GO:0005585

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Name collagen type II
Categary Component
Go Slim No
Go Link GO:0005585
Unique Molecular Interactions 59
Total Molecular Interactions 76
Total Single Events 1061
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for collagen type II. They are ordered first by their pain relevance and then by number of times they were reported for collagen type II. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT311914 Il1 Negative_regulation of Gene_expression of Col2a1 1 0.01 1.94 1.23
2 INT204551 Binding of Col2a1 and Positive_regulation of Cia1 1 0.03 1.74 1.03
3 INT202043 MMP13 Regulation of Protein_catabolism of COL2A1 1 0.01 0.54 0.54
4 INT312122 ELANE Positive_regulation of Protein_catabolism of COL2A1 1 0.05 0.65 0.39
5 INT254344 Binding of Col2a1 and Ncoa5 1 0.00 0.98 0.35
6 INT264523 PTGDS Positive_regulation of Gene_expression of COL2A1 1 0.03 1.24 0.3
7 INT220194 PTGER2 Negative_regulation of COL2A1 1 0.26 0.55 0.29
8 INT328224 Col2a1 Positive_regulation of Gene_expression of Mmp13 1 0.04 0.8 0.29
9 INT60347 COL2A1 Positive_regulation of Gene_expression of Hras 1 0.05 0.92 0.2
10 INT220190 PTGER2 Regulation of COL2A1 1 0.32 0.92 0.18
11 INT220191 Binding of COL2A1 and PTGER2 1 0.22 0.35 0.18
12 INT346305 Binding of ELANE and Col2a1 1 0.00 0.98 0.17
13 INT336337 Glp2r Positive_regulation of Gene_expression of Col2a1 1 0.01 0.7 0.14
14 INT293867 Binding of COL2A1 and MEFV 1 0.01 0.52 0.14
15 INT220213 Mmp13 Regulation of Protein_catabolism of COL2A1 1 0.49 0.29 0.14
16 INT326974 BMP2 Positive_regulation of Gene_expression of COL2A1 1 0.07 0.27 0.11
17 INT220195 PTGER2 Negative_regulation of Localization of COL2A1 1 0.26 0.51 0.09
18 INT346304 Col2a1 Positive_regulation of Localization of PTGER2 1 0.00 0.18 0.09
19 INT288003 Binding of COL2A1 and PADI1 1 0.09 0.11 0.06
20 INT346302 ELANE Regulation of Col2a1 1 0.00 0.3 0.05
21 INT220189 Binding of COL2A1 and TIMP1 1 0.04 0.1 0.05
22 INT323807 NFAT5 Regulation of Gene_expression of COL2A1 1 0.29 0.19 0.04
23 INT346303 Binding of MR1 and Col2a1 1 0.00 0.09 0.04
24 INT220196 Binding of PTGER2 and Negative_regulation of Gene_expression of COL2A1 1 0.26 0.77 0.04
25 INT322891 Sox9 Regulation of Transcription of Col2a1 1 0.10 0.12 0.04
26 INT233397 Binding of ABCA4 and COL2A1 1 0.38 3.59 0.03
27 INT220245 IL1RN Regulation of Protein_catabolism of COL2A1 1 0.09 0 0.03
28 INT293869 Binding of COL2A1 and GREM1 1 0.00 1.11 0
29 INT288002 Binding of COL2A1 and GOPC 1 0.12 0 0
30 INT63391 SLTM Regulation of Gene_expression of Col2a1 1 0.00 0 0
31 INT312230 INPP5K Regulation of Gene_expression of COL2A1 1 0.06 0 0
32 INT147529 TGFB1 Negative_regulation of Gene_expression of Col2a1 1 0.05 0.32 0
33 INT88567 COL2A1 Positive_regulation of A1cf 1 0.09 0.36 0
34 INT312227 INPP5K Regulation of Negative_regulation of COL2A1 1 0.06 0 0
35 INT312345 Binding of COL2A1 and COL5A2 1 0.00 1.21 0
36 INT323804 NFAT5 Regulation of Transcription of COL2A1 1 0.43 0.07 0
37 INT312213 INPP5K Regulation of COL2A1 1 0.06 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for collagen type II. They are ordered first by their pain relevance and then by number of times they were reported in collagen type II. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58
2 INT37618 Gene_expression of Col2a1 50 0.70 33.88 11.58
3 INT54834 Gene_expression of Col2a1 48 0.72 13.5 9.41
4 INT130731 Protein_catabolism of COL2A1 47 0.96 21.86 9.28
5 INT20552 Negative_regulation of Gene_expression of COL2A1 29 0.56 11.92 4.81
6 INT217742 Positive_regulation of Gene_expression of COL2A1 20 0.67 9.76 4.23
7 INT124815 Binding of Col2a1 9 0.37 10.27 3.93
8 INT53021 Positive_regulation of COL2A1 29 0.55 27.75 3.47
9 INT130729 Negative_regulation of Protein_catabolism of COL2A1 15 0.42 7.59 3.35
10 INT39867 Binding of Col2a1 9 0.35 7.65 3.18
11 INT54832 Negative_regulation of Gene_expression of Col2a1 6 0.50 2.53 3.16
12 INT171884 Positive_regulation of Gene_expression of Col2a1 11 0.23 8.04 3.02
13 INT20551 Negative_regulation of COL2A1 31 0.55 21.98 2.66
14 INT96693 Binding of COL2A1 45 0.46 37.11 2.61
15 INT164407 Negative_regulation of Gene_expression of Col2a1 6 0.39 4 1.78
16 INT220992 Protein_catabolism of Col2a1 8 0.40 5.55 1.64
17 INT164410 Negative_regulation of Col2a1 4 0.39 3.75 1.53
18 INT32184 Negative_regulation of Col2a1 9 0.42 3.05 1.43
19 INT54831 Regulation of Gene_expression of Col2a1 4 0.39 2.3 1.31
20 INT117232 Localization of COL2A1 11 0.72 7.34 1.3
21 INT128714 Transcription of Col2a1 6 0.52 2.13 1.24
22 INT176463 Protein_catabolism of Col2a1 4 0.35 1.94 1.2
23 INT11658 Regulation of Gene_expression of COL2A1 9 0.62 3.09 1.11
24 INT54835 Regulation of Col2a1 5 0.59 2.08 1.07
25 INT168233 Positive_regulation of Transcription of Col2a1 2 0.45 1.78 0.99
26 INT173506 Positive_regulation of Col2a1 4 0.20 3.42 0.76
27 INT37617 Regulation of Gene_expression of Col2a1 3 0.31 1.48 0.7
28 INT63389 Localization of Col2a1 7 0.68 1.95 0.6
29 INT32183 Positive_regulation of Negative_regulation of Col2a1 2 0.46 1.01 0.49
30 INT125840 Positive_regulation of Binding of Col2a1 1 0.43 1.21 0.45
31 INT9732 Regulation of COL2A1 9 0.58 6.93 0.44
32 INT54833 Positive_regulation of Col2a1 5 0.52 1.1 0.32
33 INT180577 Positive_regulation of Protein_catabolism of COL2A1 2 0.12 0.91 0.31
34 INT220209 Negative_regulation of Localization of COL2A1 1 0.41 0.48 0.29
35 INT181524 Negative_regulation of Binding of Col2a1 1 0.13 1.05 0.25
36 INT275310 Positive_regulation of Protein_catabolism of Col2a1 1 0.16 0.88 0.22
37 INT220208 Regulation of Protein_catabolism of COL2A1 1 0.26 0.28 0.17
38 INT63646 Localization of Col2a1 3 0.77 0.37 0.16
39 INT95278 Positive_regulation of Gene_expression of Col2a1 2 0.47 0.21 0.13
40 INT221000 Phosphorylation of COL2A1 1 0.19 0.18 0.12
41 INT203079 Regulation of Transcription of Col2a1 1 0.05 0.07 0.11
42 INT346288 Phosphorylation of Col2a1 1 0.02 0.73 0.08
43 INT231709 Negative_regulation of Negative_regulation of Col2a1 1 0.27 0.18 0.06
44 INT339669 Regulation of Col2a1 1 0.01 1.02 0.05
45 INT250505 Positive_regulation of Negative_regulation of COL2A1 1 0.41 0.57 0.05
46 INT272249 Negative_regulation of Negative_regulation of COL2A1 1 0.06 0 0.05
47 INT201964 Transcription of Col2a1 2 0.38 0.55 0.04
48 INT346287 Regulation of Binding of Col2a1 1 0.01 0.07 0.04
49 INT184729 Transcription of COL2A1 4 0.67 1.1 0
50 INT165862 Positive_regulation of Binding of COL2A1 2 0.43 0 0
51 INT312246 Regulation of Negative_regulation of COL2A1 1 0.07 0 0
52 INT176462 Positive_regulation of Protein_catabolism of Col2a1 1 0.16 0.21 0
53 INT264309 Regulation of Localization of Col2a1 1 0.26 0 0
54 INT322897 Negative_regulation of Transcription of COL2A1 1 0.17 0 0
55 INT63388 Positive_regulation of Localization of Col2a1 1 0.01 0.16 0
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