GO:0005665

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Name DNA-directed RNA polymerase II, core complex
Categary Component
Go Slim No
Go Link GO:0005665
Unique Molecular Interactions 18
Total Molecular Interactions 20
Total Single Events 101
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for DNA-directed RNA polymerase II, core complex. They are ordered first by their pain relevance and then by number of times they were reported for DNA-directed RNA polymerase II, core complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT167655 Binding of Polr2f and Ep300 1 0.01 0.06 0.51
2 INT167654 Binding of Polr2f and Ngf 1 0.03 0.06 0.51
3 INT199284 Binding of Polr2a and Vmn1r66 1 0.00 0.19 0.11
4 INT278212 Binding of Polr2a and Cytip 1 0.06 0.07 0.04
5 INT332944 Binding of HAT1 and Polr2a 1 0.00 0.27 0.03
6 INT313120 Positive_regulation of Binding of Polr2a and Carf 1 0.06 0.69 0
7 INT204325 Binding of PPARGC1A and SIRT1 1 0.39 0.19 0
8 INT217779 POLR2B Regulation of Gene_expression of RASGRP1 1 0.01 0.2 0
9 INT217785 POLR2B Regulation of Gene_expression of MAP3K3 1 0.06 0.2 0
10 INT204322 Binding of ADIPOQ and Positive_regulation of Gene_expression of PPARGC1A 1 0.30 0.07 0
11 INT313115 Binding of Polr2a and Carf 1 0.05 0.69 0
12 INT204326 SIRT1 Positive_regulation of PPARGC1A 1 0.51 0.19 0
13 INT352860 Positive_regulation of POLR2B Positive_regulation of Positive_regulation of IKBKAP 1 0.03 0.74 0
14 INT301472 Binding of Polr2a and Smyd3 1 0.06 0.08 0
15 INT208139 Binding of PITX1 and URI1 1 0.01 0.62 0
16 INT342096 Binding of Polr2f and Ehmt1 1 0.00 0.73 0
17 INT204319 SIRT1 Regulation of Gene_expression of PPARGC1A 1 0.50 0.12 0
18 INT301476 Binding of Polr2a and Smyd2 1 0.08 0.13 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for DNA-directed RNA polymerase II, core complex. They are ordered first by their pain relevance and then by number of times they were reported in DNA-directed RNA polymerase II, core complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT139546 Gene_expression of URI1 3 0.75 3 1.49
2 INT247615 Binding of URI1 2 0.20 1.17 1.13
3 INT167649 Positive_regulation of Polr2f 2 0.07 0.2 0.55
4 INT130141 Phosphorylation of POLR2B 1 0.29 0.57 0.47
5 INT249457 Positive_regulation of URI1 3 0.27 0.8 0.45
6 INT204348 Gene_expression of PPARGC1A 10 0.75 2.73 0.19
7 INT315759 Regulation of URI1 1 0.01 0.12 0.19
8 INT338841 Regulation of Polr2a 1 0.01 0.08 0.17
9 INT338840 Protein_catabolism of Polr2a 1 0.02 0.08 0.17
10 INT219057 Gene_expression of Polr2f 8 0.13 1.58 0.16
11 INT200282 Phosphorylation of Polr2a 1 0.04 0.14 0.15
12 INT219062 Positive_regulation of Gene_expression of Polr2f 1 0.07 0.42 0.13
13 INT190557 Transcription of Polr2a 1 0.09 0.51 0.12
14 INT241879 Transcription of Polr2f 3 0.15 1.91 0.08
15 INT204332 Positive_regulation of PPARGC1A 7 0.67 1.42 0.07
16 INT293405 Transcription of URI1 1 0.03 0.74 0.07
17 INT346683 Protein_catabolism of URI1 1 0.19 0.15 0.05
18 INT301441 Binding of Polr2a 3 0.10 0.41 0.03
19 INT175888 Gene_expression of POLR2B 2 0.04 0.32 0.03
20 INT250504 Negative_regulation of URI1 1 0.10 0.71 0.03
21 INT204372 Transcription of PPARGC1A 3 0.67 0.28 0
22 INT298408 Transcription of POLR2B 3 0.12 2.78 0
23 INT175893 Regulation of POLR2B 2 0.08 1.34 0
24 INT204346 Positive_regulation of Transcription of PPARGC1A 2 0.49 0.28 0
25 INT175901 Negative_regulation of POLR2B 1 0.00 0.34 0
26 INT298404 Regulation of Transcription of POLR2B 1 0.05 1.02 0
27 INT204350 Negative_regulation of Transcription of PPARGC1A 1 0.41 0.1 0
28 INT204333 Regulation of PPARGC1A 1 0.26 0.34 0
29 INT182396 Localization of Polr2f 1 0.01 0.19 0
30 INT352861 Positive_regulation of Transcription of POLR2B 1 0.04 0.73 0
31 INT204357 Positive_regulation of Positive_regulation of PPARGC1A 1 0.49 0.07 0
32 INT204347 Positive_regulation of Negative_regulation of PPARGC1A 1 0.49 0 0
33 INT204369 Negative_regulation of Positive_regulation of PPARGC1A 1 0.41 0.07 0
34 INT346970 Binding of POLR2B 1 0.03 0.36 0
35 INT352872 Positive_regulation of POLR2B 1 0.05 0.72 0
36 INT204366 Positive_regulation of Gene_expression of PPARGC1A 1 0.67 1.44 0
37 INT204337 Regulation of Gene_expression of PPARGC1A 1 0.44 0.48 0
38 INT204339 Binding of PPARGC1A 1 0.35 0.19 0
39 INT204329 Positive_regulation of Regulation of PPARGC1A 1 0.45 0.07 0
40 INT263260 Negative_regulation of Polr2f 1 0.01 0.12 0
41 INT204341 Negative_regulation of Gene_expression of PPARGC1A 1 0.41 0 0
42 INT204351 Negative_regulation of PPARGC1A 1 0.42 0.25 0
43 INT346682 Positive_regulation of Gene_expression of URI1 1 0.14 0.27 0
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