GO:0005740

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Name mitochondrial envelope
Categary Component
Go Slim No
Go Link GO:0005740
Unique Molecular Interactions 50
Total Molecular Interactions 62
Total Single Events 939
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for mitochondrial envelope. They are ordered first by their pain relevance and then by number of times they were reported for mitochondrial envelope. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
2 INT97056 Cpz Regulation of Gene_expression of Bcl2l1 1 0.22 0.57 0.83
3 INT83800 Aap Regulation of Gene_expression of Bcl2l1 1 0.28 0.58 0.64
4 INT340110 MAOB Positive_regulation of Ltp 1 0.02 0.59 0.49
5 INT172901 Binding of Bad and Bcl2l1 3 0.13 6.51 0.27
6 INT180600 MAOB Positive_regulation of TAC1 1 0.00 0.13 0.22
7 INT333396 CFD Positive_regulation of Bcl2l1 1 0.05 0.98 0.13
8 INT172899 Binding of Bcl2 and Bcl2l1 3 0.02 5.54 0.12
9 INT200213 PAH Positive_regulation of SDHD 1 0.21 2.43 0.1
10 INT242324 Lep Regulation of Gene_expression of Ucp1 1 0.58 1.47 0.09
11 INT275184 Bad Positive_regulation of Positive_regulation of Bcl2l1 1 0.12 0.62 0.09
12 INT147774 Binding of HLA-B and ABCB6 2 0.40 1.03 0.08
13 INT300246 Binding of ABCB6 and HSR 1 0.11 1.86 0.08
14 INT227301 Zbp1 Regulation of Transcription of Ucp1 1 0.19 1.42 0.08
15 INT262161 Nr1i2 Positive_regulation of Gene_expression of Cyp27a1 1 0.29 0.24 0.07
16 INT242482 Ciapin1 Positive_regulation of Gene_expression of Bcl2l1 1 0.31 1.05 0.07
17 INT237085 Binding of Bnip3l and Vcp 1 0.31 3.53 0.05
18 INT304172 Il5 Positive_regulation of Bcl2l1 1 0.02 0.91 0.05
19 INT340394 Binding of Bax and Bbc3 1 0.01 0.36 0.04
20 INT106486 Gene_expression of CD177 Negative_regulation of Gene_expression of Bcl2l1 1 0.01 1.87 0.04
21 INT237086 Binding of Bnip3l and Itm2b 1 0.28 1.66 0.03
22 INT237090 Binding of App and Bnip3l 1 0.18 1.66 0.03
23 INT237089 Binding of Bnip3l and Atp6v0a4 1 0.12 1.67 0.03
24 INT172906 Binding of Bax and Bcl2l1 2 0.16 2.03 0
25 INT285031 Binding of Bcl2 and Bcl2l1 1 0.27 0.1 0
26 INT295920 Mir761 Positive_regulation of Transcription of Bcl2l1 1 0.00 1.43 0
27 INT241120 Binding of Sdhc and Sdhd 1 0.00 1.28 0
28 INT185849 Binding of BCL2L1 and BIK 1 0.29 0.59 0
29 INT285029 Binding of Bax and Bcl2l1 1 0.25 0.1 0
30 INT333261 Binding of Bcl2l1 and Mcl1 1 0.02 1.25 0
31 INT296956 NRIP1 Regulation of Gene_expression of CIDEA 1 0.44 0.76 0
32 INT265342 sb Negative_regulation of Bcl2l1 1 0.00 0.65 0
33 INT286043 Wwox Positive_regulation of Negative_regulation of Bcl2l1 1 0.04 0.7 0
34 INT296955 Binding of CIDEA and MLST8 1 0.02 0.97 0
35 INT201761 BIK Positive_regulation of Positive_regulation of Bax 1 0.01 0.43 0
36 INT340919 Binding of Fkbp8 and Ptplad1 1 0.14 0.17 0
37 INT185855 Binding of BAX and BIK 1 0.29 0.65 0
38 INT296957 NRIP1 Regulation of Transcription of CIDEA 1 0.44 0.91 0
39 INT227697 Stat3 Regulation of Bcl2l1 1 0.05 1.29 0
40 INT333695 Trp53 Positive_regulation of Localization of Bcl2l1 1 0.23 1.33 0
41 INT333691 Trp53 Positive_regulation of Bcl2l1 1 0.23 1.33 0
42 INT193953 Binding of Bcl2l1 and Psen1 1 0.07 0.66 0
43 INT254699 Positive_regulation of Map2k2 Regulation of Bcl2l1 1 0.04 0.89 0
44 INT193960 Binding of Bcl2l1 and Ps 1 0.01 0.6 0
45 INT193957 Binding of Bcl2l1 and Psen2 1 0.07 0.66 0
46 INT282998 Binding of Bcl2 and Bbc3 1 0.00 0.43 0
47 INT313074 Binding of Bnip3 and Map1lc3a 1 0.01 0.26 0
48 INT254091 EPO Positive_regulation of Gene_expression of Bcl2l1 1 0.11 0.66 0
49 INT352149 Ift88 Negative_regulation of Bcl2l1 1 0.00 0.19 0
50 INT185853 Binding of BCL2 and BIK 1 0.36 0.59 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for mitochondrial envelope. They are ordered first by their pain relevance and then by number of times they were reported in mitochondrial envelope. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT83797 Gene_expression of Bcl2l1 124 0.77 94.55 22.39
2 INT635 Negative_regulation of MAOB 51 0.59 24.5 12.66
3 INT99505 Gene_expression of Bcl2l1 42 0.77 33.12 10.15
4 INT99506 Negative_regulation of Bcl2l1 25 0.58 15.7 6.09
5 INT99507 Positive_regulation of Bcl2l1 17 0.69 9.23 4.97
6 INT116614 Positive_regulation of Gene_expression of Bcl2l1 12 0.67 11.39 4.68
7 INT200218 Localization of SDHD 1 0.69 48.58 4.57
8 INT78719 Binding of Ucp1 8 0.41 8.93 4.5
9 INT83794 Positive_regulation of Gene_expression of Bcl2l1 26 0.69 16.89 4.28
10 INT35744 Binding of MAOB 13 0.46 7.52 4.26
11 INT83798 Negative_regulation of Gene_expression of Bcl2l1 28 0.58 20.26 4.21
12 INT83796 Regulation of Gene_expression of Bcl2l1 10 0.61 7.85 4.05
13 INT95423 Negative_regulation of Bcl2l1 26 0.41 21.66 3.81
14 INT9295 Regulation of MAOB 12 0.56 3.32 3.6
15 INT86245 Positive_regulation of Bcl2l1 15 0.46 12.67 3.11
16 INT99508 Regulation of Bcl2l1 12 0.61 10.44 2.71
17 INT66332 Gene_expression of Ucp1 40 0.75 40.09 2.48
18 INT112974 Gene_expression of Ucp1 12 0.78 7.72 2.45
19 INT155218 Binding of ABCB6 18 0.35 13.93 2.25
20 INT83799 Phosphorylation of Bcl2l1 8 0.82 7.86 2.23
21 INT101645 Regulation of Gene_expression of Bcl2l1 8 0.36 5.27 2.05
22 INT53998 Positive_regulation of MAOB 8 0.61 1.22 2
23 INT119896 Negative_regulation of Gene_expression of Ucp1 4 0.58 2.36 1.57
24 INT18521 Localization of MAOB 6 0.71 1.46 1.56
25 INT198852 Positive_regulation of Ucp1 8 0.61 8 1.53
26 INT106413 Transcription of Bcl2l1 8 0.53 3.35 1.52
27 INT115659 Gene_expression of ABCB6 29 0.75 13.59 1.43
28 INT105881 Phosphorylation of Bcl2l1 3 0.51 1.99 1.31
29 INT135806 Regulation of Bcl2l1 10 0.44 7.21 1.05
30 INT242372 Positive_regulation of Negative_regulation of MAOB 2 0.35 1.85 1.05
31 INT164863 Positive_regulation of Phosphorylation of Bcl2l1 1 0.31 0.57 1.01
32 INT171435 Gene_expression of SDHD 14 0.58 26.55 0.91
33 INT84964 Gene_expression of MAOB 14 0.61 2.8 0.89
34 INT200222 Positive_regulation of Localization of SDHD 1 0.43 7.07 0.84
35 INT121666 Positive_regulation of Gene_expression of Ucp1 14 0.67 11.62 0.75
36 INT200216 Binding of SDHD 3 0.37 4.51 0.71
37 INT131567 Negative_regulation of Positive_regulation of Bcl2l1 1 0.41 0.66 0.7
38 INT131568 Positive_regulation of Positive_regulation of Bcl2l1 1 0.48 0.64 0.68
39 INT63891 Negative_regulation of Ucp1 4 0.51 1.96 0.63
40 INT157858 Transcription of Ucp1 4 0.70 9.69 0.61
41 INT219026 Positive_regulation of Localization of MAOB 1 0.01 0.39 0.61
42 INT86246 Binding of Bcl2l1 8 0.37 6.67 0.57
43 INT152057 Negative_regulation of Transcription of Bcl2l1 3 0.43 1 0.55
44 INT120699 Negative_regulation of Negative_regulation of MAOB 1 0.43 0.26 0.54
45 INT152058 Regulation of Transcription of Bcl2l1 2 0.32 0.53 0.5
46 INT165799 Negative_regulation of Gene_expression of Bcl2l1 6 0.41 5.12 0.47
47 INT106415 Positive_regulation of Transcription of Bcl2l1 1 0.20 0.49 0.46
48 INT185894 Gene_expression of BIK 24 0.77 21.03 0.45
49 INT152056 Negative_regulation of Regulation of Bcl2l1 1 0.58 0.07 0.45
50 INT227260 Regulation of Gene_expression of Ucp1 6 0.60 5.42 0.44
51 INT53997 Transcription of MAOB 3 0.61 1.51 0.44
52 INT139827 Negative_regulation of ABCB6 5 0.57 2.91 0.43
53 INT200221 Positive_regulation of SDHD 3 0.43 6.59 0.42
54 INT112978 Positive_regulation of Gene_expression of Ucp1 5 0.46 3.56 0.41
55 INT105885 Binding of Bcl2l1 2 0.05 1.13 0.35
56 INT347843 Protein_catabolism of MAOB 2 0.09 0.39 0.33
57 INT350393 Negative_regulation of Protein_catabolism of MAOB 1 0.04 0.4 0.33
58 INT262096 Gene_expression of Cyp27a1 1 0.30 1.21 0.32
59 INT157857 Negative_regulation of Transcription of Ucp1 1 0.57 0.85 0.31
60 INT112976 Transcription of Ucp1 3 0.46 1 0.3
61 INT140116 Binding of Sdhd 2 0.04 2.78 0.3
62 INT58744 Regulation of Negative_regulation of MAOB 1 0.43 0.26 0.29
63 INT149998 Positive_regulation of Positive_regulation of Bcl2l1 1 0.05 1.73 0.28
64 INT228124 Positive_regulation of Bbc3 3 0.49 2.29 0.24
65 INT216554 Localization of ABCB6 5 0.28 0.75 0.23
66 INT115663 Regulation of Gene_expression of ABCB6 1 0.44 1.2 0.21
67 INT282970 Gene_expression of Bbc3 2 0.02 2.83 0.2
68 INT227671 Protein_catabolism of Bcl2l1 2 0.18 0.96 0.19
69 INT356122 Regulation of Phosphorylation of Bcl2l1 1 0.09 0.69 0.19
70 INT132665 Negative_regulation of Ucp1 4 0.59 2.29 0.18
71 INT180601 Regulation of Binding of MAOB 1 0.03 0.12 0.18
72 INT185892 Binding of BIK 1 0.37 2.6 0.18
73 INT112975 Positive_regulation of Ucp1 2 0.70 0.47 0.15
74 INT112977 Positive_regulation of Transcription of Ucp1 2 0.33 0.54 0.15
75 INT121667 Phosphorylation of Ucp1 1 0.04 1.03 0.15
76 INT200215 Transcription of SDHD 1 0.59 1.35 0.15
77 INT282973 Binding of Bbc3 2 0.01 2.87 0.13
78 INT185903 Negative_regulation of Gene_expression of BIK 1 0.43 2.29 0.12
79 INT242323 Localization of Ucp1 1 0.67 1.75 0.1
80 INT300253 Negative_regulation of Gene_expression of ABCB6 2 0.18 0.74 0.09
81 INT300261 Positive_regulation of ABCB6 9 0.22 5.82 0.08
82 INT171434 Positive_regulation of Gene_expression of SDHD 2 0.10 3.87 0.08
83 INT262048 Positive_regulation of Gene_expression of Cyp27a1 1 0.18 0.68 0.08
84 INT132666 Positive_regulation of Negative_regulation of Ucp1 1 0.50 0.27 0.08
85 INT262099 Negative_regulation of Gene_expression of Cyp27a1 1 0.17 0.68 0.08
86 INT340388 Negative_regulation of Gene_expression of Bbc3 1 0.01 0.73 0.08
87 INT338438 Regulation of Binding of ABCB6 1 0.12 0.06 0.08
88 INT185875 Positive_regulation of Gene_expression of BIK 1 0.69 5.23 0.07
89 INT227269 Negative_regulation of Gene_expression of Ucp1 7 0.48 6.54 0.06
90 INT281803 Regulation of Ucp1 4 0.57 4.03 0.05
91 INT300258 Phosphorylation of ABCB6 1 0.24 1.02 0.05
92 INT273064 Positive_regulation of Positive_regulation of MAOB 1 0.46 0.12 0.05
93 INT254082 Positive_regulation of Localization of Bcl2l1 1 0.09 0.16 0.05
94 INT296966 Positive_regulation of CIDEA 1 0.40 2.61 0.05
95 INT254081 Localization of Bcl2l1 1 0.13 0 0.04
96 INT187894 Positive_regulation of Gene_expression of ABCB6 5 0.19 1.97 0.03
97 INT183459 Phosphorylation of Ucp1 1 0.31 0.71 0.03
98 INT185910 Positive_regulation of BIK 1 0.49 1.03 0.03
99 INT237065 Positive_regulation of Bnip3l 1 0.37 1.63 0.03
100 INT124649 Transcription of Bcl2l1 2 0.65 0.16 0
101 INT315141 Localization of Bcl2l1 2 0.36 2.39 0
102 INT200798 Positive_regulation of Phosphorylation of Bcl2l1 1 0.34 0.25 0
103 INT330044 Regulation of Regulation of Bcl2l1 1 0.16 0.76 0
104 INT285019 Positive_regulation of Negative_regulation of Bcl2l1 1 0.28 0.06 0
105 INT284070 Negative_regulation of Phosphorylation of Bcl2l1 1 0.10 1.07 0
106 INT191053 Positive_regulation of Transcription of Bcl2l1 1 0.47 0.08 0
107 INT343776 Regulation of Gene_expression of SDHD 1 0.00 0.16 0
108 INT124648 Regulation of Transcription of Bcl2l1 1 0.31 0.09 0
109 INT296988 Positive_regulation of Transcription of CIDEA 1 0.52 1.59 0
110 INT272180 Regulation of Gene_expression of Ucp1 1 0.30 0.58 0
111 INT300264 Positive_regulation of Positive_regulation of ABCB6 1 0.19 0.99 0
112 INT208960 Positive_regulation of Gene_expression of MAOB 1 0.04 0.15 0
113 INT185885 Regulation of BIK 1 0.45 1.39 0
114 INT254679 Negative_regulation of Positive_regulation of Bbc3 1 0.00 0.72 0
115 INT300256 Regulation of Positive_regulation of ABCB6 1 0.17 1.31 0
116 INT181832 Positive_regulation of Transcription of Ucp1 1 0.67 0.62 0
117 INT185878 Phosphorylation of BIK 1 0.80 1.92 0
118 INT124647 Negative_regulation of Negative_regulation of Bcl2l1 1 0.29 0.08 0
119 INT296968 Transcription of CIDEA 1 0.61 2.48 0
120 INT337961 Gene_expression of Bnip3 1 0.51 0.89 0
121 INT300259 Negative_regulation of Positive_regulation of ABCB6 1 0.16 0.9 0
122 INT171689 Protein_catabolism of Bcl2l1 1 0.38 0.67 0
123 INT296976 Positive_regulation of Gene_expression of CIDEA 1 0.35 0.65 0
124 INT300252 Regulation of ABCB6 1 0.17 0 0
125 INT191057 Regulation of Binding of Bcl2l1 1 0.37 0.74 0
126 INT315142 Negative_regulation of Localization of Bcl2l1 1 0.20 1.2 0
127 INT282980 Negative_regulation of Binding of Bbc3 1 0.01 0.7 0
128 INT296972 Gene_expression of CIDEA 1 0.66 4.23 0
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