regulation of Pax3 1 0.02 0 1.59
197 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
198 INT149632 Binding of HK1 and NCOR2 1 0.01 0.13 1.58
199 INT118515 Positive_regulation of PRKCA Positive_regulation of Phosphorylation of TRPV1 1 0.27 0.56 1.58
200 INT131575 Grin1 Negative_regulation of Positive_regulation of Ephb1 1 0.28 0.31 1.58

Single Events

The table below shows the top 100 pain related interactions that have been reported for ATP binding. They are ordered first by their pain relevance and then by number of times they were reported in ATP binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59
2 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42
3 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42
4 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81
5 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41
6 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14
7 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05
8 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59
9 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94
10 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47
11 INT63934 Phosphorylation of Ephb1 377 0.82 150.52 188.66
12 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61
13 INT1303 Negative_regulation of Npr1 278 0.55 35.1 156.78
14 INT60126 Regulation of Trpv1 186 0.62 85.53 133.4
15 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91
16 INT4259 Positive_regulation of Npr1 262 0.70 49.37 123.11
17 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75
18 INT48923 Gene_expression of Ephb1 211 0.77 106.23 109.9
19 INT47243 Gene_expression of Prkcg 195 0.78 58.05 108.44
20 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83
21 INT89054 Positive_regulation of Gene_expression of Trpv1 156 0.70 90.78 102.03
22 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46
23 INT52651 Positive_regulation of Prkaca 136 0.67 40.82 99.16
24 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51
25 INT38731 Localization of Trpv1 138 0.81 52.73 90.49
26 INT6585 Positive_regulation of Insrr 110 0.52 40.67 89.9
27 INT12763 Phosphorylation of Prkcg 167 0.82 38.91 89.63
28 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27
29 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79
30 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66
31 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01
32 INT15898 Positive_regulation of Prkaca 199 0.70 50.89 87.54
33 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
34 INT4830 Binding of Trpv1 158 0.48 45.11 84.2
35 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46
36 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5
37 INT10534 Positive_regulation of Trib3 209 0.60 78.75 81.48
38 INT99070 Gene_expression of Mapk14 147 0.78 103.99 79.59
39 INT12476 Negative_regulation of TRPV1 124 0.59 47.95 77.98
40 INT9382 Regulation of TRPV1 149 0.62 53.99 77.46
41 INT133211 Gene_expression of Runx1 169 0.77 83.4 76.16
42 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7
43 INT16654 Gene_expression of Insrr 138 0.46 58.96 75.68
44 INT98621 Regulation of Trpv1 121 0.62 79.24 75.23
45 INT12536 Localization of Prkcg 101 0.80 36.37 73.81
46 INT63936 Positive_regulation of Phosphorylation of Ephb1 131 0.70 49.38 73.16
47 INT4153 Binding of Insrr 109 0.40 17.99 72.15
48 INT49111 Negative_regulation of Prkaca 102 0.59 27.44 71.77
49 INT6490 Negative_regulation of ADCY1 145 0.58 26.25 70.96
50 INT53964 Negative_regulation of Prkaca 131 0.58 38.76 69.52
51 INT87686 Positive_regulation of Gene_expression of Trpv1 101 0.70 72.41 69.15
52 INT39777 Regulation of Prkcg 90 0.62 31.52 68.17
53 INT1603 Negative_regulation of Rtcd1 131 0.51 29.99 66.66
54 INT1599 Positive_regulation of ADCY1 146 0.67 30.05 64.9
55 INT96622 Localization of Trpv1 110 0.81 59.82 63.25
56 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28
57 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72
58 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
59 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98
60 INT62960 Gene_expression of P2rx2 149 0.77 58.31 59.16
61 INT83602 Positive_regulation of Gene_expression of TRPV1 114 0.70 51.19 56.35
62 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97
63 INT31186 Negative_regulation of Insrr 81 0.37 24.91 55.94
64 INT49436 Binding of TRPV1 145 0.48 38.35 55.08
65 INT119528 Positive_regulation of Camk2a 135 0.70 26.13 54.7
66 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
67 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
68 INT84495 Positive_regulation of Positive_regulation of Ephb1 85 0.70 46.12 54.11
69 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32
70 INT48920 Negative_regulation of Ephb1 107 0.57 43.6 51.02
71 INT1232 Positive_regulation of Pdpk1 78 0.42 24.33 50.17
72 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
73 INT49520 Gene_expression of P2rx3 121 0.78 61.15 49.24
74 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
75 INT12471 Regulation of Insrr 52 0.35 17.8 48.31
76 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
77 INT48718 Positive_regulation of PRKCA 109 0.69 36.16 46.49
78 INT9383 Localization of TRPV1 98 0.81 33.23 46.24
79 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17
80 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42
81 INT98498 Binding of Trpv1 75 0.48 33.67 44.4
82 INT66383 Phosphorylation of Prkaca 143 0.80 30.85 43.38
83 INT27798 Gene_expression of Ntrk2 111 0.78 56.08 42.68
84 INT48929 Regulation of Ephb1 71 0.62 24.42 42.11
85 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04
86 INT18992 Negative_regulation of Pdpk1 53 0.42 19.02 40.95
87 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56
88 INT61925 Negative_regulation of Adk 53 0.59 22.46 40.38
89 INT92437 Positive_regulation of Phosphorylation of Mapk1 113 0.70 32.19 40.29
90 INT114751 Gene_expression of Mapk1 137 0.76 60.14 39.98
91 INT102902 Gene_expression of Ntrk2 152 0.78 81.52 39.43
92 INT102611 Negative_regulation of Positive_regulation of Mapk1 74 0.58 35.57 39.37
93 INT58062 Negative_regulation of Gene_expression of Trpv1 66 0.59 22.34 38.02
94 INT115649 Gene_expression of Camk2a 95 0.78 33.22 38
95 INT48933 Gene_expression of Mapk3 93 0.75 44.39 37.92
96 INT80075 Regulation of Gene_expression of Trpv1 55 0.62 32.42 36.88
97 INT97702 Positive_regulation of Phosphorylation of Mapk14 69 0.69 49.21 36.81
98 INT80690 Positive_regulation of MAPK8 223 0.68 125.63 36.75
99 INT48959 Positive_regulation of Positive_regulation of Prkcg 52 0.70 16.47 36.49
100 INT64436 Gene_expression of P2rx1 93 0.78 32.69 36.12
101 INT84260 Positive_regulation of Mapk8 124 0.69 72.84 35.98
102 INT76531 Transcription of Trpv1 62 0.72 23.69 34.77
103 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
104 INT12765 Positive_regulation of Phosphorylation of Prkcg 59 0.66 20.16 34.67
105 INT12161 Positive_regulation of P2rx2 70 0.69 34.22 34.4
106 INT96624 Positive_regulation of Positive_regulation of Trpv1 62 0.70 20.5 34.28
107 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08
108 INT109434 Phosphorylation of Mapk1 110 0.82 61.64 34.05
109 INT48924 Positive_regulation of Mapk3 107 0.67 50.53 34.05
110 INT12537 Positive_regulation of Localization of Prkcg 36 0.70 14.57 33.81
111 INT95734 Phosphorylation of Mapk8 108 0.82 49.92 33.52
112 INT63933 Negative_regulation of Positive_regulation of Ephb1 53 0.58 22.83 33.43
113 INT114729 Phosphorylation of Camk2a 110 0.82 15.49 33.19
114 INT63935 Positive_regulation of Gene_expression of Ephb1 52 0.61 24.3 33.05
115 INT48925 Gene_expression of Mapk1 95 0.74 42.21 32.91
116 INT51698 Positive_regulation of Gene_expression of Prkcg 44 0.68 14.02 32.9
117 INT89055 Phosphorylation of Prkaca 60 0.61 13.41 32.49
118 INT14823 Gene_expression of MET 103 0.75 51.92 32.48
119 INT1495 Positive_regulation of Rtcd1 91 0.54 22.93 32.43
120 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2
121 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
122 INT5069 Negative_regulation of Mthfs 69 0.57 22.54 31.36
123 INT117112 Negative_regulation of Mapk1 87 0.56 40.34 31.18
124 INT64164 Regulation of Prkca 34 0.62 10.44 30.99
125 INT70776 Positive_regulation of P2rx1 62 0.62 32.55 30.75
126 INT8691 Localization of Insr 85 0.80 9.27 30.32
127 INT72375 Phosphorylation of Mapk3 87 0.80 43.66 30.27
128 INT6762 Binding of Srms 56 0.31 6.62 30.27
129 INT110020 Gene_expression of Mapk14 142 0.77 72.33 30.08
130 INT9133 Negative_regulation of Positive_regulation of Prkcg 37 0.59 10.95 30.06
131 INT5300 Regulation of Insr 54 0.60 11.33 29.26
132 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
133 INT84494 Negative_regulation of Phosphorylation of Ephb1 44 0.59 22.34 28.68
134 INT52712 Negative_regulation of PRKCA 64 0.57 23.11 28.43
135 INT5298 Negative_regulation of MTHFS 70 0.57 27.07 28.11
136 INT66381 Regulation of Prkaca 40 0.62 13.38 27.96
137 INT83708 Negative_regulation of MAPK1 156 0.57 84.93 27.85
138 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
139 INT133876 Positive_regulation of Gene_expression of Ros1 141 0.32 75.55 27.45
140 INT123035 Gene_expression of Ephb1 38 0.78 28.84 27.32
141 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21
142 INT21900 Gene_expression of Mthfd1 150 0.75 69.47 27.03
143 INT12681 Regulation of Trib3 76 0.53 23.92 26.58
144 INT95481 Regulation of Gene_expression of TRPV1 48 0.62 29.3 26.28
145 INT95788 Positive_regulation of Positive_regulation of Mapk1 83 0.69 24.75 25.84
146 INT5426 Negative_regulation of RTCA 58 0.51 12.34 25.74
147 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69
148 INT86789 Gene_expression of P2rx4 46 0.77 30.66 25.68
149 INT112036 Phosphorylation of Trpv1 51 0.82 18.59 25.6
150 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58
151 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
152 INT79979 Gene_expression of Ret 94 0.75 19.21 25.51
153 INT103320 Positive_regulation of Positive_regulation of Trpv1 44 0.70 27.73 25.28
154 INT68758 Positive_regulation of Ros1 125 0.46 82.72 25.27
155 INT9781 Binding of INSRR 64 0.31 19.1 25.2
156 INT92105 Transcription of Trpv1 47 0.71 27.47 25.01
157 INT106272 Positive_regulation of Positive_regulation of Mapk14 39 0.70 32.08 24.71
158 INT96904 Regulation of Prkaca 33 0.44 10.86 24.51
159 INT9377 Positive_regulation of Positive_regulation of TRPV1 43 0.70 15.81 24.47
160 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
161 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
162 INT9155 Gene_expression of Glul 60 0.77 17.97 23.95
163 INT37889 Gene_expression of P2ry2 75 0.65 26.01 23.8
164 INT123386 Negative_regulation of Camk2a 48 0.58 12.57 23.78
165 INT71781 Phosphorylation of MAPK3 62 0.80 27.73 23.73
166 INT86534 Positive_regulation of MAPK14 81 0.62 57.81 23.62
167 INT125190 Regulation of Gene_expression of Trpv1 38 0.62 32.57 23.2
168 INT99069 Positive_regulation of Gene_expression of Mapk14 42 0.53 29.84 23.16
169 INT90300 Gene_expression of Abcb1a 56 0.78 11.05 22.89
170 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83
171 INT87607 Positive_regulation of Prkcc 25 0.69 6.06 22.78
172 INT69322 Negative_regulation of MAPK14 70 0.54 42.92 22.71
173 INT106720 Positive_regulation of Adcy1 30 0.50 22.05 22.68
174 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67
175 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
176 INT15326 Phosphorylation of Trib3 83 0.55 30.96 22.27
177 INT48312 Gene_expression of NTRK1 72 0.78 38.21 22.24
178 INT1558 Positive_regulation of Dnahc8 30 0.69 5.78 22.19
179 INT89056 Phosphorylation of Trpv1 46 0.82 13.52 22.16
180 INT2911 Positive_regulation of Glul 36 0.70 11.09 22.07
181 INT103842 Gene_expression of Cftr 53 0.78 59.59 21.82
182 INT171924 Gene_expression of MAPK14 60 0.65 54.38 21.68
183 INT10536 Gene_expression of Trib3 67 0.66 27.08 21.58
184 INT121872 Gene_expression of Camk4 156 0.78 70.47 21.39
185 INT112427 Positive_regulation of P2rx4 27 0.68 26.29 21.31
186 INT99068 Gene_expression of Mapk8 62 0.78 33.57 21.25
187 INT117527 Binding of Prkca 25 0.48 6.43 21.05
188 INT1561 Negative_regulation of Dnahc8 59 0.59 18.12 20.99
189 INT72060 Positive_regulation of Gene_expression of Ros1 127 0.41 76.76 20.91
190 INT99237 Gene_expression of Ntrk3 84 0.77 38.68 20.77
191 INT89805 Gene_expression of Prkaca 45 0.77 11.03 20.77
192 INT56769 Gene_expression of Ntrk1 36 0.77 15.79 20.75
193 INT50778 Gene_expression of Adrbk1 24 0.77 11.61 20.73
194 INT54708 Gene_expression of Adrbk1 22 0.75 1.06 20.62
195 INT79805 Phosphorylation of PRKCA 57 0.81 23.33 20.41
196 INT112930 Negative_regulation of Adrbk1 17 0.58 15.04 20.41
197 INT48769 Regulation of Pdpk1 20 0.35 9.78 20.36
198 INT1756 Negative_regulation of DNAH8 105 0.59 42.73 20.24
199 INT7017 Regulation of Npr1 45 0.52 3.38 20.05
200 INT125411 Negative_regulation of Phosphorylation of Mapk14 31 0.57 18.55 19.98
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