GO:0005652

From wiki-pain
Jump to: navigation, search
Name nuclear lamina
Categary Component
Go Slim No
Go Link GO:0005652
Unique Molecular Interactions 57
Total Molecular Interactions 76
Total Single Events 789
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for nuclear lamina. They are ordered first by their pain relevance and then by number of times they were reported for nuclear lamina. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT177504 Gabrg1 Positive_regulation of PCNA 1 0.07 0.22 0.52
2 INT238632 Binding of EPB41 and Cask 1 0.44 0.78 0.27
3 INT184953 Binding of CDC6 and PCNA 1 0.05 0.19 0.13
4 INT166785 NSMAF Negative_regulation of Gene_expression of PCNA 1 0.30 1.26 0.08
5 INT238631 Regulation of Binding of EPB41 and Cask 1 0.29 0.24 0.07
6 INT238622 Binding of Grin2d and Cask 1 0.05 0 0.04
7 INT176224 Binding of CDKN1A and PCNA 4 0.08 2.52 0.03
8 INT326051 Csf2 Positive_regulation of PCNA 1 0.04 0.17 0.03
9 INT176286 Fasl Positive_regulation of Gene_expression of Pcna 1 0.02 0.81 0.03
10 INT326052 Epo Positive_regulation of PCNA 1 0.04 0.17 0.03
11 INT219412 CDK2 Regulation of PCNA 1 0.20 0.11 0
12 INT238578 Binding of Cask and Sumo1 1 0.26 0.33 0
13 INT238577 Binding of Cask and Sumo2 1 0.13 0 0
14 INT269932 Pcna Negative_regulation of Cdkn2b 1 0.09 0.07 0
15 INT330697 PCNA Regulation of INCENP 1 0.00 0.3 0
16 INT238572 Negative_regulation of Binding of Cask and Sumo1 1 0.23 0.33 0
17 INT326017 Binding of PCNA and HCC 1 0.00 0.99 0
18 INT214902 Binding of Pcna and Trib3 1 0.00 1.51 0
19 INT219405 CCNF Regulation of PCNA 1 0.20 0.11 0
20 INT176289 Pcna Positive_regulation of Phosphorylation of Esr1 1 0.01 0.67 0
21 INT238575 Binding of Cask and Magi1 1 0.04 0.17 0
22 INT314965 Binding of Lbr and Blvrb 1 0.00 0.13 0
23 INT219417 CCNA2 Regulation of PCNA 1 0.10 0.11 0
24 INT218976 Dlst Positive_regulation of Gene_expression of PCNA 1 0.05 0.06 0
25 INT314971 Binding of ITGAX and Lbr 1 0.05 0.07 0
26 INT176288 Binding of Cdk2 and Pcna 1 0.01 0.66 0
27 INT269926 Cdkn2b Negative_regulation of Pcna 1 0.08 0.07 0
28 INT328906 Binding of LMNA and CSAD 1 0.11 0 0
29 INT238570 Regulation of Binding of Cask and Magi1 1 0.03 0.17 0
30 INT314966 Binding of Lbr and H2 1 0.01 0.07 0
31 INT330698 PCNA Regulation of RB1 1 0.00 0.3 0
32 INT176291 Fasl Regulation of Gene_expression of Pcna 1 0.01 0.31 0
33 INT338970 Binding of ING1 and PCNA 1 0.11 0.98 0
34 INT315169 Egfr Negative_regulation of PCNA 1 0.03 0.84 0
35 INT219407 Binding of ESR1 and PCNA 1 0.31 0.31 0
36 INT314970 Binding of Cd40 and Lbr 1 0.03 0.07 0
37 INT315170 Erbb2 Negative_regulation of PCNA 1 0.03 0.84 0
38 INT238579 Binding of Cask and Sumo3 1 0.15 0 0
39 INT188272 Binding of KITLG and PCNA 1 0.01 0.17 0
40 INT238394 Binding of PCNA and SRA1 1 0.00 0.07 0
41 INT269914 Tpt1 Negative_regulation of Pcna 1 0.08 0.07 0
42 INT314969 Binding of Lbr and Mthfd1 1 0.01 0 0
43 INT176290 Fasl Positive_regulation of Pcna 1 0.02 0.44 0
44 INT271096 Pcna Positive_regulation of Akt1 1 0.00 0.34 0
45 INT176282 Binding of Pcna and p53-ps 1 0.00 0.69 0
46 INT314964 Binding of Cd86 and Lbr 1 0.03 0.07 0
47 INT219422 CCNE2 Regulation of PCNA 1 0.10 0.11 0
48 INT269952 Pcna Negative_regulation of Tpt1 1 0.09 0.07 0
49 INT286109 Binding of Pcna and Mutyh 1 0.30 0 0
50 INT238391 ELANE Positive_regulation of PCNA 1 0.01 0.07 0
51 INT238623 Binding of Cask and Cadm1 1 0.09 0.08 0
52 INT238621 Binding of Sdc2 and Cask 1 0.06 0.08 0
53 INT177783 Binding of HDAC1 and PCNA 1 0.09 0.5 0
54 INT269916 Sox17 Positive_regulation of Pcna 1 0.16 0 0
55 INT238630 Negative_regulation of Binding of EPB41 and Cask 1 0.45 0 0
56 INT351708 Binding of LMNA and SAE1 1 0.08 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for nuclear lamina. They are ordered first by their pain relevance and then by number of times they were reported in nuclear lamina. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42
2 INT86369 Positive_regulation of Gene_expression of PCNA 40 0.67 26.66 3.57
3 INT85078 Positive_regulation of PCNA 36 0.49 17.06 2.81
4 INT50558 Negative_regulation of PCNA 31 0.57 13.97 2.3
5 INT101572 Negative_regulation of Gene_expression of PCNA 24 0.53 13.87 2.21
6 INT112868 Gene_expression of Pcna 21 0.75 8.6 2.15
7 INT156064 Gene_expression of LMNA 50 0.65 13.38 2.01
8 INT238608 Gene_expression of Cask 1 0.73 2.74 1.9
9 INT68952 Localization of PCNA 17 0.62 5.64 1.78
10 INT111485 Gene_expression of Pcna 2 0.75 0 0.83
11 INT238602 Binding of Cask 1 0.40 0.9 0.63
12 INT100065 Negative_regulation of LMNA 12 0.49 0.12 0.56
13 INT169957 Transcription of PCNA 7 0.34 0.94 0.55
14 INT111484 Positive_regulation of Gene_expression of Pcna 1 0.67 0 0.54
15 INT238589 Phosphorylation of Cask 1 0.77 0.13 0.52
16 INT176264 Binding of PCNA 21 0.21 9.08 0.51
17 INT241674 Negative_regulation of Transcription of PCNA 1 0.11 0.33 0.47
18 INT139399 Regulation of Gene_expression of PCNA 14 0.56 6.06 0.43
19 INT101568 Negative_regulation of Pcna 1 0.41 5.24 0.42
20 INT21831 Positive_regulation of Lbr 2 0.37 0 0.39
21 INT238618 Positive_regulation of Cask 1 0.66 0.4 0.35
22 INT139391 Regulation of PCNA 10 0.60 3.12 0.33
23 INT118955 Phosphorylation of PCNA 4 0.29 1.54 0.33
24 INT214842 Positive_regulation of LMNA 14 0.45 2.98 0.31
25 INT238592 Positive_regulation of Phosphorylation of Cask 1 0.41 0 0.31
26 INT107163 Negative_regulation of Lbr 1 0.15 0 0.29
27 INT21829 Regulation of Lbr 1 0.04 0 0.24
28 INT279230 Regulation of Gene_expression of LMNA 1 0.02 0.22 0.22
29 INT136488 Regulation of LMNA 13 0.60 3.53 0.2
30 INT216124 Negative_regulation of Pcna 3 0.13 2.06 0.19
31 INT188239 Binding of LMNA 20 0.47 6.58 0.18
32 INT238611 Localization of Cask 1 0.76 0.67 0.18
33 INT238597 Positive_regulation of Gene_expression of Cask 1 0.66 0.88 0.17
34 INT238422 Positive_regulation of Positive_regulation of PCNA 4 0.20 2.92 0.13
35 INT256849 Regulation of Pcna 1 0.05 0.3 0.13
36 INT238613 Negative_regulation of Gene_expression of Cask 1 0.41 0.12 0.12
37 INT125588 Positive_regulation of Gene_expression of Pcna 5 0.49 1.57 0.11
38 INT238590 Negative_regulation of Binding of Cask 1 0.41 0.23 0.1
39 INT238615 Positive_regulation of Binding of Cask 1 0.47 0.06 0.09
40 INT238588 Regulation of Binding of Cask 1 0.43 0.15 0.07
41 INT269893 Negative_regulation of Gene_expression of Pcna 2 0.18 0.86 0.04
42 INT21830 Localization of Lbr 1 0.14 0 0.04
43 INT273404 Positive_regulation of Localization of PCNA 2 0.36 0.09 0.03
44 INT306289 Regulation of Positive_regulation of PCNA 1 0.06 0.07 0.03
45 INT176239 Regulation of Gene_expression of Pcna 1 0.04 0.58 0.03
46 INT222330 Localization of LMNA 14 0.55 0.23 0
47 INT176250 Positive_regulation of Pcna 6 0.13 3.52 0
48 INT314524 Negative_regulation of Gene_expression of LMNA 3 0.41 0 0
49 INT222331 Positive_regulation of Binding of LMNA 2 0.42 0.09 0
50 INT169956 Positive_regulation of Transcription of PCNA 2 0.10 0.09 0
51 INT328908 Positive_regulation of Gene_expression of LMNA 2 0.37 0 0
52 INT201643 Binding of Pcna 2 0.36 0 0
53 INT238425 Negative_regulation of Positive_regulation of PCNA 2 0.05 1.39 0
54 INT272637 Positive_regulation of Positive_regulation of LMNA 1 0.03 0.26 0
55 INT238601 Protein_catabolism of Cask 1 0.62 0 0
56 INT351713 Regulation of Binding of LMNA 1 0.38 0 0
57 INT238593 Negative_regulation of Cask 1 0.41 0.32 0
58 INT271087 Phosphorylation of Pcna 1 0.01 0.65 0
59 INT114219 Positive_regulation of Pcna 1 0.06 0.45 0
60 INT201631 Localization of Pcna 1 0.01 0.5 0
61 INT351710 Protein_catabolism of LMNA 1 0.83 0.06 0
62 INT238594 Positive_regulation of Localization of Cask 1 0.44 0 0
63 INT238600 Regulation of Cask 1 0.43 0.06 0
64 INT176244 Regulation of Pcna 1 0.02 0.31 0
65 INT272638 Negative_regulation of Regulation of LMNA 1 0.02 0 0
66 INT314523 Transcription of LMNA 1 0.58 0 0
67 INT314951 Binding of Lbr 1 0.04 0.13 0
68 INT252988 Negative_regulation of Binding of PCNA 1 0.06 1.25 0
69 INT314945 Gene_expression of Lbr 1 0.08 0.63 0
70 INT222329 Negative_regulation of Localization of LMNA 1 0.20 0 0
71 INT288825 Positive_regulation of Binding of PCNA 1 0.06 1.29 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox