GO:0005583

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Name fibrillar collagen
Categary Component
Go Slim No
Go Link GO:0005583
Unique Molecular Interactions 53
Total Molecular Interactions 71
Total Single Events 679
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for fibrillar collagen. They are ordered first by their pain relevance and then by number of times they were reported for fibrillar collagen. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT194856 Positive_regulation of Adora2b Negative_regulation of Positive_regulation of Mmp13 1 0.01 0.73 0.85
2 INT162241 Binding of COL7A1 and MMP13 2 0.03 0.86 0.73
3 INT182266 EDN1 Positive_regulation of Gene_expression of MMP13 1 0.35 2.03 0.63
4 INT178087 EDN1 Positive_regulation of MMP13 2 0.23 1.58 0.59
5 INT345303 MMP15 Positive_regulation of MMP13 1 0.00 1.18 0.58
6 INT202043 MMP13 Regulation of Protein_catabolism of COL2A1 1 0.01 0.54 0.54
7 INT173597 Negative_regulation of Binding of MMP2 and Mmp13 1 0.14 0.83 0.48
8 INT173595 Binding of MMP2 and Mmp13 1 0.12 0.83 0.48
9 INT173596 Binding of MMP3 and Mmp13 1 0.06 0.84 0.48
10 INT173598 Negative_regulation of Binding of MMP3 and Mmp13 1 0.06 0.84 0.48
11 INT345305 MMP14 Positive_regulation of MMP13 1 0.00 0.33 0.45
12 INT224686 S100a4 Positive_regulation of Gene_expression of Mmp13 1 0.05 0.85 0.45
13 INT312086 ELANE Positive_regulation of MMP13 1 0.13 0.64 0.39
14 INT288164 Jun Regulation of Gene_expression of Mmp13 1 0.02 0.41 0.35
15 INT288167 Ugcg Negative_regulation of Gene_expression of Mmp13 1 0.06 0.46 0.35
16 INT194859 IL1B Positive_regulation of Gene_expression of MMP13 2 0.52 0.86 0.33
17 INT323870 LEP Regulation of Gene_expression of MMP13 1 0.21 1.76 0.33
18 INT328224 Col2a1 Positive_regulation of Gene_expression of Mmp13 1 0.04 0.8 0.29
19 INT328223 Mmp14 Regulation of Positive_regulation of Mmp13 1 0.07 0.69 0.29
20 INT336335 Glp2r Regulation of Mmp13 1 0.06 0.68 0.28
21 INT328222 Mmp2 Regulation of Positive_regulation of Mmp13 1 0.05 0.69 0.28
22 INT180964 PLG Positive_regulation of MMP13 1 0.24 0.45 0.25
23 INT311911 Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23
24 INT311908 Acvrl1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23
25 INT182272 EDN1 Regulation of Gene_expression of MMP13 1 0.26 0.87 0.22
26 INT264526 PTGDS Negative_regulation of Gene_expression of MMP13 1 0.12 0.5 0.22
27 INT254687 Positive_regulation of Map2k1 Positive_regulation of Gene_expression of Mmp13 1 0.06 0.2 0.2
28 INT182271 EDN1 Positive_regulation of Localization of MMP13 1 0.27 0.47 0.19
29 INT220213 Mmp13 Regulation of Protein_catabolism of COL2A1 1 0.49 0.29 0.14
30 INT264399 Binding of IL1B and MMP13 1 0.39 0.08 0.13
31 INT311912 Gene_expression of Smad1 Positive_regulation of Gene_expression of Mmp13 1 0.08 0.51 0.12
32 INT264397 MMP9 Regulation of Positive_regulation of MMP13 1 0.20 0.06 0.12
33 INT264389 MMP14 Regulation of Positive_regulation of MMP13 1 0.31 0.06 0.12
34 INT264381 MMP3 Regulation of Positive_regulation of MMP13 1 0.21 0.06 0.12
35 INT323886 BMI1 Regulation of Gene_expression of MMP13 1 0.01 1.13 0.12
36 INT323882 Binding of BMI1 and MMP13 1 0.01 1.26 0.11
37 INT311917 Gene_expression of Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.31 0.08
38 INT138133 Nfkb1 Regulation of Positive_regulation of Mmp13 1 0.00 0.31 0.07
39 INT311915 Tgfbr1 Negative_regulation of Gene_expression of Mmp13 1 0.09 0.27 0.06
40 INT311903 Acvrl1 Negative_regulation of Gene_expression of Mmp13 1 0.09 0.27 0.06
41 INT311916 Smad3 Negative_regulation of Gene_expression of Mmp13 1 0.12 0.27 0.06
42 INT323878 Binding of LEP and MMP13 1 0.17 0.77 0.05
43 INT220239 IL1B Positive_regulation of MMP13 1 0.23 0 0.04
44 INT180956 PLG Regulation of Positive_regulation of MMP13 1 0.32 0.38 0.04
45 INT180957 Binding of PLG and Regulation of Positive_regulation of MMP13 1 0.14 0.38 0.04
46 INT264393 MMP1 Positive_regulation of Gene_expression of MMP13 1 0.29 0.14 0.04
47 INT220909 GNS Negative_regulation of Gene_expression of MMP13 1 0.00 0 0.03
48 INT220915 GNS Negative_regulation of MMP13 1 0.00 0 0.03
49 INT264380 Binding of JUN and MMP13 1 0.05 0 0
50 INT264407 Binding of DR1 and MMP13 1 0.08 0 0
51 INT264383 MMP1 Regulation of Binding of MMP13 1 0.28 0 0
52 INT264378 MMP1 Regulation of Transcription of MMP13 1 0.28 0 0
53 INT264404 MMP13 Regulation of Binding of MMP1 1 0.28 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for fibrillar collagen. They are ordered first by their pain relevance and then by number of times they were reported in fibrillar collagen. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT129956 Gene_expression of MMP13 145 0.72 60.48 26.98
2 INT116282 Gene_expression of Mmp13 83 0.75 45.4 20.18
3 INT1284 Negative_regulation of Mmp13 20 0.57 36.21 14.91
4 INT123779 Positive_regulation of MMP13 42 0.65 24.3 12.45
5 INT140191 Positive_regulation of Gene_expression of Mmp13 25 0.67 13.47 9.71
6 INT129962 Positive_regulation of Gene_expression of MMP13 41 0.65 20.74 8.54
7 INT168383 Positive_regulation of Mmp13 27 0.67 17.9 6.27
8 INT141146 Gene_expression of Mmp13 18 0.38 8.61 5.54
9 INT1285 Localization of Mmp13 12 0.78 8.98 4.93
10 INT129964 Negative_regulation of MMP13 23 0.55 6.48 4.21
11 INT149614 Localization of MMP13 13 0.81 6.12 3.65
12 INT32464 Regulation of Mmp13 12 0.44 6.46 3.61
13 INT129960 Negative_regulation of Gene_expression of MMP13 19 0.53 7.17 3.55
14 INT116281 Negative_regulation of Gene_expression of Mmp13 15 0.41 9.96 3.41
15 INT120106 Negative_regulation of Mmp13 8 0.51 2.25 2.08
16 INT116280 Transcription of Mmp13 11 0.67 6.52 2.06
17 INT145235 Protein_catabolism of Mmp13 3 0.89 2.46 2.03
18 INT182295 Regulation of MMP13 6 0.27 3.33 1.77
19 INT141147 Negative_regulation of Gene_expression of Mmp13 5 0.12 1.37 1.59
20 INT120111 Regulation of Mmp13 4 0.29 2.65 1.48
21 INT129963 Regulation of Gene_expression of MMP13 8 0.42 2.84 1.39
22 INT148740 Regulation of Gene_expression of Mmp13 1 0.03 2.58 1.37
23 INT123778 Positive_regulation of Positive_regulation of MMP13 4 0.25 2.51 1.34
24 INT170294 Regulation of Gene_expression of Mmp13 5 0.44 4.25 1.26
25 INT120108 Transcription of Mmp13 3 0.51 0.22 1.22
26 INT317972 Positive_regulation of Transcription of Mmp13 5 0.41 3.83 1.21
27 INT220926 Transcription of MMP13 12 0.67 3.03 1.09
28 INT170321 Binding of Mmp13 3 0.36 2.54 1.09
29 INT173552 Protein_catabolism of Mmp13 5 0.96 3.05 1.01
30 INT316724 Negative_regulation of Localization of Mmp13 1 0.13 0.63 1
31 INT130005 Protein_catabolism of MMP13 4 0.36 3.02 0.95
32 INT224483 Regulation of Regulation of MMP13 2 0.15 1.16 0.86
33 INT338119 Negative_regulation of Transcription of Mmp13 1 0.09 0 0.86
34 INT120113 Positive_regulation of Mmp13 5 0.70 2.02 0.64
35 INT305480 Regulation of Protein_catabolism of Mmp13 1 0.29 0.73 0.64
36 INT274679 Regulation of Negative_regulation of Mmp13 2 0.43 1.78 0.57
37 INT5009 Positive_regulation of Negative_regulation of Mmp13 1 0.06 0.1 0.42
38 INT173575 Binding of MMP13 2 0.35 0.79 0.36
39 INT220928 Positive_regulation of Transcription of MMP13 4 0.47 1.93 0.33
40 INT264548 Negative_regulation of Positive_regulation of MMP13 1 0.11 0.79 0.31
41 INT328216 Regulation of Transcription of Mmp13 1 0.37 0.35 0.28
42 INT145234 Binding of Mmp13 1 0.37 0.43 0.23
43 INT168380 Positive_regulation of Positive_regulation of Mmp13 2 0.49 0.48 0.22
44 INT157603 Positive_regulation of Gene_expression of Mmp13 3 0.16 0.91 0.21
45 INT195439 Negative_regulation of Regulation of Mmp13 1 0.41 0.53 0.2
46 INT220938 Negative_regulation of Transcription of MMP13 2 0.40 0.32 0.19
47 INT264448 Positive_regulation of Negative_regulation of MMP13 1 0.47 0.38 0.16
48 INT240145 Positive_regulation of Localization of MMP13 1 0.18 0.27 0.12
49 INT116283 Negative_regulation of Transcription of Mmp13 1 0.42 1.01 0.08
50 INT264422 Negative_regulation of Binding of MMP13 1 0.40 0 0.07
51 INT240150 Regulation of Binding of MMP13 1 0.16 0 0
52 INT182278 Negative_regulation of Phosphorylation of MMP13 1 0.21 0.17 0
53 INT120107 Positive_regulation of Transcription of Mmp13 1 0.03 0 0
54 INT182287 Phosphorylation of MMP13 1 0.40 0.17 0
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