GO:0005635

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Name nuclear envelope
Categary Component
Go Slim Yes
Go Link GO:0005635
Unique Molecular Interactions 888
Total Molecular Interactions 1184
Total Single Events 12782
Pain Genes Associated 91

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for nuclear envelope. They are ordered first by their pain relevance and then by number of times they were reported for nuclear envelope. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT98346 Negative_regulation of Binding of CPOX and PTGS1 1 0.10 2.91 6.54
2 INT73539 Binding of Ngf and Ngfr 5 0.45 3.99 4
3 INT48162 RIMS3 Regulation of Localization of LTC4S 1 0.10 2.14 3.25
4 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
5 INT229497 Binding of Vim and Ndel1 1 0.33 3.5 2.81
6 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63
7 INT37873 Pag1 Regulation of Nrm 2 0.04 1.1 2.41
8 INT81657 Binding of CPOX and PTGS1 5 0.15 1.9 2.37
9 INT89733 Binding of Calca and Nrm 1 0.31 0.71 2.09
10 INT142073 Binding of Helt and Nrm 1 0.00 0 1.74
11 INT167765 Prkca Positive_regulation of Sigmar1 1 0.41 0.63 1.74
12 INT149680 Binding of Parp1 and Oprm1 1 0.53 0 1.66
13 INT54601 Binding of Mtor and Ache 1 0.20 0.8 1.58
14 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
15 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48
16 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45
17 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45
18 INT28992 Tmpo Positive_regulation of Pomc 1 0.36 3.18 1.41
19 INT229496 Binding of Ndel1 and Gopc 1 0.08 2.05 1.36
20 INT132412 Negative_regulation of Ngf Negative_regulation of Ptgs1 1 0.01 0.81 1.31
21 INT136200 Binding of Penk and NUP37 1 0.04 0 1.28
22 INT280480 Binding of Bdnf and Ngfr 5 0.25 3.14 1.27
23 INT105295 WAS Regulation of PTGS1 1 0.02 0.13 1.27
24 INT110542 SIGMAR1 Regulation of OPRM1 1 0.04 0.33 1.25
25 INT110543 SIGMAR1 Regulation of Gene_expression of OPRM1 1 0.04 0.33 1.25
26 INT121000 Binding of PAG1 and Nrm 1 0.13 0.67 1.25
27 INT13603 Binding of NCF4 and Nrm 2 0.40 0.21 1.22
28 INT103031 Calca Positive_regulation of Ptgs1 2 0.46 0.98 1.22
29 INT203168 PTGER2 Negative_regulation of Gene_expression of ALOX5AP 1 0.03 2.4 1.18
30 INT189017 Binding of Pax3 and Lmna 1 0.14 0.42 1.16
31 INT76256 Binding of Slc6a3 and Sigmar1 1 0.20 0 1.16
32 INT35399 Binding of Alox5 and Mthfs 1 0.01 0 1.14
33 INT256041 Binding of Ngfr and Ntrk1 3 0.14 0.9 1.13
34 INT68160 Alox5 Positive_regulation of Positive_regulation of Pla2g1b 1 0.03 0.64 1.13
35 INT110671 Binding of Cnr1 and Alox5 1 0.07 0.2 1.13
36 INT68164 Mthfs Positive_regulation of Positive_regulation of Alox5 1 0.00 0.64 1.13
37 INT68167 Alox5 Positive_regulation of Positive_regulation of Mthfs 1 0.00 0.64 1.13
38 INT110669 Binding of Alox5 and Trpv1 1 0.07 0.2 1.13
39 INT68157 Alox5 Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.13
40 INT68156 Pla2g1b Positive_regulation of Positive_regulation of Alox5 1 0.03 0.64 1.13
41 INT68165 Alox5 Positive_regulation of Pdpk1 1 0.01 0.63 1.12
42 INT82024 Binding of Ngfr and Ngf 2 0.33 1.48 1.05
43 INT312097 ELANE Regulation of ALOX5 1 0.08 1.75 1.05
44 INT76001 Ngf Positive_regulation of Ngfr 1 0.16 0.93 1.05
45 INT126401 ITIH4 Positive_regulation of Gene_expression of Ptgs2 1 0.00 1.05 1.04
46 INT151218 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Akt1 1 0.00 0.26 1.03
47 INT242642 Binding of BDNF and Ngfr 2 0.21 1.38 1.01
48 INT140653 IGF1 Negative_regulation of Protein_catabolism of PARP1 1 0.32 0.63 0.98
49 INT60213 Binding of Ptgs1 and Ptgs2 2 0.37 0.5 0.97
50 INT253836 Cck Regulation of DST 1 0.03 0.42 0.95
51 INT61037 Och Positive_regulation of Ptgs1 1 0.00 0 0.95
52 INT203162 PTGER2 Regulation of Gene_expression of ALOX5AP 1 0.04 1.47 0.94
53 INT107335 Pdpk1 Positive_regulation of Regulation of Sigmar1 1 0.02 0 0.93
54 INT185417 Binding of ALOX5 and PLA2G2A 4 0.16 3.13 0.9
55 INT119100 Positive_regulation of F2rl1 Positive_regulation of Positive_regulation of Ptgs1 1 0.03 0.56 0.9
56 INT167767 Prkcz Positive_regulation of Phosphorylation of Sigmar1 1 0.04 0.23 0.9
57 INT167766 Prkcz Positive_regulation of Positive_regulation of Sigmar1 1 0.04 0.23 0.9
58 INT167771 Prkca Positive_regulation of Phosphorylation of Sigmar1 1 0.38 0.23 0.89
59 INT57746 Il1 Regulation of Gene_expression of Ltc4s 1 0.36 0.33 0.88
60 INT52195 Sigmar1 Positive_regulation of Positive_regulation of Grin1 1 0.15 0 0.87
61 INT251704 Ache Regulation of Gene_expression of Acot1 1 0.08 1.68 0.87
62 INT161048 Nrm Positive_regulation of Prdm4 1 0.56 1.47 0.86
63 INT323698 Gene_expression of MIR146A Regulation of FAF1 1 0.16 1.82 0.86
64 INT116559 Olr1627 Negative_regulation of Regulation of Ptgs2 1 0.01 1.52 0.86
65 INT73538 Ngf Positive_regulation of Ngfr 2 0.41 1.05 0.85
66 INT110315 Negative_regulation of ALOX5 Negative_regulation of Gene_expression of TNF 1 0.47 0.74 0.85
67 INT340294 Ea1 Positive_regulation of Sirt1 1 0.06 0.53 0.83
68 INT113250 Olr1259 Negative_regulation of Ache 1 0.01 0.38 0.83
69 INT352201 Negative_regulation of ALOX5 Negative_regulation of Cpox 1 0.02 0.89 0.81
70 INT62176 Binding of PTGS2 and Ptgs1 2 0.00 0.69 0.79
71 INT200094 Negative_regulation of Jun Negative_regulation of Gene_expression of Ptgs2 1 0.01 2.87 0.78
72 INT203164 PTGER2 Regulation of ALOX5 1 0.00 0.9 0.78
73 INT203171 PTGER2 Negative_regulation of ALOX5 1 0.01 0.89 0.77
74 INT167770 Sigmar1 Positive_regulation of Prkcz 1 0.04 0.34 0.77
75 INT167768 Regulation of Sigmar1 Positive_regulation of Prkcz 1 0.02 0.34 0.77
76 INT46246 Tpsg1 Regulation of Ache 1 0.15 0.06 0.76
77 INT46247 Tpsg1 Regulation of Binding of Ache 1 0.15 0.06 0.76
78 INT128861 LBR Positive_regulation of Positive_regulation of OPRM1 1 0.19 0.36 0.75
79 INT106691 Ngf Positive_regulation of SIGMAR1 1 0.04 0 0.74
80 INT18447 Binding of Ache and Chat 2 0.33 0.33 0.73
81 INT312101 ELANE Regulation of ALOX5AP 1 0.21 1.11 0.73
82 INT119314 Ptgs1 Regulation of Gene_expression of Ptger2 1 0.01 0.6 0.73
83 INT213726 Binding of Ngfr and Ntrk1 1 0.14 0.96 0.72
84 INT43663 Binding of Chrna7 and Rac2 1 0.01 0 0.72
85 INT289333 Binding of Ngfr and Rtn4r 1 0.03 2.35 0.72
86 INT289332 Binding of Ngfr and Lingo1 1 0.04 2.36 0.72
87 INT37874 Positive_regulation of Pag1 Regulation of Nrm 1 0.04 0.59 0.71
88 INT159569 Negative_regulation of Alox5 Negative_regulation of Gene_expression of Fos 1 0.37 0.4 0.7
89 INT65426 Sigmar1 Regulation of Gpi1 1 0.21 0 0.7
90 INT82021 Negative_regulation of Binding of Ngfr and Ngf 1 0.29 0.32 0.69
91 INT114735 Mtx1 Regulation of Ptgs1 1 0.01 0.31 0.69
92 INT289357 Ngfr Positive_regulation of Akt1 1 0.03 3.1 0.66
93 INT149684 Negative_regulation of Parp1 Positive_regulation of Oprm1 1 0.51 0 0.65
94 INT46892 Positive_regulation of Binding of Pag1 and Nrm 1 0.01 0.61 0.63
95 INT46891 Binding of Pag1 and Nrm 1 0.01 0.61 0.63
96 INT149681 Parp1 Regulation of Transcription of Oprm1 1 0.67 0 0.63
97 INT38905 Ptgfr Regulation of Ptgds 1 0.20 0 0.63
98 INT96765 LBR Positive_regulation of Gene_expression of TP53INP2 1 0.11 0.5 0.62
99 INT101320 Negative_regulation of Ptgs1 Positive_regulation of Ptgs2 1 0.03 0.2 0.62
100 INT55672 Ptgs1 Positive_regulation of Gene_expression of Ik 1 0.03 0.75 0.61
101 INT164286 Alox5ap Positive_regulation of Cysltr2 1 0.19 1.11 0.61
102 INT164285 Ltc4s Positive_regulation of Cysltr2 1 0.20 1.11 0.61
103 INT149682 Parp1 Negative_regulation of Oprm1 1 0.47 0 0.6
104 INT164283 Ltb4r Positive_regulation of Ltc4s 1 0.37 1.1 0.6
105 INT55919 Binding of Sigmar1 and Ap2s1 1 0.02 0.84 0.6
106 INT164284 Ltb4r Positive_regulation of Alox5ap 1 0.34 1.1 0.6
107 INT270100 Negative_regulation of Binding of ALOX5 and PLA2G2A 1 0.01 0.51 0.59
108 INT89012 DST Positive_regulation of Insr 1 0.01 0.86 0.59
109 INT137247 Slc6a14 Negative_regulation of Ptgs2 2 0.19 1.38 0.58
110 INT35398 Fnd3c2 Negative_regulation of Binding of Alox5 1 0.00 0 0.58
111 INT137248 Slc6a14 Negative_regulation of Gene_expression of Ptgs2 1 0.19 1.32 0.58
112 INT149683 Parp1 Negative_regulation of Transcription of Oprm1 1 0.47 0 0.58
113 INT335432 Ltc4s Regulation of Cysltr2 1 0.11 0.38 0.58
114 INT335436 Ltc4s Regulation of Gene_expression of Cysltr2 1 0.18 0.38 0.58
115 INT2685 S100A6 Positive_regulation of Regulation of Thra 1 0.47 0.09 0.58
116 INT2684 S100A6 Regulation of Regulation of Thra 1 0.45 0.09 0.58
117 INT73707 Ngf Regulation of Scgb1a1 1 0.25 0.61 0.58
118 INT134532 Grin2a Regulation of Ngfr 1 0.02 0 0.57
119 INT134528 Grin1 Regulation of Ngfr 1 0.03 0 0.57
120 INT134531 Gria1 Regulation of Ngfr 1 0.01 0 0.57
121 INT270102 ALOX5 Negative_regulation of PLA2G2A 1 0.01 0.49 0.57
122 INT133913 Faf1 Negative_regulation of Regulation of TRPV1 1 0.18 0.16 0.56
123 INT95895 Sigmar1 Regulation of Positive_regulation of Npy 1 0.18 0 0.55
124 INT97635 ABCF1 Positive_regulation of Localization of CCR1 1 0.05 0.51 0.55
125 INT176371 LBR Positive_regulation of IL12A 1 0.04 1.22 0.55
126 INT253835 Binding of DST and Fos 1 0.02 0 0.55
127 INT133914 Binding of TRPV1 and Faf1 1 0.20 0.17 0.55
128 INT176367 LBR Positive_regulation of IFNA1 1 0.02 1.22 0.55
129 INT155254 Col4a4 Regulation of Rtn4 1 0.00 0 0.54
130 INT76200 CASP1 Positive_regulation of Gene_expression of PTGS1 1 0.05 0.16 0.54
131 INT125086 LPA Positive_regulation of Rtn4 1 0.00 0.36 0.54
132 INT161251 Ptgs2 Regulation of Mapk14 1 0.16 0.82 0.54
133 INT18115 Binding of NPC1 and Oprd1 1 0.11 0 0.54
134 INT76002 Ngf Positive_regulation of Ngfr 1 0.05 0.48 0.53
135 INT245558 Runx3 Regulation of Ngfr 1 0.06 1 0.53
136 INT21372 Binding of pcp and Sigmar1 1 0.01 0 0.53
137 INT69882 Ptger2 Positive_regulation of Gene_expression of Ptgs2 1 0.19 0.6 0.52
138 INT54599 Positive_regulation of Ascla2 Positive_regulation of Nrm 1 0.00 0.14 0.52
139 INT151220 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Prkca 1 0.00 0.13 0.51
140 INT151222 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Adrbk1 1 0.00 0.13 0.51
141 INT151223 Negative_regulation of SIGMAR1 Negative_regulation of Adrbk1 1 0.00 0.13 0.51
142 INT97636 ABCF1 Positive_regulation of Localization of CXCR1 1 0.35 0.45 0.51
143 INT105849 Il1b Positive_regulation of Positive_regulation of Ptgs1 1 0.07 0.38 0.51
144 INT151219 Negative_regulation of SIGMAR1 Negative_regulation of Prkca 1 0.00 0.13 0.51
145 INT97634 ABCF1 Positive_regulation of Localization of CCL16 1 0.11 0.44 0.51
146 INT151221 Negative_regulation of SIGMAR1 Negative_regulation of Akt1 1 0.00 0.13 0.51
147 INT78590 Nos2 Positive_regulation of PTGS1 2 0.00 0.85 0.5
148 INT161227 Binding of Ngfr and Tnf 1 0.06 0.41 0.49
149 INT155921 PARP1 Positive_regulation of Gene_expression of IL6 1 0.49 0.44 0.48
150 INT153330 Binding of PTGER3 and Cm9 1 0.36 0.15 0.48
151 INT348402 LPA Positive_regulation of Gene_expression of Ptgs2 1 0.01 0.62 0.48
152 INT131809 Nfkb1 Positive_regulation of Gene_expression of Ptgs1 1 0.12 0.73 0.48
153 INT129551 Sag Negative_regulation of Gene_expression of Ptgs1 1 0.08 0.88 0.48
154 INT48102 Positive_regulation of LBR Positive_regulation of Positive_regulation of OR7A5 1 0.21 0 0.48
155 INT251163 Gene_expression of Alox5 Positive_regulation of Trpv1 1 0.02 0.11 0.48
156 INT312112 ELANE Regulation of Transcription of ALOX5 1 0.09 0.82 0.47
157 INT340296 Ea1 Regulation of Gene_expression of Sirt1 1 0.08 0.15 0.46
158 INT176366 LBR Regulation of IFNA1 1 0.04 0.91 0.46
159 INT103026 Ptgis Positive_regulation of Ptgs1 1 0.02 0.42 0.46
160 INT110476 EDN1 Positive_regulation of Localization of PRKCZ 1 0.25 0.07 0.46
161 INT103029 Calca Positive_regulation of Positive_regulation of Ptgs1 1 0.12 0.41 0.46
162 INT17774 Alb Negative_regulation of Dnase1 1 0.02 0 0.46
163 INT99160 Binding of Mpo and Nrm 1 0.38 0.92 0.45
164 INT193219 Binding of LTC4S and CYSLTR2 2 0.28 2.2 0.44
165 INT69163 Tlr4 Positive_regulation of Ptgs1 1 0.02 0.08 0.44
166 INT193217 Binding of PTGER2 and PTGER3 2 0.10 1.31 0.43
167 INT12453 Sigmar1 Regulation of Gene_expression of Penk 2 0.35 0 0.43
168 INT120295 Ngf Positive_regulation of Positive_regulation of Ngfr 1 0.47 0.22 0.43
169 INT158267 Olr1745 Negative_regulation of Alox5 1 0.05 0.94 0.43
170 INT229507 Binding of Nefl and Ndel1 1 0.09 2.01 0.43
171 INT53470 Acsm3 Regulation of Ptgs1 1 0.15 0 0.42
172 INT121378 Fancl Positive_regulation of MIF 1 0.01 0.92 0.42
173 INT53469 Negative_regulation of Acsm3 Regulation of Ptgs1 1 0.24 0 0.42
174 INT244421 Binding of DST and Ctss 1 0.02 0.42 0.41
175 INT209231 Tg(Ngf)47Kma Regulation of Tyro3 1 0.03 0 0.41
176 INT53471 Binding of Ptgs1 and Acsm3 1 0.17 0 0.41
177 INT299789 IL4 Negative_regulation of Gene_expression of RAE1 1 0.00 0.84 0.41
178 INT91107 Positive_regulation of Ptgs1 Positive_regulation of Localization of Crh 1 0.00 0.56 0.41
179 INT203163 LTB4R Regulation of Gene_expression of ALOX5 1 0.00 0.98 0.41
180 INT67633 Binding of DST and Gabrd 1 0.03 0 0.41
181 INT159571 Trpv1 Positive_regulation of Gene_expression of Alox5 1 0.37 0.58 0.4
182 INT312123 ELANE Positive_regulation of ALOX5 1 0.09 0.74 0.4
183 INT200096 Negative_regulation of Il1a Negative_regulation of Gene_expression of Ptgs2 1 0.00 1.45 0.39
184 INT176361 Positive_regulation of LBR Positive_regulation of Gene_expression of IL18 1 0.10 0.84 0.39
185 INT203167 Gene_expression of PTGER2 Positive_regulation of Gene_expression of ALOX5AP 1 0.03 0.67 0.38
186 INT50553 Negative_regulation of Ptgs1 Negative_regulation of Gene_expression of Tbxa2r 1 0.02 1.37 0.38
187 INT73537 Ntf3 Positive_regulation of Ngfr 1 0.21 0.1 0.38
188 INT175016 Binding of REN and S100A6 2 0.11 1.13 0.37
189 INT28991 Tmpo Positive_regulation of Gene_expression of Pomc 1 0.34 0.82 0.37
190 INT158355 Cacna1a Regulation of Alox5 1 0.01 0.7 0.37
191 INT73536 Ngf Regulation of Ngfr 1 0.22 0.08 0.37
192 INT74244 Ptgs1 Regulation of Positive_regulation of Penk 1 0.09 0.19 0.37
193 INT224584 Binding of IL1RN and SIGMAR1 1 0.00 0.73 0.36
194 INT6121 Gmcl1 Regulation of Gene_expression of Penk 1 0.03 0 0.36
195 INT93694 Binding of Hspa8 and Ptgs1 1 0.30 0.79 0.36
196 INT312102 Binding of ALOX5 and ALOX5AP 1 0.10 0.65 0.36
197 INT99159 Nrm Positive_regulation of Mpo 1 0.44 0.85 0.36
198 INT241072 Tpr Positive_regulation of Regulation of Oprm1 1 0.01 0.08 0.36
199 INT167045 TRPA1 Regulation of PTGS1 1 0.19 0.1 0.35
200 INT194865 Binding of SIGMAR1 and Positive_regulation of IL1B 1 0.01 0.62 0.35

Single Events

The table below shows the top 100 pain related interactions that have been reported for nuclear envelope. They are ordered first by their pain relevance and then by number of times they were reported in nuclear envelope. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26
2 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6
3 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58
4 INT940 Negative_regulation of Ptgs1 219 0.59 104.34 95.97
5 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4
6 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08
7 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5
8 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73
9 INT5759 Positive_regulation of Ptgs1 127 0.69 53.45 53.04
10 INT1715 Positive_regulation of Nrm 51 0.70 24 47.53
11 INT8465 Regulation of Ptgs1 100 0.57 36.03 44.41
12 INT5418 Negative_regulation of Alox5 108 0.57 42.09 31.17
13 INT1079 Positive_regulation of Ache 104 0.70 23.52 30.28
14 INT52690 Positive_regulation of Ptgs2 65 0.68 39.51 30.02
15 INT9053 Negative_regulation of ALOX5 97 0.58 40.34 29.94
16 INT651 Positive_regulation of PTGS1 93 0.69 37.27 29.18
17 INT2389 Regulation of PTGS1 86 0.61 31.23 28.95
18 INT55908 Gene_expression of Ngfr 74 0.78 34.46 28.8
19 INT5923 Negative_regulation of Rtn4 50 0.36 24.19 27.2
20 INT2569 Gene_expression of Ache 120 0.78 26.29 26.89
21 INT276 Regulation of Ache 83 0.62 16.75 25.99
22 INT9886 Gene_expression of Ptgs1 92 0.77 40.66 25.31
23 INT21503 Binding of Ptgs1 45 0.48 15.6 22.29
24 INT41230 Gene_expression of Nrm 16 0.67 6.37 21.67
25 INT52693 Positive_regulation of Gene_expression of Ptgs2 57 0.70 25.51 21.18
26 INT45840 Positive_regulation of Gene_expression of Ptgs1 35 0.50 16.07 20.49
27 INT46016 Gene_expression of Ngfr 69 0.77 41.22 19.8
28 INT56239 Positive_regulation of Rtn4 20 0.26 14.05 18.8
29 INT17442 Gene_expression of ALOX5 110 0.75 51.55 18.29
30 INT5922 Gene_expression of Rtn4 27 0.48 12.7 17.86
31 INT19071 Localization of Ache 66 0.81 5.1 16.27
32 INT9197 Binding of PTGS1 44 0.48 18.48 16.26
33 INT1752 Negative_regulation of Ache 109 0.59 42.05 15.73
34 INT12837 Binding of SIGMAR1 57 0.48 5.31 15.49
35 INT195414 Gene_expression of ALOX5AP 65 0.72 31.22 15.25
36 INT53080 Positive_regulation of Ptgs1 42 0.42 23.58 14.37
37 INT23344 Gene_expression of Alox5 60 0.75 28.2 13.82
38 INT7997 Gene_expression of Ltc4s 51 0.76 34.28 13.8
39 INT53070 Regulation of Rtn4 15 0.22 9.35 13.77
40 INT20715 Binding of Sigmar1 45 0.48 4.03 13.17
41 INT3770 Negative_regulation of Nrm 13 0.43 3.55 12.83
42 INT1663 Regulation of Nrm 12 0.55 2.73 12.73
43 INT39244 Gene_expression of TMPO 137 0.77 14.55 11.83
44 INT12992 Negative_regulation of Gene_expression of Ptgs1 33 0.42 20.47 11.77
45 INT66038 Positive_regulation of Ngfr 32 0.69 26.07 11.75
46 INT20457 Regulation of Ptgs1 23 0.48 11.63 11.56
47 INT787 Localization of Ptgs1 31 0.80 12.36 11.55
48 INT13338 Regulation of Sigmar1 22 0.57 2.91 11.35
49 INT93129 Negative_regulation of KCNH2 42 0.54 9.63 10.85
50 INT52689 Regulation of Ptgs2 27 0.60 12.76 10.6
51 INT1252 Binding of Ache 46 0.48 9.94 10.25
52 INT17421 Negative_regulation of Alox5 41 0.57 15.23 10.05
53 INT85535 Negative_regulation of Gene_expression of Ptgs2 27 0.51 16.04 10.01
54 INT4808 Gene_expression of LTC4S 37 0.73 18.36 9.62
55 INT67101 Gene_expression of DST 47 0.54 25.92 9.59
56 INT37896 Positive_regulation of Gene_expression of PTGS1 37 0.67 17.28 9.27
57 INT12991 Negative_regulation of Gene_expression of PTGS1 28 0.41 13.39 8.9
58 INT23264 Negative_regulation of Positive_regulation of Ptgs1 16 0.39 8.47 8.9
59 INT9889 Gene_expression of Alox5 34 0.63 20.83 8.85
60 INT49866 Negative_regulation of Parp1 53 0.58 35.37 8.84
61 INT52442 Binding of Ptgs1 16 0.35 9.05 8.78
62 INT113845 Protein_catabolism of PARP1 54 0.88 43.86 8.77
63 INT6573 Regulation of Negative_regulation of Ptgs1 19 0.45 6.16 8.71
64 INT123813 Positive_regulation of Parp1 74 0.70 65.36 8.56
65 INT75921 Negative_regulation of Ngfr 13 0.59 8.58 8.35
66 INT48310 Binding of Ngfr 25 0.48 9.72 8.16
67 INT126583 Positive_regulation of PARP1 50 0.68 41.44 7.78
68 INT60148 Regulation of Sigmar1 20 0.43 7.23 7.76
69 INT20234 Regulation of Gene_expression of Ptgs1 11 0.44 6.55 7.72
70 INT4807 Localization of LTC4S 23 0.58 6.89 7.59
71 INT52688 Transcription of Ptgs2 16 0.69 8.31 7.52
72 INT61542 Positive_regulation of Ngfr 15 0.70 6.35 7.34
73 INT49751 Negative_regulation of Positive_regulation of PTGS1 12 0.45 4.73 7.23
74 INT39242 Negative_regulation of TMPO 29 0.58 5.15 7.04
75 INT12838 Gene_expression of SIGMAR1 30 0.78 3.52 6.81
76 INT78713 Negative_regulation of Ngfr 9 0.54 7.07 6.73
77 INT38644 Positive_regulation of DST 30 0.53 12.48 6.59
78 INT118151 Positive_regulation of Prkcz 5 0.12 2.35 6.41
79 INT25130 Positive_regulation of Negative_regulation of Ptgs1 14 0.50 5.07 6.29
80 INT86600 Gene_expression of KCNH2 37 0.78 14.88 6.14
81 INT17370 Negative_regulation of Negative_regulation of Ptgs1 16 0.22 6.5 6.12
82 INT78955 Regulation of Gene_expression of Ptgs2 12 0.62 7.22 6.02
83 INT48004 Positive_regulation of Negative_regulation of PTGS1 12 0.49 4.07 5.87
84 INT25242 Positive_regulation of Sigmar1 17 0.66 3.93 5.65
85 INT107619 Gene_expression of PTGER3 42 0.75 15 5.61
86 INT55917 Binding of Sigmar1 26 0.45 12.65 5.58
87 INT4613 Positive_regulation of Sirt1 32 0.67 18.19 5.53
88 INT7996 Gene_expression of Ptgds 18 0.64 6.47 5.51
89 INT28164 Regulation of ALOX5 25 0.60 12.76 5.47
90 INT50491 Regulation of Gene_expression of PTGS1 17 0.47 6 5.4
91 INT28165 Positive_regulation of ALOX5 38 0.47 10.8 5.37
92 INT5978 Positive_regulation of SIGMAR1 13 0.42 0.72 5.35
93 INT19072 Regulation of Gene_expression of Ache 14 0.62 2.74 5.29
94 INT140142 Positive_regulation of Sigmar1 17 0.63 3.78 5.26
95 INT39256 Localization of PTGS1 17 0.74 6.62 5.1
96 INT83728 Localization of TMPO 42 0.46 0.46 5.06
97 INT6577 Regulation of Alox5 18 0.47 9.19 5.06
98 INT10606 Localization of Ltc4s 16 0.75 10.14 5.05
99 INT75546 Transcription of Rtn4 1 0.06 2.87 5.03
100 INT44745 Localization of Nrm 5 0.65 2.04 4.92
101 INT20059 Protein_catabolism of Ache 15 0.98 3.73 4.87
102 INT3476 Phosphorylation of Npc1 7 0.48 0 4.84
103 INT10605 Positive_regulation of Ltc4s 21 0.68 17.22 4.8
104 INT30355 Positive_regulation of Gene_expression of Alox5 10 0.67 14.61 4.69
105 INT240934 Gene_expression of Sirt1 24 0.75 18.77 4.68
106 INT15995 Positive_regulation of Alox5 18 0.49 3.94 4.63
107 INT1753 Gene_expression of Ache 38 0.78 15.31 4.58
108 INT62500 Transcription of Ptgs1 10 0.56 4.54 4.52
109 INT178751 Positive_regulation of TMPO 51 0.44 1.47 4.41
110 INT64711 Regulation of Ngfr 10 0.45 3.12 4.33
111 INT11946 Transcription of Ache 18 0.69 2.62 4.13
112 INT76227 Binding of NPC1 30 0.41 32.31 4.05
113 INT74365 Positive_regulation of Alox5 19 0.47 11.03 4.04
114 INT121170 Positive_regulation of Gene_expression of Ngfr 10 0.64 9.32 3.94
115 INT64668 Regulation of SIGMAR1 13 0.60 0.54 3.91
116 INT26368 Positive_regulation of S100A6 30 0.45 9.72 3.89
117 INT121171 Negative_regulation of Gene_expression of Ngfr 6 0.58 3.46 3.89
118 INT20743 Positive_regulation of Gene_expression of Ltc4s 13 0.60 12.3 3.86
119 INT55907 Binding of Ngfr 13 0.47 5.79 3.75
120 INT10992 Gene_expression of PARP1 32 0.76 22.22 3.74
121 INT11761 Negative_regulation of DST 13 0.42 7.66 3.65
122 INT44254 Regulation of Gene_expression of ALOX5 12 0.43 7.06 3.65
123 INT8778 Regulation of Ache 17 0.62 3.7 3.57
124 INT72290 Localization of Sigmar1 21 0.74 4.35 3.54
125 INT102076 Regulation of DST 15 0.22 10 3.5
126 INT61540 Negative_regulation of Gene_expression of Ngfr 11 0.59 6.36 3.43
127 INT114571 Gene_expression of Sigmar1 39 0.77 36.78 3.4
128 INT99348 Negative_regulation of PARP1 38 0.58 30.96 3.36
129 INT28009 Positive_regulation of Gene_expression of Ache 15 0.70 5.46 3.26
130 INT16159 Regulation of Ltc4s 11 0.38 2.52 3.21
131 INT10476 Binding of ALOX5 26 0.36 7.69 3.2
132 INT8777 Positive_regulation of Ache 25 0.68 7.77 3.18
133 INT156676 Gene_expression of Rtn4 14 0.65 5.78 3.16
134 INT155091 Localization of PARP1 15 0.63 13.34 3.15
135 INT195415 Regulation of Gene_expression of ALOX5AP 10 0.45 6.43 3.13
136 INT52694 Negative_regulation of Positive_regulation of Ptgs2 9 0.43 4.72 3.11
137 INT77615 Positive_regulation of Negative_regulation of Ptgs1 6 0.50 1.55 3.11
138 INT35448 Negative_regulation of Gene_expression of ALOX5 11 0.57 5.28 3.03
139 INT123815 Gene_expression of Parp1 42 0.67 27.82 3.02
140 INT107677 Positive_regulation of Parp1 7 0.45 9.77 3
141 INT4811 Positive_regulation of Gene_expression of LTC4S 5 0.65 3.29 2.92
142 INT22069 Positive_regulation of Localization of Ache 9 0.70 0.61 2.9
143 INT200833 Gene_expression of Ndel1 2 0.73 5.56 2.9
144 INT118156 Binding of Prkcz 2 0.08 2.68 2.89
145 INT90402 Positive_regulation of Gene_expression of Ptgs1 13 0.31 4.83 2.88
146 INT107674 Negative_regulation of Parp1 7 0.27 8.91 2.88
147 INT76342 Positive_regulation of Gene_expression of Alox5 9 0.56 5.29 2.87
148 INT48106 Positive_regulation of LBR 11 0.49 5.14 2.86
149 INT17769 Positive_regulation of Dnase1 5 0.69 4.21 2.86
150 INT195421 Positive_regulation of Gene_expression of ALOX5AP 12 0.49 5.17 2.82
151 INT59342 Negative_regulation of NPC1 20 0.44 20.21 2.79
152 INT13600 Binding of Nrm 4 0.36 2.32 2.79
153 INT11139 Gene_expression of LBR 20 0.75 5.13 2.78
154 INT61541 Positive_regulation of Gene_expression of Ngfr 7 0.53 2.87 2.75
155 INT39243 Regulation of TMPO 20 0.61 5.66 2.67
156 INT29064 Gene_expression of Sigmar1 9 0.77 2.48 2.65
157 INT100743 Regulation of KCNH2 6 0.54 2.37 2.61
158 INT27607 Localization of Ptgs1 7 0.59 3.22 2.6
159 INT86602 Binding of KCNH2 14 0.36 4.65 2.58
160 INT153492 Gene_expression of Gmcl1 44 0.65 15.77 2.56
161 INT34969 Negative_regulation of Binding of Ptgs1 4 0.37 1.55 2.55
162 INT17846 Binding of Ptgs2 8 0.32 4.66 2.48
163 INT34905 Positive_regulation of Gene_expression of ALOX5 18 0.50 7.46 2.46
164 INT3475 Regulation of Phosphorylation of Npc1 3 0.36 0 2.45
165 INT70197 Negative_regulation of Positive_regulation of Ptgs1 6 0.24 2.61 2.44
166 INT75225 Transcription of Ngfr 4 0.60 1.95 2.44
167 INT269402 Phosphorylation of TMPO 17 0.32 0.17 2.36
168 INT53476 Positive_regulation of Localization of Ptgs1 6 0.49 2.88 2.35
169 INT6117 Gene_expression of Gmcl1 4 0.49 2.39 2.33
170 INT129742 Regulation of Positive_regulation of Rtn4 2 0.05 2.51 2.33
171 INT9887 Negative_regulation of Gene_expression of Ptgs1 7 0.42 2.94 2.3
172 INT78958 Regulation of Negative_regulation of Ptgs2 6 0.42 2.61 2.3
173 INT16089 Gene_expression of Ltc4s 11 0.77 3.37 2.29
174 INT88241 Positive_regulation of Positive_regulation of Ptgs1 3 0.45 1.71 2.25
175 INT269372 Positive_regulation of Localization of TMPO 19 0.23 0.25 2.23
176 INT2570 Negative_regulation of Gene_expression of Ache 13 0.43 2.88 2.18
177 INT163833 Positive_regulation of Localization of PARP1 7 0.28 7.54 2.14
178 INT54823 Phosphorylation of PTGS1 4 0.51 1.61 2.14
179 INT155928 Positive_regulation of Gene_expression of PARP1 13 0.68 6.54 2.1
180 INT221409 Regulation of Sirt1 8 0.58 5.53 2.1
181 INT32557 Negative_regulation of Negative_regulation of PTGS1 8 0.43 3.44 2.1
182 INT26736 Localization of Alox5 7 0.49 3.72 2.09
183 INT108982 Regulation of Gene_expression of Ptgds 6 0.51 1.64 2.07
184 INT44773 Negative_regulation of LBR 6 0.57 2.32 2.03
185 INT156064 Gene_expression of LMNA 50 0.65 13.38 2.01
186 INT229467 Binding of Ndel1 1 0.45 2.71 2
187 INT161364 Regulation of Faf1 1 0.13 2.42 1.99
188 INT101985 Positive_regulation of Positive_regulation of Ptgs1 4 0.15 4.13 1.98
189 INT20251 Binding of Alox5 7 0.32 5.33 1.93
190 INT64712 Localization of Ngfr 4 0.78 1.19 1.91
191 INT52691 Positive_regulation of Transcription of Ptgs2 5 0.44 3 1.9
192 INT153800 Positive_regulation of Protein_catabolism of PARP1 18 0.49 16.16 1.89
193 INT59194 Gene_expression of STS 18 0.59 6.74 1.89
194 INT10993 Regulation of PARP1 4 0.26 2.04 1.89
195 INT40479 Negative_regulation of SIGMAR1 6 0.52 1.26 1.88
196 INT50743 Positive_regulation of Trpc2 12 0.44 1.99 1.87
197 INT109059 Gene_expression of PRKCZ 2 0.65 0.64 1.87
198 INT107332 Negative_regulation of Regulation of Sigmar1 1 0.19 0 1.86
199 INT95544 Negative_regulation of Itpr1 4 0.59 1.6 1.85
200 INT169862 Regulation of NPC1 13 0.53 13.61 1.84
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