GO:0005584

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Name collagen type I
Categary Component
Go Slim No
Go Link GO:0005584
Unique Molecular Interactions 106
Total Molecular Interactions 111
Total Single Events 1584
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for collagen type I. They are ordered first by their pain relevance and then by number of times they were reported for collagen type I. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT157460 CX3CL1 Regulation of Gene_expression of COL1A1 1 0.11 1.57 1.37
2 INT222979 Negative_regulation of Binding of COL1A1 and FN1 1 0.01 1.64 0.93
3 INT222978 Binding of COL1A1 and FN1 1 0.01 1.64 0.92
4 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 0.01 1.66 0.9
5 INT135781 Cyp3a23/3a1 Positive_regulation of Positive_regulation of Col1a1 1 0.01 0.78 0.8
6 INT192159 Mmp14 Regulation of Protein_catabolism of Col1a1 1 0.02 1.01 0.52
7 INT320810 Protein_catabolism of COL1A2 Positive_regulation of Localization of CYP27A1 1 0.04 1.05 0.4
8 INT149896 Ihh Regulation of Gene_expression of Col1a1 1 0.06 0.89 0.33
9 INT137033 Tgfb1 Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
10 INT225101 TGFB1 Positive_regulation of Localization of COL1A1 1 0.03 0.59 0.28
11 INT137014 Positive_regulation of Pscs Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
12 INT225100 TGFB1 Positive_regulation of Gene_expression of COL1A1 1 0.04 0.59 0.28
13 INT137012 Pscs Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
14 INT271446 Thy1 Regulation of Col1a1 1 0.05 0.61 0.25
15 INT252784 ROS1 Positive_regulation of Gene_expression of COL1A1 1 0.05 1.86 0.24
16 INT316810 Sparc Regulation of Col1a1 1 0.13 0.48 0.21
17 INT353285 Prdx2 Regulation of Gene_expression of Col1a2 1 0.02 0.73 0.21
18 INT225099 ZNF630 Positive_regulation of Gene_expression of COL1A1 1 0.00 0.17 0.2
19 INT185793 SPP1 Positive_regulation of COL1A2 1 0.16 0.33 0.16
20 INT264868 Binding of COL1A2 and GOPC 1 0.02 0.3 0.15
21 INT157602 Binding of COL1A1 and COL3A1 1 0.04 0 0.13
22 INT316813 Sparc Negative_regulation of Gene_expression of Col1a1 1 0.13 0.67 0.12
23 INT323869 Binding of BMI1 and COL1A2 1 0.00 1.21 0.11
24 INT294445 KLK4 Negative_regulation of COL1A1 1 0.01 0 0.1
25 INT205055 MMP3 Negative_regulation of COL1A2 1 0.32 1.52 0.1
26 INT179869 COL1A1 Positive_regulation of SOCS3 1 0.04 0.99 0.1
27 INT207459 LGALS3 Regulation of Gene_expression of COL1A2 1 0.06 0.21 0.1
28 INT323868 LEP Regulation of Transcription of COL1A2 1 0.10 0.98 0.09
29 INT58630 Calca Negative_regulation of Positive_regulation of COL1A1 1 0.02 0.23 0.08
30 INT323876 LEP Regulation of COL1A2 1 0.10 0.86 0.08
31 INT222983 TNF Positive_regulation of Positive_regulation of COL1A1 1 0.01 0.71 0.08
32 INT218710 MMP1 Regulation of Positive_regulation of Col1a1 1 0.00 0.15 0.07
33 INT180668 Edn1 Positive_regulation of Gene_expression of Col1a1 1 0.02 0 0.05
34 INT220081 Binding of COL1A1 and MMRN1 1 0.00 0.36 0.05
35 INT222980 TNF Positive_regulation of Localization of COL1A1 1 0.01 0.56 0.04
36 INT199526 Ceacam1 Negative_regulation of Col1a1 1 0.01 0.06 0.03
37 INT222977 Positive_regulation of COL1A1 Positive_regulation of MMP1 1 0.01 0.61 0.03
38 INT222987 Positive_regulation of COL1A1 Positive_regulation of Protein_catabolism of MMP1 1 0.01 0.61 0.03
39 INT170329 Binding of Col4a1 and Col1a1 1 0.03 0.14 0.03
40 INT180565 HEYL Positive_regulation of Negative_regulation of COL1A1 1 0.01 0 0.03
41 INT180571 HEYL Positive_regulation of Protein_catabolism of COL1A1 1 0.01 0 0.03
42 INT170331 Binding of Col7a1 and Col1a1 1 0.00 0.14 0.03
43 INT252820 ELANE Positive_regulation of Gene_expression of COL1A1 1 0.01 0.58 0
44 INT312224 INPP5K Regulation of Negative_regulation of COL1A1 1 0.08 0 0
45 INT263900 Binding of Col1a1 and Cea 1 0.01 0.63 0
46 INT252796 ELANE Regulation of COL1A1 1 0.01 0.57 0
47 INT180847 Binding of COL1A1 and NID2 1 0.05 0.91 0
48 INT184210 IL1B Negative_regulation of Gene_expression of COL1A2 1 0.04 0 0
49 INT312214 INPP5K Regulation of Gene_expression of COL1A1 1 0.08 0 0
50 INT316811 Negative_regulation of Col1a2 Negative_regulation of Col3a1 1 0.33 0.07 0
51 INT252773 ROS1 Positive_regulation of COL1A1 1 0.05 0.57 0
52 INT252800 ROS1 Regulation of COL1A1 1 0.05 0.57 0
53 INT252813 ELANE Positive_regulation of COL1A1 1 0.01 0.57 0
54 INT118660 Binding of COL1A1 and GAPDH 1 0.16 0.09 0
55 INT255385 Binding of COL1A2 and DSPP 1 0.40 0.12 0
56 INT96782 FAM176C Regulation of Gene_expression of COL1A1 1 0.32 0.05 0
57 INT180859 Binding of COL1A1 and NID1 1 0.01 0.9 0
58 INT252802 ROS1 Regulation of Gene_expression of COL1A1 1 0.05 0.58 0
59 INT252776 ELANE Regulation of Gene_expression of COL1A1 1 0.01 0.58 0
60 INT206621 Col1a1 Positive_regulation of Col3a1 1 0.00 0.28 0
61 INT316821 Col1a2 Negative_regulation of Col3a1 1 0.33 0.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for collagen type I. They are ordered first by their pain relevance and then by number of times they were reported in collagen type I. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT19963 Gene_expression of COL1A1 118 0.59 42.11 15.15
2 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29
3 INT19086 Negative_regulation of COL1A1 32 0.38 16.77 5.98
4 INT84561 Binding of COL1A2 18 0.47 11.76 5.09
5 INT69215 Gene_expression of Col1a1 38 0.68 17.39 4.77
6 INT19965 Positive_regulation of COL1A1 23 0.45 14.49 4.38
7 INT156137 Gene_expression of Col1a2 28 0.73 13.3 3.99
8 INT49238 Protein_catabolism of COL1A2 30 0.97 15.64 3.45
9 INT81229 Binding of COL1A1 24 0.35 12.07 3.3
10 INT67719 Positive_regulation of Col1a1 21 0.44 8.87 3.12
11 INT68091 Localization of COL1A1 19 0.66 9.13 2.56
12 INT8890 Transcription of Col1a1 10 0.63 4.02 2.48
13 INT79261 Positive_regulation of Gene_expression of COL1A1 24 0.36 7.49 2.45
14 INT97152 Protein_catabolism of COL1A1 11 0.74 8.03 2.3
15 INT61684 Localization of COL1A2 20 0.73 9.31 2.26
16 INT126513 Gene_expression of Col1a1 23 0.75 10.92 2.18
17 INT89519 Negative_regulation of COL1A2 10 0.36 6.26 2.17
18 INT113717 Negative_regulation of Gene_expression of COL1A1 21 0.41 6.14 2.01
19 INT120857 Localization of Col1a1 10 0.71 2.33 1.93
20 INT152155 Positive_regulation of Col1a2 7 0.56 10.18 1.89
21 INT96116 Transcription of COL1A1 10 0.44 4.57 1.81
22 INT84375 Regulation of COL1A2 6 0.44 8.75 1.72
23 INT139317 Negative_regulation of Col1a2 8 0.41 7.17 1.54
24 INT153201 Negative_regulation of Gene_expression of Col1a1 7 0.38 6.37 1.52
25 INT142719 Binding of Col1a1 7 0.34 5.83 1.47
26 INT62669 Positive_regulation of COL1A2 13 0.49 6.89 1.4
27 INT120860 Positive_regulation of Gene_expression of Col1a1 12 0.44 4.84 1.34
28 INT112650 Positive_regulation of Col1a1 3 0.30 5.96 1.3
29 INT59473 Negative_regulation of Col1a1 4 0.25 1.33 1.24
30 INT71845 Positive_regulation of Positive_regulation of Col1a1 1 0.34 0.15 1.23
31 INT140033 Positive_regulation of Gene_expression of Col1a1 6 0.14 3.68 1.2
32 INT101104 Positive_regulation of Gene_expression of COL1A2 12 0.69 5.87 1.09
33 INT133102 Negative_regulation of Gene_expression of COL1A2 8 0.08 2.56 1.02
34 INT156614 Regulation of Gene_expression of COL1A1 6 0.33 2.51 0.99
35 INT129997 Protein_catabolism of Col1a1 5 0.96 3.43 0.96
36 INT155867 Transcription of COL1A2 8 0.69 2.9 0.94
37 INT204547 Positive_regulation of Gene_expression of Col1a2 2 0.04 2.08 0.91
38 INT8888 Regulation of Col1a1 4 0.13 1.97 0.86
39 INT192156 Negative_regulation of Col1a1 6 0.39 3.92 0.8
40 INT91384 Positive_regulation of Localization of COL1A2 3 0.49 1.42 0.71
41 INT156138 Negative_regulation of Gene_expression of Col1a2 2 0.55 2.07 0.7
42 INT89520 Regulation of COL1A1 8 0.32 3.21 0.66
43 INT68092 Negative_regulation of Localization of COL1A1 1 0.48 0 0.53
44 INT129999 Protein_catabolism of Col1a2 3 0.96 1.21 0.52
45 INT8886 Regulation of Transcription of Col1a1 1 0.04 0 0.5
46 INT320812 Positive_regulation of Localization of COL1A1 1 0.05 1.04 0.4
47 INT63550 Positive_regulation of Protein_catabolism of COL1A2 4 0.25 3.22 0.38
48 INT130739 Binding of Col1a2 2 0.35 2.38 0.34
49 INT155865 Positive_regulation of Transcription of COL1A2 2 0.46 0.6 0.34
50 INT163709 Regulation of Negative_regulation of COL1A1 1 0.29 0.93 0.34
51 INT65208 Positive_regulation of Positive_regulation of COL1A2 3 0.14 2.63 0.32
52 INT254811 Localization of Col1a1 3 0.29 1.39 0.3
53 INT291615 Negative_regulation of Localization of Col1a1 1 0.06 1.28 0.3
54 INT126512 Negative_regulation of Gene_expression of Col1a1 3 0.39 2.2 0.27
55 INT176464 Protein_catabolism of Col1a1 1 0.19 0.83 0.26
56 INT271432 Positive_regulation of Regulation of Col1a1 1 0.10 0.61 0.24
57 INT225109 Regulation of Localization of COL1A1 1 0.05 0.41 0.23
58 INT302405 Transcription of Col1a2 3 0.55 1.82 0.21
59 INT218694 Binding of Col1a1 2 0.21 1.52 0.21
60 INT96582 Negative_regulation of Protein_catabolism of COL1A2 1 0.37 0.2 0.21
61 INT143923 Regulation of Positive_regulation of COL1A2 1 0.02 0.86 0.2
62 INT120859 Positive_regulation of Localization of Col1a1 1 0.16 0.05 0.18
63 INT187816 Positive_regulation of Transcription of Col1a1 1 0.06 0.82 0.17
64 INT130000 Positive_regulation of Protein_catabolism of Col1a1 1 0.49 1.15 0.15
65 INT129996 Positive_regulation of Protein_catabolism of Col1a2 1 0.49 1.15 0.15
66 INT187815 Transcription of Col1a1 1 0.09 0.76 0.15
67 INT73297 Positive_regulation of Transcription of Col1a1 2 0.32 3.12 0.14
68 INT257290 Negative_regulation of Transcription of COL1A1 3 0.27 1.64 0.13
69 INT97305 Positive_regulation of Binding of COL1A2 1 0.49 0.27 0.1
70 INT179886 Negative_regulation of Negative_regulation of COL1A1 1 0.05 0.5 0.05
71 INT180589 Phosphorylation of COL1A1 3 0.34 0.37 0.03
72 INT133103 Negative_regulation of Localization of COL1A2 2 0.04 1.49 0.03
73 INT316800 Regulation of Col1a2 2 0.25 0.34 0.03
74 INT222999 Positive_regulation of Positive_regulation of COL1A1 1 0.04 0.61 0.03
75 INT180582 Negative_regulation of Phosphorylation of COL1A1 1 0.07 0 0.03
76 INT180579 Negative_regulation of Protein_catabolism of COL1A1 1 0.07 0 0.03
77 INT206617 Regulation of Gene_expression of Col1a1 2 0.06 0.49 0
78 INT257285 Positive_regulation of Transcription of COL1A1 2 0.29 1.23 0
79 INT245725 Positive_regulation of Negative_regulation of Col1a1 1 0.21 0.7 0
80 INT252761 Positive_regulation of Regulation of COL1A1 1 0.08 0.17 0
81 INT349649 Negative_regulation of Localization of Col1a1 1 0.04 0 0
82 INT264310 Regulation of Col1a1 1 0.19 0 0
83 INT316807 Positive_regulation of Regulation of Col1a2 1 0.44 0.1 0
84 INT277704 Regulation of Regulation of COL1A1 1 0.08 0.61 0
85 INT209434 Negative_regulation of Protein_catabolism of Col1a1 1 0.10 0 0
86 INT254803 Positive_regulation of Localization of Col1a1 1 0.10 0.11 0
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