GO:0005525

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Name GTP binding
Categary Function
Go Slim No
Go Link GO:0005525
Unique Molecular Interactions 1163
Total Molecular Interactions 1599
Total Single Events 11880
Pain Genes Associated 176

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for GTP binding. They are ordered first by their pain relevance and then by number of times they were reported for GTP binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT324068 Binding of GCH1 and SNRNP70 1 0.01 28.19 40.6
2 INT269444 Binding of RAB5A and HHIP 1 0.04 0 5.79
3 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
4 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
5 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
6 INT7022 Drd1a Positive_regulation of Npr1 6 0.05 0.26 4.32
7 INT103724 Oprd1 Positive_regulation of Gtpbp4 3 0.30 0.91 4.18
8 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
9 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34
10 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33
11 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
12 INT264929 Binding of Cnr1 and Gnaz 1 0.18 1.71 2.89
13 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 1 0.06 0.5 2.6
14 INT111787 Cck Regulation of Gene_expression of Npr1 1 0.22 1.68 2.57
15 INT96465 Pnoc Positive_regulation of GEM 1 0.01 0.74 2.39
16 INT350148 Binding of IL12A and ERAL1 1 0.21 8.23 2.26
17 INT133946 Binding of DNM2 and OPRK1 1 0.11 0 2.1
18 INT64750 Binding of Oprm1 and Pck1 2 0.41 0.51 2.07
19 INT33756 Akr1d1 Positive_regulation of Npr1 3 0.01 0 2.05
20 INT21261 Penk Negative_regulation of Npr1 1 0.02 0 2
21 INT13940 DNM2 Regulation of Localization of CGA 1 0.11 0 1.86
22 INT7023 Negative_regulation of Drd1a Positive_regulation of Npr1 2 0.05 0.1 1.81
23 INT68709 Positive_regulation of Crh Regulation of Npr1 1 0.03 0 1.71
24 INT68710 Crh Regulation of Npr1 1 0.03 0 1.7
25 INT80199 Ngf Regulation of Transcription of Rab38 1 0.01 1.48 1.68
26 INT324067 Regulation of Binding of GCH1 and SNRNP70 1 0.01 0.95 1.67
27 INT96296 Oprm1 Negative_regulation of Npr1 2 0.05 0.32 1.65
28 INT236491 GCH1 Regulation of Pain1 1 0.01 0.89 1.65
29 INT103725 Negative_regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.17 0.38 1.65
30 INT103726 Regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.10 0.38 1.64
31 INT317184 BMS1 Regulation of Gene_expression of NAV1 1 0.03 1.94 1.62
32 INT247281 GLC1N Negative_regulation of HRAS 1 0.02 1.98 1.62
33 INT33757 Hmmr Positive_regulation of Npr1 1 0.01 0 1.59
34 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
35 INT284785 Gch1 Regulation of Bh4p 1 0.00 1.48 1.54
36 INT351366 LPA Positive_regulation of Rab38 1 0.00 0.95 1.53
37 INT240057 Binding of RHOB and NME8 1 0.41 4.11 1.5
38 INT291583 GUCY2C Regulation of Pde5a 1 0.00 1.12 1.45
39 INT21425 Binding of Pomc and Gtpbp4 1 0.01 0.1 1.45
40 INT133933 Binding of DNM2 and TP53INP2 1 0.00 0 1.38
41 INT6466 Binding of Npr1 and Oprd1 1 0.01 0 1.37
42 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36
43 INT122659 Binding of CACNA1A and SAR1B 1 0.06 1.38 1.35
44 INT135830 Gch1 Regulation of Nos2 1 0.65 0 1.29
45 INT63407 Binding of Oprl1 and Pck1 1 0.40 0 1.29
46 INT115985 Cpe Positive_regulation of Binding of Gnas 1 0.00 0.17 1.28
47 INT64749 Negative_regulation of Binding of Oprm1 and Pck1 1 0.47 0.21 1.27
48 INT143620 Ltp Positive_regulation of Npr1 1 0.01 0.16 1.26
49 INT121464 Negative_regulation of Oprm1 Positive_regulation of Dnm2 1 0.34 0 1.26
50 INT121465 Binding of Dnm2 and Oprm1 1 0.23 0 1.24
51 INT42554 Oprl1 Regulation of Npr1 2 0.06 0 1.22
52 INT124874 Gnat3 Positive_regulation of Localization of Calca 2 0.08 0.75 1.2
53 INT21424 Binding of Penk and Gtpbp4 1 0.02 0.16 1.2
54 INT228681 Fkbp4 Negative_regulation of Trib3 1 0.00 0.57 1.2
55 INT116730 Rac1 Regulation of Localization of Calca 1 0.13 1.32 1.19
56 INT13205 Oprd1 Negative_regulation of Npr1 2 0.01 0 1.16
57 INT264930 Gnaz Positive_regulation of Negative_regulation of Cnr1 1 0.20 0 1.14
58 INT13204 Binding of Npr1 and Akr1d1 1 0.00 0 1.14
59 INT117504 OPA1 Positive_regulation of CPP 1 0.09 1.09 1.13
60 INT7024 Regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.07 1.13
61 INT130627 Gnas Regulation of Prkaca 1 0.00 0 1.13
62 INT264931 Binding of Gnaz and Hrh1 1 0.01 0.83 1.12
63 INT207437 Binding of PLA2G7 and ERAL1 1 0.14 3.64 1.11
64 INT64259 Binding of Gtpbp4 and Ptprg 1 0.06 0 1.1
65 INT308173 Binding of DRG1 and Tnfrsf1b 1 0.01 1.64 1.1
66 INT127133 Positive_regulation of OPRM1 Positive_regulation of Protein_catabolism of SUCLG2 1 0.20 0.2 1.1
67 INT230019 Binding of HLA-B and ERAL1 1 0.00 2.23 1.1
68 INT269443 Positive_regulation of Binding of RAB5A and HHIP 1 0.04 0 1.06
69 INT18828 DNM2 Positive_regulation of Localization of LTB4R 1 0.01 0.07 1.06
70 INT118859 GNA14 Positive_regulation of STAT3 1 0.01 0.38 1.03
71 INT33142 Pck1 Positive_regulation of Npr1 4 0.01 0.5 1.02
72 INT224856 Binding of Bdnf and Eef2 1 0.14 0 1.02
73 INT157142 OPA1 Positive_regulation of Gene_expression of Camk2a 1 0.02 0.3 1.02
74 INT13502 Penk Positive_regulation of Npr1 1 0.02 0.19 1.01
75 INT144661 Dnm1 Negative_regulation of Binding of Hbegf 1 0.24 0 1.01
76 INT13503 Regulation of Penk Positive_regulation of Npr1 1 0.02 0.19 1.01
77 INT7025 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.08 1.01
78 INT42555 Oprl1 Negative_regulation of Npr1 1 0.02 0 0.99
79 INT61637 Binding of P2ry2 and Gtpbp4 1 0.02 0.1 0.99
80 INT267886 Arl10 Positive_regulation of Insrr 1 0.00 0.07 0.98
81 INT166790 HRAS Negative_regulation of Gene_expression of PTGER1 1 0.01 1.46 0.95
82 INT73466 PTPLA Positive_regulation of Transcription of Hras1 1 0.21 0.98 0.95
83 INT266659 Binding of MMP9 and MOCS1 1 0.01 1.71 0.94
84 INT264926 Binding of Gnaz and Pag1 1 0.08 0.19 0.94
85 INT153685 Binding of Bcl2l11 and Gtpbp4 1 0.08 0.76 0.93
86 INT54200 Gnai1 Negative_regulation of Pag1 1 0.05 0.18 0.9
87 INT54197 Binding of Gnai1 and Pag1 1 0.04 0.18 0.9
88 INT53152 Rac1 Regulation of Scg2 1 0.03 0 0.9
89 INT121702 HRAS Negative_regulation of Positive_regulation of MMP1 1 0.06 0.2 0.9
90 INT121701 HRAS Negative_regulation of MMP1 1 0.06 0.2 0.89
91 INT121704 HRAS Negative_regulation of MMP3 1 0.06 0.19 0.89
92 INT53155 Rac1 Positive_regulation of Gene_expression of Calca 1 0.06 0 0.89
93 INT301079 Binding of GNAT1 and INPP5E 1 0.00 0.59 0.89
94 INT121699 HRAS Negative_regulation of Gene_expression of MMP1 1 0.06 0.19 0.88
95 INT151630 Il1rn Negative_regulation of Dock9 1 0.03 1.33 0.88
96 INT96010 KNG1 Positive_regulation of Binding of MTG1 1 0.32 0.15 0.88
97 INT96009 KNG1 Positive_regulation of MTG1 1 0.32 0.15 0.88
98 INT207439 Binding of HCRT and ERAL1 1 0.00 3.06 0.87
99 INT111790 Penk Regulation of Gene_expression of Npr1 1 0.22 0.56 0.86
100 INT124878 Gnat3 Negative_regulation of Gene_expression of FOS 1 0.09 0.16 0.85
101 INT306831 Positive_regulation of Binding of E2F4 and NOLC1 1 0.10 0.46 0.85
102 INT41156 Sst Negative_regulation of Npr1 1 0.05 0 0.84
103 INT306826 Binding of E2F4 and NOLC1 1 0.08 0.41 0.84
104 INT29781 PDYN Negative_regulation of Npr1 1 0.00 0.22 0.84
105 INT74383 Sst Positive_regulation of GEM 1 0.01 0.09 0.82
106 INT269455 Binding of RAB5A and GOPC 1 0.08 0 0.82
107 INT74382 Negative_regulation of Sst Positive_regulation of GEM 1 0.00 0.09 0.82
108 INT124877 Gnat3 Negative_regulation of FOS 1 0.09 0.15 0.82
109 INT124876 Gnat3 Negative_regulation of Positive_regulation of FOS 1 0.09 0.15 0.82
110 INT74384 Regulation of Sst Positive_regulation of GEM 1 0.00 0.09 0.82
111 INT80200 Negative_regulation of Ngf Negative_regulation of Gene_expression of Rab38 1 0.01 0.68 0.8
112 INT114068 Agtr2 Regulation of Gene_expression of Insr 1 0.15 0.95 0.79
113 INT128180 Gna12 Regulation of Regulation of RHOA 1 0.00 0 0.78
114 INT142454 Npff Positive_regulation of Gtpbp4 1 0.56 0 0.78
115 INT142455 Binding of Npff and Gtpbp4 1 0.40 0 0.78
116 INT298457 Binding of Calca and Npr1 1 0.01 0.39 0.77
117 INT81976 Binding of GNA15 and OPRL1 1 0.02 0 0.77
118 INT118854 GNA14 Positive_regulation of Positive_regulation of STAT3 1 0.02 0.31 0.76
119 INT76499 Binding of Insr and Adora2a 1 0.08 0 0.76
120 INT133935 DNM2 Positive_regulation of OPRK1 1 0.11 0 0.76
121 INT21260 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.05 0 0.76
122 INT147619 Npr1 Positive_regulation of Localization of Calca 1 0.03 0 0.75
123 INT111194 Binding of NEUROD1 and Pck1 1 0.39 0 0.75
124 INT57658 ASNA1 Positive_regulation of Npr1 1 0.00 0.15 0.74
125 INT162164 ARF6 Regulation of Positive_regulation of PLD2 1 0.60 0 0.74
126 INT43662 Negative_regulation of Binding of Chrna7 and Rac1 1 0.01 0 0.73
127 INT148909 Binding of GNA13 and TP53INP2 1 0.06 0.31 0.73
128 INT133943 Binding of DNM2 and OPRL1 1 0.00 0 0.73
129 INT290544 Negative_regulation of Crh Positive_regulation of Insr 1 0.01 0.3 0.72
130 INT43663 Binding of Chrna7 and Rac2 1 0.01 0 0.72
131 INT43661 Binding of Chrna7 and Rac1 1 0.01 0 0.72
132 INT162162 ARF6 Regulation of OPRM1 1 0.19 0 0.71
133 INT262574 Gnaq Positive_regulation of Prkca 1 0.00 0.57 0.71
134 INT123869 Binding of GNAS and OPRK1 1 0.00 0.37 0.7
135 INT43647 Binding of Eef1a1 and Man2a2 1 0.16 0.23 0.7
136 INT169603 Nppb Regulation of Npr1 1 0.26 0.95 0.69
137 INT133936 Binding of DNM2 and YY1 1 0.29 0 0.69
138 INT71988 Drd1a Regulation of Npr1 1 0.10 0 0.68
139 INT121966 HRAS Positive_regulation of RAC1 1 0.75 0.41 0.67
140 INT113931 Mors1 Positive_regulation of Gtpbp4 1 0.02 0 0.67
141 INT180961 Binding of MOCS1 and PLAU 1 0.00 0.61 0.67
142 INT264927 Cnr1 Regulation of Gnaz 1 0.23 0.05 0.66
143 INT111555 Negative_regulation of Npr1 Negative_regulation of Positive_regulation of Creb1 1 0.02 0.58 0.66
144 INT118824 OPA1 Positive_regulation of Gene_expression of Nos1 2 0.03 0.24 0.65
145 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
146 INT184193 HRAS Negative_regulation of Gene_expression of IL1B 1 0.00 1.12 0.65
147 INT290549 Gopc Positive_regulation of Positive_regulation of Insr 1 0.01 0.06 0.65
148 INT62849 TUBE1 Positive_regulation of Rmp1 1 0.02 0 0.65
149 INT290545 Crh Positive_regulation of Positive_regulation of Insr 1 0.02 0.06 0.64
150 INT290550 Gopc Positive_regulation of Insr 1 0.01 0.06 0.64
151 INT6464 Sst Regulation of Negative_regulation of Npr1 1 0.01 0 0.64
152 INT290540 Positive_regulation of Crh Positive_regulation of Insr 1 0.02 0.06 0.64
153 INT6463 Oprd1 Regulation of Negative_regulation of Npr1 1 0.01 0 0.63
154 INT6465 Trh Regulation of Negative_regulation of Npr1 1 0.01 0 0.63
155 INT34211 DNM2 Regulation of Localization of Crh 1 0.01 0.09 0.63
156 INT334594 Binding of GNAI1 and MRGPRD 1 0.01 0.19 0.63
157 INT36511 Binding of Htr2a and Eef1a1 1 0.22 0 0.62
158 INT330104 Binding of Sh3rf1 and Rac1 1 0.13 2.41 0.62
159 INT46493 Binding of Insr and Oxt 1 0.14 0 0.62
160 INT330101 Binding of Map3k11 and Rac1 1 0.16 2.43 0.62
161 INT247285 GLC1N Positive_regulation of Gene_expression of HRAS 1 0.02 1.3 0.61
162 INT276217 Pdk1 Positive_regulation of Positive_regulation of Insr 1 0.05 0.1 0.6
163 INT89010 Arc Positive_regulation of Insr 1 0.08 0.86 0.59
164 INT142993 Serpinc1 Positive_regulation of Phosphorylation of RHOA 1 0.05 0.05 0.59
165 INT161387 Binding of PNOC and GTPBP4 1 0.03 1.05 0.59
166 INT321300 Ins1 Negative_regulation of Pck1 1 0.09 0.52 0.59
167 INT89012 DST Positive_regulation of Insr 1 0.01 0.86 0.59
168 INT70468 Binding of HTR1B and MTG1 1 0.40 0 0.56
169 INT41250 Binding of Adra2a and Eef1a1 1 0.06 0.4 0.56
170 INT59635 Binding of Adarb1 and Gnaz 1 0.01 0 0.55
171 INT267890 Arl10 Regulation of Insrr 1 0.00 0.43 0.54
172 INT164971 Binding of Rgs7 and Gnai2 1 0.01 0 0.54
173 INT269449 Positive_regulation of Binding of RAB5A and GOPC 1 0.11 0 0.53
174 INT164970 Binding of Rgs8 and Gnai2 1 0.01 0 0.53
175 INT114070 Agtr2 Positive_regulation of Gene_expression of Insr 1 0.13 0.34 0.52
176 INT97949 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of CDC42 1 0.06 0.72 0.51
177 INT77218 Binding of NFKBIL1 and NKIRAS2 1 0.00 0.27 0.51
178 INT182813 EEF1A2 Negative_regulation of ITGAL 1 0.10 1.53 0.51
179 INT43075 Slc6a14 Regulation of Positive_regulation of Npr1 1 0.01 0 0.51
180 INT43076 Slc6a14 Regulation of Npr1 1 0.01 0 0.51
181 INT33415 KNG1 Positive_regulation of GBP1 1 0.02 0.43 0.51
182 INT7120 Nppb Positive_regulation of Localization of Rab8a 1 0.08 0 0.51
183 INT97953 ST3GAL3 Positive_regulation of CDC42 1 0.09 0.7 0.5
184 INT81004 Htr1a Positive_regulation of Gtpbp4 1 0.20 0 0.5
185 INT243998 Binding of Prkaca and Dnm1 1 0.11 0.24 0.49
186 INT243999 Positive_regulation of Binding of Prkaca and Dnm1 1 0.14 0.24 0.49
187 INT244000 Positive_regulation of Binding of Tfap2a and Dnm1 1 0.04 0.24 0.49
188 INT243997 Binding of Tfap2a and Dnm1 1 0.03 0.24 0.49
189 INT212806 Rngtt Negative_regulation of Gene_expression of Nos2 1 0.03 0.9 0.49
190 INT131508 Gene_expression of Rac1 Positive_regulation of Trpv1 1 0.42 0.21 0.48
191 INT131503 Gene_expression of Rac1 Positive_regulation of Ngf 1 0.38 0.21 0.48
192 INT155881 Binding of CDX2 and KRAS 1 0.40 1.51 0.47
193 INT114065 Akt1 Regulation of Gene_expression of Insr 1 0.13 0.28 0.46
194 INT153658 PRKCA Negative_regulation of GEM 1 0.01 0.22 0.46
195 INT37599 Ace Regulation of Localization of Insr 1 0.18 0 0.46
196 INT55265 Ptgdr Negative_regulation of Npr1 1 0.01 0 0.46
197 INT344709 Niacr1 Positive_regulation of Hdl1 1 0.32 2.74 0.46
198 INT95564 Positive_regulation of HRAS Positive_regulation of IL12A 1 0.03 0.7 0.45
199 INT52679 Positive_regulation of Npr1 Positive_regulation of Positive_regulation of VSX1 1 0.00 0 0.45
200 INT95562 HRAS Positive_regulation of IL12A 1 0.03 0.7 0.45

Single Events

The table below shows the top 100 pain related interactions that have been reported for GTP binding. They are ordered first by their pain relevance and then by number of times they were reported in GTP binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1303 Negative_regulation of Npr1 278 0.55 35.1 156.78
2 INT4259 Positive_regulation of Npr1 262 0.70 49.37 123.11
3 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
4 INT12717 Binding of Pck1 85 0.47 12.49 54.81
5 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
6 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
7 INT9298 Positive_regulation of Gtpbp4 64 0.69 12.29 41.97
8 INT8691 Localization of Insr 85 0.80 9.27 30.32
9 INT19396 Regulation of Rac1 66 0.53 37.41 30.01
10 INT5300 Regulation of Insr 54 0.60 11.33 29.26
11 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33
12 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78
13 INT13108 Binding of MTG1 35 0.47 6.36 20.5
14 INT7017 Regulation of Npr1 45 0.52 3.38 20.05
15 INT4260 Negative_regulation of Positive_regulation of Npr1 29 0.43 4.39 19.57
16 INT6461 Gene_expression of Npr1 35 0.75 10.38 17.58
17 INT150934 Gene_expression of GCH1 17 0.78 14.54 17.53
18 INT9299 Positive_regulation of Positive_regulation of Npr1 32 0.53 6.65 16.72
19 INT7531 Positive_regulation of Eef1a1 29 0.62 8.16 15.41
20 INT23212 Positive_regulation of Rac1 46 0.55 32.85 15.1
21 INT8989 Binding of Npr1 25 0.36 5.52 14.58
22 INT49089 Gene_expression of Rab38 22 0.45 6.79 13.76
23 INT27627 Binding of Rac1 41 0.41 22.88 13.68
24 INT14768 Negative_regulation of Positive_regulation of Insr 16 0.56 5.51 13.59
25 INT21421 Regulation of Gtpbp4 15 0.30 2.7 13.49
26 INT26545 Gene_expression of Hras1 173 0.78 79.54 13.21
27 INT110988 Gene_expression of Insr 58 0.42 42.12 12.18
28 INT146197 Positive_regulation of Rhoa 60 0.68 34.12 12.02
29 INT49087 Positive_regulation of Rab38 20 0.00 8.01 12
30 INT16659 Gene_expression of Eef1a1 34 0.64 6.1 11.85
31 INT204112 Gene_expression of GEM 43 0.75 38.74 11.23
32 INT91357 Regulation of Dnm2 5 0.61 0 11.06
33 INT67915 Negative_regulation of Gtpbp4 18 0.33 6.31 10.17
34 INT139443 Positive_regulation of GCH1 9 0.69 8.2 10.14
35 INT13606 Negative_regulation of Negative_regulation of Npr1 13 0.40 1.21 10.01
36 INT62919 Regulation of Gnas 22 0.43 5.61 9.55
37 INT106595 Negative_regulation of Dnm2 10 0.58 0.15 9.29
38 INT50055 Negative_regulation of Rac1 36 0.50 19.74 8.98
39 INT26487 Positive_regulation of Npr1 17 0.70 10.01 8.78
40 INT9968 Negative_regulation of Rab38 15 0.00 10.45 8.64
41 INT7663 Positive_regulation of Pck1 15 0.67 3.05 8.63
42 INT1682 Negative_regulation of Rem1 28 0.37 7.38 8.4
43 INT6384 Regulation of Eef1a1 21 0.61 2.95 7.97
44 INT68434 Gene_expression of Gtpbp4 15 0.54 5.5 7.91
45 INT264910 Positive_regulation of Gnaz 1 0.30 0 7.82
46 INT14207 Gene_expression of DNM2 20 0.67 5.76 7.64
47 INT29142 Positive_regulation of Binding of Pck1 10 0.67 1.48 7.6
48 INT152347 Binding of GCH1 8 0.37 6.13 7.36
49 INT30920 Positive_regulation of Gene_expression of Insr 14 0.66 2.91 7.32
50 INT6341 Binding of Gtpbp4 11 0.44 1.54 7.3
51 INT77756 Positive_regulation of GTPBP4 16 0.11 2.6 7.29
52 INT36405 Positive_regulation of Insr 26 0.66 24.5 7.24
53 INT106599 Positive_regulation of Dnm2 8 0.69 0.28 7.01
54 INT18578 Binding of Eef1a1 20 0.48 2.53 6.95
55 INT24622 Positive_regulation of Localization of Insr 15 0.69 0.32 6.85
56 INT26489 Negative_regulation of Npr1 15 0.59 5.7 6.79
57 INT25467 Regulation of Rab38 19 0.00 8.68 6.73
58 INT234813 Gene_expression of RAB5A 58 0.66 3.67 6.48
59 INT6459 Regulation of Negative_regulation of Npr1 10 0.53 0.16 6.44
60 INT7021 Positive_regulation of Negative_regulation of Npr1 8 0.22 1.02 6.36
61 INT103723 Regulation of Positive_regulation of Gtpbp4 5 0.22 1.56 6.35
62 INT11258 Gene_expression of Gnas 58 0.58 21.6 6.33
63 INT67635 Negative_regulation of Gnas 29 0.04 11.4 6.32
64 INT163776 Regulation of GCH1 7 0.27 4.58 6.16
65 INT20899 Negative_regulation of GNAI1 12 0.57 4.24 6.07
66 INT25193 Negative_regulation of Pck1 20 0.57 5.66 6.05
67 INT178604 Gene_expression of TPX2 13 0.37 20.29 6.04
68 INT25271 Positive_regulation of MTG1 21 0.67 13.59 5.96
69 INT6195 Transcription of Npr1 9 0.69 3 5.94
70 INT86799 Gene_expression of Pck1 20 0.65 6.22 5.8
71 INT32611 Phosphorylation of Insr 13 0.80 4.18 5.77
72 INT7018 Positive_regulation of Gene_expression of Npr1 10 0.59 5.09 5.66
73 INT34742 Gene_expression of Gnat3 44 0.67 6.83 5.65
74 INT14769 Positive_regulation of Positive_regulation of Insr 10 0.43 2.66 5.55
75 INT69350 Gene_expression of RAC1 23 0.77 12.16 5.54
76 INT72000 Gene_expression of Gnaq 17 0.75 3.12 5.48
77 INT15367 Gene_expression of OPA1 35 0.67 24.9 5.45
78 INT13706 Localization of Npr1 10 0.59 0.83 5.42
79 INT18577 Negative_regulation of Eef1a1 20 0.39 3.57 5.24
80 INT51950 Positive_regulation of Binding of MTG1 6 0.67 1.05 5.15
81 INT181650 Gene_expression of Glud1 23 0.77 13.66 5.05
82 INT33854 Localization of OPA1 19 0.65 10.55 5.04
83 INT34870 Positive_regulation of OPA1 18 0.59 10.66 5
84 INT114058 Negative_regulation of Gene_expression of Insr 13 0.31 9.23 4.97
85 INT10115 Gene_expression of INSR 31 0.75 11.98 4.86
86 INT51392 Negative_regulation of Insr 18 0.27 14.75 4.84
87 INT11064 Positive_regulation of NPR1 24 0.49 14.63 4.78
88 INT62920 Regulation of Gnai1 3 0.52 0.08 4.78
89 INT255981 Localization of RAB5A 3 0.68 0.88 4.76
90 INT269476 Binding of RAB5A 1 0.41 0 4.76
91 INT128178 Positive_regulation of RHOA 59 0.68 9.3 4.7
92 INT17391 Gene_expression of GNAI1 11 0.75 5.26 4.7
93 INT17393 Positive_regulation of GNAI1 17 0.49 2.42 4.66
94 INT24620 Negative_regulation of Gene_expression of Insr 14 0.39 6.98 4.61
95 INT88909 Positive_regulation of Gene_expression of Dnm1 6 0.70 3.43 4.59
96 INT26546 Positive_regulation of Gene_expression of Hras1 35 0.70 16.59 4.54
97 INT106596 Transcription of Dnm2 4 0.69 0 4.5
98 INT96464 Positive_regulation of GEM 7 0.45 5.48 4.37
99 INT98357 Binding of Gnas 11 0.41 1.87 4.35
100 INT63113 Positive_regulation of HRAS 30 0.67 22.85 4.28
101 INT20981 Binding of HRAS 42 0.48 24.49 4.23
102 INT51084 Binding of Insr 13 0.30 4.25 4.23
103 INT34624 Negative_regulation of REM1 22 0.38 9.25 4.22
104 INT83407 Negative_regulation of Gucy1b2 11 0.58 0.9 4.2
105 INT34829 Positive_regulation of Gnat3 27 0.46 5.24 4.14
106 INT74203 Positive_regulation of Positive_regulation of Gtpbp4 6 0.50 0.33 4.13
107 INT83035 Binding of INSR 16 0.47 9.29 4.11
108 INT32933 Gene_expression of GNAS 57 0.32 10.58 4.03
109 INT109861 Gene_expression of Rhoa 11 0.78 5.67 4.02
110 INT80175 Positive_regulation of Gene_expression of HRAS 24 0.67 14.69 3.97
111 INT169475 Localization of HRAS 14 0.73 9.02 3.9
112 INT112928 Localization of Dnm2 3 0.74 0 3.81
113 INT34441 Negative_regulation of Binding of Pck1 6 0.42 0.76 3.8
114 INT78619 Positive_regulation of RAC1 27 0.65 10.43 3.75
115 INT88906 Gene_expression of Dnm1 5 0.78 10.48 3.7
116 INT157056 Gene_expression of Gucy1a2 4 0.09 0.71 3.67
117 INT25136 Localization of Gnat3 23 0.75 5.01 3.65
118 INT126685 Gene_expression of Rem1 30 0.65 11.21 3.61
119 INT53706 Positive_regulation of Kras 13 0.67 9.26 3.57
120 INT10116 Localization of INSR 11 0.57 5.43 3.48
121 INT24883 Regulation of OPA1 14 0.45 9.73 3.44
122 INT14060 Negative_regulation of Negative_regulation of Insr 6 0.53 3.53 3.44
123 INT121967 Regulation of RAC1 9 0.45 6.14 3.41
124 INT106422 Negative_regulation of Gene_expression of Rac1 4 0.43 3.97 3.41
125 INT117117 Positive_regulation of REM1 12 0.40 10.1 3.33
126 INT135815 Transcription of Gch1 1 0.60 0 3.32
127 INT25466 Binding of Rab38 6 0.00 2.23 3.28
128 INT139010 Regulation of Gfm1 16 0.32 5.02 3.27
129 INT137679 Localization of Gfm1 18 0.08 9.58 3.24
130 INT146194 Negative_regulation of Rhoa 21 0.42 11.05 3.22
131 INT19393 Gene_expression of Gfm1 31 0.51 18.9 3.2
132 INT58475 Localization of Rac1 12 0.75 5.94 3.2
133 INT28166 Positive_regulation of Rem1 8 0.40 7.96 3.19
134 INT12843 Regulation of Pck1 13 0.60 3.46 3.18
135 INT317186 Regulation of BMS1 1 0.04 3.9 3.17
136 INT64748 Regulation of Binding of Pck1 4 0.44 0.45 3.15
137 INT124736 Positive_regulation of Gene_expression of Insr 6 0.31 7.55 3.12
138 INT128179 Gene_expression of RHOA 7 0.64 2.48 3.01
139 INT301081 Positive_regulation of GNAT1 1 0.12 4.16 3
140 INT146191 Gene_expression of Rhoa 32 0.67 17.63 2.92
141 INT5913 Binding of OPA1 12 0.41 9.33 2.92
142 INT17376 Negative_regulation of Binding of MTG1 7 0.57 0.67 2.9
143 INT3605 Negative_regulation of OPA1 14 0.38 10.88 2.84
144 INT54449 Positive_regulation of Transcription of Npr1 3 0.45 1.73 2.81
145 INT99104 Gene_expression of Npr1 5 0.78 3.31 2.8
146 INT136784 Phosphorylation of Eef2 4 0.55 0 2.79
147 INT150933 Negative_regulation of Positive_regulation of GCH1 3 0.58 1.8 2.77
148 INT13943 Localization of DNM2 4 0.52 0.07 2.75
149 INT83404 Positive_regulation of Gucy1b2 9 0.68 5.18 2.74
150 INT121463 Regulation of Localization of Dnm2 2 0.45 0 2.72
151 INT234825 Positive_regulation of Gene_expression of RAB5A 16 0.59 1.15 2.71
152 INT178606 Positive_regulation of Gene_expression of TPX2 4 0.08 8.73 2.71
153 INT11196 Negative_regulation of Gnat3 26 0.37 3.14 2.69
154 INT264915 Positive_regulation of Localization of Gnaz 1 0.19 0 2.68
155 INT62683 Negative_regulation of HRAS 19 0.57 7.93 2.65
156 INT204116 Regulation of Gene_expression of GEM 8 0.29 8.66 2.6
157 INT97452 Positive_regulation of MOCS1 20 0.39 11.4 2.59
158 INT204110 Positive_regulation of Gene_expression of GEM 11 0.67 8.85 2.57
159 INT150932 Positive_regulation of Gene_expression of GCH1 3 0.70 2.07 2.57
160 INT26205 Positive_regulation of Positive_regulation of NPR1 3 0.24 1.57 2.52
161 INT199480 Positive_regulation of DRG1 3 0.02 3.22 2.51
162 INT23527 Negative_regulation of Localization of Insr 10 0.39 2.58 2.5
163 INT80463 Localization of Gucy1a2 4 0.07 0.49 2.5
164 INT130633 Negative_regulation of Gene_expression of Pck1 6 0.37 3.19 2.48
165 INT140363 Negative_regulation of Rhoa 7 0.58 2.49 2.47
166 INT72013 Negative_regulation of Gnai2 5 0.35 0.09 2.44
167 INT44880 Gene_expression of REM1 21 0.30 5.3 2.43
168 INT97453 Negative_regulation of MOCS1 25 0.04 13.4 2.4
169 INT111039 Gene_expression of Kras 20 0.60 15.42 2.39
170 INT79281 Gene_expression of Tgm2 14 0.76 7.46 2.37
171 INT128174 Positive_regulation of Gene_expression of RHOA 7 0.36 1.5 2.36
172 INT86797 Regulation of Gene_expression of Pck1 6 0.44 1.12 2.36
173 INT80194 Transcription of Rab38 4 0.04 1.85 2.35
174 INT139008 Positive_regulation of Gfm1 21 0.35 7.79 2.34
175 INT20873 Negative_regulation of MTG1 6 0.42 1.23 2.34
176 INT127141 Negative_regulation of SUCLG2 1 0.49 0.57 2.34
177 INT65928 Positive_regulation of Gene_expression of Rac1 12 0.42 3.34 2.33
178 INT283973 Transcription of GCH1 1 0.61 1.99 2.33
179 INT11065 Gene_expression of NPR1 6 0.55 3.41 2.32
180 INT146196 Localization of Rhoa 6 0.78 4.68 2.3
181 INT131850 Gene_expression of RHOC 17 0.72 29.06 2.28
182 INT228675 Binding of Fkbp4 1 0.01 1.14 2.28
183 INT283975 Negative_regulation of Localization of GCH1 1 0.38 1.99 2.27
184 INT71268 Positive_regulation of Gene_expression of Eef1a1 7 0.41 1.75 2.26
185 INT71266 Regulation of Gene_expression of Eef1a1 1 0.51 0 2.2
186 INT135827 Positive_regulation of Transcription of Gch1 1 0.58 0 2.2
187 INT24621 Regulation of Gene_expression of Insr 9 0.42 2.68 2.18
188 INT134944 Gene_expression of MOCS1 37 0.06 10.76 2.17
189 INT146192 Positive_regulation of Positive_regulation of Rhoa 8 0.60 8.15 2.17
190 INT70987 Binding of RAC1 14 0.37 12.14 2.13
191 INT6460 Regulation of Gene_expression of Npr1 4 0.52 2.19 2.13
192 INT46849 Regulation of TPX2 5 0.24 6.27 2.1
193 INT179311 Transcription of GNAS 2 0.10 0.67 2.08
194 INT69196 Positive_regulation of Rap1a 2 0.29 1.18 2.06
195 INT31006 Regulation of Localization of Insr 7 0.50 0.2 2.05
196 INT108903 Negative_regulation of GNAS 7 0.57 1.58 2.04
197 INT17390 Regulation of GNAI1 5 0.04 3.58 2.03
198 INT258637 Regulation of Gene_expression of GCH1 1 0.62 1.77 2.02
199 INT65993 Localization of Gnai1 1 0.46 0.08 2
200 INT112880 Positive_regulation of Gnaq 17 0.49 1.97 1.95
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