GO:0005615

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Name extracellular space
Categary Component
Go Slim Yes
Go Link GO:0005615
Unique Molecular Interactions 26360
Total Molecular Interactions 38423
Total Single Events 357882
Pain Genes Associated 1083

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for extracellular space. They are ordered first by their pain relevance and then by number of times they were reported for extracellular space. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69872 Binding of MC1R and POMC 52 0.54 8.87 18.3
2 INT6078 Pomc Positive_regulation of Localization of Penk 13 0.51 0 15.49
3 INT2161 Gnrh1 Positive_regulation of Localization of LH 33 0.73 0.87 14.34
4 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 0.64 2.12 14.2
5 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
6 INT166591 Binding of CALCA and DCLK3 4 0.30 0.69 12.18
7 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25
8 INT10161 Binding of Cck and Penk 6 0.53 0.97 11.15
9 INT10268 Binding of PDYN and POMC 11 0.39 0.08 10.36
10 INT6079 Pomc Positive_regulation of Penk 9 0.43 0 9.46
11 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26
12 INT26468 Ghrh Positive_regulation of Localization of Gh 21 0.37 3.26 9.21
13 INT2714 Pomc Positive_regulation of Localization of Prl 17 0.79 0.5 8.18
14 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
15 INT11250 Cck Positive_regulation of Gene_expression of Fos 14 0.78 0.08 7.29
16 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
17 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 0.76 8.19 6.66
18 INT140015 Avp Positive_regulation of Localization of Penk 3 0.63 3.48 6.63
19 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62
20 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49
21 INT251170 Clu Positive_regulation of Trpv1 1 0.28 2.61 6.49
22 INT91538 Pomc Positive_regulation of P9Ehs1 6 0.11 1.47 6.23
23 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1
24 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 0.74 4.31 6.1
25 INT176477 Binding of CXCR3 and CXCL10 14 0.25 10.61 5.87
26 INT169218 Binding of EGFR and Coc 1 0.06 2.8 5.85
27 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
28 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
29 INT79759 Ngf Regulation of Il6 1 0.60 4.62 5.62
30 INT140935 Binding of Cd40lg and Cd40 1 0.30 6.34 5.61
31 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
32 INT92466 Pomc Positive_regulation of Binding of Crygs 8 0.06 0 5.56
33 INT227157 Binding of PEBP1 and Gpm6a 1 0.00 1.28 5.52
34 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27
35 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23
36 INT15842 Crh Positive_regulation of Localization of Pomc 15 0.73 5 5.05
37 INT1310 Pomc Regulation of Localization of Prl 9 0.40 0.61 4.96
38 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
39 INT102122 Binding of Calca and RT1-M4 7 0.29 5.83 4.94
40 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
41 INT166590 Binding of RAMP1 and DCLK3 2 0.37 0.39 4.8
42 INT10844 Ghrh Regulation of Gh 13 0.13 4.77 4.71
43 INT29206 Crh Regulation of Localization of POMC 4 0.64 0.96 4.68
44 INT24742 Binding of Calca and Vip 1 0.37 0.18 4.68
45 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
46 INT34444 Binding of Oprl1 and Ptprg 4 0.03 0.18 4.58
47 INT51497 Cck Negative_regulation of Localization of Trim13 1 0.34 0 4.53
48 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
49 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
50 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
51 INT32444 Binding of Cpe and Pomc 2 0.22 0 4.47
52 INT38217 Penk Regulation of Localization of Avp 2 0.38 0.56 4.45
53 INT30423 Penk Regulation of Localization of Ins1 4 0.26 0.77 4.42
54 INT36536 PRSS1 Positive_regulation of PENK 1 0.24 0.86 4.39
55 INT180774 Gdnf Positive_regulation of Trpv1 1 0.33 2.43 4.37
56 INT113223 POMC Regulation of MC1R 6 0.68 0.39 4.24
57 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23
58 INT1313 Pomc Positive_regulation of Prl 7 0.35 0 4.19
59 INT161109 Avp Positive_regulation of Chkb 1 0.12 0.18 4.19
60 INT11613 Cck Positive_regulation of Localization of Oxt 3 0.53 0 4.17
61 INT182194 Binding of IL8 and CXCR2 10 0.56 7.14 4.16
62 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15
63 INT64756 oh Negative_regulation of Gpi1 1 0.03 0 4.09
64 INT16221 Ghrh Positive_regulation of Gh 8 0.21 1.89 4.08
65 INT29240 Binding of POMC and YY1 5 0.40 0.17 4.06
66 INT34220 Binding of POMC and Oprl1 4 0.01 0.25 4.05
67 INT11248 Gh Positive_regulation of Ghrh 2 0.26 0.09 4.04
68 INT13969 Binding of Calca and Sst 3 0.32 0.6 4.02
69 INT95730 Binding of CP and SPINK1 2 0.19 5.65 4.02
70 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01
71 INT73539 Binding of Ngf and Ngfr 5 0.45 3.99 4
72 INT138961 Dbi Positive_regulation of Chkb 1 0.00 3.05 3.99
73 INT138959 Dbi Positive_regulation of Penk 1 0.01 3.05 3.99
74 INT20456 Binding of Pomc and Penk 9 0.41 0.26 3.93
75 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92
76 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91
77 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
78 INT69032 IL18 Positive_regulation of IFNA1 12 0.23 7.87 3.83
79 INT143946 Binding of Pebp1 and Mastl 1 0.00 2.04 3.82
80 INT11252 Cck Positive_regulation of Fos 6 0.78 0 3.79
81 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79
82 INT180813 Ngf Positive_regulation of Sorbs1 1 0.04 2.09 3.79
83 INT69938 Cck Positive_regulation of Localization of Abat 2 0.29 0 3.78
84 INT141254 Ngf Regulation of Transcription of Trpv1 1 0.53 1.37 3.74
85 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
86 INT107331 Binding of PPBP and Adarb1 1 0.01 0 3.67
87 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66
88 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65
89 INT15984 Binding of Avp and Oxt 11 0.32 1.33 3.64
90 INT140011 Avp Positive_regulation of Dbi 2 0.07 0.93 3.61
91 INT29837 Gnrh1 Positive_regulation of LH 6 0.67 0 3.53
92 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
93 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52
94 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
95 INT24710 Binding of Calca and SUB1P1 1 0.01 2.09 3.48
96 INT180984 IRF6 Positive_regulation of Localization of IL8 7 0.11 2.13 3.47
97 INT73071 Binding of Cpe and Insrr 3 0.01 0.33 3.38
98 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35
99 INT7436 CFP Positive_regulation of Binding of POMC 1 0.02 0.18 3.35
100 INT215943 Binding of Mmp14 and Timp2 1 0.21 1.59 3.33
101 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27
102 INT108471 Binding of CALCA and PNOC 1 0.29 0.64 3.25
103 INT354207 Igfbp7 Positive_regulation of Accn3 1 0.52 6.55 3.24
104 INT69823 Binding of GHR and RYBP 1 0.01 0 3.23
105 INT7190 Syt17 Positive_regulation of Ctsb 1 0.16 0 3.23
106 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
107 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
108 INT7193 Abl2 Positive_regulation of Ctsb 1 0.21 0 3.21
109 INT13729 GHRH Positive_regulation of Localization of GH1 13 0.62 0.59 3.2
110 INT18793 Crh Regulation of Localization of Penk 1 0.59 0 3.2
111 INT270949 Binding of Slc6a3 and Cpe 1 0.28 0.25 3.19
112 INT34294 Penk Positive_regulation of Localization of Crh 1 0.16 0.43 3.19
113 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17
114 INT91271 Mtr Regulation of Gene_expression of Il6 1 0.20 0 3.17
115 INT149492 PNOC Negative_regulation of Gene_expression of CCL2 1 0.15 0.68 3.17
116 INT29657 Binding of Calca and Calcb 1 0.26 0 3.16
117 INT17456 Binding of CSF2 and POMC 3 0.32 4.06 3.15
118 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
119 INT6076 Negative_regulation of Pomc Positive_regulation of Penk 3 0.31 0 3.14
120 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11
121 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11
122 INT30424 Penk Regulation of Localization of Sst 1 0.20 0 3.1
123 INT81708 POMC Regulation of Gene_expression of ITGAM 1 0.53 0.72 3.1
124 INT1151 Binding of CCK and GAST 7 0.49 0.73 3.08
125 INT208572 Binding of IL8 and CXCR1 6 0.33 5.2 3.08
126 INT122776 Gdnf Positive_regulation of Gene_expression of Trpv1 2 0.67 2.13 3.06
127 INT36535 PRSS1 Positive_regulation of Regulation of PENK 1 0.23 0.54 3.06
128 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
129 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
130 INT28235 Binding of Cck and Gast 5 0.38 0.73 2.96
131 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95
132 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
133 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
134 INT100835 Binding of Calca and Akap12 1 0.07 0.41 2.92
135 INT166592 Binding of CALCA and RAMP1 2 0.35 0.33 2.91
136 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
137 INT42728 Binding of PRLR and Cpe 1 0.00 0 2.91
138 INT150632 Ea1 Negative_regulation of Mpo 1 0.17 1.55 2.9
139 INT134212 CRH Regulation of Localization of POMC 1 0.47 2.89 2.9
140 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9
141 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
142 INT69937 Cck Positive_regulation of Abat 2 0.31 0 2.88
143 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
144 INT140014 Avp Negative_regulation of Chkb 1 0.04 1.58 2.86
145 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
146 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
147 INT194409 Binding of CALCA and IGKV1D-8 1 0.15 0 2.84
148 INT32656 Pomc Positive_regulation of Rbm39 1 0.08 0.42 2.84
149 INT130085 Crp Positive_regulation of Gene_expression of Vcam1 1 0.23 4.34 2.84
150 INT107723 POMC Positive_regulation of MC1R 7 0.68 0.71 2.82
151 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81
152 INT220062 Binding of NGF and TNFRSF1B 1 0.10 2.21 2.81
153 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
154 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79
155 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
156 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78
157 INT91649 Binding of Lbp and SPECC1 1 0.12 2.88 2.78
158 INT23280 PRSS1 Positive_regulation of Penk 1 0.05 1.53 2.74
159 INT69030 IL18 Positive_regulation of IL12A 3 0.31 5.57 2.72
160 INT226118 Ghrl Regulation of Prkag1 1 0.08 0.72 2.72
161 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
162 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
163 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
164 INT30133 Binding of Cck and Penk 1 0.27 2.49 2.71
165 INT69057 H2-M3 Regulation of Klkb1 1 0.00 0.42 2.71
166 INT318474 Positive_regulation of OPRM1 Positive_regulation of Localization of CA2 1 0.17 0.55 2.7
167 INT151381 St8sia1 Positive_regulation of Cck 1 0.19 0.45 2.7
168 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
169 INT87267 Binding of BMP8B and KRIT1 1 0.06 0.16 2.69
170 INT278948 LEP Positive_regulation of Gene_expression of PTGER2 1 0.09 4.04 2.69
171 INT62450 Il2 Positive_regulation of Localization of Crh 1 0.43 0.59 2.64
172 INT7888 Oprl1 Regulation of Localization of Avp 4 0.49 0.25 2.63
173 INT152113 Binding of NTSR1 and Ngf 3 0.33 2.09 2.62
174 INT212505 Binding of pr and Lbp 1 0.01 4.26 2.62
175 INT30345 Pomc Regulation of Localization of Penk 3 0.31 0 2.61
176 INT53648 Acot1 Positive_regulation of Localization of Calca 2 0.23 0 2.61
177 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
178 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 1 0.06 0.5 2.6
179 INT189490 Binding of Ccr3 and Ccl5 1 0.33 8.54 2.6
180 INT67663 Ins1 Positive_regulation of Ntrk2 1 0.00 0.19 2.59
181 INT29446 Crh Positive_regulation of Localization of POMC 8 0.38 1.87 2.58
182 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
183 INT111787 Cck Regulation of Gene_expression of Npr1 1 0.22 1.68 2.57
184 INT111789 Cck Regulation of Gene_expression of Penk 1 0.49 1.68 2.57
185 INT111786 Penk Regulation of Gene_expression of Cck 1 0.49 1.66 2.55
186 INT67905 Binding of Spn and Fosl1 1 0.24 2.1 2.54
187 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
188 INT26892 OGG1 Negative_regulation of Gene_expression of Gh1 1 0.12 0 2.53
189 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
190 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
191 INT107812 Nppa Positive_regulation of Localization of Sst 1 0.48 0.54 2.51
192 INT48526 Binding of Calca and Penk 1 0.24 1.03 2.51
193 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
194 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
195 INT107322 Positive_regulation of TRPV1 Positive_regulation of Localization of IL8 3 0.13 1.64 2.5
196 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5
197 INT314141 Binding of Tacr3 and SFTPA1 1 0.00 3.02 2.48
198 INT20411 Ghrh Positive_regulation of Gh1 6 0.56 0.62 2.47
199 INT130284 Ins1 Negative_regulation of Gene_expression of Npy 1 0.32 0.1 2.47
200 INT149494 PNOC Negative_regulation of Gene_expression of CCL5 1 0.19 0.52 2.46

Single Events

The table below shows the top 100 pain related interactions that have been reported for extracellular space. They are ordered first by their pain relevance and then by number of times they were reported in extracellular space. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 2008 0.81 518.3 1408.65
2 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
3 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84
4 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08
5 INT443 Localization of POMC 1020 0.81 284.52 443.17
6 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
7 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04
8 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16
9 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38
10 INT287 Localization of Cck 518 0.81 86.84 364.04
11 INT439 Localization of Gnrh1 976 0.81 100.96 363.25
12 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83
13 INT876 Localization of Gh1 843 0.80 67.75 340.82
14 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
15 INT2649 Regulation of Calca 433 0.62 146.05 330.95
16 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
17 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56
18 INT477 Localization of Avp 813 0.81 131.58 300.4
19 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98
20 INT3579 Localization of Oxt 555 0.81 43.35 292.44
21 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
22 INT2365 Positive_regulation of Cck 354 0.70 87.8 277.41
23 INT6852 Localization of TNF 883 0.81 705.95 270.84
24 INT10832 Gene_expression of IL8 1050 0.78 698.72 270
25 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57
26 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
27 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
28 INT1893 Localization of Gh 1041 0.79 340.23 256.58
29 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
30 INT3948 Regulation of Cck 291 0.62 58.07 255.88
31 INT1005 Localization of Sst 385 0.81 26.31 244.56
32 INT738 Regulation of POMC 459 0.62 111.19 243.74
33 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92
34 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238
35 INT1562 Localization of Crh 499 0.81 126.74 236.68
36 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45
37 INT626 Localization of CALCA 289 0.81 125.39 221.15
38 INT1308 Localization of Pomc 457 0.81 66.83 217.5
39 INT6481 Binding of TNF 624 0.48 510.2 214.82
40 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
41 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08
42 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24
43 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
44 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
45 INT1652 Regulation of Pomc 387 0.62 61.01 186.51
46 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71
47 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
48 INT943 Negative_regulation of Cck 205 0.59 38.42 174.78
49 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09
50 INT438 Gene_expression of Crh 376 0.78 159.11 169.17
51 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77
52 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02
53 INT1114 Localization of Ins1 748 0.80 192.95 165.48
54 INT2366 Binding of Cck 192 0.48 30.64 163.46
55 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18
56 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63
57 INT21185 Binding of Ptprg 213 0.47 13.49 157.75
58 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07
59 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37
60 INT880 Positive_regulation of Localization of Gh1 304 0.70 14.79 150.23
61 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15
62 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57
63 INT6108 Gene_expression of Npy 292 0.78 110.65 148.21
64 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
65 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69
66 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64
67 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69
68 INT812 Localization of INS 1026 0.81 515.6 145.31
69 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2
70 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69
71 INT9660 Regulation of TNF 363 0.62 312.94 139.99
72 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7
73 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52
74 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47
75 INT2541 Binding of Calca 200 0.48 67.14 134.62
76 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87
77 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14
78 INT695 Binding of POMC 304 0.48 56.66 126.85
79 INT5008 Localization of Calca 204 0.81 80.35 125.16
80 INT252 Localization of GH1 529 0.80 227.4 122.05
81 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64
82 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28
83 INT1026 Binding of Lbp 207 0.48 150.96 119.16
84 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03
85 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75
86 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
87 INT7395 Localization of GNRH1 399 0.81 62.88 117.68
88 INT12339 Localization of IL8 437 0.81 251.87 117.39
89 INT1438 Localization of Pomc 360 0.81 101.26 116.47
90 INT4207 Regulation of Avp 267 0.62 63.72 115.33
91 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12
92 INT1530 Regulation of Gh 382 0.61 115.96 112.47
93 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06
94 INT7362 Gene_expression of Sst 185 0.78 41.73 111.37
95 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
96 INT5283 Positive_regulation of Npy 191 0.70 66.77 109.2
97 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84
98 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01
99 INT12082 Localization of IL6 365 0.81 241.78 105.78
100 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74
101 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
102 INT4742 Gene_expression of Tac1 177 0.78 69.99 102.66
103 INT1898 Regulation of Crh 220 0.62 61.33 102.64
104 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62
105 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35
106 INT5940 Negative_regulation of Avp 236 0.59 67.86 101.2
107 INT397 Localization of SST 232 0.81 58.05 101.19
108 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
109 INT2159 Regulation of Localization of Gnrh1 200 0.62 13.28 99.07
110 INT874 Positive_regulation of Gh1 244 0.70 27.17 97.98
111 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61
112 INT4822 Localization of Ca2 417 0.80 99.57 96.45
113 INT1004 Regulation of Sst 140 0.62 18.52 94.84
114 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35
115 INT2862 Positive_regulation of Localization of Cck 108 0.70 20.75 94.25
116 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89
117 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5
118 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84
119 INT2122 Negative_regulation of Localization of Gnrh1 226 0.59 26.92 92.04
120 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43
121 INT214 Localization of AVP 370 0.81 208.51 91.09
122 INT10166 Localization of Tnf 237 0.81 153.95 88.64
123 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6
124 INT7885 Positive_regulation of Localization of Oxt 160 0.70 14.36 87.7
125 INT1472 Positive_regulation of Ins1 349 0.69 146.2 86.36
126 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43
127 INT21793 Positive_regulation of Ngf 154 0.70 94.78 85.27
128 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03
129 INT875 Regulation of Localization of Gh1 166 0.62 12.87 84.97
130 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91
131 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02
132 INT4289 Positive_regulation of Localization of Gnrh1 202 0.70 12.3 84.01
133 INT2520 Negative_regulation of Ca2 271 0.57 72.13 83.71
134 INT4631 Positive_regulation of Sst 127 0.70 17.37 83.29
135 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08
136 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71
137 INT6107 Localization of Npy 180 0.81 26.76 81.67
138 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
139 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16
140 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53
141 INT2893 Localization of Oxt 219 0.80 28.96 79.43
142 INT3214 Localization of Ins1 527 0.80 196.9 79.26
143 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47
144 INT2155 Negative_regulation of Sst 111 0.59 16.58 77.74
145 INT4358 Positive_regulation of Localization of Avp 195 0.70 30.79 77.58
146 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19
147 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45
148 INT12001 Regulation of Ngf 97 0.62 54.64 76.25
149 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96
150 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76
151 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35
152 INT881 Negative_regulation of Localization of Gh1 164 0.58 15.1 75.28
153 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71
154 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57
155 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48
156 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
157 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42
158 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
159 INT7886 Regulation of Localization of Avp 146 0.62 14.53 72.99
160 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92
161 INT3034 Localization of Ngf 126 0.81 50.81 72.84
162 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4
163 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
164 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14
165 INT8962 Gene_expression of Cpe 110 0.71 39.67 71.67
166 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38
167 INT2055 Regulation of Gnrh1 185 0.62 23.65 71.26
168 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
169 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
170 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34
171 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
172 INT6849 Localization of IL1B 229 0.81 112.56 69.63
173 INT451 Regulation of Oxt 142 0.62 22.07 69.42
174 INT2123 Positive_regulation of Gnrh1 209 0.70 24.2 68.97
175 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66
176 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6
177 INT1988 Positive_regulation of Localization of Ins1 254 0.69 59.25 68.37
178 INT7344 Gene_expression of TAC1 132 0.75 35.48 68.26
179 INT7134 Localization of KNG1 127 0.79 65.73 67.97
180 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
181 INT19511 Localization of Il6 212 0.81 118.17 67.67
182 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41
183 INT462 Regulation of Pomc 157 0.62 41.67 67.27
184 INT7468 Negative_regulation of Localization of Oxt 109 0.59 9.46 66.79
185 INT9489 Gene_expression of SFTPA1 112 0.66 55.38 66.45
186 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
187 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73
188 INT5941 Gene_expression of Oxt 164 0.76 22.63 65.47
189 INT8347 Gene_expression of SST 181 0.78 104.59 65.45
190 INT13286 Gene_expression of Ca2 317 0.67 71.58 65.01
191 INT11807 Gene_expression of Il2 266 0.78 112 64.97
192 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86
193 INT11937 Localization of Il6 228 0.81 139.83 64.39
194 INT480 Negative_regulation of Localization of Avp 151 0.59 27.64 63.72
195 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6
196 INT9664 Binding of LBP 127 0.48 94.9 63.42
197 INT7280 Positive_regulation of Localization of Sst 97 0.70 5.64 63.37
198 INT2056 Negative_regulation of Gnrh1 175 0.59 33.43 63.32
199 INT46 Localization of Ren 233 0.81 46.15 62.44
200 INT10706 Regulation of Il6 150 0.62 93.23 62.34
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