GO:0005643

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Name nuclear pore
Categary Component
Go Slim No
Go Link GO:0005643
Unique Molecular Interactions 146
Total Molecular Interactions 186
Total Single Events 733
Pain Genes Associated 22

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for nuclear pore. They are ordered first by their pain relevance and then by number of times they were reported for nuclear pore. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT167431 Binding of APP and MYO1C 1 0.23 1.38 0.83
2 INT201241 Positive_regulation of GDI2 Positive_regulation of Regulation of AGFG1 1 0.01 0 0.82
3 INT128861 LBR Positive_regulation of Positive_regulation of OPRM1 1 0.19 0.36 0.75
4 INT96765 LBR Positive_regulation of Gene_expression of TP53INP2 1 0.11 0.5 0.62
5 INT176371 LBR Positive_regulation of IL12A 1 0.04 1.22 0.55
6 INT176367 LBR Positive_regulation of IFNA1 1 0.02 1.22 0.55
7 INT143862 Bdnf Positive_regulation of Gene_expression of NUP214 1 0.27 0.61 0.52
8 INT143861 Nfatc1 Regulation of Gene_expression of NUP214 1 0.00 0.61 0.52
9 INT48102 Positive_regulation of LBR Positive_regulation of Positive_regulation of OR7A5 1 0.21 0 0.48
10 INT176366 LBR Regulation of IFNA1 1 0.04 0.91 0.46
11 INT299789 IL4 Negative_regulation of Gene_expression of RAE1 1 0.00 0.84 0.41
12 INT176361 Positive_regulation of LBR Positive_regulation of Gene_expression of IL18 1 0.10 0.84 0.39
13 INT241072 Tpr Positive_regulation of Regulation of Oprm1 1 0.01 0.08 0.36
14 INT278749 NUP98 Positive_regulation of Gene_expression of PTGS2 1 0.46 1.28 0.35
15 INT176363 IFNA1 Regulation of Positive_regulation of LBR 1 0.04 0.69 0.34
16 INT307017 LBR Positive_regulation of Gene_expression of TNF 1 0.02 0.58 0.32
17 INT307014 LBR Positive_regulation of Gene_expression of IL6 1 0.01 0.58 0.32
18 INT21321 Pomc Positive_regulation of LBR 1 0.04 0 0.31
19 INT169612 OGFR Regulation of RAN 1 0.23 0.14 0.3
20 INT169613 OGFR Regulation of IPO5 1 0.03 0.14 0.29
21 INT169615 Regulation of OGFR Regulation of IPO5 1 0.03 0.14 0.29
22 INT18499 Binding of SUMO1 and SEC1 1 0.12 0 0.28
23 INT329528 Seh1l Positive_regulation of Gene_expression of Csf2 1 0.07 0.37 0.28
24 INT168791 Positive_regulation of Binding of AGFG1 and IVNS1ABP 1 0.01 0.39 0.26
25 INT168792 Negative_regulation of Binding of AGFG1 and IVNS1ABP 1 0.01 0.39 0.26
26 INT168790 Binding of AGFG1 and IVNS1ABP 1 0.01 0.39 0.26
27 INT169614 Binding of KPNA1 and OGFR 1 0.06 0.18 0.23
28 INT169611 Binding of RAN and OGFR 1 0.24 0.19 0.23
29 INT64967 Binding of AGFG1 and Alb 1 0.01 0.2 0.2
30 INT198523 Ranbp2 Negative_regulation of Cox11 1 0.42 0 0.17
31 INT198540 Ranbp2 Negative_regulation of HK1 1 0.19 0 0.17
32 INT182326 LBR Positive_regulation of Gene_expression of Birc5 1 0.00 0.46 0.17
33 INT136605 Binding of OPRD1 and RAN 1 0.37 0.54 0.15
34 INT167523 Binding of Pepd and Aaas 1 0.02 0.5 0.15
35 INT136606 Binding of RAN and DLL1 1 0.33 0.45 0.15
36 INT134698 Regulation of Prnp Positive_regulation of Nup214 1 0.26 1.18 0.14
37 INT134697 Prnp Positive_regulation of Nup214 1 0.44 1.18 0.13
38 INT241075 Klf16 Negative_regulation of Tpr 1 0.00 0.13 0.12
39 INT241073 Klf16 Positive_regulation of Tpr 1 0.01 0.13 0.12
40 INT175196 Binding of NCOR1 and NUP62 1 0.02 0.84 0.12
41 INT39207 LBR Positive_regulation of Gene_expression of IL2 1 0.23 0 0.11
42 INT198525 Binding of Kif5b and Ranbp2 1 0.23 0 0.1
43 INT64966 Binding of AGFG1 and Cd24 1 0.00 0.1 0.1
44 INT264839 Positive_regulation of Binding of Eno2 and Tpr 1 0.00 0.17 0.1
45 INT217476 Nup62 Positive_regulation of Ngf 1 0.37 0.52 0.1
46 INT264836 Binding of Eno2 and Tpr 1 0.00 0.17 0.1
47 INT217477 Traf6 Positive_regulation of Binding of Nup62 1 0.32 0.47 0.09
48 INT175195 Binding of SH2B2 and NUP62 1 0.01 0 0.07
49 INT264835 Binding of Creb1 and Tpr 1 0.01 0.05 0.06
50 INT217472 Binding of Nup62 and Mul1 1 0.12 0 0.05
51 INT217471 Binding of Nup62 and Traf6 1 0.26 0 0.05
52 INT217468 Positive_regulation of Binding of Nup62 and Mul1 1 0.16 0 0.05
53 INT307007 MT1JP Positive_regulation of Localization of LBR 1 0.01 0 0.05
54 INT217467 Binding of Nup62 and Tnfrsf11a 1 0.31 0 0.05
55 INT299460 Foxl2 Positive_regulation of Tpr 1 0.01 0.56 0.05
56 INT198533 Ranbp2 Regulation of HK1 1 0.12 0.06 0.04
57 INT241071 Cish Positive_regulation of Tpr 1 0.00 0 0.04
58 INT241076 Binding of Oprm1 and Positive_regulation of Tpr 1 0.01 0 0.04
59 INT198537 Binding of HK1 and Ranbp2 1 0.22 0.05 0.04
60 INT198524 Cox11 Negative_regulation of Ranbp2 1 0.19 0.08 0.04
61 INT323707 LBR Positive_regulation of MIR146A 1 0.02 0.1 0.03
62 INT225585 Regulation of Binding of Med1 and Tpr 1 0.00 0.07 0
63 INT217317 Binding of polymerase and SUMO1 1 0.00 1.7 0
64 INT104864 IL2 Positive_regulation of NXT1 1 0.08 0 0
65 INT268651 NUPL2 Positive_regulation of Gene_expression of LIF 1 0.66 0.07 0
66 INT225583 Binding of Ncoa1 and Tpr 1 0.00 0.07 0
67 INT206085 FDPS Positive_regulation of AGFG1 1 0.00 0.4 0
68 INT278768 NUP98 Negative_regulation of Gene_expression of RAP1A 1 0.41 0.44 0
69 INT225484 Binding of Acp5 and Tpr 1 0.01 0 0
70 INT198541 Ranbp2 Positive_regulation of Binding of HK1 1 0.22 0 0
71 INT217473 Nup62 Regulation of Tnfrsf11a 1 0.38 0.66 0
72 INT278772 NUP98 Regulation of HOXA9 1 0.42 0 0
73 INT278765 Binding of RUNX1 and NUP98 1 0.02 0.26 0
74 INT217788 MIR181A1 Regulation of EIF5A 1 0.23 0.69 0
75 INT314965 Binding of Lbr and Blvrb 1 0.00 0.13 0
76 INT278755 OR51S1 Regulation of NUP98 1 0.00 0 0
77 INT217316 Binding of SUMO1 and ERVW-1 1 0.00 1.55 0
78 INT314971 Binding of ITGAX and Lbr 1 0.05 0.07 0
79 INT104866 ZAK Positive_regulation of NXT1 1 0.07 0 0
80 INT232893 Binding of ABR and Nup62 1 0.03 0.13 0
81 INT298853 Binding of AGFG1 and RILP 1 0.02 0.21 0
82 INT171646 PRSS1 Positive_regulation of NXF1 1 0.34 0.53 0
83 INT198527 Binding of Ranbp2 and Cox11 1 0.47 0 0
84 INT314966 Binding of Lbr and H2 1 0.01 0.07 0
85 INT298866 Binding of AGFG1 and RAB7A 1 0.04 0.21 0
86 INT278753 NUP98 Positive_regulation of KBTBD10 1 0.45 0 0
87 INT175192 Binding of NUP62 and GOPC 1 0.03 0 0
88 INT278750 HOXA9 Regulation of NUP98 1 0.11 0 0
89 INT278752 Binding of NUP98 and HEY1 1 0.48 0 0
90 INT314970 Binding of Cd40 and Lbr 1 0.03 0.07 0
91 INT278770 Binding of NUP98 and KBTBD10 1 0.35 0 0
92 INT278773 NUP98 Regulation of HEY1 1 0.45 0 0
93 INT234790 B4GALNT1 Positive_regulation of AGFG1 1 0.00 0.08 0
94 INT299443 Gene_expression of Foxl2 Positive_regulation of Tpr 1 0.01 0.05 0
95 INT188436 Negative_regulation of NUP62 Positive_regulation of TNFRSF11A 1 0.39 1.6 0
96 INT278767 NUP98 Regulation of Gene_expression of HOXA9 1 0.42 0.23 0
97 INT314969 Binding of Lbr and Mthfd1 1 0.01 0 0
98 INT171647 CTSB Positive_regulation of NXF1 1 0.23 0.47 0
99 INT198526 Ranbp2 Positive_regulation of Hk1 1 0.51 0 0
100 INT104862 NXT1 Positive_regulation of TH1L 1 0.03 0 0
101 INT225541 Binding of Med1 and Tpr 1 0.00 0.07 0
102 INT225547 Binding of Tpr and Cytip 1 0.00 0 0
103 INT175194 Binding of UBC and NUP62 1 0.01 0.05 0
104 INT314964 Binding of Cd86 and Lbr 1 0.03 0.07 0
105 INT278776 NUP98 Regulation of OR51S1 1 0.01 0 0
106 INT175193 NUP62 Regulation of Binding of TRAF6 1 0.07 0.06 0
107 INT278759 Binding of HOXA9 and NUP98 1 0.34 0.06 0
108 INT198529 Ranbp2 Positive_regulation of Cox11 1 0.68 0 0
109 INT288252 Binding of CGA and NUPL2 1 0.15 1 0
110 INT234794 Binding of GDI1 and AGFG1 1 0.01 0 0
111 INT225563 Binding of Tpr and Ep300 1 0.00 0 0
112 INT278762 NUP98 Positive_regulation of PLN 1 0.47 0 0
113 INT298852 Binding of AGFG1 and MTG1 1 0.00 0 0
114 INT299449 Foxl2 Regulation of Tpr 1 0.00 0.26 0
115 INT175191 Binding of TRAF6 and NUP62 1 0.06 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for nuclear pore. They are ordered first by their pain relevance and then by number of times they were reported in nuclear pore. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT79299 Negative_regulation of NXT1 16 0.32 8.27 3.78
2 INT79298 Localization of NXT1 9 0.60 4.9 3.42
3 INT198495 Gene_expression of Ranbp2 1 0.78 3.31 3.14
4 INT48106 Positive_regulation of LBR 11 0.49 5.14 2.86
5 INT172678 Gene_expression of NUPL2 20 0.75 5.06 2.85
6 INT11139 Gene_expression of LBR 20 0.75 5.13 2.78
7 INT53525 Positive_regulation of NXT1 11 0.35 4.81 2.41
8 INT97307 Binding of NXT1 12 0.06 5.67 2.32
9 INT44773 Negative_regulation of LBR 6 0.57 2.32 2.03
10 INT11385 Gene_expression of RAE1 5 0.49 4.16 1.76
11 INT28317 Gene_expression of NXT1 12 0.14 4.57 1.66
12 INT6438 Positive_regulation of RAN 6 0.42 2.09 1.59
13 INT18503 Binding of SUMO1 7 0.27 6.21 1.48
14 INT123413 Positive_regulation of Tpr 7 0.03 1.05 1.25
15 INT77809 Gene_expression of NUP214 3 0.65 1.35 1.24
16 INT329510 Gene_expression of Seh1l 1 0.67 2.95 1.18
17 INT28643 Positive_regulation of Gene_expression of LBR 3 0.11 2.43 1.16
18 INT31805 Localization of LBR 3 0.73 1.23 1.13
19 INT71378 Transcription of LBR 2 0.07 1.34 1.03
20 INT44772 Negative_regulation of Negative_regulation of LBR 2 0.42 0.38 0.92
21 INT201261 Regulation of AGFG1 4 0.09 2.72 0.9
22 INT11386 Positive_regulation of RAE1 3 0.11 1.53 0.83
23 INT198501 Negative_regulation of Ranbp2 1 0.43 0.92 0.78
24 INT234820 Localization of AGFG1 3 0.14 0.86 0.74
25 INT47481 Localization of SUMO1 1 0.01 0 0.73
26 INT127432 Gene_expression of Nup62 20 0.71 11.01 0.71
27 INT165393 Positive_regulation of Localization of NXT1 1 0.07 0.83 0.66
28 INT46148 Binding of LBR 5 0.31 1.58 0.64
29 INT22526 Negative_regulation of Gene_expression of RAE1 2 0.37 1.66 0.62
30 INT307027 Positive_regulation of Localization of LBR 1 0.05 0.82 0.61
31 INT22527 Negative_regulation of RAE1 1 0.00 1.69 0.57
32 INT198506 Negative_regulation of Gene_expression of Ranbp2 1 0.43 0.63 0.54
33 INT175219 Binding of NUP62 31 0.27 4.51 0.53
34 INT176375 Positive_regulation of Positive_regulation of LBR 1 0.10 1.12 0.53
35 INT329516 Negative_regulation of Gene_expression of Seh1l 1 0.37 0.42 0.53
36 INT54893 Positive_regulation of NUPL2 3 0.45 2.31 0.52
37 INT79300 Negative_regulation of Localization of NXT1 2 0.08 1.38 0.52
38 INT57163 Gene_expression of AGFG1 11 0.75 2.45 0.48
39 INT177556 Gene_expression of Tpr 9 0.34 2.71 0.48
40 INT64965 Binding of AGFG1 8 0.10 3.53 0.45
41 INT217452 Binding of Nup62 1 0.38 2.7 0.44
42 INT11728 Binding of NUPL2 3 0.47 3.28 0.42
43 INT198505 Positive_regulation of Gene_expression of Ranbp2 1 0.50 0.49 0.42
44 INT167432 Binding of MYO1C 1 0.19 0.67 0.41
45 INT329526 Positive_regulation of Seh1l 1 0.43 0.73 0.41
46 INT21831 Positive_regulation of Lbr 2 0.37 0 0.39
47 INT3044 Regulation of LBR 2 0.44 0.1 0.35
48 INT198494 Regulation of Ranbp2 1 0.45 0.16 0.35
49 INT303286 Localization of Nup62 1 0.08 0 0.35
50 INT280988 Regulation of Gene_expression of NUPL2 1 0.44 0.07 0.31
51 INT296898 Negative_regulation of Gene_expression of NXT1 1 0.01 0.69 0.31
52 INT329522 Localization of Seh1l 1 0.64 0.34 0.3
53 INT329514 Regulation of Gene_expression of Seh1l 1 0.39 0.65 0.3
54 INT118046 Regulation of RAN 2 0.34 0.14 0.29
55 INT169617 Regulation of IPO5 1 0.05 0.14 0.29
56 INT107163 Negative_regulation of Lbr 1 0.15 0 0.29
57 INT86708 Negative_regulation of SUMO1 3 0.18 1.71 0.28
58 INT76252 Positive_regulation of NUP214 1 0.45 0.17 0.27
59 INT177548 Regulation of Tpr 9 0.01 3.87 0.26
60 INT18500 Negative_regulation of Binding of SUMO1 1 0.32 0 0.26
61 INT217446 Negative_regulation of Binding of Nup62 1 0.33 1.54 0.25
62 INT86709 Positive_regulation of SUMO1 3 0.19 2.59 0.24
63 INT21829 Regulation of Lbr 1 0.04 0 0.24
64 INT198478 Binding of Ranbp2 1 0.48 0.54 0.21
65 INT169619 Negative_regulation of RAN 1 0.28 0.2 0.21
66 INT198483 Localization of Ranbp2 1 0.75 0 0.21
67 INT169621 Gene_expression of RAN 1 0.44 0.18 0.19
68 INT217463 Positive_regulation of Nup62 5 0.39 1.79 0.17
69 INT139676 Positive_regulation of NXF1 1 0.46 0.26 0.17
70 INT139675 Regulation of NXF1 1 0.44 0.26 0.17
71 INT232830 Positive_regulation of Protein_catabolism of Nup62 3 0.39 0.75 0.15
72 INT280989 Negative_regulation of Gene_expression of NUPL2 2 0.41 0.51 0.15
73 INT134696 Regulation of Nup214 1 0.26 1.18 0.14
74 INT329512 Negative_regulation of Seh1l 1 0.37 0.06 0.14
75 INT134695 Negative_regulation of Nup214 1 0.42 1.28 0.14
76 INT64474 Regulation of Positive_regulation of LBR 1 0.22 0.08 0.13
77 INT187958 Regulation of NUPL2 2 0.44 0.13 0.12
78 INT198488 Positive_regulation of Ranbp2 1 0.44 0.27 0.12
79 INT198489 Regulation of Gene_expression of Ranbp2 1 0.45 0.33 0.12
80 INT217454 Positive_regulation of Gene_expression of Nup62 2 0.39 1.56 0.11
81 INT241052 Binding of Tpr 1 0.01 0 0.11
82 INT341478 Gene_expression of SUMO1 1 0.02 0.68 0.11
83 INT198490 Positive_regulation of Localization of Ranbp2 1 0.50 0 0.11
84 INT154235 Gene_expression of KPNA1 2 0.78 1.77 0.1
85 INT92818 Negative_regulation of Localization of NUPL2 1 0.42 0.06 0.1
86 INT200109 Positive_regulation of Gene_expression of NUPL2 1 0.49 0.44 0.1
87 INT92817 Localization of NUPL2 2 0.68 1.05 0.09
88 INT217330 Protein_catabolism of SUMO1 2 0.27 1.67 0.09
89 INT11727 Regulation of Binding of NUPL2 1 0.60 0.09 0.09
90 INT335135 Regulation of Localization of NXT1 1 0.10 0 0.09
91 INT127433 Negative_regulation of Gene_expression of Nup62 2 0.53 2.36 0.08
92 INT55486 Negative_regulation of Positive_regulation of LBR 1 0.41 1.07 0.08
93 INT278803 Gene_expression of NUP98 1 0.72 0.78 0.08
94 INT264421 Positive_regulation of Negative_regulation of SUMO1 1 0.19 0 0.08
95 INT234814 Positive_regulation of AGFG1 6 0.10 2.33 0.07
96 INT232834 Protein_catabolism of Nup62 3 0.56 0.8 0.07
97 INT224949 Regulation of Regulation of Tpr 2 0.01 1.57 0.07
98 INT217461 Negative_regulation of Positive_regulation of Nup62 1 0.33 0.41 0.07
99 INT303974 Phosphorylation of LBR 2 0.79 0.24 0.06
100 INT171652 Binding of NXF1 1 0.20 0.23 0.06
101 INT303973 Negative_regulation of Phosphorylation of LBR 1 0.41 0.14 0.06
102 INT175226 Gene_expression of NUP62 4 0.52 1.26 0.05
103 INT217443 Regulation of Nup62 1 0.48 1.47 0.05
104 INT188456 Negative_regulation of Gene_expression of NUP62 1 0.33 0.99 0.05
105 INT198493 Protein_catabolism of Ranbp2 1 0.88 0.12 0.05
106 INT198500 Positive_regulation of Protein_catabolism of Ranbp2 1 0.50 0.12 0.05
107 INT278784 Regulation of Gene_expression of NUP98 1 0.42 0 0.04
108 INT21830 Localization of Lbr 1 0.14 0 0.04
109 INT298889 Negative_regulation of AGFG1 1 0.04 0.64 0.03
110 INT278793 Phosphorylation of NUP98 1 0.76 0 0.03
111 INT73961 Regulation of NXT1 3 0.01 0.39 0
112 INT219066 Transcription of Tpr 2 0.01 0.1 0
113 INT217457 Negative_regulation of Nup62 2 0.33 0.94 0
114 INT234821 Positive_regulation of Gene_expression of AGFG1 1 0.10 0.07 0
115 INT330661 Regulation of Phosphorylation of LBR 1 0.03 0.1 0
116 INT188443 Negative_regulation of NUP62 1 0.33 1.53 0
117 INT278797 Binding of NUP98 1 0.35 0.3 0
118 INT278801 Positive_regulation of NUP98 1 0.47 0 0
119 INT278789 Regulation of Localization of NUP98 1 0.42 0 0
120 INT217841 Regulation of EIF5A 1 0.53 0.74 0
121 INT217838 Positive_regulation of Regulation of EIF5A 1 0.59 0.74 0
122 INT175215 Negative_regulation of Binding of NUP62 1 0.19 0.13 0
123 INT202415 Binding of NUP214 1 0.01 0.19 0
124 INT278800 Localization of NUP98 1 0.70 0 0
125 INT288256 Protein_catabolism of NUPL2 1 0.86 0.95 0
126 INT278796 Regulation of NUP98 1 0.25 0 0
127 INT219064 Negative_regulation of Tpr 1 0.01 0.79 0
128 INT188454 Positive_regulation of NUP62 1 0.36 0.92 0
129 INT217837 Gene_expression of EIF5A 1 0.51 1.08 0
130 INT234819 Regulation of Binding of AGFG1 1 0.05 0.19 0
131 INT217821 Positive_regulation of EIF5A 1 0.18 0.74 0
132 INT136610 Binding of RAN 1 0.35 0.09 0
133 INT298394 Positive_regulation of Binding of LBR 1 0.05 0.31 0
134 INT234826 Positive_regulation of Regulation of AGFG1 1 0.10 0.87 0
135 INT217347 Positive_regulation of Protein_catabolism of SUMO1 1 0.09 1.67 0
136 INT241058 Protein_catabolism of Tpr 1 0.01 0.16 0
137 INT217459 Regulation of Gene_expression of Nup62 1 0.35 0.35 0
138 INT118047 Regulation of Positive_regulation of RAN 1 0.07 0 0
139 INT234818 Positive_regulation of Binding of AGFG1 1 0.10 0.08 0
140 INT335136 Regulation of Binding of NXT1 1 0.07 0 0
141 INT314951 Binding of Lbr 1 0.04 0.13 0
142 INT341668 Regulation of Gene_expression of NXT1 1 0.01 0 0
143 INT298916 Regulation of Gene_expression of AGFG1 1 0.04 0 0
144 INT314945 Gene_expression of Lbr 1 0.08 0.63 0
145 INT278799 Binding of RAE1 1 0.21 0 0
146 INT288258 Negative_regulation of NUPL2 1 0.41 0.92 0
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